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C75 is a novel, potent synthetic inhibitor of fatty acid synthase (FAS), which is used as a tool for studying fatty acid synthesis in metabolic disorders and cancer. Synonyms: C 75 trC-75 trans-racemic; trans-C75; C 75; C75; C-75. Grades: >98%. CAS No. 218137-86-1. Molecular formula: C14H22O4. Mole weight: 254.32.
C75
C75 is a synthetic fatty-acid synthase ( FASN ) inhibitor; inhibits prostate cancer cells PC3 with an IC 50 of 35 μM [1] [2] [3]. C75 is a potent CPT1A activator [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 218137-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12364.
C75 trans
trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a well-known fatty acid synthase (FAS) inhibitor. Studies show that trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a cell cycle arrest inducer in hepatocellular carcinoma (HCC) cell lines. It has also been shown to blocks resistin-induced increases in lipid accumulation by human macrophages. Synonyms: C 75 trC-75 trans-racemic; trans-C75. Grades: >98%. CAS No. 191282-48-1. Molecular formula: C14H22O4. Mole weight: 254.32.
Inhibitor of fatty acid synthase (FAS) reducing food intake and body weight in mice. Exhibits irreversible slow-binding biphasic inactivation of FAS. Down regulates neuropeptide Y and Agouti-related protein expression. Has been proposed to activiate CPT-1 activity in liver and adipose tissue, leading to increased fatty acid oxidation and energy production. Shows significant in vivo antitumor activity in human breast cancer cells.Suppresses DNA replication and induces apoptosis. FAS inhibition by C75 leads to dramatic accumulation of the CDK inhibitor p27KIP1 from cytosol to cell nuclei. Group: Biochemicals. Alternative Names: [Trans-4-carboxy-5-octyl-3-methylene-butyrolactone]. Grades: Highly Purified. CAS No. 191282-48-1. Pack Sizes: 1mg. US Biological Life Sciences.
2,4,6-Tri(9H-carbazol-9-yl)-1,3,5-triazine (purified by sublimation)
2,4,6-Tri(9H-carbazol-9-yl)-1,3,5-triazine (purified by sublimation). Group: other material building blocksorganic light-emitting diode (oled) materials. CAS No. 134984-37-5. Product ID: 9-[4,6-di(carbazol-9-yl)-1,3,5-triazin-2-yl]carbazole. Molecular formula: 576.66. Mole weight: C39H24N6. C1=CC=C2C (=C1) C3=CC=CC=C3N2C4=NC (=NC (=N4) N5C6=CC=CC=C6C7=CC=CC=C75) N8C9=CC=CC=C9C1=CC=CC=C18. InChI=1S/C39H24N6/c1-7-19-31-25 (13-1)26-14-2-8-20-32 (26)43 (31)37-40-38 (44-33-21-9-3-15-27 (33)28-16-4-10-22-34 (28)44)42-39 (41-37)45-35-23-11-5-17-29 (35)30-18-6-12-24-36 (30)45/h1-24H. NPLMKKHOVKWGEO-UHFFFAOYSA-N. >98.0%(HPLC)(N).
2,6-Bis(9H-carbazol-9-yl)pyridine
2,6-Bis(9H-carbazol-9-yl)pyridine. Uses: A highly efficient host material for blue phosphorescent oleds. Group: Electronic materials organic light-emitting diode (oled) materials. Alternative Names: PYD-2Cz. CAS No. 168127-49-9. Pack Sizes: 500 mg in glass bottle. Product ID: 9-(6-carbazol-9-ylpyridin-2-yl)carbazole. Molecular formula: 409.49. Mole weight: C29H19N3. C1=CC=C2C (=C1)C3=CC=CC=C3N2C4=NC (=CC=C4)N5C6=CC=CC=C6C7=CC=CC=C75. InChI=1S/C29H19N3/c1-5-14-24-20 (10-1)21-11-2-6-15-25 (21)31 (24)28-18-9-19-29 (30-28)32-26-16-7-3-12-22 (26)23-13-4-8-17-27 (23)32/h1-19H. CUQGKGMUSQKHFO-UHFFFAOYSA-N. >98.0%(HPLC)(N).
2-Oxocyclohexane propanoic Acid Ethyl Ester
2-Oxocyclohexane propanoic Acid Ethyl Ester is an intermediate in the synthesis of Hexahydrocoumarin (H293905), a derivative of Coumarin (C755380) that is used as a fragrance ingredient. Group: Biochemicals. Grades: Highly Purified. CAS No. 4095-2-7. Pack Sizes: 500mg, 1g. Molecular Formula: C11H18O3. US Biological Life Sciences.
Worldwide
3-(2-Oxo-cyclohexyl)-propionic Acid
3-(2-Oxo-cyclohexyl)-propionic Acid is an intermediate in the synthesis of Hexahydrocoumarin (H293905), a derivative of Coumarin (C755380) that is used as a fragrance ingredient. Group: Biochemicals. Grades: Highly Purified. CAS No. 2275-26-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H14O3. US Biological Life Sciences.
4-Chloro-3-(3-isopropyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)aniline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ZERENEX E/5111057;4-CHLORO-3-(3-ISOPROPYL[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZOL-6-YL)ANILINE;AKOS BB-7847;ASISCHEM C75323. Product Category: Heterocyclic Organic Compound. CAS No. 889945-20-4. Molecular formula: C12H12ClN5S. Mole weight: 293.78. Product ID: ACM889945204. Alfa Chemistry ISO 9001:2015 Certified.
(6,6)-Phenyl-c61butyric acid butyl ester
(6,6)-Phenyl-c61butyric acid butyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (6,6)-PHENYL-C61BUTYRIC ACID BUTYL ESTER;1-(3-Butoxycarbonylpropyl)-1-phenyl-[6.6]C61,[60]PCB-C4,PCBB;1-(3-Butoxycarbonylpropyl)-1-phenyl-[6.6]C61;[6,6]-Phenyl-C61 butyric acid butyl ester,1-(3-Butoxycarbonylpropyl)-1-phenyl-[6.6]C61, PCBB, [60]PCB-C4;[60. Product Category: Organic & Printed Electronics. CAS No. 571177-66-7. Molecular formula: C75H20O2. Mole weight: 952.981. Product ID: ACM571177667. Alfa Chemistry ISO 9001:2015 Certified.
7-Hydroxy-4- (trifluoromethyl) coumarin
7-Hydroxy-4- (trifluoromethyl) coumarin is an halogenated metabolite of Coumarin (C755380), an naturally occurring organic compound that exists in many plants. Coumarin is the precursor molecule in the synthesis of various synthetic anti-coagulant such as warfarin (W498500). Group: Biochemicals. Alternative Names: 4-(Trifluoromethyl)-7-hydroxycoumarin; 4- (Trifluoromethyl) umbelliferone; 7-Hydroxy-4-(trifluoromethyl)-2H-chromen-2-one; 7-Hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one; NSC 138174. Grades: Highly Purified. CAS No. 575-03-1. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
9,9'-(5-Bromo-1,3-phenylene)bis(9H-carbazole)
9,9'-(5-Bromo-1,3-phenylene)bis(9H-carbazole). Group: Small molecule semiconductor building blockssemiconductor blocks. Alternative Names: 1-Bromo-3,5-bis(carbazol-9-yl)benzene. CAS No. 750573-24-1. Product ID: 9-(3-bromo-5-carbazol-9-ylphenyl)carbazole. Molecular formula: 487.39. Mole weight: C30H19BrN2. C1=CC=C2C (=C1)C3=CC=CC=C3N2C4=CC (=CC (=C4)Br)N5C6=CC=CC=C6C7=CC=CC=C75. SJOKONNBSXFPSN-UHFFFAOYSA-N. InChI=1S/C30H19BrN2/c31-20-17-21 (32-27-13-5-1-9-23 (27)24-10-2-6-14-28 (24)32)19-22 (18-20)33-29-15-7-3-11-25 (29)26-12-4-8-16-30 (26)33/h1-19H. 98%.
ACTH (1-13) is a 13-aa peptide with cytoprotective effects in the model of ethanol induced gastric lesions in rats. Uses: Hormones. Synonyms: Adrenocorticotropic Hormone (1-13); H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-OH; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valine; Tridecactide; Des-acetyl MSH; DE-alpha-Msh; (Des-acetyl)-alpha-MSH; alpha 1-13-Corticotropin, human; Desacetyl alpha-melanocyte-stimulating hormone; a1-13-Corticotropin. Grades: ≥95%. CAS No. 22006-64-0. Molecular formula: C75H106N20O19S. Mole weight: 1623.83.
ACTH (1-13) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt
ACTH (1-13) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: SYSMEHFRWGKPV-OH. Grades: ≥98%. Molecular formula: C75H106N20O19S·xCF3COOH. Mole weight: 1623.83.
Agelaia-mastoparan
Agelaia-mastoparan is an antimicrobial peptide produced by Agelaia pallipes (Neotropical social wasp). It has antibacterial activity against Gram-positive and Gram-negative bacteria. Synonyms: Agelaia-MP; H-Ile-Asn-Trp-Leu-Lys-Leu-Gly-Lys-Ala-Ile-Ile-Asp-Ala-Leu-NH2; L-isoleucyl-L-asparagyl-L-tryptophyl-L-leucyl-L-lysyl-L-leucyl-glycyl-L-lysyl-L-alanyl-L-isoleucyl-L-isoleucyl-L-alpha-aspartyl-L-alanyl-L-leucinamide. Grades: ≥96%. Molecular formula: C75H127N19O17. Mole weight: 1566.96.
Amphipathic peptide CT1
Amphipathic peptide CT1 is an antimicrobial peptide produced by venom, Scorpiops tibetanus (Scorpion). It has antibacterial activity. Synonyms: StCT1; Non-disulfide-bridged peptide 5; NDBP-5; Gly-Phe-Trp-Gly-Ser-Leu-Trp-Glu-Gly-Val-Lys-Ser-Val-Val-NH2. Grades: ≥95%. Molecular formula: C75H108N18O18. Mole weight: 1549.80.
Apelin-13 trifluoroacetate salt
Apelin-13 trifluoroacetate salt is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM. Synonyms: Apelin-13 triTFA. Molecular formula: C75H114F9N23O22S. Mole weight: 1892.89.
(Arg)9, FAM-labeled
It is a fluorescent (FAM)-labeled cell permeable peptide, Abs/Em=494/521 nm. Synonyms: FAM-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH. Grades: ≥95%. Molecular formula: C75H120N36O16. Mole weight: 1781.99.
CREBtide acetate
CREBtide acetate, a synthetic substrate for PKA (Km = 3.9 μM), is a synthetic peptide consisting of 13 amino acids that is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein). Synonyms: H-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser-Tyr-Arg-OH.CH3CO2H; L-lysyl-L-arginyl-L-arginyl-L-alpha-glutamyl-L-isoleucyl-L-leucyl-L-seryl-L-arginyl-L-arginyl-L-prolyl-L-seryl-L-tyrosyl-L-arginine acetic acid. Grades: ≥95%. Molecular formula: C75H133N29O21. Mole weight: 1777.07.
Cyanine5.5 NHS ester
Cyanine5.5 NHS ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1H-Benz[e]indolium,2-[5-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)-1,3-pentadien-1-yl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl-,chloride(1:1). Product Category: Cyanine Fluorophores. Appearance: Deep blue powder. CAS No. 1469277-96-0. Molecular formula: C44H46ClN3O4. Mole weight: 716.31. Purity: 95%+. IUPACName: (2,5-dioxopyrrolidin-1-yl)6-[1,1-dimethyl-2-[5-(1,1,3-trimethylbenzo[e]indol-3-ium-2-yl)penta-2,4-dienylidene]benzo[e]indol-3-yl]hexanoate;chloride. Canonical SMILES: CC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)C)C=CC=CC=C4C(C5=C(N4CCCCCC(=O)ON6C(=O)CCC6=O)C=CC7=CC=CC=C75)(C)C)C.[Cl-]. Product ID: ACM1469277960-1. Alfa Chemistry ISO 9001:2015 Certified.
(D-ARG1,D-PRO2,D-TRP7,9,LEU11)-SUBSTANCE P
It is a potent antagonist for substance P and bombesin. Synonyms: Substance P, arg(1)-pro(2)-trp(7),(9)-leunh(2)(11)-; Argininyl(1)-prolyl(2)-tryptophyl-7,9-leucinamide(11)-substance P. CAS No. 84676-91-5. Molecular formula: C75H108N20O13. Mole weight: 1497.79.
(Des-acetyl)-alpha-MSH is an antimicrobial peptide produced by Homo sapiens. It has antibacterial and antifungal activity. Synonyms: Alpha-MSH; Sequence 3 from Patent US 7244710; H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2. Grades: 96%. Molecular formula: C75H107N21O18S. Mole weight: 1622.87.
[D-Phe12,Leu14]-Bombesin
[D-Phe12,Leu14]-Bombesin is a bombesin receptor antagonist. It inhibits bombesin binding to rat brain (IC50 = 2 μM), inhibits amylase release in vitro (IC50 = 4 μM), and attenuates bombesin-mediated suppression of food intake in vivo. Synonyms: [D-Phe12,Leu14]-Bombesin; 108437-88-3; PYR-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-D-PHE-LEU-LEU-NH2; (D-Phe12,Leu14)-Bombesin; AKOS024457621; PD079499; HY-103287; CS-0027153. CAS No. 108437-88-3. Molecular formula: C75H114N22O18. Mole weight: 1610.9.
Dynorphin A (1-13)
Dynorphin A is an endogenous opioid peptide that preferentially activates κ opioid receptors. Synonyms: Dynorphin A Porcine Fragment 1-13; Porcine dynorphin A(1-13); H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysine; 1-13-Dynorphin A (swine). Grades: 98%. CAS No. 72957-38-1. Molecular formula: C75H126N24O15. Mole weight: 1603.95.
Dynorphin A (1-13) amide
Dynorphin A (1-13) amide is an antagonist of human MC1, MC3 and MC4 receptors. Synonyms: Dynorphin A (1-13), amide, porcine; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-NH2; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamide; Linear Dyn A-(1-13)NH2; L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N5-(diaminomethylene)-L-ornithyl-N5-(diaminomethylene)-L-ornithyl-L-isoleucyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamide. Grades: ≥95%. CAS No. 79515-34-7. Molecular formula: C75H127N25O14. Mole weight: 1602.97.
ELA-14 (human)
ELA-14 (human) is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: Elabela (19-32). CAS No. 1886973-05-2. Molecular formula: C75H119N25O17S2. Mole weight: 1707.03.
Elisidepsin
Elisidepsin is a marine-derived, synthetic cyclic depsipeptide with potential antineoplastic activity. Elisidepsin is a derivative of a natural marine compound that belongs to a family of dehydro aminobutyric acid-containing peptides (kahalalides) isolated from the herbivorous marine mollusk Elysia rufescens. Although the primary mechanism of action has yet to be elucidated, this agent exhibits anti-proliferative activity in a wide variety of cancer cell types, including breast, colon, pancreas, lung, and prostate; it appears to induce oncolytic rather than apoptotic cell death. Synonyms: PM-02734; N-[(4S)-4-methylhexanoyl]-D-valyl-L-threonyl-L-valyl-D-valyl-D-prolyl-L-ornithyl-N-{(3S,6Z,9S,12R,15R,18R,19R)-9-benzyl-15-[(2S)-butan-2-yl]-6-ethylidene-3,12-diisopropyl-19-methyl-2,5,8,11,14,17-hexaoxo-1-oxa-4,7,10,13,16-pentaazacyclononadecan-18-yl}-D-alloisoleucinamide. CAS No. 681272-30-0. Molecular formula: C75H124N14O16. Mole weight: 1477.90.
Fluciclatide F-18
Fluciclatide-F18 is a radiopharmaceutical compound of a small synthetic cyclic peptide containing an RGD-sequence (Arg-Gly-Asp) labeled with the positron-emitting isotope fluorine F 18 that may be used to selectively image tumor cells and tumor vasculature by PET imaging. The RGD motif of fluciclatide F 18 selectively binds to the alphaVbeta3 integrin receptor, commonly upregulated on the surfaces of tumor cells and endothelial cells of tumor vasculature. This agent may be of use in visualizing and quantifying the development of tumor vascularity in response to antiangiogenic agents. Synonyms: [18F]AH111585; 18F-Fluciclatide; Fluciclatide (f-18). CAS No. 879894-01-6. Molecular formula: C75H115FN18O27S3. Mole weight: 1815.02.
Hibarimicin H
Hibarimicin H is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. Molecular formula: C75H98O33. Mole weight: 1527.56.
H-Ser-tyr-ser-met-glu-his-phe-arg-trp-gly-lys-pro-val-nh2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: des-Ac-|A-Melanocyte Stimulating Hormone; SYSMEHFRWGKPV-NH2. Product Category: Heterocyclic Organic Compound. CAS No. 53697-27-1. Molecular formula: C75H107N21O18S. Mole weight: 1622.85. Purity: 0.96. IUPACName: SYSMEHFRWGKPV amide. Canonical SMILES: CC(C)C(C(=O)N)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CNC=N5)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CO)N. Product ID: ACM53697271. Alfa Chemistry ISO 9001:2015 Certified.
H-Tyr-gly-gly-phe-leu-D-arg-arg-ile-arg-pro-lys-leu-lys-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TYR-GLY-GLY-PHE-LEU-D-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS;YGGFLD-RRIRPKLK;(D-ARG6)-DYNORPHIN A (1-13);[D-ARG6]-DYNORPHIN A (1-13), PORCINE;DYNORPHIN A PORCINE [D-ARG6]-FRAGMENT 1-13;H-TYR-GLY-GLY-PHE-LEU-D-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-OH;dynorphin A D-arg. Product Category: Heterocyclic Organic Compound. CAS No. 75921-87-8. Molecular formula: C75H126N24O15. Mole weight: 1603.95. Purity: 0.96. IUPACName: 6-amino-2-[[2-[[6-amino-2-[[1-[2-[[2-[[2-[[2-[[2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)p. Product ID: ACM75921878. Alfa Chemistry ISO 9001:2015 Certified.
Iα52 acetate
Iα52 acetate is a naturally processed peptide containing 52-68 residues of the mouse I-Eα chain that may contribute to the selection of immature T cells. Synonyms: Ala-Ser-Phe-Glu-Ala-Gln-Gly-Ala-Leu-Ala-Asn-Ile-Ala-Val-Asp-Lys-Ala-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C75H122N20O27. Mole weight: 1735.89.
Kahalalide F
Kahalalide F is one of a family of novel peptides isolated from the Hawaiian mollusk, Elysia rufescens. It is currently in Phase II trials for hepatocarcinoma. Kahalalide F (KF) is a novel antitumor drug of marine origin under clinical investigation. KF showed a potent cytotoxic activity against a panel of human prostate and breast cancer cell lines, with IC50 ranging from 0.07 μm (PC3) to 0.28 μm (DU145, LNCaP, SKBR-3, BT474, MCF7). Importantly, nontumor human cells (MCF10A, HUVEC, HMEC-1, IMR90) were 5-40 times less sensitive to the drug (IC50 = 1.6-3.1 μm). Synonyms: Kahalalide F; PM-92102; PM 92102; PM92102. CAS No. 149204-42-2. Molecular formula: C75H124N14O16. Mole weight: 1477.90.
KDAMP
HGAPDH is a cationic peptide isolated from Homo sapiens. It has activity against gram-negative bacteria. Synonyms: KDAMP 19-mer; H-Arg-Ala-Ile-Gly-Gly-Gly-Leu-Ser-Ser-Val-Gly-Gly-Gly-Ser-Ser-Thr-Ile-Lys-Tyr-al. Grades: 95.4%. Molecular formula: C75H127N23O25. Mole weight: 1751.0.
MASTP_PROSY Mastoparan
MASTP_PROSY Mastoparan has antibacterial activity. MASTP_PROSY Mastoparan was found in Protonectarina sylveirae [Brazilian wasp]. Grades: >96% by HPLC. Molecular formula: C75H128N20O17. Mole weight: 1581.94.
MCP
MCP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3-Bis(carbazol-9-yl)benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 550378-78-4. Molecular formula: C30H20N2. Mole weight: 408.49 g/mol. Purity: 95%+. IUPACName: 9-(3-carbazol-9-ylphenyl)carbazole. Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3N2C4=CC(=CC=C4)N5C6=CC=CC=C6C7=CC=CC=C75. Density: 1.21 g/ml. Product ID: ACM550378784. Alfa Chemistry ISO 9001:2015 Certified.
Membrane-Permeable Sequence, MPS
It corresponds to the membrane-permeable sequence designed from the carboxyl terminus of Gα subunits targeting G protein subunits. It is a membrane-translocating hydrophobic sequence specifically derived from the h-region of K-FGF (Kaposi fibroblast growth factor) signal peptide sequence. Synonyms: H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Lys-OH. Grades: >98%. Molecular formula: C75H135N17O17. Mole weight: 1547.01.
MMK 1
MMK 1 is a potent and selective human formyl peptide receptor FPR2 agonist (EC50 = 1, 2 and > 10 000 nM at mFRP2, hFPR2 and hFPR1 respectively). Some findings showed that the transient rise in intracellular free calcium induced by MMK-1 involves both a release of calcium from intracellular stores and an opening of channels in the plasma membrane. Synonyms: MMK 1; MMK1; MMK-1; (4S)-4-[[(2S)-2-amino-4-methylpentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-3-methylsulfanylpropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid. CAS No. 271246-66-3. Molecular formula: C75H123N19O18S. Mole weight: 1610.97.
N-(7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran-6-yl)hexadecanamide Sodium Salt
N-(7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran-6-yl)hexadecanamide is an derivative of Coumarin (C755380), an naturally occurring organic compound that exists in many plants. Coumarin is the precursor molecule in the synthesis of various synthetic anti-coagulant such as warfarin (W498500). Group: Biochemicals. Alternative Names: N-(7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran-6-yl)hexadecanamide Monosodium Salt. Grades: Highly Purified. CAS No. 113808-19-8. Pack Sizes: 2.5mg. US Biological Life Sciences.
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NFAT Inhibitor
A selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Synonyms: H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-OH; L-methionyl-L-alanyl-glycyl-L-prolyl-L-histidyl-L-prolyl-L-valyl-L-isoleucyl-L-valyl-L-isoleucyl-L-threonyl-glycyl-L-prolyl-L-histidyl-L-alpha-glutamyl-L-glutamic acid. Grades: >98%. CAS No. 249537-73-3. Molecular formula: C75H118N20O22S. Mole weight: 1683.93.
NFAT Inhibitor
Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells. Group: Biochemicals. Grades: Purified. CAS No. 249537-73-3. Pack Sizes: 1mg. Molecular Formula: C75H118N20O22S, Sequence: MAGPHPVIVITGPHEE. US Biological Life Sciences.
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N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5
N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5. Uses: Designed for use in research and industrial production. Product Category: Cyanine Fluorophores. CAS No. 2107273-76-5. Molecular formula: C63H79ClN4O10. Mole weight: 1087.8. Purity: 95%+. IUPACName: N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-[2-[2-[2-[2-[(2E)-2-[(2E,4E)-5-[1-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl]-3,3-dimethylindol-1-ium-2-yl]penta-2,4-dienylidene]-3,3-dimethylindol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]propanamide;chloride. Canonical SMILES: CC1(C2=CC=CC=C2[N+](=C1/C=C/C=C/C=C/3\C(C4=CC=CC=C4N3CCOCCOCCOCCOCCC(=O)NCCC(=O)N5CC6=CC=CC=C6C#CC7=CC=CC=C75)(C)C)CCOCCOCCOCCOC)C.[Cl-]. Product ID: ACM2107273765-1. Alfa Chemistry ISO 9001:2015 Certified.
o-Coumaric Acid 4-O- β-D-Glucuronide is a metabolite of either Coumarin (C755380) or o-Hydroxy-cinnamic Acid (614-60-8). Group: Biochemicals. Grades: Highly Purified. CAS No. 108884-00-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C15H16O9, Molecular Weight: 340.28. US Biological Life Sciences.
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o-Coumaric Acid 4-O- β-D-glucuronide-d4
o-Coumaric Acid 4-O- β-D-glucuronide-d4 is an isotopic analog of o-Coumaric Acid 4-O- β-D-Glucuronide (C755405), which is a metabolite of either Coumarin (C755380) or o-Hydroxy-cinnamic Acid (614-60-8). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H12D4O9, Molecular Weight: 344.31. US Biological Life Sciences.
Worldwide
Onjisaponin B
Onjisaponin B is extracted from the roots of Polygala tenuifolia. It was able to induce autophagy and accelerate both the removal of mutant huntingtin and A53T α-synuclein, which are highly associated with Huntington disease and Parkinson disease, respectively. It induces autophagy via the AMPK-mTOR signaling pathway. It increased the NGF level and may have potential therapeutic effects for the treatment of Alzheimer disease patients. Synonyms: Senegin III; Sinegin 3. Grades: >98%. CAS No. 35906-36-6. Molecular formula: C75H112O35. Mole weight: 1573.7.
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