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Cytosolic or membrane-associated enzyme from mammalian tissues, activated by chloride ions and low concentrations of thiol compounds. This is one of the activities of the bifunctional enzyme EC 3.3.2.6 (membrane alanyl aminopeptidase family). Group: Enzymes. Synonyms: arylamidase II; arginine aminopeptidase; arginyl aminopeptidase; Cl--activated arginine aminopeptidase; cytosol aminopeptidase IV; L-arginine aminopeptidase. Enzyme Commission Number: EC 3.4.11.6. CAS No. 9073-92-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4027; aminopeptidase B; EC 3.4.11.6; 9073-92-1; arylamidase II; arginine aminopeptidase; arginyl aminopeptidase; Cl--activated arginine aminopeptidase; cytosol aminopeptidase IV; L-arginine aminopeptidase. Cat No: EXWM-4027.
Aminopeptidase N Inhibitor
Membrane alanyl aminopeptidase is also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N), which is an enzyme that in humans is encoded by the ANPEP gene. Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), γ-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 μM. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. Synonyms: AP-N Inhibitor. Grade: ≥95%. CAS No. 596108-59-7. Molecular formula: C17H10N2O8. Mole weight: 370.27.
bacterial leucyl aminopeptidase
A zinc enzyme. Forms of the enzyme have been isolated from Aeromonas proteolytica, Escherichia coli and Streptococcus thermophilus. Examples are known from peptidase families M17 and M28 (of leucyl aminopeptidase and aminopeptidase Y, respectively). Group: Enzymes. Synonyms: Aeromonas proteolytica aminopeptidase. Enzyme Commission Number: EC 3.4.11.10. CAS No. 37288-67-8. Aminopeptidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4008; bacterial leucyl aminopeptidase; EC 3.4.11.10; 37288-67-8; Aeromonas proteolytica aminopeptidase. Cat No: EXWM-4008.
β-peptidyl aminopeptidase
Sphingosinicella xenopeptidilytica strain 3-2W4 is able to utilize the β-peptides β-homoVal-β-homoAla-β-homoLeu and β-homoAla-β-homoLeu as sole carbon and energy sources. Group: Enzymes. Synonyms: BapA (ambiguous). Enzyme Commission Number: EC 3.4.11.25. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4022; β-peptidyl aminopeptidase; EC 3.4.11.25; BapA (ambiguous). Cat No: EXWM-4022.
membrane alanyl aminopeptidase
A zinc enzyme, not activated by heavy metal ions. Type example of peptidase family M1. Group: Enzymes. Synonyms: microsomal aminopeptidase; aminopeptidase M; aminopeptidase N; particle-bound aminopeptidase; amino-oligopeptidase; alanine aminopeptidase; membrane aminopeptidase I; pseudo leucine aminopeptidase; alanyl aminopeptidase; alanine-specific aminopeptidase; cysteinylglycine dipeptidase; cysteinylglycinase; L-alanine aminopeptidase; CD13. Enzyme Commission Number: EC 3.4.11.2. CAS No. 9054-63-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4016; membrane alanyl aminopeptidase; EC 3.4.11.2; 9054-63-1; microsomal aminopeptidase; aminopeptidase M; aminopeptidase N; particle-bound aminopeptidase; amino-oligopeptidase; alanine aminopeptidase; membrane aminopeptidase I; pseudo leucine aminopeptidase; alanyl aminopeptidase; alanine-specific aminopeptidase; cysteinylglycine dipeptidase; cysteinylglycinase; L-alanine aminopeptidase; CD13. Cat No: EXWM-4016.
Methionine Aminopeptidase from Pyrococcus furiosus, Recombinant
Methionyl aminopeptidase (EC 3.4.11.18, methionine aminopeptidase, peptidase M, L-methionine aminopeptidase, MAP) is an enzyme. This enzyme catalyses the following chemical reaction:Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. This membrane-bound enzyme is present in both prokaryotes and eukaryotes. X-ray crystallography of the structure of methionine aminopeptidase from pyrococcus furiosus or pfmap was performed at a resolution of 1.75a and showed that the protein consists of a catalytic domain containing two cobalt ions in the active site and a unique insertion domain which is specific to the prokaryotic form of...o the methionyl aminopeptidases from escherichia coli and pyrococcus furiosus. it has also been used in a study to examine the binding of a new class of pseudopeptide analog inhibitors. Group: Enzymes. Synonyms: Methionyl aminopeptidase; EC 3.4.11.18; methionine aminopeptidase; peptidase M; L-methionine aminopeptidase; MAP. Enzyme Commission Number: EC 3.4.11.18. CAS No. 9025-42-7. MAP. Storage: -20°C. Form: Solution containing 0.01% Tween 20, 0.1 mM CoCl2, and 10 mM Tris-HCl, pH 7.5. Source: E. coli. Species: Pyrococcus furiosus. Methionyl aminopeptidase; EC 3.4.11.18; methionine aminopeptidase; peptidase M; L-methionine aminopeptidase; MAP. Cat No: NATE-0442.
Native Bacillus sp. Pyroglutamate Aminopeptidase
Pyroglutamate aminopetidase is an enzyme that digests proteins. Applications: Pyroglutamate aminopetidase is used to digest proteins for subsequent analysis, such as amino acid sequencing. pyroglutamate aminopeptidase is used to hydrolyze and activate various prodrugs. Group: Enzymes. Synonyms: pyroglutamyl-peptidase I; Pyroglutamate aminopeptidase; EC 3.4.19.3; 5-oxoprolyl-peptidase; pyrase; pyroglutamate aminopeptidase; pyroglutamyl aminopeptidase; L-pyroglutamyl peptide hydrolase; pyrrolidone-carboxyl peptidase; pyrrolidone-carboxylate peptidase; pyrrolidonyl peptidase; L-pyrrolidonecarboxylate peptidase; pyroglutamidase; pyrrolidonecarboxylyl peptidase; 9075-21-2. Enzyme Commission Number: EC 3.4.19.3. CAS No. 9075-21-2. Pyrase. Activity: > 0.11 units/mg protein. Storage: -20°C. Source: Bacillus sp. pyroglutamyl-peptidase I; Pyroglutamate aminopeptidase; EC 3.4.19.3; 5-oxoprolyl-peptidase; pyrase; pyroglutamate aminopeptidase; pyroglutamyl aminopeptidase; L-pyroglutamyl peptide hydrolase; pyrrolidone-carboxyl peptidase; pyrrolidone-carboxylate peptidase; pyrrolidonyl peptidase; L-pyrrolidonecarboxylate peptidase; pyroglutamidase; pyrrolidonecarboxylyl peptidase; 9075-21-2. Cat No: NATE-0647.
PepB aminopeptidase
A 270-kDa protein composed of six 46.3-kDa subunits. The pH optimum is in the alkaline range and activity is stimulated by KCl. In peptidase family M17. Group: Enzymes. Synonyms: Salmonella enterica serovar Typhimurium peptidase B. Enzyme Commission Number: EC 3.4.11.23. CAS No. 928346-44-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4020; PepB aminopeptidase; EC 3.4.11.23; 928346-44-5; Salmonella enterica serovar Typhimurium peptidase B. Cat No: EXWM-4020.
TNP-470 (AGM-1470, O-(Chloroacetyl-carbamoyl)fumagillol, AGM1470, MetAP-2 Inhibitor II, MetAP2 Inhibitor II, Methionine Aminopeptidase 2 Inhibitor II, TNP470)
A cell-permeable Fumagillin analog that inhibits MetAP2, but not MetAP1, methionine aminopeptidase activity (IC50 = 1nM against human MetAP2), without affecting the inhibitory activity of MetAP2 against HRI- (heme-regulated inhibitor kinase) catalyzed eIF-2alpha phosphorylation. A potent endothelial cytostasis inducer (IC50 = 25 pM and 37 pM, respectively, against HUVEC and bovine BAEC) in vitro and an effective anti-angiogenesis agent in vivo (2-100mg/kg in mice and rats; s.c.). Group: Biochemicals. Grades: Highly Purified. CAS No. 129298-91-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
2-Methoxy-4-nitrobenzonitrile
2-Methoxy-4-nitrobenzonitrile is a dual and selective inhibitor of dynamin-related protein 1 (Drp1) and puromycin-sensitive aminopeptidase (PSA). Group: Biochemicals. Grades: Highly Purified. CAS No. 101084-96-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H6N2O3, Molecular Weight: 178.14. US Biological Life Sciences.
Worldwide
A 357300 hydrochloride
A 357300 hydrochloride is a potent and reversible inhibitor of methionine aminopeptidase-2 (MetAP-2). In murine models, it significantly inhibits CHP-134-derived neuroblastoma s.c. xenograft growth rate with a treatment-to-control (T/C) ratio at day 24 of 0.19 (P < 0.001) without toxicity. Uses: Novel treatment of neuroblastoma. Synonyms: A-357300; A 357300; A357300; N'-(3-amino-2-hydroxy-5-(isopropylthio)pentanoyl)-3-chlorobenzohydrazide hydrochloride. Grade: 99%. CAS No. 369358-07-6. Molecular formula: C15H22ClN3O3S.HCl. Mole weight: 396.33.
Acetyl 1-L-leucyL-L-arginine
Acetyl 1-L-leucyL-L-arginine is a lactone compound isolated from the Bacterium sp. BMG520-yF2. Acetyl 1-L-leucyL-L-arginine has the activity of inhibiting dipeptidyl aminopeptidase ?. Molecular formula: C14H27N5O3. Mole weight: 313.39.
Actinonin
Actinonin, a natural antibacterial agent produced by Actinomyces, is a potent reversible peptide deformylase (PDF) inhibitor with Ki of 0.28 nM. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin induces apoptosis and has antiproliferative and antitumor activities. Uses: Anti-bacterial agents. Synonyms: 3-[[1-[(2-(Hydroxymethyl)-1-pyrrolidinyl)carbonyl]-2-methylpropyl]carbamoyl]octanohydroxamic acid. Grade: ≥98% by TLC. CAS No. 13434-13-4. Molecular formula: C19H35N3O5. Mole weight: 385.51.
Ala-Ala-OMe HCl
Substrate for dipeptidyl aminopeptidase I (cathepsin C). Synonyms: L-Alanyl-L-alanine methyl ester hydrochloride. Grade: ≥ 98% (TLC). CAS No. 41036-19-5. Molecular formula: C7H14N2O3·HCl. Mole weight: 210.66.
Amastatin
Amastatin is a naturally occurring, competitive and reversible aminopeptidase inhibitor. Amastatin has originally been isolated from the culture filtrate of Streptomyces sp. Amastatin has been shown to slightly decrease the conversion of angiontensin II to angiotensin III, but significantly increases the potency of angiotensin III and des(Asp1)angiotensin I. Uses: Protease inhibitors. Synonyms: (2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl-val-val-asp-OH; [(2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl]-L-valyl-L-valyl-L-aspartic acid; (amino-2-hydroxy-5-methyl-hexanoyl)-L-valyl-L-valyl-L-aspartic acid. Grade: 95%. CAS No. 67655-94-1. Molecular formula: C21H38N4O8. Mole weight: 474.55.
Amastatin hydrochloride
Amastatin, also known as 3-amino-2-hydroxy-5-methylhexanoyl-L-valyl-L-valyl-L-aspartic acid, is a naturally occurring, competitive and reversible aminopeptidase inhibitor. Amastatin has originally been isolated from the culture filtrate of Streptomyces sp. ME98-M3 and is a competitive inhibitor of human serum aminopeptidase A (Ki = 1.1 · 10?? M) and of pig kidney leucine aminopeptidase (Ki = 1.6 · 10?? M). Amastatin hydrochloride has been shown to slightly decrease the conversion of angiontensin II to angiotensin III, but significantly increases the potency of angiotensin III and des(Asp1)angiotensin I. Synonyms: BIMI-1803; J-000280; ZX-AFC000547; Amastatin HCl. Grade: ≥95%. CAS No. 100938-10-1. Molecular formula: C21H39ClN4O8. Mole weight: 511.01.
Amastatin hydrochloride
Amastatin hydrochloride is a slow, tight binding, competitive aminopeptidase (AP) inhibitor with K i values of 0.26 nM, 30 nM, 52 nM for Aeromonas aminopeptidase, cytosolic leucine aminopeptidase, microsomal aminopeptidase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100938-10-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-115194.
aminopeptidase I
A 640-kDa, dodecameric enzyme best known as the major vacuolar aminopeptidase of yeast, Saccharomyces cervisiae, in which species it was first given the name aminopeptidase I (one), amongst others. Activity is stimulated by both Zn2+ and Cl- ions. Type example of peptidase family M18. Group: Enzymes. Synonyms: aminopeptidase III; aminopeptidase yscI; leucine aminopeptidase IV; yeast aminopeptidase I. Enzyme Commission Number: EC 3.4.11.22. CAS No. 9031-94-1. Aminopeptidase I. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4019; aminopeptidase I; EC 3.4.11.22; 9031-94-1; aminopeptidase III; aminopeptidase yscI; leucine aminopeptidase IV; yeast aminopeptidase I. Cat No: EXWM-4019.
Aminopeptidase M
Inhibition of aminopeptidase M (AMP) is being studied for its potential to treat various diseases, including aggressively growing cancer types that have a high degree of blood vessel formation. Synonyms: Microsomal aminopeptidase; Aminopeptidase, microsomal; L-Alanine aminopeptidase; L-Alanylaminopeptidase; Alanine aminopeptidase (3.4.11.2); Alanine aminopeptidases; Alanine-specific aminopeptidase; Alanine-specific aminopeptidases; Alanyl aminopeptidase; Alanyl aminopeptidases; Aminopeptidase M (EC 3.4.11.2); Aminopeptidase M 2; Aminopeptidase M II; Aminopeptidase N; Aminopeptidase N (EC 3.4.11.2); Aminopeptidase PepN; ANPEP; Antigens, CD13; Brush border membrane antigen CD13; CD antigens, CD13; CD13; CD13 antigen; CD13 antigens; Membrane alanyl aminopeptidase; Microsomal aminopeptidases; Myeloid plasma membrane glycoprotein CD13; PepN; Peptidase M; Vp165 aminopeptidase; Vp165 aminopeptidases; Leucine Aminopeptidase, microsomal from porcine kidney. CAS No. 9054-63-1. Molecular formula: C57H41N5Si. Mole weight: 824.1.
aminopeptidase S
Aminopeptidases are associated with many biological functions, including protein maturation, protein degradation, cell-cycle control and hormone-level regulation. This enzyme contains two zinc molecules in its active site and is activated by Ca2+. In the presence of Ca2+, the best substrates are Leu-Phe, Leu-Ser, Leu-pNA (aminoacyl-p-nitroanilide), Phe-Phe-Phe and Phe-Phe. Peptides with proline in the P1' position are not substrates. Belongs in peptidase family M28. Group: Enzymes. Synonyms: Mername-AA022 peptidase; SGAP; aminopeptidase (Streptomyces griseus); Streptomyces griseus aminopeptidase; S. griseus AP; double-zinc aminopeptidase. Enzyme Commission Number: EC 3.4.11.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4021; aminopeptidase S; EC 3.4.11.24; Mername-AA022 peptidase; SGAP; aminopeptidase (Streptomyces griseus); Streptomyces griseus aminopeptidase; S. griseus AP; double-zinc aminopeptidase. Cat No: EXWM-4021.
aminopeptidase Y
Requires Co2+; inhibited by Zn2+ and Mn2+. An enzyme best known from Saccharomyces cerevisiae that hydrolyses Lys-NHPhNO2 and, more slowly, Arg-NHPhNO2. Type example of peptidase family M28. Group: Enzymes. Synonyms: aminopeptidase Co; aminopeptidase (cobalt-activated); lysyl aminopeptidase. Enzyme Commission Number: EC 3.4.11.15. CAS No. 114796-97-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4011; aminopeptidase Y; EC 3.4.11.15; 114796-97-3; aminopeptidase Co; aminopeptidase (cobalt-activated); lysyl aminopeptidase. Cat No: EXWM-4011.
Angiotensin III (human, mouse)
Angiotensin III (Ang III) is generated from Ang II by APA (and subsequently degraded by aminopeptidase N), and that central Ang III seems to play a key-role in vasopressin release and BP control. Angiotensin III, human, mouse is a heptapeptide agonist, which acts as an endogenous angiotensin type 2 receptor (AT2R) agonist. The IC50 values for AT2R is 0.648 nM and the IC50 values for AT1R is 21.1 nM. The biologically active COOH-terminal heptapeptide angiotensin III is bound more tightly than angiotensin II. Synonyms: H-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; Ang III; Angiotensin III; 5-Ile-angiotensin III; 1-Desaspartyl-5-isoleucine angiotensin II; Des-asp(1)-(Ile(5))-angiotensin II; N5-(Diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; 2-8-angiotensin II, 5-L-isoleucine-. Grade: ≥95%. CAS No. 13602-53-4. Molecular formula: C46H66N12O9. Mole weight: 931.09.
ARM1 hydrobromide
ARM1 hydrobromide is a novel Leukotriene A4 hydrolase/aminopeptidase (LTA4H) inhibitor (IC50 value of ~0.5 μM in human neutrophils, and Ki value of 2.3 μM for purified LTA4H) that blocks the conversion of LTA4 into proinflammatory mediator LTB4, although leaving the aminopeptidase activity intact for cleavage and inactivation of Pro-Gly-Pro. Synonyms: ARM1 hydrobromide; ARM 1 hydrobromide; ARM-1 hydrobromide; 4-(4-benzylphenyl)-1,3-thiazol-2-amine hydrobromide. Grade: 99%. CAS No. 1049743-03-4. Molecular formula: C16H14N2S.HBr. Mole weight: 347.27.
Arphamenine A
Arphamenine A is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]benzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, [S-(R*,S*)]-; Arphamenin A. Grade: ≥95%. CAS No. 96551-81-4. Molecular formula: C16H24N4O3. Mole weight: 320.39.
Arphamenine A hemisulfate
Arphamenine A hemisulfate is the salt of Arphamenine A, which is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Arphamenine A sulfate; Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, (αR)-, sulfate (2:1); Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, sulfate, [S-(R*,S*)]-; (2R,5S)-5-Amino-2-benzyl-8-[(diaminomethylene)amino]-4-oxooctanoic acid sulfate (2:1). Grade: >98%. CAS No. 144110-37-2. Molecular formula: C16H24N4O3.1/2H2O4S. Mole weight: 369.43.
Arphamenine A hydrochloride
Arphamenine A hydrochloride is the salt of Arphamenine A, which is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, monohydrochloride, [S-(R*,S*)]-; Arphamenine A monohydrochloride; (2R,5S)-5-Amino-2-benzyl-8-[(diaminomethylene)amino]-4-oxooctanoic acid hydrochloride (1:1); Benzenepropanoic acid, α-[(3S)-3-amino-6-[(diaminomethylene)amino]-2-oxohexyl]-, (αR)-, hydrochloride (1:1). Grade: ≥95%. CAS No. 85713-14-0. Molecular formula: C16H24N4O3.HCl. Mole weight: 356.85.
Arphamenine B
Arphamenine B is a specific inhibitor of aminopeptidase B, which is first isolated from bacteria. Arphamenine B shares the same properties as the aminopeptidase inhibitors bestatin and amastatin, both of which enhance the immune response. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, [S-(R*,S*)]-; Arphamenin B. Grade: 95%. CAS No. 103900-19-2. Molecular formula: C16H24N4O4. Mole weight: 336.39.
Arphamenine B hemisulfate
Arphamenine B is a specific inhibitor of aminopeptidase B, which is first isolated from bacteria. Arphamenine B Hemisulfate is the hemisulfate form. Arphamenine B share the same property with aminopeptidase inhibitors bestatin and amastatin, they all enhance imune responses. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-, sulfate (2:1) (salt); Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, monohydrochloride, [S-(R*,S*)]-, sulfate (2:1) (salt); Arphamenine B sulfate; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid, sulfate (2:1) (salt). Grade: ≥95%. CAS No. 144110-38-3. Molecular formula: C16H24N4O4·1/2H2SO4. Mole weight: 385.43.
Arphamenine B hydrochloride
Arphamenine B is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, monohydrochloride, [S-(R*,S*)]-; Arphamenine B monohydrochloride; Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-, monohydrochloride; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid monohydrochloride. Grade: ≥95%. CAS No. 88465-81-0. Molecular formula: C16H24N4O4.HCl. Mole weight: 372.85.
Bestatin
Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Ubenimex. CAS No. 58970-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0134.
Bestatin
Bestatin is a specific aminopeptidase B inhibitor produced by Streptomyces olivoreticuli. Bestatin is a potent aminopeptidase-B and leukotriene (LT) A4 hydrolase inhibitor used in the treatment of acute myelocytic leukemia. It exhibits potential immunomodulatory and antitumor activities. Uses: The treatment of acute myelocytic leukemia. Synonyms: Ubenimex. Grade: >98%. CAS No. 58970-76-6. Molecular formula: C16H24N2O4. Mole weight: 308.37.
Bestatin
Bestatin is "pseudo"-dipeptide isolated from Streptomyces olivreticuli in 1976. Bestatin is potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin acts as an immunomodulator by activation of macrophages and T-lymphocytes. Bestatin also exhibits good antitumor activity and is under clinical investigation. Group: Biochemicals. Grades: Highly Purified. CAS No. 58970-76-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Bestatin hydrochloride
Bestatin hydrochloride is a competitive aminopeptidase inhibitor, which is studied for use in the treatment of acute myelocytic leukemia. It has become a useful tool in elucidating the physiological role of some mammalian exopeptidases in the regulation of the immune system, in the growth of tumors and their invasion of surrounding tissues, and in the degradation of cellular proteins. Synonyms: Aminopeptidase inhibitor; leucine aminopeptidase; aminopeptidase B; NK-421. Grade: >98%. CAS No. 65391-42-6. Molecular formula: C16H24N2O4.HCl. Mole weight: 344.83.
Bestatin hydrochloride
Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase , used for cancer research. Uses: Scientific research. Group: Natural products. Alternative Names: Ubenimex hydrochloride. CAS No. 65391-42-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0134A.
Bestatin trifluoroacetate
Bestatin, also known as Ubenimex (INN), is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia. Bestatin can be administered, with low toxicity, to cultured cells, intact animals and humans. It has become a useful tool in elucidating the physiological role of some mammalian exopeptidases in the regulation of the immune system, in the growth of tumors and their invasion of surrounding tissues, and in the degradation of cellular proteins. Synonyms: Ubenimex trifluoroacetate. Grade: >98%. CAS No. 223763-80-2. Molecular formula: C18H25F3N2O6. Mole weight: 422.4.
bleomycin hydrolase
The molecule is a homohexamer in which the monomers have a papain-like tertiary structure (in peptidase family C1). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain. Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity. Known from bacteria as well as eukaryotic organisms. Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyses Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates. Group: Enzymes. Synonyms: aminopeptidase C (Lactococcus lactis). Enzyme Commission Number: EC 3.4.22.40. CAS No. 53096-17-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4215; bleomycin hydrolase; EC 3.4.22.40; 53096-17-6; aminopeptidase C (Lactococcus lactis). Cat No: EXWM-4215.
Boc-(S)-2-amino-3-hydroxy-3-methylbutanoic acid
Boc-(S)-2-amino-3-hydroxy-3-methylbutanoic acid is used as a reagent in the synthesis of metabolites of PPI-2458, which is a selective, irreversible inhibitor of methionine aminopeptidase-2 (MetAP2). N-Boc-3-hydroxy-L-valine is also used in the preparation of Boceprevir, an NS3 serine protease inhibitor of hepatitis C virus for the treatment of HCV infection. Synonyms: Boc-L-Ser(3,3-dimethyl)-OH; (S)-Boc-β,β-dimethyl-serine; N-[(1,1-Dimethylethoxy)carbonyl]-3-methyl-L-threonine; N-[(1,1-Dimethylethoxy)carbonyl]-3-hydroxy-L-valine; (S)-2-(tert-Butoxycarbonylamino)-3-hydroxy-3-methylbutanoic Acid; n-boc-(s)-2-amino-3-hydroxy-3-methylbutanoic acid; (S)-2-N-Boc-amino-3-hydroxy-3-methylbutyric acid; (S)-N-Boc-2-Amino-3-hydroxy-3-methylbutanoic acid; L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-3-hydroxy-; L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-; N-(tert-butoxycarbonyl)-3-hydroxy-L-valine; (2S)-2-(N-tert-Butoxycarbonyl)amino-3-hydroxy-3-methylbutanoic acid; N-boc-3-hydroxy-L-valine. Grade: ≥ 98% (Assay). CAS No. 102507-13-1. Molecular formula: C10H19NO5. Mole weight: 233.26.
Bradykinin (2-9)
Bradykinin (2-9) is an amino-truncated Bradykinin peptide. Bradykinin (2-9) is a metabolite of Bradykinin, cleaved by Aminopeptidase P. Uses: Scientific research. Group: Peptides. Alternative Names: Des-Arg1-bradykinin. CAS No. 16875-11-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1490.
Bradykinin 2-9
Bradykinin 2-9, a metabolite of Bradykinin, is an amino-truncated Bradykinin peptide cleaved by Aminopeptidase P. Synonyms: Des-Arg1-bradykinin; H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; Bradykinin fragment 2-9; 2-9-Bradykinin. Grade: ≥95%. CAS No. 16875-11-9. Molecular formula: C44H61N11O10. Mole weight: 904.02.
Bu-2743E
Bu-2743E is a leucine aminopeptidase (LAP) inhibitor originally isolated from Bacillus circulans J725-B93. It inhibits the LAP with an IC50 of 0.51 μg/mL. Synonyms: (2,3-Dihydroxybenzoyl)-L-alanyl-L-threonine. CAS No. 88167-28-6. Molecular formula: C14H18N2O7. Mole weight: 326.30.
cytosol alanyl aminopeptidase
A puromycin-sensitive, Co2+-activated zinc-sialoglycoprotein that is generally cytosolic. Multiple forms are widely distributed in mammalian tissues and body fluids. In peptidase family M1 (membrane alanyl aminopeptidase family). Group: Enzymes. Synonyms: arylamidase; aminopolypeptidase; thiol-activated aminopeptidase; human liver aminopeptidase; puromycin-sensitive aminopeptidase; soluble alanyl aminopeptidase; cytosol aminopeptidase III; alanine aminopeptidase. Enzyme Commission Number: EC 3.4.11.14. CAS No. 243859-94-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4010; cytosol alanyl aminopeptidase; EC 3.4.11.14; 243859-94-1; arylamidase; aminopolypeptidase; thiol-activated aminopeptidase; human liver aminopeptidase; puromycin-sensitive aminopeptidase; soluble alanyl aminopeptidase; cytosol aminopeptidase III; alanine aminopeptidase. Cat No: EXWM-4010.
DG-051
DG-051 is a potent, orally bioavailable leukotriene A4 hydrolase (LTA4H) inhibitor, the enzyme that catalyzes the rate-determining step in the synthesis of LTB4. HDG-051 does not show any inhibitory activity against a panel of more than 50 additional aminopeptidases, ion channels, or HERG. Synonyms: UNII-28B7Y5Y8EF; 28B7Y5Y8EF; 4-((S)-2-((4-(4-chlorophenoxy)phenoxy)Methyl)pyrrolidin-1-yl)butanoic acid hydrochloride. Grade: ≥98%. CAS No. 929915-58-2. Molecular formula: C21H24ClNO4·HCl. Mole weight: 426.3.
dipeptidyl-peptidase III
A cytosolic peptidase that is active at neutral pH. It has broad activity on peptides, although it is highly selective for Arg-Arg-2-naphthylamide, at pH 9.2. Active in the hydrolysis of enkephalins. A metallopeptidase, the type example of peptidase family M49. Group: Enzymes. Synonyms: dipeptidyl aminopeptidase III; dipeptidyl arylamidase III; enkephalinase B; red cell angiotensinase. Enzyme Commission Number: EC 3.4.14.4. CAS No. 77464-87-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4049; dipeptidyl-peptidase III; EC 3.4.14.4; 77464-87-0; dipeptidyl aminopeptidase III; dipeptidyl arylamidase III; enkephalinase B; red cell angiotensinase. Cat No: EXWM-4049.
Dipeptidyl Peptidase IV from Human, Recombinant
Native DPPIV is a ubiquitous type II transmembrane glycoprotein and a serine protease of the S9 prolyl-oligopeptidase family. In vivo, it is synthesized with a signal peptide, which functions as the membrane anchoring domain. There is an 88% sequence homology between the human and porcine kidney enzymes. Both exist as homodimers with a subunit molecular weight of ~30 kDa. The high mannose 100 kDa DPPIV precursor is processed in the Golgi to yield a 124 kDa heavily N-and O-linked mature glycoprotein. It is then sorted to the apical membrane through the concerted action of both N-and O-linked glycans and its association with lipid microdomains. The porcine enzyme contai...zyme from creative enzymes has been used to study the lc-ms (liquid chromatography-mass spectrometry) based assay method for dpp-iv inhibitor screening and substrate discovery. Group: Enzymes. Synonyms: EC 3.4.14.5; 54249-88-6; DPPIV; DPP4; dipeptidyl aminopeptidase IV; Xaa-Pro-dipeptidyl-aminopeptidase; Gly-Pro naphthylamidase; postproline dipeptidyl aminopeptidase IV; lymphocyte antigen CD26; glycoprotein GP110; dipeptidyl peptidase IV; glycylproline aminopeptidase; glycylproline aminopeptidase; X-prolyl dipeptidyl aminopeptidase; pep X; leukocyte antigen CD26; glycylprolyl dipeptidylaminopeptidase; dipeptidyl-peptide hydrolase; glycylprolyl aminopeptidase; dipeptidy
DL-Pyroglutamic acid
Pyroglutamic acid (also known as PCA, 5-oxoproline, pidolic acid, or pyroglutamate for its basic form) is an uncommon and little studied amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam. It is a metabolite in the glutathione cycle that is converted to glutamate by 5-oxoprolinase. Pyroglutamate is found in many proteins including bacteriorhodopsin. N-terminal glutamic acid and glutamine residues can spontaneously cyclize to become pyroglutamate. This is one of several forms of blocked N-terminals which present a problem for N-terminal sequencing using Edman chemistry, which requires a free primary amino group not present in pyroglutamic acid. The enzyme pyroglutamate aminopeptidase can restore a free N-terminus by cleaving off the pyroglutamate residue. Synonyms: DL-Pyroglutamic acid; 149-87-1; 5-Oxopyrrolidine-2-carboxylic acid; 2-Pyrrolidone-5-carboxylic acid; 5-Oxo-DL-proline; 5-OXOPROLINE; DL-Proline, 5-oxo-; DL-2-Pyrrolidone-5-carboxylic acid; DL-Glutamic Acid Lactam; dl-pyrrolidonecarboxylic acid; 6VT1YZM21H; CHEBI:16010; D-(+)-Pyroglutamic Acid; MFCD00064322; NSC-40887; OXOPROLINE; DL-Pidolic acid; 5-Oxo-L-proline-d5; UNII-6VT1YZM21H; DL-5-Oxoprolin. Grade: ? 95%. CAS No. 149-87-1. Molecular formula: C5H7NO3. Mole weight: 129.11.
DL-tryptophan amide hydrochloride
DL-tryptophan amide hydrochloride. Uses: An amino acid amide used as a substrate for studying the action of aminopeptidase enzyme. note: the isomer l-tryptophanamide, hydrochloride is also available as catalogue number t895505. Synonyms: DL-Trp-NH2 HCl; 2-amino-3-(1H-indol-3-yl)propanamide hydrochloride. Grade: ≥ 99% (TLC). CAS No. 67607-61-8. Molecular formula: C11H13N3O·HCl. Mole weight: 239.70.
D,L-Tryptophanamide, Hydrochloride
An amino acid amide used as a substrate for studying the action of aminopeptidase enzyme.Note: The isomer L-Tryptophanamide, Hydrochloride is also available as Catalogue Number T895505. Group: Biochemicals. Grades: Highly Purified. CAS No. 67607-61-8. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
D-stereospecific aminopeptidase
Known from the bacterium Ochrobactrum anthropi. In peptidase family S12 (D-Ala-D-Ala carboxypeptidase family). Group: Enzymes. Synonyms: D-aminopeptidase. Enzyme Commission Number: EC 3.4.11.19. CAS No. 57534-78-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4015; D-stereospecific aminopeptidase; EC 3.4.11.19; 57534-78-8; D-aminopeptidase. Cat No: EXWM-4015.
ERAP1-IN-1
ERAP1-IN-1 is an inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1), an enzyme that trims peptides loaded into classical and nonclassical MHC Class I molecules. Synonyms: ERAP1 inhibitor compound 3; 4-Methoxy-3-(N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid. Grade: 99%. CAS No. 865273-97-8. Molecular formula: C20H21F3N2O5S. Mole weight: 458.45.
Evexomostat
Evexomostat is a methionine aminopeptidase 2 (MetAP2) inhibitor. Synonyms: poly({N-[(2RS)-2-hydroxypropyl]methacrylamide}-co-[N-methacryloylgly-cyl-L-phenylalanyl-L-leucyl-N1-(trans-4-{[({(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]-octan-6-yl}oxy)carbonyl]amino}cyclohexyl)glycinamide (~0.91:0.09 x)]); poly([N-(2-hydroxypropyl)methacrylamide]-co-{methacryloyl-Gly-Phe-Leu-Gly amide with O-[(trans-4-aminocyclohexyl)carbamoyl]fumagillol}). CAS No. 2416263-67-5. Molecular formula: [(C7H13NO2)n(C46H68N6O10)]m.
Firibastat
Firibastat (QGC001), an orally active brain penetrating proagent of EC33, is a first-in-class brain aminopeptidase A (APA) inhibitor ( K i =200 nM). Firibastat selectively and specifically inhibits conversion of brain angiotensin-II into angiotensin-III and decreases blood pressure in hypertensive rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QGC001; RB150. CAS No. 648927-86-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109058.
Fumagillin
Fumagillin is a compound isolated from the fungus Aspergillus fumigatus. Fumagillin is an antimicrobial agent used in the treatment of microsporidiosis. Fumagillin shows promise as both an an anti-infective and antiangiogenic agent. Group: Biochemicals. Alternative Names: Methionine aminopeptidase-2 Inhibitor; (2E,4E,6E,8E)-Mono[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3- (3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl] 2,4,6,8- decatetraenedioic acid ester. Grades: Highly Purified. CAS No. 23110-15-8. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C26H34O7, Molecular Weight: 458.54. US Biological Life Sciences.
Worldwide
gamma-L-Glutamic acid 7-amido-4-methylcoumarin
L-Glutamic acid γ-(7-amido-4-methylcoumarin) is a substrate for aminopeptidase or the assay of γ-glutamyl transferase producing a blue fluorescent solution upon cleavage. Synonyms: H-GLU(AMC)-OH; L-Glutamic Acid Gamma-(7-Amido-4-Methylcoumarin). Grade: 98%. CAS No. 72669-53-5. Molecular formula: C15H16N2O5. Mole weight: 304.30.
glutamate carboxypeptidase II
A metallo-carboxypeptidase that is predominantly expressed as a membrane-bound enzyme of 94-100 kDa, but also exists in a soluble form. Hydrolyses α-peptide bonds in Ac-Asp-Glu, Asp-Glu, and Glu-Glu, but also γ-glutamyl bonds in γ-Glu-Glu, and folylpoly-γ-glutamates. With folylpoly-γ-glutamates, shows processive carboxypeptidase activity to produce pteroylmonoglutamate. Does not hydrolyse Ac-β-Asp-Glu. Known inhibitors: quisqualic acid, Ac-β-Asp-Glu, and 2-phosphonomethyl-pentanedioate. In peptidase family M28 of Vibrio leucyl aminopeptidase. The release of C-terminal glutamate from folylpoly-γ-glutamates is also catalysed by EC 3.4.17.11 (glutamate carboxypeptidase) and EC 3.4.19.9 (γ-Glu-X carboxypeptidase). Group: Enzymes. Synonyms: N-acetylated-γ-linked-acidic dipeptidase (NAALADas. Enzyme Commission Number: EC 3.4.17.21. CAS No. 9074-87-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4074; glutamate carboxypeptidase II; EC 3.4.17.21; 9074-87-7; N-acetylated-γ-linked-acidic dipeptidase (NAALADase); folate hydrolase; prostate-specific membrane antigen; pteroylpoly-γ-glutamate carboxypeptidase; microsomal γ-glutamyl carboxypeptidase; pteroylpolyglutamate hydrolase; folylpolyglutamate h
glutamyl aminopeptidase
Ca2+-activated and generally membrane-bound. A zinc-metallopeptidase in family M1 (membrane alanyl aminopeptidase family). Group: Enzymes. Synonyms: aminopeptidase A; aspartate aminopeptidase; angiotensinase A; glutamyl peptidase; Ca2+-activated glutamate aminopeptidase; membrane aminopeptidase II; antigen BP-1/6C3 of mouse B lymphocytes; L-aspartate aminopeptidase; angiotensinase A2. Enzyme Commission Number: EC 3.4.11.7. CAS No. 9074-83-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4028; glutamyl aminopeptidase; EC 3.4.11.7; 9074-83-3; aminopeptidase A; aspartate aminopeptidase; angiotensinase A; glutamyl peptidase; Ca2+-activated glutamate aminopeptidase; membrane aminopeptidase II; antigen BP-1/6C3 of mouse B lymphocytes; L-aspartate aminopeptidase; angiotensinase A2. Cat No: EXWM-4028.
Glycine 4-nitroanilide
A substrate for glycine aminopeptidase. Synonyms: Gly-pNAN'-p-Nitrophenylglycinamide; 2-amino-N-(4-nitrophenyl)acetamide; Glycine p-nitroanilide. Grade: ≥ 99% (Assay by titration, HPLC, TLC). CAS No. 1205-88-5. Molecular formula: C8H9N3O3. Mole weight: 195.18.
Substrate for aminopeptidases. Synonyms: Glycyl-L-leucine; N-Glycyl-L-leucine. Grade: ≥ 98.5% (HPLC). CAS No. 869-19-2. Molecular formula: C8H16N2O3. Mole weight: 188.23.
Gly-Phe-pNA
Substrate for dipeptidyl aminopeptidase I (cathepsin C). Synonyms: Glycyl-L-phenylalanine p-nitroanilide. Grade: ≥ 99% (TLC). CAS No. 21027-72-5. Molecular formula: C17H18N4O4. Mole weight: 342.35.
Gly-Pro 4-methoxy-beta-naphthylamide
Gly-Pro 4-methoxy-beta-naphthylamide is a specific substrate for dipeptidyl aminopeptidase IV. Synonyms: H-Gly-Pro-4MbNA; glycyl-N-(4-methoxynaphthalen-2-yl)-L-prolinamide. Grade: 95%. CAS No. 42761-76-2. Molecular formula: C18H21N3O3. Mole weight: 327.38.
Gly-Pro-pNA TosOH
Very good substrate for the assay of dipeptidyl amino-peptidase IV (X-prolyldipeptidyl aminopeptidase), especially in normal and pathological human sera. Synonyms: Glycyl-L-proline 4-nitroanilide 4-toluenesulfonate. Grade: ≥ 99% (TLC, HPLC). CAS No. 65096-46-0. Molecular formula: C13H16N4O4·C7H8O3S. Mole weight: 464.50.
H-Ala-AFC
H-Ala-AFC is the fluorogenic substrate for microsomal alanine aminopeptidase, excitation at 400 nm, emission at 505 nm. Synonyms: (S)-2-amino-N-(2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)propanamide. Grade: 95%. CAS No. 126910-31-4. Molecular formula: C13H11F3N2O3. Mole weight: 300.24.
H-Ala-Ala-betaNA
H-Ala-Ala-betaNA is a substrate for dipeptidyl aminopeptidase I (cathepsin C). Synonyms: L-alanyl-L-alanine 2-naphthylamide; Ala-Ala 2-naphthylamide; L-Ala-L-Ala 2-naphthylamide. Grade: >99%. CAS No. 20724-07-6. Molecular formula: C16H19N3O2. Mole weight: 285.34.
H-Ala-Ala-Pro-pNA. HCl
H-Ala-Ala-Pro-pNA is a chromogenic substrate for dipeptidyl aminopeptidase yscV. Synonyms: H-ALA-ALA-PRO-PNA HCL. Grade: 95%. CAS No. 201732-27-6. Molecular formula: C17H24ClN5O5. Mole weight: 413.86.
H-Ala-Phe-Pro-pNA
H-Ala-Phe-Pro-pNA is a substrate for prolyl tripeptidyl aminopeptidases from the periodontal pathogens Porphyromonas gingivalis and Prevotella nigrescens. Synonyms: AFP-pNA. Grade: 95%. CAS No. 201732-35-6. Molecular formula: C23H27N5O5. Mole weight: 453.49.
H-Ala-Pro-pNA
H-Ala-Pro-pNA is an excellent substrate for the assay of dipeptidyl aminopeptidase IV (DPP IV). Synonyms: APPNA; Alanylproline-4-nitroanilide; L-Prolinamide, L-alanyl-N-(4-nitrophenyl)-. CAS No. 60189-44-8. Molecular formula: C14H18N4O4. Mole weight: 306.32.
H-D-Ala-D-Ala-D-Ala-D-Ala-OH
It is a substrate for D-aminopeptidase from Ochrobactrum anthropi. Synonyms: N-[2-((2-[(2-Aminopropanoyl)amino]propanoyl)amino)propanoyl]alanine; L-Alanine, N-[N-(N-L-alanyl-L-alanyl)-L-alanyl]-; (2-Isopropyl-1H-benzimidazol-1-yl)aceticacid. Grade: 95%. CAS No. 926-78-3. Molecular formula: C12H22N4O5. Mole weight: 302.33.
HFI 142
HFI 142 is an insulin-regulated aminopeptidase (IRAP) inhibitor (Ki = 2.01 μM). HFI 142 improves memory in control and memory-deficient mice models. Synonyms: HFI-142; HFI 142; HFI142; Ethyl 2-amino-7-hydroxy-4-(3-pyridinyl)-4H-1-benzopyran-3-carboxylate; 2-Amino-7-hydroxy-4-pyridin-3-yl-4H-chromene-3-carboxylic acid ethyl ester. Grade: ≥98% by HPLC. CAS No. 332164-34-8. Molecular formula: C17H16N2O4. Mole weight: 312.32.
H-Glu-AMC
H-Glu-AMC is a fluorogenic substrate for aminopeptidase a, producing a blue fluorescent solution upon cleavage. Synonyms: Glu-NH-med; (S)-4-Amino-5-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-5-oxopentanoic acid; (4S)-4-amino-5-[(4-methyl-2-oxochromen-7-yl)amino]-5-oxopentanoic acid; 7-(alpha-Glutamyl)-4-methylcoumarylamide; alpha-Glutamyl-7-amino-4-methylcoumarylamide; L-Glutamic acid alpha-(7-amido-4-methylcoumarin). Grade: ≥ 95%. CAS No. 98516-76-8. Molecular formula: C15H16N2O5. Mole weight: 304.30.
H-Gly-Phe-AMC
H-Gly-Phe-AMC is a sensitive substrate for dipeptidyl aminopeptidase I (cathepsin C). Synonyms: H-Gly-Phe-NHMec; L-Phenylalaninamide, glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; Glycyl-L-phenylalanine 7-amido-4-methylcoumarin. CAS No. 201852-70-2. Molecular formula: C21H21N3O4. Mole weight: 379.41.
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