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Alkynyl-modifier-C6-dT CEP is a renowned compound extensively utilized in the biomedical sector, serving as a pivotal chemical modification compound employed for labeling and detection purposes across diverse applications in compound research and disease analysis. Molecular formula: C48H58N5O9P. Mole weight: 879.98.
1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose
1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose is a specialized chemical often involved in studies related to cancer treatments. It's a key component in synthesizing innovative pharmaceuticals aimed at combating tumor growth and expansion. Synonyms: 1,2,3,4-Tetra-O-acetyl-6,7-dideoxy-L-galacto-hept-6-ynopyranose. CAS No. 935658-91-6. Molecular formula: C15H18O9. Mole weight: 342.30.
5-Alkynyl-L-fucose
5-Alkynyl-L-fucose is a remarkable compound harnessed for studying an array of cell adhesion, immune response and glycosylation-associated ailments. Its wide-ranging utilities span from unraveling intricate cellular processes to devising precision-focused cancer and immune disorder researchs. Synonyms: L-Altro-6.7-dideoxy-hept-6-ynose. CAS No. 1193251-61-4. Molecular formula: C7H10O5. Mole weight: 174.15.
2nd Generation Maruoka chiral phase transfer catalyst, for enantioselective alkylation of α-amino acid derivatives, that is easily recovered for recycle by extraction with fluorous solvent. Catalyst for asymmetric conjugate addition of α -substituted-α -cyanoacetates to α,β-unsaturated acetylenic esters. Phase transfer catalyzed enantioselective α-alkylation. Asymmetric amination of β-keto esters. Diastereo- and enantioselective conjugate addition of α-substituted nitroacetates to maleimides. Cyclization of β-alkynyl hydrazines. Group: Heterocyclic organic compound. Alternative Names: MFCD09264271; (S)-4,4-DIBUTYL-2,6-BIS(3,4,5-TRIFLUOROPHENYL)-4,5-DIHYDRO-3H-DINAPHTHO[7,6,1,2-CDE]AZEPINIUM BROMIDE; 887938-70-7; (S)-4,4-Dibutyl-2,6-bis(3,4,5-trifluorophenyl)-4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-e]azepin-4-ium bromide; (11bR)-(-)-4,4-Dibutyl-4,5-dihydro-2,6-bis(3,4,5-trifluorophenyl)-3H-dinaphth[2,1-c:1 inverted exclamation marka,2 inverted exclamation marka-e]azepinium bromide. CAS No. 851942-89-7. Molecular formula: C42H36BrF6N. Mole weight: 748.651g/mol. IUPACName: 13, 13-dibutyl-10, 16-bis(3, 4, 5-trifluorophenyl)-13-azoniapentacyclo[13.8.0.02, 11.03, 8.018, 23]tricosa-1(15), 2(11), 3, 5, 7, 9, 16, 18, 20, 22-decaene;bromide. Canonical SMILES: CCCC[N+]1 (CC2=C (C3=CC=CC=C3C=C2C4=
1,2,3,4,5,6-Hexaethynylbenzene
Alkynyl COFs Ligands. Alternative Names: Hexaethynylbenzene. CAS No. 100516-61-8. Molecular formula: C18H6. Mole weight: 222.24024. Appearance: Light green solid. Purity: 0.98. Catalog: ACM100516618.
1- (2, 4-Dihydroxy-5-isopropylphenyl) ethanone
1- (2, 4-Dihydroxy-5-isopropylphenyl) ethanone acts as a reagent in the synthesis of 3,5-disubstituted-4-alkynylisoxozales as HSP90 inhibitors against various human cancer cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 747414-17-1. Pack Sizes: 250mg, 500mg. Molecular Formula: C11H14O3, Molecular Weight: 194.23. US Biological Life Sciences.
Worldwide
1,2-Bis(4-ethynylphenyl)-1,2-diphenylethene
Alkynyl COFs Ligands. Alternative Names: 1-Ethynyl-4-[2-(4-ethynylphenyl)-1,2-diphenylethenyl]benzene. CAS No. 1240785-42-5. Molecular formula: C30H20. Mole weight: 380.47. Purity: 95%+. Catalog: ACM1240785425.
1,2-Bis((prop-2-yn-1-yloxy)methyl)benzene
Alkynyl COFs Ligands. Alternative Names: Benzene, 1,2-bis[(2-propynyloxy)methyl]-. CAS No. 126422-60-4. Molecular formula: C14H14O2. Mole weight: 214.25. Purity: 95%+. Catalog: ACM126422604.
17-Octadecynoic acid is a suicide inhibitor of LTB4 ω-oxidase. 17-ODYA can completely inhibit the bradykinin-dependent transport of sodium chloride in rat TALH cells at a concentration of 10 μM. Synonyms: Alkynyl Stearic Acid;17-Octadecynoic acid. Grades: ≥98% by HPLC. CAS No. 34450-18-5. Molecular formula: C18H32O2. Mole weight: 280.45.
1-Heptyne can be used for cycloisomerization of alkynyl imines and alkynylation of oxiranes. Group: Biochemicals. Grades: Highly Purified. CAS No. 628-71-7. Pack Sizes: 5g, 25g. Molecular Formula: C7H12, Molecular Weight: 96.17. US Biological Life Sciences.
Catalyst used in the selective hydration of substituted alkynes at room temperatures. Catalyst used in the hydroarylating/aromatization of arene-diynes. Highly-efficient and regio-selective catalyst for the selective carbonyl migration in alkynyl-substituted indole-3-carboxamides. Intermolecular gold(I) catalyzed alkyne carboalkoxylation reactions for the multicomponent assembly of β-alkoxy ketones. Gold(I)-catalyzed hydration of alkynylphosphonates: Efficient access to β-ketophosphonates. Gold-catalyzed intramolecular hydroamination reaction. Group: Gold catalysts. Alternative Names: MFCD21608485; 1121960-90-4; Bis(trifluoromethanesulfonyl)imide(2-dicyclohexylphosphino-2', 6'-dimethoxy-1, 1'-biphenyl)gold(I). CAS No. 1121960-90-4. Molecular formula: C28H36AuF6NO6PS2+. Mole weight: 888.648g/mol. IUPACName: bis(trifluoromethylsulfonyl)azanide; dicyclohexyl-[2-(2, 6-dimethoxyphenyl)phenyl]phosphanium; gold(1+). Canonical SMILES: COC1=C (C (=CC=C1)OC)C2=CC=CC=C2[PH+] (C3CCCCC3)C4CCCCC4. C (F) (F) (F)S (=O) (=O)[N-]S (=O) (=O)C (F) (F)F. [Au+]. Catalog: ACM1121960904.
2-Iodo Adenosine 5'-Carboxy-2',3'-acetonide
Used for preparing 2-alkynyl-adenosine nucleosides as potential adenosine receptor agonists. Uses: Used for preparing 2-alkynyl-adenosine nucleosides as potential adenosine receptor agonists. Synonyms: 1-(6-Amino-2-iodo-9H-purin-9-yl)-1-deoxy-2,3-O-(1-methylethylidene)-β-D-ribofuranuronic Acid. Grades: 95%. CAS No. 141018-26-0. Molecular formula: C13H14IN5O5. Mole weight: 447.19.
3-Chloro-4- (2-pyridylmethyloxy) nitrobenzene
3-Chloro-4- (2-pyridylmethyloxy) nitrobenzene was used to synthesize aniline 'headgroups' and incorporat them into an alkynyl thienopyrimidine series of EGFR and ErbB-?2 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 179687-79-7. Pack Sizes: 1g, 5g. Molecular Formula: C12H9ClN2O3, Molecular Weight: 264.66. US Biological Life Sciences.
Ligand used in the cobalt-catalyzed alkenylzincation of unfunctionalized alkynes. Ligand used in the cobalt-catalyzed alkylboration of alkenes. Ligand used in the palladium-catalyzed N-alkylation of amines using primary and secondary alcohols. Ligand used in the palladium-catalyzed methylation of alkynyl C(sp)-H bonds with dimethyl sulfonium ylides. Group: Organic phosphine compounds. Alternative Names: AX8240548; ditert-butyl-(5-ditert-butylphosphanyl-9,9-dimethylxanthen-4-yl)phosphane; SCHEMBL1315091; 4,5-bis(di-t-butylphosphino)-9,9-dimethylxanthene; 9,9-Dimethyl-4,5-bis(di-tert-butylphosphino)xanthene; FT-0728449; ZINC12359415; t-Bu-Xantphos; CS-W009619; DB-009564. CAS No. 856405-77-1. Molecular formula: C31H48OP2. Mole weight: 498.672g/mol. IUPACName: ditert-butyl-(5-ditert-butylphosphanyl-9,9-dimethylxanthen-4-yl)phosphane. Canonical SMILES: CC1 (C2=C (C (=CC=C2)P (C (C) (C)C)C (C) (C)C)OC3=C1C=CC=C3P (C (C) (C)C)C (C) (C)C)C. Catalog: ACM856405771.
Ligand used for the hydroformylation of alkenes. Ligand used in the intermolecular coupling of amides and hydrazones with aryl halides. Ligand used in the intermolecular coupling of amides with aryl halides or triflates. Ligand used in the coupling of heteroarylamines and aryl halides. Ligand used in the hydrophosphinylation of alkenes and alkynes. Ligand used for the Au(I)-catalyzed dehydrogenative silation of alcohols. Ligand used for the sulfinylation of aryl iodides. Ligand used for the Pd-catalyzed carbonylation reaction of aryl bromides and amines. Ligand used for the Ni-cataltzed alkynylcyanation of alkynes. Ligand used for the Pd-catalyzed N-arylation of 3-amino-1H-pyrazole. Ligand used for the Rh-catalyzed dehydrogenation borylation of cyclic alkenes. Ligand used for the Pd-catalyzed intermolecular coupling of H-Phosphonate diesters with benzyl halides. Ligand used for the Pd-catalyzed one pot synthesis of 4-aryl-1H-1,2,3-triazoles. Ligand used for the Pd-catalyzed intermolecular addition of formamides to alkynes. Ligand used for the Pd-catalyzed decarboxylative couplings of 2-(2-azaaryl)acetates with aryl halides and triflates. Ligand used for the Pd-catalyzed benzylic arylation of 2-methyl azaarenes Ligand used for the Pd-catalyzed α-arylation of heteroaromatic ketones. Ligand used for the Pd-catalyzed direct alkynlation of both azoles and azolines. Ligand used fo
AF488 azide
AF488 is a fluorescent dye. AF488 is a fluorophore pH-insensitive over a broad pH range (from 4 to 10). It has an absorption maximum at 495 nm and an emission maximum at 519 nm in the green spectrum region. The dye is hydrophilic and can be used to introduce the fluorescent label into various molecules, including proteins and antibodies. Conjugates of molecules with AF488 have high brightness and photostability and are commonly used in flow cytometry and microscopy. This allows the detection of biological objects with high sensitivity at a longer imaging time.,AF488 azide interacts with alkynyl derivatives of biomolecules in Click Chemistry reactions either in the presence of copper (I) catalyst (with terminal alkynes) or without catalyst (with cyclooctynes), leading to the formation of stable adducts. Grades: NMR 1H, HPLC-MS (95%). CAS No. 1679326-36-3 (with azidohexyl group). Molecular formula: C36H56N8O10S2. Mole weight: 825.01.
beta-GlcNAc-TEG-Alkyne
beta-GlcNAc-TEG-Alkyne is a cutting-edge biomedical compound, incorporating a triethylene glycol (TEG) spacer, playing a pivotal role in the researchs for diverse ailments. Being an alkynylated derivative of beta-GlcNAc, this compound unveils invaluable insights into protein glycosylation and its intricate participation in cellular mechanisms. Molecular formula: C17H29NO9. Mole weight: 391.41.
Biotin-Azide(≥97% )
Biotin azide reacts with the terminal alkynes via a copper-catalyzed click reaction, including biomolecules containing alkyne groups through azide-alkyne cycloaddition. Biotin and biotin derivatives can be readily conjugated to various biomolecules through the well-known click chemistry and subsequently detected with streptavidin, avidin or NeutrAvidin biotin-binding protein. Biotin azide can be used to prepare various biotinylated conjugates via Click Chemistry. Click chemistry contains a class of chemical reactions that use bio-orthogonal or biologically unique moieties to label and detect the molecule in mild and aqueous conditions. This reagent allows labeling of various alkynylated molecules, such as DNA, oligonucleotides, and proteins with biotin. Biotin binding to avidin or streptavidin could be used in downstream affinity applications for the isolation of biotinylated molecules or their binding with streptavidin conjugates [1]. Uses: Useful for biotinylation of reagents. Group: Biotinylation reagents. Alternative Names: Biotin-Azide. CAS No. 1006592-62-6. Molecular formula: C27H49N7O7S. Mole weight: 615.79 g/mol. Appearance: To be determined. Purity: ≥97%. IUPACName: N-(6-azidohexyl)-1-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)-3,6,9,12-tetraoxapentadecan-15-amide. Canonical SMILES: [H][C@@]1 (N2)[C@] ([C@H] (CCCCC (NCCOCCOCCOCCOCCC (NCCCCCCN=[N+]=[N-])=O)=O)SC1) ([H])NC2=
Reagent for the conversion of enynes to bicyclic cyclopentenones. Precursor for the cyclization of dienes to cyclopentane and cyclohexane derivatives. Precatalyst for the alkylation of olefins. Precursor to zirconocene complexes of unsaturated organic molecules. Catalyst for the coupling of alkoxymethyl-substituted styrene derivatives. Reagent for the carboalumination-Claisen rearrangement-carbonyl addition cascade reaction. Useful for the preparation of vinyl allenes. Reagent for the alkynylation of epoxides. Catalyst for the formation of carbocycles from cyclic enol ether. Group: Polymer/macromolecule. Alternative Names: BIS (CYCLOPENTADIENYL) ZIRCONIUMICHLORIDE; BIS (CYCLOPENTADIENYL) ZIRCONIUM (IV) DICHLORIDE; BIS(CYCLOPENTADIENYL)ZIRCONIUM DICHLORIDE; DICHLORODICYCLOPENTADIENYLZIRCONIUM; DICYCLOPENTADIENYLZIRCONIUM DICHLORIDE;ZIRCONOCENE DICHLORIDE; bis(η -cyclopentadienyl)zircon. CAS No. 1291-32-3. Molecular formula: C10H10Cl2Zr. Mole weight: 292.32. Appearance: white to light beige crystals or powder. Purity: 0.96. IUPACName: Bis(cyclopentadienyl)zirconium dichloride. Catalog: ACM1291323.
Bis(triphenylphosphine)palladium(II) Dichloride
Bis(triphenylphosphine)palladium(II) Dichloride. Uses: Precatalyst for the carbonylative cyclization of malonate derivatives. catalyst used in the double allylation of activated olefins. precatalyst for the three-component preparation of 3-arylidene- (or 3-alkenylidene) tetrahydrofurans. precatalyst for the homocoupling of terminal alkynes. precatalyst in the cross-coupling of alkynylsilanols and aryl halides. catalyst for direct pd-catalyzed alkynylation of n-fused heterocycles. catalyst for a tandem heck reaction/c-h functionalization. catalyst for direct arylation of tautomerizable heterocycles. Group: Salt. Alternative Names: TRANS-BIS-(TRIPHENYLPHOSPHINE)PALLADIUM DICHLORIDE; 13965-03-2; 28966-81-6; AC1L36TY; SC-01002; LS-192238; bis(triphenylphosphine) palladiuml(II) dichloride; bis(triphenylphosphine) palladium (II) chloride; FC0823; EINECS 237-744-2. CAS No. 13965-03-2. Product ID: palladium(2+); triphenylphosphane; dichloride. Molecular formula: 701.904g/mol. Mole weight: C36H30Cl2P2Pd. C1=CC=C (C=C1)P (C2=CC=CC=C2)C3=CC=CC=C3. C1=CC=C (C=C1)P (C2=CC=CC=C2)C3=CC=CC=C3. [Cl-]. [Cl-]. [Pd+2]. InChI=1S/2C18H15P. 2ClH. Pd/c2*1-4-10-16 (11-5-1) 19 (17-12-6-2-7-13-17) 18-14-8-3-9-15-18; ; ; /h2*1-15H; 2*1H; /q; ; ; ; +2/p-2. YNHIGQDRGKUECZ-UHFFFAOYSA-L.
Bis(triphenylphosphine)palladium(II) Dichloride
Precatalyst for the carbonylative cyclization of malonate derivatives. Catalyst used in the double allylation of activated olefins. Precatalyst for the three-component preparation of 3-arylidene- (or 3-alkenylidene) tetrahydrofurans. Precatalyst for the homocoupling of terminal alkynes. Precatalyst in the cross-coupling of alkynylsilanols and aryl halides. Catalyst for direct Pd-catalyzed alkynylation of N-fused heterocycles. Catalyst for a tandem Heck reaction/C-H functionalization. Catalyst for direct arylation of tautomerizable heterocycles. Group: Palladium series catalysts. Alternative Names: TRANS-BIS-(TRIPHENYLPHOSPHINE)PALLADIUM DICHLORIDE; 13965-03-2; 28966-81-6; AC1L36TY; SC-01002; LS-192238; bis(triphenylphosphine) palladiuml(II) dichloride; bis(triphenylphosphine) palladium (II) chloride; FC0823; EINECS 237-744-2. CAS No. 13965-03-2. Molecular formula: C36H30Cl2P2Pd. Mole weight: 701.904g/mol. IUPACName: palladium(2+); triphenylphosphane; dichloride. Canonical SMILES: C1=CC=C (C=C1)P (C2=CC=CC=C2)C3=CC=CC=C3. C1=CC=C (C=C1)P (C2=CC=CC=C2)C3=CC=CC=C3. [Cl-]. [Cl-]. [Pd+2]. ECNumber: 237-744-2. Catalog: ACM13965032.
Carbonylchlorobis (triphenylphosphine)iridium (I)
Catalyst for the intramolecular carbonylative [2+2+1] cycloaddition of allenynes. Catalyst for the selective hydrogenation of myrcene. Catalyst for silylation of ortho-functionalized aryl halides with hydrosilanes. Catalyst for synthesis of aldenamines from carboxamides by silane-reduction/dehydration under mild conditions. Hydrogen atom transfer catalyst for radical cyclizations. Complex for photocatalytic alkane dehydrogenation. Catalyst for chemoselective reductive nucleophilic addition to N-methoxyamides. Catalyst for chemoselective reductive alkynylation of tertiary amides. Group: Iridium series of catalysts. Alternative Names: Bis(triphenylphosphine)iridium(I) carbonyl chloride. CAS No. 14871-41-1. Molecular formula: C37H32ClIrOP2. Mole weight: 782.3. Appearance: Crystal. Purity: 0.99. IUPACName: formaldehyde; iridium; triphenylphosphane; chloride. Canonical SMILES: C=O. C1=CC=C (C=C1)P (C2=CC=CC=C2)C3=CC=CC=C3. C1=CC=C (C=C1)P (C2=CC=CC=C2)C3=CC=CC=C3. [Cl-]. [Ir]. ECNumber: 238-941-6. Catalog: ACM14871411-1.
Catalyst for the rearrangement of alkynyl sulfoxides to benzothiepinones Catalyst for the rearrangement of homopropargylic ethers to α,β-unsaturated carbonyl compounds Catalyst for oxidative cyclopropanation of N-Allylynamides to 3-aza-bicyclo[3.1.0]-hexan-2-one derivatives Catalyst for oxidative rearrangement of homopropargylic ethers to cyclobutanones. Group: Gold series of catalysts. Alternative Names: 1,3-Bis(2,4,6-trimethylphenyl)imidazol-2-ylidene gold(I) chloride; Chloro[1,3-Bis(Mesityl)Imidazole-2-Ylidene]Gold(I); Chloro[1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene]gold(I); C21H24AuClN2; Chloro[1,3-bis(2,4,6-trimethylphenyl)2H-imidazol-2-ylidene]gold(I); AuCl(IMes); Chloro(1,3-dimesityl-1H-imidazol-2(3H)-ylidene)aurate(I); 3213AC. CAS No. 852445-81-9. Molecular formula: C21H24AuClN2. Mole weight: 536.854g/mol. IUPACName: [1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene]-chlorogold. Canonical SMILES: CC1=CC (=C (C (=C1)C)N2C=CN (C2=[Au]Cl)C3=C (C=C (C=C3C)C)C)C. Catalog: ACM852445819.
Highly-efficient and regio-selective catalyst for the selective carbonyl migration in alkynyl-substituted indole-3-carboxamides. Catalyst used in the hydroarylation/aromatization of arene-diynes. Catalyst used in the selective hydration of substituted alkynes at room temperatures. Group: Gold catalysts. Alternative Names: MFCD21608486;Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)gold(I);854045-95-7. CAS No. 854045-95-7. Molecular formula: C26H36AuClO2P+. Mole weight: 643.962g/mol. IUPACName: chlorogold;dicyclohexyl-[2-(2,6-dimethoxyphenyl)phenyl]phosphanium. Canonical SMILES: COC1=C (C (=CC=C1)OC)C2=CC=CC=C2[PH+] (C3CCCCC3)C4CCCCC4. Cl[Au]. Catalog: ACM854045957.
Chlorotetrahydrothiophenegold(I)
Alkynylation; C-H Activation; Isomerization. Group: Catalysts for pharmaceutical. CAS No. 39929-21-0. Molecular formula: C4H8ClSAu. Mole weight: 320.59. Appearance: white yellowish. Purity: Metal purity 99.95. Catalog: ACM39929210.
Copper(I) iodide 99+%
Copper (I) Iodide used in the preparation of alkynyl imines and the synthesis of pyrroles and pyrrole heterocycles. It is also used in the synthesis of BTBT derivatives ([1]Benzothieno[3,2-b]benzothiophene) for use as semiconductors in transistors. Group: Biochemicals. Alternative Names: Copper Monoiodide; Copper(1+) Iodide; Copper(I) Iodide; Cuprous Iodide; Cuprous Iodide (CuI). Grades: Reagent Grade. CAS No. 7681-65-4. Pack Sizes: 100g, 250g, 1Kg. Molecular Formula: CuI, Molecular Weight: 190.45. US Biological Life Sciences.
Worldwide
Cyanine5.5 alkyne chloride
Cyanine5.5 alkyne chloride is an alkynyl-modified near-infrared (NIR) fluorescent dye (Ex=678 nm, Em=694 nm). Cyanine5.5 alkyne chloride can react with azides for click chemistry labeling [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1628790-37-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1325.
DP2 Antagonist I (CRTH2 Antagonist I, GPR44 Antagonist I, (4-Chloro-2- ( (2-methyl-5- (propylsulfonyl) phenyl) ethynyl) phenoxy) acetic Acid)
A cell-permeable alkynylphenoxyacetic acid that acts as a high affinity antagonist against the G protein-coupled PGD2 receptor CRTH2/DP2 (Ki = 2.0 and 2.4nM against 1.5nM PGD2 for human & murine DP2 binding, respectively), exhibiting much reduced potency against DP1 (Ki = 1.58uM; IC50 = 10uM), PGE receptor EP2 (54% inhibition at 10uM), and little or no activity toward 49 other receptors and ion channels. Effectively inhibits PGD2-induced cellular activation (IC50 = 32 and 80nM, respectively, using CHO-CRTH2 or human whole blood) in vitro and is efficacious in alleviating airway eosinophil infiltration in OVA-sensitized mice (30mg/kg; p.o.) in vivo with good oral bioavailability. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??ClO?S. US Biological Life Sciences.
Worldwide
DP2 Antagonist II (CRTH2 Antagonist II, GPR44 Antagonist II, (R)-(5-Chloro-1'-(5-chloro-2-fluorobenzyl)-2,2',5'-trioxospiro(indole-3,3?-pyrrolidin)-1(2H)-yl)acetic Acid)
The (R) enantiomer of a cell-permeable alkynylphenoxyacetic acid that acts as a high affinity antagonist against the G protein-coupled PGD2 receptor CRTH2/DP2 (Ki = 5.3 and 5.0nM against human & murine DP2, respectively), exhibiting much reduced potency against a panel of more than 50 other receptors and ion channels. Effectively inhibits DP2-dependent chemotaxis of primary human eosinophils (IC50 = 100nM). Exhibits higher Caco-2 permeability than DP2 Antagonist I, but less oral bioavailability in mice. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??Cl?FN?O?. US Biological Life Sciences.
Worldwide
[NH2Me2][(RuCl((R)-binap))2(μ -Cl)3]
(R)-BINAP or (R)-Tol-BINAP can be combined with dichloro(1,5-cyclooctadiene)ruthenium to form precursors to NOYORI CATALYST SYSTEMS. These systems exhibit very high catalytic activity and enantioselectivity in the hydrogenation of a wide range of substrates. NOYORI CATALYST SYSTEMS have been shown to effect highly enantioselective hydrogenation of functionalized ketones where the substituents are dialkylamino, hydroxy, siloxy, carbonyl, ester, amide or thioester. Useful ligand in asymmetric Heck processes. Ligand employed in palladium-catalyzed asymmetric arylation of ketones. Ligand employed in rhodium-catalyzed 1,4-additions to enones. Ligand employed in palladium-catalyzed hydroamination of styrene derivatives. Ligand employed in silver-catalyzed asymmetric Sakuri-Hosomi allylation and Mukaiyama aldol reaction. Ligand employed in rhodium-catalyzed kinetic resolution of enynes. Ligand employed in asymmetric rhodium-catalyzed hydroboration of cyclopropenes. Ligand employed in silver-catalyzed a-hydroxylation of stannyl enol ethers. Ligand employed in palladium-catalyzed synthesis of chiral allenes. Ligand for palladium-catalyzed enantioselective hetero Michael addition to form b-amino acid derivatives. Ligand employed in rhodium-catalyzed asymmetric rearrangement of alkynyl alkenyl carbinols. Ligand employed in rhodium-catalyzed 1,2-addition of aluminium organyl compounds to cyclic enones. Ligand
[NH2Me2][(RuCl((S)-binap))2(μ -Cl)3]
(R)-BINAP or (R)-Tol-BINAP can be combined with dichloro(1,5-cyclooctadiene)ruthenium to form precursors to NOYORI CATALYST SYSTEMS. These systems exhibit very high catalytic activity and enantioselectivity in the hydrogenation of a wide range of substrates. NOYORI CATALYST SYSTEMS have been shown to effect highly enantioselective hydrogenation of functionalized ketones where the substituents are dialkylamino, hydroxy, siloxy, carbonyl, ester, amide or thioester. Useful ligand in asymmetric Heck processes. 3. Ligand employed in palladium-catalyzed asymmetric arylation of ketones. 4. Ligand employed in rhodium-catalyzed 1,4-additions to enones. 5. Ligand employed in palladium-catalyzed hydroamination of styrene derivatives. 6. Ligand employed in silver-catalyzed asymmetric Sakuri-Hosomi allylation and Mukaiyama aldol reaction. 7. Ligand employed in rhodium-catalyzed kinetic resolution of enynes. 8. Ligand employed in asymmetric rhodium-catalyzed hydroboration of cyclopropenes. 9. Ligand employed in silver-catalyzed a-hydroxylation of stannyl enol ethers. 10. Ligand employed in palladium-catalyzed synthesis of chiral allenes. 11. Ligand for palladium-catalyzed enantioselective hetero Michael addition to form b-amino acid derivatives. 12. Ligand employed in rhodium-catalyzed asymmetric rearrangement of alkynyl alkenyl carbinols. 13. Ligand employed in rhodium-catalyzed 1,2-addition of aluminium organy
Propargylcholine bromide
Propargylcholine bromide is an alkynyl derivative of choline that has a propargyl group in place of one methyl group. It can be used to assay phospholipid synthesis and localization in cells and tissues using Raman scattering microscopy or click chemistry labeling with fluorescent or affinity-tagged azides. Group: Others. CAS No. 111755-76-1. Molecular formula: C7H14BrNO. Mole weight: 208.1. Appearance: Solid powder. Purity: >98%. IUPACName: N-(2-hydroxyethyl)-N,N-dimethyl-2-propyn-1-aminium, monobromide. Canonical SMILES: C#CC[N+](C)(CCO)C.[Br-]. Catalog: ACM111755761.
Propargylcholine bromide
Propargylcholine is an alkynyl derivative of choline. It can be used for detecting phospholipid synthesis and localization in cellsusing click chemistry. Synonyms: 2-Propyn-1-aminium, N-(2-hydroxyethyl)-N,N-dimethyl-, bromide (1:1); 2-Propyn-1-aminium, N-(2-hydroxyethyl)-N,N-dimethyl-, monobromide; N-(2-hydroxyethyl)-N,N-dimethyl-2-propyn-1-aminium monobromide; 2-hydroxyethyl-dimethyl-prop-2-ynylazanium bromide. Grades: ≥95%. CAS No. 111755-76-1. Molecular formula: C7H14NO·Br. Mole weight: 208.10.
(R)-(+)-BINAP
(R)-BINAP or (R)-Tol-BINAP can be combined with dichloro(1,5-cyclooctadiene)ruthenium to form precursors to NOYORI CATALYST SYSTEMS. These systems exhibit very high catalytic activity and enantioselectivity in the hydrogenation of a wide range of substrates. NOYORI CATALYST SYSTEMS have been shown to effect highly enantioselective hydrogenation of functionalized ketones where the substituents are dialkylamino, hydroxy, siloxy, carbonyl, ester, amide or thioester. Useful ligand in asymmetric Heck processes. Ligand employed in palladium-catalyzed asymmetric arylation of ketones. Ligand employed in rhodium-catalyzed 1,4-additions to enones. Ligand employed in palladium-catalyzed hydroamination of styrene derivatives. Ligand employed in silver-catalyzed asymmetric Sakuri-Hosomi allylation and Mukaiyama aldol reaction. Ligand employed in rhodium-catalyzed kinetic resolution of enynes. Ligand employed in asymmetric rhodium-catalyzed hydroboration of cyclopropenes. Ligand employed in silver-catalyzed a-hydroxylation of stannyl enol ethers. Ligand employed in palladium-catalyzed synthesis of chiral allenes. Ligand for palladium-catalyzed enantioselective hetero Michael addition to form b-amino acid derivatives. Ligand employed in rhodium-catalyzed asymmetric rearrangement of alkynyl alkenyl carbinols. Ligand employed in rhodium-catalyzed 1,2-addition of aluminium organyl compounds to cyclic enones. Ligand employed in iridium-cataly
Silver trifluoromethanesulfonate
Silver precatalyst for the asymmetric allylation of aldehydes Silver catalyst for intramolecular additions of alcohols and carboxylic acids to inert olefins Silver catalyst for the fluorination of boronic acids Silver catalyst for the fluorination of functionalized aryl stannanes Silver catalyst for cyclopropenation of internal alkynes with donor/acceptor substituted diazo compounds Silver catalyst for the reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate. Group: Silver series of catalysts. Alternative Names: KSC491Q9D; Silver trifluoromethanesulfonate, >=99%; silver(1+) ion trifluoromethanesulfonate; silver(I)trifluoromethanesulfonate; TRIFLUOROMETHANESULFONATE SILVER SALT; trifluormethanesulfonic acid silver salt; silver(I) trifluoromethanesulphonate; ANW-26574; QRUBYZBWAOOHSV-UHFFFAOYSA-M; X7226. CAS No. 2923-28-6. Molecular formula: CAgF3O3S. Mole weight: 256.94. Appearance: Powder. Purity: 0.98. IUPACName: silver;trifluoromethanesulfonate. Canonical SMILES: C(F)(F)(F)S(=O)(=O)[O-].[Ag+]. ECNumber: 220-882-2. Catalog: ACM2923286-1.
Sodium 4-pentynoate
Sodium 4-pentynoate, an alkynylacetate analogue, can be metabolically incorporated onto cellular proteins through biosynthetic mechanisms for profiling of acetylated proteins in diverse cell types. Synonyms: sodium 4-pentynoate; 101917-30-0; sodium pent-4-ynoate; sodium; pent-4-ynoate; sodium4-pentynoate; CS-0723; SCHEMBL3503732; DTXSID70735352; BCP33409; AKOS030526202; AS-57204; HY-15286; D86943; EN300-178227. Grades: >98%. CAS No. 101917-30-0. Molecular formula: C5H5NaO2. Mole weight: 120.08.
(S,S)-2,6-Bis(4-phenyl-2-oxazolin-2-yl)pyridine
1. Ligand for Copper catalyzed syn-selective Mukaiyama aldol reaction. 2. Ligand for Tin catalyzed anti-selective aldol reaction. 3. Ligand for Ytterbuim catalyzed desymmetrization of meso epoxides. 4. Ligand for Copper catalyzed enantioselective addition of terminal alkynes to imines. 5. Ligand for Scandium catalyzed enantioselective syn-selective ene reactions. 6. Ligand for Copper catalysed asymmetric alkynylation of cyclic azomethine Imines. 7. Ligand for Europium catalyzed asymmetric alpha amination. 8. Ligand for Indium catalyzed enantioselective construction of spiro-fused 2-oxindole/α -methylene-γ -butyrolactones. 9. Ligand for Copper catalyzed asymmetric azide-alkyne cycloaddition to quaternary oxindoles. 10. Ligand for Iron catalyzed enantioselective nitrene transfer to sulfides. 11. Ligand for Copper catalyzed enantioselective intramolecular propargylic amination. 12. Ligand for Copper catalyzed asymmetric hydroxylation. 13. Ligand for Scandium catalyzed dearomatization of 2-naphthols by electrophilic amination. 14. Ligand for Copper catalyzed asymmetric alkynylation of oxocarbenium ions to set diaryl tetrasubstituted stereoceters. Group: Heterocyclic organic compound. Alternative Names: BP-12297; SC-44215; 2,6-BIS[(S)-4-PHENYL-2-OXAZOLIN-2-YL]PYRIDINE; RTR-007742; BR-10750; (S,S)-2,6-Bis(4-phenyl-2-oxazolinyl)pyridine; AB1011206; AJ-35446; ANW-22713; J-010994. CAS No
Tri(2-furyl)phosphine
Useful ligand for C-C coupling reactions. Ligand used for the alkynylation of thioesters. Ligand used for enol ester formation. Ligand for palladium-catalyzed 3-Component coupling. Ligand for palladium-catalyzed C-C coupling reaction. Ligand for trans-olefin formation. Olefin formation from N-tosylhydrazones and benzyl halides. C-H arylation/alkenylation of 1-substituted tetrazoles. Group: Organic phosphine compounds. Alternative Names: Trifurylphosphine. CAS No. 5518-52-5. Molecular formula: C12H9O3P. Mole weight: 232.17. Appearance: Solid. Purity: 0.98. IUPACName: tris(furan-2-yl)phosphane. Canonical SMILES: C1=COC(=C1)P(C2=CC=CO2)C3=CC=CO3. Catalog: ACM5518525-1.
Triphenylphosphinegold(I) bis (trifluoromethanesulfonyl)imidate, min. 98%
Catalyst promoting the addition of nucleophiles to alleneamides. Gold- and Bronsted acid-catalyzed cycloisomerization of 1,8-diynyl vinyl acetates to bicycle[2.2.1]hept-2-en-7-ones. Catalyst used for the synthesis of spiro[piperidine-3,3'-oxindoles]. Catalyst used in the gold(I)-catalyzed Rautenstrauch rearrangement. Gold-catalyzed π-directed regioselective cyclization of bis(o-alkynyl benzyl alcohols): rapid excess to dihydroisobenzofuran derivatives. Gold compound used in acid-catalyzed cycloisomerization - synthesis of diverse nitrogen-containing spiro heterocycles. Gold catalyst used in the domino synthesis of functionalized benzofurans and tetracyclic isochromans via formal carboalkoxylation. Group: Gold series of catalysts. CAS No. 866395-16-6. Molecular formula: C20H15AuF6NO4PS2. Mole weight: 739.4. Appearance: white to off-white powder. Purity: 0.99. Catalog: ACM866395166.
Z-Glycinol
An intermediate in the synthesis of alkynylaryladenines, which are A2A adenosine receptor agonists. Synonyms: 2-(Z-amino)ethanol; Z-ethanolamine; Benzyl N-(2-hydroxyethyl)carbamate; Benzyl (2-hydroxyethyl)carbamate; N-Z-Ethanolamine. Grades: ≥ 99 % (HPLC). CAS No. 77987-49-6. Molecular formula: C10H13NO3. Mole weight: 195.18.
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