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| Product | Description | |
|---|---|---|
| Sitagliptin Impurity 6 | Sitagliptin Impurity 6 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-N-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)formamide. Grades: > 95%. Molecular formula: C17H15F6N5O2. Mole weight: 435.32. |  |
| Sitagliptin Impurity 60 | Sitagliptin Impurity 60. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1391554-42-9. Molecular Formula: C13H14F3NO3. Mole Weight: 289.25. Catalog: APB1391554429. |  |
| Sitagliptin Impurity 61 | Sitagliptin Impurity 61. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1253055-92-3. Molecular Formula: C11H12F3NO2. Mole Weight: 247.22. Catalog: APB1253055923. | |
| Sitagliptin Impurity 62 | Sitagliptin Impurity 62. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1234321-83-5. Molecular Formula: C13H14F3NO3. Mole Weight: 289.25. Catalog: APB1234321835. | |
| Sitagliptin Impurity 63 | Sitagliptin Impurity 63. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C6H6F3N5O. Mole Weight: 221.14. Catalog: APB09626. | |
| Sitagliptin Impurity 64 | Sitagliptin Impurity 64. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1481965-39-2. Molecular Formula: C7H7F3N4O. Mole Weight: 220.16. Catalog: APB1481965392. | |
| Sitagliptin Impurity 65 | Sitagliptin Impurity 65. Uses: For analytical and research use. Group: Impurity standards. CAS No. 942475-04-9. Molecular Formula: C11H10F2O3. Mole Weight: 228.19. Catalog: APB942475049. | |
| Sitagliptin Impurity 66 | Sitagliptin Impurity 66. Uses: For analytical and research use. Group: Impurity standards. CAS No. 767352-24-9. Molecular Formula: C11H10F2O3. Mole Weight: 228.19. Catalog: APB767352249. | |
| Sitagliptin Impurity 67 | Sitagliptin Impurity 67. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1032506-99-2. Molecular Formula: C11H10F2O3. Mole Weight: 228.19. Catalog: APB1032506992. | |
| Sitagliptin Impurity 68 | Sitagliptin Impurity 68. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C22H26Cl2F6N4O2. Mole Weight: 563.37. Catalog: APB09632. | |
| Sitagliptin Impurity 69 | Sitagliptin Impurity 69. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2248445-00-1. Molecular Formula: C14H14F3NO3. Mole Weight: 310.27. Catalog: APB2248445001. | |
| Sitagliptin Impurity 7 | Sitagliptin Impurity 7 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Grades: > 95%. Molecular formula: C15H17F2N5O. Mole weight: 321.32. | |
| Sitagliptin Impurity 70 | Sitagliptin Impurity 70. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2248445-08-9. Molecular Formula: C14H17F3N2O2. Mole Weight: 302.3. Catalog: APB2248445089. | |
| Sitagliptin Impurity 72 | Sitagliptin Impurity 72. Uses: For analytical and research use. Group: Impurity standards. CAS No. 762240-99-3. Molecular Formula: C4H4ClF3N2O2. Mole Weight: 204.53. Catalog: APB762240993. | |
| Sitagliptin Impurity 73 | Sitagliptin Impurity 73. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H13F6N5O2. Mole Weight: 421.3. Catalog: APB09633. | |
| Sitagliptin Impurity 74 | Sitagliptin Impurity 74. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1256815-03-8. Molecular Formula: C10H7F3O3. Mole Weight: 232.16. Catalog: APB1256815038. | |
| Sitagliptin Impurity 75 | Sitagliptin Impurity 75. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H25F6N5O4. Mole Weight: 525.45. Catalog: APB09634. | |
| Sitagliptin Impurity 77 | Sitagliptin Impurity 77. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H20F3NO2. Mole Weight: 315.34. Catalog: APB09568. | |
| Sitagliptin Impurity 79 | Sitagliptin Impurity 79. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(2-(2,5-difluorophenyl)-1-hydroxyethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione. Molecular Formula: C14H12F2O5. Mole Weight: 298.24. Catalog: APB01746. | |
| Sitagliptin Impurity 8 | Sitagliptin Impurity 8 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Grades: > 95%. Molecular formula: C15H17F2N5O. Mole weight: 321.32. | |
| Sitagliptin Impurity 80 | Sitagliptin Impurity 80. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(2-(2,4-difluorophenyl)-1-hydroxyethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione. Molecular Formula: C14H12F2O5. Mole Weight: 298.24. Catalog: APB01745. | |
| Sitagliptin Impurity 83 | Sitagliptin Impurity 83. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 7-nitroso-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine. CAS No. 2892260-32-9. Molecular Formula: C6H6F3N5O. Mole Weight: 221.14. Catalog: APB2892260329. | |
| Sitagliptin Impurity 8 Dihydrochloride | Sitagliptin Impurity 8 Dihydrochloride is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Molecular formula: C15H19F2N5Cl2O. Mole weight: 394.25. | |
| Sitagliptin Impurity 9 | Sitagliptin Impurity 9 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (Z)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)but-2-enoate. Grades: > 95%. CAS No. 1234321-81-3. Molecular formula: C13H12F3NO3. Mole weight: 287.23. | |
| Sitagliptin Impurity B | Cas No. 898543-70-9. | |
| Sitagliptin impurity D | Cas No. 1379666-94-0. | |
| Sitagliptin Impurity E HCl | Sitagliptin Impurity E HCl is an impurity of Sitagliptin. Sitagliptin is a dipeptidylpeptidase-4 (DPP-4) inhibitor used in the treatment of diabetes mellitus type 2. Grades: > 95%. Molecular formula: C16H15F6N5O.HCl. Mole weight: 443.77. | |
| Sitagliptin impurity F | Sitagliptin Impurity F is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Benzenebutanamide, N,?N'-1,?2-ethanediylbis[β-amino-2,?4,?5-trifluoro-, (βR,?β'R)?-. Grades: > 95%. CAS No. 1608491-98-0. Molecular formula: C22H24F6N4O2. Mole weight: 490.44. | |
| Sitagliptin Impurity G | Cas No. 269396-59-0. | |
| Sitagliptin Impurity H | Sitagliptin Impurity H is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: 3-amino-4-(3,4-difluorophenyl)-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one. CAS No. 1334244-24-4. Molecular formula: C16H16F5N5O. Mole weight: 389.32. | |
| Sitagliptin Impurity H Hydrochloride | Sitagliptin Impurity H Hydrochloride is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: 3-amino-4-(3,4-difluorophenyl)-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one hydrochloride. Grades: > 95%. Molecular formula: C16H16F5N5O.HCl. Mole weight: 425.78. | |
| Sitagliptin Impurity M | Cas No. 218608-98-1. | |
| Sitagliptin Impurity N | Sitagliptin Impurity N is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: 1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one. Molecular formula: C16H14F6N4O. Mole weight: 392.30. | |
| Sitagliptin Impurity N Related Compound | Sitagliptin Impurity N Related Compound is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Molecular formula: C16H10F6N4O. Mole weight: 388.27. | |
| Sitagliptin impurity O | Cas No. 2072867-07-1. | |
| Sitagliptin Impurity O Related Compound | Sitagliptin Impurity O Related Compound is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Molecular formula: C26H21F9N6O2. Mole weight: 620.47. | |
| Sitagliptin Impurity P | Sitagliptin Impurity P is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Molecular formula: C16H17F4N5O. Mole weight: 371.33. | |
| Sitagliptin Impurity P Hydrochloride | Sitagliptin Impurity P Hydrochloride is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Grades: > 95%. Molecular formula: C16H18F4N5ClO. Mole weight: 407.79. | |
| Sitagliptin Methyl-Ester Impurity HCl | Sitagliptin Methyl-Ester Impurity HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1374985-05-3. Molecular Formula: C11H13ClF3NO2. Mole Weight: 283.68. Catalog: APB1374985053. | |
| Sitagliptin N-Phoshate Impurity | Sitagliptin N-Phoshate Impurity is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)phosphoramidic acid. Grades: > 95%. CAS No. 1351498-25-3. Molecular formula: C16H16F6N5O4P. Mole weight: 487.29. | |
| Sitagliptin N-sulfate | Sitagliptin N-sulfate. Group: Biochemicals. Alternative Names: N-[ (1R) -3-[5, 6-Dihydro-3- (trifluoromethyl) -1, 2, 4-triazolo[4, 3-a]pyrazin-7 (8H) -yl]-3-oxo-1-[ (2, 4, 5-trifluorophenyl) methyl]propyl]sulfamic acid. Grades: Highly Purified. CAS No. 940002-57-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C16H15F6N5O4S. US Biological Life Sciences. |  Worldwide |
| Sitagliptin N-Sulfate | Sitagliptin N-Sulfate is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: N-[ (1R) -3-[5, 6-Dihydro-3- (trifluoromethyl) -1, 2, 4-triazolo[4, 3-a]pyrazin-7 (8H) -yl]-3-oxo-1-[ (2, 4, 5-trifluorophenyl) methyl]propyl]sulfamic Acid; (R)-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)sulfamic acid. Grades: > 95%. CAS No. 940002-57-3. Molecular formula: C16H15F6N5O4S. Mole weight: 487.38. | |
| Sitagliptin-N-Sulfate | Sitagliptin-N-Sulfate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 940002-57-3. Molecular Formula: C16H15F6N5O4S. Mole Weight: 487.38. Catalog: APB940002573. | |
| Sitagliptin N-Sulfate Sodium Salt | Sitagliptin N-Sulfate Sodium Salt is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: N-[ (1R) -3-[5, 6-Dihydro-3- (trifluoromethyl) -1, 2, 4-triazolo[4, 3-a]pyrazin-7 (8H) -yl]-3-oxo-1-[ (2, 4, 5-trifluorophenyl) methyl]propyl]sulfamic Acid Sodium Salt; (R)-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)sulfamate, monosodium salt. Grades: >95%. Molecular formula: C16H14F6N5O4NaS. Mole weight: 509.36. | |
| Sitagliptin Oxo impurity | Sitagliptin Oxo impurity is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-7-(3-Amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one; Oxo SLP; Oxo Sitagliptin. Molecular formula: C16H13F6N5O2. Mole weight: 421.30. | |
| sitagliptin phosphate | sitagliptin phosphate. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C7H7F3N4O. Mole Weight: 220.16. Catalog: APB09567. | |
| Sitagliptin phosphate | Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC 50 of 19 nM in Caco-2 cell extracts [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0431 phosphate. CAS No. 654671-78-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13749A. |  |
| Sitagliptin Phosphate | Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Alternative Names: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-phosphate. Grades: Highly Purified. CAS No. 654671-78-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Sitagliptin phosphate monohydrate | Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP4 with an IC 50 of 19 nM in Caco-2 cell extracts [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0431 phosphate monohydrate. CAS No. 654671-77-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13749B. | |
| Sitagliptin Phosphate Monohydrate | Sitagliptin Phosphate Monohydrate is the phosphate salt form of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: MK-0431 phosphate monohydrate; 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate monohydrate. Grades: >98%. CAS No. 654671-77-9. Molecular formula: C16H20F6N5O6P. Mole weight: 523.32. | |
| Sitagliptin Phosphate Monohydrate | Sitagliptin Phosphate Monohydrate. CAS No. 654671-77-9. Product ID: 8-05056. Molecular formula: C16H15F6N5O · H3PO4 · H2O. Mole weight: 523.32. |  |
| Sitagliptin Phosphate Monohydrate | 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-A]pyrazine phosphate monohydrate. CAS No. 654671-77-9. Product ID: 8-04301. Molecular formula: C16H15F6N5O. H3PO4. H2O. Mole weight: 523.33. Purity: 0.99. Properties: white crystalline. | |
| Sitagliptin Phosphate Monohydrate (7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate, MK-0431) | An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release, stimulates the insulin release and lowers blood glucose. Group: Biochemicals. Grades: Highly Purified. CAS No. 654671-77-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Sitagliptin Related Compound 1 | Sitagliptin Related Compound 1 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-3-((tert-Butoxycarbonyl)amino)-4-(3-fluorophenyl)butanoic acid; Boc-(R)-3-amino-4-(3-fluorophenyl)-butyric acid. Grades: >95%. CAS No. 331763-66-7. Molecular formula: C15H20FNO4. Mole weight: 297.32. | |
| Sitagliptin Triazecine Analog | Sitagliptin Triazecine Analog is an impurity of Sitagliptin. Sitagliptin is a dipeptidylpeptidase-4 (DPP-4) inhibitor used in the treatment of diabetes mellitus type 2. Synonyms: 10-(2,4,5-Trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione. Grades: > 95%. Molecular formula: C16H13F6N5O2. Mole weight: 421.30. | |
| Sitamaquine tosylate | Sitamaquine tosylate is a dose-dependent and orally bioactive inhibitor of complex II (succinate dehydrogenase or SDH) of the respiratory chain in digitonin-permeabilized promastigotes. Sitamaquine has the potential for the treatment of life-threatening visceral leishmaniasis (VL) caused by Leishmania donovani (EC50 value 19.8 μM for L. donovani promastigotes in vitro). Synonyms: WR6026 tosylate; WR-6026 tosylate; WR 6026 tosylate. Grades: 99%. CAS No. 1019640-33-5. Molecular formula: C21H33N3O.C7H8O3S. Mole weight: 515.71. | |
| Sitaxentan sodium | Sitaxentan sodium inhibits ET-1-induced stimulation of phosphoinositide turnover with a Ki of 0.69 nM and a pA2 of 8.0. Synonyms: TBC-11251; TBC 11251; TBC11251. Grades: >98%. CAS No. 210421-74-2. Molecular formula: C18H14ClN2O6S2.Na. Mole weight: 476.89. | |
| Sitaxsentan | Sitaxsentan, also called as IPI 1040 or TBC 11251, is a potent orally bioactive ET receptor antagonist that has a long duration of action (t1/2, 5-7 hours) and is approximately 6,500-fold more selective as an antagonist for ETA compared with ETB receptors. Synonyms: N-(4-chloro-3-methyl-1,2-oxazol-5-yl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]thiophene-3-sulfonamide Sitaxentan Sitaxsentan Thelin 184036-34-8 UNII-J9QH779MEM CHEMBL282724 3-Thiophenesulfonamide, N-(4-chloro-3-methyl-5-isoxazolyl)-2-((6-methyl-1,3-ben. Grades: 95%. CAS No. 184036-34-8. Molecular formula: C18H15ClN2O6S2. Mole weight: 454.90. | |
| Sitaxsentan sodium | Sitaxsentan sodium (IPI 1040 sodium; TBC11251 sodium) is an orally active, highly selective antagonist of endothelin A receptors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IPI 1040 sodium; TBC11251 sodium. CAS No. 210421-74-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-11103. | |
| Sitaxsentan sodium | Sitaxsentan sodium. Group: Biochemicals. Alternative Names: N-(4-Chloro-3-methyl-5-isoxazolyl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]-3-thiophenesulfonamide. Grades: Highly Purified. CAS No. 210421-74-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H14ClN2NaO6S2. US Biological Life Sciences. | Worldwide |
| site-1 protease | Cleaves sterol regulatory element-binding proteins (SREBPs) and thereby initiates a process by which the active fragments of the SREBPs translocate to the nucleus and activate genes controlling the synthesis and uptake of cholesterol and unsaturated fatty acids into the bloodstream. The enzyme also processes pro-brain-derived neurotrophic factor and undergoes autocatalytic activation in the endoplasmic reticulum through sequential cleavages. The enzyme can also process the unfolded protein response stress factor ATF6 at an Arg-His-Lys-Lys? site, and the envelope glycoprotein of the highly infectious Lassa virus and Crimean Congo hemorrhagic fever virus at Arg-Arg-Lys-Lys?. Belongs in... No. 167140-48-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4107; site-1 protease; EC 3.4.21.112; 167140-48-9; mammalian subtilisin/kexin isozyme 1; membrane-bound transcription factor site-1 protease; proprotein convertase SKI-1; proprotein convertase SKI-1/S1PPS1; S1P endopeptidase; S1P protease; site-1 peptidase; site-1 protease; SKI-1; SREBP proteinase; SREBP S1 protease; SREBP-1 proteinase; SREBP-2 proteinase; sterol regulatory element-binding protein proteinase; sterol regulatory element-binding protein site 1 protease; sterol-regulated luminal protease; subtilase SKI-1; subtilase SKI-1/S |  |
| site-specific DNA-methyltransferase (adenine-specific) | This is a large group of enzymes, most of which form so-called 'restriction-modification systems' with nucleases that possess similar site specificity [the nucleases are listed as either EC 3.1.21.3 (type 1 site-specific deoxyribonuclease), EC 3.1.21.4 (type II site-specific deoxyribonuclease) or EC 3.1.21.5 (type III site-specific deoxyribonuclease)]. A complete listing of all of these enzymes has been produced by R.J. Roberts and is available on-line at http://rebase. neb. com/rebase/rebase. html. Group: Enzymes. Synonyms: modification methylase; restriction-modification system. Enzyme Commission Number: EC 2.1.1.72. CAS No. 69553-52-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1974; site-specific DNA-methyltransferase (adenine-specific); EC 2.1.1.72; 69553-52-2; modification methylase; restriction-modification system. Cat No: EXWM-1974. | |
| site-specific DNA-methyltransferase (cytosine-N4-specific) | This is a large group of enzymes, most of which, with enzymes of similar site specificity listed as EC 3.1.21.3 (type 1 site-specific deoxyribonuclease), EC 3.1.21.4 (type II site-specific deoxyribonuclease) or EC 3.1.21.5 (type III site-specific deoxyribonuclease), form so-called 'restriction-modification systems'. A complete listing of all of these enzymes has been produced by R.J. Roberts and is available on-line at http://rebase. neb. com/rebase/rebase. html. Group: Enzymes. Synonyms: modification methylase; restriction-modification system; DNA[cytosine-N4]methyltransferase; m4C-forming MTase; S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase. Enzyme Commission Number: EC 2.1.1.113. CAS No. 169592-50-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1712; site-specific DNA-methyltransferase (cytosine-N4-specific); EC 2.1.1.113; 169592-50-1; modification methylase; restriction-modification system; DNA[cytosine-N4]methyltransferase; m4C-forming MTase; S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase. Cat No: EXWM-1712. | |
| Sitoindoside I | Sitoindoside I. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-naphthalen-2-ylamino-1H-pyrimidine-2,4-dione. Appearance: Powder. CAS No. 18749-71-8. Molecular formula: C51H90O7. Mole weight: 815.3. Purity: 0.98. IUPACName: [(2R,3S,4S,5R,6R)-6-[[(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-3,4,5-trihydroxyoxan-2-yl]methyl hexadecanoate. Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OCC1C(C(C(C(O1)OC2CCC3(C4CCC5(C(C4CC=C3C2)CCC5C(C)CCC(CC)C(C)C)C)C)O)O)O. Product ID: ACM18749718. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Sitolactone | Sitolactone. Uses: Designed for use in research and industrial production. Product Category: Steroidal Compounds. CAS No. 126784-20-1. Molecular formula: C13H18O3. Mole weight: 222.28. Purity: 95%+. Product ID: ACM126784201. Alfa Chemistry ISO 9001:2015 Certified. | |
| Sitosterol | Sitosterol Inhibitor. Uses: Scientific use. Product Category: T2966. CAS No. 83-46-5. |  |
| Sitosterol, β- | Sitosterol, β-. Group: Biochemicals. CAS No. 83-46-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Sitosterol-d7 | Sitosterol-d7. Group: Others. Purity: >99%. Mole weight: 421.75. Stability: 6 Months. Storage: -20°C. Avanti Polar Lipids; lipid products; bioactive lipids; fluorescent lipids; singnal transduction; cell pathways; Sitosterol-d7; (24-Ethyl)-heptadeuteriostigmast-5-en-3ss-ol. Cat No: FLBZ-078. | |
| Sitravatinib | Sitravatinib, a new inhibitor of tyrosine kinase, has been studied to have effective in inhibiting tyrosine kinases receptors involved in driving sarcoma cell growth. It is still under a phase II trial for Non small cell lung cancer. IC50: 3980 nmol/L. Uses: Sitravatinib has been studied to have effective in inhibiting tyrosine kinases receptors involved in driving sarcoma cell growth. it is still under a phase ii trial for non small cell lung cancer. Synonyms: MGCD516; MGCD-516; MGCD 516; MG516; MG 516; MG-516; Sitravatinib. Grades: 98%. CAS No. 1123837-84-2. Molecular formula: C33H29F2N5O4S. Mole weight: 629.68. | |
| Sitravatinib | Sitravatinib (MGCD516) is an orally bioavailable receptor tyrosine kinase (RTK) inhibitor with IC 50 s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively [1]. Sitravatinib shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGCD516; MG-516. CAS No. 1123837-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-16961. | |
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