American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
NECA NECA. Group: Biochemicals. Grades: Purified. CAS No. 35920-39-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
Ne-Carboxymethyl-L-lysine (2-Amino-6-(carboxymethyl-amino)-hexanoic Acid) Atmosphere: Inert gas. Group: Biochemicals. Alternative Names: 2-Amino-6-(carboxymethyl-amino)-hexanoic Acid. Grades: Highly Purified. CAS No. 5746-4-3. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
Worldwide
Ne-Carboxymethyl-L-lysine 98+% Ne-Carboxymethyl-L-lysine 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. USBiological 5
Worldwide
Necitumumab Necitumumab is a human IgG1 monoclonal antibody that binds to EGFR. Necitumumab has been approved for the treatment of squamous NSCLC. Synonyms: Portrazza. CAS No. 906805-06-9. BOC Sciences 11
Necitumumab Necitumumab is a human IgG monoclonal antibody directed against EGFR. Necitumumab can be used for research of NSCLC, colorectal cancer, etc [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 906805-06-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9964. MedChemExpress MCE
Necroptosis-IN-1 Necroptosis-IN-1, an analog of Necrostatin-1, is a potent necroptosis inhibitor. Necroptosis-IN-1 is a RIPK inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1391980-92-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-135826. MedChemExpress MCE
Necroptosis-IN-3 Necroptosis-IN-3 (Compound 69) is a necroptosis inhibitor that inhibits TNF-α induced necroptosis [1]. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1 [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 547698-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148454. MedChemExpress MCE
Necrosis Inhibitor, Necrox-2 ([5-(1,1-Dioxo-thiomorpholin-4-ylmethyl)-2-phenyl-1H-indol-7-yl]-(1-methanesulfonyl-piperidin-4-yl)-amine) A cell-permeable necrosis inhibitor that displays antioxidant property. It localizes mostly in the mitochondria. Selectively blocks oxidative stress-induced necrotic cell death (0.1uM NecroX-2 prevented ~50% cell death in H9C2 cells exposed to 400uM t-BuOOH for 2 hours). Does not protect against staurosporine or etoposide-induced apoptosis. Protects cells against cold shock, hypoxia and oxidative stress in vitro. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. USBiological 4
Worldwide
Necrosis Inhibitor, Necrox-5 ([5-(1,1-Dioxo-thiomorpholin-4-ylmethyl)-2-phenyl-1H-indol-7-yl]-(tetrahydro-pyran-4-ylmethyl)-amine, Dihydrochloride) A cell-permeable necrosis inhibitor that displays antioxidant property. It localizes mostly in the mitochondria. Selectively blocks oxidative stress-induced necrotic cell death (0.1uM NecroX-5 prevented ~50% cell death in H9C2 cells exposed to 400uM t-BuOOH for 2 hours). Does not protect against staurosporine or etoposide-induced apoptosis. Protects cells against cold shock, hypoxia and oxidative stress in vitro, as well as CCl4 -induced acute liver injury and chronic liver fibrosis in rodent models. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. USBiological 4
Worldwide
Necrostatin-1 Competitive indoleamine 2,3-dioxygenase (IDO) inhibitor. Cell permeable, potent and selective necroptosis (a non-apoptotic form of programmed cell death) inhibitor. Showed neuroprotection in a murine model of ischemic brain injury in vivo. Selective and ATP-competitive receptor-interacting protein kinase 1 (RIPK1) inhibitor. Used in inflammatory and degenerative disease models to target RIPK1. Suppresses autophagy and apoptosis in murine brain injury models. Group: Biochemicals. Alternative Names: Nec-1, MTH-Trp, MTH-DL-Tryptophan, Methyl-thiohydantoin DL-tryptophan, 5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone. Grades: Highly Purified. CAS No. 4311-88-0. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?OS. US Biological Life Sciences. USBiological 4
Worldwide
Necrostatin-1 Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM. Synonyms: Necrostatin-1; Necrostatin1; Necrostatin 1; Nec-1; Nec 1; Nec1. Grades: >98%. CAS No. 4311-88-0. Molecular formula: C13H13N3OS. Mole weight: 259.33. BOC Sciences 8
Necrostatin-1 Necrostatin-1 (Nec-1) is a potent and cross the blood-brain barrier necroptosis inhibitor with an EC 50 of 490 nM in Jurkat cells. Necrostatin-1 inhibits RIP1 kinase ( EC 50 =182 nM). Necrostatin-1 is also an IDO inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nec-1. CAS No. 4311-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15760. MedChemExpress MCE
Necrostatin-1 (5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone, Methylthiohydantoin-DL-tryptophan, Nec-1) Inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in the activation of necroptosis (EC50 = 180nM). Group: Biochemicals. Alternative Names: 5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone; 5-(Indol-3-ylmethyl)-3-methyl-2-thiohydantoin; Nec 1. Grades: Highly Purified. CAS No. 4311-88-0. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. USBiological 3
Worldwide
Necrostatin-1 (inactive control) Necrostatin-1 (Nec-1) (inactive control) is an inactive analog of Necrostatin-1 (HY-15760). Necrostatin-1 is a potent necroptosis inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nec-1 (inactive control). CAS No. 64419-92-7. Pack Sizes: 1 mg. Product ID: HY-121954. MedChemExpress MCE
Necrostatin-1 Inactive Control Necrostatin-1 Inactive Control (Nec-1i) is a cell-permeable demethylated analog of necrostatin-1 (Nec-1), an RIP1 kinase inhibitor. Synonyms: Nec-1i; 5-(Indol-3-ylmethyl)-2-thiohydantoin. Grades: ≥98%. CAS No. 64419-92-7. Molecular formula: C12H11N3OS. Mole weight: 245.3. BOC Sciences 9
Necrostatin 2 Necrostatin 2 is a potent necroptosis inhibitor. EC 50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-α is 0.05 μM. Necrostatin 2 is also a RIPK1 inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 852391-19-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14622. MedChemExpress MCE
Necrostatin 2 Necrostatin 2 is a potent necroptosis inhibitor. It is a potent in vitro necroptosis inhibitors and is also efficacious in an animal model of ischemic stroke. Synonyms: Necrostatin 2; Necrostatin-2; Necrostatin2; Nec-2; Nec 2; Nec2; 2,4-Imidazolidinedione, 5-[(7-chloro-1H-indol-3-yl)methyl]-3-methyl-, (5R)-. Grades: >98%. CAS No. 852391-19-6. Molecular formula: C13H12ClN3O2. Mole weight: 277.71. BOC Sciences 9
Necrostatin 2 racemate Necrostatin 2 racemate (Nec-1S), the Necrostatin-1 (HY-15760) stable, is a potent and specific RIPK1 inhibitor lacking the IDO-targeting effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Necrostatin 1S; Nec-1S; 7-Cl-O-Nec1. CAS No. 852391-15-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-14622A. MedChemExpress MCE
Necrostatin 2 racemate Necrostatin 2 racemate is the racemate of Necrostatin, which is a potent necroptosis inhibitor. Grades: >98%. CAS No. 852391-15-2. Molecular formula: C13H12ClN3O2. Mole weight: 277.71. BOC Sciences 9
Necrostatin 2 S enantiomer Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin, which is a potent necroptosis inhibitor. Synonyms: Necrostatin 2 S enantiomer; 852391-20-9; Necrostatin 2 (S enantiomer); Necrostatin 2 S-Enantiomer; (5S)-5-[(7-CHLORO-1H-INDOL-3-YL)METHYL]-3-METHYLIMIDAZOLIDINE-2,4-DIONE; (S)-5-((7-chloro-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione; SCHEMBL859928; CHEMBL365607; CJB39120; HY-14622B; AKOS030526930; CS-1665; 2,4-Imidazolidinedione, 5-[(7-chloro-1H-indol-3-yl)methyl]-3-methyl-, (5S)-; NCGC00390744-01; MS-23944; F84976; A917559. Grades: >98%. CAS No. 852391-20-9. Molecular formula: C13H12ClN3O2. Mole weight: 277.71. BOC Sciences 9
Necrostatin-5 Necrostatin-5 (Nec-5) is a potent necroptosis inhibitor with an EC50 value of 0.24 μM. Necrostatin-5 also is a RIP1 inhibitor. Necrostatin-5 shows cardioprotective effects. Group: Inhibitors. CAS No. 337349-54-9. Molecular formula: C19H17N3O2S2. Mole weight: 383.49. Purity: 0.9843. Catalog: ACM337349549. Alfa Chemistry.
Necrostatin-5 Necrostatin-5 is a selective allosteric inhibitor of RIP1 kinase, an enzyme responsible for necroptosis. Synonyms: Nec-5; 2-[[3,4,5,6,7,8-hexahydro-3-(4-methoxyphenyl)-4-oxo[1]benzothieno[2,3-d]pyrimidin-2-yl]thio]-acetonitrile; 3-p-methoxyphenyl-5,6-tetramethylenothieno[2,3-d]pyrimidin-4-one-2-mercaptoethylcyanide. Grades: ≥98%. CAS No. 337349-54-9. Molecular formula: C19H17N3O2S2. Mole weight: 383.5. BOC Sciences 9
Necrostatin-5 (Nec-5, 3-p-Methoxyphenyl-5, 6-tetramethylenothieno [2, 3-d]pyrimidin-4-one-2-mercaptoethylcyanide) Inhibits non-apoptotic cell death pathway by inhibition of the death domain receptor-associated adaptor kinase RIP1. Three distinct mechanisms appear to be involved in necroptosis, the alternative active cell death pathway: T-loop dependent inhibition by necrostatin-1; partially T-loop independent inhibition by necrostatin-3 and indirect inhibition of RIP1 by necrostatin-5. Group: Biochemicals. Alternative Names: 3-p-Methoxyphenyl-5, 6-tetramethylenothieno [2, 3-d]pyrimidin-4-one-2-mercaptoethylcyanide) . Grades: Highly Purified. CAS No. 337349-54-9. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. USBiological 1
Worldwide
Necrostatin-5 (Nec-5, 3-p-Methoxyphenyl-5, 6-tetra methyl enothienopyrimidin-4-one-2-mercaptoethylcyanide) Necroptosis inhibitor. Indirect RIP1 kinase inhibitor. Group: Biochemicals. Alternative Names: Nec-5, 3-p-Methoxyphenyl-5, 6-tetra methyl enothienopyrimidin-4-one-2-mercaptoethylcyanide. Grades: Highly Purified. CAS No. 337349-54-9. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 3
Worldwide
Necrostatin-7 Necrotatin-7 (Nec-7) is a potent necroptosis inhibitor with an EC 50 of 10.6 μM. Necrotatin-7 does not inhibit recombinant RIP1 kinase [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nec-7. CAS No. 351062-08-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117200. MedChemExpress MCE
Necrostatin-7 Necrotatin-7 (Nec-7) is a potent necroptosis inhibitor with an EC50 of 10.6 μM. Necrotatin-7 does not inhibit recombinant RIP1 kinase. Group: Inhibitors. Alternative Names: STK763743, necrotatin-7, Necrostatin-7, AC1LOGUN, Nec-7, CHEMBL514242, HMS621M06, MolPort-002-708-930, ZINC20587175, AKOS001738191, A2363/0099838, 5-[3-(4-Fluoro-phenyl)-1H-pyrazol-4-ylmethylene]-2-imino-[2,3]bithiazolyl-4-one, (5Z)-5-[[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene]-2-imino-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-4-one, (5Z)-5-{[3-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene}-2-imino-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-4-one, 351062-08-3, 5-[[3-(4-Fluorophenyl)-1H-pyrazol-4-yl]methylene]-2-imino-3-(2-thiazolyl)-4-thiazolidinone. CAS No. 351062-08-3. Molecular formula: C16H10FN5OS2. Mole weight: 371.41. Appearance: Solid. Purity: 0.96. IUPACName: (5Z)-5-[[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene]-2-imino-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-4-one. Canonical SMILES: C1=CC (=CC=C1C2=C (C=NN2)C=C3C (=O)N (C (=N)S3)C4=NC=CS4)F. Catalog: ACM351062083. Alfa Chemistry.
Necrostatin-7 (Nec-7) Necroptosis inhibitor. Does not inhibit RIP1 kinase. Group: Biochemicals. Alternative Names: Nec-7. Grades: Highly Purified. CAS No. 351062-08-3. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 3
Worldwide
Necrostatin-7 ((Z)-5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one, Nec-7) A necroptosis inhibitor. The biological activity of necrostatin-7 (Nec-7) is different from that of necrostatin-1 to -5 as Nec-7 does not inhibit RIP1 kinase. Nec-7 may target an additional regulatory molecule in the pathway. Group: Biochemicals. Alternative Names: (Z)-5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one, Nec-7. Grades: Highly Purified. CAS No. 351062-08-3. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. USBiological 3
Worldwide
Necrosulfonamide Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway. Group: Biochemicals. Alternative Names: N-[4-[[ (3-Methoxypyrazinyl) amino]sulfonyl]phenyl]-3- (5-nitro-2-thienyl) -2-propenamide; (E)-N-[4-[N-(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylamide. Grades: Highly Purified. CAS No. 432531-71-0. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
Necrosulfonamide Necrosulfonamide is a pharmacological inhibitor of MLKL with IC50 values of 124 nM in human HT-29, which significantly decreases BV6/DAC-induced cell death in MV4-11 cells. It prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Synonyms: (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide. Grades: ≥98% by HPLC. CAS No. 1360614-48-7. Molecular formula: C18H15N5O6S2. Mole weight: 461.47. BOC Sciences 9
Necrosulfonamide-d4 Labeled Necrosulfonamide. Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway. Group: Biochemicals. Alternative Names: N-[4-[[ (3-Methoxypyrazinyl) amino]sulfonyl] (phenyl]-d4) -3- (5-nitro-2-thienyl) -2-propenamide; (E)-N-[4-[N-(3-methoxypyrazin-2-yl)sulfamoyl](phenyl-d4)]-3-(5-nitrothiophene-2-yl)acrylamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
Necrox-5 (methanesulfonate) Necrox-5 is a cell permeable necrosis inhibitor with the antioxidant and cardioprotective effects. It localizes mainly in the mitochondria that selectively blocks oxidative stress-induced necrotic cell death (0.1μM NecroX™-5 prevented ~50% cell death in H9C2 cells exposed to 400μM t-BuOOH for 2 hours LDH assay used). Necrox-5 was demonstrated that protect cells from oxidative stress, hypoxia, cold shock, CCl4-induced liver injury and chronic liver fibrosis. Uses: A cell permeable necrosis inhibitor with the antioxidant and cardioprotective effects. Synonyms: NecroX-5 mesylate; 5-[(1,1-dioxido-4-thiomorpholinyl)methyl]-2-phenyl-N-[(tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-7-amine dimethanesulfonate; Necrosis Inhibitor 5; 1H-Indol-7-amine, 5-[(1,1-dioxido-4-thiomorpholinyl)methyl]-2-phenyl-N-[(tetrahydro-2H-pyran-4-yl)methyl]-, methanesulfonate (1:2). Grades: ≥98%. CAS No. 1383718-29-3. Molecular formula: C25H31N3O3S.2CH4O3S. Mole weight: 645.81. BOC Sciences 11
Nectaryl Nectaryl. CAS No. 95962-14-4. VIGON Item # 500924. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, peach cyclopentanone. Vigon
America & Internationally
Nedaplatin Nedaplatin (NSC 375101D) is a derivative of cisplatin and DNA damage agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 375101D. CAS No. 95734-82-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13700. MedChemExpress MCE
Nedaplatin Nedaplatin is a derivative of cisplatin and DNA damage agent for tumor colony forming units with IC50 of 94 μM. Synonyms: Nedaplatin; 95734-82-0; AquplaNSC 375101Dazane;2-hydroxyacetic acid;platinum. Grades: >98%. CAS No. 95734-82-0. Molecular formula: C2H8N2O3Pt. Mole weight: 303.17. BOC Sciences 9
Ne-Dimethyl-L-lysine hydrochloride Ne-Dimethyl-L-lysine hydrochloride. Group: Biochemicals. Alternative Names: L-Lys(Me)2-OH·HCl. Grades: Highly Purified. CAS No. 2259-86-1. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. US Biological Life Sciences. USBiological 8
Worldwide
Ne-Dimethyl-L-lysine hydrochloride 98+% (NMR) Ne-Dimethyl-L-lysine hydrochloride 98+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences. USBiological 5
Worldwide
Nedizantrep GDC-6599 is an orally active TRPA1 inhibitor, with IC 50 values of 5.3 nM in humans, 6.6 nM in rats, 9.3 nM in dogs, 7.2 nM in monkeys, and 15 nM in guinea pigs. GDC-6599 can be used in the research of neuropathic pain and respiratory diseases such as asthma and chronic cough [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-6599. CAS No. 2376824-99-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-156684. MedChemExpress MCE
Ned-K Ned-K, a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist, effectively inhibits Ca2+ oscillations induced by simulated ischemia and reperfusion (sIR) in cardiomyocytes. Synonyms: 1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-[3-[[4-(2-cyanophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-, (1R,3S)-; (1R,3S)-1-(3-{[4-(2-Cyanophenyl)-1-piperazinyl]methyl}-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid. CAS No. 2250019-90-8. Molecular formula: C31H31N5O3. Mole weight: 521.61. BOC Sciences 10
Nedocromil Nedocromil is an inhaled anti-inflammatory agent for the preventive management of asthma. Synonyms: FPL59002; FPL-59002; FPL 59002; Nedocromil; Nedocromilo. Grades: >98%. CAS No. 69049-73-6. Molecular formula: C19H17NO7. Mole weight: 371.34. BOC Sciences 9
Nedocromil Nedocromil suppresses the action or formation of multiple mediators, including histamine , leukotriene C 4 ( LTC 4 ), and prostaglandin D 2 ( PGD 2 ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: FPL 59002. CAS No. 69049-73-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13448. MedChemExpress MCE
Nedocromil sodium Nedocromil sodium is a mast cell stabilizer that prevents wheezing, shortness of breath, and other breathing problems caused by asthma. Synonyms: 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, sodium salt (1:2); 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic Acid Disodium Salt; Alocril; FPL 59002KP; Nedocromil disodium salt; Rapitil; Tayled; Tilade; Tilarin; 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, disodium salt. Grades: 95%. CAS No. 69049-74-7. Molecular formula: C19H15NNa2O7. Mole weight: 415.30. BOC Sciences 9
Needle Mushroom Powder Needle Mushroom Powder contains a large quantity of a protein, designated Five, which helps to regulate the immune system. Animal testing indicated possible uses for vaccines and cancer immunotherapy. Needle Mushroom Powder also contains flammutoxin, a cytolytic and cardiotoxic protein that may possibly be poorly absorbed orally. Group: Others. Needle Mushroom Powder; Flammulina Velutipes. Cat No: EXTC-074. Creative Enzymes
Neem This product contains essential fatty acids and vitamin E to work double time on hydrating and plumping the skin, for a healthy look and feel. Pack Sizes: 1 kg. Product ID: CDC10-0556. Category: Anti-Acne Ingredients. Product Keywords: Cosmetic Ingredients; Active Ingredients; Anti-Acne Ingredients; Neem; CDC10-0556. CD Formulation
Neem Extract Extract obtained from Melia Azadirachta (Neem) peel and fruit. Contains 20% extract dissolved in water and glycerin. Has good moisturizing, humectant and soothing properties. Uses: Anti-aging and moisturizing creams, lotions and serums. after-sun lotions, dry skin products. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 90063-92-6 / 122-99-6. Appearance: Medium to dark amber liquid, characteristic odor. Catalog: CI-SC-0909. Alfa Chemistry.
Neem Extract in Glycerin Extract obtained from Melia Azadirachta (Neem) peel and fruit. Contains 20% extract dissolved in glycerin. Has good moisturizing, humectant and soothing properties. Uses: Anti-aging and moisturizing creams, lotions and serums. after-sun lotions, dry skin products. Group: Skin actives. CAS No. 56-81-5/90063-92-6. Appearance: Light yellow to amber viscous liquid. Catalog: CI-SC-0710. Alfa Chemistry.
Nefazodone Nefazodone is an orally active phenylpiperazine antidepressant. Nefazodone can potently and selectively block postsynaptic 5-HT 2A receptors , and moderately inhibit 5-HT and noradrenaline reuptake. Nefazodone can also relieve the adverse effects of stress on the the immune system of mice. Nefazodone has a high affinity for CYP3A4 isoenzyme, which indicates that it has certain risk of agent-agent interaction [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83366-66-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119209. MedChemExpress MCE
NEFAZODONE Nefazodone is a selective serotonin 5-HT2 receptor antagonist. It is an antidepressant under the development of Bristol-Myers Squibb. Its sale was discontinued in some countries due to the rare incidence of hepatotoxicity. Uses: Antidepressant. Synonyms: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one; 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one; 3H-1,2,4-Triazol-3-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-; BMY-13754; 1-(3-(4-(3-Chlorophenyl)piperazin-1-yl)propyl)-3-ethyl-4-(2-phenoxyethyl)-1H-1,2,4-triazol-5(4H)-one. Grades: 95%. CAS No. 83366-66-9. Molecular formula: C25H32ClN5O2. Mole weight: 470.01. BOC Sciences 10
Nefazodone HCl Nefazodone hydrochloride is a selective serotonin 5-HT2 receptor antagonist. It is used as an antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants. It is a phenylpiperazin derivative, whose structure is similar to that of some known antidepressants. It was developed by Bristol-Myers Squibb. Uses: Nefazodone hydrochloride is used as an antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants. Synonyms: BMY 13754; BMY13754; BMY-13754; Dutonin; Nefazodone HCl; Rulivan; MJ 13754 1; MJ-13754-1; MJ137541. 3H-1,2,4-Triazol-3-one, 2-3-4-(3-chlorophenyl)-1-piperazinylpropyl-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-, monohydrochloride;Nefazodone HCl;BMY-13754;MJ-13754-1;2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride;2,4-Dihydro-2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-5-ethyl-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride; Serzone; Dutonin; Menfazona. Grades: 95%. CAS No. 82752-99-6. Molecular formula: C25H33Cl2N5O2. Mole weight: 506.46. BOC Sciences 6
Nefazodone hydrochloride Nefazodone hydrochloride. CAS No: 82752-99-6 Sarchem Laboratories
Sarchem Laboratories New Jersey NJ
Nefazodone hydrochloride Nefazodone hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 82752-99-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Nefazodone hydrochloride Nefazodone hydrochloride (BMY-13754) is a potent and selective 5HT2A ( K i =5.8 nM) antagonist with moderate inhibition of 5-HT and noradrenaline uptake ( IC 50 of 290 and 300 nM, respectively). Nefazodone hydrochloride is a phenylpiperazine antidepressant with less alpha-adrenergic blocking activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMY-13754; MJ-13754-1. CAS No. 82752-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1396. MedChemExpress MCE
Nefazodone, Hydrochloride (2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one, Hydrochloride) A selective serotonin 5-HT2 receptor antagonist. An antidepressant. Group: Biochemicals. Alternative Names: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one, Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 1
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Nefazodone Hydrochloride (5-HT2A Serotonin Receptor Antagonist, Nefazodone, BMY-13754, MJ-13754-1, Serzone) A potent 5-HT2A receptor antagonist (Kd = 26nM), with moderate affinity for the alpha1-adrenergic receptor (Kd = 48nM) and 5-HT1A receptor (Kd = 80nM). Originally developed as a clinical antidepressant but discontinued in 2004, nefazodone (Serzone) still remains a specific inhibitor of certain serotonergic pathways. Nefazodone also has been reported to induce mitochondrial dysfunction. Group: Biochemicals. Grades: Highly Purified. CAS No. 82752-99-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
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Neferine Neferine is a major bisbenzylisoquinline alkaloid. Neferine strongly inhibits NF-κB activation. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Neferine. CAS No. 2292-16-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0441. MedChemExpress MCE
Neferine Neferine. Group: Biochemicals. Grades: Plant Grade. CAS No. 2292-16-2. Pack Sizes: 20mg. Molecular Formula: C38H44N2O6, Molecular Weight: 624.77. US Biological Life Sciences. USBiological 9
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Neferine Neferine is a bis-benzylisoquinoline alkaloid isolated from the green seed embryos Nelumbo Nucifera Gaertn (Lotus) that displays multiple pharmacological activities including anti-tumor, antidepressant-like and antiarrhythmic actions. It potently inhibits proliferation of human osteosarcoma cells while is low-toxic on non-neoplastic human osteoblast cells. It inhibited high glucose-induced endothelial apoptosis via blocking ROS/Akt/NF-κB pathway, which provides the evidence for using Neferine to treat diabetic vasculopathy. Synonyms: 4-[(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)methyl]-2-[[1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methylisoquinolin-7-yl]oxy]phenol; 4''-O-Methylliensinine; Methylliensinine; Phenol,4-[[(1S)-1,2,3,4-tetrahydro-6,7-diMethoxy-2-Methyl-1-isoquinolinyl]Methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-Methoxy-1-[(4-Methoxyphenyl)Methyl]-2-Methyl-7-isoquinolinyl]oxy]-; 4-[[(1R)-6,7-Dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol. Grades: >98%. CAS No. 2292-16-2. Molecular formula: C38H44N2O6. Mole weight: 624.76. BOC Sciences 9
Nef Hck Activation Inhibitor, B9 (Nef Dimerization Blocker, (E)-4-((3-Chlorophenyl)diazenyl)-5-hydroxy-3-(4-nitrophenyl)-1H-pyrazole-1-carbothioamide) A cell-permeable diphenylpyrazolo compound that disrupts HIV accessary protein Nef dimerization (IC50 = 3uM in HEK293T cells) and prevents Nef-mediated Src family kinase Hck activation (IC50 = 2.8uM) without directly affecting the catalytic activity of c-Src, Hck, Lck, or Lyn. Shown to suppress HIV and SIV viral replication (IC50/strain/culture = 1uM/SIV deltaB670/CEM-174 and <0.3uM/HIV-1 NL4-3/CEM-T4) and infectivity, being ineffective against the replication of Nef-defective HIV-1 mutant. Molecular docking and in vitro binding studies reveal a high-affinity B9-targeting site formed at the Nef dimerization interface and a low-affinity binding site on each Nef monomer at the dimer interface periphery. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O?S, Primary Target: Nef. US Biological Life Sciences. USBiological 4
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Nefiracetam Nefiracetam. Group: Biochemicals. Grades: Purified. CAS No. 77191-36-7. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 5
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Nefiracetam Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal system enhancer for Ro 5-4864-induced convulsions. Uses: Neuroprotective agents. Synonyms: Nefiracetam; 77191-36-7; N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide; Translon; DM 9384. Grades: >98%. CAS No. 77191-36-7. Molecular formula: C14H18N2O2. Mole weight: 246.3. BOC Sciences 8
Nefiracetam Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal systems enhancer for Ro 5-4864-induced convulsions. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DM9384; DZL-221. CAS No. 77191-36-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B0340. MedChemExpress MCE
Neflamapimod Neflamapimod (VX-745) is a potent, blood-brain barrier penetrant, highly selective inhibitor of p38α inhibitor with an IC 50 for p38α of 10 nM and for p38β of 220 nM. Neflamapimod (VX-745) possesses anti-inflammatory activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-745. CAS No. 209410-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10328. MedChemExpress MCE
Ne-Fmoc-L-lysine Ne-Fmoc-L-lysine. Group: Biochemicals. Alternative Names: L-Lys(Fmoc)-OH. Grades: Highly Purified. CAS No. 84624-28-2. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences. USBiological 8
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Ne-Fmoc-L-lysine 99+% (HPLC) Ne-Fmoc-L-lysine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. USBiological 5
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Ne-Fmoc-L-lysine methyl ester hydrochloride Ne-Fmoc-L-lysine methyl ester hydrochloride. Group: Biochemicals. Alternative Names: L-Lys(Fmoc)-OMe·HCl. Grades: Highly Purified. CAS No. 201009-98-5. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences. USBiological 8
Worldwide
Ne-Fmoc-L-lysine methyl ester hydrochloride 99+% Ne-Fmoc-L-lysine methyl ester hydrochloride 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. USBiological 5
Worldwide
Nefopam Nefopam is a non-opioid non-steroidal centrally acting analgesic. Group: Biochemicals. Grades: Highly Purified. CAS No. 13669-70-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C17H19NO, Molecular Weight: 253.34. US Biological Life Sciences. USBiological 1
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Nefopam glucuronide Nefopam glucuronide is a compound, standing as a vital metabolite of Nefopam, a non-opioid analgesic. Synonyms: Nefopam N-b-D glucuronide. Molecular formula: C23H27NO7. Mole weight: 429.46. BOC Sciences 11
Nefopam hydrochloride Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fenazoxine hydrochloride. CAS No. 23327-57-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B1057. MedChemExpress MCE
Nefopam Hydrochloride Nefopam HCl is a centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake.It is widely used, mainly in European countries, for the relief of moderate to severe pain as an alternative to opioid analgesic drugs. Uses: Analgesics, non-narcotic. Synonyms: Nefopam Hydrochloride. Grades: >98%. CAS No. 23327-57-3. Molecular formula: C17H19NO.HCl. Mole weight: 289.8. BOC Sciences

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