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| Product | Description | |
|---|---|---|
| Nefazodone hydrochloride | Nefazodone hydrochloride (BMY-13754) is a potent and selective 5HT2A ( K i =5.8 nM) antagonist with moderate inhibition of 5-HT and noradrenaline uptake ( IC 50 of 290 and 300 nM, respectively). Nefazodone hydrochloride is a phenylpiperazine antidepressant with less alpha-adrenergic blocking activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMY-13754; MJ-13754-1. CAS No. 82752-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1396. |  |
| Nefazodone, Hydrochloride (2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one, Hydrochloride) | A selective serotonin 5-HT2 receptor antagonist. An antidepressant. Group: Biochemicals. Alternative Names: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one, Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Nefazodone Hydrochloride (5-HT2A Serotonin Receptor Antagonist, Nefazodone, BMY-13754, MJ-13754-1, Serzone) | A potent 5-HT2A receptor antagonist (Kd = 26nM), with moderate affinity for the alpha1-adrenergic receptor (Kd = 48nM) and 5-HT1A receptor (Kd = 80nM). Originally developed as a clinical antidepressant but discontinued in 2004, nefazodone (Serzone) still remains a specific inhibitor of certain serotonergic pathways. Nefazodone also has been reported to induce mitochondrial dysfunction. Group: Biochemicals. Grades: Highly Purified. CAS No. 82752-99-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Neferine | Neferine is a bis-benzylisoquinoline alkaloid isolated from the green seed embryos Nelumbo Nucifera Gaertn (Lotus) that displays multiple pharmacological activities including anti-tumor, antidepressant-like and antiarrhythmic actions. It potently inhibits proliferation of human osteosarcoma cells while is low-toxic on non-neoplastic human osteoblast cells. It inhibited high glucose-induced endothelial apoptosis via blocking ROS/Akt/NF-κB pathway, which provides the evidence for using Neferine to treat diabetic vasculopathy. Synonyms: 4-[(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)methyl]-2-[[1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methylisoquinolin-7-yl]oxy]phenol; 4''-O-Methylliensinine; Methylliensinine; Phenol,4-[[(1S)-1,2,3,4-tetrahydro-6,7-diMethoxy-2-Methyl-1-isoquinolinyl]Methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-Methoxy-1-[(4-Methoxyphenyl)Methyl]-2-Methyl-7-isoquinolinyl]oxy]-; 4-[[(1R)-6,7-Dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol. Grades: >98%. CAS No. 2292-16-2. Molecular formula: C38H44N2O6. Mole weight: 624.76. |  |
| Neferine | Neferine. Group: Biochemicals. Grades: Plant Grade. CAS No. 2292-16-2. Pack Sizes: 20mg. Molecular Formula: C38H44N2O6, Molecular Weight: 624.77. US Biological Life Sciences. | Worldwide |
| Neferine | Neferine is a major bisbenzylisoquinline alkaloid. Neferine strongly inhibits NF-κB activation. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Neferine. CAS No. 2292-16-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0441. | |
| Nef Hck Activation Inhibitor, B9 (Nef Dimerization Blocker, (E)-4-((3-Chlorophenyl)diazenyl)-5-hydroxy-3-(4-nitrophenyl)-1H-pyrazole-1-carbothioamide) | A cell-permeable diphenylpyrazolo compound that disrupts HIV accessary protein Nef dimerization (IC50 = 3uM in HEK293T cells) and prevents Nef-mediated Src family kinase Hck activation (IC50 = 2.8uM) without directly affecting the catalytic activity of c-Src, Hck, Lck, or Lyn. Shown to suppress HIV and SIV viral replication (IC50/strain/culture = 1uM/SIV deltaB670/CEM-174 and <0.3uM/HIV-1 NL4-3/CEM-T4) and infectivity, being ineffective against the replication of Nef-defective HIV-1 mutant. Molecular docking and in vitro binding studies reveal a high-affinity B9-targeting site formed at the Nef dimerization interface and a low-affinity binding site on each Nef monomer at the dimer interface periphery. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O?S, Primary Target: Nef. US Biological Life Sciences. | Worldwide |
| Nefiracetam | Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal systems enhancer for Ro 5-4864-induced convulsions. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DM9384; DZL-221. CAS No. 77191-36-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B0340. | |
| Nefiracetam | Nefiracetam. Group: Biochemicals. Grades: Purified. CAS No. 77191-36-7. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Nefiracetam | Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal system enhancer for Ro 5-4864-induced convulsions. Uses: Neuroprotective agents. Synonyms: Nefiracetam; 77191-36-7; N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide; Translon; DM 9384. Grades: >98%. CAS No. 77191-36-7. Molecular formula: C14H18N2O2. Mole weight: 246.3. | |
| Neflamapimod | Neflamapimod (VX-745) is a potent, blood-brain barrier penetrant, highly selective inhibitor of p38α inhibitor with an IC 50 for p38α of 10 nM and for p38β of 220 nM. Neflamapimod (VX-745) possesses anti-inflammatory activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-745. CAS No. 209410-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10328. | |
| Ne-Fmoc-L-lysine | Ne-Fmoc-L-lysine. Group: Biochemicals. Alternative Names: L-Lys(Fmoc)-OH. Grades: Highly Purified. CAS No. 84624-28-2. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Fmoc-L-lysine 99+% (HPLC) | Ne-Fmoc-L-lysine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Fmoc-L-lysine methyl ester hydrochloride | Ne-Fmoc-L-lysine methyl ester hydrochloride. Group: Biochemicals. Alternative Names: L-Lys(Fmoc)-OMe·HCl. Grades: Highly Purified. CAS No. 201009-98-5. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Ne-Fmoc-L-lysine methyl ester hydrochloride 99+% | Ne-Fmoc-L-lysine methyl ester hydrochloride 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Nefopam | Nefopam is a non-opioid non-steroidal centrally acting analgesic. Group: Biochemicals. Grades: Highly Purified. CAS No. 13669-70-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C17H19NO, Molecular Weight: 253.34. US Biological Life Sciences. | Worldwide |
| Nefopam glucuronide | Nefopam glucuronide is a compound, standing as a vital metabolite of Nefopam, a non-opioid analgesic. Synonyms: Nefopam N-b-D glucuronide. Molecular formula: C23H27NO7. Mole weight: 429.46. | |
| Nefopam hydrochloride | Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fenazoxine hydrochloride. CAS No. 23327-57-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B1057. | |
| Nefopam Hydrochloride | A cyclized analog of orphenadrine and diphenhydramine; representative of a new class of centrally acting skeletal muscle relaxants, the benzoxazocines. Analgesic; antidepressant. Group: Biochemicals. Alternative Names: 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine Hydrochloride; (+/-)-Nefopam Hydrochloride; Acupan; Ajan; Fenazoxine; Fenazoxine hydrochloride; R 738. Grades: Highly Purified. CAS No. 23327-57-3. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Nefopam Hydrochloride | Nefopam HCl is a centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake.It is widely used, mainly in European countries, for the relief of moderate to severe pain as an alternative to opioid analgesic drugs. Uses: Analgesics, non-narcotic. Synonyms: Nefopam Hydrochloride. Grades: >98%. CAS No. 23327-57-3. Molecular formula: C17H19NO.HCl. Mole weight: 289.8. | |
| Nefopam (Hydrochloride) | Nefopam (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine hydrochloride. CAS No. 23327-57-3. Molecular Formula: C17H19NO·HCl. Mole Weight: 289.8. Catalog: APB23327573. |  |
| Nefopam Impurity 10 | Nefopam Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2- ( (2- (hydroxy (phenyl)methyl)benzyl) (methyl)amino)ethanol. CAS No. 60725-36-2. Molecular Formula: C17H21NO2. Mole Weight: 271.16. Catalog: APB60725362. | |
| Nefopam Impurity 12 | Nefopam Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(2-benzoyl-N-methylbenzamido)ethyl 2-benzoylbenzoate. Molecular Formula: C31H25NO5. Mole Weight: 491.17. Catalog: APB01375. | |
| Nefopam Impurity 5 | Nefopam Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2- ( ( (2-hydroxyethyl) (methyl)amino)methyl)phenyl) (phenyl)methanone. CAS No. 76528-10-4. Molecular Formula: C17H19NO2. Mole Weight: 269.34. Catalog: APB76528104. | |
| Nefopam Impurity 6 | Nefopam Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-benzoyl-N-(2-hydroxyethyl)benzamide. CAS No. 108941-80-6. Molecular Formula: C16H15NO3. Mole Weight: 269.11. Catalog: APB108941806. | |
| Nefopam Impurity 7 | Nefopam Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-benzoyl-N-(2-hydroxyethyl)-N-methylbenzamide. CAS No. 24833-47-4. Molecular Formula: C17H17NO3. Mole Weight: 283.12. Catalog: APB24833474. | |
| Nefopam Impurity 8 | Nefopam Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(hydroxy(phenyl)methyl)-N-(2-hydroxyethyl)-N-methylbenzamide. Molecular Formula: C17H19NO3. Mole Weight: 285.14. Catalog: APB01376. | |
| Nefopam N- β-D Glucuronide | Nefopam N- β-D Glucuronide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C17H20ClNO, Molecular Weight: 429.46. US Biological Life Sciences. | Worldwide |
| Nefopam N-Glucuronide (Mixture of Diastereomers) | An impurity of Nefopam, which is a centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake. Synonyms: Nefopam N-β-D Glucuronide. Grades: > 95%. Molecular formula: C23H27NO7. Mole weight: 429.47. | |
| Nefopam N-oxide | Nefopam N-oxide. Group: Biochemicals. Alternative Names: 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine 5-oxide. Grades: Highly Purified. CAS No. 66091-32-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H19NO2. US Biological Life Sciences. | Worldwide |
| Nefopam N-Oxide | Nefopam N-Oxide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine 5-oxide. CAS No. 66091-32-5. Molecular Formula: C17H19NO2. Mole Weight: 269.34. Catalog: APB66091325. | |
| Negamycin | Negamycin is a peptide antibiotic that has broad-spectrum antibacterial activity. Synonyms: L-threo-Hexonic acid, 3,6-diamino-2,3,4,6-tetradeoxy-, 2-(carboxymethyl)-2-methylhydrazide; BRN 4687658. Grades: >98% by HPLC. CAS No. 33404-78-3. Molecular formula: C9H20N4O4. Mole weight: 248.28. | |
| Negative Ion Nanopowder / Nanoparticles | Negative Ion Nanopowder / Nanoparticles. Group: Polymers nano materials. 99%. |  |
| Negative resist developer I | Negative resist developer I. Group: Self assembly and lithography. | |
| Negative resist remover I | Available as part of Negative Photoresist kit 654892. Group: Self assembly and lithography. Pack Sizes: 250 mL in glass bottle. | |
| Negletein | Negletein is a flavonoid with anti-inflammatory and immunomodulatory activities. Synonyms: 5,6-Dihydroxy-7-methoxyflavone; Baicalein-7-methylether; 7-O-Methylbaicalein. Grades: >98%. CAS No. 29550-13-8. Molecular formula: C16H12O5. Mole weight: 284.26. | |
| Negletein | Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 and 10.8 μM, respectively. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 29550-13-8. Molecular formula: C16H12O5. Mole weight: 284.26. Purity: 0.99. Product ID: ACM29550138. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Negsehisandrin G | Negsehisandrin G. Group: Biochemicals. CAS No. 1023744-69-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| n-Eicosane | 100g Pack Size. Group: Building Blocks, Organics. Formula: C20H42. CAS No. 112-95-8. Prepack ID 45515231-100g. Molecular Weight 282.54. See USA prepack pricing. |  |
| Neihulizumab | Neihulizumab (ALTB-168) is an immune checkpoint agonistic antibody that binds to human CD162 (PSGL-1) , leading to downregulation of activated T-cells. Neihulizumab can be uesd for steroid-refractory acute graft-versus-host-disease (SR-aGVHD), psoriasis, psoriatic arthritis and ulcerative colitis research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ALTB-168; Anti-PSGL1/CD162 Reference Antibody (neihulizumab). CAS No. 2158362-38-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99378. | |
| Neihumicin | Neihumicin is produced by the strain of Micromonospora neihuensis Wu, sp. nov. Neihumicin is resistant to beer saccharomyces yeast and Penicillium italium Wehmer, but not to bacteria. Synonyms: Neihumycin; 3,6-Dibenzylidene-2-methoxy-3,6-dihydropyrazin-5-one; NSC617674; (Z,Z)-3,6-Dihydro-5-methoxy-3,6-bis(phenylmethylene)-2(1H)-pyrazinone. CAS No. 111451-12-8. Molecular formula: C19H16N2O2. Mole weight: 304.34. | |
| Neladenoson dalanate | Neladenoson dalanate is a potent adenosine A1 receptor agonist originated by Bayer HealthCare Pharmaceuticals. It is applicated for the treatment of Chronic heart failure. In Apr 2015, Bayer completed the phase II PARSiFAL trial in Chronic heart failure in Germany, Italy, Netherlands and Poland. Uses: Chronic heart failure. Synonyms: BAY 10-67197; BAY 10 67197; BAY-10-67197; BAY1067197; 2-[4-[2-[[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methylsulfanyl]-3,5-dicyano-6-pyrrolidin-1-ylpyridin-4-yl]phenoxy]ethyl (2S)-2-[[(2S)-2-aminopropanoyl]amino]propanoate. Grades: 98%. CAS No. 1239309-58-0. Molecular formula: C35H34ClN7O4S2. Mole weight: 716.27. | |
| Nelarabine | Nelarabine. Group: Biochemicals. Alternative Names: 9- β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine; 506u; Arranon; GW 506U78; MAY; Nelzarabine. Grades: Highly Purified. CAS No. 121032-29-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Nelarabine | Nelarabine acts by inhibiting DNA synthesis and inducing apoptosis in susceptible cells. Nelarabine demonstrated significant antineoplastic activity with acceptable toxicity. Synonyms: 9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine; Arranon; MAY; Nelzarabine; 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine; NSC-686673; (2R,3S,4S,5R)-2-(2-Amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥98% by HPLC. CAS No. 121032-29-9. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| Nelarabine | Nelarabine (506U78) is a nucleoside analogue and can be used for the research of T cell acute lymphoblastic leukemia (T-ALL) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 506U78; GW 506U78; Nelzarabine. CAS No. 121032-29-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13701. | |
| Nelfinavir | Nelfinavir (AG-1341) is a potent and orally bioavailable HIV-1 protease inhibitor ( K i =2 nM) for HIV infection. Nelfinavir is a broad-spectrum, anticancer agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG1341. CAS No. 159989-64-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15287. | |
| Nelfinavir | An HIV-1 protease inhibitor. It inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles. Uses: Hiv protease inhibitors. Synonyms: Viracept; AG 1341; AG-1341; AG1341. Grades: ≥98%. CAS No. 159989-64-7. Molecular formula: C32H45N3O4S. Mole weight: 567.78. | |
| Nelfinavir-d3 | An antiviral. Labeled HIV protease inhibitor. Group: Biochemicals. Alternative Names: (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl thio) butyl ]-3-isoquinolinecarboxamid e ; AG 1341. Grades: Highly Purified. CAS No. 1217629-70-3. Pack Sizes: 1mg. Molecular Formula: C??H??D?N?O?S, Molecular Weight: 570.8. US Biological Life Sciences. | Worldwide |
| Nelfinavir Hydroxy-tert-butylamide | A metabolite of Nelfinavir, which is used as an antiviral. Group: Biochemicals. Grades: Highly Purified. CAS No. 213135-56-9. Pack Sizes: 1mg. Molecular Formula: C32H45N3O5S, Molecular Weight: 583.78. US Biological Life Sciences. | Worldwide |
| Nelfinavir Hydroxy-tert-butylamide | An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-6 protease inhibitor. Synonyms: Nelfinavir Hydroxy-tert-butylamide; (3S,4aS,8aS)-Decahydro-N-(2-hydroxy-1,1-dimethylethyl)-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide. Grades: > 95%. CAS No. 213135-56-9. Molecular formula: C32H45N3O5S. Mole weight: 583.8. | |
| Nelfinavir Mesylate | Nelfinavir Mesylate (AG 1343 Mesylate) is a potent and orally bioavailable HIV-1 protease inhibitor ( K i =2 nM) for HIV infection. Nelfinavir Mesylate (AG 1343 Mesylate) is a broad-spectrum, anticancer agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG 1343 Mesylate. CAS No. 159989-65-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15287A. | |
| Nelfinavir Mesylate | Nelfinaviris a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor. Synonyms: AG-1341; AG 1341; AG1341. Grades: >98%. CAS No. 159989-65-8. Molecular formula: C33H49N3O7S2. Mole weight: 663.89. | |
| Nelfinavir, Mesylate ( (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl thio) butyl ]-3-isoquinolinecarboxamid e , AG-1343) | An antiviral. Group: Biochemicals. Alternative Names: (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl thio) butyl ]-3-isoquinolinecarboxamid e ; AG-1343. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Nelfinavir Mesylate (AG-1343, AG1343, Viracept) | Nelfinavir is a potent competitive inhibitor of the HIV-1 protease. It is reported that it can also inhibit the growth of various cell types and trigger apoptosis. Besides being a protease inhibitor used in the therapeutic agent for acquired immunodeficiency syndrome (AIDS), it is also stimulates autophagy and and exhibits anti-cancer properties. It appears to do by inhibition of the Akt/PKB signaling pathway and activation of endoplasmic reticulum stress with subsequent unfolded protein response (1). Nelfinavir has also been shown to treat SARS-coronavirus (2), and is being tested currently to treat COVID-19. Group: Biochemicals. Alternative Names: AG-1343, AG1343, Viracept; (3S, 4aS, 8aS)-N-tert-butyl-2-[(2R, 3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylsulfanylbutyl]-3, 4, 4a, 5, 6, 7, 8, 8a-octahydro-1H-isoquinoline-3-carboxamide; methanesulfonic acid. Grades: Highly Purified. CAS No. 159989-65-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N?O?S? , Molecular Weight: 663.89. US Biological Life Sciences. | Worldwide |
| Nelfinavir Oxazole Impurity (Impurity A) | An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor. Synonyms: 3-Isoquinolinecarboxam?ide, 2-[(2R)?-2-[(4S)?-4,?5-dihydro-2-(3-hydroxy-2-methylphenyl)?-4-oxazolyl]?-2-hydroxyethyl]?-N-(1,?1-dimethylethyl)?decahydro-, (3S,?4aS,?8aS)?-. Grades: > 95%. CAS No. 188936-07-4. Molecular formula: C26H39N3O4. Mole weight: 457.62. | |
| Nelfinavir Regeoisomer (Impurity D) | An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-4 protease inhibitor. Synonyms: [3S- (3S, 4aS, 8aS, 2'R, 3'R) ]-2-[3'-N-CBz-amino-2'-hydroxy-4'- (phenyl) thio]butyldecahydroisoquinoline-3-N-t-butylcarboxamide; [ (1R, 2R) -3-[ (3S, 4aS, 8aS) -3-[[ (1, 1-Dimethylethyl) amino]carbonyl]octahydro-2 (1H) -isoquinolinyl]-2-hydroxy-1-[ (phenylthio) methyl]propyl]carbamic Acid Phenylmethyl Ester. Grades: > 95%. CAS No. 159878-04-3. Molecular formula: C32H45N3O4S. Mole weight: 567.8. | |
| Nelfinavir Sulfone | Nelfinavir Sulfone is an impurity of Nelfinavir Mesylate. Group: Biochemicals. Alternative Names: (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl sulfonyl ) bu tyl ]-3-isoquinolinecarboxamid e . Grades: Highly Purified. CAS No. 1041389-29-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Nelfinavir Sulfone Impurity (Impurity C) | An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-3 protease inhibitor. Synonyms: Nelfinavir Sulfone; (3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylsulfonyl)butyl]-3-isoquinolinecarboxamide. Grades: > 95%. CAS No. 1041389-29-0. Molecular formula: C32H45N3O6S. Mole weight: 599.8. | |
| Nelfinavir Sulfoxide | Nelfinavir Sulfoxide is an impurity of Nelfinavir Mesylate. Group: Biochemicals. Alternative Names: (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl sulfinyl ) bu tyl ]-3-isoquinolinecarboxamid e . Grades: Highly Purified. CAS No. 1041389-28-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Nelfinavir Sulfoxide Impurity (Impurity B) | An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-2 protease inhibitor. Synonyms: Nelfinavir Sulfoxide; (3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylsulfinyl)butyl]-3-isoquinolinecarboxamide; USP Nelfinavir Related Compound A. Grades: > 95%. CAS No. 1041389-28-9. Molecular formula: C32H45N3O5S. Mole weight: 583.8. | |
| Nelistotug | Nelistotug (GSK 6097608; GSK6097608) is a human IgG1κ antibody targeting CD96 [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2645437-82-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990053. | |
| Nelociguat | Nelociguat is a soluble guanylate cyclase stimulator (sGC stimulator), which is a key enzyme in the nitric oxide (NO) signalling pathway. It is used for the treatment of pulmonary hypertension. It promotes vasodilation and inhibits smooth muscle proliferation, leukocyte recruitment, platelet aggregation and vascular remodelling through a number of downstream mechanisms. It was also used for erectile dysfunction and heart failure. It was developed by Bayer and was in clinic phase 2 trials with no progress. Uses: Nelociguat is used for the treatment of pulmonary hypertension. it was also used for erectile dysfunction and heart failure. Synonyms: BAY60-4552; Methyl [4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate; Carbamic acid, N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-, methyl ester; N-Desmethyl Riociguat. Grades: 98%. CAS No. 625115-52-8. Molecular formula: C19H17FN8O2. Mole weight: 408.39. | |
| Nelonemdaz | Nelonemdaz (Salfaprodil free base) is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz is also a free radical scavenger. Nelonemdaz has excellent neuroprotection against NMDA- and free radical-induced cell death [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Salfaprodil free base; Neu2000. CAS No. 640290-67-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-106408. | |
| Nelonemdaz potassium | Nelonemdaz (Salfaprodil) potassium is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz potassium is also a free radical scavenger. Nelonemdaz potassium has excellent neuroprotection against NMDA- and free radical-induced cell death [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Salfaprodil; Neu2000 potassium. CAS No. 916214-57-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-106408A. | |
| Nelonicline | Nelonicline is an Alpha7 nicotinic acetylcholine receptor(nAChR) agonist and Nicotinic acetylcholine receptor agonist. It plays a key role in inflammatory processes, thought to be involved in the pathophysiology of neuropsychiatric diseases. It is potentially useful for the treatment of Alzheimer's diseases. It may be useful to reduce dyskinesias in both early- and later-stage Parkinson's disease. Uses: Nelonicline is potentially useful for the treatment of alzheimer's diseases. it may be useful to reduce dyskinesias in both early- and later-stage parkinson's disease. Synonyms: ABT-126; ABT126; ABT 126; Nelonicline; (3R,4S,5S)-4-((5-Phenyl-1,3,4-thiadiazol-2-yl)oxy)-1-azaadamantane;ABT-126;ABT126;2-(((3R,4r,5S,7s)-1-azaadamantan-4-yl)oxy)-5-phenyl-1,3,4-thiadiazole. Grades: >98 %. CAS No. 1026134-63-3. Molecular formula: C17H19N3OS. Mole weight: 313.42. | |
| Nelotanserin | Nelotanser is Serotonin 2A receptor inverse agonist. In Aug 2016, Axovant Sciences initiated a phase-II clinical trial in Lewy body disease in USA. Uses: Lewy body disease. Synonyms: 1-[3-(4-bromo-2-methylpyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea;APD125; APD-125; APD 125; Nelotanserin. Grades: 98%. CAS No. 839713-36-9. Molecular formula: C18H15BrF2N4O2. Mole weight: 437.24. | |
| Nelotanserin | Nelotanserin is a potent 5-HT 2A inverse agonist, a moderately potent 5-HT 2C partial inverse agonist and a weak 5-HT 2B inverse agonist, with IC 50 s of 1.7, 79, 791 nM in IP accumulation assays, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APD125. CAS No. 839713-36-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10559. | |
| Nemadectin | The dominant member of a class of milbemycins; shows pronounced nematocidal and insecticidal activity. Synonyms: CL-287088; S541A; LL-F28249 alpha. Grades: >95% by HPLC. CAS No. 102130-84-7. Molecular formula: C36H52O8. Mole weight: 612.79. | |
| Nemadectin | Nemadectin. Group: Biochemicals. Grades: Highly Purified. CAS No. 102130-84-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Nemadectin (Antibiotic S541A, Antibiotic LL-F28249 alpha) | Nemadectin is the dominant member of a class of milbemycins bearing unsaturated longer chain groups at the 25-position. Nemadectin shows pronounced nematocidal and insecticidal activity. Nemadectin is the starting material for moxidectin, a commercial anthelmintic. Group: Biochemicals. Alternative Names: Antibiotic S541A, Antibiotic LL-F28249 alpha. Grades: Highly Purified. CAS No. 102130-84-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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