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| Product | Description | |
|---|---|---|
| S-Methoprene | S-Methoprene is an insect juvenile hormone analog and effective insecticide that blocks the transition from pupa to adult. S-Methoprene is also a CB(1) receptor ligand and inhibits the binding of the CB1 receptor antagonist [ 3 H]CP-55940 to the CB1 receptor ( IC 50 : 19.31 μM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Methoprene; (7S)-Methoprene. CAS No. 65733-16-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1161A. |  |
| S-(+)-Methoprene | S-(+)-Methoprene. Group: Biochemicals. Grades: Highly Purified. CAS No. 65733-16-6. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C19H34O3. US Biological Life Sciences. |  Worldwide |
| S-(+)-Methoprene | S-(+)-Methoprene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Isopropyl (2E,4E,7S)-11-Methoxy-3,7,11-Trimethyldodeca-2,4-Dienoate. Product Category: Heterocyclic Organic Compound. CAS No. 65733-16-6. Molecular formula: C19H34O3. Mole weight: 310.47. Purity: 0.95. Canonical SMILES: C[C@@H](CCCC(C)(C)OC)C/C=C/C(=C/C(=O)OC(C)C)/C. Product ID: ACM65733166. Alfa Chemistry ISO 9001:2015 Certified. |  |
| S-Methyl-3-thioacetaminophen | S-Methyl-3-thioacetaminophen. Group: Biochemicals. Alternative Names: N-[4-Hydroxy-3-(methylthio)phenyl]-acetamide; 3- (Methylthio) acetaminophen; 3- (Methylthio) paracetamol. Grades: Highly Purified. CAS No. 37398-23-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C9H11NO2S. US Biological Life Sciences. | Worldwide |
| s-Methyl 4,4,4-trifluoro-3-oxothio-butyr ate,98 | s-Methyl 4,4,4-trifluoro-3-oxothio-butyr ate,98. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-METHYL 4,4,4-TRIFLUORO-3-OXOTHIO-BUTYR ATE, 98;S-methyl 4,4,4-trifluoro-3-oxothio-butyrate;S-Methyl 3-oxo-4,4,4-trifluorothiobutyrate, S-Methyl 4,4,4-trifluoroacetoacetthioate. Product Category: Heterocyclic Organic Compound. CAS No. 118528-85-1. Molecular formula: C5H5F3O2S. Mole weight: 186.1522096. Density: 1.352 g/mL at 25 °C(lit.). Product ID: ACM118528851. Alfa Chemistry ISO 9001:2015 Certified. Categories: S-methyl 4,4,4-trifluoro-3-oxobutanethioate. | |
| s-Methyl 4-methylbenzenethiosulfonate | s-Methyl 4-methylbenzenethiosulfonate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-METHYL 4-METHYLBENZENETHIOSULFONATE;4-methyl-benzenesulfonothioicacis-methylester;thio-p-toluenesulfonicacis-methylester;S-methyl toluene-p-thiosulphonate;4-Methylbenzene-1-thiosulfonic acid S-methyl ester;4-Methylbenzenesulfonothioic acid S-methyl est. Product Category: Heterocyclic Organic Compound. CAS No. 4973-66-4. Molecular formula: C8H10O2S2. Mole weight: 202.29. Product ID: ACM4973664. Alfa Chemistry ISO 9001:2015 Certified. | |
| S-methyl-5'-thioadenosine deaminase | The enzyme from Thermotoga maritima also functions as S-adenosylhomocysteine deaminase (EC 3.5.4.28) and has some activity against adenosine. Adenosine 5'-phosphate and S-adenosyl-L-methionine (SAM) are not substrates. Group: Enzymes. Synonyms: MTA deaminase; 5-methylthioadenosine deaminase. Enzyme Commission Number: EC 3.5.4.31. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4559; S-methyl-5'-thioadenosine deaminase; EC 3.5.4.31; MTA deaminase; 5-methylthioadenosine deaminase. Cat No: EXWM-4559. |  |
| S-methyl-5'-thioadenosine phosphorylase | Also acts on 5'-deoxyadenosine and other analogues having 5'-deoxy groups. Group: Enzymes. Synonyms: 5'-deoxy-5'-methylthioadenosine phosphorylase; MTA phosphorylase; MeSAdo phosphorylase; MeSAdo/Ado phosphorylase; methylthioadenosine phosphorylase; methylthioadenosine nucleoside phosphorylase; 5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase; S-methyl-5-thioadenosine phosphorylase; S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-α-D-ribosyl-transferase. Enzyme Commission Number: EC 2.4.2.28. CAS No. 61970-06-7. MTAP. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2655; S-methyl-5'-thioadenosine phosphorylase; EC 2.4.2.28; 61970-06-7; 5'-deoxy-5'-methylthioadenosine phosphorylase; MTA phosphorylase; MeSAdo phosphorylase; MeSAdo/Ado phosphorylase; methylthioadenosine phosphorylase; methylthioadenosine nucleoside phosphorylase; 5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase; S-methyl-5-thioadenosine phosphorylase; S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-α-D-ribosyl-transferase. Cat No: EXWM-2655. | |
| S-methyl-5'-thioadenosine phosphorylase from Human, Recombinant | MTAP expression is crucial for the catabolism of methylthioadenosine, which is a by-product of polyamine biosynthesis in the methionine salvage pathway. Protein expression is decreased by homozygous deletion and promoter hypermethylation. N-terminal gst-tagged 57 kda protein containing amino acids 2-end. Applications: S-methyl-5?-thioadenosine phosphorylase human (mtap) is an enzyme used in cancer research that is deficient in many types of cancer. decreased mtap expression may be used as a potential indicator of disease progression of gastrointestinal stromal tumors. mtap may be a used to develop potential therapeutic strategies for hepat ocellular carcinoma ...CAS No. 61970-06-7. MTAP. Mole weight: 57 kDa. Storage: -70°C. Form: Supplied as a solution in 25 mM Tris-HCl, pH 8.0,100 mM NaCl, 0.05% Tween-20, 10% glycerol,and 3 mM DTT. Source: E. coli. Species: Human. S-methyl-5'-thioadenosine phosphorylase; EC 2.4.2.28; 5'-deoxy-5'-methylthioadenosine phosphorylase; MTA phosphorylase; MeSAdo phosphorylase; MeSAdo/Ado phosphorylase; methylthioadenosine phosphorylase; methylthioadenosine nucleoside phosphorylase; 5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase; S-methyl-5-thioadenosine phosphorylase; S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-α-D-ribosyl-transferase; MTAP. Cat No: NATE-0462. | |
| S-methyl-5'-thioinosine phosphorylase | No activity with S-methyl-5'-thioadenosine. The catabolism of of 5'-methylthioadenosine in Pseudomonas aeruginosa involves deamination to S-methyl-5'-thioinosine (EC 3.5.4.31, S-methyl-5'-thioadenosine deaminase) and phosphorolysis to hypoxanthine. Group: Enzymes. Synonyms: MTIP; MTI phosphorylase; methylthioinosine phosphorylase. Enzyme Commission Number: EC 2.4.2.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2673; S-methyl-5'-thioinosine phosphorylase; EC 2.4.2.44; MTIP; MTI phosphorylase; methylthioinosine phosphorylase. Cat No: EXWM-2673. | |
| S-methyl-5-thioribose-1-phosphate isomerase | This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. This enzyme participates in methionine metabolism. Group: Enzymes. Synonyms: methylthioribose 1-phosphate isomerase; 1-PMTR isomerase; 5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase; S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase; S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase; 1-phospho-5'-S-methylthioribose isomerase; S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase. Enzyme Commission Number: EC 5.3.1.23. CAS No. 91608-95-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5462; S-methyl-5-thioribose-1-phosphate isomerase; EC 5.3.1.23; 91608-95-6; methylthioribose 1-phosphate isomerase; 1-PMTR isomerase; 5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase; S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase; S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase; 1-phospho-5'-S-methylthioribose isomerase; S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase. Cat No: EXWM-5462. | |
| S-methyl-5-thioribose kinase | CTP also acts, but more slowly. Group: Enzymes. Synonyms: 5-methylthioribose kinase (phosphorylating); methylthioribose kinase; 5-methylthioribose kinase; ATP:S5-methyl-5-thio-D-ribose 1-phosphotransferase. Enzyme Commission Number: EC 2.7.1.100. CAS No. 68247-56-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2947; S-methyl-5-thioribose kinase; EC 2.7.1.100; 68247-56-3; 5-methylthioribose kinase (phosphorylating); methylthioribose kinase; 5-methylthioribose kinase; ATP:S5-methyl-5-thio-D-ribose 1-phosphotransferase. Cat No: EXWM-2947. | |
| S-METHYL-D3-THIOACETAMINOPHEN | S-METHYL-D3-THIOACETAMINOPHEN. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-METHYL-D3-THIOACETAMINOPHEN. Product Category: Heterocyclic Organic Compound. Appearance: Off-White Solid. CAS No. 1215669-56-9. Molecular formula: C9H8D3NOS. Mole weight: 184.2732253. Product ID: ACM1215669569. Alfa Chemistry ISO 9001:2015 Certified. | |
| S-Methyl-D/L-cysteine sulfoxide | S-Methyl-D/L-cysteine sulfoxide. Synonyms: (Methylsulfinyl)alanine; S-Methyl-D/L-Cysteine-S-oxide; S-Methylcysteine S-oxide; D/L-Alanine, 3-(methylsulfinyl)-; S-Methyl-DL-cysteine sulfoxide. Grade: ≥90%. Molecular formula: C4H9NO3S. Mole weight: 151.19. |  |
| S-methyl DM1 | S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds tubulin with a Kd of 0.93 μM and inhibits microtubule polymerization. S-methyl DM1 can effectively inhibit microtubule dynamic instability and has anticancer effects. Synonyms: N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine; [(1S,2R,3S,5S,6S,16Z,18Z,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl(3-methylsulfanylpropanoyl)amino]propanoate. CAS No. 912569-84-7. Molecular formula: C36H50ClN3O10S. Mole weight: 752.31. | |
| S-Methylglutathione | S-Methylglutathione is an S-substitued glutathione and a stronger nucleophile than GSH [1]. S-Methylglutathione has inhibitory effect on glyoxalase 1 [2]. Uses: Scientific research. Group: Peptides. CAS No. 2922-56-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-W009177. | |
| S-Methylglutathione | S-Methylglutathione. Group: Biochemicals. Grades: Highly Purified. CAS No. 2922-56-7. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C11H19N3O6S. US Biological Life Sciences. | Worldwide |
| S-Methylisothiourea sulfate | S-Methylisothiourea sulfate is a potent, selective and competitive inhibitor of inducible nitric oxide synthase (iNOS). S-Methylisothiourea sulfate exerts beneficial effects in rodent models of septic shock [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 867-44-7. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-79457. | |
| S-Methylisothiouronium sulfate | S-Methylisothiouronium sulfate. Group: Biochemicals. Alternative Names: 2-Methyl-2-thiopseudourea sulfate. Grades: Highly Purified. CAS No. 867-44-7. Pack Sizes: 500g, 1Kg, 2Kg, 5kg, 10kg. Molecular Formula: C4H12N4S2·H2SO4. US Biological Life Sciences. | Worldwide |
| S-Methyl-L-cysteine | S-Methyl-L-cysteine is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities. Uses: Scientific research. Group: Natural products. Alternative Names: L-S-Methylcysteine. CAS No. 1187-84-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-B2188. | |
| S-Methyl-L-cysteine | S-Methyl-L-cysteine. Uses: Peptide synthesis. Additional or Alternative Names: (R)-2-Amino-3-(methylmercapto)propionic acid, SMLC. Product Category: Amino Acids. CAS No. 1187-84-4. Molecular formula: CH3SCH2CH(NH2)CO2H. Mole weight: 135.18. Canonical SMILES: CSC[C@H](N)C(O)=O. ECNumber: 214-701-6. Product ID: ACM1187844. Alfa Chemistry ISO 9001:2015 Certified. Categories: S-Methylcysteine. | |
| S-Methyl-L-cysteine | S-Methyl-L-cysteine, a theurapeutic for neurodegenerative diseases, is a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities. Synonyms: S-Methyl-L-cysteine; NSC 15387; NSC15387; NSC-15387; (2R)-2-amino-3-methylsulfanylpropanoic acid; S-11C-methyl-L-cysteine; S-methylcysteine; S-methylcysteine, (DL-Cys)-isomer; S-methylcysteine, (L-Cys)-isomer; S-methylcysteine, hydrochloride, (L-Cys)-isomer. Grade: 98%. CAS No. 1187-84-4. Molecular formula: C4H9NO2S. Mole weight: 135.18. | |
| S-Methyl-L-cysteine | S-Methyl-L-cysteine. CAS No: 1187-84-4 |  Sarchem Laboratories New Jersey NJ |
| S-Methyl-L-cysteine-d3 | S-Methyl-L-cysteine-d3. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| S-Methyl-L-thiocitrulline acetate | S-Methyl-L-thiocitrulline is a potent nitric oxide synthase (NOS) inhibitor with selectivity for neuronal isoform versus eNOS and iNOS (Ki = 1.2, 11, and 40 nM for nNOS, eNOS, and iNOS, respectively). Synonyms: H-ThioCit(S-Me)-OH AcOH; L-Ornithine, N5-[imino(methylthio)methyl]-, acetate (1:1); L-Ornithine, N5-[imino(methylthio)methyl]-, monoacetate; (S)-2-Amino-5-((imino(methylthio)methyl)amino)pentanoic acid acetate. Grade: ≥95%. CAS No. 174063-92-4. Molecular formula: C9H19N3O4S. Mole weight: 265.33. | |
| S-Methyl-L-thiocitrulline acetate salt | ?98% (TLC). Group: Fluorescence/luminescence spectroscopy. |  |
| S-Methyl-L-thiocitrulline dihydrochloride | S-Methyl-L-thiocitrulline is a new potent nitric oxide synthase inhibitor for treatment of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 156719-39-0. Pack Sizes: 10mg, 25mg, 100mg, 250mg. Molecular Formula: C7H15N3O2S HCl. US Biological Life Sciences. | Worldwide |
| S-Methyl-L-thiocitrulline, Dihydrochloride - CAS 209589-59-3 | A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC?? = 300 nM) compared to the endothelial enzyme (IC?? = 5.4 μM). Group: Fluorescence/luminescence spectroscopy. | |
| S-Methyl methanethiosulfonate | analytical standard. Group: Flavor and fragrance standards. | |
| s-Methyl-N,N-diethyldithiocarbamate sulfoxide | s-Methyl-N,N-diethyldithiocarbamate sulfoxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N,N-Diethyl-1-(methylsulfinyl)methanethioamide. Product Category: Heterocyclic Organic Compound. CAS No. 145195-14-8. Molecular formula: C6H13NOS2. Mole weight: 179.3. Product ID: ACM145195148. Alfa Chemistry ISO 9001:2015 Certified. | |
| S-Methyl-N,N-diethyldithiocarbamate sulfoxide | S-Methyl-N,N-diethyldithiocarbamate sulfoxide. Group: Biochemicals. Alternative Names: N, N-Diethyl-1- (methylsulfinyl) methanethioamide. Grades: Highly Purified. CAS No. 145195-14-8. Pack Sizes: 50mg. Molecular Formula: C6H13NOS2. US Biological Life Sciences. | Worldwide |
| S-Methyl-N,N-diethylthiocarbamate | S-Methyl-N,N-diethylthiocarbamate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| S-Methyl-N,N-diethylthiocarbamate Sulfone | A dioxygenated metabolite of Disulfiram (Antabuse) capable of in vitro inactivation of liver mitochondrial aldehyde dehydrogenase (EC 1.2.1.3, ALDH) with higher reactivity than the monooxygenated sulfoxide. Group: Biochemicals. Alternative Names: N, N-Diethyl-1- (methylsulfonyl) formamide. Grades: Highly Purified. CAS No. 155514-79-7. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences. | Worldwide |
| S-Methyl-N,N-diethylthiocarbamate Sulfoxide | An oxygenated metabolite of Disulfiram (Antabuse) that is capable of in vitro inactivation of liver mitochondrial aldehyde dehydrogenase (EC 1.2.1.3, ALDH). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| S-Methyl-thioacetaminophen-[d3] | S-Methyl-thioacetaminophen-[d3]. Uses: A labelled metabolite of acetaminophen. Synonyms: S-Methyl-d3-thioacetaminophen. Grade: 95% atom D. CAS No. 1215669-56-9. Molecular formula: C9H8D3NO2S. Mole weight: 200.27. | |
| s-Methyl thiohexanoate | s-Methyl thiohexanoate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-Methyl hexanethioate;S-(METHYLTHIO)HEXANOATE;METHYL THIOHEXANOATE;METHANETHIOL CAPROATE;FEMA 3862;Hexanethioic acid S-methyl ester. Product Category: Heterocyclic Organic Compound. CAS No. 2432-77-1. Molecular formula: C7H14OS. Mole weight: 146.25. Product ID: ACM2432771. Alfa Chemistry ISO 9001:2015 Certified. | |
| S-Methyl Tiopronin | A metabolite of Tiopronin. Group: Biochemicals. Alternative Names: N-[2-(Methylthio)-1-oxopropyl]glycine. Grades: Highly Purified. CAS No. 87254-91-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| S-Metolachlor Metabolite CGA 357704 | analytical standard. Group: Pesticides & metabolites standards. | |
| S-Metolachlor Metabolite CGA 368208 | analytical standard. Group: Pesticides & metabolites standards. | |
| S-Metolachlor Metabolite CGA 37735 | analytical standard. Group: Pesticides & metabolites standards. | |
| s-Metolachlor metabolite cga 50720 | s-Metolachlor metabolite cga 50720. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S-Metolachlor Metabolite CGA 50720, 152019-74-4, CTK8E7572, AKOS009481030, N-(2-Ethyl-6-methylphenyl)-oxalamic acid, [(2-Ethyl-6-methylphenyl)amino]oxo-acetic acid. Product Category: Heterocyclic Organic Compound. CAS No. 152019-74-4. Molecular formula: C11H13NO3. Mole weight: 207.23. Purity: 0.96. IUPACName: 2-(2-ethyl-6-methylanilino)-2-oxoacetic acid. Canonical SMILES: CCC1=CC=CC(=C1NC(=O)C(=O)O)C. Product ID: ACM152019744. Alfa Chemistry ISO 9001:2015 Certified. | |
| S-Metolachlor Metabolite CGA 50720 | analytical standard. Group: Pesticides & metabolites standards. | |
| S-(+)-Mexiletine hydrochloride | S-(+)-Mexiletine hydrochloride. Group: Biochemicals. Alternative Names: (2S)-1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride; (+)-(S)-Mexiletine hydrochloride; (+)-Mexiletine hydrochloride. Grades: Highly Purified. CAS No. 81771-85-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C11H18ClNO. US Biological Life Sciences. | Worldwide |
| SMF | SMF. Group: Polymers. |  |
| SMI481 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SMI-4a | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SMI-4a | Selective inhibitor of Pim-1 and Pim-2 protein kinases. Inducer of G1 phase cell cycle arrest. Inducer of p27Kip1. Inducer of apoptosis through the mitochondrial pathway. Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway. Downregulates c-myc. Inhibitor of PRAS40 phosphorylation and mTOR activity. Potential anti-cancer compound. Blocks prostate cancer growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 327033-36-3. Pack Sizes: 5mg. Molecular Formula: C11H6F3NO2S, Method for Determining. US Biological Life Sciences. | Worldwide |
| SMI-4a | SMI-4a (TCS-PIM-1-4a) is a poten, selective, cell-permeable and ATP-competitive Pim-1 inhibitor with an IC50 of 24 ?M and a Ki of 0.6 ?M. SMI-4a also inhibits Pim-2 (IC50 of 100 ?M), and does not significantly inhibit the other serine/threonine- or tyrosine-kinases. SMI-4a has anticancer activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TCS-PIM-1-4a. CAS No. 438190-29-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16576A. | |
| SMI-4a (5E/Z) -[[3- (Trifluoromethyl) phenyl]methylene]-2, 4-thiazolidinedione) | A selective, ATP-competitive inhibitor Pim-1 (IC50=21nm) and Pim-2 (IC50=100nm) protein kinases. Blocks mTORC1 activity via activation of AMPK. SMI-4a has been found to inhibit prostate cancer cell growth and induce G1 phase cell-cycle arrest in precursor T-cell lymphoblastic leukemia/lymphoma cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 327033-36-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| SMIFH2 | SMIFH2. Group: Biochemicals. Grades: Purified. CAS No. 340316-62-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SMIFH2 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SMIFH2 | SMIFH2 is a formin specific inhibitor. SMIFH2 inhibits actin polymerization by Formins and affects the actin cytoskeleton. Uses: Designed for use in research and industrial production. Additional or Alternative Names: STK197413, ZINC01203437, SMIFH2, AC1M4GYW, MolPort-002-178-894, (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione, AKOS001651888, BIM-0040107.P001, (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione, 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione, 340316-62-3. Product Category: Inhibitors. Appearance: Solid. CAS No. 340316-62-3. Molecular formula: C15H9BrN2O3S. Mole weight: 377.21. Purity: 0.96. IUPACName: (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione. Canonical SMILES: C1=CC(=CC(=C1)Br)N2C(=O)C(=CC3=CC=CO3)C(=O)NC2=S. Product ID: ACM340316623. Alfa Chemistry ISO 9001:2015 Certified. | |
| SMIFH2 | SMIFH2 is a formin specific inhibitor. SMIFH2 inhibits actin polymerization by Formins and affects the actin cytoskeleton[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 340316-62-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16931. | |
| Smi I | One unit of the enzyme is the amount required to hydrolyze 1 μg of T7 DNA (SspI-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme >95% of the dna fragments can be ligated and recut. ligation >95% in presence of 10% peg. Group: Restriction Enzymes. Purity: 1000U; 5000U. ATTT↑AAAT TAAA↓TTTA. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer O, BSA. Storage: -20°C. Form: Liquid. Source: Streptococcus milleri S. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1177RE. | |
| Smilagenin | Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases [1]. Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density [2]. Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD [3]. Uses: Scientific research. Group: Natural products. CAS No. 126-18-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106353. | |
| Smilagenin | Smilagenin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (25R)-SPIROSTAN-3BETA-OL; 25R,5BETA-SPIROSTAN-3BETA-OL; ISOSARSAPOGENIN; (25R)-Spirostan-3.β.-ol; (25R)-5beta-spirostan-3beta-ol; ISOSARSAPOGENINE; ESMILAGENIN; SMILAGENIN; ISOSARSASAPOGENIN. Product Category: Steroidal Compounds. CAS No. 126-18-1. Molecular formula: C27H44O3. Mole weight: 416.64. Purity: 0.98. IUPACName: (25R)-5β-spirostan-3β-ol. Canonical SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)OC1. Density: 1.11g/cm³. ECNumber: 204-775-8. Product ID: ACM126181. Alfa Chemistry ISO 9001:2015 Certified. | |
| Smilagenin acetate | Smilagenin acetate is a sapogenin derivative extracted from patent US20030004147A1. Smilagenin acetate increases the expression of acetylcholine m2 receptors and can be used for the research of dementia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4947-75-5. Pack Sizes: 5 mg. Product ID: HY-N7421. | |
| Smilax sarsaparilla, ext. | Smilax sarsaparilla, ext. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Smilax sarsaparilla, ext.;SARSAPARILLA ROOT EXTRACT. Product Category: Heterocyclic Organic Compound. CAS No. 91770-66-0. Purity: 0.96. Product ID: ACM91770660. Alfa Chemistry ISO 9001:2015 Certified. | |
| SmiM I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. CAYNN↑NNRTG GTRNN↓NNYAC. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Sphingobacterium mizutae M. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; and 50% glycerol. Cat No: ET-1178RE. | |
| SMN-C3 | SMN-C3 is an orally active SMN2 splicing modulator and has the potential to treat spinal muscular atrophy (SMA). Uses: Scientific research. Group: Signaling pathways. CAS No. 1449597-34-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112633. | |
| Smo Antagonist, SA10 (4- ( (Benzo [c] [1, 2, 5] thiadiazole-4-sulfonamido) methyl -N- (3-phenylpropyl ) cyclohexane carboxamide) | SA10 inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 = 5uM). However, unlike SA1 and SA9, Smo antagonist SA10 does not directly bind to Smo. Inhibits the localization o Smo to cilia. Also treatment of Ptch1-/- MEFs with SA10 suppresses the beta-galactosidase activity (IC50 = 11.0uM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Smo Antagonist, SA1 (3-(3-(4-Fluorophenyl)-2, 5, 7-trimethylpyrazolo[1, 5a]pyrimidin-6-yl)-N-(4-(furan-2-yl)butan-2-yl)propanamide) | A Smoothened (Smo) antagonist. SA1 inhibits Hh pathway by interacting directly with Smo. Inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 = 3.1uM). Also inhibits the localization of Smo to cilia. Treatment of Ptch1-/- MEFs with SA1 suppresses the b-galactosidase activity (IC50 = 3.8uM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Smo Antagonist, SA9 (3- (3- (4-Fluorophenyl) -5-oxo-4, 5-dihydro-[1, 2, 4]triazolo[4, 3-a]quinazolin-1-yl-N- (3-methylphenethyl) propanamide) | SA9 inhibits Hh pathway by interacting directly with Smo. It inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 =19um). Induces the localization of Smo to cilia in ASZ1 cells, but not in IMCD3 cells. Also treatment of Ptch1-/- MEFs with SA9 suppresses the b-galactosidase activity (IC50 =1.0um) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| SMO-IN-2 | SMO-IN-2 (compound 1) is a potent smoothened (SMO) inhibitor with an IC 50 value of 123.4 nM for hedgehog (Hh) signaling pathway. SMO-IN-2 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1822355-27-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-150564. | |
| Smoke Point Standard | ASTM D 1322 / IP 57, 24.25 mm. Group: Cloud point standards. | |
| Smoke Tree Extract (Ratio) | Smoke Tree Extract (Ratio). Group: Others. Purity: 4:1~20:1. Smoke Tree Extract (Ratio). Cat No: EXTW-051. | |
| Smoothened Agonist, SAG - CAS 364590-63-6 | A cell-permeable Smoothened Agonist, SAG, CAS 364590-63-6, modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (KD = 59 nM). Group: Fluorescence/luminescence spectroscopy. | |
| Smoothened Agonist, SAG (N-Methyl-N- (3-pyridinylbenzyl) -N- (3-chlorobenzo [b]thiophene-2-carbonyl) -1, 4-diaminocyclohexane, SAG1.3 ) | A cell-permeable benzothiophene compound that modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (=59nM). Shown to induce Smo internalization. Shown to induce Hedgehog pathway activation (EC50= ?3nM in NIH 3T3-derived Shh-LIGHT2 cells) and counteracts Cyclopamine-KAAD inhibition of Smo. Reported to act as an activator at low concentrations and as an inhibitor at very high concentrations. Group: Biochemicals. Grades: Highly Purified. CAS No. 364590-63-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| SMPT | SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 112241-19-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-126405. | |
| SMS121 | SMS121 is a CD36 inhibitor with a KD values of about 5 μM. SMS121 reduces the uptake of lipids and inhibits cell viability in acute myeloid leukemia cells. SMS121 has antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163541. | |
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