Acid Cyclooxygenase Suppliers USA
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Product | Description | |
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1-(2-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 1-(2-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester is an intermediate used to prepare 4-Dechloro-2-chloroindomethacin (D226240), an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). Group: Biochemicals. Grades: Highly Purified. CAS No. 1568-35-0. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H18ClNO4. US Biological Life Sciences. | Worldwide |
12(S)-HHTrE Quick inquiry Where to buy Suppliers range | 12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of human platelets. It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. Synonyms: 12(S)-HHT; 12-hydroxyheptadecatrienoic acid. Grades: ≥95%. CAS No. 54397-84-1. Molecular formula: C17H28O3. Mole weight: 280.4. | |
1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester is an intermediate used to prepare 3-Chloroindomethacin (C367395), an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). Group: Biochemicals. Grades: Highly Purified. CAS No. 942431-82-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H17Cl2NO4, Molecular Weight: 406.26. US Biological Life Sciences. | Worldwide |
1-(3-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 1-(3-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester is an intermediate used to prepare 4-Dechloro-3-chloroindomethacin (D226245), an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). Group: Biochemicals. Grades: Highly Purified. CAS No. 1568-36-1. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H18ClNO4. US Biological Life Sciences. | Worldwide |
1-(4-sec-Butylphenyl)ethanone Quick inquiry Where to buy Suppliers range | 1-(4-sec-Butylphenyl)ethanone is a useful synthetic intermediate in the synthesis of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000) which is a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Biochemicals. Grades: Highly Purified. CAS No. 7645-81-0. Pack Sizes: 1g, 10g. Molecular Formula: C12H16O, Molecular Weight: 176.25. US Biological Life Sciences. | Worldwide |
15-Keto Prostaglandin E2 Quick inquiry Where to buy Suppliers range | 15-Keto Prostaglandin E2 is a lipid compound derived from arachidonic acid by the action of cyclooxygenases. Prostaglandins act locally as messenger molecules in a variety of physiological processes. Group: Biochemicals. Grades: Highly Purified. CAS No. 26441-05-4. Pack Sizes: 10mg, 25mg. Molecular Formula: C20H30O5, Molecular Weight: 350.45. US Biological Life Sciences. | Worldwide |
1-Isopropyl Etodolac Quick inquiry Where to buy Suppliers range | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 8-Ethyl-1,3,4,9-tetrahydro-1-(1-methylethyl)-Pyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 849630-65-5. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
1-Propyl Etodolac Quick inquiry Where to buy Suppliers range | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1-Ethyl-1,3,4,9-tetrahydro-8-(1-methylethyl)-Pyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 57816-83-8. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid Quick inquiry Where to buy Suppliers range | 20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid is a potent vasoconstrictor produced in vascular smooth muscle cells. Its EC50 value is < 10 nM. It is a cytochrome P450 metabolite. It induces diuresis by inhibiting Na+-K+-ATPase in proximal tubules and Na+/K+/Cl+ cotransporter in the thick ascending limb of Henle's loop in kidney. It is involved in the regulation of sodium, potassium, and chloride transport in the renal tubules. It is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction in rat cerebral microvessels. It is excreted mainly as the glucuronide conjugate. It can be further metabolized by cyclooxygenase to 20-hydroxy PGG2 and 20-hydroxy PGH2. It regulates blood pressure in a complex way. It sensitizes smooth muscle cells to the constrictor stimuli and promotes the proliferation of endothelial cells. It has the ability to induce proinflammatory changes. It blocked the 70 pS K+ channel localized in the apical membrane in TALH cells. It was found to be a potent vasoconstrictor through activating the kinase pathways that contribute to the vascular tone regulation including MAPK, PKC, rho kinase and src-type tyrosine kinase. It may similarly regulate blood pressure and contribute to the development of stroke and heart attacks. Synonyms: 20-Hydroxyeicosatetraeonic acid; 20 Hydroxyeicosatetraeonic acid; 20Hydroxyeicosatetraeonic acid; 20HETE; 20 HETE; 20-HETE;(5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid;20-Hydroxyeicosatetraenoic acid;20-hydroxy-5,8,11,14-eicosatetraenoic acid. Grades: >98%. CAS No. 79551-86-3. Molecular formula: C20H32O3. Mole weight: 320.47. | |
2,?2'-?[(3,?3',?5,?5'-Tetrachloro[1,?1'-?biphenyl]?-?4,?4'-?diyl)?diimino]?bis-benzeneacetic Acid Quick inquiry Where to buy Suppliers range | 2,?2'-?[(3,?3',?5,?5'-Tetrachloro[1,?1'-?biphenyl]?-?4,?4'-?diyl)?diimino]?bis-benzeneacetic Acid is an impurity of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound and a cyclooxygenase (COX) inhibitor (1,2,3). Diclofenac exhibits anti-inflammatory, analgesic, and antipyretic properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 1609187-32-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C28H20Cl4N2O4, Molecular Weight: 590.28. US Biological Life Sciences. | Worldwide |
2-?[(2,?6-Dichloro-?4-?oxo-?2,?5-?cyclohexadien-?1-?ylidene)?amino]?-benzeneacetic Acid Quick inquiry Where to buy Suppliers range | 2-?[(2,?6-Dichloro-?4-?oxo-?2,?5-?cyclohexadien-?1-?ylidene)?amino]?-benzeneacetic Acid is a related compound of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound and a cyclooxygenase (COX) inhibitor (1,2,3). Diclofenac exhibits anti-inflammatory, analgesic, and antipyretic properties. 2-?[(2,?6-Dichloro-?4-?oxo-?2,?5-?cyclohexadien-?1-?ylidene)?amino]?-benzeneacetic Acid can be used to study cytochrome P 450 isoforms involved in the bioactivation of diclofenac to reactive p-benzoquinone imines (4). Group: Biochemicals. Grades: Highly Purified. CAS No. 928343-25-3. Pack Sizes: 500ug, 1mg. Molecular Formula: C14H9Cl2NO3, Molecular Weight: 310.13. US Biological Life Sciences. | Worldwide |
2-Bromomethyl-6-nitrobenzoic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 2-Bromomethyl-6-nitrobenzoic Acid Methyl Ester is a potential cyclooxygenase inhibitor derived from thalidomide (T338850), an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma. Group: Biochemicals. Alternative Names: Methyl 2-(2-Bromomethyl)-6-nitrobenzoate; Methyl 2-(Bromomethyl)-6-nitrobenzoate. Grades: Highly Purified. CAS No. 61940-21-4. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
2-Cyano-3,3-diphenylacrylic Acid Quick inquiry Where to buy Suppliers range | 2-Cyano-3,3-diphenylacrylic Acid was used to study skin-permeable selective cyclooxygenaswe-2 inhibitor composition, and to study hydrophilic components of cosmetic compositions, such as in sunscreen. Group: Biochemicals. Grades: Highly Purified. CAS No. 10380-41-3. Pack Sizes: 100mg, 500mg. Molecular Formula: C16H11NO2, Molecular Weight: 249.26. US Biological Life Sciences. | Worldwide |
2-(p-sec-Butylphenyl)propionic Acid Quick inquiry Where to buy Suppliers range | 2-(p-sec-Butylphenyl)propionic Acid (Ibuprofen EP Impurity O) is an impurity of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Biochemicals. Grades: Highly Purified. CAS No. 64451-76-9. Pack Sizes: 250mg, 2.5g. Molecular Formula: C13H18O2, Molecular Weight: 206.28. US Biological Life Sciences. | Worldwide |
2-(p-sec-Butylphenyl)propionic Acid-d3 Quick inquiry Where to buy Suppliers range | 2-(p-sec-Butylphenyl)propionic Acid-d3 is the isotope labelled analog of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000) which is a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C13H15D3O2, Molecular Weight: 209.3. US Biological Life Sciences. | Worldwide |
3-(7-Ethyl-3-(2-hydroxyethyl)-1H-indol-2-yl)pent-2-enoic Acid Quick inquiry Where to buy Suppliers range | 3-(7-Ethyl-3-(2-hydroxyethyl)-1H-indol-2-yl)pent-2-enoic Acid is a a double bond isomer of Etodolac Impurity L which is an impurity of Etodolac (racemic, E933100), a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2). Etodolac displays anti-inflammatory effects in both adjuvant arthritic and normal rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C17H21NO3, Molecular Weight: 287.35. US Biological Life Sciences. | Worldwide |
4-Hydroxy Diclofenac-13C6 (contain 3% unlabeled) Quick inquiry Where to buy Suppliers range | 13C Labeled Diclofenac Sodium Salt is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Alternative Names: 2-[ (2, 6-Dichloro-4-hydroxyphenyl)amino] (benzene-13C6)acetic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
6-Hydroxy Etodolac Quick inquiry Where to buy Suppliers range | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1,8-Diethyl-1,3,4,9-tetrahydro-6-hydroxypyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 101901-06-8. Molecular formula: C17H21NO4. Mole weight: 303.36. | |
8-Isopropyl Etodolac Quick inquiry Where to buy Suppliers range | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1-Ethyl-1,3,4,9-tetrahydro-8-(1-methylethyl)-pyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 57917-63-2. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
8-Propyl Etodolac Quick inquiry Where to buy Suppliers range | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1-Ethyl-1,3,4,9-tetrahydro-8-propyl-pyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 57817-27-3. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
Acetylsalicylic Acid Impurity E Quick inquiry Where to buy Suppliers range | Sasapyrine (salsalate) is a nonsteroidal oral anti-inflammatory agent.Relative to other NSAIDs, salsalate has a weak inhibitory effect on the cyclooxygenase enzyme and decreases the production of several pro inflammatory chemical signals such as interleukin-6, TNF-alpha, and C-reactive protein. Synonyms: NSC-49171. Grades: >98%. CAS No. 552-94-3. Molecular formula: C14H10O5. Mole weight: 258.23. | |
AKR1C3 Inhibitor (3- (4- (Trifluoromethyl) phenylamino) benzoic Acid) Quick inquiry Where to buy Suppliers range | A cell-permeable 3-phenyl-aminobenzoate compound that acts as a potent, competitive, reversible, active-site targeting inhibitor of aldo-keto reductase 1C3 (AKR1C3; type 5 17b-hydroxysteroid dehydrogenase) (IC50 = 60nM) with excellent selectivity over other closely related human AKR isoforms (IC50 = 22.7, 15.4, 62.7, >50, and >50uM for and AKR1C1, AKR1C2, AKR1C4, AKR1B1 and AKR1B10, respectively. Exhibits a weak inhibitory effect on cyclooxygenase 1 and 2 (IC50 = 100uM). Shown to efficiently block the AKR1C3-mediated production of testosterone in LNCaP-AKR1C3 cells (~10uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Apricoxib Quick inquiry Where to buy Suppliers range | Apricoxib is an orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. Synonyms: CS-701; CS 701; CS701; TG01; TG 01; TG-01; R-109339, R 109339; R109339; Benzenesulfonamide, 4-[2-(4-ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]-. CAS No. 197904-84-0. Molecular formula: C19H20N2O3S. Mole weight: 356.44. | |
BW 755C Quick inquiry Where to buy Suppliers range | Constitutive cyclooxygenase (COX-1) is present in cells under physiological conditions, whereas COX-2 is induced by some cytokines, mitogens, and endotoxin in pathological conditions, such as inflammation. Since 5-lipoxygenase (5-LO) oxidizes arachidonic acid to 5-hydroperoxyeicosatetraenoic acid. BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways. It inhibits 5-LO with IC50s of 0.75 μM, COX-1 with IC50s of 0.65 μg/ml, and COX-2 with IC50s of 1.2 μg/ml. BW 755C may also inhibit other LO pathways in vivo. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: BW755C; BW-755C; 1H-Pyrazol-3-amine, 4,5-dihydro-1-[3-(trifluoromethyl)phenyl]-; 4,5-Dihydro-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-amine; 1-(3-Trifluoromethylphenyl)-4,5-dihydro-1H-pyrazol-3-amine; 3-Amino-1-[3-(trifluoromethyl)phenyl]-2-pyrazoline; 3-Amino-1-[3-(trifluoromethyl)phenyl]pyrazoline; 3-Amino-1-[m-(trifluoromethyl)phenyl]-2-pyrazoline; Compound BW 755C. Grades: ≥95%. CAS No. 66000-40-6. Molecular formula: C10H10F3N3. Mole weight: 229.20. | |
Dexibuprofen lysine Quick inquiry Where to buy Suppliers range | Dexibuprofen is a Cyclooxygenase inhibitor originated by Gebro Pharma GmbH. It is a non-steroidal anti-inflammatory drug as the active dextrorotatory enantiomer of ibuprofen. Dexibuprofen can be used for the treatment of Postoperative pain. Uses: Postoperative pain. Synonyms: Dexibuprofen lysine; Doctrin; L 669455; L-669,455; Dexibuprofen lysine; MK 233; MK233; MK-233; UNII-T179MT9211; (+)-(S)-p-Isobutylhydratropic acid, compound with L-lysine (1:1), monohydrate. Grades: 95%. CAS No. 141505-32-0. Molecular formula: C19H34N2O5. Mole weight: 370.48. | |
Diclofenac Acyl- β-D-glucuronide Allyl Ester Quick inquiry Where to buy Suppliers range | Diclofenac Sodium Salt is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Alternative Names: 1-[2-[ (2, 6-Dichlorophenyl) amino]benzeneacetate]- β-D-glucopyranuronic Acid 2-Propen-1-yl Ester. Grades: Highly Purified. CAS No. 698358-10-0. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
Diclofenac Acyl Glucuronide (1-O-[2-[ (2, 6-Dichlorophenyl) amino) ]phenylacetyl]-b-D-glucopyranuronic Acid) Quick inquiry Where to buy Suppliers range | A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound an cyclooxygenase (COX) inhibitor. Group: Biochemicals. Alternative Names: 1-O-[2-[ (2, 6-Dichlorophenyl) amino) ]phenylacetyl]-b-D-glucopyranuronic Acid. Grades: Highly Purified. CAS No. 64118-81-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Diclofenac Carboxylic Acid (Diclofenac Metabolite) Quick inquiry Where to buy Suppliers range | 13C Labeled Diclofenac Sodium Salt is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Alternative Names: 2-[ (2, 6-Dichlorophenyl) amino]benzoic Acid; N- (2, 6-Dichlorophenyl) anthranilic Acid. Grades: Highly Purified. CAS No. 13625-57-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Diclofenac Ethyl Ester Quick inquiry Where to buy Suppliers range | 13C Labeled Diclofenac Sodium Salt is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Alternative Names: 2-[ (2, 6-Dichlorophenyl) amino]benzeneacetic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 15307-77-4. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
Diclofenac Methyl Ester Quick inquiry Where to buy Suppliers range | 13C Labeled Diclofenac Sodium Salt is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Alternative Names: 2-[ (2, 6-Dichlorophenyl) amino]benzeneacetic Acid Methyl Ester; [o- (2, 6-Dichloroanilino) phenyl]acetic Acid Methyl Ester; Methyl 2- (2, 6-Dichloroanilino) phenylacetate. Grades: Highly Purified. CAS No. 15307-78-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
Diclofenac Potassium Quick inquiry Where to buy Suppliers range | Diclofenac potassium is a nonsteroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in certain conditions. It is a competitive inhibitor of cyclooxygenase (COX) that suppresses the production of prostaglandins. Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade. Uses: Nsaid. Synonyms: 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Potassium Salt; [o-(2,6-Dichloroanilino)phenyl]acetic Acid Monopotassium Salt; 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monopotassium Salt; Caflam; Cataflam; K-fenak; Potassium diclofenac. Grades: >98%. CAS No. 15307-81-0. Molecular formula: C14H10Cl2KNO2. Mole weight: 334.24. | |
Diclofenac Sodium Salt (2- ( (2, 6-Dichlorophenyl) aminobenzeneacetic Acid) Quick inquiry Where to buy Suppliers range | A nonsteroidal anti-inflammatory compound an cyclooxygenase (COX) inhibitor. Group: Biochemicals. Alternative Names: 2- ( (2, 6-Dichlorophenyl) aminobenzeneacetic Acid. Grades: Highly Purified. CAS No. 15307-79-6. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
Dipyrone Quick inquiry Where to buy Suppliers range | Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models. Group: Biochemicals. Alternative Names: 1- [ (2, 3-Dihydro-1, 5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl) methylamino] methanesulfonic Acid Sodium Salt; (Antipyrinyl methyl amino) methanesulfonic Acid Sodium Salt; ARPF; Algocalmin; Algopyrin; Anador; Analgin; Analgine; Andolor; Conmel; Diprofarn; Gifaril; Lisador; Metamizol; Metamizole; Metamizole Sodium; Metamizole Sodium Salt; Metapyrin; Methamizole Sodium; Methampyrone; Methylmelubrin; Metilon; Narone; Sulpin; Sulpyrin; Sulpyrine. Grades: Highly Purified. CAS No. 68-89-3. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
Eicosatetraynoic Acid Quick inquiry Where to buy Suppliers range | ETYA is a nonspecific and cell permeable inhibitor of cyclooxygenases and lipoxygenases. ETYA inhibits phospholipase A2 (PLA2), cytochrome P-450, cyclooxygenase, 5-lipoxygenase, 12-lipoxygenase, and 15-lipoxygenase in whole cells. Synonyms: ETYA; 5,8,11,14-eicosatetraynoic acid; Octadehydroarachidonic acid. Grades: ≥98%. CAS No. 1191-85-1. Molecular formula: C20H24O2. Mole weight: 296.4. | |
Epoprostenol Sodium Quick inquiry Where to buy Suppliers range | Epoprostenol Sodium is the sodium salt form of epoprostenol, which is a synthetic prostacyclin. It has vasodilatory and anticoagulant activity. It is a short-lived product of the cyclooxygenase pathway in vascular endothelial cells. It prevents the formation of platelet plugs and is an effective vasodilator. It is a potent inhibitor of platelet aggregation by antagonizing thromboxane A2 and stimulating platelet adenylyl cyclase. It directly simulates prostaglandin receptors in arterial vascular smooth muscle, thereby causing vasodilatation. lt is also used for the treatment of pulmonary hypertension. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. It is vasoprotective, protecting arterial walls from injury-induced lesions and cytoprotective in the liver and gastrointestinal tract. It was developed by GlaxoSmithKline and has been listed. Uses: Epoprostenol sodium has vasodilatory and anticoagulant activity. it prevents the formation of platelet plugs and is an effective vasodilator. lt is also used for the treatment of pulmonary hypertension. Synonyms: Prostacyclin Sodium Salt; (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-Dihydroxy-prosta-5,13-dien-1-oic Acid Sodium Salt; Flolan. Grades: >99 %. CAS No. 61849-14-7. Molecular formula: C20H31O5Na. Mole weight: 374.45. | |
Etodolac Acyl Glucuronide Quick inquiry Where to buy Suppliers range | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1-(1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetate) b-D-glucopyranuronic acid; Etodolac glucuronide. Grades: > 95%. CAS No. 79541-43-8. Molecular formula: C23H29NO9. Mole weight: 463.48. | |
Etodolac Impurity B Quick inquiry Where to buy Suppliers range | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 8-Methyl Etodolac; 1-Ethyl-1,3,4,9-tetrahydro-8-methylpyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 41340-19-6. Molecular formula: C16H19NO3. Mole weight: 273.33. | |
Etodolac Impurity C Quick inquiry Where to buy Suppliers range | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 2-(8-ethyl-1-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid. Grades: > 95%. Molecular formula: C16H19NO3. Mole weight: 273.33. | |
Etodolac Impurity I Quick inquiry Where to buy Suppliers range | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 3-(7-ethyl-1H-indol-2-yl)-3-(7-ethyl-3-(2-hydroxyethyl)-1H-indol-2-yl)pentanoic acid. Grades: > 95%. Molecular formula: C27H32N2O3. Mole weight: 432.57. | |
Etodolac Impurity K Quick inquiry Where to buy Suppliers range | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester. Grades: > 95%. CAS No. 122188-02-7. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
Etodolac Impurity L Quick inquiry Where to buy Suppliers range | An impurity of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 3-(7-ethyl-3-(2-hydroxyethyl)-1H-indol-2-yl)pent-3-enoic acid. Grades: > 95%. Molecular formula: C17H21NO3. Mole weight: 287.36. | |
GYY-4137 Morpholine salt Quick inquiry Where to buy Suppliers range | GYY-4137 Morpholine salt is a novel water-soluble and slow releasing Hydrogen sulfide(H2S) donor. It protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats. It inhibits the inflammatory response by suppressing the activation of nuclear factor-kappa B and mitogen-activated protein kinases in Coxsackie virus B3-infected rat cardiomyocytes. It exhibits potent anti-cancer activity. It exhibits vasodilator and antihypertensive activity in rats, in either the acute or chronic hypertension models. It does not influence vascular smooth muscle cell viability in culture. It also protects against endotoxic shock in rats, inhibiting tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production and reducing NF-κB activation, iNOS and cyclooxygenase-2 expression, and NO and prostaglandin E2 generation. Uses: Gyy-4137 morpholine salt inhibits the inflammatory response. it exhibits potent anti-cancer activity. it exhibits vasodilator and antihypertensive activity. Synonyms: GYY4137; GYY-4137; GYY 4137; GYY 4137 morpholine salt; ZYJ1122; ZYJ 1122; ZYJ-1122. GYY4137 Morpholine salt;(4-Methoxyphenyl)morpholino-phosphinodithioic acid compound with morpholine;ZYJ1122 morpholine salt;ZYJ-1122 morpholine salt. Grades: ≥95%. CAS No. 106740-09-4. Molecular formula: C15H25N2O3PS2. Mole weight: 376.47. | |
Heneicosapentaenoic acid Quick inquiry Where to buy Suppliers range | Heneicosapentaenoic acid (HPA) is a 21:5 ω-3 fatty acid found in the green alga B. pennata and in fish oils. HPA is incorporated into phospholipids and into triacylglycerol in cell culture and inhibits the conversion of linolenic acid to arachidonic acid (AA) in hepatoma cells. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and for 5-lipoxygenase. Synonyms: HPA; (all-Z)-6,9,12,15,18-heneicosapentaenoic acid; (6Z,9Z,12Z,15Z,18Z)-6,9,12,15,18-henicosapentaenoic acid. Grades: ≥95%. CAS No. 24257-10-1. Molecular formula: C21H32O2. Mole weight: 316.5. | |
Heneicosapentaenoic acid methyl ester Quick inquiry Where to buy Suppliers range | Heneicosapentaenoic acid methyl ester is a derivative of heneicosapentaenoic acid (HPA), a 21:5 ω-3 fatty acid found in the green alga B. pennata and in fish oils. HPA is incorporated into phospholipids and into triacylglycerol in cell culture and inhibits the conversion of linolenic acid to arachidonic acid (AA) in hepatoma cells. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and for 5-lipoxygenase. Synonyms: HPA methyl ester; Methyl 6,9,12,15,18-heneicosapentaenoate; (all-Z)-6,9,12,15,18-heneicosapentaenoic acid methyl ester; (6Z,9Z,12Z,15Z,18Z)-6,9,12,15,18-henicosapentaenoic acid methyl ester. Grades: ≥98%. CAS No. 65919-53-1. Molecular formula: C22H34O2. Mole weight: 330.5. | |
Indomethacin (1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid) Quick inquiry Where to buy Suppliers range | Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD. Group: Biochemicals. Alternative Names: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
Indomethacin, 2'-Trifluoromethyl (Indomethacin, 2'-Trifluoromethyl, Indomethacin, 2-CF3, CF3-Indomethacin, CF3-INDO) Quick inquiry Where to buy Suppliers range | A cell-permeable, bioavailable 2-trifluoromethyl analog of Indomethacin that acts as a highly potent, time-dependent inhibitor of cyclooxygenase -2 (COX-2; IC50=267 and 388nM for mouse and human COX-2, respectively) and its several mutant forms. Does not affect COX-1 activity even at high concentrations (IC50 >100uM). Interacts with human COX-2 with much greater affinity than indomethacin (KI = 1.5 vs 13uM) and blocks COX-2 dependent arachidonic acid oxygenation (IC50 = 150nM in 1483 human head and neck squamous cell carcinoma cells). Further, minimizes swelling in carrageenan-induced rat paw edema model (EC50 = 1.7mg/kg, p.o.) with no gastrointestinal bleeding at higher doses (10mg/kg). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Indoprofen Quick inquiry Where to buy Suppliers range | Indoprofen, a non-steroidal anti-inflammatory drug, is a cyclooxygenase inhibitor and used for the treatment of pain and inflammation and spinal muscular atrophies. Uses: A non-steroidal anti-inflammatory agent. Synonyms: Indoprofen; Flosint; Isindone; K 4277; K-4277; K4277; Reumofene; 2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]propanoic acid;INDOPROFEN;ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID; 1-oxo-2- (p- ( (alpha-methyl) carboxymethyl) phenyl) isoindoline; 2- (4- (1-carboxyethyl) phenyl) -1-isoindolinone; 2- (p- (1-oxo-2-isoindolinyl) pheny. CAS No. 31842-01-0. Molecular formula: C17H15NO3. Mole weight: 281.31. | |
KB3022 Quick inquiry Where to buy Suppliers range | A cyclooxygenase (COX) inhibitor. Synonyms: ethyl 2-[2-[4,5-bis(4-methoxyphenyl)-1,3-thiazol-2-yl]pyrrol-1-yl]acetate; 1H-Pyrrole-1-acetic acid, 2-(4,5-bis(4-methoxyphenyl)-2-thiazolyl)-, ethyl ester; ethyl 2-(4,5-bis(4-methoxyphenyl)thiazol-2-yl)pyrrol-1-ylacetate; KB 3022; KB-3022; KBT-3022. CAS No. 101001-34-7. Molecular formula: C25H24N2O4S. Mole weight: 448.53. | |
Ketoprofen EP Impurity K Quick inquiry Where to buy Suppliers range | Ketoprofen EP Impurity K is an impurity of Ketoprofen, which is a cyclooxygenase inhibitor used as a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties. Synonyms: mixture of (2RS)-2-[3-(2,3,4-trimethylbenzoyl)phenyl]-propanoic acid and (2RS)-2-[3-(3,4,5-trimethylbenzoyl)-phenyl]propanoic acid; rac-Trimethyl Ketoprofen (Mixture of (2',3',4') and (3',4',5') Isomers). Grades: ≥95%. Molecular formula: C19H20O3. Mole weight: 296.37. | |
Ketoprofen EP Impurity L Quick inquiry Where to buy Suppliers range | Ketoprofen EP Impurity L is an impurity of Ketoprofen, which is a cyclooxygenase inhibitor used as a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties. Synonyms: (2RS)-2-[3-(2,4,5-trimethylbenzoyl)phenyl]propanoic acid; Benzeneacetic acid, α-methyl-3-(2,4,5-trimethylbenzoyl)-; α-Methyl-3-(2,4,5-trimethylbenzoyl)benzeneacetic acid; rac-2',4',5'-Trimethyl Ketoprofen; (+/-)-2-(3-(2,4,5-Trimethylbenzoyl)phenyl)propanoic acid. Grades: ≥95%. CAS No. 1797984-80-5. Molecular formula: C19H20O3. Mole weight: 296.37. | |
Licofelone Quick inquiry Where to buy Suppliers range | Dual inhibitor of cyclooxygenase and 5-lipoxygenase. Anti-inflammatory. Group: Biochemicals. Alternative Names: 6-(4-Chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-acetic Acid; ML-3000. Grades: Highly Purified. CAS No. 156897-06-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg. Molecular Formula: C??H??ClNO?, Molecular Weight: 379.88. US Biological Life Sciences. | Worldwide |
Loxoprofen Quick inquiry Where to buy Suppliers range | Loxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. It is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic Acid; 2-[4-[(2-Oxocyclopentan-1-yl)methyl]phenyl]propionic Acid; 2-[4-[ (2-Oxocyclopentyl) methyl]phenyl]propionic Acid. Grades: >98%. CAS No. 68767-14-6. Molecular formula: C15H18O3. Mole weight: 246.3. | |
Loxoprofen Sodium Quick inquiry Where to buy Suppliers range | A non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. It becomes active after metabolism in the body and inhibits the activation of cyclooxygenase. Group: Biochemicals. Alternative Names: α -Methyl-4-[ (2-oxocyclopentyl) methyl]benzeneacetic Acid Sodium Salt; CS 600; Loxonin; Sodium 2- [4- [ (2-Oxocyclopentyl) methyl] phenyl] propionate; Sodium Loxoprofen. Grades: Highly Purified. CAS No. 80382-23-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Lumiracoxib Quick inquiry Where to buy Suppliers range | Selective cyclooxygenase-2-(COX-2) inhibitor. Anti-inflammatory. Group: Biochemicals. Alternative Names: 2-[(2-Chloro-6-fluorophenyl)amino]-5-methylbenzeneacetic Acid; 2-[2-(2-Chloro-6-fluorophenylamino)-5-methylphenyl]acetic Acid; CGS 35189; COX 189; Prexige. Grades: Highly Purified. CAS No. 220991-20-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Nafazatrom Quick inquiry Where to buy Suppliers range | Nafazatrom is a pyrazolinone derivative. It increases endogenous prostacyclin (PGI2) and has potential antimetastatic activities. It is used an antithrombotic drug that increases PGI2 levels. It inhibits the key prostaglandin catabolic enzyme, 15-hydroxyprostaglandin dehydrogenase, which prolongs the biological half-life of PGI2 and prevents intravascular coagulation. It also serves as a reducing cofactor with the hydroperoxidase moiety of cyclooxygenase and accelerates the conversion of arachidonic acid into precursors of PGI2. It is a lipoxygenase inhibitor, reduces stimulated Prolactin secretion. It also reduces the incidence of accompanying arrhythmias in myocardial injuries. Uses: Nafazatrom is used an antithrombotic drug. Synonyms: 2,4-Dihydro-5-methyl-2-[2-(2-naphthalenyloxy)ethyl]-3H-pyrazol-3-one; Bay-g-6575; BAY g 6575; 3-methyl-1-(2-(naphthalen-2-yloxy)ethyl)-1H-pyrazol-5(4H)-one. Grades: 98%. CAS No. 59040-30-1. Molecular formula: C16H16N2O2. Mole weight: 268.32. | |
NBD-Binding Peptide II, Cell Permeable (CTP-NBD, NEMO-Binding Domain Binding Peptide II, Cell-Permeable, CTP-NBD) Quick inquiry Where to buy Suppliers range | A cell-permeable cytoplasmic transduction peptide (CTP; YGRRARRRARR) fused to the NEMO binding domain peptide (NBD; TALDWSWLQTE) that acts as a potent inhibitor of TNFa-stimulated NF-kB activity (IC50~50uM in HCT116 cells). Acts by interfering with the formation of active IKK complex and thereby prevents lkBa phosphorylation and its subsequent proteasomal degradation. Also blocks LPS-mediated increase in inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) activities. Colon-targeted capsules containing CTP-NBD are shown to reduce 2, 4, 6-trinitro Benzene sulfonic acid (TNBS)-induced colitis in rodent models (4.5mg/kg/,p.o.) in vivo and diminish activities of myeloperoxidase and several inflammatory mediators. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
NCX 466 Quick inquiry Where to buy Suppliers range | NCX 466 is a cyclooxygenase inhibiting nitric oxide donors (CINODs). NCX 466 shows higher efficacy in reducing levels of profibrotic cytokine transforming growth factor-β and oxidative stress in a mouse model of bleomycin-induced lung fibrosis camparing to naproxen. Synonyms: (αS)-6-Methoxy-α-methyl-2-naphthaleneacetic acid (5S)-5,6-bis(nitrooxy)hexyl ester. Grades: ≥98% by HPLC. CAS No. 1262956-64-8. Molecular formula: C20H24N2O9. Mole weight: 436.41. | |
NCX 466 ((aS)-6-Methoxy-a-methyl-2-naphthalene acetic acid (5S)-5,6-bis(nitrooxy)hexyl ester) Quick inquiry Where to buy Suppliers range | Cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor (CINOD). Inhibits COX-1 and COX-2 while releasing NO. Demonstrates higher efficacy than naproxen, its congener drug, in reducing levels of profibrotic cytokine transforming growth factor-beta and oxidative stress in a mouse model of bleomycin-induced lung fibrosis. Orally available. Group: Biochemicals. Grades: Highly Purified. CAS No. 1262956-64-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Niflumic Acid Quick inquiry Where to buy Suppliers range | Cyclooxygenase-2 (COX-2) inhibitor; GPR35 agonist. Nonsteroidal anti-inflammatory drug (NSAID); selectively inhibits COX-2. Also activates human TRPA1 inducibly expressed in HEK293 cells; displays agonist activity at GPR35. Group: Biochemicals. Alternative Names: 2-[[3- (Trifluoromethyl) phenyl]amino]-3-pyridinecarboxylic Acid; 2-[3- (Trifluoromethyl) anilino]nicotinic Acid; Actol; Actol (analgesic); Donalgin; Flogovital; Forenol; Landruma; Nifluminic Acid; Nifluril; UP 83. Grades: Highly Purified. CAS No. 4394-00-7. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C13H9F3N2O2, Molecular Weight: 282.22. US Biological Life Sciences. | Worldwide |
Niflumic Acid-d5 (Major) Quick inquiry Where to buy Suppliers range | Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor. Group: Biochemicals. Alternative Names: 2-[[3- (Trifluoromethyl) phenyl]amino]-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
N-Methyl Etodolac Quick inquiry Where to buy Suppliers range | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1,8-Diethyl-1,3,4,9-tetrahydro-9-methylpyrano[3,4]indole-1-acetic Acid. Grades: > 95%. CAS No. 849630-94-0. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
Nordihydroguaiaretic acid Quick inquiry Where to buy Suppliers range | NDGA (Nordihydroguaiaretic acid), also known as masoprocol, is a naturally occurring antioxidant dicatechol originally derived from the creosote bush Larrea divaricatta with antipromoter, anti-inflammatory, and antineoplastic activities. NDGA directly inhibits activation of two receptor tyrosine kinases (RTKs), the insulin-like growth factor receptor (IGF-1R) and the c-erbB2/HER2/neu receptor, resulting in decreased proliferation of susceptible tumor cell populations. This agent may induce apoptosis in susceptible tumor cell populations as a result of disruption of the actin cytoskeleton in association with the activation of stress activated protein kinases (SAPKs). In addition, NDGA inhibits arachidonic acid 5-lipoxygenase (5LOX), resulting in diminished synthesis of inflammatory mediators such as prostaglandins and leukotrines; it may prevent leukocyte infiltration into tissues and the release of reactive oxygen species and, at higher concentrations, may also inhibit cyclooxygenase. Synonyms: 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol. Grades: > 98 %. CAS No. 500-38-9. Molecular formula: C18H22O4. Mole weight: 302.36. | |
(R)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic Acid Quick inquiry Where to buy Suppliers range | An isomer of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Uses: The r-enantiomer of etodolac (e933090). anti-inflammatory; analgesic. Synonyms: 2-[(1R)-1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl]acetic acid; 2-[(1R)-1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl]acetic acid. Grades: > 95 %. CAS No. 87226-41-3. Molecular formula: C17H21NO3. Mole weight: 287.35. | |
rac-Etodolac Quick inquiry Where to buy Suppliers range | rac-Etodolac is a non-selective inhibitor of COX. Uses: Cyclooxygenase 2 inhibitors. Synonyms: Etodolac, AY 24,236, AY 24236, AY-24,236, AY-24236, AY24,236, AY24236, 1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic Acid; (RS)-Etodolic Acid; (+/-)-Etodolac; AY 24236; Eccoxolac; Edolan; Etodine; Etodolic Acid; Etogesic; Lodin XL; Lodine; NIH 9918; NSC 282126; Napilac; Ramodar; Tedolan; Ultradol; Zedolac. Grades: > 95%. CAS No. 41340-25-4. Molecular formula: C17H21NO3. Mole weight: 287.35. | |
Radicicol (Monorden) Quick inquiry Where to buy Suppliers range | Radicicol is a resorcylic acid lactone produced by several fungal species that exhibits broad spectrum antifungal and antitumor activity. Radicicol has been the subject of extensive investigation and been shown to inhibit protein tyrosine kinase, induce the differentiation of HL-60 cells into macrophages, block cell cycle at G1 and G2, suppress NIH 3T3 cell transformation by diverse oncogenes such as src, ras and mos and also suppress the expression of mitogen-inducible cyclooxygenase-2. As a cell differentiation modulator, radicicol has anti-angiogenic activity in vivo, inhibiting the proliferation of plasminogen activator production by vascular endothelial cells. Group: Biochemicals. Alternative Names: Monorden. Grades: Highly Purified. CAS No. 12772-57-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Rebamipide Quick inquiry Where to buy Suppliers range | Rebamipide has been shown to enhance mucosal defense by scavenging free radicals, and temporarily activating genes encoding cyclooxygenase-2. Uses: Enzyme inhibitors. Synonyms: Proamipide; Mucosta; OPC-12759; 2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid; 2-(4-chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid; NSC-758955; 2-[(4-chlorobenzoyl)amino]-3-(2-hydroxyquinolin-4-yl)propanoic acid. Grades: >98%. CAS No. 90098-04-7. Molecular formula: C19H15ClN2O4. Mole weight: 370.79. | |
Salicylic acid Quick inquiry Where to buy Suppliers range | Salicylic acid is a natural product extract from Willow bark, well known as an antiinflammatory inhibitor of cyclooxygenase activity. It is widely used in organic synthesis and functions as a plant hormone and is known for its ability to ease aches and pains and reduce fevers. It is derived from the metabolism of salicin. It and its derivatives are used as constituents of some rubefacient products. Uses: Anti-infective agents; antifungal agents; keratolytic agents. Synonyms: 2-hydroxybenzoic acid. Grades: > 98 %. CAS No. 69-72-7. Molecular formula: C7H6O3. Mole weight: 138.12. | |
Salsalate-d4 Quick inquiry Where to buy Suppliers range | Nonacetylated salicylate. Non-steroidal anti-inflammatory drug (NSAID). Reduces pain and inflammation caused by conditions such as rheumatoid arthritis, osteoarthritis and related rheumatic conditions. Prostaglandin synthesis inhibitor in vivo. Inactivates cyclooxygenase-1 (COX-1) and -2 (COX-2). IKKbeta/NF-kappaB inhibitor (at significantly higher concentrations than required for COX inhibition). Used to target inflammation in the treatment of insulin resistance, type 2 diabetes, or rheumatic pain. Group: Biochemicals. Alternative Names: 2-Hydroxybenzoic Acid 2-Carboxyphenyl Ester-d4; Salicylic Acid Salicylate-d4; 2-Hydroxybenzoic Acid 2-Carboxyphenyl Ester-d4; Diacesal-d4; Diplosal-d4; Disalcid-d4; Disalgesic-d4; Disalicylic-d4 Acid; Disalyl-d4; Mono-Gesic-d4; NSC 49171-d4; Nobacid-d4; Salflex-d4; Salical-d4; Salicyl Salicylate-d4; Salicyloxysalicylic Acid-d4; Salicyloylsalicylic-d4 Acid; Salicylsalicylic-d4 Acid; Salina-d4; Salsalate-d4; Salysal-d4; Sasapirin-d4; Sasapyrine-d4; Sasapyrinum-d4; o-Salicylsalicylic-d4 Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
Salsalate (NSC 49171) Quick inquiry Where to buy Suppliers range | Nonacetylated salicylate. Non-steroidal anti-inflammatory drug (NSAID). Reduces pain and inflammation caused by conditions such as rheumatoid arthritis, osteoarthritis and related rheumatic conditions. Prostaglandin synthesis inhibitor in vivo. Inactivates cyclooxygenase-1 (COX-1) and -2 (COX-2). IKKbeta/NF-kappaB inhibitor (at significantly higher concentrations than required for COX inhibition). Used to target inflammation in the treatment of insulin resistance, type 2 diabetes, or rheumatic pain.Salsalate reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes. Reduces blood glucose, triglyceride, free fatty acid and C-reactive protein concentrations, improves glucose utilization and increases circulating insulin and adiponectin concentrations in obese adults at risk for the development of type 2 diabetes as well as for patients with type 2 diabetes. Dimeric prodrug comprising two esterified salicylate moieties. It is advantageous over sodium salicylate because it is insoluble at the acid pH of the stomach and passes suspended but undissolved into the small intestine, sparing the gastric mucosa direct contact. Group: Biochemicals. Alternative Names: Salicylsalicylic acid, NSC 49171, BRN 2590908, 2-Hydroxy-2-carboxyphenyl ester-benzoic acid. Grades: Highly Purified. CAS No. 552-94-3. Pack Sizes: 1g, 5g, 10g, 25g, 50g. Molecular Formula: C??H??O?, Molecular Weight: 258.23. US Biological Life Sciences. | Worldwide |
(S)-Etodolac Quick inquiry Where to buy Suppliers range | An isomer of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: (1S)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 87249-11-4. Molecular formula: C17H21NO3. Mole weight: 287.36. |