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Sophocarpine is an alkaloid from Chinese medicinal plant Sophora alopecuroides. The compound is a low potency blocker of hERG channels and is able to shift the inactivation curve of cardiac action potential. It was shown to be anti-nociceptive agent since it has central and peripheral analgesic properties. Sophocarpine is an anti-inflammatory compound and excerts its activity via NF-κB and MAPKs inactivation. Group: Other alkaloids. CAS No. 6483-15-4. Molecular formula: C15H22N2O. Mole weight: 246.35 g/mol. Canonical SMILES: C1C[C@H]2CN3[C@H] (CC=CC3=O)[C@@H]4[C@H]2N (C1)CCC4. Catalog: ACM6483154.
Sophocarpine
Sophocarpine is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. Sophocarpine significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy , activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Sophocarpine has been demonstrated to have anti-tumor activity in various cancer cells, including hepatocellular carcinoma, prostate cancer and colorectal cancer [1]. Uses: Scientific research. Group: Natural products. CAS No. 6483-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0103.
Sophocarpine
Sophocarpine. Group: Biochemicals. Alternative Names: 13,14-Didehydromatridin-15-one, 9CI. Grades: Plant Grade. CAS No. 6483-15-4,145572-44-7. Pack Sizes: 20mg. Molecular Formula: C15H22N2O, Molecular Weight: 246.348. US Biological Life Sciences.
Worldwide
Sophocarpine monohydrate
Sophocarpine (monohydrate) is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. Sophocarpine (monohydrate) significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy , activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Sophocarpine (monohydrate) has been demonstrated to have anti-tumor activity in various cancer cells, including hepatocellular carcinoma, prostate cancer and colorectal cancer [1]. Uses: Scientific research. Group: Natural products. CAS No. 145572-44-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0103A.
Sophoflavescenol
Sophoflavescenol is a compound of the flavonoid class found in the roots of Sophora flavescens Ait. Sophoflavescenol is a PDE5 inhibitor with antioxidant and anti-inflammatory properties. Synonyms: 3,7-dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)chromen-4-one. Grades: >98%. CAS No. 216450-65-6. Molecular formula: C21H20O6. Mole weight: 368.385.
Sophoflavescenol
Sophoflavescenol. Group: Biochemicals. Grades: Plant Grade. CAS No. 216450-65-6. Pack Sizes: 5mg. Molecular Formula: C21H20O6, Molecular Weight: 368.38. US Biological Life Sciences.
Worldwide
Sophorabioside
Sophorabioside. Group: Biochemicals. CAS No. 2945-88-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Sophorabioside
Sophorabioside is a compound of the flavonoid class found in the seeds of Sophora japonica. Synonyms: 3-[4-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxyphenyl]-5,7-dihydroxychromen-4-one. Grades: >98%. CAS No. 2945-88-2. Molecular formula: C27H30O14. Mole weight: 578.523.
Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties. Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Kushenol F. CAS No. 97938-30-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N1231.
Sophora Flavescens P.E. 5:1
Sophora Flavescens P.E. 5:1.
CA, FL & NJ
Sophoraflavonoloside
Sophoraflavonoloside. Group: Biochemicals. CAS No. 19895-95-5. Pack Sizes: 5mg. US Biological Life Sciences.
Sophoranol is an alkaloid that can be isolated from S. flavescens, with antiviral activity. Sophoranol has anti-HBV (hepatitis B virus) activity. Sophoranol shows potent antiviral activities against respiratory syncytial virus (RSV)with an IC50 of 10.4 μg/mL. Group: Inhibitors. Alternative Names: 5-Hydroxymatridine-15-one. CAS No. 3411-37-8. Molecular formula: C15H24N2O2. Mole weight: 264.36. Purity: 95%+. Canonical SMILES: O=C1CCC[C@]2 ([H])[C@@]3 ([H])CCCN4[C@@]3 ([H])[C@] (CCC4) (O)CN21. Density: 1.25. Catalog: ACM3411378.
Sophora Root Extract
Sophora root extract is prepared from the sophora flavescens, a species of plant in the genus sophora. Matrine is the major alkaloid component found in sophora root extract. Sophora root extract is commonly used for the treatment of viral hepatitis, enteritis, cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases. Group: Others. Mole weight: 248.37. Sophora Root Extract; Sophora Flavescens Alt. Cat No: EXTC-019.
Sophoricoside
Sophoricoside. Group: Biochemicals. Alternative Names: Genistein 4?-glucoside. Grades: Plant Grade. CAS No. 152-95-4. Pack Sizes: 20mg. Molecular Formula: C21H20O10, Molecular Weight: 432.377999999999. US Biological Life Sciences.
Worldwide
Sophoricoside
Sophoricoside - Product ID: NST-10-40. Category: Flavonoids. Alternative Names: Genistein-4'-O-glucoside. Purity: 98%. Test method: HPLC. CAS No. 152-95-4. Pack Sizes: 10g, 20g, 50g, 100g. Appearance: White to beige coloured Powder. Molecular formula: C21H20O10. Mole weight: 432.38. Storage: +2 +8 °C.
Sophoricoside
Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects. Uses: Scientific research. Group: Natural products. CAS No. 152-95-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0423.
Sophoridine
Sophoridine. Group: Biochemicals. Grades: Plant Grade. CAS No. 6882-68-4. Pack Sizes: 20mg. Molecular Formula: C15H24N2O, Molecular Weight: 248.36. US Biological Life Sciences.
Worldwide
Sophorose monohydrate
Sophorose (2-O-beta-D-Glucopyranosyl-D-glucopyranose) monohydrate is the disaccharide component of microbial glycolipids, which are often used as biosurfactants due to their hydrophobicity. Sophorolipids also exhibit antibacterial, antifungal, spermicidal, virucidal, and anticancer activities. In studies of Trichoderma reesei fermentation, sophorose monohydrate has been identified as a potent inducer of cellulase gene expression [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 2-O-beta-D-Glucopyranosyl-D-glucopyranose monohydrate. CAS No. 140686-17-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-119445A.
Soquelitinib
Soquelitinib (CPI-818) is an orally active and highly selective covalent interleukin-2-inducible kinase ( ITK ) inhibitor. Soquelitinib is active in six different models of T cell-mediated inflammatory and immune disease, including acute and chronic asthma, pulmonary fibrosis, systemic sclerosis (scleroderma), psoriasis, and acute graft versus host disease with Th2 cytokine product inhibition. Soquelitinib increases tumor infiltration of normal CD8 + cells that possess enhanced T effector function [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPI-818. CAS No. 2226636-04-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150298.
Sorafenib
Sorafenib (Bay 43-9006) is a potent and orally active Raf inhibitor with IC 50 s of 6 nM and 20 nM for Raf-1 and B-Raf , respectively. Sorafenib is a multikinase inhibitor with IC 50 s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2 , VEGFR3 , PDGFRβ , FLT3 and c-Kit , respectively. Sorafenib induces autophagy and apoptosis. Sorafenib has anti-tumor activity. Sorafenib is a ferroptosis activator [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bay 43-9006. CAS No. 284461-73-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-10201.
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4- [4- [ [ [ [2-Chloro-3- (trifluoromethyl) ?phenyl] ?amino] ?carbonyl] ?amino] ?phenoxy] ?-N-methyl-2-pyridinecarboxamide; 4-Deschloro-2-chloro-Sorafenib. Grades: > 95%. CAS No. 1431697-81-2. Molecular formula: C21H16ClF3N4O3. Mole weight: 464.83.
Sorafenib β-D-Glucuronide
Sorafenib β-D-Glucuronide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1130164-93-0. Molecular Formula: C27H24ClF3N4O9. Mole Weight: 640.95. Catalog: APB1130164930.
Sorafenib-beta-D-Glucuronide
Sorafenib-beta-D-Glucuronide is one of Sorafenib metabolites. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: N-[4-Chloro-3-(trifluoromethyl)phenyl]-N-[(4-{[2-(methylcarbamoyl)pyridin-4-yl]oxy}phenyl)carbamoyl]-beta-D-glucopyranuronosylamine; 1- [ [4-Chloro-3- (trifluoroMethyl) phenyl] [ [ [4- [ [2- [ (MethylaMino) carbonyl] -4-pyridinyl] oxy] phenyl] aMino] carbonyl] aMino] -1-deoxy-Beta-D-glucopyranuronic Acid; Sorafenib Beta-D-Glucuronide. Grades: ≥95%. CAS No. 1130164-93-0. Molecular formula: C27H24ClF3N4O9. Mole weight: 640.95.
Sorafenib Hemitosylate is the salt of Sorafenib, which is a kinase inhibitor drug used for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4-[4-[[[[4-chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino] phenoxy]-N-methyl-2-pyridinecarboxamide, 4-methylbenzenesulfonate (2:1). CAS No. 2056030-06-7. Molecular formula: C21H16ClF3N4O3.1/2(C7H8O3S). Mole weight: 550.92.
Sorafenib Hemi-Tosylate
Sorafenib Hemi-Tosylate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2056030-06-7. Molecular Formula: C21H16ClF3N4O3· 1/2 C7H8O3S. Mole Weight: 550.93. Catalog: APB2056030067.
Sorafenib Impurity 1
Sorafenib Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 99586-65-9. Molecular Formula: C6H5ClN2O. Mole Weight: 156.57. Catalog: APB99586659.
Sorafenib Impurity 1
Sorafenib Impurity 1 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Molecular formula: C28H25N7O6. Mole weight: 555.54.
Sorafenib Impurity 10
Sorafenib Impurity 10 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: SORAFENIB IMPURITY 10; 2206827-14-5; propan-2-yl N-[4-[2-(methylcarbamoyl)pyridin-4-yl]oxyphenyl]carbamate; SORAFENIBIMPURITY10; EN300-6494528; Z3064469246; Isopropyl 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]phenylcarbamate; propan-2-yl N-(4-{[2-(methylcarbamoyl)pyridin-4-yl]oxy}phenyl)carbamate. Molecular formula: C24H24F3N5O4. Mole weight: 503.47.
Sorafenib Impurity 10
Sorafenib Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 284461-82-1. Molecular Formula: C22H18ClF3N4O3. Mole Weight: 478.86. Catalog: APB284461821.
Sorafenib Impurity 11
Sorafenib Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1290546-48-3. Molecular Formula: C21H16ClF3N4O3. Mole Weight: 464.83. Catalog: APB1290546483.
Sorafenib Impurity 11073
Sorafenib Impurity 11073. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2090542-70-2. Molecular Formula: C7H7FN2O3. Mole Weight: 186.14. Catalog: APB2090542702.
Sorafenib Impurity 13
Sorafenib Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 583840-04-4. Molecular Formula: C20H14ClF3N4O4. Mole Weight: 466.8. Catalog: APB583840044.
Sorafenib Impurity 14
Sorafenib Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2206827-14-5. Molecular Formula: C17H19N3O4. Mole Weight: 329.36. Catalog: APB2206827145.
Sorafenib Impurity 15
Sorafenib Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 871555-75-8. Molecular Formula: C14H9ClF3NO2. Mole Weight: 315.68. Catalog: APB871555758.
Sorafenib Impurity 16
Sorafenib Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2206827-12-3. Molecular Formula: C16H17N3O4. Mole Weight: 315.33. Catalog: APB2206827123.
Sorafenib Impurity 17
Sorafenib Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 53750-66-6. Molecular Formula: C6H3Cl2NO. Mole Weight: 176. Catalog: APB53750666.
Sorafenib Impurity 22
Sorafenib Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 777-37-7. Molecular Formula: C7H3ClF3NO2. Mole Weight: 225.55. Catalog: APB777377.
Sorafenib Impurity 24
Sorafenib Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 39974-35-1. Molecular Formula: C7H3ClF3NO2. Mole Weight: 225.55. Catalog: APB39974351.
Sorafenib Impurity 27
Sorafenib Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 583840-03-3. Molecular Formula: C21H16ClF3N4O4. Mole Weight: 480.83. Catalog: APB583840033.
Sorafenib Impurity 31
Sorafenib Impurity 31. Uses: For analytical and research use. Group: Impurity standards. CAS No. 62476-58-8. Molecular Formula: C7H5ClF3N. Mole Weight: 195.57. Catalog: APB62476588.
Sorafenib Impurity 4
Sorafenib Impurity 4 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Molecular formula: C7H7NO2. Mole weight: 137.14.
Sorafenib Impurity 43
Sorafenib Impurity 43. Uses: For analytical and research use. Group: Impurity standards. CAS No. 757251-59-5. Molecular Formula: C13H12N2O3. Mole Weight: 244.25. Catalog: APB757251595.
Sorafenib Impurity 5
Sorafenib Impurity 5 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Molecular formula: C14H13ClN4O2. Mole weight: 304.73.
Sorafenib Impurity 5 (Regorafenib Impurity 5)
Sorafenib Impurity 5 (Regorafenib Impurity 5). Uses: For analytical and research use. Group: Impurity standards. CAS No. 320-51-4. Molecular Formula: C7H5ClF3N. Mole Weight: 195.57. Catalog: APB320514.
Sorafenib Impurity 6
Sorafenib Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2204442-52-2. Molecular Formula: C27H23N5O6. Mole Weight: 513.51. Catalog: APB2204442522.
Sorafenib Impurity 7
Sorafenib Impurity 7 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: 4-Hydroxy-phenylhydroxylamine. Grades: ≥ 95%. CAS No. 3505-87-1. Molecular formula: C6H7NO2. Mole weight: 125.13.
Sorafenib Impurity 73
Sorafenib Impurity 73. Uses: For analytical and research use. Group: Impurity standards. CAS No. 862875-16-9. Molecular Formula: C21H17F3N4O4. Mole Weight: 446.39. Catalog: APB862875169.
Sorafenib Impurity 8
Sorafenib Impurity 8 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: Flucofuron; 370-50-3; Flucofuron [ISO]; TCMDC-137559; 1,3-bis[4-chloro-3-(trifluoromethyl)phenyl]urea; CHEBI:59242; 1,3-Bis(4-chloro-alpha,alpha,alpha-trifluoro-m-tolyl)urea; 1,3-bis(4-chloro-3-(trifluoromethyl)phenyl)urea; N,N'-bis[4-chloro-3-(trifluoromethyl)phenyl]urea; U3V3S70655; Mitin N; 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-chloro-3-(trifluoromethyl)phenyl)urea; N,N'-BIS(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)UREA. Molecular formula: C25H25F3N6O3. Mole weight: 514.50.
Sorafenib Impurity 84
Sorafenib Impurity 84. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1403469-80-6. Molecular Formula: C7H6Cl2N2O. Mole Weight: 205.04. Catalog: APB1403469806.
Sorafenib Impurity 85
Sorafenib Impurity 85. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1021077-12-2. Molecular Formula: C7H6Cl2N2O. Mole Weight: 205.04. Catalog: APB1021077122.
Sorafenib Impurity 86
Sorafenib Impurity 86. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1793080-72-4. Molecular Formula: C21H17F4N2O7P. Mole Weight: 516.34. Catalog: APB1793080724.
Sorafenib Impurity 87
Sorafenib Impurity 87. Uses: For analytical and research use. Group: Impurity standards. CAS No. 24484-93-3. Molecular Formula: C7H6ClNO2. Mole Weight: 171.58. Catalog: APB24484933.
Sorafenib Impurity 88
Sorafenib Impurity 88. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2004659-85-0. Molecular Formula: C13H12N2O2. Mole Weight: 228.25. Catalog: APB2004659850.
Sorafenib Impurity 9
Sorafenib Impurity 9 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: 4- (4- (3- (4-Hydroxy-3- (trifluoromethyl) phenyl) ureido) phenoxy) -N-methylpicolinamide. CAS No. 862875-16-9. Molecular formula: C21H17F3N4O4. Mole weight: 446.38.
Sorafenib Impurity C
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Grades: > 95%. Molecular formula: C27H23N5O6. Mole weight: 513.51.
Sorafenib Impurity G
Sorafenib Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate. CAS No. 18585-06-3. Molecular Formula: C10H9ClF3NO2. Mole Weight: 267.63. Catalog: APB18585063.
Sorafenib Impurity I
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 1,3-bis-(4-Chloro-α,α,α-trifluoro-m-tolyl)urea. Grades: > 95%. CAS No. 370-50-3. Molecular formula: C15H8Cl2F6N2O. Mole weight: 417.13.
Sorafenib Impurity INT-1-B
Sorafenib Impurity INT-1-B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 220000-87-3. Molecular Formula: C7H7ClN2O. Mole Weight: 170.6. Catalog: APB220000873.
Sorafenib Impurity INT-1-F
Sorafenib Impurity INT-1-F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1065074-98-7. Molecular Formula: C8H11N3O. Mole Weight: 165.2. Catalog: APB1065074987.
Sorafenib Impurity INT-1-N
Sorafenib Impurity INT-1-N. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1863331-80-9. Molecular Formula: C9H13N3O. Mole Weight: 179.22. Catalog: APB1863331809.
Sorafenib Impurity INT-1-O
Sorafenib Impurity INT-1-O. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C9H14N4O. Mole Weight: 194.24. Catalog: APB09538.