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D-Alaninamide,d-phenylalanyl-L-phenylalanyl-L-tyrosyl-D-tryptophyl-L-Lysyl-L-valyl-l-phenylalanyl-3-(2-naphthalenyl)-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BIM 23056;D-PHE-PHE-TYR-D-TRP-LYS-VAL-PHE-D-NAL-NH2;D-Phe-Phe-Tyr-D-Trp-Lys-VaL-Phe-D-Nal-NH2 trifluoroacetate salt;M.W. 1232.49 C71H81N11O9. Product Category: Heterocyclic Organic Compound. Appearance: White lyophilised solid. CAS No. 150155-61-6. Molecular formula: C71H81N11O9. Mole weight: 1232.49. Purity: 0.96. IUPACName: (2S)-6-amino-N-[(2S)-1-[[(2S)-1-[[(2R)-1-amino-3-naphthalen-2-yl-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-hydroxyp. Canonical SMILES: CC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC2=CC3=CC=CC=C3C=C2)C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CC4=CNC5=CC=CC=C54)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC8=CC=CC=C8)N. Product ID: ACM150155616. Alfa Chemistry ISO 9001:2015 Certified.
D-Alaninamide,N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-n6-[bis(ethylamino)methylene]-D-Lysyl-L-leucyl-n6-[bis(ethylamino)methylene]-l-lys. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Antagon;N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide;Orgalutran;RS 26306. Product Category: Heterocyclic Organic Compound. CAS No. 124904-93-4. Molecular formula: C80H113ClN18O13. Mole weight: 1570.319. Purity: 0.96. IUPACName: 1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[(2-acetamido-3-naphthalen-2-ylpropanoyl)amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-6-[bis(ethylami. Density: 1.31 g/cm³. Product ID: ACM124904934. Alfa Chemistry ISO 9001:2015 Certified.
L-Alaninamide,N-(ethoxycarbonyl)-L-alanyl-L-tyrosyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: ETHOXYCARBONYL-ALA-TYR-VAL-ALA-ASP-ALDEHYDE (PSEUDO ACID). Product Category: Heterocyclic Organic Compound. CAS No. 160534-05-4. Molecular formula: C27H39N5O10. Mole weight: 593.63. Purity: 0.96. IUPACName: (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(ethoxycarbonylamino)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-oxobutanoicacid. Canonical SMILES: CCOC(=O)NC(C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(CC(=O)O)C=O. Product ID: ACM160534054. Alfa Chemistry ISO 9001:2015 Certified.
N~1~-(2-ETHYLPHENYL)-BETA-ALANINAMIDE 95%
N~1~-(2-ETHYLPHENYL)-BETA-ALANINAMIDE 95%. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-AMINO-N-(2-ETHYLPHENYL)PROPANAMIDE, 938515-55-0, Ambcb4028300, CTK7E7180, MolPort-003-789-493, AKOS000104182, MCULE-2445215600, N~1~-(2-ethylphenyl)-beta-alaninamide, AJ-59182, AK121502, Y-5369. Product Category: Heterocyclic Organic Compound. CAS No. 938515-55-0. Molecular formula: C11H16N2O. Mole weight: 192.2604. Purity: 0.96. IUPACName: 3-amino-N-(2-ethylphenyl)propanamide. Product ID: ACM938515550. Alfa Chemistry ISO 9001:2015 Certified.
An intermediate for the synthesis of some HIV protease inhibitors. Group: Biochemicals. Alternative Names: N-[(1S)-2-(Methoxymethylamino)-2-oxo-1-(phenyl-d5-methyl)ethyl]carbamic Acid 1,1-Dimethylethyl Ester; tert-Butyl [(1S)-1-(benzyl-d5)-2-[methoxy(methyl)amino]-2-oxoethyl]carbamate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
N-[ (Phenylmethoxy) carbonyl]-L-valyl-N-[3-fluoro-1- (2-methoxy-2-oxoethyl) -2-oxopropyl]-L-alaninamide. Group: Biochemicals. Alternative Names: Z-VAD-FMK; Benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone. Grades: Highly Purified. CAS No. 634911-81-2. Pack Sizes: 1 mg. Molecular Formula: C22H30FN3O7, Molecular Weight: 467.49. US Biological Life Sciences.
Worldwide
Thiostrepton (Bryamycin, Thiactin, Alaninamide, Antibiotic X 146, Antibiotic A 8506, Antibiotic 6761-31)
Thiostrepton is a macrocyclic antibiotic incorporating thiazoles and other atypical amino acids. Patented in 1961, thiostrepton has been used as an antibiotic and acts by binding to ribosomes to prevent the binding of the EF-G elongation factor and GTP to the 50S riobsomal subunit. Thiostrepton is an inducer of tipA, a gene that controls the bacterial transcription regulators, TipAL and TipAS, members of the MerR proteins that are central regulators in multidrug resistance. Closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor-FoxM1. Group: Biochemicals. Alternative Names: Bryamycin, Thiactin, Alaninamide, Antibiotic X 146, Antibiotic A 8506, Antibiotic 6761-31. Grades: Highly Purified. CAS No. 1393-48-2. Pack Sizes: 5mg. US Biological Life Sciences.
An impurity of safinamide, which is a selective monoamine oxidase B inhibitor reducing degradation of dopamine. Synonyms: Safinamide Impurity 4; (R)-N2-{4-[(3-fluorobenzyl)oxy]benzyl}alaninamide. Grade: ≥ 98%. CAS No. 174756-44-6. Molecular formula: C17H19FN2O2. Mole weight: 302.349.
3-(Methylamino)propanamide
3-(Methylamino)propanamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(Methylamino)propanamide, 3-(Methylamino)propionamide, 4874-17-3, N~3~-methyl-beta-alaninamide, ACMC-20anih, N-Methyl-beta-alanamide, Ambcb4029061, CTK6I5558, MolPort-008-643-551, BBL023425, STL069432, AKOS005289623, AG-A-53914, AK121223, KB-85684. Product Category: Heterocyclic Organic Compound. CAS No. 4874-17-3. Molecular formula: C4H10N2O. Mole weight: 102.14. Purity: 0.96. IUPACName: 3-(methylamino)propanamide. Canonical SMILES: CNCCC(=O)N. Product ID: ACM4874173. Alfa Chemistry ISO 9001:2015 Certified.
A-893
A-893 is an inhibitor of SMYD2, which is a lysine methyltransferase. The co-crystal structure reveals the origin of enhanced potency, and effective inhibition of p53K370 methylation in a lung carcinoma (A549) cell line. Synonyms: A893; A 893; (R)-N-cyclohexyl-3-((3,4-dichlorophenethyl)amino)-N-(2-((2-hydroxy-2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethyl)amino)ethyl)propanamide; Propanamide, N-cyclohexyl-3-[[2-(3,4-dichlorophenyl)ethyl]amino]-N-[2-[[(2R)-2-(3,4-dihydro-3-oxo-2H-1,4-benzoxazin-8-yl)-2-hydroxyethyl]amino]ethyl]-; N-Cyclohexyl-N3-[2-(3,4-dichlorophenyl)ethyl]-N-(2-{[(2R)-2-hydroxy-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-8-yl)ethyl]amino}ethyl)-β-alaninamide. Grade: ≥98%. CAS No. 1868232-32-9. Molecular formula: C29H38Cl2N4O4. Mole weight: 577.54.
AAF-CMK trifluoroacetate salt
AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome function, and reversibly inhibits Cln2 (TPPI). Synonyms: N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase Inhibitor II; L-Alaninamide,L-alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-. Grade: ≥95%. CAS No. 184901-82-4. Molecular formula: C18H23ClF3N3O5. Mole weight: 453.84.
Abaloparatide acetate
Abaloparatide acetate, an effective and selective activator of the PTHR1 signaling pathway, is an analog of parathyroid hormone-related protein (PTHrP) used for the treatment of osteoporosis. Synonyms: H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-Aib-Lys-Leu-His-Thr-Ala-NH2.CH3CO2H; L-alanyl-L-valyl-L-seryl-L-alpha-glutamyl-L-histidyl-L-glutaminyl-L-leucyl-L-leucyl-L-histidyl-L-alpha-aspartyl-L-lysyl-glycyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-alpha-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-lysyl-L-leucyl-L-leucyl-alpha-methyl-alanyl-L-lysyl-L-leucyl-L-histidyl-L-threonyl-L-alaninamide acetic acid. Grade: ≥95%. Molecular formula: C176H304N56O51. Mole weight: 4020.71.
Abaloparatide TFA
Abaloparatide TFA is an analog of parathyroid hormone-related protein (PTHrP) used for the treatment of osteoporosis. Synonyms: H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-Aib-Lys-Leu-His-Thr-Ala-NH2.TFA; L-alanyl-L-valyl-L-seryl-L-alpha-glutamyl-L-histidyl-L-glutaminyl-L-leucyl-L-leucyl-L-histidyl-L-alpha-aspartyl-L-lysyl-glycyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-alpha-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-lysyl-L-leucyl-L-leucyl-alpha-methyl-alanyl-L-lysyl-L-leucyl-L-histidyl-L-threonyl-L-alaninamide trifluoroacetic acid; BIM 44058 trifluoroacetate; Eladynos trifluoroacetate. Grade: ≥95%. Molecular formula: C176H301N56F3O51. Mole weight: 4074.61.
Acetyl Pepstatin
Acetyl Pepstatin is a high affinity HIV-1 protease inhibitor and aspartic protease inhibitor. It inhibits HIV-1 protease with Ki value of 20 nM at pH 4.7 and HIV-2 protease with Ki value of 5 nM at pH 4.7. It is used as an antiviral agent. Synonyms: Ac-Pepstatin; [1S-[1R*,2R*,4[R*[R*(R*)]]]]-1-(2-Methylpropyl)-4-oxobutyl]-N-acetyl-L-valyl-N-[4-[[2-[[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]amino]-1-methyl-2-oxoethyl]amino]-2-hydroxy-L-valinamide; Pepsin Inhibitor S-PI-D (8CI); N-Acetyl-L-valyl-L-valyl-(3S,4S)-4-amino-3-hydroxy-6- methylheptanoyl-N-[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]-L-alaninamide; Pepsidin C; S-PI; (4S,7S,8S,10S,19S)-8-carbamoyl-11,19-dihydroxy-10,18-diisobutyl-4-isopropyl-7,15-dimethyl-2,5,13,16-tetraoxo-3,9,14,17-tetraazahenicosan-21-oic acid. Grade: >98%. CAS No. 11076-29-2. Molecular formula: C31H57N5O9. Mole weight: 643.81.
Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-NH2
Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-NH2 is a synthetically derived peptide used in cosmetic formulations. It is known for its ability to influence muscle contraction, which can help in reducing the appearance of fine lines and wrinkles. This peptide is often marketed as a more accessible and less invasive alternative to Botox, offering anti-aging benefits by promoting skin firmness and elasticity. Synonyms: N-Acetyl-L-α-glutamyl-L-α-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-arginyl-L-alaninamide; Acetyl-EEMQRRA-NH2; Ac-EEMQRRA-NH2; Acetyl Heptapeptide-4 amide; Acetyl Heptapeptide-4-NH2. Grade: ≥95%. CAS No. 868844-72-8. Molecular formula: C37H65N15O13S. Mole weight: 960.07.
Ac-Val-Asp-Val-Ala-Asp-aldehyde (pseudo acid)
Ac-VDVAD-CHO is an inhibitor of caspase-2, -3, and -7 (Kis = 3.5, 1, and 7.5 nM, respectively). Synonyms: Ac-VDVAD-CHO; N-acetyl-L-valyl-L-alpha-aspartyl-L-valyl-L-alanyl-L-aspart-1-al; N-Acetyl-L-valyl-L-α-aspartyl-L-valyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-alaninamide; L-Alaninamide, N-acetyl-L-valyl-L-α-aspartyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-; Caspase-2 Inhibitor (Aldehyde). Grade: ≥95%. CAS No. 194022-51-0. Molecular formula: C23H37N5O10. Mole weight: 543.57.
Ac-YVAD-CHO
Ac-YVAD-CHO is a selective inhibitor of interleukin-1β converting enzyme (ICE; Caspase-1). Uses: Cysteine proteinase inhibitors. Synonyms: Acetyl-tyrosyl-valyl-alanyl-aspartal; Ac-Tyr-Val-Ala-Asp-H; N-acetyl-Tyr-Val-Ala-Asp-aldehyde; (S)-N-Acetyl-L-tyrosyl-L-valyl-N-(2-carboxy-1-formylethyl)-L-alaninamide. Grade: ≥98%. CAS No. 143313-51-3. Molecular formula: C23H32N4O8. Mole weight: 492.52.
(Ala11.22.28)-VIP (human, mouse, rat)
(Ala11.22.28)-VIP (human, mouse, rat), a highly selective human VPAC1 receptor agonist, shows a 1000-fold higher efficiency in stimulating adenylate cyclase activity from VPAC1 than VPAC2 receptors. It is a valid pharmacological tool for characterizing VPAC1 receptor-mediated events. Synonyms: (Ala11.22.28)-Aviptadil; H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Ala-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Ala-Leu-Asn-Ser-Ile-Leu-Ala-NH2; L-histidyl-L-seryl-L-alpha-aspartyl-L-alanyl-L-valyl-L-phenylalanyl-L-threonyl-L-alpha-aspartyl-L-asparagyl-L-tyrosyl-L-alanyl-L-arginyl-L-leucyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-valyl-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-asparagyl-L-seryl-L-isoleucyl-L-leucyl-L-alaninamide. Grade: ≥95% by HPLC. CAS No. 291524-04-4. Molecular formula: C139H231N43O39S. Mole weight: 3160.65.
Alafosfalin
Alafosfalin is an inhibitor of cell wall biosynthesis. Alaphosphin is used as a selection agent for isolation of Salmonella and as a dipeptide mimetic antibacterial agent. Synonyms: Alaphosphin; n-[(1r)-1-phosphonoethyl]-l-alaninamide; (1R)-1-(L-Alanylamino)ethylphosphonic acid; Alafosfalino; L-Alanyl-L-1-aminoethylphosphonic Acid; Ro 03-7008. CAS No. 60668-24-8. Molecular formula: C5H13N2O4P. Mole weight: 196.14.
Alanine-nh2 acetate salt
Alanine-nh2 acetate salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-ALANINE AMIDE ACETATE; H-Ala-NH2; H-Ala-NH2(L-Alaninamide); H-ALA-NH2 ACOH; L-ALANINE AMIDE ACETATE SALT; H-ALA-NH2 ACETATE SALT. Product Category: Heterocyclic Organic Compound. CAS No. 119864-22-1. Molecular formula: C3H8N2O. Mole weight: 88.11. Purity: 0.96. IUPACName: acetic acid;2-aminopropanamide. Canonical SMILES: CC(C(=O)N)N.CC(=O)O. Product ID: ACM119864221. Alfa Chemistry ISO 9001:2015 Certified.
Alanylbactobolin
It is produced by the strain of Pseudomonas sp. BMG 13-A7. It has anti-gram-positive bacteria, negative bacteria and tumor activity. Synonyms: Bactobolin B; L-Alaninamide, L-alanyl-N-(3-(dichloromethyl)-3,4,4a,5,6,7-hexahydro-5,6,8-trihydroxy-3-methyl-1-oxo-1H-2-benzopyran-4-yl)-, (3S-(3-alpha,4-alpha,4a-beta,5-beta,6-alpha))-; DTXSID80995581; 5-Amino-2-{[3-(dichloromethyl)-1,5,6-trihydroxy-3-methyl-8-oxo-4,4a,5,6,7,8-hexahydro-3H-2-benzopyran-4-yl]amino}-4-oxohexanimidic acid. CAS No. 74141-68-7. Molecular formula: C17H25N3O7Cl2. Mole weight: 454.30.
Alatrofloxacin Mesylate
Alatrofloxacin Mesylate is the mesylate salt form of the fluoroquinolone derivative Alatrofloxacin, a type II DNA topoisomerase inhibitor that has been developed as an antibacterial agent. Synonyms: L-Alaninamide, L-alanyl-N-[(1α,5α,6α)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-, methanesulfonate (1:1); L-Alaninamide, L-alanyl-N-[(1α,5α,6α)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-, monomethanesulfonate; L-Alaninamide, L-alanyl-N-[3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-, (1α,5α,6α)-, monomethanesulfonate; Adrenochrome monoaminoguanidine mesilate; CP 116517; CP 116517-27; Trovan IV; Turvel IV; 7-((1R,5S,6s)-6-((S)-2-((S)-2-aminopropanamido)propanamido)-3-azabicyclo[3.1.0]hexan-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid compound with methanesulfonic acid (1:1). Grade: ≥95%. CAS No. 146961-77-5. Molecular formula: C27H29F3N6O8S. Mole weight: 654.61.
The parental prodrug of Trovafloxacin, on phagocytic, anti-inflammatory and immunomodulation events of human THP-1 monocytes. Group: Biochemicals. Alternative Names: L-Alanyl-N-[(1α, 5α, 6α)-3-[6-carboxy-8-(2, 4-difluorophenyl)-3-fluoro-5, 8-dihydro-5-oxo-1, 8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-L-alaninamide Methanesulfonate; L-Alanyl-N-[(1α, 5α, 6α)-3-[6-carboxy-8-(2, 4-difluorophenyl)-3-fluoro-5, 8-dihydro-5-oxo-1, 8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-L-alaninamide Mesylate. Grades: Highly Purified. CAS No. 146961-77-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Alitame
Alitame is a dipeptide amide derivative of aspartic acid used as an artificial sweetener. Alitame is about ten times sweeter than Aspartame with a half life about twice as long. Group: Biochemicals. Alternative Names: L-α-Aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide; (S)-3-Amino-4-oxo-4-(((R)-1-oxo-1-((2,2,4,4-tetramethylthietan-3-yl)amino)propan-2-yl)amino)butanoic acid; CP 54802. Grades: Highly Purified. CAS No. 80863-62-3. Pack Sizes: 1g. US Biological Life Sciences.
Alloc-Val-Ala-PAB-OH is a peptide linker with a terminal Alloc protecting group. The peptide chain can act as a cleavable linker in drug design, such as in antibody drug conjugates (ADC). Synonyms: Allyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate; N-(Allyloxycarbonyl)-L-valyl-[4-(hydroxymethyl)phenyl]-L-alaninamide; N-(Allyloxycarbonyl)-L-valyl-[4-(hydroxymethyl)phenyl]-L-alaninamide. CAS No. 1343407-91-9. Molecular formula: C19H27N3O5. Mole weight: 377.43.
α-Synuclein Binding Peptide
α-Synuclein Binding Peptide is a 10-residue peptide antagonist, corresponding to the sequence of the α-synuclein binding peptide, and effectively inhibits α-synuclein aggregation and related toxicity at 1:1 stoichiometry. Synonyms: L-Alaninamide, N2-acetyl-L-lysyl-L-α-aspartylglycyl-L-isoleucyl-L-valyl-L-asparaginylglycyl-L-valyl-L-lysyl-; Ac-Lys-Asp-Gly-Ile-Val-Asn-Gly-Val-Lys-Ala-NH2; α-syn Binding Peptide. Grade: ≥95%. CAS No. 2243207-00-1. Molecular formula: C45H80N14O14. Mole weight: 1041.20.
Antide Acetate
Antide is a GnRH and LH-RH antagonist that displays potent anti-ovulatory and weak histamine release activity. Synonyms: N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-N6-(3-pyridinylcarbonyl)-L-lysyl-N6-(3-pyridinylcarbonyl)-D-lysyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-D-alaninamide, monoacetate. CAS No. 625092-10-6. Molecular formula: C84H112ClN17O16. Mole weight: 1651.30.
(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat)
(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) is an effective antagonist against pTH-stimulated cAMP production in ROS cells and shows no partial agonism effect. Synonyms: (Asn10,Leu11,D-Trp12)-Hypercalcemia of Malignancy Factor (7-34) amide (human, mouse, rat); H-Leu-Leu-His-Asn-Leu-D-Trp-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2; L-Leucyl-L-leucyl-L-histidyl-L-asparaginyl-L-leucyl-D-tryptophyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-α-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-histidyl-L-histidyl-L-leucyl-L-isoleucyl-L-alanyl-L-α-glutamyl-L-isoleucyl-L-histidyl-L-threonyl-L-alaninamide; (Asn10,Leu11,D-Trp12)-pTHrP (7-34) amide. Grade: ≥95%. CAS No. 129622-68-0. Molecular formula: C162H254N50O36. Mole weight: 3478.06.
AtuFECT01
AtuFect01 is part of the lipid system AtuPLEX and shows more effective siRNA binding activity and delivery to vascular endothelial cells. Synonyms: β-Alaninamide, L-arginyl-2-amino-N-hexadecyl-N-(9Z)-9-octadecenyl-, trihydrochloride, (2S)-; β-Alaninamide, L-arginyl-2-amino-N-hexadecyl-N-(9Z)-9-octadecen-1-yl-, hydrochloride (1:3), (2S)-; (S)-2-amino-N-((S)-2-amino-3-(hexadecyl((Z)-octadec-9-en-1-yl)amino)-3-oxopropyl)-5-guanidinopentanamide trihydrochloride. Grade: ≥95%. CAS No. 869094-19-9. Molecular formula: C43H87N7O2.3HCl. Mole weight: 843.58.
[betaAla-D-Cit]-Cetrorelix
An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-beta-Ala-DCit-Leu-Arg-Pro-DAla-NH2; [β-Ala-D-Cit]-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-β-Ala-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-beta-alanyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; betaAla-DCit-Cetrorelix; betaAla-D-Cit-Cetrorelix. Grade: ≥95%. Molecular formula: C73H97ClN18O15. Mole weight: 1502.14.
[betaAla-Leu]-Cetrorelix
An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-beta-Ala-Leu-Arg-Pro-DAla-NH2; [β-Ala-Leu]-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-β-Ala-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-beta-alanyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; betaAla-Leu-Cetrorelix. Grade: ≥95%. Molecular formula: C73H97ClN18O15. Mole weight: 1502.14.
BIM 23056 acetate is a potent and surmountable human recombinant somatostatin receptor antagonist (Ki = 142, >1000, 10.8, 16.6 and 5.7 nM for human cloned sst1-5 receptors, respectively). It acts as an antagonist on SRIF14-induced [35S]-GTPγS binding at sst3 and sst5 receptors (PKB = 6.33 and 5.84, respectively). Synonyms: H-D-Phe-Phe-Tyr-D-Trp-Lys-Val-Phe-D-2Nal-NH2.CH3CO2H; D-phenylalanyl-L-phenylalanyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-phenylalanyl-3-(2-naphthyl)-D-alaninamide acetic acid. Grade: ≥95%. CAS No. 2763584-06-9. Molecular formula: C73H85N11O11. Mole weight: 1292.52.
Boc-Ala-NH2
Boc-Ala-NH2 (CAS# 85642-13-3) is a useful research chemical. Synonyms: N-α-(t-Butoxycarbonyl)-L-alaninamide; (S)-tert-Butyl (1-amino-1-oxopropan-2-yl)carbamate; (S)-Boc-alaninamide. CAS No. 85642-13-3. Molecular formula: C8H16N2O3. Mole weight: 188.23.
Boc-Trp-Met-Asp-Phe-NH2
Boc-Trp-Met-Asp-Phe-NH2 refers to Tetragastrin, which has been modified with a BOC (tert-Butyloxycarbonyl) group. The BOC group is a commonly used amino protecting group in organic synthesis, especially in peptide synthesis. Tetragastrin itself is the C-terminal tetrapeptide of gastrin, with the sequence H-Trp-Met-Asp-Phe-NH2. Tetragastrin stimulates gastric secretion and acts as a Cholecystokinin (CCK-4) receptor agonist. It is known for its gastric mucosal protective effects and is used to improve symptoms of hypochlorhydria or gastric atony, as well as in the treatment of atrophic gastritis. Synonyms: BOC-Tetragastrin; 4-7-Cholecystokinin-7 (swine), N-[(1,1-dimethylethoxy)carbonyl]-; Alaninamide, N-carboxy-L-tryptophyl-L-methionyl-L-aspartylphenyl-, N-tert-butyl ester, L-; N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide; (tert-Butoxycarbonyl)tetragastrin; Boc-CCK-4; Boc-WMDF-NH2; N-tert-Butoxycarbonyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide. Grade: ≥95%. CAS No. 5235-21-2. Molecular formula: C34H44N6O8S. Mole weight: 696.81.
Cetrorelix
Cetrorelix is a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Uses: Fertility agents. Synonyms: Ac-D-2-Nal-4-chloro-D-Phe-β-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-; SB-075. Grade: >98%. CAS No. 120287-85-6. Molecular formula: C70H92ClN17O14. Mole weight: 1431.04.
Cetrorelix Acetate
Cetrorelix Acetate. Group: Biochemicals. Alternative Names: N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide Acetate; N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide Acetate; Cetrotid; Cetrotide; D 20761; NS 75A; SB 075 acetate. Grades: Highly Purified. CAS No. 145672-81-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cetrorelix Acetate
Cetrorelix Acetate is the acetate salt of cetrorelix, which is a potent and synthetic peptide antagonist of gonadotropin-releasing hormone (GnRH) receptor antagonist with IC50 value of 1.21 nM. It binds to radioligand murine LTK- cells with Kd value of 0.2 nM. It inhibits the activation of hGnRHR and a downstream luciferase reporter gene in murine LTK- cells by the GnRHR agonist [D-Trp6]GnRH. It suppresses production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland. It prevents ovulation during in vitro fertilization. It causes prepubertal reduction in bone density, bone strength and bone modeling. It was used as a therapeutic agent for the treatment of blood cancers such as multiple myeloma (MM). It is also used to treat hormone-sensitive cancers of the breast and prostate. It also has antidepressant and anxiolytic activity in vivo. Uses: Fertility agents, female. Synonyms: D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (1:x); D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (salt); Cetrotid; C. Grade: >98%. CAS No. 145672-81-7. Molecular formula: C70H92ClN17O14.xC2H4O2. Mole weight: 1431.06 (free base)
Cetrorelix diacetate
Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist. Under the trade name Cetrotide, It is indicated for the inhibition of premature LH surges in women undergoing controlled ovarian stimulation. Synonyms: D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, diacetate (salt); Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2.CH3CO2H; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate salt. Grade: ≥95%. CAS No. 130143-01-0. Molecular formula: C74H100ClN17O18. Mole weight: 1551.16.
Cetrorelix Dimer
Cetrorelix Dimer is an impurity of Cetrorelix, which is a gonadotropin-releasing hormone antagonist used in the treatment of prostate and breast cancers. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-Arg-Pro-DAla-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-Arg-Pro-DAla-NH2; Dimer Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alanyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide. Grade: ≥95%. Molecular formula: C138H179Cl2N33O27. Mole weight: 2803.05.
Cetrorelix trifluoroacetate
Cetrorelix trifluoroacetate is the salt of Cetrorelix, which is a gonadotropin-releasing hormone antagonist used in the treatment of prostate and breast cancers. Uses: Fertility agents, female. Synonyms: D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, 2,2,2-trifluoroacetate (1:1); D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, mono(trifluoroacetate) (salt); SB 75; SB 75 (antitumor agent); Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2.TFA; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide trifluoroacetic acid. Grade: 95%. CAS No. 130289-71-3. Molecular formula: C70H92ClN17O14.C2HF3O2. Mole weight: 1545.06.
Chitinovorin B
Chitinovorin B is produced by the strain of Flavobacerium chitinovorum PB-5016 and PB-5246. Synonyms: L-Alaninamide, L-alanyl-N-(4-((7-((5-amino-5-carboxy-1-oxopentyl)amino)-2-carboxy-7-(formylamino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methoxy)-1-(3-((aminoiminomethyl)amino)propyl)-2-hydroxy-4-oxobutyl)-, (6R-(3(1S*,2R*),6alpha,7beta(R*)))-. Grade: >98%. CAS No. 95722-76-2. Molecular formula: C29H46N10O12S. Mole weight: 758.80.
CI 992
CI 992 is a renin inhibitor originated by Pfizer. Preclinical trials for Hypertension in USA was discontinued in 1994. Uses: Hypertension. Synonyms: CI 992; CI992; CI-992. N-(4-morpholinylsulfonyl)-L-phenylalanyl-3-(2-amino-4-thiazolyl)-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-alaninamide; [1S-(1R*,2S*,3R*)]- N-(4-morpholinylsulfonyl)-L-phenylalanyl-3-(2-amino-4-thiazolyl)-N-[1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-alaninamide; PD 134672; PD134672; PD-134672. Grade: 98%. CAS No. 135704-06-2. Molecular formula: C33H52N6O7S2. Mole weight: 708.94.
Compound E
Compound E is a cell-permeable inhibitor of γ-secretase (GSI), which is a multifunctional transmembrane protein complex enzymatically catalyzing the cleavage of single-pass transmembrane proteins. Compound E can inhibit Notch processing (IC50 = 2.2 nM in SupT1 cells) and β-ammyloid production in cell culture (IC50 = 0.3 nM). Synonyms: γ-Secretase Inhibitor; Gamma-Secretase Inhibitor XXI; (S,S)- 2-[2-(3,5-Difluorophenyl)-acetylamino]-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionamide; (2S)-2-{[(3,5-Difluorophenyl)acetyl]amino}-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide; N2-[(3,5-difluorophenyl)acetyl]-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-L-alaninamide. Grade: 98%. CAS No. 209986-17-4. Molecular formula: C27H24F2N4O3. Mole weight: 490.5.
CRF, bovine
CRF, bovine is an effective agonist of CRF (Corticotropin-releasing factor) receptor. Synonyms: Corticotropin Releasing Factor bovine; H-Ser-Gln-Glu-D-Pro-D-Pro-Ile-Ser-Leu-Asp-Leu-aThr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-DL-Met-Thr-Lys-D-Ala-D-Asp-D-Gln-D-Leu-D-Ala-D-Gln-D-Gln-D-Ala-D-His-D-Asn-D-Asn-D-Arg-D-Lys-D-Leu-D-Leu-D-Asp-aIle-D-Ala-NH2; L-seryl-L-glutaminyl-L-alpha-glutamyl-D-prolyl-D-prolyl-L-isoleucyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-leucyl-L-allothreonyl-L-phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-alpha-glutamyl-L-valyl-L-leucyl-L-alpha-glutamyl-DL-methionyl-L-threonyl-L-lysyl-D-alanyl-D-alpha-aspartyl-D-glutaminyl-D-leucyl-D-alanyl-D-glutaminyl-D-glutaminyl-D-alanyl-D-histidyl-D-asparagyl-D-asparagyl-D-arginyl-D-lysyl-D-leucyl-D-leucyl-D-alpha-aspartyl-L-alloisoleucyl-D-alaninamide. Grade: 95%. CAS No. 92307-52-3. Molecular formula: C206H340N60O63S. Mole weight: 4697.33.
[D-Arg8]-Cetrorelix
[D-Arg8]-Cetrorelix is a derivative of Cetrorelix, a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-DArg-Pro-DAla-NH2; D-Arg8-Cetrorelix; (D-Arg8)-Cetrorelix; D-Arg(8)-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-D-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-D-arginyl-L-prolyl-D-alaninamide. Grade: ≥95%. CAS No. 3031679-78-1. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06.
[D-Cit(Ac)6]Cetrorelix
[D-Cit(Ac)6]Cetrorelix is a derivative of Cetrorelix, a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit(Ac)-Leu-Arg-Pro-DAla-NH2; DCit(Ac)-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit(Ac)-Leu-Arg-Pro-D-Ala-NH2; D-Cit(Ac)6-Cetrorelix; D-Cit(Ac)-Cetrorelix; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-N-acetyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-[(acetylamino)carbonyl]-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide. Grade: ≥95%. CAS No. 1631741-33-7. Molecular formula: C72H94ClN17O15. Mole weight: 1473.07.
Degarelix acetate
Degarelix is a synthetic gonadotropin-releasing hormone receptor (GNRHR) antagonist. It decreases tumor volume of Dunning R3327H prostate tumor flank implants in rats when administered at a dose of 1 mg/kg per month. Formulations containing degarelix have been used in the treatment of advanced prostate cancer. Synonyms: Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Phe(4-S-dihydroorotamido)-D-Phe(4-ureido)-Leu-Lys(iPr)-Pro-D-Ala-NH2.CH3CO2H; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-4-((S)-dihydroorotamido)-L-phenylalanyl-4-ureido-D-phenylalanyl-L-leucyl-N6-isopropyl-L-lysyl-L-prolyl-D-alaninamide acetic acid; D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-L-phenylalanyl-4-[(aminocarbonyl)amino]-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-, acetate (1:1); FE 200486; Gonax. Grade: ≥98%. CAS No. 934016-19-0. Molecular formula: C82H103ClN18O16.C2H4O2. Mole weight: 1692.31.
[Des-Ac-D-2Nal]-Cetrorelix
An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-Arg-Pro-DAla-NH2; Des-Ac-D2NalCetrorelix; D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; 4-Chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; Des-Ac-D2Nal-Cetrorelix; [Des-Ac-D-2Nal]1-Cetrorelix. Grade: ≥95%. Molecular formula: C55H79ClN16O12. Mole weight: 1191.79.
Des-Acety-Cetrorelix
Des-Acety-Cetrorelix is an impurity of Cetrorelix, which is a gonadotropin-releasing hormone antagonist used in the treatment of prostate and breast cancers. Synonyms: D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Alanine amide; Cetrorelix Impurity-9; Des-Ac-Cetrorelix; 3-(2-Naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; (S)-N-((R)-1-amino-1-oxopropan-2-yl)-1-((2S,5S,8R,11S,14S,17R,20R,23R)-23-amino-20-(4-chlorobenzyl)-2-(3-((diaminomethylene)amino)propyl)-11-(4-hydroxybenzyl)-14-(hydroxymethyl)-5-isobutyl-24-(naphthalen-2-yl)-4,7,10,13,16,19,22-heptaoxo-17-(pyridin-3-ylmethyl)-8-(3-ureidopropyl)-3,6,9,12,15,18,21-heptaazatetracosanoyl)pyrrolidine-2-carboxamide; D-Alaninamide, 3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-. CAS No. 121081-09-2. Molecular formula: C68H90ClN17O13. Mole weight: 1389.02.
Di-Ser4-Cetrorelix
An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Ser-Tyr-DCit-Leu-Arg-Pro-DAla-NH2; [Di-Ser]4-Cetrorelix; [Di-Ser4]-Cetrorelix; Di-Ser(4)-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide. Grade: ≥95%. Molecular formula: C73H97ClN18O16. Mole weight: 1518.14.
D-Leu7-Cetrorelix
An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-DLeu-Arg-Pro-DAla-NH2; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-D-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-D-leucyl-L-arginyl-L-prolyl-D-alaninamide; [D-Leu]7-Cetrorelix; [D-Leu7]-Cetrorelix; D-Leu(7)-Cetrorelix. Grade: ≥95%. CAS No. 3031679-81-6. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06.
[D-Pro9]-Cetrorelix
[D-Pro9]-Cetrorelix is a derivative of Cetrorelix, a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-Arg-DPro-DAla-NH2; D-Pro9-Cetrorelix; [D-Pro]9-Cetrorelix; D-Pro(9)-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-D-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-D-prolyl-D-alaninamide. Grade: ≥95%. CAS No. 3031679-75-8. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06.
[D-Ser4]-Cetrorelix
[D-Ser4]-Cetrorelix is a derivative of Cetrorelix, a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Synonyms: D-Ser4-Cetrorelix; (D-Ser4)-Cetrorelix; D-Ser(4)-Cetrorelix; D-Ser-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-D-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; Ac-D2Nal-D4Cpa-D3Pal-DSer-Tyr-DCit-Leu-Arg-Pro-DAla-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-D-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide. Grade: ≥95%. CAS No. 3031679-89-4. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06.
D-Tyr5-Cetrorelix
An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-DTyr-DCit-Leu-Arg-Pro-DAla-NH2; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-D-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-D-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; [D-Tyr]5-Cetrorelix; [D-Tyr5]-Cetrorelix; D-Tyr(5)-Cetrorelix. Grade: ≥95%. CAS No. 3031679-86-1. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06.
Endo-3-D-Pal-Cetrorelix
Endo-3-D-Pal-Cetrorelix is an impurity of Cetrorelix, which is a gonadotropin-releasing hormone antagonist used in the treatment of prostate and breast cancers. Synonyms: Ac-D-2Nal-D-Phe(4-Cl)-D-3-Pal-D-3-Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide. Molecular formula: C78H100ClN19O15. Mole weight: 1579.23.
FE-999024
FE-999024, a dipeptide compound, has been found to be a kallikrein inhibitor that was once studied in pancreatitis by Ferring Pharmaceuticals. Synonyms: FE-999024; FE 999024; FE999024; CH-2856; CH2856; CH 2856; L-Alaninamide, 4-chloro-D-phenylalanyl-N-(3-((aminoiminomethyl)amino)propyl)-3-(1-naphthalenyl)-. Grade: 98%. CAS No. 168825-65-8. Molecular formula: C26H31ClN6O2. Mole weight: 495.02.
FK 888
FK 888 is a potent and selective tachykinin NK1 receptor antagonist (Ki = 0.69 nM) with 320-fold selectivity for human over rat NK1 receptors. It inhibits substance P-induced contraction of isolated guinea pig trachea (IC50 = 32 nM) and inhibits substance P-induced airway constriction in vivo following i.v. and oral administration. Synonyms: FK-888; FK 888; FK888. (4R)-4-Hydroxy-1-[(1-methyl-1H-indol-3-yl)carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-L-alaninamide; (2S,4R)-N-[(2S)-1-[benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-4-hydroxy-1-(1-methylindole-3-carbonyl)pyrrolidine-2-carboxamide. Grade: ≥98% by HPLC. CAS No. 138449-07-7. Molecular formula: C36H36N4O4. Mole weight: 588.69.
Fluorescein-6-carbonyl-Tyr-Val-Ala-DL-Asp(OMe)-fluoromethylketone is an inhibitor of caspase-1. Synonyms: 6-FAM-YVAD(OMe)-FMK; L-Alaninamide, N-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl)carbonyl]-L-tyrosyl-L-valyl-N-[1-(2-fluoroacetyl)-3-methoxy-3-oxopropyl]-; N-[(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-6-yl)carbonyl]-L-tyrosyl-L-valyl-N-(5-fluoro-1-methoxy-1,4-dioxo-3-pentanyl)-L-alaninamide. Grade: ≥90%. CAS No. 1926163-69-0. Molecular formula: C44H43FN4O13. Mole weight: 854.84.
Fluorogenic Human CMV Protease Substrate
Fluorogenic Human CMV Protease Substrate, the FRET substrate, is used to develop a fluorescence-based detection method for human cytomegalovirus proteinase. It specifically cleaves on the Ala-Ser bond, thereby removing the C-terminal peptide-Edans fragment from the proximity quenching effect of DABCYL groups. This represents the first fluorescence-based assay of the herpes virus protease and allows characterization of potential inhibitors. Synonyms: DABCYL-Arg-Gly-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-Ala-EDANS; N2-[4-[2-[4-(Dimethylamino)phenyl]diazenyl]benzoyl]-L-arginylglycyl-L-valyl-L-valyl-L-asparaginyl-L-alanyl-L-seryl-L-seryl-L-arginyl-L-leucyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-alaninamide. Grade: 95%. CAS No. 163265-38-1. Molecular formula: C73H109N23O18S. Mole weight: 1628.85.
Ganirelix
Ganirelix is a GnRH antagonist used primarily in assisted reproduction to control ovulation. It acts by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Synonyms: D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide; D 24598; Orgalutran; RS 26306; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-hArg(Et,Et)-Leu-hArg(Et,Et)-Pro-D-Ala-NH2. Grade: 95%. CAS No. 124904-93-4. Molecular formula: C80H113ClN18O13. Mole weight: 1570.32.
Ganirelix acetate
Ganirelix acetate. Group: Biochemicals. Alternative Names: N-Acetyl-3- (2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3- (3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis (ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis (ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide. Grades: Highly Purified. CAS No. 129311-55-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C84H121ClN18O17. US Biological Life Sciences.
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