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| Product | Description | |
|---|---|---|
| SJF-8240 | SJF-8240 (PROTAC 7) is a proteolysis targeting chimera (PROTAC) degrader. SJF-8240 induces polyubiquitination of c-Met and inhibits the proliferation of GTL16 cells (IC50=66.7 nM)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230821-68-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123961. |  |
| SK-216 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| SK-216 | SK-216 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor that acts as an anti-metastatic agent for human osteosarcoma and inhibits lung metastasis of human osteosarcoma[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 654080-03-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122714. | |
| SK-575 | SK-575 is a highly potent and specific proteolysis-targeting chimera (PROTAC) degrader of PARP1, with an IC50 of 2.30 nM. SK-575 potently inhibits the growth of cancer cells bearing BRCA1/2 mutations[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2523016-96-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139156. | |
| SK609 hydrochloride | SK609 hydrochloride is a dopamine D3 receptor (D3R) selective agonist with an EC 50 of 1109 nM. SK609 hydrochloride has the potential for parkinson research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092797-77-7. Pack Sizes: 5 mg. Product ID: HY-117059. | |
| SK609 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SKA-121 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SKA 31 | SKA 31. Group: Biochemicals. Grades: Purified. CAS No. 40172-65-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SKA-31 | SKA-31 is a potent potassium channel activator with EC 50s of 260 nM, 1.9 μM, 2.9 μM, and 2.9 μM for KCa3.1 , KCa2.2 , KCa2.1 and KCa2.3 , respectively. SKA-31 potentiates endothelium-derived hyperpolarizing factor response and lowers blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40172-65-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111655. | |
| SKA-31 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Skatole | Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors ( AhR ) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Methylindole; 3-Methyl-1H-indole. CAS No. 83-34-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W007355. | |
| Skeletal Nickel Catalyst slurry in Water | Skeletal Nickel Catalyst slurry in Water. Group: Biochemicals. Alternative Names: Raney Nickel slurry in Water. Grades: Highly Purified. CAS No. 7440-02-0. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences. | Worldwide |
| Skepinone-L | Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CBS3830. CAS No. 1221485-83-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15300. | |
| SKF 38393 hydrobromide | SKF 38393 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 20012-10-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| SKF 38393 hydrochloride | SKF 38393 hydrochloride is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-SKF-38393 hydrochloride; SKF-38393A. CAS No. 62717-42-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12520A. | |
| SKF-525A, Hydrochloride - CAS 62-68-0 | Cell permeable. Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase. Also inhibits hepatic drug metabolism by inhibiting the cytochrome P450 system. Group: Fluorescence/luminescence spectroscopy. | |
| SKF-525A, Hydrochloride (Proadifen, HCl, a-Phenyl-a-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester, HCl) | Cytochrome P-459 inhibitor; blocks glibenclamide-sensitive K+ channels; inhibits neuronal nitric oxide synthetase; stimulates endothelial cell prostacyclin while inhibiting platelet thromboxane synthesis. Group: Biochemicals. Alternative Names: Proadifen, HCl, a-Phenyl-a-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester, HCl. Grades: Highly Purified. Pack Sizes: 2g. US Biological Life Sciences. | Worldwide |
| SKF 81297 | SKF 81297 is a potent and selective dopamine D1 receptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71636-61-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12236A. | |
| SKF 81297 hydrobromide | SKF 81297 hydrobromide is a potent and selective dopamine D1 receptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67287-39-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12236. | |
| SKF 81297 hydrobromide | SKF 81297 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 67287-39-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF 83822 hydrobromide | SKF 83822 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 74115-10-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF 83959 | SKF83959 is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 is a potent allosteric modulator of sigma (σ)-1 receptor. SKF83959 belongs to benzazepine family and has improvements on cognitive dysfunction. SKF83959 can be used for the research of Alzheimer's disease and depression [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80751-85-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-130344. | |
| SKF 83959 hydrobromide | SKF 83959 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 67287-95-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF 83959 hydrobromide | SKF83959 hydrobromide is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 hydrobromide K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 hydrobromide is a potent allosteric modulator of sigma (σ)-1 receptor. SKF83959 hydrobromide belongs to benzazepine family and has improvements on cognitive dysfunction. SKF83959 hydrobromide can be used for the research of Alzheimer's disease and depression [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67287-95-0. Pack Sizes: 5 mg. Product ID: HY-103412. | |
| SKF-83959 hydrobromide | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| SKF86002 | SKF86002 is a p38 MAP kinase inhibitor. SKF86002 inhibits IL-1 beta production by affecting at least two distinct steps in the biosynthesis of this cytokine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKF-86002; SKF 86002; SKF86002. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 72873-74-6. Molecular formula: C16H12FN3S. Mole weight: 297.35. Purity: >98%. IUPACName: 6-(4-Fluorophenyl)-5-(4-pyridyl)-2,3-dihydroimidazo[2,1-b]-thiazole. Canonical SMILES: FC1=CC=C(C2=C(C3=CC=NC=C3)N4C(SCC4)=N2)C=C1. Product ID: ACM72873746. Alfa Chemistry ISO 9001:2015 Certified. |  |
| SKF-86002 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| SKF-86002 - CAS 72873-74-6 | A cell-permeable, reversible, and ATP-competitive cytokine-suppressive anti-inflammatory drug (CSAID). Group: Fluorescence/luminescence spectroscopy. | |
| SKF 86002 dihydrochloride | SKF 86002 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 116339-68-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF 86466 hydrochloride | SKF 86466 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 86129-54-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF-89145 hydrobromide | >98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| SKF89976A | SKF89976A is a potent GABA uptake inhibitor, which is selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). SKF89976A inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). It is able to pass the blood-brain barrier after systemic administration and is active in vivo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKF89976A; SKF 89976A; SKF-89976A. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 85375-15-1. Molecular formula: C22H25NO2. Mole weight: 335.45. Purity: >98%. IUPACName: 1-(4,4-diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid. Canonical SMILES: O=C(C1CN(CC/C=C(C2=CC=CC=C2)/C3=CC=CC=C3)CCC1)O. Product ID: ACM85375151-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| SKF-89976A | >98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| SKF89976A HCl | SKF89976A is a potent GABA uptake inhibitor, which is selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). SKF89976A inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). It is able to pass the blood-brain barrier after systemic administration and is active in vivo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKF89976A HCl; SKF 89976A; SKF-89976A; SKF89976A hydrochloride. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 85375-85-5. Molecular formula: C22H26ClNO2. Mole weight: 371.9. Purity: >98%. IUPACName: 1-(4,4-diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride. Canonical SMILES: O=C(C1CN(CC/C=C(C2=CC=CC=C2)/C3=CC=CC=C3)CCC1)O.[H]Cl. Product ID: ACM85375855-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| SKF89976A hydrochloride | SKF89976A hydrochloride is a selective GABA transporter ( GAT-1 ) inhibitor with IC 50 s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: d,l-SKF89976A hydrochloride. CAS No. 85375-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100228A. | |
| SKF 91488 dihydrochloride | SKF 91488 (Homodimaprit) dihydrochloride is a potent and noncompetitive histamine N-methyltransferase inhibitor with a K i value of 0.9 microM. SKF 91488 dihydrochloride inhibits the methylation of labeled histamine in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Homodimaprit dihydrochloride. CAS No. 68941-21-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100967. | |
| SKF 91488 dihydrochloride | SKF 91488 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 68941-21-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF-96365 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| SKF 96365 hydrochloride | SKF 96365 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 130495-35-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF-96365 hydrochloride | SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca 2+ entry (SOCE) inhibitor. SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1, hKir2.1 and hKv4.3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130495-35-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100001. | |
| SKF-96365 hydrochloride | SKF-96365 hydrochloride is a non-selective TRP Channel blocker. |  |
| SKF 97541 | SKF 97541. Group: Biochemicals. Grades: Purified. CAS No. 127729-35-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKI-178 | SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor (IC50 = 0.1-1.8 μM). SKI-178 induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during prolonged mitosis, mediated by SKI-178 leads to the simultaneous phosphorylation of the prosurvival Bcl-2 family members, Bcl-2 and Bcl-xl, as well as the phosphorylation and subsequent degradation of Mcl-1. SKI-178 is a novel therapeutic agent for the treatment of AML, including multidrug-resistant/recurrent AML subtypes. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKI-178; SKI 178; SKI178. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1259484-97-3. Molecular formula: C21H22N4O4. Mole weight: 394.43. Purity: >98%. IUPACName: N'-(1-(3,4-Dimethoxyphenyl)ethylidene)-3-(4-methoxyphenyl)-1H-pyrazole-5-carbohydrazide. Canonical SMILES: O=C(C1=CC(C2=CC=C(OC)C=C2)=NN1)N/N=C(C3=CC=C(OC)C(OC)=C3)\C. Product ID: ACM1259484973. Alfa Chemistry ISO 9001:2015 Certified. | |
| SKI 5C | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SKI-I | SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK) , with an IC 50 of 1.2 μM for ST-hSK. SKI-I also inhibits hERK2 ( IC 50 =11 μM). SKI-I induces apoptosis in tumor cell lines [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 306301-68-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115735. | |
| SKI II | SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC 50 values of 78 μM and 45 μM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312636-16-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13822. | |
| SKI II | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| SKI II | SKI II. Group: Biochemicals. Grades: Purified. CAS No. 312636-16-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKI-II, Sphingosine Kinase Inhibitor (4- [ [4- (4-Chlorophenyl) -2-thiazolyl] amino] phenol) | Cell-permeable. SKI-II is selective a non-lipid sphingosine kinase (SK) inhibitor. It displays non-ATP-competitive inhibition of human recombinant GST-SK 1 with an IC50 value of 0.5uM, with no inhibition against ERK2, PI3-kinase, or PKCa at concentrations up to 60uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 312636-16-1. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| SKI-I, Sphingosine Kinase Inhibitor (5-naphthalen-2-yl-2H-pyrazole-3-carboxylic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide) | Cell-permeable. SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy. Group: Biochemicals. Grades: Highly Purified. CAS No. 306301-68-8. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Skimmed milk powder (major and trace elements) | certified Reference Material. Group: Food matrix crms. | |
| Skimmianine | Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity [1]. Uses: Scientific research. Group: Natural products. CAS No. 83-95-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2081. | |
| Skimmianine | Skimmianine. Group: Biochemicals. Alternative Names: β-Fagarine; Chloroxylonine; Pentaphylline; 7,8-Dimethoxydictamnine. Grades: Plant Grade. CAS No. 83-95-4. Pack Sizes: 20mg. Molecular Formula: C14H13NO4, Molecular Weight: 259.257. US Biological Life Sciences. | Worldwide |
| Skim Milk | Skim Milk - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Skim Milk Blend | Skim Milk Blend - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Skim Milk Powder with Melamine, Level A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Skim Milk Powder with Melamine, Level C | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Skimmin | Skimmin. Group: Biochemicals. Grades: Plant Grade. CAS No. 93-39-0. Pack Sizes: 20mg. Molecular Formula: C15H16O8, Molecular Weight: 324.28. US Biological Life Sciences. | Worldwide |
| Skim Powder with Melamine, Level E | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| SkinBrite-30 | SkinBrite-30 is a water soluble, diamide salt of azelaic acid that improves the technical characteristics for formulation. Azelaic acid itself has very poor water solubility, however, it is found in many grain proteins and is a beneficial component of the skin. Uses: Skin lightening, Sebum control, Moisturization. Group: Skin Care Active Ingredients. INCI Name: Potassium Azeloyl Diglycinate (PAD. CAS Number: 477773-67-4. Category: Azelaic Acid derivatives. |  United States and all of its trading partners.. |
| SkinBrite-99 | SkinBrite-99 is a highly concentrated form of glycolic acid. Glycolic acid is an exfoliant. It revitalizes skin and reduces the appearance of fine lines and wrinkles by removing the outer layer of dead skin and bringing a new layer of skin to the surface. Uses: Anti-wrinkle, Exfoliation, Skin lightening, Anti-acne,. Group: Skin Care Active Ingredients. INCI Name: Glycolic Acid. CAS Number: 79-14-1. | United States and all of its trading partners.. |
| Skirtboard Rubber | Skirtboard Rubber. Group: Polymers. |  |
| SKI V | SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC 50 of 2 μM for GST-hSK. SKI V potently inhibits PI3K with an IC 50 of 6 μM for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P). SKI V induces apoptosis and has antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24418-86-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12895. | |
| SKL2001 | SKL2001 is an agonist of the Wnt/?-catenin pathway, with anti-cancer activity. SKL2001 stabilizes intracellular ?-catenin via disruption of the Axin/?-catenin interaction[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 909089-13-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-101085. | |
| SKL2001 free base | SKL-2001 is a novel agonist of Wnt/β-catenin signaling pathway. SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex. SKL2001 inhibited proliferation of colon cancer cells cultured in 3D spheroid and induced them accumulation in the G0/G1 phase of the cell cycle with a reduced c-myc level. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKL-2001; SKL 2001; SKL2001; Wnt Agonist II. Product Category: Agonists. Appearance: Solid powder. CAS No. 909089-13-0. Molecular formula: C14H14N4O3. Mole weight: 286.29. Purity: >98%. IUPACName: 5-(Furan-2-yl)-N-(3-imidazol-1-ylpropyl)-1,2-oxazole-3-carboxamide. Canonical SMILES: O=C(C1=NOC(C2=CC=CO2)=C1)NCCCN3C=CN=C3. Product ID: ACM909089130. Alfa Chemistry ISO 9001:2015 Certified. | |
| SKLB1002 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SKLB-197 | SKLB-197 is a potent and highly selective ATR inhibitor. SKLB-197 showed an IC50 value of 0.013 μM against ATR but very weak or no activity against other 402 protein kinases. It displayed potent antitumor activity against ATM-deficent tumors both in vitro and in vivo. In addition, this compound exhibited good pharmacokinetic properties. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKLB-197; SKLB 197; SKLB197. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2713577-16-1. Molecular formula: C25H24N6O. Mole weight: 424.51. Purity: >98%. IUPACName: Quinazoline, 2-(1H-indol-4-yl)-4-[(3R)-3-methyl-4-morpholinyl]-6-(1-methyl-1H-pyrazol-5-yl)-. Canonical SMILES: CN1N=CC=C1C2=CC3=C(N4[C@H](C)COCC4)N=C(C5=CC=CC6=C5C=CN6)N=C3C=C2. Product ID: ACM2713577161. Alfa Chemistry ISO 9001:2015 Certified. | |
| SKLB325 | SKLB325 is a Jumonji domain-containing 6 (JMJD6) inhibitor with a binding affinity (KD) value of 0.755 ?M, and the IC50 value of 0.7797 ?M. SKLB325 exhibits antitumor effects on ovarian cancer in vivo and in vitro. SKLB325 induces apoptosis[1]. SKLB325 exhibits remarkable antitumor efficacy in renal cell carcinoma (RCC) [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66680-03-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139782. | |
| SK-N-SH Transfection Reagent | Transfection Reagent for SKNSH Neuroblastoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 6916. |  Nevada, Texas, USA |
| Skp2 Inhibitor C1 | Skp2 Inhibitor C1 (SKPin C1) is an S-phase kinase-related protein 2 (Skp2) inhibitor with an inhibitory effect on metastatic melanoma cells. Skp2 Inhibitor C1 slows the cell cycle, inhibits cell proliferation, and triggers apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKPin C1. CAS No. 432001-69-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16661. | |
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