A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82385-42-0. Pack Sizes: 500 mg; 1 g. Product ID: HY-B1390B.
Saccharin sodium salt
Saccharin sodium salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 128-44-9. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C7H4NNaO3S. US Biological Life Sciences.
Worldwide
Saccharin sodium salt dihydrate
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Saccharin Sodium Salt Dihydrate
Saccharin Sodium Salt Dihydrate is a non-nutritive sweetener; pharmaceutic aid (flavor). Saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria for this listing. Group: Biochemicals. Grades: Highly Purified. CAS No. 6155-57-3. Pack Sizes: 5g, 25g. Molecular Formula: C7H4NNaO3S; 2(H2O). US Biological Life Sciences.
Worldwide
Saccharin USP
Saccharin USP. CAS No. 81-07-2. Molecular formula: C7H5NO3S.
Saccharocarcin A
An unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcin and versipelostatin; has pronounced activity against gram positive bacteria and chlamydia trachomatis; inhibits transcription from the promoter of GRP78; appears to target the phosphatidylinositide-3-kinase/akt signalling pathway. Synonyms: 10-[[4-(acetylamino)-2,4,6-trideoxy-3-C-methylhexopyranosyl]oxy]-4-[[O-2,6-dideoxyhexopyranosyl-(1?4)-O-2,6-dideoxy-3-O-(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)hexopyranosyl-(1?4)-2,6-dideoxyhexopyranosyl]oxy]-15-ethyl-2,3,4,4a,6a,9,10,12a,15,16,20a,20b-dodecahydro-21-hydroxy-1,3,7,9,11,20a-hexamethyl-18H-16a,19-metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione. Grades: >95% by HPLC. CAS No. 158475-32-2. Molecular formula: C67H101NO20. Mole weight: 1240.51.
Saccharocarcin A
Saccharocarcin A is an unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcin and versipelostatin which has pronounced activity against Gram positive bacteria and Chlamydia trachomatis. Limited availability has restricted further investigation of this metabolite in the literature. However, several members of this class have received considerable literature focus. Versipelostatin was shown to inhibit transcription from the promoter of GRP78, a gene that is activated as part of a stress signaling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action was seen only in conditions of glucose deprivation and caused selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signaling pathway. Group: Biochemicals. Grades: Highly Purified. CAS No. 158475-32-2. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Saccharocarcin B
Saccharocarcin B is an unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcins and versipelostatin which has pronounced activity against Gram positive bacteria and Chlamydia trachomatis. Limited availability has restricted further investigation of this metabolite in the literature. However, several members of this class have received considerable literature focus. Versipelostatin was shown to inhibit transcription from the promoter of GRP78, a gene that is activated as part of a stress signaling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action was seen only in conditions of glucose deprivation and caused selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signaling pathway. Group: Biochemicals. Grades: Highly Purified. CAS No. 158475-33-3. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Saccharocarcin B
An unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcin and versipelostatin; has pronounced activity against gram positive bacteria and chlamydia trachomatis; inhibits transcription from the promoter of GRP78; appears to target the phosphatidylinositide-3-kinase/akt signalling pathway. Synonyms: 10-[[4-(acetylamino)-2,4,6-trideoxy-3-C-methylhexopyranosyl]oxy]-4-[[O-2,6-dideoxyhexopyranosyl-(1?4)-O-2,6-dideoxy-3-O-(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)hexopyranosyl-(1?4)-2,6-dideoxyhexopyranosyl]oxy]-2,3,4,4a,6a,9,10,12a,15,16,20a,20b-dodecahydro-21-hydroxy-1,3,7,9,11,20a-hexamethyl-15-propyl-18H-16a,19-metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione. Grades: >99% by HPLC. CAS No. 158475-33-3. Molecular formula: C68H103NO20. Mole weight: 1254.54.
Saccharocin
Saccharocin is produced by the strain of Saccharopolyspora sp. AC-3440. It is effective against gram-positive and negative bacteria, and also against aminoglycoside antibiotic-resistant bacteria. Synonyms: KA-5685. CAS No. 86630-31-1. Molecular formula: C21H40N4O12. Mole weight: 540.56.
saccharolysin
An 83 kDa cytoplasmic thiol-dependent metalloendopeptidase from Saccharomyces cerevisiae. In peptidase family M3 (thimet oligopeptidase family). Group: Enzymes. Synonyms: proteinase yscD; yeast cysteine proteinase D (Misleading); Saccharomyces cerevisiae proteinase yscD. Enzyme Commission Number: EC 3.4.24.37. CAS No. 96779-48-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4319; saccharolysin; EC 3.4.24.37; 96779-48-5; proteinase yscD; yeast cysteine proteinase D (Misleading); Saccharomyces cerevisiae proteinase yscD. Cat No: EXWM-4319.
Saccharomyces boulardii is a tropical species of yeast first isolated from lychee and mangosteen fruit in 1923 by French scientist Henri Boulard. S. boulardii is sometimes used as a probiotic with the purpose of introducing beneficial microbes into the large and small intestines and conferring protection against pathogens. Applications: dietary supplements - capsules, powder, tablets. food - bars, powdered beverages. Group: Probiotics. Synonyms: Saccharomyces Boulardii Probiotics Powder; Saccharomyces Boulardii. Activity: 10 billion CFU/g or more. Stability: 24 Months. Appearance: White To Light Yellow-Colored, Free-Flowing Powder. Storage: Recommend storage at refrigeration (4 °C) or frozen temperature (-18 °C) in original, sealed package until processed. Form: Powder. Streptococcus Strains. Cat No: PRBT-053.
Saccharomycescerevisiae
Synonyms: TORULA YEAST; YEAST SACCHAROMYCES CEREVISIAE TYPE I; YEAST SACCHAROMYCES CEREVISIAE TYPE II; YEAST; YEAST BAKERS; YEAST BREWERS; YEAST, BREWER'S; BAKERS YEAST. Grades: dried. CAS No. 68876-77-7.
Saccharomyces Freeze Dried Powder
Saccharomyces is a genus of fungi that includes many species of yeasts. Saccharomyces is from Greek (sugar) and (mushroom) and means sugar fungus. Many members of this genus are considered very important in food production. It is known as the brewer's yeast or baker's yeast. They are unicellular and saprophytic fungi. One example is Saccharomyces cerevisiae, which is used in making wine, bread, and beer. Other members of this genus include the wild yeast Saccharomyces paradoxus that is the closest relative to S. cerevisiae, Saccharomyces bayanus, used in making wine, and Saccharomyces boulardii, used in medicine. Group: Others. Synonyms: Saccharomyces Freeze Dried Powder; Saccharomyces. Saccharomyces Freeze Dried Powder; Saccharomyces. Cat No: PRBT-038.
saccharopepsin
Located in the vacuole of the bakers yeast (Saccharomyces cerevisiae) cell. In peptidase family A1 (pepsin A family). Group: Enzymes. Synonyms: yeast endopeptidase A; Saccharomyces aspartic proteinase; aspartic proteinase yscA; proteinase A; proteinase yscA; yeast proteinase A; Saccharomyces cerevisiae aspartic proteinase A; yeast proteinase A; PRA. Enzyme Commission Number: EC 3.4.23.25. CAS No. 37228-80-1. Proteinase A. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4263; saccharopepsin; EC 3.4.23.25; 37228-80-1; yeast endopeptidase A; Saccharomyces aspartic proteinase; aspartic proteinase yscA; proteinase A; proteinase yscA; yeast proteinase A; Saccharomyces cerevisiae aspartic proteinase A; yeast proteinase A; PRA. Cat No: EXWM-4263.
Saccharopine
Saccharopine (L-Saccharopine), a lysine degradation intermediate, is a mitochondrial toxin. Lysine and α-ketoglutarate are converted into Saccharopine by the lysine-ketoglutarate reductase. Saccharopine is then oxidized to α-aminoapidate semialdehyde and glutamate by the saccharopine dehydrogenase. Saccharopine impairs development by disrupting mitochondrial homeostasis [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: L-Saccharopine. CAS No. 997-68-2. Pack Sizes: 1 mg. Product ID: HY-W040307.
The activities of this enzyme along with EC 1.5.1.8, saccharopine dehydrogenase (NADP+, L-lysine-forming), occur on a single protein. Group: Enzymes. Synonyms: dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, glutamate-forming); saccharopin dehydrogenase; NAD+ oxidoreductase (L-2-aminoadipic-Δ-semialdehyde and glutamate forming); aminoadipic semialdehyde synthase; 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming). Enzyme Commission Number: EC 1.5.1.9. CAS No. 37256-26-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1536; saccharopine dehydrogenase (NAD+, L-glutamate-forming); EC 1.5.1.9; 37256-26-1; dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, glutamate-forming); saccharopin dehydrogenase; NAD+ oxidoreductase (L-2-aminoadipic-Δ-semialdehyde and glutamate forming); aminoadipic semialdehyde synthase; 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming). Cat No: EXWM-1536.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. This enzyme participates in lysine biosynthesis and lysine degradation. Group: Enzymes. Synonyms: lysine-2-oxoglutarate reductase; dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, lysine forming); ε-N-(L-glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming); N6-(glutar-2-yl)-L-lysine:NAD oxidoreductase (L-lysine-forming); 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming). Enzyme Commission Number: EC 1.5.1.7. CAS No. 9073-96-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1534; saccharopine dehydrogenase (NAD+, L-lysine-forming); EC 1.5.1.7; 9073-96-5; lysine-2-oxoglutarate reductase; dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, lysine forming); ε-N-(L-glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming); N6-(glutar-2-yl)-L-lysine:NAD oxidoreductase (L-lysine-forming); 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming). Cat No: EXWM-1534.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. This enzyme participates in lysine biosynthesis and lysine degradation. Group: Enzymes. Synonyms: saccharopine (nicotinamide adenine dinucleotide phosphate, glutamate-forming) dehydrogenase; aminoadipic semialdehyde-glutamic reductase; aminoadipate semialdehyde-glutamate reductase; aminoadipic semialdehyde-glutamate reductase; ε-N-(L-glutaryl-2)-L-lysine:NAD+(P) oxidoreductase (L-2-aminoadipate-semialdehyde forming); saccharopine reductase; 6-N-(L-1,3-dicar. Enzyme Commission Number: EC 1.5.1.10. CAS No. 9033-55-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1494; saccharopine dehydrogenase (NADP+, L-glutamate-forming); EC 1.5.1.10; 9033-55-0; saccharopine (nicotinamide adenine dinucleotide phosphate, glutamate-forming) dehydrogenase; aminoadipic semialdehyde-glutamic reductase; aminoadipate semialdehyde-glutamate reductase; aminoadipic semialdehyde-glutamate reductase; ε-N-(L-glutaryl-2)-L-lysine:NAD+(P) oxidoreductase (L-2-aminoadipate-semialdehyde forming); saccharopine reductase; 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming). Cat No: EXWM-1494.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. This enzyme participates in lysine biosynthesis and lysine degradation. Group: Enzymes. Synonyms: lysine-2-oxoglutarate reductase; lysine-ketoglutarate reductase; L-lysine-α-ketoglutarate reductase; lysine:α-ketoglutarate:TPNH oxidoreductase (ε-N-[gultaryl-2]-L-lysine forming); saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase; 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming). Enzyme Commission Number: EC 1.5.1.8. CAS No. 9031-19-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1535; saccharopine dehydrogenase (NADP+, L-lysine-forming); EC 1.5.1.8; 9031-19-0; lysine-2-oxoglutarate reductase; lysine-ketoglutarate reductase; L-lysine-α-ketoglutarate reductase; lysine:α-ketoglutarate:TPNH oxidoreductase (ε-N-[gultaryl-2]-L-lysine forming); saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase; 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming). Cat No: EXWM-1535.
S-Acetamidomethyl-3-mercaptopropionic acid
S-Acetamidomethyl-3-mercaptopropionic acid. Group: Biochemicals. Alternative Names: S-Acetamidomethyl-deamino-cysteine. Grades: Highly Purified. CAS No. 52574-08-0. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C6H11NO3S. US Biological Life Sciences.
S-acetylglutathione is a glutathione derivative that has been shown to inhibit the replication of herpes simplex virus 1 (HSV-1) in human foreskin fibroblasts when used at concentrations of 5 and 10 mM. Synonyms: S-acetyl-L-glutathione; Glutathione-S-acetate; 5-[[3-acetylsulfanyl-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-2-amino-5-oxopentanoic acid. Grades: >98%. CAS No. 3054-47-5. Molecular formula: C12H19N3O7S. Mole weight: 349.36.
S-Acetyl-L-Glutathione(Italian & Chinese)
S-Acetyl-L-Glutathione(Italian & Chinese).
CA, FL & NJ
s-Acetylmercaptosuccinic anhydride
S-Acetylmercaptosuccinic anhydride is an amine reactive reagent, containing a sulfhydryl group. The anhydride region opens up, when attacked by an amine nucleophile, forming amine linkage. However, during this ring opening reaction, a free carboxylate group is formed rendering the molecule negatively charged. Activity to proteins and conformation of the molecule us affected by the charge reversal. Uses: This product is suitable for scientific research. Additional or Alternative Names: Ethanethioicacid,S-(tetrahydro-2,5-dioxo-3-furanyl)ester. Product Category: Polymer/MacromoleculeAnhydride Monomers. CAS No. 6953-60-2. Molecular formula: C6H6O4S. Mole weight: 174.18 g/mol. Purity: 0.99. Canonical SMILES: CC(=O)SC1CC(=O)OC1=O. ECNumber: 230-135-2. Product ID: ACM-MO-6953602. Alfa Chemistry ISO 9001:2015 Certified.
S-Acetylmercaptosuccinic anhydride
S-Acetylmercaptosuccinic anhydride. Group: Biochemicals. Grades: Highly Purified. CAS No. 6953-60-2. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
S-Acetylmercaptosuccinic anhydride 99+% (NMR)
S-Acetylmercaptosuccinic anhydride 99+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
S-acetyl-PEG6-alcohol
S-acetyl-PEG6-alcohol. Uses: Designed for use in research and industrial production. Product Category: Other PEG Linkers. CAS No. 1352221-63-6. Molecular formula: C14H28O7S. Mole weight: 340.43. Purity: 95%+. Product ID: ACM1352221636. Alfa Chemistry ISO 9001:2015 Certified.
S-Acetylthioacetic acid
S-Acetylthioacetic acid. Group: Biochemicals. Alternative Names: Acetylthioglycolic acid; Mercapto-acetic acid acetate; S-Acetylmercaptoacetic acid. Grades: Highly Purified. CAS No. 1190-93-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C4H6O3S. US Biological Life Sciences.
Worldwide
s-Acetylthiocholine bromide
s-Acetylthiocholine bromide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ACETYLTHIOCHOLINE BROMIDE;[2-(ACETYLTHIO)ETHYL](TRIMETHYL)AMMONIUM BROMIDE;(2-MERCAPTOETHYL)TRIMETHYLAMMONIUM BROMIDE ACETATE;S-ACETYLTHIOCHOLINE BROMIDE;S-ACETYLTHIOCHOLINE BROMIDE 98%;[2-(Acetylthio)ethyl]trimethylaminium·bromide;2-Acetylthio-N,N,N-tr. Product Category: Heterocyclic Organic Compound. Appearance: WHITE CRYSTALLINE POWDER. CAS No. 25025-59-6. Molecular formula: C7H16NOS.Br. Mole weight: 242.177. Purity: 0.96. IUPACName: 2-acetylsulfanylethyl(trimethyl)azanium bromide. Canonical SMILES: CC(=O)SCC[N+](C)(C)C.[Br-]. Density: g/cm³. ECNumber: 246-570-6. Product ID: ACM25025596. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2-Acetylthioethyltrimethylammonium bromide.
S-Acetylthiocholine iodide
S-Acetylthiocholine iodide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1866-15-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C7H16INOS. US Biological Life Sciences.
Used for linking synthetic peptide antigens to MAP core peptides or carrier proteins for the purpose of raising antibodies. Synonyms: SAMA-OPfp; Pentafluorophenyl-S-acetylthioglycolate. Grades: ≥ 98 % (HPLC). CAS No. 129815-48-1. Molecular formula: C10H5O3F5S. Mole weight: 300.10.
S-Acetylthioglycolic acid pentafluorophenyl ester 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Sacituzumab
Sacituzumab is a humanized monoclonal antibody directed against Trop-2. Sacituzumab has been used in the research of metastatic triple-negative breast cancer. CAS No. 1796566-95-4.
Sacituzumab
Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab is used for the synthesis of antibody-drug conjugates (ADC) drugs. Antibody-drug conjugates with sacituzumab (sacituzumab govitecan) (HY-132254) targeting TROP-2 have been approved for the field of triple-negative breast cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1796566-95-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99045.
Sacituzumab govitecan
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. Sacituzumab govitecan shows anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IMMU-132. CAS No. 1491917-83-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-132254.
Sacituzumab govitecan (solution)
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. Sacituzumab govitecan shows anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IMMU-132 (solution). CAS No. 1491917-83-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132254A.
Sacituzumab tirumotecan
Sacituzumab tirumotecan (SKB264/MK-2870) is a TROP2 ADC. Sacituzumab tirumotecan can be used for the research of triple-negative breast cancer (TNBC) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKB264; MK-2870. CAS No. 2768350-77-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-164789.
Saclofen
Saclofen. Group: Biochemicals. Grades: Purified. CAS No. 125464-42-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Saclofen is a selective antagonist at GABAB receptors. Uses: Gaba antagonists. Synonyms: (RS)-3-Amino-2-(4-chlorophenyl)propylsulfonic acid; 3-amino-2-(4-chlorophenyl)propane-1-sulfonic acid. Grades: ≥99% by HPLC. CAS No. 125464-42-8. Molecular formula: C9H12ClNO3S. Mole weight: 249.72.
Sacubitril
Sacubitril (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC 50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AHU-377. CAS No. 149709-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15407.
Sacubitril
Sacubitril, also known as AHU377 or LCZ696, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume. Synonyms: Sacubitril; AHU 377; AHU377. Grades: >98%. CAS No. 149709-62-6. Molecular formula: C24H29NO5. Mole weight: 411.49.
Sacubitril-(2R, 4R)-Isomer
Sacubitril-(2R, 4R)-isomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Grades: > 95%. Molecular formula: C24H29NO5. Mole weight: 411.5.
Sacubitril-(2S, 4S)-Isomer
Sacubitril-(2S, 4S)-isomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Synonyms: (2S,4S)-Sacubitril; 149709-63-7; 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; 4-[[(2S,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; [1,1'-Biphenyl]-4-pentanoic acid, gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl-, alpha-ethyl ester, (alphaS,gammaS)-; LCZ 696 Impurity C; SCHEMBL18059568; DTXSID901127620; AKOS030528363; AS-80403; HY-78841; CS-0009335; 3-{[(2S,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid; 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoicacid; alpha-Ethyl (alphaS,gammaS)-gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl[1,1'-biphenyl]-4-pentanoate. Grades: > 95%. CAS No. 149709-63-7. Molecular formula: C24H29NO5. Mole weight: 411.5.
Sacubitrilat
Sacubitrilat (Desethyl Sacubitril) is an active neprilysin ( NEP ) inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Desethyl Sacubitril; LBQ-657. CAS No. 149709-44-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17620.
Sacubitril enantiomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Synonyms: 2R,4S-Sacubitril; (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester; 4-[[(2R,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; (2S,4R)-Sacubitril; SCHEMBL22420467; CS-M3545; AKOS030528367; HY-78847; MS-27102; PD100765; L10003; EN300-6474615; A854860; [1,1'-Biphenyl]-4-pentanoic acid, |A-[(3-carboxy-1-oxopropyl)amino]-|A-methyl-, 4-ethyl ester, (|AS,|AR)-; 3-{[(2R,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid; 4-(((2R,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; (alphaS,gammaR)-gamma-[(3-Carboxy-1-oxopropyl)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester. Grades: > 95%. CAS No. 761373-05-1. Molecular formula: C24H29NO5. Mole weight: 411.5.
Sacubitril impurity 11
Sacubitril impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1038924-70-7. Molecular formula: C18H19NO. Mole weight: 265.36. Catalog: APB1038924707.
Sacubitril impurity 12
Sacubitril impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1038924-71-8. Molecular formula: C18H22ClNO2. Mole weight: 319.83. Catalog: APB1038924718.
Sacubitril Impurity 3
An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: (3S,5S)-5-biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one; (3S,5S)-5-[(Biphenyl-4-yl)methyl]-3-methylpyrrolidin-2-one. Grades: > 95%. CAS No. 1038925-00-6. Molecular formula: C18H19NO. Mole weight: 265.36.
Sacubitril impurity 31
Sacubitril impurity 31. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153037-40-2. Molecular formula: C20H25NO3. Mole weight: 327.42. Catalog: APB153037402.
Sacubitril Impurity 4
Sacubitrilat is one of the impurities of Sacubitril which has been found to be an endopeptidase inhibitor and be effective in the treatment of hypertension and heart failure. Synonyms: LBQ-657; LBQ 657; LBQ657; Sacubitrilat; UNII-SPI5PBF81S; LBQ657; CHEMBL417007; (2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid. Grades: 98%. CAS No. 149709-44-4. Molecular formula: C22H25NO5. Mole weight: 383.44.
Sacubitril Impurity 5
An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: (αR,?γR)?-γ-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-α-methyl-[1,?1'-biphenyl]?-4-pentanoic Acid. Grades: > 95%. CAS No. 1012341-56-8. Molecular formula: C23H29NO4. Mole weight: 383.49.
Sacubitril Impurity 6
An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: (αS,?γR)?-γ-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-α-methyl-[1,?1'-biphenyl]?-4-pentanoic Acid. Grades: > 95%. CAS No. 1012341-54-6. Molecular formula: C23H29NO4. Mole weight: 383.49.
Sacubitril Impurity 7
An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: (αS,?γS)?-γ-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-α-methyl-[1,?1'-biphenyl]?-4-pentanoic Acid. Grades: > 95%. CAS No. 1012341-52-4. Molecular formula: C23H29NO4. Mole weight: 383.49.
Sacubitril N-Boc Ester
Sacubitril N-Boc Ester is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: Ethyl (2R, 4S) -5- (4-biphenylyl) -2-methyl-4- ({[ (2-methyl-2-propanyl) oxy]carbonyl}amino) pentanoate; (αR,γS)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-Biphenyl]-4-pentanoic Acid Ethyl Ester; [1,1'-Biphenyl]-4-pentanoic acid, gamma-[[(1,1-dimethylethoxy)carbonyl]amino]-alpha-methyl-, ethyl ester, (alphaR,gammaS)-; Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-4-[(tert-butoxycarbonyl)amino]-2-methylbutanoate. CAS No. 149709-60-4. Molecular formula: C25H33NO4. Mole weight: 411.53.
Sacubitril sodium
Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC 50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AHU-377 sodium. CAS No. 149690-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15407B.