Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| 15-keto-17-phenyl trinor prostaglandin F2α | 15-keto-17-phenyl-13,14-dihydro trinor PGF2α isopropyl ester is a miotic in the normal cat eye, causing an 8 mm reduction in pupillary diameter at 5 μg/eye. Synonyms: 15-keto-17-phenyl trinor PGF2α; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxo-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid. Grades: ≥98%. CAS No. 949564-89-0. Molecular formula: C23H30O5. Mole weight: 386.5. |  |
| 2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester | 2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester is an intermediate used in the synthesis of rac-3-Oxo Atorvastatin Sodium Salt (O847150), which is a byproduct impurity of Atorvastatin Calcium (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 947262-20-6. Pack Sizes: 500ug, 1mg. Molecular Formula: C37H41FN2O5, Molecular Weight: 612.73. US Biological Life Sciences. |  Worldwide |
| (3R,5S)-Atorvastatin Acetonide tert-Butyl Ester | (3R,5S)-Atorvastatin Acetonide tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl 1,3-Dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl (4R,6S)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate. CAS No. 947249-30-1. Molecular formula: C40H47FN2O5. Mole weight: 654.81. | |
| (3R,5S)-Fluvastatin sodium | (3R,5S)-Fluvastatin ((3R,5S)-XU 62-320) sodium is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (3R,5S)-XU 62-320. CAS No. 94061-80-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14664F. |  |
| (3R,5S) Fluvastatin Sodium ((3R,5S)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt) | A synthetic HMG-CoA reductase inhibitor. Antilipemic. Group: Biochemicals. Alternative Names: (3R,5S)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt. Grades: Highly Purified. CAS No. 94061-80-0. Pack Sizes: 1mg. Molecular Formula: C24H25FNNaO4, Molecular Weight: 433.45. US Biological Life Sciences. | Worldwide |
| Acebilustat | Acebilustat, formerly known as ZK322, is an oral anti-inflammatory designed to reduce the production of leukotriene B4 (LTB4). Synonyms: 4-(((1S,4S)-5-(4-(4-(oxazol-2-yl)phenoxy)benzyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)methyl)benzoic acid; ZK322; ZK-322; ZK 322; CTX-4430; EP-501; CTX4430; EP501; CTX 4430; EP 501; Acebilustat, CAS#943764-99-6. CAS No. 943764-99-6. Molecular formula: C29H27N3O4. Mole weight: 481.55. | |
| Allisartan isoproxil | Allisartan isoproxil is a nonpeptide angiotensin II receptor blocker (ARB) precursor drug that is used to treat hypertension and reduce the risk of heart disease. Allisartan isoproxil alleviates diabetic cardiomyopathy by attenuating diabetes - induced oxidative stress and inflammation through the SIRT1/Nrf2/NF - κB signalling pathway. Synonyms: 1H-Imidazole-5-carboxylic acid, 2-butyl-4-chloro-1-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, (((1-methylethoxy)carbonyl)oxy)methyl ester; SB16810; SB-16810; SB 16810. CAS No. 947331-05-7. Molecular formula: C27H29ClN6O5. Mole weight: 553.02. | |
| BGC-945 | BGC 945 is a cyclopenta[g]quinazoline-based, thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)-overexpressing tumors. BGC 945 has low affinity for the widely expressed reduced-folate carrier (RFC). BGC 945 selectively inhibits thymidylate synthase in α-FR-overexpressing tumors and should cause minimal toxicity to humans at therapeutic doses. Synonyms: Idetrexed; ONX-0801; N-[4-[2-Propynyl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-1H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-glutamic acid; N-[4-[2-Propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-glutamic acid; (R) -2- ( (S) -4-carboxy-4- (4- ( ( (S) -2- (hydroxymethyl) -4-oxo-4, 6, 7, 8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl) (prop-2-yn-1-yl) amino) benzamido) butanamido) pentanedioic acid. Grades: ≥95%. CAS No. 501332-69-0. Molecular formula: C32H33N5O10. Mole weight: 647.63. | |
| Carbomer 940 | Acrylic acid is a colorless liquid with a distinctive acrid odor. Flash point 130°F. Boiling point 286°F. Freezing point 53°F. Corrosive to metals and tissue. Prolonged exposure to fire or heat can cause polymerization. If polymerization takes place in a closed container, violent rupture may occur. The inhibitor (usually hydroquinone) greatly reduces the tendency to polymerize.;Acrylic acid, [waste] appears as a colorless liquid with a distinctive acrid odor. Combustible. Flash point 130°F. Boiling point 286°F. Freezing point 121°F. Corrosive to metals and tissue. May polymerize under prolonged exposure to fire or heat. If polymerization occurs in a container violent rupture may occur. Generally shipped with an inhibitor such as hydroquinone to prevent polymerization.; Liquid; Liquid; COLOURLESS LIQUID WITH PUNGENT ODOUR.;Colorless liquid or solid (below 55°F) with a distinctive, acrid odor.;Colorless liquid or solid (below 55°F) with a distinctive, acrid odor. [Note: Shipped with an inhibitor (e.g., hydroquinone) since it readily polymerizes.]. Group: Heterocyclic organic compound. Alternative Names: Acritamer 940;Lanopol 940;Acrypol 940;Phytogel base;Carbopol 940. CAS No. 76050-42-5. Molecular formula: C3H4O2;CH2=CHCOOH;C3H4O2. Mole weight: 72.06g/mol. IUPACName: prop-2-enoic acid. Canonical SMILES: C=CC(=O)O. Density: 1.0497 at 68 °F (USCG, 1999);1.05 (NIOSH, 2016);1.0511 g/cu cm at 20 °C;1.54 g/mL at 25 °C/4 °C;Relative |  |
| Carbomer 940 | Acrylic acid is a colorless liquid with a distinctive acrid odor. Flash point 130°F. Boiling point 286°F. Freezing point 53°F. Corrosive to metals and tissue. Prolonged exposure to fire or heat can cause polymerization. If polymerization takes place in a closed container, violent rupture may occur. The inhibitor (usually hydroquinone) greatly reduces the tendency to polymerize.;Acrylic acid, [waste] appears as a colorless liquid with a distinctive acrid odor. Combustible. Flash point 130°F. Boiling point 286°F. Freezing point 121°F. Corrosive to metals and tissue. May polymerize under prolonged exposure to fire or heat. If polymerization occurs in a container violent rupture may occur. Generally shipped with an inhibitor such as hydroquinone to prevent polymerization.; Liquid; Liquid; COLOURLESS LIQUID WITH PUNGENT ODOUR.;Colorless liquid or solid (below 55°F) with a distinctive, acrid odor.;Colorless liquid or solid (below 55°F) with a distinctive, acrid odor. [Note: Shipped with an inhibitor (e.g., hydroquinone) since it readily polymerizes.]. Group: Polymers. Alternative Names: Acritamer 940; Lanopol 940; Acrypol 940; Phytogel base; Carbopol 940. CAS No. 76050-42-5. Product ID: prop-2-enoic acid. Molecular formula: 72.06g/mol. Mole weight: C3H4O2;CH2=CHCOOH;C3H4O2. C=CC(=O)O. InChI=1S/C3H4O2/c1-2-3(4)5/h2H, 1H2, (H, 4, 5). NIXOWILDQLNWCW-UHFFFAOYSA-N. |  |
| Carbomer 940 | Carbomer 940. Synonyms: Acritamer; acrylic acid polymer; Carbopol; carboxy polymethylene, polyacrylic acid; carboxyvinyl polymer; Pemulen; Ultrez. CAS No. 9003-1-4. Product ID: PE-0637. Molecular formula: (C3H4O2)n. Category: Suspending Agents; Thickener. Product Keywords: Excipients for Liquid Dosage Form; Suspending Agents; PE-0637; Carbomer 940; Suspending Agents; Thickener; (C3H4O2)n; 9003-01-4. UNII: 4Q93RCW27E. Chemical Name: Cross-linked polyacrylic resin. Grade: Pharmceutical Excipients. Administration route: Topical; Ophthalmic; Transdermal. Dosage Form: Oral suspensions and tablets, ophthalmic preparations, rectal preparations and topical preparations. Stability and Storage Conditions: Carbomer is a stable and hygroscopic substance that does not affect its thickening when heated at 104°C for 2 hours. However, exposure to excessive temperatures can reduce discoloration and stability. It is completely decomposed by heating at 260°C for 30 minutes. Dry powdery carbomer does not grow mildew. In contrast, microbes grow well in preservative-free aqueous dispersions. Therefore, preservatives such as 0.1%(W/V) of chlorocresol, 0.18% (W/V) of hydroxyphenylene methyl, 0.02%(W/V) of hydroxyphenylene propyl, or 0.1%(W/V) of thiomersal should be added. The addition of certain bacteriostatic agents, such as benzalammonium chloride or sodium benzoate, at high concentrations (0.1%W/V) caused turbidity and decreased viscosity |  |
| fatty-acyl-CoA synthase | The enzyme from yeasts (Ascomycota and Basidiomycota) is a multi-functional protein complex composed of two subunits. One subunit catalyses the reactions EC 1.1.1.100, 3-oxoacyl-[acyl-carrier-protein] reductase and EC 2.3.1.41, 3-oxoacyl-[acyl-carrier-protein] synthase, while the other subunit catalyses the reactions of EC 2.3.1.38, [acyl-carrier-protein] S-acetyltransferase, EC 2.3.1.39, [acyl-carrier-protein] S-malonyltransferase, EC 4.2.1.59, 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase, EC 1.3.1.10, enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific) and EC 1.1.1.279, (R)-3-hydroxyacid ester dehydrogenase. The enzyme differs from the animal enzyme (EC 2.3.1.85) in that the enoyl reductase domain requires FMN as a cofactor, and the ultimate product is an acyl-CoA (usually palmitoyl-CoA) instead of a free fatty acid. Group: Enzymes. Synonyms: yeast fatty acid synthase; FAS1 (gene name); FAS2 (gene name). Enzyme Commission Number: EC 2.3.1.86. CAS No. 94219-29-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2267; fatty-acyl-CoA synthase; EC 2.3.1.86; 94219-29-1; yeast fatty acid synthase; FAS1 (gene name); FAS2 (gene name). Cat No: EXWM-2267. |  |
| Fmoc-γ-azidohomoalanine | A useful tool for the synthesis of branched, side-chain modified, cyclic peptides and peptide tools for click chemistry by Fmoc SPPS. The side-chain azido group is completely stable to piperidine and TFA, but can be readily converted to an amine on the solid phase or in solution by reduction with thiols or phosphines. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-γ-azidohomoalanine. CAS No. 942518-20-9. Molecular formula: C19H18N4O4. Mole weight: 366.37. Purity: Peak Area by HPLC ≥95%. Catalog: ACM942518209. | |
| Pitavastatin Impurity 2 | (3R,5S)-5-(6-Cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (βR,δS)-6-Cyclopropyl-10-fluoro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid; Pitavastatin Impurity 2 (PP-2). Grades: 94%. CAS No. 1187966-93-3. Molecular formula: C25H22FNO4. Mole weight: 419.44. | |
| Rose Bengal, 90%, indicator | Rose Bengal, 90%, indicator. Group: Xanthene dyes. Alternative Names: Acid Red 94; Rosa bengala sodica (131 I) [INN-Spanish]; C20H2Cl4I4Na2O5; disodium 4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-3-oxospiro[2-benzo[b]furan-1,9'-xanthene]-3',6'-diolate; C.I. 45440; Food Red Color No. 105, sodium salt; FT-0621857; Xantryl; Rose bengal disodium salt; R105 sodium. CAS No. 632-69-9. Product ID: disodium; 4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-3-oxospiro[2-benzofuran-1,9'-xanthene]-3',6'-diolate. Molecular formula: 1017.628g/mol. Mole weight: C20H2Cl4I4Na2O5. C1=C2C (=C (C (=C1I)[O-])I)OC3=C (C (=C (C=C3C24C5=C (C (=C (C (=C5Cl)Cl)Cl)Cl)C (=O)O4)I)[O-])I. [Na+]. [Na+]. InChI=1S/C20H4Cl4I4O5. 2Na/c21-9-7-8 (10 (22)12 (24)11 (9)23)20 (33-19 (7)31)3-1-5 (25)15 (29)13 (27)17 (3)32-18-4 (20)2-6 (26)16 (30)14 (18)28; ; /h1-2, 29-30H; ; /q; 2*+1/p-2. KCQREHTWEUECQT-UHFFFAOYSA-L. | |
| Shepherdin | Shepherdin 79-87 is amino acids 79 to 87 fragment of Shepherdin. Shepherdin makes extensive contacts with the ATP pocket of Hsp90, destabilizes its client proteins, and induces massive death of tumor cells by apoptotic and nonapoptotic mechanisms. Conversely, shepherdin does not reduce the viability of normal cells nor affect colony formation of purified hematopoietic progenitors. Systemic administration of shepherdin in vivo is well tolerated, and inhibits human tumor growth in mice without toxicity. Synonyms: NSC-741765; L-Lysyl-L-histidyl-L-seryl-L-serylglycyl-L-cysteinyl-L-alanyl-L-phenylalanyl-3-methyl-L-valine. Grades: >98%. CAS No. 861224-28-4. Molecular formula: C41H64N12O12S. Mole weight: 949.09. | |
| TB500 acetate | TB500 acetate, a synthetic version of the active region of thymosin β4, has been reported to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition, and reduce inflammation. Synonyms: TB 500 acetate; Frag17-23 acetate; N-acetyl-L-leucyl-L-lysyl-L-lysyl-L-threonyl-L-alpha-glutamyl-L-threonyl-L-glutamine acetic acid; Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C40H72N10O16. Mole weight: 949.06. | |
| Tigapotide | PCK3145 is a synthetic 15-mer peptide corresponding to amino acids 31-45 of the 94-amino acid isoform of human prostate secretory protein (PSP-94) with potential anti-metastasis and anti-angiogenesis activities. PSP-94-derived peptide PCK3145 may inhibit the secretion of the metastasis-related protein matrix metalloproteinase-9 (MMP-9) and its potential binding to its cell surface receptor CD44; may interfere with the vascular endothelial growth factor (VEGF) signaling pathway, resulting in an anti-angiogenesis effect; and may reduce the levels of parathyroid hormone-related protein (PTHrP), decreasing plasma calcium levels. PSP-94, one of three predominant proteins found in seminal fluid, may be down-regulated in prostate cancer, representing a potential survival mechanism for prostate cancer cells. MMP-9 is implicated in the invasion and metastasis of cancer. PTHrP may be expressed by various tumor cell types, resulting in the hypercalcemia of malignancy. Synonyms: PCK3145. Chemical name: L-Threonine, L-glutamyl-L-tryptophyl-L-glutaminyl-L-threonyl-L--aspartyl-L-asparaginyl-S-[(acetylamino)methyl]-L-cysteinyl-L-glutamyl-L-threonyl-S-[(acetylamino)methyl]-L-cysteinyl-L-threonyl-S-[(acetylamino)methyl]-L-cysteinyl-L-t. CAS No. 848084-83-3. Molecular formula: C82H119N21O34S3. Mole weight: 2039.15. | |
| WWL 113 | WWL 113 is a carboxylesterase Ces3 and Ces1f inhibitor (IC50 = ~100 nM) with minimal activity against a panel of other serine hydrolases. WWL 113 was indicated ability to reduce weight gain in diet-induced obese mice and potentiate glucose tolerance in diabetic mice. It significantly reduces basal lipolysis in adipocytes. Synonyms: WWL113; WWL-113; WWL 113; 4'-[[[Methyl[[3- (4-pyridinyl) phenyl]methyl]amino]carbonyl]oxy]-[1, 1'-biphenyl]-4-carboxylic acid ethyl ester. Grades: ≥99% by HPLC. CAS No. 947669-86-5. Molecular formula: C29H26N2O4. Mole weight: 466.53. | |
| ZP 1609 | ZP 1609, a small modified dipeptide, has been identified as a potent and selective second generation gap junction modifier with oral bioavailability. It is a pharmalogical agent with a favorable clinical safety profile and potential antiarrhythmic efficacy, which is confirmed in phase I clinical trials. It is used for the treatment of atrial fibrillation. It improves conduction and reduces atrial fibrillation or flutter in the canine sterile pericarditis model. It prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs. It showed consistent efficacy on measures of conduction and AF/AFL inducibility in the canine sterile pericarditis model. It was developed by Zealand Pharma and was termination in Clinical phase II. Uses: Zp 1609 is a pharmalogical agent with a favorable clinical safety profile and potential antiarrhythmic efficacy. it is used for the treatment of atrial fibrillation. Synonyms: GAP-134; GAP 134; GAP134; ZP-1609; ZP1609; ZP 1609; (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid;Danegaptide. Grades: >98 %. CAS No. 943134-39-2. Molecular formula: C14H17N3O4. Mole weight: 291.30. | |
Our database is helping our users find suppliers everyday.
