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| Product | Description | |
|---|---|---|
| Nilotinib EP Impurity B | Nilotinib EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18595-18-1. Molecular formula: C9H11NO2. Mole weight: 165.19. Catalog: APB18595181. |  |
| Nilotinib, Free Base (AMN107) | Nilotinib, a novel, selective BCR-ABL inhibitor, fits into the ATP-binding site of the BCR-ABL protein with higher affinity than imatinib. Nilotinib is not only more potent than imatinib against wild-type BCR-ABL (IC50 < 30nM), but also significantly active against 32/33 imatinib-resistant BCR-ABL mutants. Group: Biochemicals. Alternative Names: 4-Methyl-N- [3- (4-methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl] -3- [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] benzamide; AMN107; Tasigna. Grades: Highly Purified. CAS No. 641571-10-0. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| Nilotinib hydrochloride | Nilotinib is an orally bioavailable Bcr-Abl tyrosine kinase inhibitor displaying antineoplastic activity. It is promisingly used for the treatment of chronic myelogenous leukemia (CML). Uses: Tyrosine kinase inhibitors. Synonyms: AMN-107 HCl; 4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide hydrochloride. CAS No. 923288-95-3. Molecular formula: C28H22F3N7O·HCl. Mole weight: 565.98. |  |
| Nilotinib Impurity 10 | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 41 nM. Synonyms: tert-butyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate. Grades: > 95%. Molecular formula: C21H22N4O2. Mole weight: 362.44. | |
| Nilotinib Impurity 11 | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 42 nM. Synonyms: 4-Desmethyl-4-ethylimidazolyl Nilotinib; N-(3-(4-ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide. Grades: > 95%. Molecular formula: C29H24F3N7O. Mole weight: 543.56. | |
| Nilotinib Impurity 12 | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 43 nM. Synonyms: 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile; 3-(4-Methyl-imidazol-1-yl)-5-trifluoromethyl-benzonitrile. Grades: > 95%. CAS No. 641571-12-2. Molecular formula: C12H8F3N3. Mole weight: 251.21. | |
| Nilotinib Impurity 13 | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 44 nM. Synonyms: 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamide. Grades: > 95%. CAS No. 917391-28-7. Molecular formula: C12H10F3N3O. Mole weight: 269.23. | |
| Nilotinib Impurity 1 HCl | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 32 nM. Synonyms: 3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline HCl. Grades: > 95%. Molecular formula: C12H12F3N3. HCl. Mole weight: 255.24 36.46. | |
| Nilotinib Impurity 2 | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 33 nM. Synonyms: 3-(2-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline. Grades: > 95%. CAS No. 641571-06-4. Molecular formula: C11H10F3N3. Mole weight: 241.22. | |
| Nilotinib Impurity ((2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one) | an Intermediate of Imatinib. Synonyms: (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one. Grades: > 95%. CAS No. 123367-26-0. Molecular formula: C10H12N2O. Mole weight: 176.22. | |
| Nilotinib Impurity 3 | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 34 nM. Synonyms: 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)-aniline. Grades: > 95%. CAS No. 943320-48-7. Molecular formula: C10H8F3N3. Mole weight: 227.19. | |
| Nilotinib Impurity 4 | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 35 nM. Synonyms: 3-(2,4-Dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline. Grades: > 95%. Molecular formula: C12H12F3N3. Mole weight: 255.24. | |
| Nilotinib Impurity 6 | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 37 nM. Synonyms: 4-methyl-N-(3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide. Grades: > 95%. Molecular formula: C28H22F3N7O. Mole weight: 529.53. | |
| Nilotinib Impurity 7 | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 38 nM. Synonyms: N-(3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide. Grades: > 95%. Molecular formula: C27H20F3N7O. Mole weight: 515.5. | |
| Nilotinib Impurity 8 | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 39 nM. Synonyms: N-(3-(2,4-dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide. Grades: > 95%. Molecular formula: C29H24F3N7O. Mole weight: 543.56. | |
| Nilotinib Impurity 9 | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 40 nM. Synonyms: 4-Methyl-N-(3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)phenyl)-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzaMide. Grades: > 95%. CAS No. 641571-15-5. Molecular formula: C28H22F3N7O. Mole weight: 529.53. | |
| Nilotinib monohydrochloride monohydrate | Nilotinib monohydrochloride monohydrate is an orally bioavailable aminopyrimidine-derivative Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity. It binds to and stabilizes the inactive conformation of the kinase domain of the Abl protein of the Bcr-Abl fusion protein, resulting in the inhibition of the Bcr-Abl-mediated proliferation of Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) cells. It also inhibits the receptor tyrosine kinases platelet-derived growth factor receptor (PDGF-R) and c-kit, a receptor tyrosine kinase mutated and constitutively activated in most gastrointestinal stromal tumors (GISTs). Uses: Tyrosine kinase inhibitors. Synonyms: AMN-107; AMN 107; AMN107; Tasigna. Grades: >98%. CAS No. 923288-90-8. Molecular formula: C28H25ClF3N7O2. Mole weight: 583.99. | |
| Nilotinib N-Oxide | A metabolite of Nilotinib. Group: Biochemicals. Alternative Names: 4-Methyl-N- [3- (4-methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl] -3- [ [4- (3-pyridinyl-N-oxide) -2-pyrimidinyl] amino] benzamide. Grades: Highly Purified. CAS No. 1246817-85-5. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Nilotinib N-Oxide | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 30 nM. Synonyms: 4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl-N-oxide)-2-pyrimidinyl]amino]benzamide. Grades: > 95%. CAS No. 1246817-85-5. Molecular formula: C28H22F3N7O2. Mole weight: 545.53. | |
| Niludipine | Niludipine, a safe antianginal Ca2+-antagonist, is a drug with broad effectiveness for various types of angina pectoris. Uses: Calcium channel blockers. Synonyms: BAY-a 7168; Bay a 7168; NILUDIPINE;(2-propoxyethyl)ester; 5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-bis; bay-a7168; bis(2-propoxyethyl)1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedi;niludipin; Bis(2-propoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl). Grades: >98%. CAS No. 22609-73-0. Molecular formula: C25H34N2O8. Mole weight: 490.55. | |
| Nilutamide | Nilutamide is a non-steroidal and silent antiandrogen that binds to androgen receptors and also inhibits androgen biosynthesis in vitro. In rats in vivo it inhibits androgen-induced prostate weight increase and inhibits negative androgen-dependent gonadotropin feedback leading to an increase in luteinising hormone and testosterone. Uses: Antineoplastic agents. Synonyms: Anandron; Nilandron; 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione. Grades: >98%. CAS No. 63612-50-0. Molecular formula: C12H10F3N3O4. Mole weight: 317.224. | |
| Nilutamide | Nonsteroidal antiandrogen. Antineoplastic (hormonal). Group: Biochemicals. Alternative Names: 5, 5-Dimethyl-3-[4-nitro-3- (trifluoromethyl) phenyl]-2, 4-imidazolidinedion; 1-3-Trifluoromethyl-4-nitrophenyl)-4,4-dimethylimidazoline-2,5-dione; Anandron. Grades: Highly Purified. CAS No. 63612-50-0. Pack Sizes: 500mg, 1g, 5g. Molecular Formula: C??H??F?N?O?, Molecular Weight: 317.22. US Biological Life Sciences. | Worldwide |
| Nilutamide | Nilutamide (Nilandron) is an orally active nonsteroidal androgen receptor antagonist with affinity for androgen receptors but not for progestogen, estrogen or glucocorticoid receptors. Nilutamide can be used to research prostate cancer. Nilutamide also has antischistosomal properties [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nilandron; RU 23908. CAS No. 63612-50-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-13702. |  |
| Nilutamide-d6 | Nonsteroidal antiandrogen. Antineoplastic (hormonal). Group: Biochemicals. Alternative Names: 5, 5- (Dimethyl-d6) -3-[4-nitro-3- (trifluoromethyl) phenyl]-2, 4-imidazolidinedion; 1- (3-Trifluoromethyl-4-nitrophenyl) -4, 4- (dimethyl-d6) imidazoline-2, 5-dione; Anandron-d6; Nilandron-d6; Nilandrone-d6; RU 23908-d6; RU 23908-10-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Nilvadipine | Nilvadipine. Group: Biochemicals. Alternative Names: 2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-(1-methylethyl) ester, FR-34235, SKF-102362, escor. Grades: Highly Purified. CAS No. 75530-68-6. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C19H19N3O6. US Biological Life Sciences. | Worldwide |
| Nilvadipine | Nilvadipine is a potent calcium channel antagonist, and the IC 50 value is around 0.1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FK235; FR34235. CAS No. 75530-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-14284. | |
| Nilvadipine | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. Alternative Names: 3,5-Pyridinedicarboxylic acid, 2-cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, 3-methyl 5-(1-methylethyl) ester, Escor, FK 235, Nilvadipine, Nivadil, SKF 102362, FR 34235, (±)-Nilvadipine, Nivadip, CL 287389, Nivaldipine, dl-Nilvadipine. | |
| Nilvadipine | Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM. Uses: Antihypertensive agents. Synonyms: F-ara-A (NSC 312887) Phosphate; FR-34235, FK 235; FR 34235, FK-235; FR34235, FK235. Grades: >98%. CAS No. 75530-68-6. Molecular formula: C19H19N3O6. Mole weight: 385.37. | |
| Nilvadipine (2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl 5-(1-Methylethyl) Ester, FR-34235, SKF-102362, Escor) | Used as an antihypertensive and antianginal. Nilvadipine is prescribed for patients with both hypertension and chronic major cerebral artery occlusion. In hypertensive patients with high risk of atherosclerosis, nilvadipine may protect LDL cholesterol from in vivo oxidation. Nilvadipine reduces infarction foci, improves cerebral microcirculation, but does not affect the systemic arterial blood pressure. Pathohistochemical studies have revealed that the volume of the infarction in the middle cerebral artery occlusion model could be decreased by nilvadipine. Although it is a dihydropyridine derivative, nilvadipine has several kinetic, dynamic, and therapeutic effects that are different from even those of the other voltage-dependent Ca2+ channel blockers belonging to the same class. Nilvadipine could easily be transmitted to the central nervous system. Moreover, vascular smooth muscles contracted by potassium were reported to be inhibited by nilvadipine. It antagonizes both L- and T-type Group: Biochemicals. Alternative Names: 2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl 5-(1-Methylethyl) Ester, FR-34235, SKF-102362, Escor. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Nim-4-Methyltrityl-L-histidine | Synonyms: L-His(Mtt)-OH; (S)-2-Amino-3-(1-(diphenyl(p-tolyl)methyl)-1H-imidazol-4-yl)propanoic acid. Grades: ≥ 99% (TLC). CAS No. 133367-32-5. Molecular formula: C26H25N3O2. Mole weight: 411.51. | |
| Nim-4-Methyltrityl-L-histidine | Nim-4-Methyltrityl-L-histidine. Group: Biochemicals. Alternative Names: L-His(Mtt)-OH. Grades: Highly Purified. CAS No. 133367-32-5. Pack Sizes: 1g, 2g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| Nim-4-Methyltrityl-L-histidine 99+% (TLC) | Nim-4-Methyltrityl-L-histidine 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| NIM811 | NIM811 is a dual inhibitor of mitochondrial permeability transition and cyclophilin. It exhibits potent in vitro inhibitory activity against hepatitis C virus (HCV). Synonyms: (Melle-4)cyclosporin; Sdz-nim-811; NIM-811; NIM 811. Grades: 98.82%. CAS No. 143205-42-9. Molecular formula: C62H111N11O12. Mole weight: 1202.61. | |
| Nimbanal | Nimbin derivative. Group: Biochemicals. Alternative Names: (2R, 3aR, 4aS, 5R, 5aS, 6R, 9aR, 10S, 10aR) -5- (Acetyloxy) -6-formyl-2- (3-furanyl) -3, 3a, 4a, 5, 5a, 6, 9, 9a, 10, 10a-decahydro-1, 6, 9a, 10a-tetramethyl-9-oxo-2H-cyclopenta [b]naphtho [2, 3-d]furan-10-acetic Acid Methyl Ester; (4α, 5α, 6α, 7α, 15 β,17α)-6-(Acetyloxy)-7,15:21,23-diepoxy-4-formyl-4,8-dimethyl-1-oxo-24-nor-12,13-secochola-2,13,20,22-tetraen-12-oic Acid Methyl Ester. Grades: Highly Purified. CAS No. 120462-51-3. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Nim-Benzyl-D-histidine | Nim-Benzyl-D-histidine. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g. US Biological Life Sciences. | Worldwide |
| Nim-Benzyl-L-histidine | Synonyms: L-His(Bzl)-OH; 2-amino-3-(1-benzylimidazol-4-yl)propanoic acid; Nim-benzyl-L-histidine; 1-benzyl-histidine; im-Benzyl-L-histidine; 1-benzyl-L-histidine; N-BENZYL-L-HISTIDINE. Grades: ≥ 98% (TLC). CAS No. 16832-24-9. Molecular formula: C13H15N3O2. Mole weight: 245.28. | |
| Nim-Benzyl-L-histidine | Nim-Benzyl-L-histidine. Group: Biochemicals. Alternative Names: L-His(Bzl)-OH. Grades: Highly Purified. CAS No. 16832-24-9. Pack Sizes: 1g, 2g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| Nim-Benzyl-L-histidine 99+% (TLC) | Nim-Benzyl-L-histidine 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 16832-24-9. Pack Sizes: 1g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Nim-Benzyl-L-histidine methyl ester dihydrochloride | Nim-Benzyl-L-histidine methyl ester dihydrochloride. Group: Biochemicals. Alternative Names: L-His(Bzl)-OMe·2HCl. Grades: Highly Purified. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| Nim-Benzyl-L-histidine methyl ester dihydrochloride 98+% (TLC) | Nim-Benzyl-L-histidine methyl ester dihydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| Nimbic Acid | Nimbin derivative. A new limonoid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Nimbin | Nimbin is a intermediate limonoid isolated from Azadirachta. Nimbin prevents tau aggregation and increases cell viability. Nimbin is effective inhibits the envelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin can across blood-brain barrier. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NIMBIN;NIMBINH;(17α)-6α-Acetoxy-7α,15β:21,23-diepoxy-4β,8-dimethyl-1-oxo-18,24-dinor-11,12-seco-5α-chola-2,13,20,22-tetrene-4α,11-dicarboxylic acid dimethyl ester;18,24-Dinor-11,12-secochola-2,13,20,22-tetraene-4,11-dicarboxylic acid, 6-(acetyloxy)-7,15:21,23-diepoxy-4,8-dimethyl-1-oxo-, dimethyl ester, (4alpha,5alpha,6alpha,7alpha,15beta,17alpha)-;2H-Cyclopenta(B)naphtho(2,3-D)furan-10-acetic aci. Product Category: Inhibitors. Appearance: Powder. CAS No. 5945-86-8. Molecular formula: C30H36O9. Mole weight: 540.61. Purity: 0.98. IUPACName: nimbin. Canonical SMILES: CC1=C2C(CC1C3=COC=C3)OC4C2(C(C5(C(C4OC(=O)C)C(C=CC5=O)(C)C(=O)OC)C)CC(=O)OC)C. Density: 1.27g/cm³. ECNumber: 611-830-3. Product ID: ACM5945868. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Nimbin | A new limonoid. Group: Biochemicals. Alternative Names: (4α, 5α, 6α, 7α, 15 β,17α)-6-(Acetyloxy)-7,15:21,23-Diepoxy-4,8-dimethyl-1-oxo- 18,24-dinor-11,12-secochola-2,13,20,22-tetraene-4,11-dicarboxylic Acid Dimethyl Ester5- (Acetyloxy) -2- (3-furanyl) -3, 3a, 4a, 5, 5a, 6, 9, 9a, 10, 10a-decahydro-6- (methoxycarbonyl) -1, 6, 9a, 10a-tetramethyl-9-oxo-2H-cyclopenta [b]naphtho [2, 3-d]furan-10-acetic Acid. Grades: Highly Purified. CAS No. 5945-86-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Nimbin | Nimbin is a intermediate limonoid isolated from Azadirachta. Nimbin prevents tau aggregation and increases cell viability. Nimbin is effective inhibits the envelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin can across blood-brain barrier [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 5945-86-8. Pack Sizes: 1 mg. Product ID: HY-N3187. | |
| Nimbinic acid | Nimbinic acid. Group: Biochemicals. Alternative Names: (2R, 3aR, 4aS, 5R, 5aR, 6R, 9aR, 10R, 10aR) -2- (3-Furanyl) -3, 3a, 4a, 5, 5a, 6, 9, 9a, 10, 10a-decahydro-5-hydroxy-6- (methoxycarbonyl) -1, 6, 9a, 10a-tetramethyl-9-oxo-2H-cyclopenta [b]naphtho [2, 3-d]furan-10-acetic acid. Grades: Highly Purified. CAS No. 5866-30-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C27H32O8. US Biological Life Sciences. | Worldwide |
| Nimbolide | Nimbolide, a natural triterpenoid present in the edible parts of the neem tree (Azadirachta indica), was found to be growth-inhibitory in human colon carcinoma HT-29 cells. Nimbolide treatment of cells at 2.5-0uM resulted in moderate to very strong growth inhibition. Group: Biochemicals. Alternative Names: (4α, 5α, 6α, 7α, 15 β,17α)-. Grades: Highly Purified. CAS No. 25990-37-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Nimbolide | Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica). Nimbolide induces apoptosis through inactivation of NF-κB. Nimbolide inhibits CDK4/CDK6 kinase activity. Nimbolide suppresses the NF-κB, Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 25990-37-8. Molecular formula: C27H30O7. Mole weight: 466.52. Purity: 0.98. IUPACName: methyl 2-[6-(furan-3-yl)-7,9,11,15-tetramethyl-12,16-dioxo-3,17-dioxapentacyclo[9.6.1.02,9.04,8.015,18]octadeca-7,13-dien-10-yl]acetate. Canonical SMILES: CC1=C2C(CC1C3=COC=C3)OC4C2(C(C5(C6C4OC(=O)C6(C=CC5=O)C)C)CC(=O)OC)C. Product ID: ACM25990378. Alfa Chemistry ISO 9001:2015 Certified. | |
| Nimbolide (4a,5a,6a,7a,15b,17a)-7,15:21,23-Diepoxy-6-hydroxy-4,8-dimethyl-1-oxo-18,24-dinor-11,12-secochola-2,13,20,22-tetraene-4,11-dicarboxylic Acid g-lactone Methyl Ester, CCRIS 5723, NSC-309909) | A terpenoid lactone derived from Azadirachta indica (Neem tree) that displays a variety of biological activities including anti-malarial and anticancer activity. Recently it has also been shown that nimbolide sensitizes colon cancer cells to TRAIL-induced apoptosis through three distinct mechanisms: reactive oxygen species and ERK-mediated up-regulation of DR5 and DR4, downregulation of cell survival proteins, and up-regulation of pro-apoptotic proteins p53 and Bax. Group: Biochemicals. Grades: Highly Purified. CAS No. 25990-37-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Nimesulide | Nimesulide. Group: Biochemicals. Grades: Purified. CAS No. 51803-78-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Nimesulide | Nimesulide is a selective COX-2 inhibitor, with IC 50 s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC 50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R805. CAS No. 51803-78-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0363. | |
| Nimesulide | Nimesulide is a selective COX-2 inhibitor. Synonyms: N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide. Grades: > 95%. CAS No. 51803-78-2. Molecular formula: C13H12N2O5S. Mole weight: 308.3. | |
| Nimesulide | 5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C13H12N2O5S. CAS No. 51803-78-2. Prepack ID 39056848-5g. Molecular Weight 308.31. See USA prepack pricing. |  |
| Nimesulide Analog, Compound 76 - CAS 1021926-22-6 | A cell-permeable sulfonanilide that is shown to exhibit an antiproliferative effect against SKBR-3, BT474 and MDA-MB-453, and affects MCF-7 and MDA-MB-231 only at much higher concentrations. Group: Fluorescence/luminescence spectroscopy. | |
| Nimesulide-D5 | Nimesulide-D5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1330180-22-7. Molecular formula: C13H7D5N2O5S. Mole weight: 313.34. Catalog: APB1330180227. | |
| Nimesulide Impurity A | An impurity of Nimesulide, which is a selective COX-8 inhibitor. Synonyms: N-(2,4-Dinitro-6-phenoxyphenyl)methanesulfonamide; N-(2,4-Dinitro-6-phenoxyphenyl)methanesulphonamide. Grades: > 95%. CAS No. 51765-56-1. Molecular formula: C13H11N3O7S. Mole weight: 353.31. | |
| Nimesulide Impurity B | An impurity of Nimesulide, which is a selective COX-6 inhibitor. Synonyms: N-(2-Phenoxyphenyl)methanesulphonamide;N-(2-Phenoxyphenyl)methanesulphonamide; N-(2-phenoxyphenyl)methanesulfonamide; (2-Phenoxy)Methylsulfonylaniline. Grades: > 95%. CAS No. 51765-51-6. Molecular formula: C13H13NO3S. Mole weight: 263.32. | |
| Nimesulide Impurity D | An impurity of Nimesulide, which is a selective COX-3 inhibitor. Synonyms: 4-Nitro-2-phenoxyaniline; 4-Nitro-2-phenoxybenzenamine; 2-Amino-5-nitrodiphenyl Ether; 2-Phenoxy-4-nitroaniline. Grades: > 95%. CAS No. 5422-92-4. Molecular formula: C12H10N2O3. Mole weight: 230.23. | |
| Nimesulide Impurity E | An impurity of Nimesulide, which is a selective COX-7 inhibitor. Synonyms: N-(Methylsulfonyl)-4-(desnitro) Nimesulide; N-(Methylsulfonyl)-N-(2-phenoxyphenyl)methanesulfonamide. Grades: > 95%. CAS No. 905858-63-1. Molecular formula: C14H15NO5S2. Mole weight: 341.41. | |
| Nimesulide Impurity F | An impurity of Nimesulide, which is a selective COX-5 inhibitor. Synonyms: N-Methylsulfonyl Nimesulide; N-(Methylsulfonyl)-N-(4-nitro-2-phenoxyphenyl)methanesulfonamide; N-(Methylsulfonyl)-4'-nitro-2'-phenoxymethanesulfonanilide. Grades: > 95%. CAS No. 51765-72-1. Molecular formula: C14H14N2O7S2. Mole weight: 386.4. | |
| Nimesulide Impurity G | An impurity of Nimesulide, which is a selective COX-9 inhibitor. Synonyms: 4-Nitro-2-phenoxyphenol; Phenyl-(5-nitro-2-hydroxy-phenyl)-aether. Grades: > 95%. CAS No. 70995-08-3. Molecular formula: C12H9NO4. Mole weight: 231.21. | |
| Nimesulide (N- (4-Nitro-2-phenoxyphenyl) methanesulfonamide) | Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production. Group: Biochemicals. Alternative Names: N- (4-Nitro-2-phenoxyphenyl) methanesulfonamide. Grades: Highly Purified. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| N(Im)-ethoxycarbonyl-S-ethoxycarbonyl L-ergothioneine methyl ester iodide | N(Im)-ethoxycarbonyl-S-ethoxycarbonyl L-ergothioneine methyl ester iodide. Group: Biochemicals. Alternative Names: (S)-1-(Ethoxycarbonyl)-2-[(ethoxycarbonyl)thio]-a-(methoxycarbonyl)-N,N,N-trimethyl-1H-imidazole-4-ethanaminium iodide. Grades: Highly Purified. CAS No. 162240-57-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C16H26IN3O6S. US Biological Life Sciences. | Worldwide |
| N(Im)-Ethoxycarbonyl-S-ethoxycarbonyl N-Desmethyl L-Ergothioneine-d6 Methyl Ester | Intermediate in the production of labeled L-Ergothioneine. Group: Biochemicals. Alternative Names: 1-(Ethoxycarbonyl)-2-[(ethoxycarbonyl)thio]-N,N-dimethyl-L-histidine-d6 Methyl Ester. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Nimodipine | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C21H26N2O7. CAS No. 66085-59-4. Prepack ID 18892332-1g. Molecular Weight 418.44. See USA prepack pricing. | |
| Nimodipine | Nimodipine. Group: Biochemicals. Grades: Purified. CAS No. 66085-59-4. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Nimodipine | Nimodipine (BAY-e 9736) is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist. Nimodipine can be used for the research of cerebrovascular disorders [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-e 9736. CAS No. 66085-59-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0265. | |
| Nimodipine | Nimodipine is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy. Uses: Antihypertensive agents. Synonyms: LY127809; LY 127809; LY-127809; Nimodipine, Nimotop, Periplum, BAY E 9736, BAY-E-9736, BAYE9736. Grades: >98%. CAS No. 66085-59-4. Molecular formula: C21H26N2O7. Mole weight: 418.44. | |
| Nimodipine | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Nimodipine (Bay e 9736, Admon, Nimotop, periplum) | Used as a cerebral vasodilator. A dihydropyridine calcium channel blocker. Group: Biochemicals. Alternative Names: Bay e 9736, Admon, Nimotop, periplum. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Nimodipine - CAS 66085-59-4 | An L-type Ca2+ channel blocker. Group: Fluorescence/luminescence spectroscopy. | |
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