Bradykinin Suppliers USA
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Product | Description | |
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Bradykinin-TR1 bradykinin-related peptide precursor Quick inquiry Where to buy Suppliers range | Bradykinin-TR1 bradykinin-related peptide precursor. Uses: Antimicrobial Peptides. Product ID: AF1080. | |
Bradykinin-TR1 bradykinin-related peptide precursor Quick inquiry Where to buy Suppliers range | Bradykinin-TR1 bradykinin-related peptide precursor is originally from Amolops granulosus. | |
Bradykinin Quick inquiry Where to buy Suppliers range | Bradykinin is an active peptide that is generated by the kallikrein-kinin system. It is a inflammatory mediator and also recognized as a neuromediator and regulator of several vascular and renal functions. Uses: Peptide Inhibitors. CAS No. 58-82-2. Product ID: R1245. | |
Bradykinin Quick inquiry Where to buy Suppliers range | Bradykinin is a nonapeptide messenger produced from kallidin in the blood. Bradykinin has the selectivity for B2 over B1 receptors. It exhibits hypotensive and anti-inflammatory properties. Uses: Hypotensive agent. Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; L-Bradykinin; Kallidin I; Callidin I; Kallidin 9. Grades: ≥95%. CAS No. 58-82-2. Molecular formula: C50H73N15O11. Mole weight: 1060.21. | |
Bradykinin 1-3 Quick inquiry Where to buy Suppliers range | Bradykinin 1-3, a 3-amino acid residue peptide fragment of Bradykinin, is an amino-truncated Bradykinin cleaved by Prolyl endopeptidase. Synonyms: Bradykinin (1-3); Arginyl-prolyl-proline; arginylprolylproline; L-Arginyl-L-prolyl-L-proline; H-RPP-OH. Grades: 95%. CAS No. 23815-91-0. Molecular formula: C16H28N6O4. Mole weight: 368.43. | |
Bradykinin 1-3 Quick inquiry Where to buy Suppliers range | Bradykinin (1-3) is a 3-amino acid residue peptide. Bradykinin (1-3) is an amino-truncated Bradykinin peptide, cleaved by Prolyl endopeptidase. Uses: Peptide Inhibitors. CAS No. 23815-91-0. Product ID: R1246. | |
Bradykinin 1-5 Quick inquiry Where to buy Suppliers range | Bradykinin (1-5) is a major stable metabolite of Bradykinin, formed by the proteolytic action of angiotensin-converting enzyme (ACE). Uses: Peptide Inhibitors. CAS No. 23815-89-6. Product ID: R1247. | |
Bradykinin 1-5 Quick inquiry Where to buy Suppliers range | Bradykinin 1-5 is the main stable metabolite of Bradykinin and is formed by proteolysis of angiotensin-converting enzyme (ACE). Synonyms: H-RPPGF-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanine; Bradykinin (1-5); Bradykinin Fragment 1-5; 1-5-Bradykinin (9Cl); N-[2-({[1-(Arginylprolyl)pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxyethylidene]phenylalanine. Grades: ≥95%. CAS No. 23815-89-6. Molecular formula: C27H40N8O6. Mole weight: 572.66. | |
Bradykinin 1-6 Quick inquiry Where to buy Suppliers range | Bradykinin 1-6, a stable metabolite of Bradykinin, is an amino-truncated Bradykinin peptide cleaved by carboxypeptidase Y (CPY). Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-serine; (S)-2-((S)-2-(2-((S)-1-((S)-1-((S)-2-amino-5-guanidinopentanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)acetamido)-3-phenylpropanamido)-3-hydroxypropanoic acid; Bradykinin (1-6). Grades: 95%. CAS No. 23815-88-5. Molecular formula: C30H45N9O8. Mole weight: 659.73. | |
Bradykinin 1-6 Quick inquiry Where to buy Suppliers range | Bradykinin (1-6) is an amino-truncated Bradykinin peptide. Bradykinin (1-6) is a stable metabolite of Bradykinin, cleaved by carboxypeptidase Y (CPY). Uses: Peptide Inhibitors. CAS No. 23815-88-5. Product ID: R1248. | |
Bradykinin:1-7 Quick inquiry Where to buy Suppliers range | Bradykinin (1-7) is an amino-truncated Bradykinin peptide. Bradykinin (1-7) is a metabolite of Bradykinin, cleaved by endopeptidase. Uses: API. CAS No. 23815-87-4. Product ID: 10-101-291. | |
Bradykinin 2-9 Quick inquiry Where to buy Suppliers range | Bradykinin 2-9, a metabolite of Bradykinin, is an amino-truncated Bradykinin peptide cleaved by Aminopeptidase P. Synonyms: Des-Arg1-bradykinin; H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; Bradykinin fragment 2-9; 2-9-Bradykinin. Grades: ≥95%. CAS No. 16875-11-9. Molecular formula: C44H61N11O10. Mole weight: 904.02. | |
Bradykinin 2-9 Quick inquiry Where to buy Suppliers range | Bradykinin (2-9) is an amino-truncated Bradykinin peptide. Bradykinin (2-9) is a metabolite of Bradykinin, cleaved by Aminopeptidase P. Uses: Peptide Inhibitors. CAS No. 16875-11-9. Product ID: R1250. | |
Bradykinin Acetate Quick inquiry Where to buy Suppliers range | Bradykinin is a physiologically and pharmacologically active peptide of the kinin group of proteins, consisting of nine amino acids. Uses: API. CAS No. 6846-3-3. Product ID: 10-101-72. | |
Bradykinin Acetate Quick inquiry Where to buy Suppliers range | Bradykinin Acetate. Uses: For analytical and research use. Group: Building Blocks; Chiral Molecules. Alternative Names: H 1970, (S)-2-((S)-2-((S)-1-((S)-2-((S)-2-(2-((S)-1-((S)-1-((S)-2-Amino-5-guanidinopentanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)acetamido)-3-phenylpropanamido)-3-hydroxypropanoyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-5-guanidinopentanoic Acid. CAS No. 6846-3-3. IUPAC Name: acetic acid;(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoic acid. Molecular formula: C50H73N15O11.C2H4O2. Mole weight: 1120.26. Catalog: APS6846033. SMILES: CC (=O)O. N[C@@H] (CCCNC (=N)N)C (=O)N1CCC[C@H]1C (=O)N2CCC[C@H]2C (=O)NCC (=O)N[C@@H] (Cc3ccccc3)C (=O)N[C@@H] (CO)C (=O)N4CCC[C@H]4C (=O)N[C@@H] (Cc5ccccc5)C (=O)N[C@@H] (CCCNC (=N)N)C (=O)O. Format: Neat. | |
Bradykinin Fragment 1-7 Quick inquiry Where to buy Suppliers range | Bradykinin Fragment 1-7 is a seven-membered oligopeptide. Synonyms: Arg-Pro-Pro-Gly-Phe-Ser-Pro; Des-8,9-BK. Grades: ≥97% by HPLC. CAS No. 23815-87-4. Mole weight: 756.85. | |
Bradykinin-GN_4 antimicrobial peptide precursor Quick inquiry Where to buy Suppliers range | Bradykinin-GN_4 antimicrobial peptide precursor. Uses: Antimicrobial Peptides. Product ID: AF890. | |
Bradykinin-GN_4 antimicrobial peptide precursor Quick inquiry Where to buy Suppliers range | Bradykinin-GN_4 antimicrobial peptide precursor is originally from Amolops granulosus. | |
Bradykinin, H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH (RPPGFSPFR) Quick inquiry Where to buy Suppliers range | Induces the release of nitric oxide. Other physiological functions include stimulation of pain receptors, inhibition of cAMP accumulation, and induction of smooth muscle contraction and vasodilation. Also involved in edema resulting from trauma or injury. Improves post-ischemic recovery of heart via a nitric oxide-dependent mechanism. Group: Biochemicals. Grades: Highly Purified. CAS No. 58-82-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??N??O??. US Biological Life Sciences. | Worldwide |
(D-Arg0,Hyp3,Igl5,D-Igl7,Oic8)-Bradykinin Quick inquiry Where to buy Suppliers range | (D-Arg0,Hyp3,Igl5,D-Igl7,Oic8)-Bradykinin, a bradykinin antagonist, shows high affinity for both BK receptors. Uses: Bradykinin receptor antagonists. Synonyms: B9430; H-D-Arg-Arg-Pro-Hyp-Gly-Gly(indan-2-yl)-Ser-D-Gly(indan-2-yl)-Oic-Arg-OH; (N-(D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolyl-glycyl-2-indan-2-yl-L-glycyl-L-seryl-2-indan-2-yl-D-glycyl)-(2S,3aS,7aS)-octahydroindole-2-carbonyl)-L-arginine; H-D-Arg-Arg-Pro-Hyp-Gly-Igl-Ser-D-Igl-Oic-Arg-OH; L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-(2S)-2-(2,3-dihydro-1H-inden-2-yl)glycyl-L-seryl-(2R)-2-(2,3-dihydro-1H-inden-2-yl)glycyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-. Grades: ≥95%. CAS No. 180981-09-3. Molecular formula: C64H95N19O13. Mole weight: 1338.56. | |
[Des-Arg9]-Bradykinin Quick inquiry Where to buy Suppliers range | [Des-Arg9]-Bradykinin is a selective Bradykinin(B1) receptor agonist and increases intracellular Ca2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice. Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanine; 9-De-arg-bradykinin; 9-Des-arg-BK; Des-arg(9)-bradykinin; 9-de-L-Argininebradykinin; 1-8-Bradykinin. Grades: ≥95%. CAS No. 15958-92-6. Molecular formula: C44H61N11O10. Mole weight: 904.02. | |
[Des-Arg9]-Bradykinin Quick inquiry Where to buy Suppliers range | [Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors. Uses: Peptide Inhibitors. CAS No. 15958-92-6. Product ID: R1119. | |
[Des-Arg9]-Bradykinin acetate Quick inquiry Where to buy Suppliers range | [Des-Arg9]-Bradykinin acetate is a Bradykinin B1 receptor agonist that displays selectivity for B1 over B2 receptors. Uses: Peptide Inhibitors. CAS No. 23827-91-0. Product ID: R1120. | |
[Des-Arg9]-Bradykinin TFA Quick inquiry Where to buy Suppliers range | [Des-Arg9]-Bradykinin TFA is a selective Bradykinin(B1) receptor agonist and increases intracellular Ca2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice. Synonyms: 1-8-Bradykinin, mono(trifluoroacetate) (salt); H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-OH.TFA; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanine trifluoroacetic acid. Grades: ≥95%. CAS No. 199433-70-0. Molecular formula: C44H61N11O10.C2HF3O2. Mole weight: 1018.05. | |
des-Arg9-[Leu8]-Bradykinin acetate salt Quick inquiry Where to buy Suppliers range | ≥97% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 115035-45-5. Pack Sizes: 25MG. Mole weight: 870.01. Catalog: AP115035455. Assay: ≥97% (HPLC). | |
Galanin (1-13)-Bradykinin (2-9) amide Quick inquiry Where to buy Suppliers range | Galanin (1-13)-Bradykinin (2-9) amide is a high affinity ligand and antagonist of galanin receptor. Synonyms: M35; Galanin Receptor Ligand M35; H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-NH2; glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparagyl-L-seryl-L-alanyl-glycyl-L-tyrosyl-L-leucyl-L-leucyl-glycyl-L-prolyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-argininamide; M35 Peptide. Grades: ≥95%. CAS No. 142846-71-7. Molecular formula: C107H153N27O26. Mole weight: 2233.52. | |
Lys-Bradykinin Quick inquiry Where to buy Suppliers range | Lys-Bradykinin is an endogenous bradykinin receptor agonist with selectivity for the B2 receptor (Ki = 2.54 and 0.63 nM at human B1 and B2 receptors, respectively). It is used as a hypotensive agent that reduces peripheral vascular resistance in vivo. Uses: Hypotensive agent. Synonyms: Kallidin. CAS No. 342-10-9. Molecular formula: C56H85N17O12. Mole weight: 1188.39. | |
Lys-Bradykinin acetate Quick inquiry Where to buy Suppliers range | Lys-Bradykinin acetate is an endogenous bradykinin receptor agonist with selectivity for the B2 receptor (Ki = 2.54 and 0.63 nM at human B1 and B2 receptors, respectively). It is used as a hypotensive agent that reduces peripheral vascular resistance in vivo. Synonyms: H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH.CH3CO2H; L-lysyl-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine acetic acid. Grades: ≥95%. Molecular formula: C58H89N17O14. Mole weight: 1248.43. | |
Lys-[Des-Arg9]Bradykinin Quick inquiry Where to buy Suppliers range | Lys-[Des-Arg9]Bradykinin is a potent and highly selective bradykinin B1 receptor agonist (Ki value 0.12 and > 30000 nM at human B1 and B2 receptors, respectively) with 16-fold potency against [Des-Arg9]-Bradykinin. It is used as a hypotensive agent and reduces peripheral vascular resistance in vivo. Uses: Hypotensive agent. Synonyms: des-Arg10-Kallidin; [Lys-des-Arg9]-Bradykinin. CAS No. 71800-36-7. Molecular formula: C50H73N13O11. Mole weight: 1032.21. | |
[Lys-des-Arg9]-Bradykinin Quick inquiry Where to buy Suppliers range | ≥95% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 71800-36-7. Pack Sizes: 1MG. Mole weight: 1032.20. Catalog: AP71800367. Assay: ≥95% (HPLC). | |
Lys-[Des-Arg9]Bradykinin acetate Quick inquiry Where to buy Suppliers range | Lys-[Des-Arg9]Bradykinin acetate is a potent and highly selective bradykinin B1 receptor agonist (Kis are 0.12 and >30000 nM at human B1 and B2 receptors, respectively) with 16-fold potency against [Des-Arg9]-Bradykinin. It is used as a hypotensive agent and reduces peripheral vascular resistance in vivo. Synonyms: H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-OH.CH3CO2H; L-lysyl-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanine acetic acid; 1-9-Kallidin acetate; N2-L-Lysyl-9-de-L-arginine-Bradykinin acetate. Grades: ≥95%. CAS No. 2760881-54-5. Molecular formula: C52H77N13O13. Mole weight: 1092.27. | |
[Phe8Y(CH-NH)Arg9]-Bradykinin Quick inquiry Where to buy Suppliers range | [Phe8Y(CH-NH)Arg9]-Bradykinin is a selective bradykinin B2 receptor agonist with 5-fold potency against bradykinin in vivo. It is resistant to carboxypeptidase cleavage. Uses: Hypotensive agent. Synonyms: Ppcna-BK; 8-Phe-9-psi-CH2NH-arg-bradykinin. CAS No. 118122-39-7. Molecular formula: C50H75N15O10. Mole weight: 1046.23. | |
Sar-[D-Phe8]-des-Arg9-Bradykinin Quick inquiry Where to buy Suppliers range | Sar-[D-Phe8]-des-Arg9-Bradykinin is a potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cleavage. It shows hypotensive and angiogenic activity in vivo. Uses: Hypotensive agent. Synonyms: Sar[DPhe8][des-Arg9]BK; [N-methylglycine,D-Phe8,des-Arg9]bradykinin. CAS No. 126959-88-4. Molecular formula: C47H66N12O11. Mole weight: 975.11. | |
1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid Ethyl Ester is a useful synthetic intermediate. It is used to prepare quinapril derivatives as bradykinin B2 receptor antagonists. It is also used to synthesize quinolizidinone carboxylic acid selective M1 allosteric modulators. Group: Biochemicals. Grades: Highly Purified. CAS No. 41234-43-9. Pack Sizes: 250mg, 2.5g. Molecular Formula: C12H15NO2, Molecular Weight: 205.25. US Biological Life Sciences. | Worldwide |
1,3-Dichloro-2-methyl-benzene Quick inquiry Where to buy Suppliers range | 1,3-Dichloro-2-methyl-benzene is a useful synthetic intermediate. It can be used to prepare aryloxymethyl-substituted dibenzo[b,f]azocines as potential protein kinase A inhibitors. It can also be used to prepare dimethylglycine sulfonamides as potential bradykinin hB2 receptor antagonists. Isoconazole Impurity 10. Group: Biochemicals. Grades: Highly Purified. CAS No. 118-69-4. Pack Sizes: 10g, 25g. Molecular Formula: C7H6Cl2, Molecular Weight: 161.03. US Biological Life Sciences. | Worldwide |
(1-6)-Icatibant Quick inquiry Where to buy Suppliers range | (1-6)-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: D-arginyl-L-arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanine; D-Arg-Arg-Pro-Hyp-Gly-Thi-OH. CAS No. 2698340-93-9. Molecular formula: C31H50N12O8S. Mole weight: 750.88. | |
17-ODYA Quick inquiry Where to buy Suppliers range | 17-Octadecynoic acid is a suicide inhibitor of LTB4 ω-oxidase. 17-ODYA can completely inhibit the bradykinin-dependent transport of sodium chloride in rat TALH cells at a concentration of 10 μM. Synonyms: Alkynyl Stearic Acid;17-Octadecynoic acid. Grades: ≥98% by HPLC. CAS No. 34450-18-5. Molecular formula: C18H32O2. Mole weight: 280.45. | |
3-[4-[ (Methylamino) carbonyl]phenyl]-2-propenoic Acid Quick inquiry Where to buy Suppliers range | 3-[4-[ (Methylamino) carbonyl]phenyl]-2-propenoic Acid can be used as reactant/reagent in preparation of benzimidazoles and analogs as bradykinin antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 160648-00-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C11H11NO3, Molecular Weight: 205.21. US Biological Life Sciences. | Worldwide |
4-Cyano-L-β-homophenylglycine Quick inquiry Where to buy Suppliers range | 4-Cyano-L-β-homophenylglycine is used as a reactant in the preparation of novel diaminochroman carboxamides as potent nonpeptide antagonists of bradykinin B1 receptor. Synonyms: H-Phg(4-CN)-(C#CH2)OH; H-β-Phe(4-CN)-OH; (R)-3-Amino-3-(4-cyanophenyl)propanoic acid. Grades: ≥ 95%. CAS No. 738606-24-1. Molecular formula: C10H10N2O2. Mole weight: 190.2. | |
(7-10)-Icatibant Quick inquiry Where to buy Suppliers range | (7-10)-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: L-seryl-D-1,2,3,4-tetrahydroisoquinolyl-3-Carbonyl-L-octahydroindole-2-carboxamido-L-arginine; H-Ser-D-Tic-Oic-Arg-OH; L-Arginine, L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3aβ,7aβ)-octahydro-1H-indole-2-carbonyl-; ((2S,3aS,7aS)-1-((R)-2-(L-seryl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)octahydro-1H-indole-2-carbonyl)-L-arginine. CAS No. 148416-85-7. Molecular formula: C28H41N7O6. Mole weight: 571.68. | |
Ac-Icatibant Quick inquiry Where to buy Suppliers range | Ac-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: Ac-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH; Acetyl-D-arginyl-L-arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanyl-L-seryl-D-1,2,3,4-tetrahydroisoquinolyl-L-octahydroindole-L-arginine; L-Arginine, N2-acetyl-D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-. CAS No. 193618-65-4. Molecular formula: C61H91N19O14S. Mole weight: 1346.58. | |
Antagonist G Quick inquiry Where to buy Suppliers range | Antagonist G is a substance P analog, which is a broad spectrum neuropeptide growth factor antagonist and antiproliferative agent. It was developed for the treatment of small cell lung cancer. It could inhibit neuropeptide-dependent and -independent proliferation of small cell lung cancer in vitro. It also inhibits growth of SCLC xenografts in mice in vivo. It blocks Swiss 3T3 cell growth induced by vasopressin, gastrin-releasing peptide and bradykinin. It activates JNK and stimulates apoptosis. It is an anticancer agent and is resistant to degradation by peptidases. Synonyms: [Arg6,D-Trp7,9,N-MePhe8]-Substance P(6-11). Grades: 98%. CAS No. 115150-59-9. Molecular formula: C49H66N12O6S. Mole weight: 951.20. | |
Antagonist G Quick inquiry Where to buy Suppliers range | Antagonist G is a potent vasopressin antagonist. Antagonist G is also a weak antagonist of GRP and Bradykinin. Antagonist G induces AP-1 transcription and sensitizes cells to chemotherapy. Uses: API. CAS No. 115150-59-9. Product ID: 10-101-206. | |
Avoralstat Quick inquiry Where to buy Suppliers range | Avoralstat, also known as BCX-4161, is an oral plasma kallikrein (PKK) inhibitor and Bradykinin inhibitor, used to treat hereditary angioedema. Synonyms: 3-[2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl]-6-(cyclopropylmethylcarbamoyl)pyridine-2-carboxylic acid; BCX-4161; BCX 4161; BCX4161; Avoralstat. CAS No. 918407-35-9. Molecular formula: C28H27N5O5. Mole weight: 513.54. | |
Bombinakinin-GAP Quick inquiry Where to buy Suppliers range | Bombinakinin-GAP is a bioactive bradykinin-related peptide that reduces 60% food intake following i.c.v. administration in rats. Synonyms: BOMBINAKININ-GAP; 573671-91-7; AKOS024457065; Bombinakinin M Gene Associated Peptide. CAS No. 573671-91-7. Molecular formula: C145H219N39O39S3. Mole weight: 3228.75. | |
Bombinakinin M Quick inquiry Where to buy Suppliers range | Bombinakinin M is a potent bradykinin receptor agonist with selectivity for mammalian arterial smooth muscle bradykinin receptors, displaying ~ 50-fold greater potency than bradykinin. Synonyms: Maximakinin. CAS No. 509151-65-9. Molecular formula: C100H159N31O24. Mole weight: 2179.55. | |
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P Quick inquiry Where to buy Suppliers range | [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P is a broad spectrum neuropeptide inverse agonist and antagonist. It acts as a full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM) and antagonist at tachykinin, bradykinin, CCK and bombesin receptors. It induces apoptosis and inhibits cancer cell growth in vitro. Synonyms: 1-Arg-5-Phe-7,9-Trp-11-Leu-substance P; D-Arg(10)-D-Phe(5)-D-Trp(7,9)-Leu(11)-SP; substance P, phenylalanyl(5)-tryptophyl(7,9)-leucine(11)-. CAS No. 96736-12-8. Molecular formula: C79H109N19O12. Mole weight: 1516.85. | |
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate Quick inquiry Where to buy Suppliers range | [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate is a broad-spectrum neuropeptide inverse agonist and antagonist. It acts as a full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM) and antagonist at tachykinin, bradykinin, CCK, and bombesin receptors. It induces apoptosis and inhibits cancer cell growth in vitro. Synonyms: H-D-Arg-Pro-Lys-Pro-D-Phe-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2.CH3CO2H; D-arginyl-L-prolyl-L-lysyl-L-prolyl-D-phenylalanyl-L-glutaminyl-D-tryptophyl-L-phenylalanyl-D-tryptophyl-L-leucyl-L-leucinamide acetic acid; [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P acetate. Grades: ≥95%. CAS No. 2918771-49-8. Molecular formula: C81H113N19O14. Mole weight: 1576.91. | |
Des-D-Arg(1)-Icatibant Quick inquiry Where to buy Suppliers range | Des-D-Arg(1)-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: L-Arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanyl-L-seryl-D-1,2,3,4-tetrahydroisoquinolyl-L-octahydroindole-L-arginine; Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH; Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH; L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-L-arginine; Bradykinin, 3-(trans-4-hydroxy-L-proline)-5-[3-(2-thienyl)-L-alanine]-7-(D-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid)-8-[(2α,3aβ,7aβ)-L-octahydro-1H-indole-2-carboxylic acid]-. CAS No. 130334-60-0. Molecular formula: C53H77N15O12S. Mole weight: 1148.35. | |
Des-L-Arg(2)-Icatibant Quick inquiry Where to buy Suppliers range | Des-L-Arg(2)-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: D-Arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanyl-L-seryl-D-1,2,3,4-tetrahydroisoquinolyl-L-octahydroindole-L-arginine; D-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH; L-Arginine, D-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-. CAS No. 193740-38-4. Molecular formula: C53H77N15O12S. Mole weight: 1148.35. | |
Ecallantide Quick inquiry Where to buy Suppliers range | HAE is caused by a mutation of the C1-inhibitor gene. Defective or missing C1-inhibitor permits activation of kallikrein, a protease that is responsible for liberating bradykinin from its precursor kininogen. An excess of bradykinin leads to fluid leakage from blood vessels, causing swelling of tissues typical of HAE.Ecallantide suppresses this pathogenetic mechanism by selectively and reversibly inhibiting the activity of plasma kallikrein. Uses: API. CAS No. 460738-38-9. Product ID: 10-101-160. | |
ELN 441958 Quick inquiry Where to buy Suppliers range | ELN441958 is a novel, potent and selective bradykinin B1 receptor antagonist with Ki value of 0.26 nM. It competitively inhibited the binding of the agonist [3H]DAKD to the human B1 receptor in IMR-90 lung fibroblast cell membranes. It is highly selective for B1 over B2 receptors and >500/ 2000-fold selective for the B1 over μ/δ-opioid receptor. It also inhibited human μ-, δ-, κ- opioid receptors and muscarinic M1 receptor with Ki values of 0.13, 0.69, 1.5 and 0.37 μM, respectively. It exhibited good permeability and metabolic stability in vitro. It exhibited high oral bioavailability and moderate plasma half-lives in rats and rhesus monkeys. It does not inhibit the activation of the human bradykinin B2 receptor at concentrations up to 10 μM. It has a moderate clearance and volume of distribution in both species following i.v. administration, consistent with the high metabolic stability in rat, rhesus, and human microsomes. Uses: Eln441958 exhibited high oral bioavailability and moderate plasma half-lives. Synonyms: ELN441958; ELN 441958; ELN-441958;7-Chloro-2-[3-[[9-(pyridin-4-yl)-3,9-diazaspiro[5.5]undecan-3-yl]carbonyl]phenyl]-2,3-dihydroisoindol-1-one. Grades: >98%. CAS No. 913064-47-8. Molecular formula: C29H29ClN4O2. Mole weight: 501.02. | |
H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH·AcOH Quick inquiry Where to buy Suppliers range | H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH·AcOH. Group: Biochemicals. Alternative Names: Bradykinin. Grades: Highly Purified. CAS No. 6846-3-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
Icatibant Quick inquiry Where to buy Suppliers range | Icatibant (Firazyr) is a synthetic peptidomimetic drug consisting of ten amino acids, and acts as an effective and specific antagonist of bradykinin B2 receptors. It has been approved in the EU for use in hereditary angioedema, and is under investigation for a number of other conditions in which bradykinin is thought to play a significant role. Uses: API. CAS No. 130308-48-4. Product ID: 10-101-163. | |
Icatibant Quick inquiry Where to buy Suppliers range | Icatibant(HOE-140) is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-; H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH; D-Arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-L-arginine; HOE140; HOE 140; HOE-140. Grades: >98%. CAS No. 130308-48-4. Molecular formula: C59H89N19O13S. Mole weight: 1304.52. | |
Icatibant Acetate Quick inquiry Where to buy Suppliers range | Icatibant acetate is a selective antagonist of bradykinin B2 receptors. Icatibant is a medication approved for the treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: HOE 140 Acetate; HOE140 Acetate; HOE-140 Acetate; L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (1:x); H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH.CH3CO2H; L-Arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3aβ,7aβ)-octahydro-1H-indole-2-carbonyl-, acetate (salt); Firazyr. Grades: ≥95%. CAS No. 138614-30-9. Molecular formula: C59H89N19O13S.xC2H4O2. Mole weight: 1304.52 (free base). | |
L-Arg(1)-Icatibant Quick inquiry Where to buy Suppliers range | L-Arg(1)-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: L-arginyl-L-arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanyl-L-seryl-D-1,2,3,4-tetrahydroisoquinolyl-L-octahydroindole-L-arginine; Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH; L-Arginine, L-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-. CAS No. 193618-59-6. Molecular formula: C59H89N19O13S. Mole weight: 1304.54. | |
M617 Quick inquiry Where to buy Suppliers range | M617 is a chimeric peptide that acts as a selective galanin GAL1 receptor agonist with Ki values of 0.23 and 5.71 nM for GAL1 and GAL2 receptors respectively. It enhances food consumption in rats following i.c.v. administration and reduces CAP-induced inflammatory pain. Synonyms: M617; M 617; M-617; Galanin(1-13)-Gln14-bradykinin(2-9)amide. CAS No. 860790-38-1. Molecular formula: C112H161N29O28. Mole weight: 2361.68. | |
MEN 11270 Quick inquiry Where to buy Suppliers range | MEN 11270 is a B2 bradykinin receptor antagonist. It can block hypotension and bronchoconstriction in vivo. Uses: Bradykinin receptor antagonists. Synonyms: MEN 11270; MEN11270; MEN-11270. Grades: ≥95% by HPLC. CAS No. 235082-52-7. Molecular formula: C60H90N20O11S. Mole weight: 1299.56. | |
MEN 11270 Quick inquiry Where to buy Suppliers range | MEN 11270 is a peptide antagonist of the B2 bradykinin receptor (pKi = 10.3) and conformationally constrained cyclized analog of HOE 140 (Cat. No. 3014). It can blocks hypotension and bronchoconstriction in vivo. Uses: Peptide Inhibitors. CAS No. 235082-52-7. Product ID: R0807. | |
MK0686 Quick inquiry Where to buy Suppliers range | MK0686 is a bradykinin B1 receptor antagonist. It exhibits suitable pharmacokinetic properties and efficient ex vivo receptor occupancy for further development as a novel approach for the treatment of pain and inflammation. It had been in phase II clinical trials by Merck Sharp & Dohme for the treatment of postherpetic neuralgia, postoperative pain and osteoarthritis. But it is discontinued now. Uses: Mk0686 is used for the treatment of postherpetic neuralgia, postoperative pain and osteoarthritis. Synonyms: MK0686; MK 0686; MK-0686;Methyl 2-chloro-6- [3-fluoro-4- [ (1R) -1- [ [1- [ (2, 2, 2-trifluoroacetyl) amino] cyclopropanecarbonyl] amino] ethyl] phenyl] benzoate; Methyl (R)-3-chloro-3'-fluoro-4'-(1-(1-(2,2,2-trifluoroacetamido)cyclopropane-1-carboxamido)ethyl)-[1,1'-biphenyl]-2-carboxyla. Grades: 98%. CAS No. 578727-68-1. Molecular formula: C22H19ClF4N2O4. Mole weight: 486.85. | |
Perindopril Erbumine Quick inquiry Where to buy Suppliers range | Perindopril Erbumine displays a higher binding affinity for the bradykinin binding sites than the angiotensin I binding sites of the angiotensin-converting enzyme (ACE) with bradykinin/angiotensin I selectivity ratio of 1.44. Uses: Angiotensin-converting enzyme inhibitors. Synonyms: S9490-3. Grades: >98%. CAS No. 107133-36-8. Molecular formula: C19H32N2O5.C4H11N. Mole weight: 441.6. | |
Phosphoramidon Quick inquiry Where to buy Suppliers range | Phosphoramidon is a neutral endopeptidase 24.11 (NEP, neprilysin; EC 3.4.24.11) (Ki=2nM) inhibitor, which cleaves bioactive peptides such as bradykinin, neurotensin, and enkephalin. It also inhibits neprilysin 2 (Ki~2nM) and endothelin-converting enzyme (ECE) (IC50=0.68 μM). Uses: Peptide Inhibitors. CAS No. 119942-99-3. Product ID: R0805. | |
R 715 Quick inquiry Where to buy Suppliers range | R 715 is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49),without activity on B2 receptors. Uses: Bradykinin receptor antagonists. Synonyms: R 715; R715; R-715. Grades: >98%. CAS No. 185052-09-9. Molecular formula: C57H81N13O12. Mole weight: 1140.35. | |
R 715 Quick inquiry Where to buy Suppliers range | Potent and selective antagonist of bradykinin b1 receptor (pa2 = 8.49), which displays no activity at b2 receptors, and reduces mechanical hypernociception in a mouse model of neuropathic pain. Uses: Peptide Inhibitors. CAS No. 185052-09-9. Product ID: R1087. | |
R 892 Quick inquiry Where to buy Suppliers range | R 892 is a selective, highly potent, and metabolically stable bradykinin B1 receptor antagonist (ID50= 2.8 and > 600 nM at B1 and B2 receptors respectively). It may be useful for the assessment of the physiological and pathological roles of kinin B1 receptors. R 892 exhibits no intrinsic agonist activity and is resistant to aminopeptidase and kininase II (ACE) cleavage. Synonyms: R 892; R892; R-892; (1Z, 4Z, 6S, 7Z, 9S, 10Z, 12R, 13Z, 15S) -1- ( (S) -1- ( (S) -1- ( (S) -2- ( (Z) - ( (S) -6-amino-1-hydroxy-2- ( (Z) - (1-hydroxyethylidene) amino) hexylidene) amino) -5-guanidinopentanoyl) pyrrolidine-2-carbonyl) pyrrolidin-2-yl) -6-benzyl-15- ( (S) -sec-butyl) -1, 4, 7, 10, 13-pentahydroxy-9- (hy. Grades: >98%. CAS No. 229030-05-1. Molecular formula: C58H83N13O12. Mole weight: 1154.37. | |
R 892 Quick inquiry Where to buy Suppliers range | Potent and selective bradykinin B1 receptor antagonist (ID50 values are 2.8 and > 600 nM at B1 and B2 receptors respectively), which shows no intrinsic agonist activity and is resistant to aminopeptidase and kininase II (ACE) cleavage. Displays hypertensive activity in vivo. Uses: Peptide Inhibitors. CAS No. 229030-05-1. Product ID: R1002. | |
Retrobradykinin Quick inquiry Where to buy Suppliers range | Retrobradykinin, a bradykinin analog nonapeptide, shows no significant kinin activity. Synonyms: RFPSFGPPR. CAS No. 5991-13-9. Molecular formula: C50H73N15O11. Mole weight: 1060.22. | |
Safotibant Quick inquiry Where to buy Suppliers range | Safotibant is a non-peptide bradykinin B1 receptor antagonis. It is used for the topical treatment of diabetic macular oedema. It displayed binding Ki values of 0.35 and 6.5 nM at cloned human and mouse B1 receptors respectively. It also reversed acute inflammatory pain induced by carrageenan, and persistent inflammatory pain induced by CFA. It was developed by Sanofi and was in clinic phase 2 trials, but now it is terminated. Uses: Safotibant is used for the topical treatment of diabetic macular oedema. Synonyms: N-[[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]methyl]-2-[2-[(4-methoxy-2,6-dimethylphenyl)sulfonyl-methylamino]ethoxy]-N-methylacetamide;LF-22-0542; LF22-0542; LF 22-0542; LF-220542; LF220542; LF 220542; Safotibant. Grades: 98%. CAS No. 633698-99-4. Molecular formula: C25H34N4O5S. Mole weight: 502.63. | |
SSR 240612 hydrochloride Quick inquiry Where to buy Suppliers range | SSR 240612 is a bradykinin B1 receptor inhibitor, displaying selectivity for B1 receptor over B2 receptor with Ki values of 0.48-0.73 and 358-481 nM, respectively. Synonyms: SSR 240612; SSR-240612; SSR240612; SSR 240612 HCl. Grades: ≥95%. CAS No. 464930-42-5. Molecular formula: C42H52N4O7S·HCl. Mole weight: 793.41. |