Acetate Reductase Suppliers USA
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Product | Description | |
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Thioredoxin reductase peptide acetate Quick inquiry Where to buy Suppliers range | Thioredoxin reductase peptide acetate, derived from residues 53-67 in thioredoxin reductase (TrxR), is widely used in research on thioredoxin reductase. Synonyms: L-Tryptophylglycyl-L-leucylglycylglycyl-L-threonyl-L-cysteinyl-L-valyl-L-asparaginyl-L-valylglycyl-L-cysteinyl-L-isoleucyl-L-prolyl-L-lysine acetate salt; Trp-Gly-Leu-Gly-Gly-Thr-Cys-Val-Asn-Val-Gly-Cys-Ile-Pro-Lys acetate salt. Grades: ≥95%. Molecular formula: C68H110N18O20S2. Mole weight: 1563.84. | |
10-trans-Atorvastatin Acetonide tert-Butyl Ester Quick inquiry Where to buy Suppliers range | 10-trans-Atorvastatin Acetonide tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4S,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4S,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 1105067-90-0. Molecular formula: C40H47FN2O5. Mole weight: 654.81. | |
1,2-Diphenyl-3,5-pyrazolidinedione Quick inquiry Where to buy Suppliers range | 1,2-Diphenyl-3,5-pyrazolidinedione is a reactant used in organic synthesis such as in the the preparation of inhibitors of UDP-N-acetylenolpyruvyl glucosamine reductase. Group: Biochemicals. Grades: Highly Purified. CAS No. 2652-77-9. Pack Sizes: 250mg, 1g. Molecular Formula: C15H12N2O2, Molecular Weight: 252.27. US Biological Life Sciences. | Worldwide |
17-?(Acetyloxy)?-?3-?methoxy-pregna-?3,?5-?dien-?20-?one Quick inquiry Where to buy Suppliers range | 17-?(Acetyloxy)?-?3-?methoxy-pregna-?3,?5-?dien-?20-?one is a reactant used in the synthesis of progesterone derivatives as steroid 5α-?reductase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1054-64-4. Pack Sizes: 25mg, 250mg. Molecular Formula: C24H34O4, Molecular Weight: 386.52. US Biological Life Sciences. | Worldwide |
2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid Quick inquiry Where to buy Suppliers range | 2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 260784-21-2. Pack Sizes: 100mg, 1g. Molecular Formula: C16H11NO4S2, Molecular Weight: 345.39. US Biological Life Sciences. | Worldwide |
2-[2, 4-dibromo-6-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]phenoxy]-acetic Acid Quick inquiry Where to buy Suppliers range | 2-[2, 4-dibromo-6-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]phenoxy]-acetic Acid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 123021-81-8. Pack Sizes: 50mg, 500mg. Molecular Formula: C12H7Br2NO4S2, Molecular Weight: 453.13. US Biological Life Sciences. | Worldwide |
2-[2, 4-dichloro-6-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]phenoxy]-acetic Acid Quick inquiry Where to buy Suppliers range | 2-[2, 4-dichloro-6-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]phenoxy]-acetic Acid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 123021-78-3. Pack Sizes: 100mg, 1g. Molecular Formula: C12H7Cl2NO4S2, Molecular Weight: 364.22. US Biological Life Sciences. | Worldwide |
2-[[2-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-1-naphthalenyl]oxy]-acetic Acid Quick inquiry Where to buy Suppliers range | 2-[[2-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-1-naphthalenyl]oxy]-acetic Acid is an analog of 2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid (O859575). 2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 1348775-25-6. Pack Sizes: 25mg, 250mg. Molecular Formula: C16H11NO4S2, Molecular Weight: 345.39. US Biological Life Sciences. | Worldwide |
2-((4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid Quick inquiry Where to buy Suppliers range | An impurity of Rosuvastatin. Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: D-erythro-Hexonic acid, 2,4-dideoxy-3,5-O-(1-methylethylidene)-, acetate (9CI); Rosuvastatin Impurity 41. Grades: 99%. CAS No. 402508-35-4. Molecular formula: C11H18O6. Mole weight: 246.26. | |
2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester Quick inquiry Where to buy Suppliers range | 2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C32H37NO4. Mole weight: 499.64. | |
2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester Quick inquiry Where to buy Suppliers range | 2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C32H37NO4. US Biological Life Sciences. | Worldwide |
2- ( (4R, 6S) -6- ( (E) -2- (4- (4-Fluorophenyl) -2- (2-hydroxy-N, 2-dimethylpropyl sulfonamido) -6-isopropyl pyrimidin-5-yl) vinyl) -2, 2-dimethyl-1, 3-dioxan-4-yl) acetic Acid tert-Butyl Ester Quick inquiry Where to buy Suppliers range | 2- ( (4R, 6S) -6- ( (E) -2- (4- (4-Fluorophenyl) -2- (2-hydroxy-N, 2-dimethylpropyl sulfonamido) -6-isopropyl pyrimidin-5-yl) vinyl) -2, 2-dimethyl-1, 3-dioxan-4-yl) acetic Acid tert-Butyl Ester is an Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1714147-51-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C32H46FN3O7S. US Biological Life Sciences. | Worldwide |
2-((4S,6S)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid Quick inquiry Where to buy Suppliers range | 2-((4S,6S)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 2165770-84-1. Molecular formula: C10H19NO4. Mole weight: 217.27. | |
2-[[6-Bromo-1-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid Quick inquiry Where to buy Suppliers range | 2-[[6-bromo-1-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 123021-42-1. Pack Sizes: 50mg, 500mg. Molecular Formula: C16H10BrNO4S2, Molecular Weight: 424.29. US Biological Life Sciences. | Worldwide |
2-Bromo-5-fluoro-4-methylanisole Quick inquiry Where to buy Suppliers range | 2-Bromo-5-fluoro-4-methylanisole is being used in studies for the design and preparation of (arylcarbamoylphenoxy) acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications. Group: Biochemicals. Grades: Highly Purified. CAS No. 314298-15-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H8BrFO, Molecular Weight: 219.05. US Biological Life Sciences. | Worldwide |
2-Fluoro Atorvastatin tert-Butyl Ester Quick inquiry Where to buy Suppliers range | 2-Fluoro Atorvastatin tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6R)-6-(2-(2-(2-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6R)-6-[2-[2-(2-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 1099474-28-8. Molecular formula: C40H47FN2O5. Mole weight: 654.81. | |
2-((Z)-5-((E)-2-methyl-3-phenylallylidene)-2,4-dioxothiazolidin-3-yl)acetic acid Quick inquiry Where to buy Suppliers range | An impurity of Epalrestat, a carboxylic acid-based inhibitor of aldose reductase. Synonyms: 2-[5-((2E)-2-methyl-3-phenylprop-2-enylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]a cetic acid. CAS No. 794510-29-5. Molecular formula: C15H13NO4S. Mole weight: 303.3. | |
(3R,5S)-Atorvastatin Acetonide tert-Butyl Ester Quick inquiry Where to buy Suppliers range | (3R,5S)-Atorvastatin Acetonide tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl 1,3-Dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl (4R,6S)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate. CAS No. 947249-30-1. Molecular formula: C40H47FN2O5. Mole weight: 654.81. | |
5-Methoxyindole-3-acetonitrile-d2 Quick inquiry Where to buy Suppliers range | 5-Methoxyindole-3-acetonitrile-d2 is a labelled analogue of 5-Methoxyindole-3-acetonitrile (M262818), which is a versatile reactant used in the preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment. It is also used in the synthesis of carboline analogs as potent MAPKAP-K2 inhibitors. 5-Methoxyindole-3-acetonitrile-d2 is also an intermediate in synthesizing Melatonin-d4 (M215002), a hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation / metastasis of breast cancer cells by inhibiting estrogen receptor action. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C11H8D2N2O. US Biological Life Sciences. | Worldwide |
Alrestatin Quick inquiry Where to buy Suppliers range | Alrestatin is an inhibitor of aldose reductase (IC50 = 148 μM). Uses: Specific inhibitor of aldose reductase. Synonyms: Alrestatine; 2-(1,3-dioxobenzo[de]isoquinolin-2-yl)acetic acid. Grades: ≥98%. CAS No. 51411-04-2. Molecular formula: C14H9NO4. Mole weight: 255.23. | |
Alrestatin (sodium) Quick inquiry Where to buy Suppliers range | Alrestatin sodium is a specific inhibitor of aldose reductase (IC50 = 148 μM). Uses: A specific inhibitor of aldose reductase. Synonyms: Sodium;2-(1,3-dioxobenzo[de]isoquinolin-2-yl)acetate. Grades: ≥98%. CAS No. 51876-97-2. Molecular formula: C14H8NNaO4. Mole weight: 277.21. | |
Atorvastatin acetonide methyl ester Quick inquiry Where to buy Suppliers range | Atorvastatin acetonide methyl ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: Methyl [(4R,6R)-6-{2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate; methyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 1353049-81-6. Molecular formula: C37H41FN2O5. Mole weight: 612.73. | |
Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6S)-Isomer Quick inquiry Where to buy Suppliers range | Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6S)-Isomer is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6S)-6-(Cyanomethyl)-2,2-dimethyl--1,3-dioxane-4-acetic Acid tert-Butyl Ester; (4R-trans)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 196085-84-4. Molecular formula: C14H23NO4. Mole weight: 269.34. | |
Auranofin Quick inquiry Where to buy Suppliers range | Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA, as an inhibitor of thioredoxin reductase (TrxR) (IC50 = 20 nM; Ki = 4 nM for the NADPH-reduced form of human cytosolic TrxR). Uses: Auranofin inhibits various leukocyte activation pathways at multiple sites. Synonyms: SKF-39162; SKF-D-39162; SKF 39162; SKF D 39162; SKFD-39162; SKFD39162; Ridaura; NSC 321521, Ridauragold thiol; Gold, [1-(thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-; [1-(Thio-κS)-β-D-glucopyranose 2, 3, 4, 6-tetraacetato] (triethylphosphine)gold; Gold, (1-thio-β-D-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate; Gold, (1-thio-β-D-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-; β-D-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex; [ (Tetra-O-acetyl-β -D-glucopyranosyl)thio] (triethylphosphine)gold; Aktil; Crisinor; Crisofin Gold Salt; Ridauran; SKF 39162D. Grades: ≥98%. CAS No. 34031-32-8. Molecular formula: C20H34AuO9PS. Mole weight: 678.49. | |
Caracemide Quick inquiry Where to buy Suppliers range | Caracemide is an agent derived from acetohydroxamic acid. It has potential antineoplastic activity. Caracemide can inhibit ribonuclease reductase, resulting in decreased DNA synthesis and tumor growth. But in Feb 1995, Phase II for Cancer in USA was discontinued. Uses: Cancer. Synonyms: NSC 253272; NSC253272; NSC-253272; N-(methylcarbamoyl)-N-((methylcarbamoyl)oxy)acetamide. Grades: 98%. CAS No. 81424-67-1. Molecular formula: C6H11N3O4. Mole weight: 189.17. | |
Cochlioquinone B Quick inquiry Where to buy Suppliers range | It is the minor component of a bioactive pigment isolated from Bipolaris cynodontis and Cochliobolus miyabeanus. It is an NADH-ubiquinone reductase inhibitor. It is also a phytotoxic agent inhibiting root growth. It is closely related to cochlioquinone A which inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. It is an antagonist of the human chemokine receptor, CCR5, in HIV-1. Synonyms: 20-De(acetyloxy)-11-deoxy-20-oxo-cochlioquinone A; 9-(1, 3-Dimethyl-2-oxopentyl)-1, 2, 3, 4aα, 5, 6, 6a, 12, 12aα, 12b-decahydro-3β-(1-hydroxy-1-methylethyl)-6aβ, 12bβ-dimethyl-pyrano[3, 2-a]xanthene-8, 11-dione Stereoisomer; (3R,4aR,6aR,12aR,12bR)-9-[(1S,3S)-1,3-Dimethyl-2-oxopentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethylpyrano[3,2-a]xanthene-8,11-dione. Grades: >99% by HPLC. CAS No. 32450-26-3. Molecular formula: C28H40O6. Mole weight: 472.61. | |
Difluoro Atorvastatin Acetonide tert-Butyl Ester Quick inquiry Where to buy Suppliers range | Difluoro Atorvastatin Acetonide tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6R)-6-(2-(2,3-bis(4-fluorophenyl)-5-isopropyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6R)-6-[2-[2,3-Bis(4-fluorophenyl)-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 693793-87-2. Molecular formula: C40H46F2N2O5. Mole weight: 672.8. | |
Epalrestat (E, E)-Isomer Quick inquiry Where to buy Suppliers range | A stereoisomer of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: 2-((Z)-5-((Z)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. Grades: > 95%. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
Epalrestat (Z, Z)-Isomer Quick inquiry Where to buy Suppliers range | A stereoisomer of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: 2-((Z)-5-((Z)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. Grades: > 95%. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
ethyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Quick inquiry Where to buy Suppliers range | ethyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: RYW6GR2YSQ; UNII-RYW6GR2YSQ; 616201-27-5; 1,3-Dioxane-4-acetic acid, 6-(2-(2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-, ethyl ester, (4R,6R)-; Ethyl (4R,6R)-6-(2-(2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxane-4-acetate; SCHEMBL915488. CAS No. 616201-27-5. Molecular formula: C38H43FN2O5. Mole weight: 626.77. | |
Finasteride acetate Quick inquiry Where to buy Suppliers range | Finasteride acetate is a specific inhibitor of 5α-reductase. Finasteride can be used in the treatment of men with benign prostatic, and through the assessment of the long-term safety and efficacy of finasteride hyperplasia (BPH) it was well tolerated, wit. Synonyms: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide;acetic acid Finasteride (acetate). CAS No. 222989-99-3. Molecular formula: C25H40N2O4. Mole weight: 432.60. | |
FR901512 Quick inquiry Where to buy Suppliers range | FR901512, a new specific inhibitor of HMG-CoA reductase, is isolated from the culture of an agonomycetous fungus No. 14919. FR901512 inhibits cholesterol synthesis from [14C] acetate in Hep G2 cells. Synonyms: 6-Heptenoic acid, 7-[(6R,8S)-8-(acetyloxy)-5,6,7,8-tetrahydro-2,6-dimethyl-1-naphthalenyl]-3,5-dihydroxy-, (3R,5S,6E)-; (3R,5S,E)-7-((6R,8S)-8-acetoxy-2,6-dimethyl-5,6,7,8-tetrahydronaphthalen-1-yl)-3,5-dihydroxyhept-6-enoic acid. CAS No. 151606-25-6. Molecular formula: C21H28O6. Mole weight: 376.44. | |
isopropyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Quick inquiry Where to buy Suppliers range | isopropyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: 1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1-methylethyl ester, (4R,6R)-; propan-2-yl 2-[(4R,6R)-6-[2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate; Isopropyl Acetonide Atorvastatin; SCHEMBL12665703; DTXSID601099894; 1-Methylethyl (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate. CAS No. 1112262-71-1. Molecular formula: C39H45FN2O5. Mole weight: 640.78. | |
Lipid Metabolism Compound Library Quick inquiry Where to buy Suppliers range | A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS). - Covers several important targets, key components in lipid metabolism pathway, such as Acetyl-CoA Carboxylase?Acyltransferase?cholesteryl ester transfer protein (CETP)?FAAH?Fatty Acid Synthase (FASN)?HMG-CoA Reductase (HMGCR), etc. - Detailed compound information with structure, target, and biological activity description. - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2510. Categories: Lipid Metabolism Compounds Libraries. | |
Pitavastatin Impurity 20 Quick inquiry Where to buy Suppliers range | Pitavastatin Impurity 20 is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Uses: A hmg-coa reductase inhibitor intermediate. Synonyms: (4R-cis)-6-Chloromethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester; tert-butyl syn-(3R,5S)-6-chloro-3,5-(isopropylidenedioxy)-hexanoate; (4R-cis)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid; t-butyl (4R-cis)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxan-4-ylacetate; (4R,6S)-6-(Chloromethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. Grades: 96%. CAS No. 154026-94-5. Molecular formula: C13H23ClO4. Mole weight: 278.77. | |
Pitavastatin Impurity 5 Quick inquiry Where to buy Suppliers range | Pitavastatin Impurity 5 is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate; (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester; Pitavastatin Impurity 21. Grades: 98%. CAS No. 147489-06-3. Molecular formula: C32H36FNO4. Mole weight: 517.63. | |
Ponalrestat Quick inquiry Where to buy Suppliers range | Ponalrestatis an aldose reductase inhibitor originator byAstraZeneca. It can block the conversion of glucose to sorbitol. Ponalrestatis shows selectivity for aldose reductase 2 over aldose reductase 1 with Ki values of 7.7 nM and 60 μM. Phase III for the treatment of diabetes was discontinued. Uses: Diabetes. Synonyms: Ponalrestat, ICI-128436; ICI 128436; ICI128436; MK-538; MK 538; MK538. Brand name: Statil; Statyl. QJ0339; QJ0339; QJ-0339; 2-(3-(4-bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid. Grades: 98%. CAS No. 72702-95-5. Molecular formula: C17H12BrFN2O3. Mole weight: 391.20. | |
Rosuvastatin Impurity 12 Quick inquiry Where to buy Suppliers range | An impurity of Rosuvastatin. Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: SCHEMBL1021914; SCHEMBL1022804; 2-((4R,6S)-6-((E)-2-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid; 894787-93-0. Grades: 95%. CAS No. 894787-93-0. Molecular formula: C25H32FN3O6S. Mole weight: 521.60. | |
Sclerotiorin Quick inquiry Where to buy Suppliers range | Antibiotic. Antibacterial. Weak antagonist of human endothelin receptor A (ETA) and B (ETB). Cholesteryl ester transfer protein (CETP) activity inhibitor. Grb2-Shc binding inhibitor. Potent aldose reductase inhibitor. Potent reversible, non-competitive soybean lipoxygenase-1 (LOX-1) inhibitor. Antioxidant. Free radical scavenger. Antifungal. Group: Biochemicals. Alternative Names: (S-(R*,R*-(E,E)))-Sclerotiorin, 7-(acetyloxy)-5-chloro-3-[(1E,3E,5S)-3,5-dimethyl-1,3-heptadien-1-yl]-7-methyl-6H-2-benzopyran-6,8(7H)-dione. Grades: Highly Purified. CAS No. 549-23-5. Pack Sizes: 500ug, 1mg, 5mg. Molecular Formula: C21H23ClO5, Molecular Weight: 390.9. US Biological Life Sciences. | Worldwide |
Simvastatin EP Impurity B Quick inquiry Where to buy Suppliers range | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Acetyl simvastatin; 4'-Acetyl Simvastatin; Simvastatin Acetate; Simvastatin acetate ester; Simvastatin USP Related Compound B. Grades: 95%. CAS No. 145576-25-6. Molecular formula: C27H40O6. Mole weight: 460.62. | |
Sulfobromophthalein Sodium (BSP) Quick inquiry Where to buy Suppliers range | Sulfobromophthalein disodium salt hydrate has been used as a positive control to study the interaction of 11-keto- β-boswellic acid (KBA) and 3-acetyl-11-keto- β-boswellic acid (AKBA) with organic anion transporter OATP1B3. Sulfobromophthalein (BSP) is a high affinity organic ion substrate for organic anion transporting polypeptides (OATPs) and has been used as a substrate for multidrug resistance associated protein 2 (Mrp2). BSP is transported into hepatocytes by OATPs and, after conjugation to glutathione, is excreted into bile by Mrp2. It was found to inhibit the aldo-keto reductase ARK1C20. Group: Biochemicals. Alternative Names: Bromsulfalein disodium salt hydrate; Bromothalein disodium salt hydrate; Sulfobromophthalein disodium salt hydrate; BSP; disodium 2-hydroxy-5-1z-4-oxo-3-sulfonatocyclohexa-2,5-dien-1-ylidene 2,3,4,5-tetrabromo-6-carboxyphenyl methyl benzenesulfonate tetrahydrate. Grades: Highly Purified. CAS No. 123359-42-2. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C20H8Br4O10S2ยท2Na, Molecular Weight: 837.99. US Biological Life Sciences. | Worldwide |
tert-butyl 2-((4R,6R)-6-(2-(1-(2-((4R,6R)-6-(2-(tert-butoxy)-2-oxoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)ethyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Quick inquiry Where to buy Suppliers range | tert-butyl 2-((4R,6R)-6-(2-(1-(2-((4R,6R)-6-(2-(tert-butoxy)-2-oxoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)ethyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 1229658-18-7. Molecular formula: C48H67FN2O9. Mole weight: 835.07. | |
tert-butyl 2-((4R,6R)-6-(2-(2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Quick inquiry Where to buy Suppliers range | tert-butyl 2-((4R,6R)-6-(2-(2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: 2-Methyl-2-propanyl {(4R,6R)-6-[2-({[(4R,6R)-6-{2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetyl}amino)ethyl]-2,2-dimethyl-1,3-d ioxan-4-yl}acetate; 1,1-Dimethylethyl (4R,6R)-6-[2-[[2-[(4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetyl]amino]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate. CAS No. 1116118-82-1. Molecular formula: C50H64FN3O8. Mole weight: 854.06. | |
tert-butyl 2-((4R,6R)-6-(2-(2-((4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Quick inquiry Where to buy Suppliers range | tert-butyl 2-((4R,6R)-6-(2-(2-((4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 2299304-89-3. Molecular formula: C24H44N2O7. Mole weight: 472.62. | |
tert-butyl 2-((4R,6R)-6-(2-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Quick inquiry Where to buy Suppliers range | tert-butyl 2-((4R,6R)-6-(2-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 1371615-55-2. Molecular formula: C47H60FN3O8. Mole weight: 814.01. | |
tert-butyl 2-((4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Quick inquiry Where to buy Suppliers range | tert-butyl 2-((4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate; (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-Dimethylethyl Ester, (4R-cis)-. CAS No. 125971-94-0. Molecular formula: C14H23NO4. Mole weight: 269.34. | |
tert-Butyl 2-[(4R,6S)-2,2-Dimethyl-6-[(1-phenyl-1H-terazol-5-ylsulfonyl)methyl]-1,3-dioxan-4-yl]acetate Quick inquiry Where to buy Suppliers range | A heterocyclic-substituted dihydroxyheptenoic acid as an HMG-CoA reductase inhibitor. Synonyms: 2,4,6-Trideoxy-3,5-O-(1-methylethylidene)-6-[(1-phenyl-1H-tetrazol-5-yl)sulfonyl]-D-erythro-hexanoic Acid 1,1-Dimethylethyl Ester. Grades: 97%. CAS No. 380460-37-7. Molecular formula: C20H28N4O6S. Mole weight: 452.52. | |
tert-butyl 2-((4R,6S)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Quick inquiry Where to buy Suppliers range | tert-butyl 2-((4R,6S)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 2088732-01-6. Molecular formula: C14H27NO4. Mole weight: 273.37. | |
tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Quick inquiry Where to buy Suppliers range | tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate; 2,4-Dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonic Acid 1,1-Dimethylethyl Ester; (4R,6S)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 2-[(4R,6S)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic Acid tert-Butyl Ester. CAS No. 124655-09-0. Molecular formula: C13H24O5. Mole weight: 260.33. | |
Tolrestat Quick inquiry Where to buy Suppliers range | Tolrestat is an orally active and potent aldose reductase inhibitor with IC50 value of 35 nM. It was approved for the control of certain diabetic complications. It reduces RBC (red blood cells) sorbitol levels in rats. It decreased, in dose-related manner, the RBC sorbitol levels in normal and in streptozotocin diabetic rats. It failed a Phase III trial in the U.S. due to toxicity. It was discontinued by Wyeth in 1997 because of the risk of severe liver toxicity and death. It was sold under the tradename Alredase. Uses: Tolrestat was approved for the control of certain diabetic complications. Synonyms: AY 27773; AY-27773; AY27773; Tolrestat; AY-27,773; AY 27,773; AY27,773; Alredase; Tolrestatum; Lorestat;2-[[6-methoxy-5-(trifluoromethyl)naphthalene-1-carbothioyl]-methylamino]acetic acid;N-[[6-Methoxy-5-(triiquoromethyl)-1-naphthalenyl]thioxomethyl]-N-methylglyeine. Grades: 95%. CAS No. 82964-04-3. Molecular formula: C16H14F3NO3S. Mole weight: 357.35. | |
Uridine 5'-Diphospho-N-Acetylquinovosamine Disodium Salt Quick inquiry Where to buy Suppliers range | Uridine 5'-Diphospho-N-Acetylquinovosamine, an analogue of FlaA1, is a bifunctional UDP-GlcNAc C6 dehydratase?/C4 reductase from Helicobacter pylori. Synonyms: Uridine 5'-(Trihydrogen diphosphate) P'-[2-(Acetylamino)-2,6-dideoxy-α-D-glucopyranosyl] Ester Disodium Salt; UDP-N-acetylquinovosamine Disodium Salt; UDP-α-N-acetylquinovosamine Disodium Salt. CAS No. 131564-52-8. Molecular formula: C17H25N3Na2O16P2. Mole weight: 635.32. | |
Zenarestat Quick inquiry Where to buy Suppliers range | Zenarestat is an aldose reductase inhibitor. It was investigated as a treatment of diabetic neuropathy and cataract. It was developed by Fujisawa Pharmaceutical Co Ltd and was terminated in clinic phase 3 trials. Uses: Zenarestat was investigated as a treatment of diabetic neuropathy and cataract. Synonyms: FR 74366; FR74366 FR-74366; CI-1014; FK-366; CI1014; FK366; FK 366; FK-366; Zenarestat;2-[3-[(4-bromo-2-fluorophenyl)methyl]-7-chloro-2,4-dioxoquinazolin-1-yl]acetic acid;FR74366;3-(2-Fluoro-4-bromobenzyl)-7-chloro-2,4(1H,3H)-dioxoquinazoline-1-acetic acid;3-[(4-Bromo-2-fluorophenyl)methyl]-7-chloro-3,4-dihydro-2,4-dioxo-1(2H)-quinazolineacetic acid. Grades: 95%. CAS No. 112733-06-9. Molecular formula: C17H11BrClFN2O4. Mole weight: 441.64. | |
Zopolrestat Quick inquiry Where to buy Suppliers range | Zopolrestat is an inhibitor of Aldose Reductase(AR). It has been shown to play roles in inflammation and cancer. It is used for the treatment of diabetic nephropathy and cardiac disease. It was developed by Pfizer and was terminated in clinic phase 2 trials. Uses: Zopolrestat is used for the treatment of diabetic nephropathy and cardiac disease. Synonyms: 3-[(5-Trifluoromethyl-2-benzothiazolyl)methyl]-3,4-dihydro-4-oxophthalazine-1-acetic acid;CP-73850;3,4-Dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]-1-phthalazineacetic acid;Alond;Xedia;2-[4-Oxo-3-[[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl]phthalazin-1-yl]acetic acid;CP 73850; CP73850; CP-73850; Zopolrestat; Zopolrestatum. Grades: 95%. CAS No. 110703-94-1. Molecular formula: C19H12F3N3O3S. Mole weight: 419.38. |