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| Product | Description | |
|---|---|---|
| Amyl Acetate | Amyl Acetate (Normal). CAS No. 628-63-7. FEMA No. 2055. Kosher: Y. VIGON Item # 502289. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| Amyl Acetate Iso FCC | Amyl Acetate Iso FCC (Mixed Isomers 65/35). CAS No. ISOMER MIXTURE. Kosher: Y. VIGON Item # 500975. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Amyl Acetate Primary FCC | Amyl Acetate Primary FCC (Mixed Isomers 35/65). CAS No. ISOMER MIXTURE. Kosher: Y. VIGON Item # 500790. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Amyl acetates | Our wide distribution network, with locations coast-to-coast, helps guarantee fast, reliable service to Univar's customers. |  |
| 7-Methoxycoumarin-4-acetyl-[Asn670, Leu671]-Amyloid ?/A4 Precursor Protein 770 Fragment 669-674-(2,4-dinitrophenyl)Lys trifluoroacetate salt | ?96% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Amyl Acetoacetate | Amyl Acetoacetate. Group: Biochemicals. Alternative Names: Acetoacetic Acid Amyl Ester; Acetoacetic Acid Pentyl Ester; Pentyl Acetoacetate. Grades: Highly Purified. CAS No. 6624-84-6. Pack Sizes: 100g, 250g, 500g. US Biological Life Sciences. |  Worldwide |
| ?-Amylcinnamyl acetate | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Amylin, amide, rat acetate | Amylin, amide, rat acetate is a potent and high-affinity ligand for the AMY1 and AMY3 receptors and variably of AMY2 receptors. Synonyms: H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2.CH3CO2H (Disulfide bridge: Cys2-Cys7); L-lysyl-L-cysteinyl-L-asparagyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-arginyl-L-seryl-L-seryl-L-asparagyl-L-asparagyl-L-leucyl-glycyl-L-prolyl-L-valyl-L-leucyl-L-prolyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide (2->7)-disulfide acetic acid; Amylin (rat) acetate; Rat amylin acetate; Rat amylin amide acetate; Rat islet amyloid polypeptide acetate. Grade: ≥95%. Molecular formula: C169H276N52O55S2. Mole weight: 3980.45. |  |
| Amyloid β-Protein 10-20 acetate | Amyloid β-Protein (10-20) acetate is a fragment of Amyloid β peptide that may be used in the study of neurological diseases. Synonyms: H-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-OH.CH3CO2H; L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanine acetic acid. Grade: ≥95%. Molecular formula: C73H103N17O18. Mole weight: 1506.65. | |
| Amylostatin XG Octaacetate | Amylostatin XG Octaacetate is a protected intermediate of Amylostatin XG, an analogue of an α-glucosidase inhibitor, Acarbose. Synonyms: [1S-(1α,4α,5β,6α)]-4-O-[2,3-Di-O-acetyl-4,6-dideoxy-4-[[4,5,6-tris(acetyloxy)-3-[(acetyloxy)methyl]-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl]-D-glucopyranose; D-Glucopyranose, 4-O-[2,3-di-O-acetyl-4,6-dideoxy-4-[[4,5,6-tris(acetyloxy)-3-[(acetyloxy)methyl]-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl]-, 1,2,3,6-tetraacetate, [1S-(1α,4α,5β,6α)]-. CAS No. 85747-82-6. Molecular formula: C39H53NO23. Mole weight: 903.83. | |
| β-amyloid 1-11 acetate | β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide found in plaques associated with Alzheimer's disease. Synonyms: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-OH.CH3CO2H; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-glutamic acid acetic acid; b-amyloid 1-11 acetate. Grade: ≥95%. Molecular formula: C58H80N16O24. Mole weight: 1385.37. | |
| β-Amyloid 15-21 acetate | β-amyloid (15-21) acetate is a fragment of Amyloid-β peptide that may be used in the study of neurological diseases. It is found in plaques associated with Alzheimer's disease. Synonyms: b-Amyloid 15-21 acetate; Beta-Amyloid (15-21) acetate; H-Gln-Lys-Leu-Val-Phe-Phe-Ala-OH.CH3CO2H; L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanine acetic acid. Grade: ≥95%. CAS No. 2703745-43-9. Molecular formula: C45H69N9O11. Mole weight: 912.08. | |
| n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Primary Amyl Acetate | Primary Amyl Acetate. Synonyms: PAA. CAS: 628-63-7. Packing: Metal Drums. |  New Jersey NJ |
| 2'-O-(tert-Butyldimethylsilyl)-6α-hydroxy 7-epi-Paclitaxel | 2'-O-(tert-Butyldimethylsilyl)-6α-hydroxy 7-epi-Paclitaxel is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Uses: 6α-hydroxypaclitaxel derivative. Synonyms: (3xi,5beta,6alpha,7alpha,10beta,13alpha)-4,10-Bis(acetyloxy)-13-{[(2R,3S)-3-benzamido-2-{[tert-butyl(dimethyl)silyl]oxy}-3-phenylpropanoyl]oxy}-1,6,7-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate; 2-tert-Pentylcyclopentanon; 2-(1,1-dimethyl-propyl)-cyclopentan-1-one; 2'-NOR THIAMINE; 2-t-Amyl-cyclopentanon; (2aR,3S,4S,4aS,6S,9S,11S,12S,12aR,12bS)-9-(((2R,3S)-3-benzamido-2-((tert-butyldimethylsilyl)oxy)-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-3,4,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-d3,4]benzo[1,2-b]oxete-6,12b-diyl diacetate. Grade: > 98%. CAS No. 165065-08-7. Molecular formula: C53H65NO15Si. Mole weight: 984.16. | |
| 3-Pentyl Acetoacetate | 3-Pentyl Acetoacetate. Group: Biochemicals. Alternative Names: Acetoacetic Acid 3-Amyl Ester; Acetoacetic Acid 3-Pentyl Ester; 3-Amyl Acetoacetate. Grades: Highly Purified. CAS No. 13562-81-7. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| AC 187 acetate | AC 187 acetate is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels, and increases food intake in vivo. Synonyms: Ac-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2.CH3CO2H; N-acetyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide acetic acid. Grade: ≥95%. Molecular formula: C129H209N37O42. Mole weight: 2950.26. | |
| Amyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside | Amyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is an extensively employed compound in the realm of biomedicine, manifesting as an invaluable asset for the scrutiny of glycosylation mechanisms and the pioneering of groundbreaking pharmaceuticals. Synonyms: beta-D-Glucopyranoside, pentyl 2-(acetylamino)-2-deoxy-, 3,4,6-triacetate. CAS No. 146288-30-4. Molecular formula: C19H31NO9. Mole weight: 417.45. | |
| Beta-Sheet Breaker Peptide iAβ5 acetate | Beta-Sheet Breaker Peptide iAβ5 acetate inhibits amyloid formation in rat brain models. Synonyms: Beta-Sheet Breaker Peptide iA(c)micro5 Acetate; H-Leu-Pro-Phe-Phe-Asp-OH.CH3CO2H; L-leucyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-aspartic acid acetic acid; LPFFD.CH3CO2H; Acetic acid, compd. with (L-leucyl-yl-L-phenylalanyl-yl-L-prolyl-yl-L-phenylalanyl-yl)-L-Aspartate (1:1). Grade: ≥95%. CAS No. 2763585-09-5. Molecular formula: C35H47N5O10. Mole weight: 697.78. | |
| cAC 253 acetate | cAC 253 acetate is an antagonist of amylin, inhibiting 125I adrenomedullin binding with an IC50 value of 25 nM. Grade: >98.0%. Molecular formula: C128H206N42O42S2. Mole weight: 3069.39. | |
| Cagrilintide acetate | Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylase analogue. Cagrilintide acetate causes a reduction in food intake and significant weight loss in a dose-dependent manner. Cagrilintide acetate can be used in obesity studies[1][2][3]. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3462A. |  |
| DAPT | Cell permeable gamma-secretase inhibitor (IC50 = 115nM for total beta-amyloid, IC50 = 200nM for beta-amyloid 1-42). Reduces Abeta levels in vivo. Blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD). Does not inhibit persenilinase. Notch processing inhibitor. Enhances neuronal differentiation independent of sonic hedgehog (Shh) signaling. CDK5 activity inhibitor. Apoptosis enhancer. Group: Biochemicals. Alternative Names: (S)-Tert-butyl 2- ( (S) -2- (2- (3, 5-difluorophenyl) acetamido) propanamido) -2-phenylacetate; N-S-phenylglycine tert.butyl ester; GSI-IX; Secretase, gamma Inhibitor IX. Grades: Highly Purified. CAS No. 208255-80-5. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences. | Worldwide |
| Ethyl 2-pentylacetoacetate | Ethyl 2-pentylacetoacetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-N-AMYLACETOACETIC ACID ETHYL ESTER;2-AMYLACETOACETIC ACID ETHYL ESTER;2-ACETYLHEPTANOIC ACID ETHYL ESTER;ETHYL 2-AMYLACETOACETATE;ETHYL 2-ACETYLHEPTANOATE;2-acetyl-heptanoicaciethylester;amylacetoaceticacidethylester;Heptanoicacid,2-acetyl-,ethylester. Product Category: Heterocyclic Organic Compound. CAS No. 24317-94-0. Molecular formula: C11H20O3. Mole weight: 200.27. Purity: 0.96. IUPACName: ethyl 2-acetylheptanoate. Canonical SMILES: CCCCCC(C(=O)C)C(=O)OCC. Density: 0.948g/cm³. ECNumber: 246-157-0. Product ID: ACM24317940. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Isoeugenol acetate | Isoeugenol acetate (Acetyl isoeugenol), an essential oil constituent of nutmeg, clove, and cinnamon, shows excellent inhibitory effects against some metabolic enzymes such as acetylcholinesterase (AChE) enzymes ( IC 50 =77 nM; K i =16 nM), α-glycosidase ( IC 50 =19.25 nM; K i =21 nM), and α-amylase ( IC 50 =411.5 nM). Isoeugenol acetate is used medical and cosmetics industries for its antioxidant, anticancer, antimicrobial and anti-inflammatory properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Acetyl isoeugenol. CAS No. 93-29-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N6805. | |
| Native Human Cathepsin S | Cathepsin S is a lysosomal cysteine protease found primarily in the spleen and in lung macrophages. Its level is elevated in the brain tissue of those with Alzheimer's disease and Down syndrome. Cathepsin S may function in the processing of amyloid precursor protein to amyloid beta peptides. Applications: Cathepsin s from human spleen has been used in a study to assess the sequence identification, tissue distribution and polymorphism of the porcine cathepsin d (ctsd) gene. cathepsin s from human spleen has also been used in a study to investigate a new promising camptothecin analogue-polysaccharide conjugate. Group: Enzymes. Synonyms: CTSS; cathepsin S; EC 3.4.22.27; FLJ50259; MGC3886. Enzyme Commission Number: EC 3.4.22.27. CTSS. Storage: -70°C. Form: lyophilized powder. Lyophilized from 100 mM sodium acetate, pH 5.5, and 1 mM EDTA. Source: Human spleen. Species: Human. CTSS; cathepsin S; EC 3.4.22.27; FLJ50259; MGC3886. Cat No: NATE-0178. |  |
| Pentitol,1,5-anhydro-2,4-dideoxy-2-pentyl-,3-acetate | Pentitol,1,5-anhydro-2,4-dideoxy-2-pentyl-,3-acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-Amyl-4-acetoxytetrahydropyran;3-Pentyl-4-acetyl-oxytetrahydro-2H-pyran;jasmophyll;tetrahydro-3-pentyl-2h-pyran-4-oacetate;tetrahydro-3-pentyl-2h-pyran-4-olacetate;4-ACETOXY-3-PENTYLTETRAHYDROPYRAN;2H-PYRAN-4-OL, TETRAHYDRO-3-PENTYL:ACETATE;JASMOPYRANE. Product Category: Heterocyclic Organic Compound. Appearance: colourless clear liquid. CAS No. 18871-14-2. Molecular formula: C12H22O3. Mole weight: 214.3013. Purity: 0.96. IUPACName: (3-pentyloxan-4-yl) acetate. Canonical SMILES: CCCCCC1COCCC1OC(=O)C. Density: 0.97 g/cm³. ECNumber: 242-640-5. Product ID: ACM18871142. Alfa Chemistry ISO 9001:2015 Certified. | |
| Pentylcyclohexyl acetate | Pentylcyclohexyl acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: pentylcyclohexyl acetate;AMYLCYCLOHEXYLACETATE. Product Category: Heterocyclic Organic Compound. CAS No. 85665-91-4. Molecular formula: C13H24O2. Mole weight: 212.32846. Purity: 0.96. IUPACName: (1-pentylcyclohexyl) acetate. Canonical SMILES: CCCCCC1(CCCCC1)OC(=O)C. Density: 0.93g/cm³. ECNumber: 288-181-4. Product ID: ACM85665914. Alfa Chemistry ISO 9001:2015 Certified. Categories: Cyclohexanol. | |
| Petrelintide acetate | Perelintide (ZP8396) acetate is an amylin analog that shows potential for reducing body weight. Petrelintide can be used in diabetes research. Uses: Scientific research. Group: Peptides. Alternative Names: ZP8396 acetate. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10745A. | |
| PMX 205 acetate | PMX 205 acetate is a potent complement C5a receptor antagonist (IC50 = 31 nM). It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma. PMX 205 reduces fibrillar amyloid deposits, decreases hyperphosphorylated tau levels and rescues cognitive function in a mouse model of Alzheimer's Disease. Synonyms: hydrocinnamoyl-Orn(1)-Pro-D-Cha-Trp-Arg-(1).CH3CO2H; L-Arginine, N2-(1-oxo-3-phenylpropyl)-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-, (5→1)-lactam acetate; PMX205 acetate; PMX-205 acetate; Hydrocinnamate-(Orn-Pro-DCHA-Trp-Arg) acetate. Grade: ≥95%. Molecular formula: C47H66N10O8. Mole weight: 899.09. | |
| Pramlintide acetate | Pramlintide acetate is a polypeptide analogue of human amylin. Pramlintide acetate, an antidiabetic agent, is antineoplastic in colorectal cancer [1]. Uses: Scientific research. Group: Peptides. CAS No. 187887-46-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0058B. | |
| ReACp53 acetate | ReACp53 acetate is an acetate form of ReACp53 that is a cell-penetrating peptide, used to inhibit p53 amyloid formation in cancer cell lines. Grade: >98.0%. Molecular formula: C110H210N52O26. Mole weight: 2677.18. | |
| 2-Chloro-9H-fluorene | 2-Chloro-9H-fluorene acts as a reagent for the synthesis and the antibacterial functions of N-alkyl and N-amylamidinohydrazones of acetophanones, benzophenones and 2-acylfluorenes. Group: Biochemicals. Grades: Highly Purified. CAS No. 2523-44-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C13H9Cl, Molecular Weight: 200.66. US Biological Life Sciences. | Worldwide |
| 7-Methoxycoumarin-4-acetyl-[Asn670,Leu671]-Amyloid ?/A4 Precursor Protein 770 (667-676)-(2,4-dinitrophenyl)Lys-Arg-Arg Amide | ?96% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| 7-Methoxycoumarin-4-acetyl-[Asn670, Leu671]-Amyloid ?/A4 Precursor Protein 770 Fragment 667-674-(2,4-dinitrophenol)Dap | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| 7-Methoxycoumarin-4-acetyl-[Asn670, Leu671]-Amyloid ?/A4 Precursor Protein 770 Fragment 667-676-(2,4-dinitrophenyl)Lys-Arg-Arg amide | ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| a-Amyl cinnamic aldehyde diethyl acetal | a-Amyl cinnamic aldehyde diethyl acetal. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (2-(diethoxymethyl)-1-heptenyl)-benzen;(2-(diethoxymethyl)-1-heptenyl)benzene;[2-(diethoxymethyl)-1-heptenyl]-benzen;[2-(diethoxymethyl)-1-heptenyl]-Benzene;1,1-diethoxy-2-(phenylmethylene)-heptan;1,1-diethoxy-2-(phenylmethylene)heptane;1,1-diethoxy-2-am. Product Category: Heterocyclic Organic Compound. CAS No. 60763-41-9. Molecular formula: C18H28O2. Mole weight: 276.41. Product ID: ACM60763419. Alfa Chemistry ISO 9001:2015 Certified. Categories: D3K7R9235H. | |
| AC 187 | AC 187 is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels and increases food intake in vivo. Synonyms: Ac-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2; N-acetyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide; AC187; salmon calcitonin (8-32) reduced; acetyl-(Asn30,Tyr32)sCT(8-37); AC-187. Grade: >98%. CAS No. 151804-77-2. Molecular formula: C127H205N37O40. Mole weight: 2890.25. | |
| AC 253 | AC 253 is an amylin (AMY3) receptor antagonist. It inhibits andrenomedulin-stimulated cAMP production in vitro. Synonyms: L-Tyrosinamide, N-acetyl-L-leucylglycyl-L-arginyl-L-leucyl-L-seryl-L-glutaminyl-L-a-glutamyl-L-leucyl-L-histidyl-L-arginyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparaginyl-L-threonylglycyl-L-seryl-L-asparaginyl-L-threonyl-. Grade: ≥95%. CAS No. 151804-79-4. Molecular formula: C122H196N40O39. Mole weight: 2847.11. | |
| Acetyl-Amylin (8-37) (human) | Acetyl-Amylin (8-37) (human) is a most effective amylin antagonist, but its ability to block CGRP inhibition is limited. It completely reverses the inhibitory effect of IAPP on 14C-glycogen accumulation in vitro. Synonyms: Ac-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2; N-acetyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparagyl-L-asparagyl-L-phenylalanyl-glycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide. Grade: ≥95%. CAS No. 178603-79-7. Molecular formula: C140H218N42O46. Mole weight: 3225.53. | |
| Acetyl-Amylin (8-37) (rat) | Acetyl-Amylin (8-37) (rat). CAS No. 178603-82-2. Molecular formula: C142H229N43O44. Mole weight: 3242.6. | |
| Acetyl-Amyloid β-Protein (1-6) amide | Experiments using sub-peptides of Aβ42 show that the epitope identified by antibody A8 is located in the 1-6 region of Aβ. Synonyms: Ac-DAEFRH-NH2; L-Histidinamide, N-acetyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-; N-acetyl-L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidinamide. Grade: ≥95%. CAS No. 903883-22-7. Molecular formula: C35H50N12O11. Mole weight: 814.85. | |
| Acetyl-Amyloid ?-Protein Fragment 15-20 Amide | ?97% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| Acetyl-amyloid ss-protein(15-20)amide | Acetyl-amyloid ss-protein(15-20)amide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BETA-AMYLOID LIGAND;AMYLOID BETA-PROTEIN ACETYL-FRAGMENT 15-20 AMIDE;AC-QKLVFF;AC-AMYLOID BETA-PROTEIN (15-20) AMIDE;ACETYL-BETA-AMYLOID (15-20);ACETYL-AMYLOID BETA-PROTEIN (15-20) AMIDE;AC-GLN-LYS-LEU-VAL-PHE-PHE-NH2;AC-GLN-LYS-LEU-VAL-PHE-PHE-OH. Product Category: Heterocyclic Organic Compound. CAS No. 189064-06-0. Molecular formula: C42H62N8O9. Mole weight: 822.99. Purity: 0.96. IUPACName: (2S)-2-acetamido-N-[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]pentanediamide. Product ID: ACM189064060. Alfa Chemistry ISO 9001:2015 Certified. | |
| Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide | Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide is a membrane-permeable inhibitor of Aβ (1-40) fibrillogenesis. Synonyms: Ac-Lys-(NMe)Leu-Val-(NMe)Phe-Phe-NH2; N2-Acetyl-L-lysyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-phenylalanyl-L-phenylalaninamide; L-Phenylalaninamide, N2-acetyl-L-lysyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-phenylalanyl-. Grade: ≥95%. CAS No. 461640-33-5. Molecular formula: C39H59N7O6. Mole weight: 721.94. | |
| Acetyl-(Pro18,Asp21)-Amyloid β-Protein (17-21) amide | Acetyl-(Pro18,Asp21)-Amyloid β-Protein (17-21) amide is an analog of product H-4876 with small chemical modifications which enhance its stability against proteolytic degradation. It is a β-sheet breaker peptide that crosses the blood-brain barrier faster than most known proteins and peptides selectively absorbed by the brain, so it is assumed that the peptide is specifically transported to the brain. Synonyms: iAβ5p; Ac-LPFFD-NH2; N-acetyl-L-leucyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-isoasparagine; L-α-Asparagine, N-acetyl-L-leucyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-. Grade: ≥95%. CAS No. 339990-02-2. Molecular formula: C35H46N6O8. Mole weight: 678.78. | |
| ACID BLUE 41 | Acid blue 41 is a synthetic dye. It is a member of the triphenylmethane family of dyes and is known for its bright blue color. Uses: Acid blue 41 has several potential scientific research applications. one of the most promising uses is in the field of bioimaging. acid blue 41 has been shown to selectively stain mitochondria in live cells, making it a useful tool for studying mitochondrial function and dynamics. it has also been used as a fluorescent probe for detecting amyloid fibrils, which are associated with several neurodegenerative diseases. Additional or Alternative Names: LANAPERL BLUE B;CI 62130;ACID BLUE 41;ALIZARINE DIRECT BLUE ARA;ALIZARINE SAPPHIRE AR;10-dioxo-)-monosodiumsalt;10-dioxo-dihydro-monosodiumsalt;2-anthracenesulfonicacid,1-amino-9,10-dihydro-4-(p-(n-methylacetamido)anilino. Product Category: Acid Dyes. Appearance: Dark blue powder. CAS No. 2666-17-3. Molecular formula: C23H18N3NaO6S. Mole weight: 487.46. IUPACName: sodium;4-[4-[acetyl(methyl)amino]anilino]-1-amino-9,10-dioxoanthracene-2-sulfonate. Canonical SMILES: CC(=O)N(C)C1=CC=C(C=C1)NC2=CC(=C(C3=C2C(=O)C4=CC=CC=C4C3=O)N)S(=O)(=O)[O-].[Na+]. Density: 1.542 g/mL. ECNumber: 220-201-9. Product ID: ACM2666173. Alfa Chemistry ISO 9001:2015 Certified. Categories: Acid Blue 147. | |
| Amyl 2-acetamido-2-deoxy-b-D-glucopyranoside | Amyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a versatile biomedical compound, finding applications in the research of an array of ailments. Identified as N-acetylmuramic acid, this compound showcases notable antibacterial attributes, rendering it invaluable in the enzymatic assessment of bacterial muramidases. Crucially, it assumes an indispensable role in peptidoglycan research and development, a pivotal constituent of bacterial cell walls. Synonyms: N-((2R,3R,4R,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(pentyloxy)tetrahydro-2H-pyran-3-yl)acetamide. CAS No. 94483-64-4. Molecular formula: C13H25NO6. Mole weight: 291.34. | |
| ?-Amylcinnamaldehyde dimethyl acetal | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| AP2238 | AP2238 is a inhibitor of both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Uses: Cholinesterase inhibitors. Synonyms: AP-2238; AP 2238; AP2238; CHEMBL75121; UNII-545225E0BC; BDBM10949; DNC007569; 2H-1-Benzopyran-2-one, 6,7-dimethoxy-3-(4-((methyl(phenylmethyl)amino)methyl)phenyl)-; 3-[4-(N-Benzyl-N-methylaminomethyl)phenyl]-6,7-dimethoxy-2H-1-benzopyran-2-one. Grade: 98%. CAS No. 553681-56-4. Molecular formula: C26H25NO4. Mole weight: 415.48. | |
| bis(7)-Tacrine | Acetylcholinesterase (AChE) is the primary cholinesterase in the body. It is an enzyme catalyzing the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. Tacrine is an amino acridine compound that inhibits acetylcholinesterase (AChE), which has been proposed as a clinical treatment for Alzheimer's disease. Bis(7)-Tacrine is a tacrine dimer, linked via a 7-carbon alkyl spacer. It inhibits AChE with an IC50 of 0.40 nM, making it more than 1,000 times more potent than tacrine. It is thought to have multiple mechanisms of action including inhibition of AChE, and inihbititon of the amyloid precursor protein/beta-amyloid cascade. It has been shown to inhibit the formation of Aβ1-42 oligomers and reduce the amount of pre-formed Aβ1-42 oligomers. Synonyms: 1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydro-acridine. Grade: ≥98%. CAS No. 224445-12-9. Molecular formula: C33H40N4·2HCl. Mole weight: 565.6. | |
| CHF 5074 | CHF 5074 is a novel γ-secretase modulator. It reduces Aβ42 and Aβ40 secretion with IC50 values of 3.6 and 18.4 μM respectively. It protects SH-SY5Y human neuronal-like cells from amyloidbeta 25-35 and tumor necrosis factor related apoptosis inducing ligand toxicity in vitro. Uses: Chf5074 induces microglia alternative activation in plaque-free tg2576 mice and primary glial cultures exposed to beta-amyloid. it restores visual memory ability and pre-synaptic cortical acetylcholine release in pre-plaque tg2576 mice. it is a non-steroidal anti-inflammatory derivative holding disease-modifying potential for the treatment of alzheimer's disease. it significantly reduces the apoptosis in hippocampal neurons exposed to ogd, as revealed by cleaved-caspase-3 immunoreactivity and tunel staining. Synonyms: CHF-5074; Itanapraced; 1-[4-(3,4-dichlorophenyl)-3-fluorophenyl]cyclopropane-1-carboxylic acid. Grade: >98%. CAS No. 749269-83-8. Molecular formula: C16H11Cl2FO2. Mole weight: 325.16. | |
| [D-Phe12,Leu14]-Bombesin acetate | [D-Phe12,Leu14]-Bombesin is a bombesin receptor antagonist. It inhibits bombesin binding to rat brain (IC50 = 2 μM), inhibits amylase release in vitro (IC50 = 4 μM), and attenuates bombesin-mediated suppression of food intake in vivo. Molecular formula: C77H118N22O20. Mole weight: 1671.89. | |
| Eplontersen sodium | Eplontersen sodium the sodium salt form of Eplontersen (HY-148089). Eplontersen sodium is a triantennary N-acetyl galactosamine (GalNAc3-7a)-conjugated antisense oligonucleotide targeting transthyretin (TTR) mRNA to inhibit production of both variant and wild-type TTR protein. Misfolded TTR induces amyloid fibrils formation in the heart and peripheral nerves, leads to amyloid TTR (ATTR) amyloidosis diseases[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2131025-75-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148089A. | |
| Fustin | Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) is a potent amyloid β (Aβ) inhibitor. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases the expression of acetylcholine (ACh) levels, choline acetyltransferase (ChAT) activity, and ChAT gene induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) decreases in acetyl cholinesterase (AChE) activity and AChE gene expression induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases muscarinic M1 receptor gene expression and muscarinic M1 receptor binding activity. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) can be used for Alzheimer's disease research [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone. CAS No. 20725-03-5. Pack Sizes: 1 mg. Product ID: HY-N8376. | |
| Galantamine hydrobromide | Galantamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. It prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells. Uses: Nootropic agents. Synonyms: 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide (1:1), (4aS,6R,8aS)-; 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, monohydrobromide, (4aS,6R,8aS)-; Galanthamine, hydrobromide; (-)-Galantamine hydrobromide; (-)-Galanthamine hydrobromide; Galanthamine hydrogen bromide; Jilkon hydrobromide; Lycoremine hydrobromide; Nivalin; Nivaline; Nivaline (pharmaceutical); Razadyne; Reminyl; Tamilin. Grade: ≥95%. CAS No. 1953-4-4. Molecular formula: C17H21NO3.HBr. Mole weight: 368.28. | |
| Glycine,l-methionyl-L-Leucylglycyl-L-isoleucyl-L-isoleucyl-L-alanylglycyl-L-Lysyl-l-asparaginyl-l-seryl- | Glycine,l-methionyl-L-Leucylglycyl-L-isoleucyl-L-isoleucyl-L-alanylglycyl-L-Lysyl-l-asparaginyl-l-seryl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AMYLOID BETA-PROTEIN FRAGMENT 35-25;AMYLOID BETA-PROTEIN (35-25);MET-LEU-GLY-ILE-ILE-ALA-GLY-LYS-ASN-SER-GLY;H-MET-LEU-GLY-ILE-ILE-ALA-GLY-LYS-ASN-SER-GLY-OH;BETA-AMYLOID (35-25);MLGIIAGKNSG;AMYLOID B-PROTEIN, FRAGMENT 35-25;amyloid β-protein fragment 35. Product Category: Heterocyclic Organic Compound. CAS No. 147740-73-6. Molecular formula: C45H81N13O14S. Mole weight: 1060.27. Purity: 0.96. IUPACName: 2-[[2-[[4-amino-2-[[6-amino-2-[[2-[2-[[2-[[2-[[2-[[2-[(2-amino-4-methylsulfanylbutanoyl)amino]-4-methylpentanoyl]amino]acetyl]amino]-3-methylpentanoyl]amino]-3-methylpentanoyl]amino]propanoylamino]acetyl]amino]hexanoyl]amino]-4-oxobutanoyl]amino]-3-hydrox. Product ID: ACM147740736. Alfa Chemistry ISO 9001:2015 Certified. Categories: HY-P4740. | |
| ISRIB | ISRIB is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Synonyms: 2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide; 2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide; ISRIB compound; trans-ISRIB. CAS No. 1597403-47-8. Molecular formula: C22H24Cl2N2O4. Mole weight: 451.34. | |
| ISRIB (mix-Isomer) | ISRIB (mix-Isomer), is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Synonyms: Acetamide, N,?N'-1,?4-cyclohexanediylbis[2?-(4-chlorophenoxy)?- ISRIB compound. CAS No. 548470-11-7. Molecular formula: C22H24Cl2N2O4. Mole weight: 451.34. | |
| Ixazomib Citrate | The citrate salt form of Ixazomib which is a proteasome inhibitor. It is undergoing a rollover Phase II trial against multiple myeloma, amyloidosis and lymphoma in sorts of countries. IC50 = 3.4 nM. Synonyms: 4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid; MLN9708; MLN-9708; MLN 9708. Grade: 98%. CAS No. 1239908-20-3. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12. | |
| Lactoferrin (322-329) (human) | Lactoferrin (322-329) (human) is a highly amyloidogenic region of lactoferrin. Synonyms: H-Asn-Ala-Gly-Asp-Val-Ala-Phe-Val-OH; L-asparagyl-L-alanyl-glycyl-L-alpha-aspartyl-L-valyl-L-alanyl-L-phenylalanyl-L-valine; (2S,5S,8S,11S,14S)-5-benzyl-14-(2-((S)-2-((S)-2,4-diamino-4-oxobutanamido)propanamido)acetamido)-2,11-diisopropyl-8-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazahexadecane-1,16-dioic acid. Grade: ≥95%. CAS No. 496808-32-3. Molecular formula: C35H53N9O12. Mole weight: 791.86. | |
| L-Methionine,glycyl-L-seryl-L-asparaginyl-L-Lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-l-leucyl- | L-Methionine,glycyl-L-seryl-L-asparaginyl-L-Lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-l-leucyl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: A4559_SIGMA, MolPort-003-940-171, beta-AMYLOID, Fragment 25-35, Amyloid beta-Protein Fragment 25-35, CID3407255, CID 3407255, 131602-53-4. Product Category: Heterocyclic Organic Compound. CAS No. 131602-53-4. Molecular formula: C45H81N13O14S. Mole weight: 1060.26834. Purity: 0.96. IUPACName: 2-[[2-[[2-[[2-[[2-[2-[[2-[[6-amino-2-[[4-amino-2-[[2-[(2-aminoacetyl)amino]-3-hydroxypropanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]amino]acetyl]amino]propanoylamino]-3-methylpentanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4. Canonical SMILES: CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CN. Density: 1.249g/cm³. Product ID: ACM131602534. Alfa Chemistry ISO 9001:2015 Certified. Categories: GSNKGAIIGLM. | |
| Lysozyme, Positive Control (LZM, LYZ, Renal Amyloidosis, N-Acetylmuramide Glycanhydrolase, Muramidase) | Lysozyme, Positive Control (LZM, LYZ, Renal Amyloidosis, N-Acetylmuramide Glycanhydrolase, Muramidase). Group: Molecular Biology. Pack Sizes: 15ul. US Biological Life Sciences. | Worldwide |
| Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) | Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) is a pro-memapsin-2 fluorogenic substrate (FRET) containing the β-secretase site of the Swedish mutation of APP, SEVNLDAEF. Synonyms: Mca-(Asn670,Leu671)-APP770 (667-675)-Lys(Dnp); Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH; N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine; L-Lysine, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-. Grade: ≥95%. CAS No. 1802078-31-4. Molecular formula: C68H88N14O27. Mole weight: 1533.53. | |
| Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide | Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide is a fluorogenic (FRET) substrate for pro-memapsin-2 containing the β-secretase site of the Swedish mutation of APP. Its kinetic parameters at pH 4.5 are Km = 4.5 μM and kcat = 0.25 min-1. Synonyms: Mca-(Asn670,Leu671)-APP770 (667-675)-Lys(Dnp) amide; Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-NH2; N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysinamide; L-Lysinamide, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-; Mca-SEVNLDAEFK(Dnp) amide. Grade: ≥95%. CAS No. 1802078-32-5. Molecular formula: C68H89N15O26. Mole weight: 1532.54. | |
| Methyl tridecanoate | Methyl tridecanoate moderately inhibits β-amyloid aggregation. Methyl tridecanoate weakly inhibits acetylcholinesterase (AChE) [1]. Uses: Scientific research. Group: Natural products. CAS No. 1731-88-0. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W004287. | |
| p-Amyl acetophenone | p-Amyl acetophenone. Group: Liquid crystal (lc) building blocks. CAS No. 37593-02-5. Product ID: 1-(4-pentylphenyl)ethanone. Molecular formula: 190.28g/mol. Mole weight: C13H18O. CCCCCC1=CC=C(C=C1)C(=O)C. InChI=1S / C13H18O / c1-3-4-5-6-12-7-9-13 (10-8-12) 11 (2) 14 / h7-10H, 3-6H2, 1-2H3. KBKGPMDADJLBEM-UHFFFAOYSA-N. 96.0%(GC). |  |
| PP2A Activating Ligand, ITH12246 | A cell-permeable, relatively non-toxic, 1,8-naphthyridine derived compound that blocks the inhibitory effect of protein phosphatase inhibitors, such as okadaic acid, on protein phosphatase 2A (PP2A). Exhibits blood-brain barrier permeability. Protects neurons against beta-amyloid peptides (Ab1-42) toxicity and okadaic acid-induced tau hyperphosphorylation. Also protects against rotenone and oligomycin A induced neurotoxicity in SH-SY5Y neuroblastoma cells (at ~300nM). Prevents the development of glutamate-induced neuronal lesions in rat hippocampal slices by up-regulating PP2A (~3uM). Shown to reverse the scopolamine-induced memory loss in mice (~10mg/kg i.p) and significantly reduces the infarct volume in an animal model of stroke (~2.5mg/kg). Also acts as an inhibitor of acetylcholinesterase activity in Electrophorus electricus (IC50 = 60nM) and human erythrocytes (IC50 = 780nM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?·HCl. US Biological Life Sciences. | Worldwide |
| Pramlintide acetate hydrate | Pramlintide is an analog of amylin, an antidiabetic peptide hormone released into the bloodstream. It has been used in the treatment of diabetes. Grade: 98%. CAS No. 196078-30-5. Molecular formula: C173H273N51O56S2. Mole weight: 4027.46. | |
| trans-Chalcone | Trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity. Trans-Chalcone is a potent fatty acid synthase (FAS) and α-amylase inhibitor. Trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7. Synonyms: Chalcone; (E)-Chalcone; Benzalacetophenone; Benzylideneacetophenone; (2E)-1,3-diphenylprop-2-en-1-one. Grade: ≥97%. CAS No. 614-47-1. Molecular formula: C15H12O. Mole weight: 208.26. | |
| Trimesinic Acid | Trimesinic Acid is used for multifunctional therapeutics. It shows inhibitory activity against Torpedo Californica acetylcholinesterase and prevented amyloid- β peptide aggregate formation. Group: Biochemicals. Grades: Highly Purified. CAS No. 554-95-0. Pack Sizes: 5g, 25g. Molecular Formula: C9H6O6. US Biological Life Sciences. | Worldwide |
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