A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
N(6)-Carboxymethyllysine (CML), also known as N(epsilon)-(carboxymethyl)lysine, is an advanced glycation endproduct(AGE). CML has been the most used marker for AGEs in food analysis. Uses: Cel and cml are two stable, nonenzymatic chemical modifications of protein lysine residues resulting from glycation and oxidation reactions. Synonyms: Lys(Cm); 2-Amino-6-(carboxymethyl-amino)-hexanoic Acid; N6-(Carboxymethyl)lysine; N6-(Carboxymethyl)-L-lysine; CML; Nε-(1-Carboxymethyl)-L-lysine; Ne-Carboxymethyl-L-lysine; NECML; N(epsilon)-(Carboxymethyl)lysine; (S)-2-Amino-6-(carboxymethylamino)hexanoic acid; (2S)-2-amino-6-(carboxymethylamino)hexanoic acid; n'-(carboxymethyl)lysine. Grade: ≥ 97% (Assay by titration). CAS No. 5746-4-3. Molecular formula: C8H16N2O4. Mole weight: 204.22.
Nε-Crotonyl-L-lysine
A reagent used in peptide synthesis and drug screening. Synonyms: L-Lys(crotonyl)-OH; (S)-2-Amino-6-(but-2-enamido)hexanoic acid; N6-(1-Oxo-2-buten-1-yl)-L-lysine. Grade: ≥ 99% (HPLC). CAS No. 1338823-35-0. Molecular formula: C10H18N2O3. Mole weight: 214.20.
N-ε-Isopropyl-L-lysine is an alkylated version of Lysine. H-Lysine(Isopropyl)-OH was found in the plasma and urine of rats fed with isopropylated casein. Synonyms: H-Lys(Isopropyl)-OH. CAS No. 5977-9-3. Molecular formula: C9H20N2O2. Mole weight: 188.27.
Nepsilon,Nepsilon,Nepsilon-Trimethyl-[13C3]-L-lysine hydrochloride is an isotopic labelled derivative of L-lysine. L-Lysine is an essential amino acid obtained from red meats and fish. Lysine inhibits HSV growth via knocking out arginine. It is also used in the labelling of human bone marrow mesenchymal stem cells for analysis. Synonyms: Nepsilon,Nepsilon,Nepsilon-Trimethyl-13C3-L-lysine hydrochloride; Nε,Nε,Nε-Trimethyl-13C3-L-lysine hydrochloride. Grade: 97% by HPLC; 99% atom 13C. Molecular formula: C6[13C]3H20N2O2.HCl. Mole weight: 227.71.
Used in the preparation of lipophilic human glucagon-like peptide-1 derivatives with protracted action profiles. Group: Biochemicals. Alternative Names: Nε-Palmitoyl-Glu-γ-succinimidyl-α-tert-butyl Ester; (2S)-. Grades: Highly Purified. CAS No. 204521-63-1. Pack Sizes: 100mg. US Biological Life Sciences.
A modified amino acid (L-lysine) for cancer therapy development. Synonyms: H-L-Lys(Poc) HCl; (S)-Amino-6-((prop-2-ynyloxy)carbonylamino)hexanoic acid hydrochloride; H-L-Lys(Pryoc)-OH HCl. Grade: 98.0-101.5% (Assay by titration). CAS No. 1428330-91-9. Molecular formula: C10H16N2O4·HCl. Mole weight: 264.70.
N-ε-propargyloxycarbonyl-L-lysine hydrochloride
N-?-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-?-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals[1][2]. N-?-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: H-?L-?Lys(Poc)?-?OH hydrochloride. CAS No. 1428330-91-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128676.
NeQuinate. Group: Biochemicals. Grades: Highly Purified. CAS No. 13997-19-8. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
Nequinate-[d7]
Nequinate-[d7] is the labelled analogue of Nequinate, which is a medication used for the treatment of coccidiosis. It is only approved for veterinary use in some countries. Synonyms: Nequinate-D7; Methyl 6-Butyl-4-oxo-7-((phenyl-d5)methoxy-d2)-1,4-dihydroquinoline-3-carboxylate; 7-Benzyloxy-D7-6-butyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid methyl ester; Methyl benzoquate-d7; Statil-d7; Statoquate-d7; Statyl-d7; Tranil-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1584701-10-9. Molecular formula: C22H16D7NO4. Mole weight: 372.47.
Neramexane mesylate
Neramexane mesylate. Group: Biochemicals. Grades: Highly Purified. CAS No. 457068-92-7. Pack Sizes: 50g, 100g. Molecular Formula: C11H23N·CH4O3S. US Biological Life Sciences.
Worldwide
Nerandomilast
Nerandomilast (BI 1015550) is an orally active inhibitor of PDE4B with an IC 50 value of 7.2 nM. Nerandomilast has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 1015550. CAS No. 1423719-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153192.
Neratinib
Neratinib, also known as HKI-272 or PB272, is an orally available, 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor. Treatment of cells with this agent results in inhibition of downstream signal transduction events and cell cycle regulatory pathways; arrest at the G1-S (Gap 1/DNA synthesis)-phase transition of the cell division cycle; and ultimately decreased cellular proliferation. Neratinib also inhibits the epidermal growth factor receptor (EGFR) kinase and the proliferation of EGFR-dependent cells. Alternative Names: HKI-272. Neratinib (HKI-272). Nerlynx. CAS No. 698387-09-6. Product ID: API698387096. Molecular formula: C30H29ClN6O3. Mole weight: 557. EINECS: 811-237-1. SMILES: CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C. Appearance: Solid powder. Category: Anti-Tumor APIs.
Neratinib
Neratinib (HKI-272) is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC 50 s of 59 nM and 92 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HKI-272. CAS No. 698387-09-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-32721.
Neratinib
Neratinib. Group: Biochemicals. Alternative Names: (2E) -N-[4-[[3-Chloro-4- (2-pyridinylmethoxy) phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4- (dimethylamino) -2-butenamide; HKI 272. Grades: Highly Purified. CAS No. 698387-09-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Neratinib Impurity 33
Neratinib Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1222172-49-7. Molecular formula: C12H16N2O4. Mole weight: 252.27. Catalog: APB1222172497.
Neratinib Impurity 34
Neratinib Impurity 34. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1222172-50-0. Molecular formula: C15H17N3O4. Mole weight: 303.32. Catalog: APB1222172500.
Neratinib Impurity 6
Neratinib Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102137-46-2. Molecular formula: C12H12N2O. Mole weight: 200.24. Catalog: APB102137462.
Neratinib Impurity 8
Neratinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 105326-69-0. Molecular formula: C12H11ClN2O. Mole weight: 234.68. Catalog: APB105326690.
Neratinib maleate
Neratinib (HKI-272) maleate is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC 50 s of 59 nM and 92 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HKI-272 maleate. CAS No. 915942-22-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32721B.
Neratinib Maleate
Neratinib Maleate is the maleate salt form of neratinib, an orally available, quinazoline-based, irreversible inhibitor of both the receptor tyrosine kinases (RTKs) human epidermal growth factor receptor 2 (HER2; ERBB2) and human epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Alternative Names: hki-272 maleate. Nerlynx. Neratinib maleate [MI]. CAS No. 915942-22-2. Product ID: API915942222. Molecular formula: C34H33ClN6O7. Mole weight: 673.1. EINECS: 620-527-5. SMILES: CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C.C(=CC(=O)O)C(=O)O. Category: Anti-Tumor APIs.