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| Product | Description | |
|---|---|---|
| (+/-)-Atenolol ( (±) -4- {2-Hydroxy-3- [ (1-methylethyl) amino] propoxy} benzeneacetamide, Beta1-Adrenergic Receptor Blocker, (±)-Atenolol, Beta1-Adrenergic Receptor Antagonist, (±)-Atenolol) | Selective beta-1 adrenergic blocking agent. An anti-hypertensive and anti-arrhythmic agent. Reported to diminish cerebrospinal fluid production. Group: Biochemicals. Grades: Highly Purified. CAS No. 29122-68-7. Pack Sizes: 1g. Molecular Formula: C??H??N?O?. US Biological Life Sciences. |  Worldwide |
| 1,5-Difluoro-2,4-dinitrobenzene | 1,5-Difluoro-2,4-dinitrobenzene acts as an oleanolic acid NO-releasing derivative used towards the treatment of colon cancer. Also used in the synthesis of beta blockers used as bronchodialators. Group: Biochemicals. Grades: Highly Purified. CAS No. 327-92-4. Pack Sizes: 1g, 10g. Molecular Formula: C6H2F2N2O4, Molecular Weight: 204.09. US Biological Life Sciences. | Worldwide |
| 4'-Hydroxyphenyl Carvedilol | 4'-Hydroxyphenyl carvedilol, as a metabolite of Carvedilol, is a nonselective beta blocker/alpha-1 blocker. Carvedilol is used in the treatment of hypertension. Synonyms: 4-Hydroxycarvedilol; 4'-Hydroxycarvedilol; BM 140686; BM 14686. Grade: > 95%. CAS No. 142227-49-4. Molecular formula: C19H19ClN2O. Mole weight: 422.47. |  |
| 4-(Methylsulfonamido)benzaldehyde | An impurity of Sotalol. Sotalol is a non-selective competitive beta-adrenergic receptor blocker that also exhibits Class III antiarrhythmic properties. Synonyms: N-(4-formylphenyl)methanesulfonamide; N-(4-formylphenyl)methanesulfonamide. Grade: 97 %. CAS No. 83922-54-7. Molecular formula: C8H9NO3S. Mole weight: 199.23. | |
| 7-Hydroxypropranolol-b-D-glucuronide | 7-Hydroxypropranolol-b-D-glucuronide is a metabolite derived from Propranolol, a non-selective beta blocker employed for the research of hypertension, angina and arrhythmias. By virtue of its pivotal role in deciphering the perplexing pharmacokinetics of propranolol and unraveling potential drug-drug interactions, this exceptional compound stands as an indispensable asset in the realm of pharmaceutical sciences. Molecular formula: C22H29NO9. Mole weight: 451.47. | |
| 7'-Hydroxypropranolol-b-D-glucuronide | 7'-Hydroxypropranolol-b-D-glucuronide, a fundamental compound in the field of biomedicine, holds immense significance. As the metabolite of Propranolol, a beta-blocker extensively employed in hypertension, angina, and arrhythmia management, this glucuronide derivative plays a pivotal role in unraveling the pharmacokinetics and metabolism of Propranolol. Such insights greatly facilitate the formulation of secure and efficacious treatment approaches. Molecular formula: C22H29NO9. Mole weight: 451.47. | |
| A-53930 A | A-53930 A is a Ca2+ channel blocker produced by Streptomyces vinaceusdrappus SANK 62394. It selectively blocks the activity of N-type Ca2+ channels, but does not inhibit L-type Ca2+ channels. It has weak activity against Gram-negative bacteria. Synonyms: 4H-Imidazo(4,5-c)pyridin-4-one, 1,3a,5,6,7,7a-hexahydro-2-((2-((3-amino-6-(((3S)-3-amino-6-(((3S)-3-amino-6-(((3S)-3,6-diamino-1-oxohexyl)amino)-1-oxohexyl)amino)-1-oxohexyl)amino)-1-oxohexyl)amino)-6-O-(aminocarbonyl)-2-deoxy-beta-D-gulopyranosyl)amino)-7-hydroxy-, (3aS,7R,7aS)-. CAS No. 182410-79-3. Molecular formula: C37H70N14O11. Mole weight: 887.04. | |
| A-53930 B | A-53930 B is a Ca2+ channel blocker produced by Streptomyces vinaceusdrappus SANK 62394. It selectively blocks the activity of N-type Ca2+ channels, but does not inhibit L-type Ca2+ channels. It has weak activity against Gram-negative bacteria. Synonyms: 4H-Imidazo(4,5-c)pyridin-4-one, 1,3a,5,6,7,7a-hexahydro-2-((6-O-(aminocarbonyl)-2-deoxy-2-(((3S,10S,17S,24S,31S)-3,10,17,24,31,34-hexamino-1,8,15,22,29-pentaoxo-7,14,21,28-tetraazatetratriacont-1-yl)amino)-beta-D-gulopyranosyl)amino)-7-hydroxy-, (3aS,7R,7aS)-. CAS No. 182697-76-3. Molecular formula: C43H82N16O12. Mole weight: 1015.21. | |
| Alprenolol hydrochloride | Alprenolol hydrochloride is the hydrochloride salt of alprenolol, which is a non-selective 5-HT1A receptor antagonist and beta blocker. It is used in the treatment of angina pectoris. It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically. Uses: Adrenergic beta-antagonists. Synonyms: 1-[(1-Methylethyl)amino]-3-[2-(2-propen-1-yl)phenoxy]-2-propanol Hydrochloride; 1-(o-Allylphenoxy)-3-(isopropylamino)-2-Propanol Hydrochloride; 1-[(1-Methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-2-propanol Hydrochloride; (±)-1-(o-Allylphenoxy)-3-isopropylamino-2-propanol Hydrochloride; (±)-Alprenolol Hydrochloride; 1-(2-Allylphenoxy)-2-hydroxy-3-isopropylaminopropane Hydrochloride; Alfeprol; DL-1-(o-Allylphenoxy)-3-isopropylamino-2-propanol Hydrochloride; Dimacor; Gubernal; dl-Alprenolol Chloride. Grade: ≥99% by HPLC. CAS No. 13707-88-5. Molecular formula: C15H24NO2Cl. Mole weight: 285.81. | |
| Ancarolol | Ancarolol is a beta-adrenergic blocker. Synonyms: (R,S)-2'-(3-(tert-Butylamino)-2-hydroxypropoxy-2-furanilid. Grade: 95%. CAS No. 75748-50-4. Molecular formula: C18H24N2O4. Mole weight: 332.39. | |
| Arotinolol | Arotinolol is a medication used primarily for the treatment of hypertension and certain types of arrhythmias. Arotinolol is a non-selective beta-adrenergic receptor antagonist (beta-blocker) that blocks both beta-1 and beta-2 receptors. This action reduces the effects of adrenaline and noradrenaline, leading to a decrease in heart rate and blood pressure. In addition to its beta-blocking properties, arotinolol also exhibits alpha-1 adrenergic receptor antagonism. This action leads to vasodilation and further reduction in blood pressure. Arotinolol is used to treat high blood pressure, helping to prevent complications such as stroke, heart attack, and kidney problems. It can be used to manage certain types of cardiac arrhythmias (irregular heartbeats). Arotinolol may be used to alleviate symptoms of angina, a condition characterized by chest pain due to reduced blood flow to the heart. Synonyms: 2-Thiophenecarboxamide, 5-[2-[[3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl]thio]-4-thiazolyl]-; 2-Thiophenecarboxamide, 5-[2-[[3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl]thio]-4-thiazolyl]-, (±)-; 5-[2-[[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropyl]thio]-4-thiazolyl]-2-thiophenecarboxamide; (±)-Arotinolol; 2-(3-tert-Butylamino-2-hydroxypropylthio)-4-(5-carbamoyl-2-thienyl)thiazole; NSC 317940. Grade: ≥95%. CAS No. 68377-92-4. Molecular formula: C15H21N3O2S3. Mole weight: 371.54. | |
| Atenolol beta-D-Glucuronide | Atenolol beta-D-Glucuronide is an impurity of Atenolol, which is a cardioselective β-adrenergic blocker. Synonyms: Atenolol β-D-Glucuronide; (R,S)-Atenolol O-β-D-glucuronide. CAS No. 889359-84-6. Molecular formula: C20H30N2O9. Mole weight: 442.47. | |
| Betaxolol | Betaxolol is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma. Uses: Scientific research. Group: Signaling pathways. CAS No. 63659-18-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0381. |  |
| (±)-Betaxolol-[d7] hydrochloride | (±)-Betaxolol-[d7] hydrochloride is the labelled salt of (±)-Betaxolol, which is a cardioselective β1-adrenergic blocker and could be used as an antihypertensive agent. Synonyms: Betaxolol-d7 hydrochloride; (±)-Betaxolol-d7 HCl (iso-propyl-d7); 2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[[1-(methyl-d3)ethyl-1,2,2,2-d4]amino]-, hydrochloride (1:1). Grade: 95% by HPLC; 98% atom D. CAS No. 1219802-92-2. Molecular formula: C18H23D7ClNO3. Mole weight: 350.94. | |
| Betaxolol hydrochloride | Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SL75212. CAS No. 63659-19-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0381A. | |
| Betaxolol hydrochloride | Betaxolol is a β1 adrenergic receptor blocker with IC50 of 6 μM. Uses: Antihypertensive agents. Synonyms: BAY K 5552; BAY K5552; BAY K-5552; BAY-K-5552; BAYK5552; Betaxolol Hydrochloride; Betaxolol HCL; Betoptima; Kerlone; Betoptic; Kerlon; ALO 140102; ALO-1401-02; ALO140102. Grade: >98%. CAS No. 63659-19-8. Molecular formula: C18H29NO3·HCl. Mole weight: 343.89. | |
| Bevantolol Hydrochloride | Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. Synonyms: 2-Propanol,1-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-3-(3-methylphenoxy)-,hydrochloride; 1-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-methylphenoxy)-2-propanol Hydrochloride. Grade: ≥95%. CAS No. 42864-78-8. Molecular formula: C20H28ClNO4. Mole weight: 381.89. | |
| Bisoprolol hemifumarate | Bisoprolol is a beta-adrenoceptor blocking drug (beta-blocker). More specifically, it is a selective type β1 adrenergic receptor blocker. Uses: Antihypertensive agents. Synonyms: 1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol hemifumarate; Bisoprolol Fumarate; Concor; Detensiel; Emcor; Euradial; Isoten; Monocor; Soprol; Zebeta; Fondril; (+/-)-Bisoprolol hemifumarate; 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (2E)-2-butenedioate (2:1); 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (E)-2-butenedioate (2:1) (salt); 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (±)-, (E)-2-butenedioate (2:1) (salt); 1-(4-((2-Isopropoxyethoxy)methyl)phenoxy)-3-(isopropylamino)propan-2-ol hemifumarate; EMD 33512; Emvoncor; Maintate. Grade: >98%. CAS No. 104344-23-2. Molecular formula: C18H31NO4.1/2(C4H4O4). Mole weight: 383.48. | |
| Bucindolol | Bucindolol is a third-generation, non-selective β-adrenergic receptor blocker that acts on both β1 and β2 receptors. Ki values are 1.61, 1.20 and 68.9 nM for β1-, β2- and α1-adrenoceptors respectively. Bucindolol is a high-affinity, competitive beta blocker used in the treatment of congestive heart failure and hypertension. It also displays vasodilatory and antihypertensive actions. Synonyms: Benzonitrile, 2-[2-hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]-; 2-[2-Hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]benzonitrile; DL-Bucindolol; MJ 13105-1; o-(2-Hydroxy-3-((2-indol-3-yl-1,1-dimethylethyl)amino)propoxy)benzonitrile; 2-(3-((1-(1H-indol-3-yl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)benzonitrile. Grade: ≥98%. CAS No. 71119-11-4. Molecular formula: C22H25N3O2. Mole weight: 363.45. | |
| Bucindolol hydrochloride | Bucindolol is a third-generation, non-selective β-adrenergic receptor blocker used in the treatment of congestive heart failure and hypertension. Uses: Adrenergic beta-antagonists. Synonyms: Benzonitrile, 2-[2-hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]-, hydrochloride (1:1); Benzonitrile, 2-[2-hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]-, monohydrochloride; DL-Bucindolol hydrochloride; o-(2-Hydroxy-3-((2-indol-3-yl-1,1-dimethylethyl)amino)propoxy)benzonitrile monohydrochloride; 2-(3-((1-(1H-indol-3-yl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)benzonitrile hydrochloride. Grade: ≥95%. CAS No. 70369-47-0. Molecular formula: C22H25N3O2.HCl. Mole weight: 399.91. | |
| Bufuralol hydrochloride | Bufuralol (Ro-34787) is a β-adrenoceptor blocker with partial peripheral vasodilating activity and is potentially useful for the treatment of hypertension. It is primarily metabolized by cytochrome P450 (CYP) isoform CYP2D6, with CYP1A2 and CYP2C19 also contributing to 1'-hydroxylation. Most beta blockers are aryloxypropanolamine-based, in this rare exception, the benzofuran oxygen is part of a ring instead of derived from the epichlorohydrin precursor. Synonyms: Ro 3-4787. Grade: ≥95%. CAS No. 60398-91-6. Molecular formula: C16H23NO2·HCl. Mole weight: 297.8. | |
| CaCC Blocker IV, Benzbromarone (CaCC Blocker IV, Calcium-Activated Chloride Channel Blocker IV, TMEM16 Blocker IV, (3,5-dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)methanone, ANO Blocker IV, Anoctamin Blocker IV, BBR) | A cell-permeable uricosuric agent that, in addition to its known efficacy in gout treatment, acts as a reversible CaCC blocker and is reported to be more potent than NFA and NPPB in suppressing 500nM Ionomycin- induced I- influx in TMEM16A-expressing HEK293 cells (IC50 = 9.97, 140, and 150uM, respectively) as well as in blocking voltage-gated Cl- current in TMEM16B-expressing HEK293 cells, while exhibiting much reduced potency against ENaC (alpha, beta, and gamma) or CFTR. Shown to significantly reduce mucin secretion from NHBE (normal human bronchial epithelial) and suppress human ASM (airway smooth muscle) contraction upon muscarinic receptor stimulation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. Molecular Formula: C??H??Br?O?. US Biological Life Sciences. | Worldwide |
| Carteolol hydrochloride | Carteolol hydrochloride (OPC-1085 hydrochloride) is a non-selective beta blocker used to treat glaucoma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-1085 hydrochloride. CAS No. 51781-21-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17495A. | |
| Carvedilol EP impurity E | Carvedilol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins). Carvedilol is used to treat heart failure and hypertension (high blood pressure). It is also used after a heart attack that has caused your heart not to pump as well. Carvedilol is a nonselective beta blocker/alpha-1 blocker and used in management of congestive heart failure (CHF). Carvedilol EP impurity E is an impurity of Carvedilol. Synonyms: Carvedilol Impurity E; Carvedilol USP E. Grade: ≥95%. CAS No. 64464-07-9. Molecular formula: C9H14ClNO2. Mole weight: 203.67. | |
| Carvedilol Phosphate | Carvedilol phosphate hemihydrate is a nonselective beta (β1, β2) blocker and alpha (α1) blocker, inhibits LDL oxidation (IC50 = 3.8 μM). Uses: Nonselective beta (β1, β2) blocker and alpha (α1) blocker. Synonyms: 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol; phosphoric acid; hydrate. Grade: ≥98%. CAS No. 610309-89-2. Molecular formula: C24H26N2O4·H2O·H3O4P. Mole weight: 522.488. | |
| Deoxysotalol hydrochloride | An impurity of Sotalol. Sotalol is a non-selective competitive beta-adrenergic receptor blocker that also exhibits Class III antiarrhythmic properties. Synonyms: Sotalol EP Impurity A Hydrochloride; Sotalol USP Related Comopound C; Deshydroxy Sotalol Hydrochloride; N-(4-(2-((1-Methylethyl)amino)ethyl)phenyl)methanesulfonamide monohydrochloride. Grade: ≥95%. CAS No. 16974-44-0. Molecular formula: C12H21ClN2O2S. Mole weight: 292.83. | |
| Esmolol-d7 Acid Sodium Salt | One of the isotope labelled form of Esmolol Acid Sodium Salt, which is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages. Synonyms: 4-[2-Hydroxy-3-[(1-methylethyl-)amino]propoxy]benzenepropanoic Acid-d7 Sodium. Molecular formula: C15H[15N]O4D7.Na. Mole weight: 310.38. | |
| Esmolol-[d7] hydrochloride | Esmolol-[d7] hydrochloride is the labelled salt of Esmolol, which is a cardioselective beta1 adrenergic receptor blocker. Synonyms: Esmolol-d7 hydrochloride; 4-[2-Hydroxy-3-[(1-methylethyl-d7)amino]propoxy]benxzenepropanoic Acid Methyl Ester Hydrochloride; ASL-8052-d7; Brevibloc-d7. Grade: 98%. CAS No. 1346598-13-7. Molecular formula: C16H18D7NO4.HCl. Mole weight: 338.88. | |
| Esmolol HCl | Esmolol HCl is an impurity of Esmolol. Esmolol is a cardioselective β-blocker which has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. Uses: Adrenergic beta-antagonists. Synonyms: Esmolol hydrochloride; 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic acid methyl ester hydrochloride. Grade: >98%. CAS No. 81161-17-3. Molecular formula: C16H25NO4.HCl. Mole weight: 331.83. | |
| Esmolol hydrochloride | Esmolol hydrochloride is a beta adrenergic receptor blocker. Uses: Scientific research. Group: Signaling pathways. CAS No. 81161-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1392. | |
| Glibenclamide (5-Chloro-N- [4- (cyclohexyl ureidosulfonyl ) phene thyl ] -2-methoxybenzamide , Glyburide, N-p-[2- (5-Chloro-2-methoxybenzamido) ethyl]benzenesulfonyl-N?-cyclohexylurea) | Cell-permeable. An anti-diabetic agent. ATP-sensitive potassium channel (KATP) blocker. Inhibits KATP currents in the pancreatic beta cells causing an increase in intracellular Ca2+ and insulin secretion. Group: Biochemicals. Grades: Highly Purified. CAS No. 10238-21-8. Pack Sizes: 500mg, 1g. US Biological Life Sciences. | Worldwide |
| Gliclazide | Gliclazide is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Uses: Hypoglycemic agents. Synonyms: Gliclazide; Diamicron; Glimicron; Nordialex; Diaikron; S-1702; S-852; S1702; S852; S 1702; S 852. Grade: >98%. CAS No. 21187-98-4. Molecular formula: C15H21N3O3S. Mole weight: 323.41. | |
| Gliclazide | Gliclazide (S1702) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC 50 of 184 nM. Gliclazide is used as an antidiabetic [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S1702; SE1702. CAS No. 21187-98-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B0753. | |
| Gliclazide EP Impurity G | Gliclazide EP Impurity G is an impurity of Gliclazide. Gliclazide is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Synonyms: N-(p-Tolylsulfonyl)-4,4a,5,6,7,7a-hexahydrocyclopenta[d]pyridazine-3-carboxamide. Grade: > 95%. Molecular formula: C15H19N3O3S. Mole weight: 321.40. | |
| Hydroxy Timolol | A metabolite of Ticlopidine which is a non-cardioselective beta-blocker and it has no intrinsic sympathomimetic or membrane stabilizing effect. Synonyms: 2-[[(2S)-2-Hydroxy-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]propyl]amino]-2-methyl-1-propanol. Grade: > 95%. Molecular formula: C13H24N4O4S. Mole weight: 332.42. | |
| Hypaconitine | Hypaconitine, a neuromuscular blocker, is a diterpene alkaloid found in the root of Aconitum carmichaelii. It is the primary constituent responsible for the neuromuscular blocking action of aconite root. It could inhibit CaM expression and Cx43 (Ser368) phosphorylation. It has anti-inflammatory effect. Uses: A neuromuscular blocker could inhibit cam expression and cx43 (ser368) phosphorylation. it has anti-inflammatory effect. Synonyms: (1-alpha,6-alpha,14-alpha,15-alpha,16-beta)-acetatebenzoat; 15-tetraol,16,16-trimethoxy-4-(methoxymethyl)-20-methyl-18-aconitane-14; Aconitane-8,13,14,15-tetrol,1,6,16-trimethoxy-4-(methoxymethyl)-20-methyl-,8-acetate 14-benzoate, (1α,6α,14α,15α,16β)-; (1α,6α,14α,15α,16β)1,6,16-TriMethoxy-4-(MethoxyMethyl)-20-Methylaconitane-8,13,14,15-tetrol 8-Acetate 14-Benzoate; Japaconitine B1; Deoxymesaconitine. Grade: >98%. CAS No. 6900-87-4. Molecular formula: C33H45NO10. Mole weight: 615.3. | |
| Landiolol hydrochloride | Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta -blocker (β1/β2 selectivity?=?255:1, a half-life of 4?min), acts as an adrenoceptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ONO1101 hydrochloride. CAS No. 144481-98-1. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100607A. | |
| Levobetaxolol hydrochloride | Levobetaxolol hydrochloride is a beta-adrenergic receptor inhibitor (beta blocker) that can lower the pressure in the eye. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Betaxolol hydrochloride; AL-1577A. CAS No. 116209-55-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0381B. | |
| Nadolol-[d9] | Nadolol-[d9] is the deuterium labelled Nadolol, which is a non-selective beta blocker. Synonyms: 5-[3-[(1,1-Dimethylethyl-d9)amino]-2-hydroxypropoxy]-1,2,3,4-tetrahydro-2,3-naphthalenediol; Anabet-d9; Corgard-d9; SQ 11725-d9; Solgol-d9. Grade: >98%. CAS No. 94513-92-5. Molecular formula: C17H18D9NO4. Mole weight: 318.46. | |
| Nebivolol | Nebivolol (R 065824) is an orally active beta receptor blocker and has the high beta(1)-receptor affinity. Nebivolol has direct vasodilator properties and adrenergic blocking characteristics. Nebivolol can be used for the research of kinds of diseases such as hypertension, coronary artery disease, congestive heart failure and ischemic heart disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 065824. CAS No. 118457-14-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0203. | |
| Nebivolol hydrochloride | Nebivolol (R 065824) hydrochloride is an orally active beta receptor blocker and has the high beta(1)-receptor affinity.Nebivolol hydrochloride has direct vasodilator properties and adrenergic blocking characteristics. Nebivolol hydrochloride can be used for the research of kinds of diseases such as hypertension, coronary artery disease, congestive heart failure and ischemic heart disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 065824 hydrochloride. CAS No. 152520-56-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0203A. | |
| Nebivolol Hydrochloride (rel- (aR, aR, 2R, 2S)-a, a-[iminobis (methylene)]bis[6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-methanol] Hydrochloride, b1-Adrenoceptor Antagonist, Nebivolol Hydrochloride, Nebilet, R-65824, Narbivolol) | A competitive, highly selective beta-1-adrenoceptor antagonist (more than 40-fold selective for beta-1 than beta-2; Ki1 and beta-2, respectively). The most beta-1-selective chemical of the beta-blockers tested so far. Used for treatment of essential hypertension and highly cardioselective. Induces mild vasodialation via a nitric oxide- and cGMP-depedent pathways (EC50 = 11.36uM in renal arteries). Group: Biochemicals. Grades: Highly Purified. CAS No. 152520-56-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| p-Cresol | p-Cresol is used in the synthesis of Bupranolol (B689650), a non-selective beta blocker. Group: Biochemicals. Alternative Names: 4-Methylphenol; p-Cresol; 1-Hydroxy-4-methylbenzene; 1-Methyl-4-hydroxybenzene; 4-Cresol; 4-Hydroxytoluene; 4-Methylphenol; NSC 3696; p-Cresylic Acid; p-Hydroxytoluene; p-Methylhydroxybenzene; p-Methylphenol; p-Oxytoluene; p-Toluol; p-Tolyl Alcohol. Grades: Highly Purified. CAS No. 106-44-5. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| p-Cresol-[d8] | P-Cresol-[d8] is the labelled form of p-Cresol. p-Cresol is used in the synthesis of Bupranolol, a non-selective beta blocker. Synonyms: 4-Methylphenol-d8; 4-(Methyl-d3)phen-2,3,5,6-d4-ol-d. Grade: ≥98% by CP; ≥98% atom D. CAS No. 190780-66-6. Molecular formula: C7D8O. Mole weight: 116.19. | |
| p-Cresol-[methyl-13C] | P-Cresol-[methyl-13C] is the labelled form of p-Cresol. p-Cresol is used in the synthesis of Bupranolol, a non-selective beta blocker. Synonyms: 4-Methyl-13C-phenol; p-Cresol-α-13C; Phenol-4-(methyl-13C). Grade: 99% by CP; 99% atom 13C. CAS No. 121474-53-1. Molecular formula: C6[13C]H8O. Mole weight: 109.13. | |
| Pindolol | Pindolol (LB-46) is a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, also functions as a 5-HT1A receptor weak partial antagonist (Ki=33nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: LB-46. CAS No. 13523-86-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0982. | |
| Pindolol-[d7] | Pindolol-[d7] is the labelled analogue of Pindolol, which is a β-adrenergic blocker and could be used as an antihypertensive and antiglaucoma agent. Synonyms: Pindolol-d7; 1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol-d7; (+/-)-4-[2-Hydroxy-3-(isopropylamino)propoxy]indole-d7; Apo-pindol-d7; Betapindol-d7; Decreten-d7; Pectobloc-d7; Prinodolol-d7; (±)-Pindolol-d7(iso-propyl-d7). Grade: 95% by HPLC; 98% atom D. CAS No. 1185031-19-9. Molecular formula: C14H13D7N2O2. Mole weight: 255.37. | |
| Propafenone hydrochloride | Propafenone is a Class 1C antiarrhythmic as sodium channel blocker by slowing the influx of sodium ions into the cardiac muscle cells. Uses: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. it also has weak beta-blocking activity. Synonyms: 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone; 2-(2'-Hydroxy-3'-propylaminopropoxy)-omega-phenylpropiophenone. Grade: ≥98%. CAS No. 34183-22-7. Molecular formula: C21H27NO3·HCl. Mole weight: 377.91. | |
| Propranolol-[d7] hydrochloride | Propranolol-[d7] hydrochloride is a labelled salt of Propranolol. Propranolol is a beta blocker used for the treatment of high blood pressure, irregular heartbeats, shaking (tremors), etc. Synonyms: 1-Isopropylamino-D7-3-(naphthalen-1-yl-oxy)-propan-2-ol hydrochloride; 1-(Naphthalen-1-yloxy)-3-((propan-2-yl-d7)amino)propan-2-ol hydrochloride; (+/-)-Propranolol-(isopropyl-d7) hydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 1613439-56-7. Molecular formula: C16H15D7ClNO2. Mole weight: 302.85. | |
| (R)-3-Isopropylamino-1,2-propanediol | An impurity of Metoprolol. Metoprolol is a selective beta-1 receptor blocker used primarily to treat hypertension, angina pectoris, heart failure, and certain arrhythmias. Synonyms: (R)-1-Isopropylaminopropanediol; (R)-3-(Isopropylamino)propane-1,2-diol; (+)-3-Isopropylamino-1,2-propanediol; (2R)-3-[(1-Methylethyl)amino]-1,2-propanediol; (2R)-3-[(Propan-2-yl)amino]propane-1,2-diol; 1,2-Propanediol 3-[(1-methylethyl)amino]-, (2R)-. Grade: ≥95%. CAS No. 97988-45-9. Molecular formula: C6H15NO2. Mole weight: 133.19. | |
| (R)-O-Demethylmetoprolol | (R)-O-Demethylmetoprolol is an impurity of Betaxolol, which is a selective beta1 adrenergic receptor blocker for the treatment of hypertension and glaucoma. Synonyms: O-Demethylmetoprolol, (+)-; (R)-(+)-O-Demethylmetoprolol. CAS No. 131564-70-0. Molecular formula: C14H23NO3. Mole weight: 253.342. | |
| (R)-Propranolol glucuronide | (R)-Propranolol glucuronide, a beta-blocker metabolite used in the efficient treatment of high blood pressure, angina, and tremors, takes shape via a phase II metabolic reaction known as glucuronidation, as it travels through the liver. The compound's emergence enables the effortless removal of its parent compound, propranolol, from the body. The intricacies of the process involved in the development of (R)-Propranolol glucuronide, enable it to be a potential breakthrough substance, with the prospect of yielding unparalleled results in the treatment of the aforementioned conditions. Synonyms: (+)-Propranolol glucuronide; (1R)-1-[[(1-Methylethyl)amino]methyl]-2-(1-naphthalenyloxy)ethyl β-D-glucopyranosiduronic acid; β-D-Glucopyranosiduronic acid, 1-[[(1-methylethyl)amino]methyl]-2-(1-naphthalenyloxy)ethyl, (R)-. CAS No. 58657-79-7. Molecular formula: C22H29NO8. Mole weight: 435.47. | |
| (S)-3-Isopropylamino-1,2-propanediol | An impurity of Metoprolol. Metoprolol is a selective beta-1 receptor blocker used primarily to treat hypertension, angina pectoris, heart failure, and certain arrhythmias. Synonyms: (S)-1-Isopropylaminopropanediol; (S)-3-(Isopropylamino)propane-1,2-diol; (-)-3-Isopropylamino-1,2-propanediol; (2S)-3-[(1-Methylethyl)amino]-1,2-propanediol; (2S)-3-[(Propan-2-yl)amino]propane-1,2-diol; 1,2-Propanediol 3-[(1-methylethyl)amino]-, (2S)-. Grade: ≥95%. CAS No. 90742-94-2. Molecular formula: C6H15NO2. Mole weight: 133.19. | |
| (S)-Atenolol | (S)-Atenolol is a potent beta-adrenoreceptor blocker. (S)-Atenolol has the potential for the research of cardiovascular disorder [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 93379-54-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-17498A. | |
| (S)-Hydroxy Timolol | (S)-(-)-Hydroxy Timolol is a metabolite of the non-selective beta-adrenergic receptor blocker, Timolol (T443710). Group: Biochemicals. Alternative Names: 2-[[(2S)-2-Hydroxy-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]propyl]amino]-2-methyl-1-propanol. Grades: Highly Purified. CAS No. 1227468-61-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (S)-O-Demethylmetoprolol | (S)-O-Demethylmetoprolol is an impurity of Betaxolol, which is a selective beta1 adrenergic receptor blocker for the treatment of hypertension and glaucoma. Synonyms: O-Demethylmetoprolol, (-)-; (S)-(-)-O-Demethylmetoprolol. CAS No. 131564-69-7. Molecular formula: C14H23NO3. Mole weight: 253.342. | |
| (S)-Propranolol glucuronide | (S)-Propranolol glucuronide is the metabolite formed in vivo upon the administration of Propranololan efficacious beta-blocker that features in the treatment of hypertension, angina, and arrhythmias. This glucuronide is inactivated and subsequently renally cleared via the urinary tract. The relatively low molecular weight of (S)-Propranolol glucuronide, which permits facile urine excretion, belies its significance as a marker for assessing the pharmacokinetics of Propranolol. Synonyms: (S)-Propranolol-O-beta-D-glucuronide; (1S)-1-[[(1-Methylethyl)amino]methyl]-2-(1-naphthalenyloxy)ethyl β-D-glucopyranosiduronic acid; β-D-Glucopyranosiduronic acid, 1-[[(1-methylethyl)amino]methyl]-2-(1-naphthalenyloxy)ethyl, (S)-; (-)-Propranolol glucuronide. CAS No. 58657-78-6. Molecular formula: C22H29NO8. Mole weight: 435.47. | |
| Talatisamine | Talatisamine, a aconitum alkaloid, is specific K + channel blocker. Talatisamine attenuates beta-amyloid oligomers induced neurotoxicity in cultured cortical neurons [1]. Uses: Scientific research. Group: Natural products. CAS No. 20501-56-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0663. | |
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