A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Parmodulin 2 (ML161) is an allosteric inhibitor of protease-activated receptor 1 (PAR1) with an IC50 of 0.26 ?M[1]. Parmodulin 2 is a potent and non-competitive inhibitor of SFLLRN-induced P-selectin expression leading to inhibition of platelet aggregation in vitro and platelet thrombus formation in vivo[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ML161. CAS No. 423735-93-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13965.
paromamine 6'-oxidase
Contains FAD. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Works in combination with EC 2.6.1.93, neamine transaminase, to replace the 6'-hydroxy group of paromamine with an amino group. The enzyme from the bacterium Streptomyces fradiae also catalyses EC 1.1.3.44, 6'''-hydroxyneomycin C oxidase. Group: Enzymes. Synonyms: btrQ (gene name); neoG (gene name); kanI (gene name); tacB (gene name); neoQ (obsolete gene name). Enzyme Commission Number: EC 1.1.3.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0416; paromamine 6'-oxidase; EC 1.1.3.43; btrQ (gene name); neoG (gene name); kanI (gene name); tacB (gene name); neoQ (obsolete gene name). Cat No: EXWM-0416.
Paromomycin
It is produced by the strain of Streptomyces rimosus var. paromomycinus. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. It has a role as an antibacterial drug, an antiprotozoal drug, an anthelminthic drug and an antiparasitic agent. Synonyms: Neomycin Sulfate EP Impurity E; Neomycin Impurity E; Framycetin Sulfate EP Impurity E; Neomycin B sulfate EP Impurity E; Catenulin; Aminosidin; Hydroxymycin; Zygomycin A1; Crestomycin; Paucimycin; Estomycin; Monomycin A; Paromomycin I; O-2,6-Diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine; Zygomycin A; Aminosidine; Aminosidine I; Amminosidin; Antibiotic 2230D; Antibiotic 503-3; Antibiotic SF 767B; Gabbromicina; Gabbromycin; Gabromycin; Humycin; Neomycin E; Paromomycin; Paromomycine; Quintomycin C; R 400. Grade: ≥95%. CAS No. 7542-37-2. Molecular formula: C23H45N5O14. Mole weight: 615.63.
Paromomycin II
It is produced by the strain of Str. rimosus forma paromomycinus NRRL 2455. It's an aminoglycoside antibiotic. It has activity against gram-positive, negative bacteria, mycobacterium and protozoa. It has good curative effect for amebic dysentery and a few bacillary dysentery. Synonyms: Neomycin Sulfate EP Impurity F; Neomycin Impurity F; Framycetin sulfate EP Impurity F; Neomycin B sulfate EP Impurity F; 4-O-(2-Amino-2-deoxy-α-D-glucopyranosyl)-2-deoxy-5-O-[3-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-β-D-ribofuranosyl]-D-streptamine; Neomycin F; O-2-Amino-2-deoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-D-streptamine; O-2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine; Paromomycin II; Aminosidin II; Aminosidine II; Zygomycin A2. Grade: ≥95%. CAS No. 51795-47-2. Molecular formula: C23H45N5O14. Mole weight: 615.63.
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C23H45N5O14. CAS No. 1263-89-4. Prepack ID 50313944-5g. Molecular Weight 615.63. See USA prepack pricing.
Paromomycin sulfate
Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Aminosidine sulfate. CAS No. 1263-89-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0956.
Paromomycin Sulfate
Aminogycoside antibiotic designed to fight intestinal infections such as cryptosporidiosis, amoebiasis, and leishmaniasis. Its antiprotozoal activity makes it an effecive histomonostatic feed additive in turkey poults experimentally infected with Histomonas meleagridis. Group: Biochemicals. Alternative Names: O-2,6-Diamino-2,6-dideoxy- β-L-idopyranosyl-(1?3)-O- β-D-ribofuranosyl-(1?5)-O-[2-amino-2-deoxy-α-D-glucopyranosyl-(1?4)]-2-deoxy-D-Streptamine Sulfate; O-2-Amino-2-deoxy-α-D-glucopyranosyl-(1?4)-O-[O-2,6-diamino-2,6-dideoxy- β-L-idopyranosyl-(1?3)- β-D-ribofuranosyl-(1?5)]-2-deoxy-D-streptamine Sulfate; 1600 Antibiotic; Aminosidin Sulfate; Aminosidine Sulfate; Aminoxidin; FI 5853; Farmiglucin; Farminosidin; Gabbroral; Humagel; Humatin; Humycin Sulfate; Paramicina; Pargonyl; Paricina; Sinosid. Grades: Highly Purified. CAS No. 1263-89-4. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C??H??N?O?? xH?SO?, Molecular Weight: 615.63 free acid. US Biological Life Sciences.
Worldwide
Paromomycin Sulfate
Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Paromomycin sulfate salt. Product Category: Inhibitors. CAS No. 1263-89-4. Molecular formula: C23H47N5O18S. Mole weight: 713.7. Purity: ≥98.0%. Product ID: ACM1263894. Alfa Chemistry ISO 9001:2015 Certified.
Paromomycin Sulfate ≥675ug/mg USP
Aminogycoside antibiotic designed to fight intestinal infections such as cryptosporidiosis, amoebiasis, and leishmaniasis. Its antiprotozoal activity makes it an effecive histomonostatic feed additive in turkey poults experimentally infected with Histomonas meleagridis. Group: Biochemicals. Alternative Names: O-2,6-Diamino-2,6-dideoxy- β-L-idopyranosyl-(1?3)-O- β-D-ribofuranosyl-(1?5)-O-[2-amino-2-deoxy-α-D-glucopyranosyl-(1?4)]-2-deoxy-D-Streptamine Sulfate; O-2-Amino-2-deoxy-α-D-glucopyranosyl-(1?4)-O-[O-2,6-diamino-2,6-dideoxy- β-L-idopyranosyl-(1?3)- β-D-ribofuranosyl-(1?5)]-2-deoxy-D-streptamine Sulfate; 1600 Antibiotic; Aminosidin Sulfate; Aminosidine Sulfate; Aminoxidin; FI 5853; Farmiglucin; Farminosidin; Gabbroral; Humagel; Humatin; Humycin Sulfate; Paramicina; Pargonyl; Paricina; Sinosid. Grades: USP. CAS No. 1263-89-4. Pack Sizes: 1g, 5g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
Paroxetine
Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs). Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL29060. CAS No. 61869-08-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-122272.
Paroxetine EP Impurity A
Paroxetine EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1322626-23-2. Molecular formula: C19H21NO3. Mole weight: 311.38. Catalog: APB1322626232.
Paroxetine EP Impurity C
Paroxetine EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 105813-14-7. Molecular formula: C26H26FNO3. Mole weight: 419.5. Catalog: APB105813147.
Paroxetine EP Impurity C HCl
Paroxetine EP Impurity C HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 105813-13-6. Molecular formula: C26H27ClFNO3. Mole weight: 455.95. Catalog: APB105813136.
Paroxetine EP Impurity E
Paroxetine EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 105813-05-6. Molecular formula: C19H20FNO3. Mole weight: 329.37. Catalog: APB105813056.
Paroxetine EP Impurity F
Paroxetine EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 105813-40-9. Molecular formula: C26H27NO3. Mole weight: 401.5. Catalog: APB105813409.
Paroxetine EP Impurity F HCl
Paroxetine EP Impurity F HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 105813-39-6. Molecular formula: C26H28ClNO3. Mole weight: 437.96. Catalog: APB105813396.
Paroxetine EP Impurity G HCl
Paroxetine EP Impurity G HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1012886-75-7. Molecular formula: C12H15ClFN. Mole weight: 227.71. Catalog: APB1012886757.
Paroxetine EP Impurity I
Paroxetine EP Impurity I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125224-43-3. Molecular formula: C12H16FNO. Mole weight: 209.26. Catalog: APB125224433.
Paroxetine hydrochloride
Paroxetine hydrochloride is a potent selective serotonin-reuptake inhibitor, commonly prescribed as an GRK2 inhibitor with IC 50 of 14?μM. Paroxetine hydrochloride can be used for the research of depressive disorder [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL29060 hydrochloride; BRL29060A. CAS No. 78246-49-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0492.
Paroxetine hydrochloride
Paroxetineis a selective serotonin reuptake inhibitor (SSRI). It is used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms. Uses: Cytochrome p-450 cyp2d6 inhibitors. Synonyms: Win 47203; Win-47203; Win47203. Grade: >98%. CAS No. 78246-49-8. Molecular formula: C19H21ClFNO3. Mole weight: 365.83.
Paroxetine hydrochloride
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Paroxetine Hydrochloride
Paroxetine is a phenylpiperidine derivative that potently and selectively inhibits the reuptake of serotonin, blocking the human serotonin transporter with a Ki value of 0.72nM.1 It less effectively blocks the human norepinephrine and dopamine transporters (Ki = 440 and 1,900nM, respectively).1 Paroxetine also inhibits, at concentrations in excess of 1uM, nitric oxide synthase activity in the cytosol of hamster brain.2 Selective serotonin uptake inhibitors, including paroxetine, are used in cases of depression and anxiety disorder.3,4. Group: Biochemicals. Alternative Names: (3S-trans) -3-[ (1, 3-Benzodioxol-5-yloxy) methyl]-4- (4-fluorophenyl) piperidine Hydrochloride; Aropax; Deroxat; Paxil; Seroxat. Grades: Highly Purified. CAS No. 78246-49-8. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C19H20FNO3·HCl, Molecular Weight: 365.83. US Biological Life Sciences.
A selective serotonin reuptake inhibitor. Used as an antidepressant. Group: Biochemicals. Alternative Names: (3S-trans) -3-[ (1, 3-Benzodioxol-5-yloxy) methyl]-4- (4-fluorophenyl) piperidine, FG-7051, BRL-29060. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
A very potent uptake inhibitor highly selective for 5-HT transporter (Ki = 0.065nM and 0.05nM for human and rat 5-HT transporters, respectively). A popular antidepressant drug of the SSRI type. Used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms. Group: Biochemicals. Grades: Highly Purified. CAS No. 110429-35-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Paroxetine hydrochloride hemihydrate
Paroxetine hydrochloride hemihydrate is a potent selective serotonin-reuptake inhibitor, commonly prescribed as an antidepressant and has GRK2 inhibitory ability with IC 50 of 14?μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL29060 hydrochloride hemihydrate; BRL29060A hemihydrate. CAS No. 110429-35-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0492A.
Paroxetine hydrochloride hemihydrate
25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H20FNO3 ·HCl ·0.5H2O. CAS No. 110429-35-1. Prepack ID 43946554-25mg. Molecular Weight 374.83. See USA prepack pricing.
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Paroxetine Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Paroxetine Related Compound D
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Paroxetine Related Compound E Mixture
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Paroxetine Related Compound F
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Paroxetine Related Compound G
United States Pharmacopeia (USP) Reference Standard, ~21% povidone. Group: Pharmacopeia & metrological institutes standards.
Paroxetine System Suitability Mixture A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Paroxol Methanesulfonate
An intermediate in the synthesis of Paroxetine, a selective serotonin reuptake inhibitor. Group: Biochemicals. Alternative Names: (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol Methanesulfonate. Grades: Highly Purified. CAS No. 608521-21-7. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Paroxol tosylate
Paroxol tosylate. Group: Biochemicals. Alternative Names: (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol tosylate; (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol 3- (4-methyl Benzene sulfonate) . Grades: Highly Purified. CAS No. 317323-77-6. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C20H24FNO3S. US Biological Life Sciences.
Worldwide
Paroxol Tosylate.
Piperidine derivative intermediate for paroxetin preparation. Group: Biochemicals. Alternative Names: (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol Tosylate; (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol 3- (4-Methyl Benzene sulfonate) . Grades: Highly Purified. CAS No. 317323-77-6. Pack Sizes: 25mg. US Biological Life Sciences.
PARP10-IN-2 is a potent mono?ADP?ribosyltransferase PARP10 inhibitor with an IC 50 of 3.64 μM for human PARP10. PARP10-IN-2 reveals potent inhibition on PARP2 and PARP15 with IC 50 s of 27 μM and 11 μM for human PARP2 and human PARP15, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1042780-52-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148753.
PARP10-IN-3
PARP10-IN-3 is a selective mono?ADP?ribosyltransferase PARP10 inhibitor with an IC 50 of 480 nM for human PARP10. PARP10-IN-3 reveals potent inhibition on PARP2 and PARP15 with IC 50 s of 1.7 μM for human PARP2 and human PARP15, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2225800-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148754.
PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC 50 value of 0.082 μM. PARP1-IN-11 shows complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1 and TNKS2 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2482484-87-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147886.
PARP-1-IN-2
PARP-1-IN-2 (compound 11g) is a potent and BBB-penetrated PARP1 inhibitor, with an IC 50 of 149 nM. PARP1-IN-2 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549. PARP1-IN-2 can induce A549 cells apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 684234-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-147027.
PARP1-IN-29
PARP1-IN-29 is an orally active PARP-1 inhibitor with an IC 50 value of 6.3 nM. PARP1-IN-29, after being labeled with [18F], can be used for positron emission tomography (PET) imaging, specifically targeting PARP-1 in tumors. PARP1-IN-29 is applicable in the fields of oncology and imaging research, particularly for detecting PARP-1 activity in cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1567375-93-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-164475.
PARP-1-IN-3
PARP-1-IN-3, a benzamide derivative, is a potent PARP-1 inhibitor with IC 50 values of 0.25 nM and 2.34 nM for PARP-1 and PARP-2, respectively. PARP-1-IN-3 induces apoptosis and arrest cell cycle at G2/M phase. PARP-1-IN-3 can be used in research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2976342-33-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-149800.
PARP1-IN-31
PARP1-IN-31 (compound 11f) is a phthalazinone-based compound, an anti-lung adenocarcinoma compound with inhibitory activity against PARP-1 ( IC 50 value of 97 nM), inducing apoptosis and inhibiting cell proliferation in lung cancer cell lines. Uses: Scientific research. Group: Signaling pathways. CAS No. 684234-60-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-164713.
PARP1-IN-33
PARP1-IN-33 (Example 6) is a PARP1 inhibitor ( IC 50 : 0.41 nM). PARP1-IN-33 has retinal cytoprotective effect, with an EC 50 of 0.02 nM (inhibition on MTS activity of H 2 O 2 induced human retinal pigment epithelial cell) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2640677-68-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164926.
PARP-1-IN-4
PARP-1-IN-4 is a PARP-1 inhibitor. PARP-1-IN-4 has inhibitory activity against PARP-1 with IC 50 value of 302 μM. PARP-1-IN-4 can be used for the research of lung adenocarcinoma [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 684234-56-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153590.
PARP1-IN-8
PARP1-IN-8 (compound 11c) is a potent and BBB-penetrated PARP1 inhibitor, with an IC 50 of 97 nM. PARP1-IN-8 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 836640-15-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-147030.
PARP7-IN-15 (Compound 18) is a PARP7 inhibitor with IC 50 of 0.56 nM, that has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2819998-97-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155351.
The PARP Inhibitor III, DPQ, also referenced under CAS 129075-73-6, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy.
PARP Inhibitor IV, IQD - CAS 1188540
The PARP Inhibitor IV, IQD, also referenced under CAS 1188540, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy.