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| Product | Description | |
|---|---|---|
| Necrostatin-1 Inactive Control | Necrostatin-1 Inactive Control (Nec-1i) is a cell-permeable demethylated analog of necrostatin-1 (Nec-1), an RIP1 kinase inhibitor. Synonyms: Nec-1i; 5-(Indol-3-ylmethyl)-2-thiohydantoin. Grades: ≥98%. CAS No. 64419-92-7. Molecular formula: C12H11N3OS. Mole weight: 245.3. |  |
| Necrostatin 2 | Necrostatin 2 is a potent necroptosis inhibitor. It is a potent in vitro necroptosis inhibitors and is also efficacious in an animal model of ischemic stroke. Synonyms: Necrostatin 2; Necrostatin-2; Necrostatin2; Nec-2; Nec 2; Nec2; 2,4-Imidazolidinedione, 5-[(7-chloro-1H-indol-3-yl)methyl]-3-methyl-, (5R)-. Grades: >98%. CAS No. 852391-19-6. Molecular formula: C13H12ClN3O2. Mole weight: 277.71. | |
| Necrostatin 2 | Necrostatin 2 is a potent necroptosis inhibitor. EC 50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-α is 0.05 μM. Necrostatin 2 is also a RIPK1 inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 852391-19-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14622. |  |
| Necrostatin 2 racemate | Necrostatin 2 racemate (Nec-1S), the Necrostatin-1 (HY-15760) stable, is a potent and specific RIPK1 inhibitor lacking the IDO-targeting effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Necrostatin 1S; Nec-1S; 7-Cl-O-Nec1. CAS No. 852391-15-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-14622A. | |
| Necrostatin 2 racemate | Necrostatin 2 racemate is the racemate of Necrostatin, which is a potent necroptosis inhibitor. Grades: >98%. CAS No. 852391-15-2. Molecular formula: C13H12ClN3O2. Mole weight: 277.71. | |
| Necrostatin 2 S enantiomer | Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin, which is a potent necroptosis inhibitor. Synonyms: Necrostatin 2 S enantiomer; 852391-20-9; Necrostatin 2 (S enantiomer); Necrostatin 2 S-Enantiomer; (5S)-5-[(7-CHLORO-1H-INDOL-3-YL)METHYL]-3-METHYLIMIDAZOLIDINE-2,4-DIONE; (S)-5-((7-chloro-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione; SCHEMBL859928; CHEMBL365607; CJB39120; HY-14622B; AKOS030526930; CS-1665; 2,4-Imidazolidinedione, 5-[(7-chloro-1H-indol-3-yl)methyl]-3-methyl-, (5S)-; NCGC00390744-01; MS-23944; F84976; A917559. Grades: >98%. CAS No. 852391-20-9. Molecular formula: C13H12ClN3O2. Mole weight: 277.71. | |
| Necrostatin-5 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
| Necrostatin-5 | Necrostatin-5 (Nec-5) is a potent necroptosis inhibitor with an EC50 value of 0.24 μM. Necrostatin-5 also is a RIP1 inhibitor. Necrostatin-5 shows cardioprotective effects. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 337349-54-9. Molecular formula: C19H17N3O2S2. Mole weight: 383.49. Purity: 0.9843. Product ID: ACM337349549. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Necrostatin-5 | Necrostatin-5 is a selective allosteric inhibitor of RIP1 kinase, an enzyme responsible for necroptosis. Synonyms: Nec-5; 2-[[3,4,5,6,7,8-hexahydro-3-(4-methoxyphenyl)-4-oxo[1]benzothieno[2,3-d]pyrimidin-2-yl]thio]-acetonitrile; 3-p-methoxyphenyl-5,6-tetramethylenothieno[2,3-d]pyrimidin-4-one-2-mercaptoethylcyanide. Grades: ≥98%. CAS No. 337349-54-9. Molecular formula: C19H17N3O2S2. Mole weight: 383.5. | |
| Necrostatin-5 (Nec-5, 3-p-Methoxyphenyl-5, 6-tetramethylenothieno [2, 3-d]pyrimidin-4-one-2-mercaptoethylcyanide) | Inhibits non-apoptotic cell death pathway by inhibition of the death domain receptor-associated adaptor kinase RIP1. Three distinct mechanisms appear to be involved in necroptosis, the alternative active cell death pathway: T-loop dependent inhibition by necrostatin-1; partially T-loop independent inhibition by necrostatin-3 and indirect inhibition of RIP1 by necrostatin-5. Group: Biochemicals. Alternative Names: 3-p-Methoxyphenyl-5, 6-tetramethylenothieno [2, 3-d]pyrimidin-4-one-2-mercaptoethylcyanide) . Grades: Highly Purified. CAS No. 337349-54-9. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. |  Worldwide |
| Necrostatin-5 (Nec-5, 3-p-Methoxyphenyl-5, 6-tetra methyl enothienopyrimidin-4-one-2-mercaptoethylcyanide) | Necroptosis inhibitor. Indirect RIP1 kinase inhibitor. Group: Biochemicals. Alternative Names: Nec-5, 3-p-Methoxyphenyl-5, 6-tetra methyl enothienopyrimidin-4-one-2-mercaptoethylcyanide. Grades: Highly Purified. CAS No. 337349-54-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Necrostatin-7 | Necrotatin-7 (Nec-7) is a potent necroptosis inhibitor with an EC 50 of 10.6 μM. Necrotatin-7 does not inhibit recombinant RIP1 kinase [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nec-7. CAS No. 351062-08-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117200. | |
| Necrostatin-7 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| Necrostatin-7 | Necrotatin-7 (Nec-7) is a potent necroptosis inhibitor with an EC50 of 10.6 μM. Necrotatin-7 does not inhibit recombinant RIP1 kinase. Uses: Designed for use in research and industrial production. Additional or Alternative Names: STK763743, necrotatin-7, Necrostatin-7, AC1LOGUN, Nec-7, CHEMBL514242, HMS621M06, MolPort-002-708-930, ZINC20587175, AKOS001738191, A2363/0099838, 5-[3-(4-Fluoro-phenyl)-1H-pyrazol-4-ylmethylene]-2-imino-[2,3]bithiazolyl-4-one, (5Z)-5-[[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene]-2-imino-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-4-one, (5Z)-5-{[3-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene}-2-imino-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-4-one, 351062-08-3, 5-[[3-(4-Fluorophenyl)-1H-pyrazol-4-yl]methylene]-2-imino-3-(2-thiazolyl)-4-thiazolidinone. Product Category: Inhibitors. Appearance: Solid. CAS No. 351062-08-3. Molecular formula: C16H10FN5OS2. Mole weight: 371.41. Purity: 0.96. IUPACName: (5Z)-5-[[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene]-2-imino-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-4-one. Canonical SMILES: C1=CC(=CC=C1C2=C(C=NN2)C=C3C(=O)N(C(=N)S3)C4=NC=CS4)F. Product ID: ACM351062083. Alfa Chemistry ISO 9001:2015 Certified. | |
| Necrostatin-7 (Nec-7) | Necroptosis inhibitor. Does not inhibit RIP1 kinase. Group: Biochemicals. Alternative Names: Nec-7. Grades: Highly Purified. CAS No. 351062-08-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Necrostatin-7 ((Z)-5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one, Nec-7) | A necroptosis inhibitor. The biological activity of necrostatin-7 (Nec-7) is different from that of necrostatin-1 to -5 as Nec-7 does not inhibit RIP1 kinase. Nec-7 may target an additional regulatory molecule in the pathway. Group: Biochemicals. Alternative Names: (Z)-5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one, Nec-7. Grades: Highly Purified. CAS No. 351062-08-3. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Necrosulfonamide | Necrosulfonamide is a pharmacological inhibitor of MLKL with IC50 values of 124 nM in human HT-29, which significantly decreases BV6/DAC-induced cell death in MV4-11 cells. It prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Synonyms: (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide. Grades: ≥98% by HPLC. CAS No. 1360614-48-7. Molecular formula: C18H15N5O6S2. Mole weight: 461.47. | |
| Necrosulfonamide | Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway. Group: Biochemicals. Alternative Names: N-[4-[[ (3-Methoxypyrazinyl) amino]sulfonyl]phenyl]-3- (5-nitro-2-thienyl) -2-propenamide; (E)-N-[4-[N-(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylamide. Grades: Highly Purified. CAS No. 432531-71-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Necrosulfonamide | Necrosulfonamide, a necroptosis and gasdermin D inhibitor, selectively targets (MLKL). Necrosulfonamide prevents the MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors. MLKL is a key substrate of RIP3 in the induction of necrosis[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1360614-48-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100573. | |
| Necrosulfonamide-d4 | Labeled Necrosulfonamide. Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway. Group: Biochemicals. Alternative Names: N-[4-[[ (3-Methoxypyrazinyl) amino]sulfonyl] (phenyl]-d4) -3- (5-nitro-2-thienyl) -2-propenamide; (E)-N-[4-[N-(3-methoxypyrazin-2-yl)sulfamoyl](phenyl-d4)]-3-(5-nitrothiophene-2-yl)acrylamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Necrox-5 (methanesulfonate) | Necrox-5 is a cell permeable necrosis inhibitor with the antioxidant and cardioprotective effects. It localizes mainly in the mitochondria that selectively blocks oxidative stress-induced necrotic cell death (0.1μM NecroX-5 prevented ~50% cell death in H9C2 cells exposed to 400μM t-BuOOH for 2 hours LDH assay used). Necrox-5 was demonstrated that protect cells from oxidative stress, hypoxia, cold shock, CCl4-induced liver injury and chronic liver fibrosis. Uses: A cell permeable necrosis inhibitor with the antioxidant and cardioprotective effects. Synonyms: NecroX-5 mesylate; 5-[(1,1-dioxido-4-thiomorpholinyl)methyl]-2-phenyl-N-[(tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-7-amine dimethanesulfonate; Necrosis Inhibitor 5; 1H-Indol-7-amine, 5-[(1,1-dioxido-4-thiomorpholinyl)methyl]-2-phenyl-N-[(tetrahydro-2H-pyran-4-yl)methyl]-, methanesulfonate (1:2). Grades: ≥98%. CAS No. 1383718-29-3. Molecular formula: C25H31N3O3S.2CH4O3S. Mole weight: 645.81. | |
| Nectaryl | Nectaryl. CAS No. 95962-14-4. VIGON Item # 500924. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, peach cyclopentanone. |  America & Internationally |
| Ned 19 | Ned 19 is a selective membrane-permeant non competitive NAADP antagonist and inhibits NAADP-mediated Ca2+ signaling, with an IC50 of 65 nM[1]. Ned 19 strongly inhibits tumor growth and vascularization as well as lung metastases in mice[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 874374-25-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-103316A. | |
| Nedaplatin | Nedaplatin (NSC 375101D) is a derivative of cisplatin and DNA damage agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 375101D. CAS No. 95734-82-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13700. | |
| Nedaplatin | (Glycolato-o,o')diammineplatinum(II) cis-Diammine(glycolato)platinum(II). Grades: CAS No. 95734-82-0. Product ID: 8-04510. Molecular formula: C2H4N2O3Pt. Mole weight: 299.15. |  |
| Nedaplatin | Nedaplatin is a derivative of cisplatin and DNA damage agent for tumor colony forming units with IC50 of 94 μM. Synonyms: Nedaplatin; 95734-82-0; AquplaNSC 375101Dazane;2-hydroxyacetic acid;platinum. Grades: >98%. CAS No. 95734-82-0. Molecular formula: C2H8N2O3Pt. Mole weight: 303.17. | |
| NEDD4 Active human | recombinant, expressed in baculovirus infected insect cells, ?60% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Ne-Dimethyl-L-lysine hydrochloride | Ne-Dimethyl-L-lysine hydrochloride. Group: Biochemicals. Alternative Names: L-Lys(Me)2-OH·HCl. Grades: Highly Purified. CAS No. 2259-86-1. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. US Biological Life Sciences. | Worldwide |
| Ne-Dimethyl-L-lysine hydrochloride 98+% (NMR) | Ne-Dimethyl-L-lysine hydrochloride 98+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| Nedisertib | Nedisertib (Peposertib) is an orally active selective DNA-dependent protein kinase (DNA-PK) inhibitor with an IC50 value of less than 3 nM. Nedisertib also acts as a modulator of ABCG2, capable of reversing ABCG2-mediated multidrug resistance (MDR), thus providing new strategies for combination therapy. By inhibiting DNA double-strand break repair, Nedisertib can enhance the efficacy of chemotherapy and radiotherapy. Nedisertib exhibits antitumor activity[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Peposertib; M3814. CAS No. 1637542-33-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101570. | |
| Nedizantrep | GDC-6599 is an orally active TRPA1 inhibitor, with IC 50 values of 5.3 nM in humans, 6.6 nM in rats, 9.3 nM in dogs, 7.2 nM in monkeys, and 15 nM in guinea pigs. GDC-6599 can be used in the research of neuropathic pain and respiratory diseases such as asthma and chronic cough [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-6599. CAS No. 2376824-99-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-156684. | |
| Ned-K | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ned-K | Ned-K, a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist, effectively inhibits Ca2+ oscillations induced by simulated ischemia and reperfusion (sIR) in cardiomyocytes. Synonyms: 1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-[3-[[4-(2-cyanophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-, (1R,3S)-; (1R,3S)-1-(3-{[4-(2-Cyanophenyl)-1-piperazinyl]methyl}-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid. CAS No. 2250019-90-8. Molecular formula: C31H31N5O3. Mole weight: 521.61. | |
| Nedocromil | Nedocromil suppresses the action or formation of multiple mediators, including histamine , leukotriene C 4 ( LTC 4 ), and prostaglandin D 2 ( PGD 2 ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: FPL 59002. CAS No. 69049-73-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13448. | |
| Nedocromil | Nedocromil is an inhaled anti-inflammatory agent for the preventive management of asthma. Synonyms: FPL59002; FPL-59002; FPL 59002; Nedocromil; Nedocromilo. Grades: >98%. CAS No. 69049-73-6. Molecular formula: C19H17NO7. Mole weight: 371.34. | |
| Nedocromil sodium | Nedocromil sodium is a mast cell stabilizer that prevents wheezing, shortness of breath, and other breathing problems caused by asthma. Synonyms: 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, sodium salt (1:2); 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic Acid Disodium Salt; Alocril; FPL 59002KP; Nedocromil disodium salt; Rapitil; Tayled; Tilade; Tilarin; 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, disodium salt. Grades: 95%. CAS No. 69049-74-7. Molecular formula: C19H15NNa2O7. Mole weight: 415.30. | |
| Nedocromil sodium | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Needle Mushroom Powder | Needle Mushroom Powder contains a large quantity of a protein, designated Five, which helps to regulate the immune system. Animal testing indicated possible uses for vaccines and cancer immunotherapy. Needle Mushroom Powder also contains flammutoxin, a cytolytic and cardiotoxic protein that may possibly be poorly absorbed orally. Group: Others. Needle Mushroom Powder; Flammulina Velutipes. Cat No: EXTC-074. |  |
| Neem | This product contains essential fatty acids and vitamin E to work double time on hydrating and plumping the skin, for a healthy look and feel. Pack Sizes: 1 kg. Product ID: CDC10-0556. Category: Anti-Acne Ingredients. Product Keywords: Cosmetic Ingredients; Active Ingredients; Anti-Acne Ingredients; Neem; CDC10-0556. |  |
| NEEM OIL* | NEEM OIL*. Uses: Designed for use in research and industrial production. Additional or Alternative Names: clarified;clarifiedhydrophobicextractof;clarifiedhydrophobicextractofneemoil;clarifiedhydrophobicextractofneemoilchemical;clarifiedhydrophobicneemoil;margosaoil;nim-76;nimoil. Product Category: Heterocyclic Organic Compound. CAS No. 8002-65-1. Molecular formula: W99. Product ID: ACM8002651. Alfa Chemistry ISO 9001:2015 Certified. | |
| Nefazodone | Nefazodone is an orally active phenylpiperazine antidepressant. Nefazodone can potently and selectively block postsynaptic 5-HT 2A receptors , and moderately inhibit 5-HT and noradrenaline reuptake. Nefazodone can also relieve the adverse effects of stress on the the immune system of mice. Nefazodone has a high affinity for CYP3A4 isoenzyme, which indicates that it has certain risk of agent-agent interaction [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83366-66-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119209. | |
| NEFAZODONE | Nefazodone is a selective serotonin 5-HT2 receptor antagonist. It is an antidepressant under the development of Bristol-Myers Squibb. Its sale was discontinued in some countries due to the rare incidence of hepatotoxicity. Uses: Antidepressant. Synonyms: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one; 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one; 3H-1,2,4-Triazol-3-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-; BMY-13754; 1-(3-(4-(3-Chlorophenyl)piperazin-1-yl)propyl)-3-ethyl-4-(2-phenoxyethyl)-1H-1,2,4-triazol-5(4H)-one. Grades: 95%. CAS No. 83366-66-9. Molecular formula: C25H32ClN5O2. Mole weight: 470.01. | |
| Nefazodone HCl | Nefazodone hydrochloride is a selective serotonin 5-HT2 receptor antagonist. It is used as an antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants. It is a phenylpiperazin derivative, whose structure is similar to that of some known antidepressants. It was developed by Bristol-Myers Squibb. Uses: Nefazodone hydrochloride is used as an antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants. Synonyms: BMY 13754; BMY13754; BMY-13754; Dutonin; Nefazodone HCl; Rulivan; MJ 13754 1; MJ-13754-1; MJ137541. 3H-1,2,4-Triazol-3-one, 2-3-4-(3-chlorophenyl)-1-piperazinylpropyl-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-, monohydrochloride;Nefazodone HCl;BMY-13754;MJ-13754-1;2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride;2,4-Dihydro-2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-5-ethyl-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride; Serzone; Dutonin; Menfazona. Grades: 95%. CAS No. 82752-99-6. Molecular formula: C25H33Cl2N5O2. Mole weight: 506.46. | |
| Nefazodone hydrochloride | Nefazodone hydrochloride. CAS No: 82752-99-6 |  Sarchem Laboratories New Jersey NJ |
| Nefazodone hydrochloride | Nefazodone hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 82752-99-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Nefazodone hydrochloride | Nefazodone hydrochloride (BMY-13754) is a potent and selective 5HT2A ( K i =5.8 nM) antagonist with moderate inhibition of 5-HT and noradrenaline uptake ( IC 50 of 290 and 300 nM, respectively). Nefazodone hydrochloride is a phenylpiperazine antidepressant with less alpha-adrenergic blocking activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMY-13754; MJ-13754-1. CAS No. 82752-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1396. | |
| Nefazodone, Hydrochloride (2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one, Hydrochloride) | A selective serotonin 5-HT2 receptor antagonist. An antidepressant. Group: Biochemicals. Alternative Names: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one, Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Nefazodone Hydrochloride (5-HT2A Serotonin Receptor Antagonist, Nefazodone, BMY-13754, MJ-13754-1, Serzone) | A potent 5-HT2A receptor antagonist (Kd = 26nM), with moderate affinity for the alpha1-adrenergic receptor (Kd = 48nM) and 5-HT1A receptor (Kd = 80nM). Originally developed as a clinical antidepressant but discontinued in 2004, nefazodone (Serzone) still remains a specific inhibitor of certain serotonergic pathways. Nefazodone also has been reported to induce mitochondrial dysfunction. Group: Biochemicals. Grades: Highly Purified. CAS No. 82752-99-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Nefazodone Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Nefazodone Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Neferine | Neferine is a major bisbenzylisoquinline alkaloid. Neferine strongly inhibits NF-κB activation. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Neferine. CAS No. 2292-16-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0441. | |
| Neferine | Neferine. Group: Biochemicals. Grades: Plant Grade. CAS No. 2292-16-2. Pack Sizes: 20mg. Molecular Formula: C38H44N2O6, Molecular Weight: 624.77. US Biological Life Sciences. | Worldwide |
| Neferine | Neferine is a bis-benzylisoquinoline alkaloid isolated from the green seed embryos Nelumbo Nucifera Gaertn (Lotus) that displays multiple pharmacological activities including anti-tumor, antidepressant-like and antiarrhythmic actions. It potently inhibits proliferation of human osteosarcoma cells while is low-toxic on non-neoplastic human osteoblast cells. It inhibited high glucose-induced endothelial apoptosis via blocking ROS/Akt/NF-κB pathway, which provides the evidence for using Neferine to treat diabetic vasculopathy. Synonyms: 4-[(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)methyl]-2-[[1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methylisoquinolin-7-yl]oxy]phenol; 4''-O-Methylliensinine; Methylliensinine; Phenol,4-[[(1S)-1,2,3,4-tetrahydro-6,7-diMethoxy-2-Methyl-1-isoquinolinyl]Methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-Methoxy-1-[(4-Methoxyphenyl)Methyl]-2-Methyl-7-isoquinolinyl]oxy]-; 4-[[(1R)-6,7-Dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol. Grades: >98%. CAS No. 2292-16-2. Molecular formula: C38H44N2O6. Mole weight: 624.76. | |
| Neferine | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Nef Hck Activation Inhibitor, B9 (Nef Dimerization Blocker, (E)-4-((3-Chlorophenyl)diazenyl)-5-hydroxy-3-(4-nitrophenyl)-1H-pyrazole-1-carbothioamide) | A cell-permeable diphenylpyrazolo compound that disrupts HIV accessary protein Nef dimerization (IC50 = 3uM in HEK293T cells) and prevents Nef-mediated Src family kinase Hck activation (IC50 = 2.8uM) without directly affecting the catalytic activity of c-Src, Hck, Lck, or Lyn. Shown to suppress HIV and SIV viral replication (IC50/strain/culture = 1uM/SIV deltaB670/CEM-174 and <0.3uM/HIV-1 NL4-3/CEM-T4) and infectivity, being ineffective against the replication of Nef-defective HIV-1 mutant. Molecular docking and in vitro binding studies reveal a high-affinity B9-targeting site formed at the Nef dimerization interface and a low-affinity binding site on each Nef monomer at the dimer interface periphery. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O?S, Primary Target: Nef. US Biological Life Sciences. | Worldwide |
| Nefiracetam | Nefiracetam. Group: Biochemicals. Grades: Purified. CAS No. 77191-36-7. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Nefiracetam | Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal system enhancer for Ro 5-4864-induced convulsions. Uses: Neuroprotective agents. Synonyms: Nefiracetam; 77191-36-7; N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide; Translon; DM 9384. Grades: >98%. CAS No. 77191-36-7. Molecular formula: C14H18N2O2. Mole weight: 246.3. | |
| Nefiracetam | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Nefiracetam | Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal systems enhancer for Ro 5-4864-induced convulsions. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DM9384; DZL-221. CAS No. 77191-36-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B0340. | |
| Neflamapimod | Neflamapimod (VX-745) is a potent, blood-brain barrier penetrant, highly selective inhibitor of p38α inhibitor with an IC 50 for p38α of 10 nM and for p38β of 220 nM. Neflamapimod (VX-745) possesses anti-inflammatory activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-745. CAS No. 209410-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10328. | |
| Ne-Fmoc-L-lysine | Ne-Fmoc-L-lysine. Group: Biochemicals. Alternative Names: L-Lys(Fmoc)-OH. Grades: Highly Purified. CAS No. 84624-28-2. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Fmoc-L-lysine 99+% (HPLC) | Ne-Fmoc-L-lysine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Fmoc-L-lysine methyl ester hydrochloride | Ne-Fmoc-L-lysine methyl ester hydrochloride. Group: Biochemicals. Alternative Names: L-Lys(Fmoc)-OMe·HCl. Grades: Highly Purified. CAS No. 201009-98-5. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Fmoc-L-lysine methyl ester hydrochloride 99+% | Ne-Fmoc-L-lysine methyl ester hydrochloride 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Nefopam | Nefopam is a non-opioid non-steroidal centrally acting analgesic. Group: Biochemicals. Grades: Highly Purified. CAS No. 13669-70-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C17H19NO, Molecular Weight: 253.34. US Biological Life Sciences. | Worldwide |
| Nefopam glucuronide | Nefopam glucuronide is a compound, standing as a vital metabolite of Nefopam, a non-opioid analgesic. Synonyms: Nefopam N-b-D glucuronide. Molecular formula: C23H27NO7. Mole weight: 429.46. | |
| Nefopam hydrochloride | Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fenazoxine hydrochloride. CAS No. 23327-57-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B1057. | |
| Nefopam Hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyapi standardspharmaceutical toxicology. Alternative Names: Fenazoxine, Acupan, Nefopam hydrochloride,1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride (1:1), 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride (8CI,9CI), Fenazoxine hydrochloride, R 738, Ajan, (+/-)-Nefopam hydrochloride. | |
| Nefopam Hydrochloride | A cyclized analog of orphenadrine and diphenhydramine; representative of a new class of centrally acting skeletal muscle relaxants, the benzoxazocines. Analgesic; antidepressant. Group: Biochemicals. Alternative Names: 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine Hydrochloride; (+/-)-Nefopam Hydrochloride; Acupan; Ajan; Fenazoxine; Fenazoxine hydrochloride; R 738. Grades: Highly Purified. CAS No. 23327-57-3. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Nefopam Hydrochloride | Nefopam HCl is a centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake.It is widely used, mainly in European countries, for the relief of moderate to severe pain as an alternative to opioid analgesic drugs. Uses: Analgesics, non-narcotic. Synonyms: Nefopam Hydrochloride. Grades: >98%. CAS No. 23327-57-3. Molecular formula: C17H19NO.HCl. Mole weight: 289.8. | |
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