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Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica). Nimbolide induces apoptosis through inactivation of NF-κB. Nimbolide inhibits CDK4/CDK6 kinase activity. Nimbolide suppresses the NF-κB, Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways. Group: Inhibitors. CAS No. 25990-37-8. Molecular formula: C27H30O7. Mole weight: 466.52. Appearance: Powder. Purity: 0.98. IUPACName: methyl 2-[6-(furan-3-yl)-7, 9, 11, 15-tetramethyl-12, 16-dioxo-3, 17-dioxapentacyclo[9.6.1.02, 9.04, 8.015, 18]octadeca-7, 13-dien-10-yl]acetate. Canonical SMILES: CC1=C2C (CC1C3=COC=C3)OC4C2 (C (C5 (C6C4OC (=O)C6 (C=CC5=O)C)C)CC (=O)OC)C. Catalog: ACM25990378.
Nimbolide
Nimbolide, a natural triterpenoid present in the edible parts of the neem tree (Azadirachta indica), was found to be growth-inhibitory in human colon carcinoma HT-29 cells. Nimbolide treatment of cells at 2.5-0uM resulted in moderate to very strong growth inhibition. Group: Biochemicals. Alternative Names: (4α, 5α, 6α, 7α, 15 β,17α)-. Grades: Highly Purified. CAS No. 25990-37-8. Pack Sizes: 1mg. US Biological Life Sciences.
A terpenoid lactone derived from Azadirachta indica (Neem tree) that displays a variety of biological activities including anti-malarial and anticancer activity. Recently it has also been shown that nimbolide sensitizes colon cancer cells to TRAIL-induced apoptosis through three distinct mechanisms: reactive oxygen species and ERK-mediated up-regulation of DR5 and DR4, downregulation of cell survival proteins, and up-regulation of pro-apoptotic proteins p53 and Bax. Group: Biochemicals. Grades: Highly Purified. CAS No. 25990-37-8. Pack Sizes: 5mg. US Biological Life Sciences.
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Nimesulide
Nimesulide. Group: Biochemicals. Grades: Purified. CAS No. 51803-78-2. Pack Sizes: 100mg. US Biological Life Sciences.
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Nimesulide
Nimesulide is a selective COX-2 inhibitor, with IC 50 s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC 50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R805. CAS No. 51803-78-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0363.
Nimesulide
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C13H12N2O5S. CAS No. 51803-78-2. Prepack ID 39056848-5g. Molecular Weight 308.31. See USA prepack pricing.
Nimesulide
Nimesulide is a selective COX-2 inhibitor. Synonyms: N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide. Grades: > 95%. CAS No. 51803-78-2. Molecular formula: C13H12N2O5S. Mole weight: 308.3.
Nimesulide-D5
Nimesulide-D5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1330180-22-7. Molecular Formula: C13H7D5N2O5S. Mole Weight: 313.34. Catalog: APB1330180227.
Nimesulide EP impurity A
Nimesulide EP impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 51765-56-1. Molecular Formula: C13H11N3O7S. Mole Weight: 353.31. Catalog: APB51765561.
Nimesulide EP impurity B
Nimesulide EP impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 51765-51-6. Molecular Formula: C13H13NO3S. Mole Weight: 263.31. Catalog: APB51765516.
Nimesulide EP impurity C
Nimesulide EP impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2688-84-8. Molecular Formula: C12H11NO. Mole Weight: 185.23. Catalog: APB2688848.
Nimesulide EP impurity D
Nimesulide EP impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 5422-92-4. Molecular Formula: C12H10N2O3. Mole Weight: 230.22. Catalog: APB5422924.
Nimesulide EP impurity E
Nimesulide EP impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 905858-63-1. Molecular Formula: C14H15NO5S2. Mole Weight: 341.4. Catalog: APB905858631.
Nimesulide EP impurity F
Nimesulide EP impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 51765-72-1. Molecular Formula: C14H14N2O7S2. Mole Weight: 386.39. Catalog: APB51765721.
Nimesulide EP impurity G
Nimesulide EP impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 70995-08-3. Molecular Formula: C12H9NO4. Mole Weight: 231.21. Catalog: APB70995083.
Nimesulide Impurity A
An impurity of Nimesulide, which is a selective COX-8 inhibitor. Synonyms: N-(2,4-Dinitro-6-phenoxyphenyl)methanesulfonamide; N-(2,4-Dinitro-6-phenoxyphenyl)methanesulphonamide. Grades: > 95%. CAS No. 51765-56-1. Molecular formula: C13H11N3O7S. Mole weight: 353.31.
Nimesulide Impurity B
An impurity of Nimesulide, which is a selective COX-6 inhibitor. Synonyms: N-(2-Phenoxyphenyl)methanesulphonamide;N-(2-Phenoxyphenyl)methanesulphonamide; N-(2-phenoxyphenyl)methanesulfonamide; (2-Phenoxy)Methylsulfonylaniline. Grades: > 95%. CAS No. 51765-51-6. Molecular formula: C13H13NO3S. Mole weight: 263.32.
Nimesulide Impurity D
An impurity of Nimesulide, which is a selective COX-3 inhibitor. Synonyms: 4-Nitro-2-phenoxyaniline; 4-Nitro-2-phenoxybenzenamine; 2-Amino-5-nitrodiphenyl Ether; 2-Phenoxy-4-nitroaniline. Grades: > 95%. CAS No. 5422-92-4. Molecular formula: C12H10N2O3. Mole weight: 230.23.
Nimesulide Impurity E
An impurity of Nimesulide, which is a selective COX-7 inhibitor. Synonyms: N-(Methylsulfonyl)-4-(desnitro) Nimesulide; N-(Methylsulfonyl)-N-(2-phenoxyphenyl)methanesulfonamide. Grades: > 95%. CAS No. 905858-63-1. Molecular formula: C14H15NO5S2. Mole weight: 341.41.
Nimesulide Impurity F
An impurity of Nimesulide, which is a selective COX-5 inhibitor. Synonyms: N-Methylsulfonyl Nimesulide; N-(Methylsulfonyl)-N-(4-nitro-2-phenoxyphenyl)methanesulfonamide; N-(Methylsulfonyl)-4'-nitro-2'-phenoxymethanesulfonanilide. Grades: > 95%. CAS No. 51765-72-1. Molecular formula: C14H14N2O7S2. Mole weight: 386.4.
Nimesulide Impurity G
An impurity of Nimesulide, which is a selective COX-9 inhibitor. Synonyms: 4-Nitro-2-phenoxyphenol; Phenyl-(5-nitro-2-hydroxy-phenyl)-aether. Grades: > 95%. CAS No. 70995-08-3. Molecular formula: C12H9NO4. Mole weight: 231.21.
Intermediate in the production of labeled L-Ergothioneine. Group: Biochemicals. Alternative Names: 1-(Ethoxycarbonyl)-2-[(ethoxycarbonyl)thio]-N,N-dimethyl-L-histidine-d6 Methyl Ester. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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Nimodipine
Nimodipine (BAY-e 9736) is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist. Nimodipine can be used for the research of cerebrovascular disorders [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-e 9736. CAS No. 66085-59-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0265.
Nimodipine
Nimodipine. Group: Biochemicals. Grades: Purified. CAS No. 66085-59-4. Pack Sizes: 100mg. US Biological Life Sciences.
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Nimodipine
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C21H26N2O7. CAS No. 66085-59-4. Prepack ID 18892332-1g. Molecular Weight 418.44. See USA prepack pricing.
Nimodipine
Nimodipine is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy. Uses: Antihypertensive agents. Synonyms: LY127809; LY 127809; LY-127809; Nimodipine, Nimotop, Periplum, BAY E 9736, BAY-E-9736, BAYE9736. Grades: >98%. CAS No. 66085-59-4. Molecular formula: C21H26N2O7. Mole weight: 418.44.
Nimodipine (Bay e 9736, Admon, Nimotop, periplum)
Used as a cerebral vasodilator. A dihydropyridine calcium channel blocker. Group: Biochemicals. Alternative Names: Bay e 9736, Admon, Nimotop, periplum. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences.
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Nimodipine-d7
A labeled dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral). Group: Biochemicals. Alternative Names: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-. Grades: Highly Purified. CAS No. 1246815-36-0. Pack Sizes: 10mg. US Biological Life Sciences.
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Nimodipine-d7
Heterocyclic Organic Compound. Alternative Names: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-. CAS No. 1246815-36-0. Molecular formula: C21H19D7N2O7. Mole weight: 425.48. Appearance: Pale Yellow Solid. Purity: 0.96. IUPACName: 2-Methoxyethyl (2H7)-2-propanyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dih. Catalog: ACM1246815360.
Nimodipine EP Impurity B
Nimodipine EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. CAS No. 21881-78-7. Molecular Formula: C21H26N2O6. Mole Weight: 402.44. Catalog: APB21881787.
Nimodipine Impurity 10
Nimodipine Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 64163-94-6. Molecular Formula: C4H8N2O. Mole Weight: 100.12. Catalog: APB64163946.
Nimodipine Impurity 11
Nimodipine Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 85677-95-8. Molecular Formula: C18H20N2O7. Mole Weight: 376.36. Catalog: APB85677958.
Nimodipine Impurity 12
Nimodipine Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 39562-18-0. Molecular Formula: C19H22N2O6. Mole Weight: 374.39. Catalog: APB39562180.
Nimodipine Impurity 14
Nimodipine Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 155861-24-8. Molecular Formula: C21H28N2O5. Mole Weight: 388.46. Catalog: APB155861248.
Nimodipine Impurity 16
Nimodipine Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 58368-87-9. Molecular Formula: C19H23N3O6. Mole Weight: 389.4. Catalog: APB58368879.
Nimodipine Impurity 17 (Nicardipine Impurity 12)
Nimodipine Impurity 17 (Nicardipine Impurity 12). Uses: For analytical and research use. Group: Impurity standards. CAS No. 123973-71-7. Molecular Formula: C25H27N3O6. Mole Weight: 465.51. Catalog: APB123973717.
Nimodipine Impurity 18
Nimodipine Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 87966-40-3. Molecular Formula: C18H17ClN2O6. Mole Weight: 392.79. Catalog: APB87966403.
Nimodipine Impurity 19
Nimodipine Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 21112-45-8. Molecular Formula: C4H7NO2. Mole Weight: 101.11. Catalog: APB21112458.
Nimodipine Impurity 20
Nimodipine Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H26N2O6. Mole Weight: 402.45. Catalog: APB08746.
Nimodipine Impurity 21
Nimodipine Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 144757-56-2. Molecular Formula: C19H22N2O6. Mole Weight: 374.39. Catalog: APB144757562.
Nimodipine Impurity 22
Nimodipine Impurity 22. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H26N2O6. Mole Weight: 402.45. Catalog: APB08747.
Nimodipine Impurity 4
Nimodipine Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-((2-methoxyethoxy)carbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid. Molecular Formula: C18H20N2O7. Mole Weight: 376.36. Catalog: APB01437.
Nimodipine Impurity 4 (Nitrendipine Impurity H)
Nimodipine Impurity 4 (Nitrendipine Impurity H). Uses: For analytical and research use. Group: Impurity standards. CAS No. 74936-69-9. Molecular Formula: C18H20N2O6. Mole Weight: 360.36. Catalog: APB74936699.
Nimodipine Impurity 6
Nimodipine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 39562-21-5. Molecular Formula: C20H24N2O6. Mole Weight: 388.42. Catalog: APB39562215.
Nimodipine Impurity 8
Nimodipine Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 24871-74-7. Molecular Formula: C12H18O7. Mole Weight: 274.27. Catalog: APB24871747.
Nimodipine Impurity 9
Nimodipine Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 203740-59-4. Molecular Formula: C14H24N2O5. Mole Weight: 300.36. Catalog: APB203740594.
Nimodipine Impurity A
An impurity of Nimodipine, which is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity. Synonyms: Dehydro Nimodipine; 2,6-Dimethyl-4-(3-nitrophenyl)-,3,5-pyridinedicarboxylic Acid 3-(2-Methoxyethyl) 5-(1-Methylethyl) Ester; 2,6-Dimethyl-4-(3-nitrophenyl)- 3,5-pyridinedicarboxylic Acid 2-Methoxyethyl 1-Methylethyl Ester; USP Nimodipine Related Compound A; Nimodipine EP Impurity A. Grades: > 95%. CAS No. 85677-93-6. Molecular formula: C21H24N2O7. Mole weight: 416.43.
Nimodipine Metabolite 1
Nimodipine Metabolite 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 85677-99-2. Molecular Formula: C17H14N2O7. Mole Weight: 358.31. Catalog: APB85677992.
Nimodipine Metabolite 2
Nimodipine Metabolite 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 663163-06-2. Molecular Formula: C21H26N2O8. Mole Weight: 434.44. Catalog: APB663163062.
Nimodipine Metabolite 3
Nimodipine Metabolite 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 82219-48-5. Molecular Formula: C20H22N2O7. Mole Weight: 402.4. Catalog: APB82219485.
Nimodipine Metabolite 4
Nimodipine Metabolite 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 82219-47-4. Molecular Formula: C20H24N2O7. Mole Weight: 404.42. Catalog: APB82219474.
Nimorazole
Nimorazole is a nitroimidazole anti-infective. It significantly improves the effect of radiotherapeutic management of supraglottic and pharynx tumors and can be given without major side-effects. It is also the only such agent to have shown a significant effect in a randomized controlled trial in head and neck cancer. Uses: Antitrichomonal agents. Synonyms: Nitrimidazine; Naxogin. Grades: >98%. CAS No. 6506-37-2. Molecular formula: C9H14N4O3. Mole weight: 226.23.
Nimorazole
Nimorazole. Group: Biochemicals. Alternative Names: 4-[2-(5-Nitro-1H-imidazol-1-yl)ethyl]morpholine; 1-( β-Morpholinoethyl)-5-nitroimidazole; 4-[2-(5-Nitroimidazol-1-yl)ethyl]morpholine; Acterol; Esclama; K-1900; NSC 107524; Naxofem; Naxogin; Nimorazol; Nimorazole; Nitrimidazine; Nulogyl. Grades: Highly Purified. CAS No. 6506-37-2. Pack Sizes: 1g. Molecular Formula: C9H14N4O3, Molecular Weight: 226.23. US Biological Life Sciences.
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Nimorazole
Nimorazole (K-1900), a 2-nitroimidazole, is a hypoxic cell-radiation sensitizer. Nimorazole has anti-infective and anti-protozoal against trichomoniasis. Nimorazole has the potential for head and neck cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: K-1900. CAS No. 6506-37-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-16349.
Nimotuzumab is a humanized IgG1 monoclonal antibody targeting EGFR with a K D of 0.21 nM. Nimotuzumab is directed against the extracellular domain of the EGFR blocking the binding to its ligands. Nimotuzumab, a strong antitumor agent, is cytolytic on target tumors by its capacity to cause antibody dependent cell mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 780758-10-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9968.
Nim-Trityl-D-histidine
Nim-Trityl-D-histidine. Group: Biochemicals. Alternative Names: D-His(Trt)-OH. Grades: Highly Purified. CAS No. 199119-46-5. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
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Nim-Trityl-D-histidine
Nim-Trityl-D-histidine is used as a reagent in solid-phase synthesis and screening of peptides as catalysts for asymmetric induction of desymmetrization of bis(phenol)s. Synonyms: D-His(Trt)-OH; (2R)-2-amino-3-(1-tritylimidazol-4-yl)propanoic acid; Nim-Trityl-D-histidine; D-Histidine,1-(triphenylmethyl); H-D-His(Trt)-OH. Grades: ≥ 99% (HPLC). CAS No. 199119-46-5. Molecular formula: C25H23N3O2. Mole weight: 397.48.
Nim-Trityl-D-histidine 99+% (HPLC)
Nim-Trityl-D-histidine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Nim-Trityl-D-histidine methyl ester hydrochloride 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 2.5g. US Biological Life Sciences.
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Nim-Trityl-histidine
Nim-Trityl-histidine. Group: Biochemicals. Alternative Names: L-His(Trt)-OH. Grades: Highly Purified. CAS No. 35146-32-8. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Nim-Trityl-histidine 98+% (HPLC)
Nim-Trityl-histidine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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Nim-Trityl-L-histidine-2-chlorotrityl resin
Nim-Trityl-L-histidine-2-chlorotrityl resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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Nim-Trityl-L-histidine methyl ester hydrochloride
H-His(Trt)-OMe Hydrochloride is used to prepare Nα-methyl-Nα-(nitrobenzenesulfonyl)amino acids and their incorporation into dipeptides. It is also used to synthesize azaproline-based peptide analogs of TRH. Synonyms: L-His(Trt)-OMe HCl; methyl(2S)-2-amino-3-(1-tritylimidazol-4-yl)propanoate hydrochloride; H-His(Trt)-OMe. Grades: ≥ 99.5% (HPLC). CAS No. 32946-56-8. Molecular formula: C26H25N3O2·HCl. Mole weight: 448.00.