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NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ with an IC50 of approximately 1 μM but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 is a potentially powerful tool for exploring the cell physiology of PI5P4Ks. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NIH-12848; NIH 12848; NIH12848, NCGC00012848-02. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 959551-10-1. Molecular formula: C20H14F3N3S. Mole weight: 385.41. Purity: >98%. IUPACName: N-(thiophen-2-ylmethyl)-2-(2-(trifluoromethyl)phenyl)quinazolin-4-amine. Canonical SMILES: FC(F)(F)C(C=CC=C1)=C1C2=NC3=CC=CC=C3C(NCC4=CC=CS4)=N2. Product ID: ACM959551101. Alfa Chemistry ISO 9001:2015 Certified.
NIH-12848
NIH-12848 is putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor (IC50 = 1 μM) but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. Synonyms: N-(thiophen-2-ylmethyl)-2-[2-(trifluoromethyl)phenyl]quinazolin-4-amine; NCGC00012848-02; NIH-12848; NIH 12848; NIH12848, NCGC00012848-02. CAS No. 959551-10-1. Molecular formula: C20H14F3N3S. Mole weight: 385.41.
NIH3T3 Transfection Reagent
Transfection Reagent for NIH3T3 Swiss Mouse Fibroblast Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 3212.
Nikethamide (N,N-Diethylnicotinamide), one of the respiratory central stimulants, has the potential for respiratory failure research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N,N-Diethylnicotinamide. CAS No. 59-26-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1280.
Nikethamide Impurity 6
Nikethamide Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-isopropylnicotinamide. Molecular Formula: C9H12N2O. Mole Weight: 164.20. Catalog: APB01436.
Nikethamide Impurity 7
Nikethamide Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-ethyl-N-methylnicotinamide. Molecular Formula: C9H12N2O. Mole Weight: 164.20. Catalog: APB01378.
Nikethamide N-Oxide
Nikethamide N-Oxide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(diethylcarbamoyl)pyridine 1-oxide. CAS No. 20165-96-2. Molecular Formula: C10H14N2O2. Mole Weight: 194.23. Catalog: APB20165962.
Nikkol GO
Nikkol GO. Group: Solubilizer. Alternative Names: Nikkol GO 4; Nikkol GO; Nikkol GO 440; Nikkol GO 460; Polyoxyethylene sorbitol tetraoleate; Ethoxylated sorbitol,tetraoleate; Nikkol GO 430; GO 430; Nikkol GO 430N. CAS No. 63089-86-1. Product ID: (Z)-octadec-9-enoic acid; 2-[2,3,4,5,6-pentakis(2-hydroxyethoxy)hexoxy]ethanol. Molecular formula:
Nikkomycin Lx is originally isolated from Streptomyces tendae TU901. Although it is a microcomponent, it is relatively stable and has stronger anti-candida albicans activity than other components. Molecular formula: C21H27N5O9. Mole weight: 493.47.
Nikkomycin Lz
Nikkomycin Lz is originally isolated from Streptomyces tendae TU901. Although it is a microcomponent, it is relatively stable and has stronger anti-candida albicans activity than other components. Molecular formula: C20H25N5O9. Mole weight: 479.44.
Nikkomycin Z
Nikkomycin Z is a nucleoside peptide and an orally active antifungal agent. Nikkomycin Z inhibits chitin synthesis by acting as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine. Nikkomycin Z has antifungal activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59456-70-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-19593.
Nikkomycin Z
Nikkomycin Z. CAS No. 59456-70-1. Product ID: 1-00916. Molecular formula: C20H25N5O10. Mole weight: 495.45. Purity: Source : ex Streptomyces fendae.
Nikkomycin Z from Streptomyces tendae
Nikkomycin Z is a nucleotide peptide from Streptomyces tendae with antifungal effects. Nikkomycin Z is a selective and competitive inhibitor of chitin synthesis and acts as a competitive analog of the chitin synthetase substrate UDP-N-acetylglucosamine. Synonyms: Nikkomycin; Neopolyoxin C; β-D-Allofuranuronic acid, 5-[[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-1,5-dideoxy-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-; (2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-β-D-allo-furanuronic acid. Grades: ≥90% by HPLC. CAS No. 59456-70-1. Molecular formula: C20H25N5O10. Mole weight: 495.44.
NIK SMI1
NIK SMI1 is a potent and selective NF-κB inducing kinase (NIK) inhibitor. Synonyms: (R)-6-(3-((3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl)ethynyl)phenyl)-4-methoxypicolinamide. CAS No. 1660114-31-7. Molecular formula: C20H19N3O4. Mole weight: 365.4.
Nile Blue A certified
Nile Blue A certified. Group: Biochemicals. Alternative Names: Basic Blue; CI 5118. Grades: Highly Purified. CAS No. 3625-57-8. Pack Sizes: 50g, 100g, 250g. US Biological Life Sciences.
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Nile Blue A, Certified
Nile Blue A, Certified. Group: Biochemicals. Grades: Certified Dye. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences.
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Nile Blue Acrylamide
Nile Blue Acrylamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Benzo[a]phenoxazin-7-ium, 9-(diethylamino)-5-[(1-oxo-2-propen-1-yl)amino]-, chloride (1:1). Product Category: Acrylate Monomers. CAS No. 2089099-00-1. Molecular formula: C23H22N3O2CI. Mole weight: 408 g/mol. Product ID: ACM-MO-2089099001. Alfa Chemistry ISO 9001:2015 Certified.
Nile Blue A perchlorate
Nile Blue A perchlorate. Group: other materials. CAS No. 53340-16-2. Product ID: (5-aminobenzo[a]phenoxazin-9-ylidene)-diethylazanium; perchlorate. Molecular formula: 417.8g/mol. Mole weight: C20H20ClN3O5. CC[N+] (=C1C=CC2=NC3=C (C=C (C4=CC=CC=C43)N)OC2=C1)CC. [O-]Cl (=O) (=O)=O. InChI=1S/C20H19N3O. ClHO4/c1-3-23 (4-2)13-9-10-17-18 (11-13)24-19-12-16 (21)14-7-5-6-8-15 (14)20 (19)22-17; 2-1 (3, 4)5/h5-12, 21H, 3-4H2, 1-2H3; (H, 2, 3, 4, 5). OUAWJLNOTQAOHL-UHFFFAOYSA-N.
Nile blue chloride
Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2381-85-3. Pack Sizes: 1 g. Product ID: HY-W110898.
Nile Blue Chloride
Nile Blue Chloride. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g. US Biological Life Sciences.
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Nile Red
Nile Red. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
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Nile Red
Alfa Chemistry offers Nile Red products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: Nile red has applications in cell biology, it can be used as a membrane dye, can be easily observed using epifluorescence microscopy, and its excitation and emission wavelengths are often shared with red fluorescent proteins. nile red has also been used as part of a sensitive detection process for microplastics in bottled water. furthermore, nile red is an excellent candidate for the fabrication of membranes for different sensors to detect environmental changes such as taste, gas, ph, etc. Group: Electroluminescence materials other materials. Alternative Names: 9-(Diethylamino)-5H-benzo[a]phenoxazin-5-one. CAS No. 7385-67-3. Product ID: 9-(diethylamino)benzo[a]phenoxazin-5-one. Molecular formula: 318.38. Mole weight: C20H18N2O2. CCN (CC)C1=CC2=C (C=C1)N=C3C4=CC=CC=C4C (=O)C=C3O2. InChI=1S/C20H18N2O2/c1-3-22 (4-2)13-9-10-16-18 (11-13)24-19-12-17 (23)14-7-5-6-8-15 (14)20 (19)21-16/h5-12H, 3-4H2, 1-2H3. VOFUROIFQGPCGE-UHFFFAOYSA-N. >98.0%(HPLC).
Nile Red
Nile red (Nile blue oxazone) is a lipophilic stain. Nile red has environment-sensitive fluorescence. Nile red is intensely fluorescent in a lipid-rich environment while it has minimal fluorescence in aqueous media. Nile red is an excellent vital stain for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytof uorometry. Nile red stains intracellular lipid droplets red. The fluorescence wavelength is 559/635 nm [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Nile Blue A oxazone; Phenoxazone 9. CAS No. 7385-67-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-D0718.
Nilestriol
Nilestriol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NILESTRIOL;nylestriol;3-(cyclopentyloxy)-17alpha-ethinyl-1,3,5(10)-estratrien-16alpha,17beta-diol;17alpha-ethynylestra-1,3,5(10)-triene-3,16alpha,17beta-triol 3-cyclopentyl ether;17α-Ethynyl-3-cyclopentyloxyestra-1,3,5(10)-triene-16α,17β-diol;(8R,9S,13S. Product Category: Steroidal Compounds. CAS No. 39791-20-3. Molecular formula: C25H32O3. Mole weight: 380.52. Purity: 95%+. IUPACName: Nilestriol. Density: 1.21 g/cm³. Product ID: ACM39791203. Alfa Chemistry ISO 9001:2015 Certified.
Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM. It is under investigation as a possible treatment for chronic myelogenous leukemia (CML). Synonyms: Tasigna; AMN107; AMN 107; AMN-107; BW 33A, 51W89. Grades: ≥98%. CAS No. 641571-10-0. Molecular formula: C28H22F3N7O. Mole weight: 529.52.
Nilotinib 3-Imidazolyl N-Difluoroboryloxide
Nilotinib 3-Imidazolyl N-Difluoroboryloxide. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS002584. Format: Neat.
Nilotinib 3-Imidazolyl N-oxide
Nilotinib 3-Imidazolyl N-oxide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2139382-75-3. IUPAC Name: 4-methyl-N-[3-(4-methyl-3-oxo-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzamide. Molecular Formula: C28H22F3N7O2. Mole Weight: 545.52. Catalog: APS2139382753. SMILES: Cc1ccc (cc1Nc2nccc (n2)c3cccnc3)C (=O)Nc4cc (cc (c4)C (F) (F)F)n5cc (C)n (=O)c5. Format: Neat.
Nilotinib-d3
Labeled analog of Nilotinib (AMN1O7), which might be useful in treatment of chronic myelogenous leukemia. Group: Biochemicals. Alternative Names: 4-Methyl-N- [3- (4- (methyl-d3) -1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl] -3- [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] benzamide; AMN 107-d3; Tasigna-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Nilotinib EP Impurity A
Nilotinib EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 641571-11-1. Molecular Formula: C11H10F3N3. Mole Weight: 241.22. Catalog: APB641571111.
Nilotinib EP Impurity B
Nilotinib EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18595-18-1. Molecular Formula: C9H11NO2. Mole Weight: 165.19. Catalog: APB18595181.
Nilotinib EP Impurity C
Nilotinib EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2458-12-0. Molecular Formula: C8H9NO2. Mole Weight: 151.17. Catalog: APB2458120.
Nilotinib EP Impurity D
Nilotinib EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 641569-94-0. Molecular Formula: C17H14N4O2. Mole Weight: 306.33. Catalog: APB641569940.
Nilotinib EP Impurity E
Nilotinib EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2119583-26-3. Molecular Formula: C27H20F3N7O. Mole Weight: 515.5. Catalog: APB2119583263.
Nilotinib EP Impurity F
Nilotinib EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2119583-24-1. Molecular Formula: C29H24F3N7O. Mole Weight: 543.55. Catalog: APB2119583241.
Nilotinib EP Impurity G
Nilotinib EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 917392-54-2. Molecular Formula: C18H16N4O2. Mole Weight: 320.35. Catalog: APB917392542.
Nilotinib EP Impurity H
Nilotinib EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 641571-15-5. Molecular Formula: C28H22F3N7O. Mole Weight: 529.53. Catalog: APB641571155.
Nilotinib, Free Base (AMN107)
Nilotinib, a novel, selective BCR-ABL inhibitor, fits into the ATP-binding site of the BCR-ABL protein with higher affinity than imatinib. Nilotinib is not only more potent than imatinib against wild-type BCR-ABL (IC50 < 30nM), but also significantly active against 32/33 imatinib-resistant BCR-ABL mutants. Group: Biochemicals. Alternative Names: 4-Methyl-N- [3- (4-methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl] -3- [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] benzamide; AMN107; Tasigna. Grades: Highly Purified. CAS No. 641571-10-0. Pack Sizes: 25mg. US Biological Life Sciences.
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Nilotinib hydrochloride
Nilotinib is an orally bioavailable Bcr-Abl tyrosine kinase inhibitor displaying antineoplastic activity. It is promisingly used for the treatment of chronic myelogenous leukemia (CML). Uses: Tyrosine kinase inhibitors. Synonyms: AMN-107 HCl; 4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide hydrochloride. CAS No. 923288-95-3. Molecular formula: C28H22F3N7O·HCl. Mole weight: 565.98.
Nilotinib Hydrochloride
Nilotinib Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 923288-95-3. Molecular Formula: C28H23ClF3N7O. Mole Weight: 565.99. Catalog: APB923288953.
Nilotinib Hydrochloride Hydrate
Nilotinib Hydrochloride Hydrate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 923288-90-8. Molecular Formula: C28H25ClF3N7O2. Mole Weight: 584. Catalog: APB923288908.
Nilotinib Impurity 10
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 41 nM. Synonyms: tert-butyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate. Grades: > 95%. Molecular formula: C21H22N4O2. Mole weight: 362.44.
Nilotinib Impurity 11
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 42 nM. Synonyms: 4-Desmethyl-4-ethylimidazolyl Nilotinib; N-(3-(4-ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide. Grades: > 95%. Molecular formula: C29H24F3N7O. Mole weight: 543.56.
Nilotinib Impurity 12
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 43 nM. Synonyms: 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile; 3-(4-Methyl-imidazol-1-yl)-5-trifluoromethyl-benzonitrile. Grades: > 95%. CAS No. 641571-12-2. Molecular formula: C12H8F3N3. Mole weight: 251.21.
Nilotinib Impurity 13
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 44 nM. Synonyms: 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamide. Grades: > 95%. CAS No. 917391-28-7. Molecular formula: C12H10F3N3O. Mole weight: 269.23.
Nilotinib Impurity 1 HCl
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 32 nM. Synonyms: 3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline HCl. Grades: > 95%. Molecular formula: C12H12F3N3. HCl. Mole weight: 255.24 36.46.
Nilotinib Impurity 2
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 33 nM. Synonyms: 3-(2-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline. Grades: > 95%. CAS No. 641571-06-4. Molecular formula: C11H10F3N3. Mole weight: 241.22.
an Intermediate of Imatinib. Synonyms: (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one. Grades: > 95%. CAS No. 123367-26-0. Molecular formula: C10H12N2O. Mole weight: 176.22.
Nilotinib Impurity 3
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 34 nM. Synonyms: 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)-aniline. Grades: > 95%. CAS No. 943320-48-7. Molecular formula: C10H8F3N3. Mole weight: 227.19.
Nilotinib Impurity 4
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 35 nM. Synonyms: 3-(2,4-Dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline. Grades: > 95%. Molecular formula: C12H12F3N3. Mole weight: 255.24.
Nilotinib Impurity 6
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 37 nM. Synonyms: 4-methyl-N-(3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide. Grades: > 95%. Molecular formula: C28H22F3N7O. Mole weight: 529.53.
Nilotinib Impurity 7
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 38 nM. Synonyms: N-(3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide. Grades: > 95%. Molecular formula: C27H20F3N7O. Mole weight: 515.5.
Nilotinib Impurity 8
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 39 nM. Synonyms: N-(3-(2,4-dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide. Grades: > 95%. Molecular formula: C29H24F3N7O. Mole weight: 543.56.
Nilotinib Impurity 8
Nilotinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2119583-27-4. Molecular Formula: C12H12F3N3. Mole Weight: 255.24. Catalog: APB2119583274.
Nilotinib Impurity 9
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 40 nM. Synonyms: 4-Methyl-N-(3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)phenyl)-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzaMide. Grades: > 95%. CAS No. 641571-15-5. Molecular formula: C28H22F3N7O. Mole weight: 529.53.
Nilotinib Impurity 9
Nilotinib Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C37H29ClF3N11O. Mole Weight: 736.16. Catalog: APB10655.
Nilotinib monohydrochloride monohydrate
Nilotinib monohydrochloride monohydrate is an orally bioavailable aminopyrimidine-derivative Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity. It binds to and stabilizes the inactive conformation of the kinase domain of the Abl protein of the Bcr-Abl fusion protein, resulting in the inhibition of the Bcr-Abl-mediated proliferation of Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) cells. It also inhibits the receptor tyrosine kinases platelet-derived growth factor receptor (PDGF-R) and c-kit, a receptor tyrosine kinase mutated and constitutively activated in most gastrointestinal stromal tumors (GISTs). Uses: Tyrosine kinase inhibitors. Synonyms: AMN-107; AMN 107; AMN107; Tasigna. Grades: >98%. CAS No. 923288-90-8. Molecular formula: C28H25ClF3N7O2. Mole weight: 583.99.
Nilotinib N-Oxide
A metabolite of Nilotinib. Group: Biochemicals. Alternative Names: 4-Methyl-N- [3- (4-methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl] -3- [ [4- (3-pyridinyl-N-oxide) -2-pyrimidinyl] amino] benzamide. Grades: Highly Purified. CAS No. 1246817-85-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Nilotinib N-Oxide
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 30 nM. Synonyms: 4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl-N-oxide)-2-pyrimidinyl]amino]benzamide. Grades: > 95%. CAS No. 1246817-85-5. Molecular formula: C28H22F3N7O2. Mole weight: 545.53.
Niludipine
Niludipine, a safe antianginal Ca2+-antagonist, is a drug with broad effectiveness for various types of angina pectoris. Uses: Calcium channel blockers. Synonyms: BAY-a 7168; Bay a 7168; NILUDIPINE;(2-propoxyethyl)ester; 5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-bis; bay-a7168; bis(2-propoxyethyl)1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedi;niludipin; Bis(2-propoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl). Grades: >98%. CAS No. 22609-73-0. Molecular formula: C25H34N2O8. Mole weight: 490.55.
Nilutamide
Nilutamide is a non-steroidal and silent antiandrogen that binds to androgen receptors and also inhibits androgen biosynthesis in vitro. In rats in vivo it inhibits androgen-induced prostate weight increase and inhibits negative androgen-dependent gonadotropin feedback leading to an increase in luteinising hormone and testosterone. Uses: Antineoplastic agents. Synonyms: Anandron; Nilandron; 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione. Grades: >98%. CAS No. 63612-50-0. Molecular formula: C12H10F3N3O4. Mole weight: 317.224.
Nilutamide
Nonsteroidal antiandrogen. Antineoplastic (hormonal). Group: Biochemicals. Alternative Names: 5, 5-Dimethyl-3-[4-nitro-3- (trifluoromethyl) phenyl]-2, 4-imidazolidinedion; 1-3-Trifluoromethyl-4-nitrophenyl)-4,4-dimethylimidazoline-2,5-dione; Anandron. Grades: Highly Purified. CAS No. 63612-50-0. Pack Sizes: 500mg, 1g, 5g. Molecular Formula: C??H??F?N?O?, Molecular Weight: 317.22. US Biological Life Sciences.
Worldwide
Nilutamide
Nilutamide (Nilandron) is an orally active nonsteroidal androgen receptor antagonist with affinity for androgen receptors but not for progestogen, estrogen or glucocorticoid receptors. Nilutamide can be used to research prostate cancer. Nilutamide also has antischistosomal properties [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nilandron; RU 23908. CAS No. 63612-50-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-13702.
Nilvadipine is a potent calcium channel antagonist, and the IC 50 value is around 0.1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FK235; FR34235. CAS No. 75530-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-14284.
Nilvadipine
Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM. Uses: Antihypertensive agents. Synonyms: F-ara-A (NSC 312887) Phosphate; FR-34235, FK 235; FR 34235, FK-235; FR34235, FK235. Grades: >98%. CAS No. 75530-68-6. Molecular formula: C19H19N3O6. Mole weight: 385.37.