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Nigrocin-6N protein precursor, partial is an antimicrobial peptide found in Pelophylax nigromaculatus (Black-spotted frog), and has antimicrobial activity. Synonyms: Ile-Pro-Phe-Val-Ala-Ser-Val-Ala-Ala-Glu-Met-Met-His-His-Val-Tyr-Cys-Ala-Ala-Ser-Lys-Arg-Cys (Disulfide bridge: Cys17-Cys23). Grade: ≥97%.
Nigrocin-OG13
Nigrocin-OG13 is an antimicrobial peptide found in Odorrana grahami (Yunnanfu frog, Rana grahami), and has antibacterial and antifungal activity. Synonyms: Gly-Leu-Leu-Ser-Gly-Ile-Leu-Gly-Ala-Gly-Lys-His-Ile-Val-Cys-Gly-Leu-Ser-Gly-Leu-Lys. Grade: ≥97%. Molecular formula: C89H157N25O24S. Mole weight: 1993.45.
Nigrocin-OG21
Nigrocin-OG21 is an antimicrobial peptide found in Odorrana grahami (Yunnanfu frog, Rana grahami), and has antibacterial and antifungal activity. Synonyms: Gly-Leu-Leu-Ser-Gly-Val-Leu-Gly-Val-Gly-Lys-Lys-Val-Asp-Cys-Gly-Leu-Ser-Gly-Leu-Cys (Disulfide bridge: Cys15-Cys21). Grade: ≥97%. Molecular formula: C85H149N23O26S2. Mole weight: 1973.38.
Nigrocin-OG4
Nigrocin-OG4 is an antimicrobial peptide found in Odorrana grahami (Yunnanfu frog, Rana grahami), and has antibacterial and antifungal activity. Synonyms: Gly-Leu-Leu-Ser-Gly-Ile-Leu-Gly-Ala-Gly-Lys-His-Ile-Ile-Cys-Gly-Leu-Ser-Gly-Leu-Cys (Disulfide bridge: Cys15-Cys21). Grade: ≥96%. Molecular formula: C87H150N24O24S2. Mole weight: 1980.42.
Nigrocin-OG5
Nigrocin-OG5 is an antimicrobial peptide found in Odorrana grahami (Yunnanfu frog, Rana grahami), and has antibacterial and antifungal activity. Synonyms: Gly-Leu-Leu-Ser-Gly-Ile-Leu-Gly-Ala-Gly-Lys-Gln-Lys-Val-Cys-Gly-Leu-Ser-Gly-Leu-Cys (Disulfide bridge: Cys15-Cys21). Grade: ≥96%. Molecular formula: C85H150N24O25S2. Mole weight: 1972.40.
Nigrosin, 5% Aqueous, Laboratory Grade, 100 mL
Notes: Water-soluble stain. Storage Code: Green; general chemical storage. Group: chem-category biological stains. Grades: chem-grade laboratory. CAS No. 8005-03-6. Product ID: 877363. -- SOLD FOR EDUCATIONAL USE ONLY --
Nigrosin, 5% Aqueous, Laboratory Grade 500 mL
Notes: Water-soluble stain. Storage Code: Green; general chemical storage. Group: chem-category biological stains. Grades: chem-grade laboratory. CAS No. 8005-03-6. Product ID: 877365. -- SOLD FOR EDUCATIONAL USE ONLY --
Nigrosine
Nigrosine. Market: Mining. PK Chem Industries: We supply chemicals related to Cosmetic, Personal Care, Food, Pharmaceutical, Feed, Agriculture and Mining Industries.
Nigrosine (C.I. 50420) (Acid Black 2)
100g Pack Size. Group: Stains & Indicators. Formula: N/A. CAS No. 8005-3-6. Prepack ID 20049825-100g. See USA prepack pricing.
Nigrosin-MG1 antimicrobial peptide precursor
Nigrosin-MG1 antimicrobial peptide precursor is an antimicrobial peptide found in Odorrana margaretae (Chinese frog), and has antimicrobial activity. Synonyms: Thr-Ser-Lys-Lys-Ser-Met-Leu-Leu-Leu-Phe-Phe-Leu-Gly-Thr-Ile-Ser-Leu-Ser-Leu-Cys. Grade: ≥96%. Molecular formula: C102H172N22O27S2. Mole weight: 2202.75.
Nigrosin-OG10 antimicrobial peptide
Nigrosin-OG10 antimicrobial peptide is an antimicrobial peptide found in Odorrana grahami (Yunnanfu frog, Rana grahami), and has antimicrobial activity. Synonyms: Gly-Leu-Leu-Ser-Gly-Ile-Leu-Gly-Ala-Gly-Lys-Asn-Ile-Val-Cys-Gly-Leu-Ser-Gly-Leu-Leu-Lys-Leu-Glu-Ser-Glu-Ile-Ile. Grade: ≥96%. Molecular formula: C124H219N31O37S. Mole weight: 2768.36.
Nigrosin-OG13 antimicrobial peptide
Nigrosin-OG13 antimicrobial peptide is an antimicrobial peptide found in Odorrana grahami (Yunnanfu frog, Rana grahami), and has antibacterial and antifungal activity. Synonyms: Gly-Leu-Leu-Ser-Gly-Ile-Leu-Gly-Ala-Gly-Lys-His-Ile-Val-Cys-Gly-Leu-Ser-Gly-Leu-Arg; Nigrosin-OG13. Grade: ≥97%. Molecular formula: C89H157N27O24S. Mole weight: 2021.45.
Nigrosin-OG21 antimicrobial peptide
It is an antimicrobial peptide found in Odorrana grahami (Yunnanfu frog, Rana grahami), and has antibacterial and antifungal activity. Synonyms: Gly-Leu-Leu-Ser-Gly-Val-Leu-Gly-Val-Gly-Lys-Lys-Val-Leu-Cys-Gly-Leu-Ser-Gly-Leu-Cys (Disulfide bridge: Cys15-Cys21). Grade: ≥98%. Molecular formula: C87H155N23O24S2. Mole weight: 1971.45.
Nigrosin-RA1 peptide precursor
Nigrosin-RA1 peptide precursor is an antimicrobial peptide found in Odorrana andersonii (golden crossband frog), and has antimicrobial activity. Synonyms: Thr-Met-Lys-Lys-Ser-Leu-Leu-Leu-Leu-Phe-Phe-Phe-Gly-Thr-Ile-Asn-Leu-Ser-Phe-Cys-Gln. Grade: ≥96%. Molecular formula: C117H183N25O28S2. Mole weight: 2452.02.
Nigrosin, Saturated Aqueous, Laboratory Grade, 100 mL
Notes: Water-soluble stain. Health Risk: 2. Flammability: 1. Reactivity: 1. Group: chem-category biological stains. Grades: chem-grade laboratory. CAS No. 8005-03-6. Product ID: 877383. -- SOLD FOR EDUCATIONAL USE ONLY --
Nigrosin, Saturated Aqueous, Laboratory Grade, 500 mL
Notes: Water-soluble stain. Storage Code: Green; general chemical storage. Group: chem-category biological stains. Grades: chem-grade laboratory. CAS No. 8005-03-6. Product ID: 877385. -- SOLD FOR EDUCATIONAL USE ONLY --
NIH-12848
NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ with an IC50 of approximately 1 μM but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 is a potentially powerful tool for exploring the cell physiology of PI5P4Ks. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NIH-12848; NIH 12848; NIH12848, NCGC00012848-02. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 959551-10-1. Molecular formula: C20H14F3N3S. Mole weight: 385.41. Purity: >98%. IUPACName: N-(thiophen-2-ylmethyl)-2-(2-(trifluoromethyl)phenyl)quinazolin-4-amine. Canonical SMILES: FC(F)(F)C(C=CC=C1)=C1C2=NC3=CC=CC=C3C(NCC4=CC=CS4)=N2. Product ID: ACM959551101. Alfa Chemistry ISO 9001:2015 Certified.
NIH3T3 Transfection Reagent
Transfection Reagent for NIH3T3 Swiss Mouse Fibroblast Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 3212.
Nikethamide (N,N-Diethylnicotinamide), one of the respiratory central stimulants, has the potential for respiratory failure research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N,N-Diethylnicotinamide. CAS No. 59-26-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1280.
Nikkol GO
Nikkol GO. Group: Solubilizer. Alternative Names: Nikkol GO 4; Nikkol GO; Nikkol GO 440; Nikkol GO 460; Polyoxyethylene sorbitol tetraoleate; Ethoxylated sorbitol,tetraoleate; Nikkol GO 430; GO 430; Nikkol GO 430N. CAS No. 63089-86-1. Product ID: (Z)-octadec-9-enoic acid; 2-[2,3,4,5,6-pentakis(2-hydroxyethoxy)hexoxy]ethanol. Molecular formula:
Nikkomycin Lx is originally isolated from Streptomyces tendae TU901. Although it is a microcomponent, it is relatively stable and has stronger anti-candida albicans activity than other components. Molecular formula: C21H27N5O9. Mole weight: 493.47.
Nikkomycin Lz
Nikkomycin Lz is originally isolated from Streptomyces tendae TU901. Although it is a microcomponent, it is relatively stable and has stronger anti-candida albicans activity than other components. Molecular formula: C20H25N5O9. Mole weight: 479.44.
Nikkomycin Z is a nucleotide peptide from Streptomyces tendae with antifungal effects. Nikkomycin Z is a selective and competitive inhibitor of chitin synthesis and acts as a competitive analog of the chitin synthetase substrate UDP-N-acetylglucosamine. Synonyms: Nikkomycin; Neopolyoxin C; β-D-Allofuranuronic acid, 5-[[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-1,5-dideoxy-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-; (2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-β-D-allo-furanuronic acid. Grade: 95%. CAS No. 59456-70-1. Molecular formula: C20H25N5O10. Mole weight: 495.44.
Nikkomycin Z
Nikkomycin Z is a nucleoside peptide and an orally active antifungal agent. Nikkomycin Z inhibits chitin synthesis by acting as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine. Nikkomycin Z has antifungal activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59456-70-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-19593.
NIK SMI1
NIK SMI1 is a potent, selective NF-?B inducing kinase (NIK) inhibitor, which inhibits NIK-catalyzed hydrolysis of ATP to ADP with IC50 of 0.23±0.17 nM. NIK SMI1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1660114-31-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112433.
Nile Blue A certified
Nile Blue A certified. Group: Biochemicals. Alternative Names: Basic Blue; CI 5118. Grades: Highly Purified. CAS No. 3625-57-8. Pack Sizes: 50g, 100g, 250g. US Biological Life Sciences.
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Nile Blue A, Certified
Nile Blue A, Certified. Group: Biochemicals. Grades: Certified Dye. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences.
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Nile Blue Acrylamide
Nile Blue Acrylamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Benzo[a]phenoxazin-7-ium, 9-(diethylamino)-5-[(1-oxo-2-propen-1-yl)amino]-, chloride (1:1). Product Category: Acrylate Monomers. CAS No. 2089099-00-1. Molecular formula: C23H22N3O2CI. Mole weight: 408 g/mol. Product ID: ACM-MO-2089099001. Alfa Chemistry ISO 9001:2015 Certified.
Nile Blue A perchlorate
Nile Blue A perchlorate. Group: other materials. CAS No. 53340-16-2. Product ID: (5-aminobenzo[a]phenoxazin-9-ylidene)-diethylazanium; perchlorate. Molecular formula: 417.8g/mol. Mole weight: C20H20ClN3O5. CC[N+] (=C1C=CC2=NC3=C (C=C (C4=CC=CC=C43)N)OC2=C1)CC. [O-]Cl (=O) (=O)=O. InChI=1S/C20H19N3O. ClHO4/c1-3-23 (4-2)13-9-10-17-18 (11-13)24-19-12-16 (21)14-7-5-6-8-15 (14)20 (19)22-17; 2-1 (3, 4)5/h5-12, 21H, 3-4H2, 1-2H3; (H, 2, 3, 4, 5). OUAWJLNOTQAOHL-UHFFFAOYSA-N.
Nile blue chloride
Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2381-85-3. Pack Sizes: 1 g. Product ID: HY-W110898.
Nile Blue Chloride
Nile Blue Chloride. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g. US Biological Life Sciences.
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Nile Red
Alfa Chemistry offers Nile Red products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: Nile red has applications in cell biology, it can be used as a membrane dye, can be easily observed using epifluorescence microscopy, and its excitation and emission wavelengths are often shared with red fluorescent proteins. nile red has also been used as part of a sensitive detection process for microplastics in bottled water. furthermore, nile red is an excellent candidate for the fabrication of membranes for different sensors to detect environmental changes such as taste, gas, ph, etc. Group: Electroluminescence materials other materials. Alternative Names: 9-(Diethylamino)-5H-benzo[a]phenoxazin-5-one. CAS No. 7385-67-3. Product ID: 9-(diethylamino)benzo[a]phenoxazin-5-one. Molecular formula: 318.38. Mole weight: C20H18N2O2. CCN (CC)C1=CC2=C (C=C1)N=C3C4=CC=CC=C4C (=O)C=C3O2. InChI=1S/C20H18N2O2/c1-3-22 (4-2)13-9-10-16-18 (11-13)24-19-12-17 (23)14-7-5-6-8-15 (14)20 (19)21-16/h5-12H, 3-4H2, 1-2H3. VOFUROIFQGPCGE-UHFFFAOYSA-N. >98.0%(HPLC).
Nile Red
Nile red (Nile blue oxazone) is a lipophilic stain. Nile red has environment-sensitive fluorescence. Nile red is intensely fluorescent in a lipid-rich environment while it has minimal fluorescence in aqueous media. Nile red is an excellent vital stain for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytof uorometry. Nile red stains intracellular lipid droplets red. The fluorescence wavelength is 559/635 nm [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Nile Blue A oxazone; Phenoxazone 9. CAS No. 7385-67-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-D0718.
Nile Red
Nile Red. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
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Nilestriol
Nilestriol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NILESTRIOL;nylestriol;3-(cyclopentyloxy)-17alpha-ethinyl-1,3,5(10)-estratrien-16alpha,17beta-diol;17alpha-ethynylestra-1,3,5(10)-triene-3,16alpha,17beta-triol 3-cyclopentyl ether;17α-Ethynyl-3-cyclopentyloxyestra-1,3,5(10)-triene-16α,17β-diol;(8R,9S,13S. Product Category: Steroidal Compounds. CAS No. 39791-20-3. Molecular formula: C25H32O3. Mole weight: 380.52. Purity: 95%+. IUPACName: Nilestriol. Density: 1.21 g/cm³. Product ID: ACM39791203. Alfa Chemistry ISO 9001:2015 Certified.
Niloticin
Niloticin, isolated from the barks of Phellodendron chinense, presented 83.2% ovicidal activity at 2ppm concentration after 120h post treatment and Niloticin exhibited significant growth disruption and morphological deformities at sub lethal concentrations against Ae. Synonyms: (23R,24S)-24,25-Epoxy-23-hydroxy-5α-tirucall-7-en-3-one. Grade: >98%. CAS No. 115404-57-4. Molecular formula: C30H48O3. Mole weight: 456.7.
Nilotinib
Nilotinib is an orally available Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMN107. CAS No. 641571-10-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-10159.
Nilotinib 3-Imidazolyl N-Difluoroboryloxide
Nilotinib 3-Imidazolyl N-Difluoroboryloxide. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS002584. Format: Neat.
Nilotinib 3-Imidazolyl N-oxide
Nilotinib 3-Imidazolyl N-oxide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2139382-75-3. IUPAC Name: 4-methyl-N-[3-(4-methyl-3-oxo-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzamide. Molecular formula: C28H22F3N7O2. Mole weight: 545.52. Catalog: APS2139382753. SMILES: Cc1ccc(cc1Nc2nccc(n2)c3cccnc3)C(=O)Nc4cc(cc(c4)C(F)(F)F)n5cc(C)n(=O)c5. Format: Neat.
Nilotinib-d3
Labeled analog of Nilotinib (AMN1O7), which might be useful in treatment of chronic myelogenous leukemia. Group: Biochemicals. Alternative Names: 4-Methyl-N- [3- (4- (methyl-d3) -1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl] -3- [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] benzamide; AMN 107-d3; Tasigna-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Nilotinib-[d3]
Nilotinib-[d3] is the Labelled analog of Nilotinib, which may be used to treat chronic myelogenous leukemia. Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM. Synonyms: Nilotinib D3; 4-Methyl-N-{3-[4-(2H3)methyl-1H-imidazol-1-yl]-5-(trifluoromethyl)phenyl}-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide. Grade: 97%; 98% atom D. CAS No. 1215678-43-5. Molecular formula: C28H19D3F3N7O. Mole weight: 532.53.
Nilotinib-[d6]
Nilotinib-[d6] is the Labelled analog of Nilotinib, which may be used to treat chronic myelogenous leukemia. Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM. Synonyms: Nilotinib D6; 4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide-d6. Grade: 95% by HPLC; 95% atom D. CAS No. 1268356-17-7. Molecular formula: C28H16D6F3N7O. Mole weight: 535.55.
Nilotinib EP Impurity B
Nilotinib EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18595-18-1. Molecular formula: C9H11NO2. Mole weight: 165.19. Catalog: APB18595181.
Nilotinib, Free Base (AMN107)
Nilotinib, a novel, selective BCR-ABL inhibitor, fits into the ATP-binding site of the BCR-ABL protein with higher affinity than imatinib. Nilotinib is not only more potent than imatinib against wild-type BCR-ABL (IC50 < 30nM), but also significantly active against 32/33 imatinib-resistant BCR-ABL mutants. Group: Biochemicals. Alternative Names: 4-Methyl-N- [3- (4-methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl] -3- [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] benzamide; AMN107; Tasigna. Grades: Highly Purified. CAS No. 641571-10-0. Pack Sizes: 25mg. US Biological Life Sciences.
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Nilotinib monohydrochloride monohydrate
Nilotinib monohydrochloride monohydrate is a second generation tyrosine kinase inhibitor (TKI), is significantly potent against BCR-ABL, and is active against many BCR-ABL mutants. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMN107 monohydrochloride monohydrate. CAS No. 923288-90-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10159A.
Nilotinib N-Oxide
A metabolite of Nilotinib. Group: Biochemicals. Alternative Names: 4-Methyl-N- [3- (4-methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl] -3- [ [4- (3-pyridinyl-N-oxide) -2-pyrimidinyl] amino] benzamide. Grades: Highly Purified. CAS No. 1246817-85-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Nilutamide
Nilutamide (Nilandron) is an orally active nonsteroidal androgen receptor antagonist with affinity for androgen receptors but not for progestogen, estrogen or glucocorticoid receptors. Nilutamide can be used to research prostate cancer. Nilutamide also has antischistosomal properties [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nilandron; RU 23908. CAS No. 63612-50-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-13702.
Nilutamide
Nonsteroidal antiandrogen. Antineoplastic (hormonal). Group: Biochemicals. Alternative Names: 5, 5-Dimethyl-3-[4-nitro-3- (trifluoromethyl) phenyl]-2, 4-imidazolidinedion; 1-3-Trifluoromethyl-4-nitrophenyl)-4,4-dimethylimidazoline-2,5-dione; Anandron. Grades: Highly Purified. CAS No. 63612-50-0. Pack Sizes: 500mg, 1g, 5g. Molecular Formula: C??H??F?N?O?, Molecular Weight: 317.22. US Biological Life Sciences.
Nilutamide-[d6] is a labelled Nilutamide. Nilutamide is a nonsteroidal antiandrogen used for prostate cancer therapy. Synonyms: 5,5-(Dimethyl-d6)-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedion; 1-(3-Trifluoromethyl-4-nitrophenyl)-4,4-(dimethyl-d6)imidazoline-2,5-dione; Anandron-d6; Nilandron-d6; Nilandrone-d6; RU 23908-d6; RU 23908-10-d6. Grade: >95%. CAS No. 1189477-66-4. Molecular formula: C12H4D6F3N3O4. Mole weight: 323.26.
Nilvadipine
Nilvadipine is a potent calcium channel antagonist, and the IC 50 value is around 0.1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FK235; FR34235. CAS No. 75530-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-14284.
Used as an antihypertensive and antianginal. Nilvadipine is prescribed for patients with both hypertension and chronic major cerebral artery occlusion. In hypertensive patients with high risk of atherosclerosis, nilvadipine may protect LDL cholesterol from in vivo oxidation. Nilvadipine reduces infarction foci, improves cerebral microcirculation, but does not affect the systemic arterial blood pressure. Pathohistochemical studies have revealed that the volume of the infarction in the middle cerebral artery occlusion model could be decreased by nilvadipine. Although it is a dihydropyridine derivative, nilvadipine has several kinetic, dynamic, and therapeutic effects that are different from even those of the other voltage-dependent Ca2+ channel blockers belonging to the same class. Nilvadipine could easily be transmitted to the central nervous system. Moreover, vascular smooth muscles contracted by potassium were reported to be inhibited by nilvadipine. It antagonizes both L- and T-type Group: Biochemicals. Alternative Names: 2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl 5-(1-Methylethyl) Ester, FR-34235, SKF-102362, Escor. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
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Nilvadipine-[d3]
Nilvadipine-[d3] is the labelled analogue of Nilvadipine, which is a potent calcium channel blocker with an IC50 of 0. 03 nM. Synonyms: Nilvadipine D3; 2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-(Methyl-d3) 5-(1-methylethyl) Ester. Grade: 95% by HPLC; 95% atom D. CAS No. 95326-14-0. Molecular formula: C19H16D3N3O6. Mole weight: 388.39.