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| Product | Description | |
|---|---|---|
| Sirpiglenastat | Sirpiglenastat is a glutaminase inhibitor. Synonyms: sirpiglenastatum; DRP-104; DRP104. Grades: >98%. CAS No. 2079939-05-0. Molecular formula: C22H27N5O5. Mole weight: 441.5. |  |
| SirReal2 | SirReal2 selectively targets SIRT2 and decreases migration as well as invasion in human GC cells. Synonyms: SirReal 2. Grades: 98%. CAS No. 709002-46-0. Molecular formula: C22H20N4OS2. Mole weight: 420.55. | |
| SirReal 2 | SirReal 2. Group: Biochemicals. Grades: Purified. CAS No. 709002-46-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SIRT1/2/3 pan Inhibitor (pan SIRT1/2/3 Inhibitor, 4- (4- (2-Pivalamidoethyl) piperidin-1-yl) thieno[3, 2-d]pyrimidine-6-carboxamide) | A thienopyrimidinyl carboxamide that acts as a highly potent, reversible pan sirtuin (SIRT) inhibitor (IC50 = 15, 10, and 33nM for SIRT1, 2, and 3, respectively). Shown to bind to the SIRT catalytic site and occupy both the nicotinamide C-pocket and acetyl lysine substrate channel. Exhibits high selectivity over a panel of protein kinases, nuclelar receptors, GPCRs, and ion-channels (IC50 > 10uM). Poorly affects hERG and cytochrome P450s (> 50uM). Exhibits desirable stability in microsomal preparations (human CLint = 15.8 uL/min/mg, mouse CLint = 12.7uL/min/mg) and high solubility (297uM), and low LogD (2.73). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. | Worldwide |
| SIRT1 Activator II (3- (Benzenesulfonyl) -1- (4-fluorophenyl) pyrrolo[4, 5-b]quinoxalin-2-amine) | A cell-permeable pyrroloquinoxaline compound that acts as a reversible SIRT1 activator (10uM causes ~2.3-fold fluorescent enhancement in a fluorescent assay using hrSIRT1) and enhances fat mobilization in fully differentiated 3T3L1 fibroblasts. Shown to inhibit LPS-induced TNF-a release in THP-1 cells by ~10-fold more potent than resveratrol. Group: Biochemicals. Grades: Highly Purified. CAS No. 374922-43-7. Pack Sizes: 10mg. Molecular Formula: C??H??FN?O?S, Molecular Weight: 418.4. US Biological Life Sciences. | Worldwide |
| SIRT1-IN-2 | SIRT1-IN-2 (compound 3h) is a potent and selective SIRT1 (silent information regulator 1) inhibitor, with an IC 50 of 1.6 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2470969-89-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146689. |  |
| SIRT1-IN-3 | SIRT1-IN-3 (compound 3j) is a potent and selective SIRT1 inhibitor, with an IC 50 of 4.2 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2470969-91-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146690. | |
| SIRT1-IN-4 | SIRT1-IN-4 (Compound 8c) is a SIRT1 inhibitor, with an IC 50 of 10.04 μM. SIRT1-IN-4 can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 445405-18-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-169934. | |
| SIRT2 Inhibitor (3-(1-azepanylsulfonyl)-N-(3-bromphenyl)benzamide) | Brain-permeable. A potent and selective sirtuin 2 deacetylase (SIRT2) inhibitor. Reduces neuronal cholesterol by inhibiting SIRT2 activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 420831-40-9. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Sirtinol | Sirtinol is a SIRT inhibitor. Sirtinol significantly increased the acetylation of p53, which has been reported to be a target of SIRT1/2. Sirtinol significantly increased the G1 phase of the cell cycle. Synonyms: 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide; 2-{[(2-hydroxy-1-naphthyl)methylene]amino}-N-(1-phenylethyl)benzamide; 2-[(2-hydroxynaphthalen-1-yl)methylideneamino]-N-(1-phenylethyl)benzamide; Sir Two Inhibitor Naphthol; (E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide; 2-(((2-Hydroxynaphthalen-1-yl)methylene)amino)-N-(1-phenylethyl)benzamide; 2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]- N -(1-phenylethyl)benzamide; (E)-2-(((2-HYDROXYNAPHTHALEN-1-YL)METHYLENE)AMINO)-N-(1-PHENYLETHYL)BENZAMIDE; {2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]}-N-(1-phenethyl)benzamide (Sirtinol. Grades: 0.98. CAS No. 410536-97-9. Molecular formula: C26H22N2O2. Mole weight: 394.474. | |
| Sirtinol | Sirtinol is a sirtuin (SIRT) inhibitor, with IC 50 s of 48 μM, 57.7 μM and 131 μM for ySir2, hSIRT2 and hSIRT2, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 410536-97-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13515. | |
| Sirtinol | Sirtinol is a known inhibitor of the NAD+-Dependent Protein Desuccinylase and Demalonylase Sirt5 and exhibits anticancer properties. Group: Biochemicals. Alternative Names: 2-[[ (2-hydroxy-1-naphthalenyl) methylene]amino]-N- (1-phenylethyl) -benzamide; Sir Two Inhibitor Naphthol. Grades: Highly Purified. CAS No. 410536-97-9. Pack Sizes: 10mg, 25mg. US Biological Life Sciences. | Worldwide |
| Sirtinol (SIRT2 Inhibitor Naphthol) | Cell-permeable. A selective sirtuin deacetylase inhibitor with IC50 values of 38, 68 and 131uM for SIRT2, Sir2p and SIRT1 respectively. Sirtinol has no effect on HDAC1 activity. Sirtinol inhibits the growth of cancer cells and suppresses inflammatory signaling in human dermal microvascular endothelial cells. Group: Biochemicals. Alternative Names: 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide. Grades: Highly Purified. CAS No. 410536-97-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Sirtinol (Sir Two Inhibitor Naphthol, 2-N-(1-phenethyl)benzamide) | Specific cell permeable SIRT1 (sirtuin-1) inhibitor. Senescence-like growth arrest inducer. Platelet aggregation inhibitor. Apoptosis inducer. Group: Biochemicals. Alternative Names: Sir Two Inhibitor Naphthol, 2--N-(1-phenethyl)benzamide. Grades: Highly Purified. CAS No. 410536-97-9. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| Sirtuin-1 inhibitor 1 | Sirtuin-1 inhibitor 1 (Compound 8) is an inhibitor of Sirtuin -1 that plays important roles in obesity-induced diabetes and aging-related diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 945114-10-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156781. | |
| Sirtuin-3 Inhibitor, SRT1720 (SIRT3 Inhibitor II, N- (2- (3- (1-Piperazinylmethyl) imidazo[2, 1-b]thiazol-6-yl) phenyl) -2-quinolinecarboxamide) | A cell-permeable quinolinecarboxamide compound that is shown to inhibit the mitochondrial SIRT3 in a substrate AceCS2-competitive (Ki = 0.56uM; Km = 2.44uM), but NAD+-uncompetitive (Ki = 0.34uM; Km = 280uM), manner. Also reported to decrease cellular p53 Lys382 acetylation (Effective conc. = 10uM in U2OS and MEF cultures) and inhibit p300 HAT activity (IC50 = 9uM) in vitro, as well as offer therapeutic benefits in several murine and rodent type 2 diabetes models (100mg/kg/dayl p.o.) in vivo. Whether and how SRT1720 activates SIRT1 activity remains uncertain. Group: Biochemicals. Grades: Highly Purified. CAS No. 925434-55-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Sirukumab | Sirukumab (CNTO-136) is a humanized monoclonal anti- IL6 (Interleukin Related) IgG1κ antibody. Sirukumab binds to IL6 , preventing IL6-mediated signal transduction and activation of transcriptional activators, thereby blocking the downstream biological effects of IL6. Sirukumab can be used in the study of active lupus nephritis and rheumatoid arthritis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CNTO-136. CAS No. 1194585-53-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99316. | |
| SIS3 | SIS3. Group: Biochemicals. Grades: Purified. CAS No. 521984-48-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SIS3 HCl | SIS3 is a potent and specific inhibitor of Smad3 via inhibiting the effects of TGF-β1. SIS3 inhibits TGF-β and activin signaling by suppressing Smad3 phosphorylation with no effect on Smad2, p38 MAPK, ERK or PI 3-kinase signaling. It inhibits TGF-β1-induced myofibroblast differentiation of dermal fibroblasts. Synonyms: (2E)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-propenone hydrochloride. Grades: >98%. CAS No. 521984-48-5. Molecular formula: C28H27N3O3.HCl. Mole weight: 489.99. | |
| Sisomicin | Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Antibiotic 6640; Rickamicin. CAS No. 32385-11-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1222A. | |
| Sisomicin | Antibacterial. Gentamicin-like aminoglycoside antibiotic; has broad spectrum antibiotic activity. Group: Biochemicals. Alternative Names: O-3-Deoxy-4-C-methyl-3-(methylamino)- β-L-arabinopyranosyl-(1-6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1-4)]-2-deoxy- D-Streptamine; Antibiotic 66-40; Antibiotic 6640; Rickamicin; Sch 13475; Siseptin. Grades: Highly Purified. CAS No. 32385-11-8. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Sisomicin | It is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis NRRL 3292. It has a broad-spectrum antibacterial effects against Gram-positive and Gram-negative bacteria including B. subtilis, S. aureus, E. coli, and P. aeruginosa. It has no cross-resistance to kanamycin, but has cross-resistance to gentamycin. 50 mg/kg of Sisomicin has protective effect on mice infected with Rickettsia spinosa. Uses: Protein synthesis inhibitors. Synonyms: D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1?6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1?4)]-2-deoxy-; Antibiotic 6640; SCH 13475; Rickamicin; Sisomycin; Sissomicin; O-3-Deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1?6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1?4)]-2-deoxy-D-streptamine; Antibiotic 66-40; BactoCeaze; Ensamycin; Sch 13475; Siseptin. Grades: ≥98%. CAS No. 32385-11-8. Molecular formula: C19H37N5O7. Mole weight: 447.53. | |
| Sisomicin B | It is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis. It has broad-spectrum antimicrobial activity. Synonyms: Sisomicin B; 6-O-[3-Deoxy-3-(methylamino)-α-D-xylopyranosyl]-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hexa-4-enopyranosyl)-2-deoxy-D-streptamine; Antibiotic 66-40B; 6640B; D-Streptamine, O-3-deoxy-3-(methylamino)-alpha-D-xylopyranosyl-(1-6)-o-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4))-2-deoxy-. CAS No. 53797-16-3. Molecular formula: C18H35N5O7. Mole weight: 433.50. | |
| Sisomicin D | It is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis. It has broad-spectrum antimicrobial activity. Synonyms: 6-O-[3-Deoxy-3-(methylamino)-β-L-arabinopyranosyl]-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hexa-4-enopyranosyl)-2-deoxy-D-streptamine; Antibiotic 66-40D; 66-40D. CAS No. 53759-50-5. Molecular formula: C18H35N5O7. Mole weight: 433.50. | |
| Sisomicin impurity 1 | Sisomicin impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H24N4O4. Mole Weight: 288.35. Catalog: APB11397. |  |
| Sisomicin impurity 2 | Sisomicin impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H35N5O7. Mole Weight: 433.51. Catalog: APB11396. | |
| Sisomicin impurity 3 | Sisomicin impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H35N5O7. Mole Weight: 433.51. Catalog: APB11399. | |
| Sisomicin impurity 4 | Sisomicin impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 53759-50-5. Molecular Formula: C18H35N5O7. Mole Weight: 433.51. Catalog: APB53759505. | |
| Sisomicin impurity 5 | Sisomicin impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C19H35N5O8. Mole Weight: 461.52. Catalog: APB11401. | |
| Sisomicin impurity 6 | Sisomicin impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 53797-16-3. Molecular Formula: C18H35N5O7. Mole Weight: 433.51. Catalog: APB53797163. | |
| Sisomicin impurity 7 | Sisomicin impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H24N4O4. Mole Weight: 288.35. Catalog: APB11400. | |
| Sisomicin impurity 8 | Sisomicin impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H35N5O7. Mole Weight: 433.51. Catalog: APB11402. | |
| Sisomicin sulfate | Sisomicin sulfate. Group: Biochemicals. Grades: Highly Purified. CAS No. 53179-09-2. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: 2C19H37N5O7·5H2SO4. US Biological Life Sciences. | Worldwide |
| Sisomicin sulfate | Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 53179-09-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B1222. | |
| Sisomicin Sulfate | Sisomicin Sulfate is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis NRRL 3292. It has a broad-spectrum antibacterial effects against Gram-positive and Gram-negative bacteria. Uses: Protein synthesis inhibitors. Synonyms: D-Streptamine, 4-O-[(2S,3R)-3-amino-6-(aminomethyl-3,4-dihydro-2H-pyran-2-y1]-2-deoxy-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]-, sulfate (salt); D-Streptamine, 4-O-[3-amino-6-(aminomethyl-3,4-dihydro-2H-pyran-2-y1]-2-deoxy-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]-, (2S-cis)-, sulfate (salt). Grades: ≥95%. CAS No. 53776-71-9. Molecular formula: C19H37N5O7.xH2O4S. Mole weight: 447.52 (free base). | |
| Sisomicin (sulfate) (Standard) | Sisomicin (sulfate) (Standard) is the analytical standard of Sisomicin (sulfate). This product is intended for research and analytical applications. Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 53179-09-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1222R. | |
| s-Isopropyl chlorothioformate,96% | s-Isopropyl chlorothioformate,96%. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-Isopropyl chlorothioformate, 13889-93-5, ACMC-20ajpu, AGN-PC-00LTUK, 674184_ALDRICH, CTK0G9492, Carbonochloridothioic acid, S-(1-methylethyl) ester. Product Category: Heterocyclic Organic Compound. CAS No. 13889-93-5. Molecular formula: C4H7ClOS. Mole weight: 138.62. Purity: 0.96. IUPACName: S-propan-2-yl chloromethanethioate. Canonical SMILES: CC(C)SC(=O)Cl. Density: 1.116 g/mL at 25ºC. Product ID: ACM13889935. Alfa Chemistry ISO 9001:2015 Certified. |  |
| S-Isopropylisothiourea hydrobromide | S-Isopropylisothiourea (IPTU) hydrobromide is a potent and selective inhibitor of Nitric Oxide Synthase (NOS). S-Isopropylisothiourea (IPTU) hydrobromide is used in the research for hemorrhagic shock [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-isopropyl ITU; IPTU. CAS No. 4269-97-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-101304. | |
| S-Isopropylisothiourea hydrobromide | S-Isopropylisothiourea hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 4269-97-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| S-Isopropylisothiourea hydrobromide | S-Isopropylisothiourea hydrobromide is the hydrobromide form of S-Isopropylisothiourea, which is a potent non-selective nitric oxide synthase (NOS) inhibitor. It has selectivity for the inducible form and is selective in vitro but may lack good in vivo efficacy due to poor cellular penetration. Its Ki values are 9.8, 22, and 37 nM using purified human iNOS, eNOS, and nNOS, respectively. It may be useful as a target for various disease models. Synonyms: Carbamimidothioic acid, 1-methylethyl ester, monohydrobromide; 2-Isopropyl-2-thiopsuedourea Hydrobromide; IPITU hydrobromide; S-Isopropylthiuronium bromide; Pseudourea, 2-isopropyl-2-thio-, hydrobromide; Isopropyl carbamimidothioate hydrobromide; S-Isopropyl-ITU hydrobromide; S-Isopropylisothiourea monohydrobromide. Grades: ≥95%. CAS No. 4269-97-0. Molecular formula: C4H11N2SBr. Mole weight: 199.11. | |
| s-Isopropylthiourea hydrobromide | s-Isopropylthiourea hydrobromide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-ISOPROPYLISOTHIOUREA HYDROBROMIDE;S-ISOPROPYL ITU;S-ISOPROPYL-ITU HYDROBROMIDE;S-ISOPROPYLTHIOUREA HYDROBROMIDE;ISOPROPYL CARBAMIMIDOTHIOATE, HYDROBROMIDE;IPTU;5-ISOPROPYLTHIURONIUM BROMIDE;Zinc03806248. Product Category: Heterocyclic Organic Compound. CAS No. 57200-31-4. Molecular formula: C4H11BrN2S. Mole weight: 199.11. Purity: 0.96. IUPACName: propan-2-yl carbamimidothioate. Density: g/cm³. Product ID: ACM57200314. Alfa Chemistry ISO 9001:2015 Certified. | |
| Sisunatovir | Sisunatovir is a highly potent fusion inhibitor with efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses. Sisunatovir exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection. Synonyms: RV-521; RV 521; RV521. Grades: 99.08%. CAS No. 1903763-82-5. Molecular formula: C23H22F4N4O. Mole weight: 446.44. | |
| Sisunatovir | Sisunatovir (RV521), an orally available inhibitor of the RSV protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC 50 s of 1.4 nM and 1.0 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RV521. CAS No. 1903763-82-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123475. | |
| Sisunatovir hydrochloride | Sisunatovir (RV521) hydrochloride, an orally available inhibitor of the RSV fusion (RSV-F) protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC 50 s of 1.4?nM and 1.0?nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RV521 hydrochloride. CAS No. 1903763-83-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123475A. | |
| Sitaclonium chloride ( Cetalkonium Chloride ) | Sitaclonium chloride ( Cetalkonium Chloride ). Uses: For analytical and research use. Group: Impurity standards. CAS No. 122-18-9. Molecular Formula: C25H46ClN. Mole Weight: 396.1. Catalog: APB122189. | |
| Sitafloxacin | Sitafloxacin, a new-generation, broad-spectrum oral fluoroquinolone that is very active against many Gram-positive, Gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was recently approved in Japan for the treatment of respiratory and urinary tract infections. In terms of clinical efficacy, oral sitafloxacin was noninferior to oral levofloxacin in the treatment of community-acquired pneumonia or an infectious exacerbation of chronic respiratory tract disease, noninferior to oral tosufloxacin in the treatment of community-acquired pneumonia, and noninferior to oral levofloxacin in the treatment of complicated urinary tract infections, according to the results of randomized, double-blind, multicentre, noninferiority trials. Noncomparative studies demonstrated the efficacy of oral sitafloxacin in otorhinolaryngological infections, urethritis in men, C. trachomatis-associated cervicitis in women and odontogenic infections. Synonyms: 7-((S)-7-amino-5-azaspiro[24]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; DU 6859; DU-6859; DU6859; DU 6859A; DU-6859A; DU6859A; Sitafloxacin; Sitafloxacin hydrate, Sitafloxacin anhydrous, Trade name: Gracevit. Grades: >98%. CAS No. 127254-12-0. Molecular formula: C19H18ClF2N3O3. Mole weight: 409.81. | |
| Sitafloxacin | Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU6859a. CAS No. 127254-12-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0395. | |
| Sitafloxacin Dechloro Impurity | An impurity of Sitafloxacin. Sitafloxacin is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. Synonyms: 3-Quinolinecarboxylic acid, 7-[(7S)?-7-amino-5-azaspiro[2.4]?hept-5-yl]?-6-fluoro-1-[(1R,?2S)?-2-fluorocyclopropyl]?-1,?4-dihydro-4-oxo-; 7-[(7S)-7-Amino-5-azaspiro[2.4]hept-5-yl]-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid. Grades: > 95%. CAS No. 500569-52-8. Molecular formula: C19H19F2N3O3. Mole weight: 375.37. | |
| Sitafloxacin hydrate | Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic ( antibiotic ) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU6859a hydrate. CAS No. 163253-35-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0395C. | |
| Sitafloxacin Hydrate | Sitafloxacin is active against methicillin-resistant staphylococci, Streptococcus pneumoniae and other streptococci with reduced susceptibility to levofloxacin and other quinolones and enterococci. Synonyms: DU-6859a; DU 6859a; DU6859a. Grades: >98%. CAS No. 163253-35-8. Molecular formula: C19H20ClF2N3O4. Mole weight: 427.8. | |
| Sitafloxacin Impurity 1 | An impurity of Sitafloxacin. Sitafloxacin is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. Grades: > 95%. Molecular formula: C16H16FN3O3. Mole weight: 317.32. | |
| Sitafloxacin Impurity 10 | Sitafloxacin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H13F3N2O. Mole Weight: 338.29. Catalog: APB09790. | |
| Sitafloxacin Impurity 14 | Sitafloxacin Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C19H18F3N3O3. Mole Weight: 393.37. Catalog: APB09792. | |
| Sitafloxacin Impurity 15 | Sitafloxacin Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H13F3N2O3. Mole Weight: 338.29. Catalog: APB09791. | |
| Sitafloxacin Impurity 16 | Sitafloxacin Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 148693-51-0. Molecular Formula: C16H15ClFN3O3. Mole Weight: 351.76. Catalog: APB148693510. | |
| Sitafloxacin Impurity 17 | Sitafloxacin Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C19H19ClF2N4O2. Mole Weight: 408.83. Catalog: APB09793. | |
| Sitafloxacin Impurity 2 | An impurity of Sitafloxacin. Sitafloxacin is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. Grades: > 95%. Molecular formula: C19H19F2N3O4. Mole weight: 391.38. | |
| Sitafloxacin Impurity 20 | Sitafloxacin Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 149404-98-8. Molecular Formula: C3H6FN. Mole Weight: 75.09. Catalog: APB149404988. | |
| Sitafloxacin Impurity 22 | Sitafloxacin Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1638744-20-3. Molecular Formula: C3H7ClFN. Mole Weight: 111.54. Catalog: APB1638744203. | |
| Sitafloxacin Impurity 23 | Sitafloxacin Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 129306-06-5. Molecular Formula: C13H14N2O2. Mole Weight: 230.27. Catalog: APB129306065. | |
| Sitafloxacin Impurity 24 | Sitafloxacin Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 129306-07-6. Molecular Formula: C13H18N2. Mole Weight: 202.3. Catalog: APB129306076. | |
| Sitafloxacin Impurity 25 | Sitafloxacin Impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 144282-35-9. Molecular Formula: C13H18N2. Mole Weight: 202.3. Catalog: APB144282359. | |
| Sitafloxacin Impurity 26 | Sitafloxacin Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1432056-70-6. Molecular Formula: C18H26N2O2. Mole Weight: 302.42. Catalog: APB1432056706. | |
| Sitafloxacin Impurity 27 | Sitafloxacin Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 101513-77-3. Molecular Formula: C7H2ClF3O2. Mole Weight: 210.54. Catalog: APB101513773. | |
| Sitafloxacin Impurity 28 | Sitafloxacin Impurity 28. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C9H4ClF3O3. Mole Weight: 252.57. Catalog: APB09795. | |
| Sitafloxacin Impurity 29 | Sitafloxacin Impurity 29. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C11H9F3O4. Mole Weight: 262.18. Catalog: APB09794. | |
| Sitafloxacin Impurity 30 | Sitafloxacin Impurity 30. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C19H18ClF2N3O3. Mole Weight: 409.82. Catalog: APB09797. | |
| Sitafloxacin Impurity 31 | Sitafloxacin Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C19H18ClF2N3O3. Mole Weight: 409.82. Catalog: APB09796. | |
| Sitafloxacin Impurity 34 | Sitafloxacin Impurity 34. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H8ClF2NO2. Mole Weight: 271.65. Catalog: APB09798. | |
| Sitafloxacin Impurity 35 | Sitafloxacin Impurity 35. Uses: For analytical and research use. Group: Impurity standards. CAS No. 500569-52-8. Molecular Formula: C19H19F2N3O3. Mole Weight: 375.38. Catalog: APB500569528. | |
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