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| Product | Description | |
|---|---|---|
| Calcium Acetate | Calcium Acetate. Grade: ACS. CAS: 62-54-4. Packing: Fiber Drums. |  New Jersey NJ |
| Calcium Acetate | CALCIUM ACETATE, HYDRATE, Reagent, powder, Formula: Ca(OOCCH3)2.xH2O. CAS No. 114460-21-8. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today! |  Texas TX |
| Calcium Acetate | White crystalline solid. Uses: food additive, deicer, preservative. Group: organic salt. CAS No. 62-54-4. |  |
| Calcium Acetate 62-54-4 | Calcium Acetate. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Calcium Acetate (Anhydrous) | Calcium Acetate (Anhydrous). Group: Polymerschemical resins. |  |
| Calcium Acetate BP/USP | Calcium Acetate BP/USP. CAS No. 62-54-4. Molecular formula: C4H6CaO4. |  |
| Calcium acetate hydrate | 100g Pack Size. Group: Buffers, Research Organics & Inorganics. Formula: C4H6CaO4 ·xH2O. CAS No. 62-54-4. Prepack ID 21537694-100g. Molecular Weight 158.17. See USA prepack pricing. |  |
| Calcium acetate hydrate | Calcium acetate hydrate. Group: Solution deposition precursors. Alternative Names: CALCIUM ACETATE H2O; CALCIUM ACETATE, HEMIHYDRATE; CALCIUM ACETATE HYDRATE; CALCIUM ACETATE, HYDRATED; CALCIUM ACETATE N-HYDRATE; ACETIC ACID, CALCIUM SALT HYDRATE; Calcium acetate hydrate, extra pure, 99%; Calcium acetate hydrate, Puratronic(R), 99.9965% (metal. CAS No. 114460-21-8. Molecular formula: 176.18. Mole weight: C4H8CaO5. 99%. | |
| Calcium acetate hydrate | Micro/NanoElectronics. Alternative Names: CALCIUM ACETATE H2O;CALCIUM ACETATE, HEMIHYDRATE;CALCIUM ACETATE HYDRATE;CALCIUM ACETATE, HYDRATED;CALCIUM ACETATE N-HYDRATE;ACETIC ACID, CALCIUM SALT HYDRATE;Calcium acetate hydrate, extra pure, 99%;Calcium acetate hydrate, Puratronic(R), 99.9965% (metal. CAS No. 114460-21-8. Molecular formula: C4H8CaO5. Mole weight: 176.18. Appearance: Powder. Purity: 0.99. Catalog: ACM114460218-1. |  |
| Calcium Acetate, Laboratory Grade, 500 g | Formula: Ca(CH3CO2)2 H2O. F. W: 176. 18. Storage Code: Green; general chemical storage. Alternative Names: Lime acetate, calcium diacetate. Grades: chem-grade laboratory. CAS No. 5743-26-0. Product ID: 851660. -- SOLD FOR EDUCATIONAL USE ONLY -- |  |
| Calcium acetate monohydrate | Calcium acetate monohydrate. Group: Biochemicals. Alternative Names: Acetic acid calcium salt hydrate. Grades: Highly Purified. CAS No. 5743-26-0. Pack Sizes: 2kg, 5kg. US Biological Life Sciences. |  Worldwide |
| Calcium Acetate Monohydrate | Calcium Acetate Monohydrate. CAS No. 5743-26-0. Molecular Formula Ca(CH3COO)2 * H2O. Chemical Reagents |  Cater Chemicals Corp. Illinois IL |
| Calcium acetate monohydrate 99+% ACS | Calcium acetate monohydrate 99+% ACS. Group: Biochemicals. Grades: ACS Grade. CAS No. 5743-26-0. Pack Sizes: 1Kg, 2.5Kg, 10Kg. US Biological Life Sciences. | Worldwide |
| Calcium Acetate Monohydrate, ACS | Calcium Acetate Monohydrate, ACS. Group: Biochemicals. Grades: ACS Grade. CAS No. 5743-26-0. Pack Sizes: 500g, 1Kg, 2.5Kg, 5Kg, 10Kg. US Biological Life Sciences. | Worldwide |
| Calcium2- [carboxymethyl- [2- [carboxymethyl- (2-oxido-2-oxoethyl) amino]ethyl]amino]acetate | Heterocyclic Organic Compound. CAS No. 12247-12-0. Molecular formula: C10H14CaN2O8. Mole weight: 330.305 g/mol. Catalog: ACM12247120. | |
| 2-[(3-Nitrophenyl)methylene]-3-oxo-butanoic Acid Propyl Ester | 2-[(3-Nitrophenyl)methylene]-3-oxo-butanoic Acid Propyl Ester is an intermediate in the synthesis of Lercanidipine, which is a dihydropyridine calcium channel blocker. Synonyms: Propyl (3-Nitrobenzylidene)acetoacetate; Propyl 2-(3-Nitrobenzylidene)-3-oxobutanoate; Butanoic Acid, 2-[(3-Nitrophenyl)Methylene]-3-Oxo-, Propyl Ester. CAS No. 77888-04-1. Molecular formula: C14H15NO5. Mole weight: 277.27. |  |
| 2-Cyanoethyl Acetoacetate | 2-Cyanoethyl Acetoacetate is an intermediate in the synthesis of Felodipine-d3 (F232377), a labelled dihydropyridine calcium channel blocker. Group: Biochemicals. Grades: Highly Purified. CAS No. 65193-87-5. Pack Sizes: 100mg, 1g. Molecular Formula: C7H9NO3, Molecular Weight: 155.15. US Biological Life Sciences. | Worldwide |
| 3-Oxo-butanoic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Ester | 3-Oxo-butanoic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Ester is an intermediate in the synthesis of Lercanidipine, which is a dihydropyridine calcium channel blocker. Synonyms: Butanoic acid, 3-oxo-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl ester; 1,1,N-trimethyl-N-(3,3-diphenylpropyl)-2-aminoethyl acetoacetate; 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanyl 3-oxobutanoate. Grades: ≥95%. CAS No. 100427-51-8. Molecular formula: C24H31NO3. Mole weight: 381.51. | |
| 4-(2-Phthalimidoethoxy)acetoacetic Acid Ethyl Ester | 4-(2-Phthalimidoethoxy)acetoacetic Acid Ethyl Ester is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: Ethyl 4-(2-Phthalimidoethoxy)acetoacetate; 4-[2-(1,3-Dioxo-1,3-dihydroisoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester; 4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester. Grades: >95%. CAS No. 88150-75-8. Molecular formula: C16H17NO6. Mole weight: 319.31. | |
| Acetic acid calcium salt | Acetic acid calcium salt is used as a preservative in oral and topical preparations. Oral calcium acetate is used as a complexing agent for hyperphosphatemia in dialysis patients. It is also used as a stabilizer, buffer and sequestrant in the food industry. Synonyms: Calcium Acetate; Brown Acetate; Calcium Diacetate; E 263; Gray Acetate; Lime Acetate; Lime Pyrolignite; PhosLo; Royen; Sanopan; Sorbo-Calcion; Teltozan. Grades: 98%. CAS No. 62-54-4. Molecular formula: C4H6CaO4. Mole weight: 158.17. | |
| Amlodipine Mannitol Adduct Acetate Salt | Amlodipine Mannitol Adduct Acetate Salt is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Grades: >95%. Molecular formula: C26H37ClN2O10.C2H4O2. Mole weight: 633.08. | |
| Apelin-12 acetate | Apelin-12 induces calcium mobilization in APJ-Gαq16 cells expressing human APJ and inhibits HIV-1 and HIV-2 infection in NP-2/CD4/APJ cells. Apelin-12 inhibits the JNK and p38 MAPK signaling pathway of the apoptosis-related MAPKs family, thus offering protection to neurons. Synonyms: Preproapelin (66-77) (human, bovine, mouse, rat) acetate; (Des-Gln1)-Apelin-13 (human, bovine, mouse, rat) acetate; Apelin Precursor (66-77) (human, bovine, mouse, rat) acetate. Molecular formula: C66H107N21O16S. Mole weight: 1482.77. | |
| ATI-2341 acetate | ATI-2341 acetate is a potent and functionally selective CXCR4 allosteric agonist that activates Gα1 rather than Gα13. ATI-2341 acetate activates the inhibitory heterotrimer G protein (GI) to promote the inhibition of cAMP production and induce calcium mobilization. Synonyms: palmitoyl-Met-Gly-Tyr-Gln-Lys-Lys-Leu-Arg-Ser-Met-Thr-Asp-Lys-Tyr-Arg-Leu-OH.CH3CO2H; N-palmitoyl-L-methionyl-glycyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-lysyl-L-leucyl-L-arginyl-L-seryl-L-methionyl-L-threonyl-L-alpha-aspartyl-L-lysyl-L-tyrosyl-L-arginyl-L-leucine acetic acid; N-(1-Oxohexadecyl)-L-methionylglycyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-lysyl-L-leucyl-L-arginyl-L-seryl-L-methionyl-L-threonyl-L-α-aspartyl-L-lysyl-L-tyrosyl-L-arginyl-L-leucine acetate; ATI 2341 acetate; ATI2341 acetate. Grades: ≥95%. Molecular formula: C106H182N26O27S2. Mole weight: 2316.87. | |
| CALP1 trifluoroacetate salt | CALP1 is an 8-residue calcium-like peptide that interacts with an EF hand motif based on the troponin C superfamily calcium binding site. CALP1 is also a cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site. CALP1 inhibits Ca2+-mediated cytotoxicity and apoptosis with IC50 of 52 μM and activates phosphodiesterase in the presence of calmodulin and absence of calcium. It also decreases radical production induced by phorbol 12-myristate 13-acetate in broncho-alveolar lavage cells. Synonyms: Calcium-like peptide 1. Grades: ≥95%. Molecular formula: C40H75N9O10·xCF3COOH. Mole weight: 842.08. | |
| CALP3 acetate | CALP3 acetate is a potent Ca2+ channel blocker that mimics [Ca2+]i increase by regulating the activity of calmodulin (CaM), Ca2+ channels, and pumps. CALP3 is a cell-permeable calmodulin (CaM) agonist binding to the EF-hand/Ca2+-binding site. Synonyms: H-Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-OH.CH3CO2H; L-valyl-L-lysyl-L-phenylalanyl-glycyl-L-valyl-glycyl-L-phenylalanyl-L-lysine acetic acid; CALP 3 acetate; CALP-3 acetate; Calcium-like peptide 3 acetate. Grades: ≥95%. Molecular formula: C46H72N10O11. Mole weight: 941.12. | |
| [D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt | DAMGO is an analog of μ-Receptor-specific enkephalin. It stimulates calcium-activated adenylyl cyclases related cAMP production. Synonyms: DAMGO acetate; DAGO acetate; Tyr-D-Ala-Gly-N-Methyl-Phe-Gly-ol; L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-L-phenylalaninamide monoacetate (salt); L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-N-alpha-methyl-L-phenylalaninamide monoacetate (salt). Grades: 95%. CAS No. 100929-53-1. Molecular formula: C28H39N5O8. Mole weight: 573.64. | |
| Diltiazem | Diltiazem is a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia as a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Uses: A nondihydropyridines (non-dhp) calcium channel blocker. Synonyms: Cardizem; D-cis-Diltiazem; [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate. Grades: ≥95%. CAS No. 42399-41-7. Molecular formula: C22H26N2O4S. Mole weight: 414.52. | |
| Diltiazem Malate | Diltiazem is a calcium channel antagonist. It can relax the smooth muscles in the walls of arteries, allow blood to flow more easily, and lower blood pressure. Meanwhile, it can lower blood pressure through acting on the heart itself to reduce the rate, strength, and conduction speed of each beat. Diltiazem can be used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. Uses: Hypertension, angina pectoris, and some types of arrhythmia. Synonyms: MK-793; MK 793; MK793; Tiamate; UNII-14Y6444DRP.;(+)-(2S,3S)-5-(2-(Dimethylamino)ethyl)-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester),(S)-malate (1:1);1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(di-methylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-(2S-cis)-, (S)-hydoxybutanedioate (1:1). Grades: 98%. CAS No. 144604-00-2. Molecular formula: C26H32N2O9S. Mole weight: 548.61. | |
| DP-b 99 | DP-b 99 is a zinc and calcium ions chelating agent potentially for the treatment of acute pancreatitis. DP-b99 is a newly developed lipophilic, cell-permeable derivative of BAPTA (1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid), that is under development as a neuroprotectant for the potential treatment of stroke, head trauma and neurological damage associated with coronary artery bypass graft. Synonyms: Glycine, N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-, 1,1'-bis[2-(octyloxy)ethyl] ester; DP-b99; DP-b-99; 2,2'-(((Ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis((2-(2-(octyloxy)ethoxy)-2-oxoethyl)azanediyl))diacetic acid; 1,2-Bis(2-aminophenoxy)ethane-N,N-di(2-octyloxyethyl acetate)-N,N-diacetic acid; N,N'-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)glycine 1,1'-bis[2-(octyloxy)ethyl] ester; DP-BAPTA-99. Grades: ≥95%. CAS No. 222315-88-0. Molecular formula: C42H64N2O12. Mole weight: 788.96. | |
| EDTA AM | EDTA AM is a cell-permeant calcium indicator. EDTA AM is loaded into live cells by incubation, and cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand. It has been used for investigations of the role of cytosolic Ca2+. Synonyms: EDTA tetra(acetoxymethyl ester); acetyloxymethyl 2-[[2-(acetyloxymethoxy)-2-oxoethyl]-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]ethyl]amino]acetate. CAS No. 162303-59-5. Molecular formula: C22H32N2O16. Mole weight: 580.49. | |
| Ethylenediaminetetraacetic acid dicalcium salt | Heterocyclic Organic Compound. Alternative Names: Antallin, Chelaton, Edetamin, Sormetal, Tetazine, Antalin, Edtacal, Mosatil, Tetacin, Versene, Edetate calcium, Tetacin-calcium, Rikelate calcium, Calcium EDTA, Calcium EDTA complex, Sodium calcium edetate, Calcium disodium EDTA, Calcium disodium edetate, Edetate calcium disodium, Calcitetracemate disodium. CAS No. 12264-18-5. Molecular formula: C10H14CaN2O8. Mole weight: 330.304760 [g/mol]. Purity: 0.96. IUPACName: calcium 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)amino]ethyl]amino]acetate. Canonical SMILES: C (CN (CC (=O)O)CC (=O)[O-])N (CC (=O)O)CC (=O)[O-]. [Ca+2]. ECNumber: 235-534-5. Catalog: ACM12264185. | |
| Gastrin I (human) acetate | Gastrin I (human) acetate, an endogenous peptide produced by the stomach, is a selective CCK2 receptor agonist that stimulates gastric acid secretion in vivo and increases cytoplasmic calcium levels in isolated rabbit gastric parietal cells (EC50 = 11 nM). Synonyms: Little gastrin I acetate; Gastrin-17 acetate; H-Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2.CH3CO2H; Gastrin-17 I (human) acetate; 5-Oxo-L-prolylglycyl-L-prolyl-L-tryptophyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-tyrosylglycyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide acetate; Human gastrin heptadecapeptide I acetate; Human gastrin I (1-17) acetate. Grades: ≥95%. Molecular formula: C99H128N20O33S. Mole weight: 2158.25. | |
| Heptaminol hydrochloride | Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP-2831 hydrochloride. CAS No. 543-15-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1231. |  |
| Native Bacillus polymyxa Dispase II | Dispase II is a neutral protease that hydrolyzes the N-terminal peptide bonds of non-polar amino acid residues. It may be used for separating many tissues and cells grown in vitro. The enzyme is very gentle and does not damage cell membranes. It can also be used to prevent clumping in suspension cultures. This protease cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin. Dispase II is specific for the cleavage of Leucine-Phenylalanine bonds. Ca2+, Mg2+, Mn2+, Fe2+, Fe3+ and Al3+ activate the enzyme. EDTA, EGTA, Hg2+ and other heavy metals inhibit the enzyme activity. The enzyme contains 1g-atom of zinc per g-mol of purif... it has been used in the treatment of rat heart pieces during the isolation of mitochondria from rat heart. it has also been used for the isolation of dental pulp stem cells (dpscs) by enzymatic hydrolysis. these cells have been compared with dpscs isolated by explant method to analyse their stem cell and differentiation properties. Group: Enzymes. Synonyms: Dispase II; Dispase; 42613-33-2; Protease from Bacillus polymyxa. CAS No. 42613-33-2. Dispase. Activity: > 0.5 units/mg solid. Storage: 2-8°C. Form: lyophilized powder containing calcium acetate and milk sugar. Source: Bacillus polymyxa. Dispase II; Dispase; 42613-33-2; Protease from Bacillus polymyxa. Cat No: NATE-0192. |  |
| Native Geobacillus stearothermophilus Thermolysin | Thermolysin is a thermostable neutral metalloproteinase enzyme produced by the Gram-positive bacteria Bacillus thermoproteolyticus. It requires one zinc ion for enzyme activity and four calcium ions for structural stability. Thermolysin specifically catalyzes the hydrolysis of peptide bonds containing hydrophobic amino acids. However thermolysin is also widely used for peptide bond formation through the reverse reaction of hydrolysis. Thermolysin is the most stable member of a family of metalloproteinases produced by various Bacillus species. These enzymes are also termed 'neutral' proteinases or thermolysin-like proteinases (TLPs). Suitable for cell culture. Applica... of n-terminal to phe which is preferred over the others. often used to do limited proteolysis for peptide mapping and studies of protein structure and conformational changes. Group: Enzymes. Synonyms: thermolysin; Bacillus thermoproteolyticus neutral proteinase; thermoase; thermoase Y10; TLN; EC 3.4.24.27. Enzyme Commission Number: EC 3.4.24.27. CAS No. 9073-78-3. TLN. Activity: 30-175 units/mg protein (E1%/280). Storage: -20°C. Form: lyophilized powder containing calcium and sodium acetate buffer salts. Source: Geobacillus stearothermophilus. thermolysin; Bacillus thermoproteolyticus neutral proteinase; thermoase; thermoase Y10; TLN; EC 3.4.24.27. Cat No: NATE-0704. | |
| Native Streptomyces griseus Aminopeptidase I | Aminopeptidase I from S. griseus has a fairly broad specificity, being able to remove the N-terminal residue of most proteins, except where the penultimate residue is an imino acid. It contains two Zn2+ binding sites. Aminopeptidase I from S. griseus is inhibited by 1,10-phenanthroline and is activated six-fold by Ca2+, which also stabilizes it against heat inactivation. This monomeric zinc metalloprotein has an isoelectric point (pI) of 5.4. Applications: Aminopeptidase i from streptomyces griseus may be used as a reagent for the analysis of protein structure and as a model for studies of proteolytic enzyme activation by calcium ions. it may be used as a reagent in the assay of endoprotease activities with a synthetic substrate in a two-stage assay. the lyophilized powder also contains calcium acetate. Group: Enzymes. Synonyms: aminopeptidase III; aminopeptidase yscI; leucine aminopeptidase IV; yeast aminopeptidase I; EC 3.4.11.22; 9031-94-1; Aminopeptidase I. Enzyme Commission Number: EC 3.4.11.22. CAS No. 9031-94-1. Aminopeptidase I. Activity: > 200 units/mg protein. Storage: -20°C. Form: lyophilized powder. Contains calcium acetate. Source: Streptomyces griseus. aminopeptidase III; aminopeptidase yscI; leucine aminopeptidase IV; yeast aminopeptidase I; EC 3.4.11.22; 9031-94-1; Aminopeptidase I. Cat No: NATE-0070. | |
| Native Tritirachium album limber Proteinase K | Proteinase K (PROK) is a serine protease with broad specificity towards aliphatic, aromatic and other hydrophobic amino acids. PROK has a molecular weight of 27,000 daltons and is Ca2+ dependent. It is not inactivated by metal ion chelating agents such as EDTA, sulfhydryl reagents, PCMB, TLCK, or TPCK. It also retains activity in 0.5% SDS. It can be inhibited by PMSF or DFP. Applications: Useful for the proteolytic inactivation of nucleases during the isolation of dna and rna. removes endotoxins that bind to cationic proteins such as lysozyme and ribonuclease a. reported useful for the isolation of hepatic, yeast, and mung bean mit ochondria determination of enzyme l o...oteinase; Tritirachium album proteinase K; endopeptidase K; 39450-01-6; protease K. Enzyme Commission Number: EC 3.4.21.64. CAS No. 39450-01-6. Purity: Purified to remove DNase and RNase. Proteinase K. Mole weight: 27 kDa. Activity: Type I, > 20 units per mg dry weight; Type II, > 400 u/ml. Storage: Powder: 2-8°C; Liquid: -20°C. Form: Type I, powder; Type II, Liquid in 20mg/ml in 10mM Tris-HCl, 1mM calcium acetate, pH 7.5 containing 50% glycerol. Source: Tritirachium album limber. Proteinase K; EC 3.4.21.64; Tritirachium alkaline proteinase; Tritirachium album serine proteinase; Tritirachium album proteinase K; endopeptidase K; 39450-01-6; protease K. Cat No: NATE-0637. | |
| Native Vibrio cholerae Neuraminidase | Neuraminidase enzymes are glycoside hydrolase enzymes (EC 3.2.1.18) that cleave the glycosidic linkages of neuraminic acids. Neuraminidase enzymes are a large family, found in a range of organisms. The best-known neuraminidase is the viral neuraminidase, a drug target for the prevention of the spread of influenza infection. The viral neuraminidases are frequently used as antigenic determinants found on the surface of the Influenza virus. Some variants of the influenza neuraminidase confer more virulence to the virus than others. Other homologs are found in mammalian cells, which have a range of functions. At least four mammalian sialidase homologs have been described in the...say of neuraminidase. Group: Enzymes. Synonyms: neuraminidase; sialidase; α-neuraminidase; acetylneuraminidase; exo-α-sialidase; EC 3.2.1.18; 9001-67-6. Enzyme Commission Number: EC 3.2.1.18. CAS No. 9001-67-6. Neuraminidase. Activity: Type I, 1-5 units/mg protein (Lowry, using NAN-lactose); Type II, 8-24 units/mg protein (Lowry, using NAN-lactose); Type III, > 1.5 units/mg protein. Storage: 2-8°C. Form: Type I, buffered aqueous solution; Aqueous solution, pH 5.5, containing 0.15 M NaCl and 4 mM CaCl2; Type II, buffered aqueous solution, Solution in 50 mM sodium acetate, pH 5.5, containing 0.15 M sodium chloride and 4 mM calcium chloride; Type III, sterile filte | |
| Propiverine Hydroxy Impurity | An impurity of Propiverine Propiverine. Propiverine is a muscarinic antagonist. It is an anticholinergic drug used for the treatment of urinary urgency, frequency and urge incontinence. Uses: Calcium channel blockers. Synonyms: Enpiperate; 3608-67-1; 1-methylpiperidin-4-yl 2-hydroxy-2,2-diphenylacetate; 1-Methyl-4-piperidyl diphenylglycolate; 4-NMPB; [3H]4NMPB; N-Methyl-4-piperidyl benzilate; 1-Methyl-4-piperidyl benzilate; NSC 172167; CHEMBL143228; QWK86805EB; N-methyl-4-piperidinyl benzilate; NSC-172167; Benzeneacetic acid. alpha.-hydroxy-.alpha.-phenyl-, 1-methyl-4-piperidinyl ester; Hydroxy-diphenyl-acetic acid 1-methyl-piperidin-4-yl ester; [3H]enpiperate. Grades: > 95%. CAS No. 3608-67-1. Molecular formula: C20H23NO3. Mole weight: 325.41. | |
| Sperabillin A | It is produced by the strain of Pseudomonas fluorescens YK-437. In vitro it has the effect of anti-pyomonas aeruginosa, alkali-producing faecal bacteria, acinetobacter calcium acetate and staphylococcus aureus. It also has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa resistant to methicillin, streptomycin, kanamycin, gentamicin, erythromycin, lincomycin, etc. It is used in mice infected with Staphylococcus aureus, Streptococcus pyogenes and E. coli O-111 with ED50 (mg/kg, subcutaneous) of 1.31, 8.13 and 67.2, respectively. Synonyms: L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[[(2E,4Z)-1-oxo-2,4-hexadien-1-yl]amino]-; L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[(1-oxo-2,4-hexadienyl)amino]-, (E,Z)-; Antibiotic TAN 749A. CAS No. 111337-86-1. Molecular formula: C15H27N5O3. Mole weight: 325.41. | |
| Sperabillin B | It is produced by the strain of Pseudomonas fluorescens YK-437. In vitro it has the effect of anti-pyomonas aeruginosa, alkali-producing faecal bacteria, acinetobacter calcium acetate and staphylococcus aureus. It also has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa resistant to methicillin, streptomycin, kanamycin, gentamicin, erythromycin, lincomycin, etc. It is used in mice infected with Staphylococcus aureus, Streptococcus pyogenes and E. coli O-111 with ED50 (mg/kg, subcutaneous) of 0.35, 8.84 and 27.3, respectively. Synonyms: D-xylo-Heptonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6,7-pentadeoxy-6-((1-oxo-2,4-hexadienyl)amino)-, (E,Z)-; D-xylo-Heptonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6,7-pentadeoxy-6-[[(2E,4Z)-1-oxo-2,4-hexadienyl]amino]-; Antibiotic TAN 749B. CAS No. 111337-85-0. Molecular formula: C16H29N5O3. Mole weight: 339.43. | |
| Sperabillin C | It is produced by the strain of Pseudomonas fluorescens YK-437. In vitro it has the effect of anti-pyomonas aeruginosa, alkali-producing faecal bacteria, acinetobacter calcium acetate and staphylococcus aureus. It also has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa resistant to methicillin, streptomycin, kanamycin, gentamicin, erythromycin, lincomycin, etc. It is used in mice infected with Staphylococcus aureus and E. coli O-111 with ED50 (mg/kg, subcutaneous) of 12.5 and 50, respectively. Synonyms: L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[[(2E,4E)-1-oxo-2,4-hexadien-1-yl]amino]-; L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[(1-oxo-2,4-hexadienyl)amino]-, (E,E)-; Antibiotic TAN 749C. CAS No. 111337-84-9. Molecular formula: C15H27N5O3. Mole weight: 325.41. | |
| Sperabillin D | It is produced by the strain of Pseudomonas fluorescens YK-437. In vitro it has the effect of anti-pyomonas aeruginosa, alkali-producing faecal bacteria, acinetobacter calcium acetate and staphylococcus aureus. It also has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa resistant to methicillin, streptomycin, kanamycin, gentamicin, erythromycin, lincomycin, etc. It is used in mice infected with Staphylococcus aureus and E. coli O-111 with ED50 (mg/kg, subcutaneous) of 1.82 and 55.9, respectively. Synonyms: D-xylo-Heptonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6,7-pentadeoxy-6-[[(2E,4E)-1-oxo-2,4-hexadien-1-yl]amino]-; D-xylo-Heptonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6,7-pentadeoxy-6-((1-oxo-2,4-hexadienyl)amino)-, (E,E)-; Antibiotic TAN 749D. CAS No. 111465-40-8. Molecular formula: C16H29N5O3. Mole weight: 339.43. | |
| T5342126 | T-5342126 is a toll-like receptor 4 (TLR4) antagonist. It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells ( IC 50 =27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isolated human whole blood ( IC 50 s=110.5, 315.6, and 318.4 μM, respectively). T-5342126 (82 mg/kg) reduces ethanol intake and the abundance of ionized calcium-binding adapter molecule 1 (Iba1), a marker of microglial activation, in the central nucleus of the amygdala in ethanol-dependent mice. Uses: Scientific research. Group: Signaling pathways. CAS No. 956507-49-6. Pack Sizes: 1 mg (21.83 mM * 100 μL in Methyl acetate); 5 mg (21.83 mM * 500 μL in Methyl acetate); 10 mg (21.83 mM * 1 mL in Methyl acetate). Product ID: HY-123789. | |
| Urantide acetate | Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3) that blocks hU-II-induced contractions in the thoracic aorta ex vivo. Urantide has no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Urantide also exhibits partial agonist activity in a calcium mobilization assay (in CHO cells expressing hUT receptors). Synonyms: L-Valine, L-α-aspartyl-3-mercapto-L-valyl-L-phenylalanyl-D-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-, cyclic (2?7)-disulfide, acetate salt (1:1); H-Asp-Pen(1)-Phe-D-Trp-Orn-Tyr-Cys(1)-Val-OH.CH3CO2H; L-alpha-aspartyl-L-penicillamyl-L-phenylalanyl-D-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-L-valine (2->7)-disulfide acetic acid; (S)-4-(((4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-10-(3-aminopropyl)-16-benzyl-4-(((S)-1-carboxy-2-methylpropyl)carbamoyl)-7-(4-hydroxybenzyl)-20,20-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl)amino)-3-amino-4-oxobutanoic acid compound with acetic acid (1:1). Grades: ≥95%. Molecular formula: C53H70N10O14S2. Mole weight: 1135.32. | |
| Urotensin II (114-124), human acetate | Urotensin II (human) is an endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Urotensin II (human) increases calcium levels in a concentration-dependent manner in HEK293 cells expressing human UTR (EC50 = 0.6 nM), and causes arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo. Synonyms: L-Valine, L-α-glutamyl-L-threonyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (5?10)-disulfide acetate; Human UII acetate; Human urotensin II acetate; Urotensin II (human) acetate; H-Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH.CH3CO2H (Disulfide bridge: Cys5-Cys10); L-alpha-glutamyl-L-threonyl-L-prolyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (5->10)-disulfide acetic acid. Grades: ≥95%. Molecular formula: C66H89N13O20S2. Mole weight: 1448.63. | |
| Ziconotide acetate | Ziconotide acetate (SNX-111 acetate), a peptide, is a potent and selective block of N-type calcium channels antagonist. Ziconotide acetate reduces synaptic transmission, and can be used for chronic pain research [1]. Uses: Scientific research. Group: Peptides. Alternative Names: SNX-111 acetate. CAS No. 914454-03-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0062B. | |
| Ziconotide Polyacetate | Α selective antagonist of N-type voltage sensitive calcium channels (VSCC). Blocks neurotransmitter release by preventing depolarization-induced calcium influx. Used as a ligand for binding studies of voltage sensitive calcium channels. Analgesic; neuroprotective. Group: Biochemicals. Alternative Names: ω-Conotoxin M VIIA Acetate; ω-Conopeptide MVIIA Acetate; Prialt Acetate; SNX 111. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| 1-Methyl-1H-imidazole-2-acetic Acid-d3 Hydrochloride | 1-Methyl-1H-imidazole-2-acetic Acid-d3 Hydrochloride is the isotope labelled analog of 1-Methyl-1H-imidazole-2-acetic Acid Hydrochloride. 1-Methyl-1H-imidazole-2-acetic Acid Hydrochloride is an intermediate in the synthesis of heterocyclylalkylidene diphosphonic acids as calcium metabolism regulators. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C6H6D3ClN2O2, Molecular Weight: 179.62. US Biological Life Sciences. | Worldwide |
| 1-Methyl-1H-imidazole-2-acetic Acid Hydrochloride | 1-Methyl-1H-imidazole-2-acetic Acid Hydrochloride is an intermediate in the synthesis of heterocyclylalkylidene diphosphonic acids as calcium metabolism regulators. Group: Biochemicals. Grades: Highly Purified. CAS No. 131654-57-4. Pack Sizes: 100mg, 1g. Molecular Formula: C6H9ClN2O2, Molecular Weight: 176.6. US Biological Life Sciences. | Worldwide |
| 1-Oleoyl-2-acetyl-sn-glycerol | 1-Oleoyl-2-acetyl-sn glycerol is a synthetic, cell permeable diacylglycerol analog. 1-Oleoyl-2-acetyl-sn glycerol activates calcium-dependent protein kinase C (PKC) and induces the superoxide-production. Uses: Scientific research. Group: Signaling pathways. CAS No. 86390-77-4. Pack Sizes: 5 mg (25.09 mM * 500 μL in Acetonitrile); 10 mg (25.09 mM * 1 mL in Acetonitrile); 25 mg (25.09 mM * 2.5 mL in Acetonitrile). Product ID: HY-131648. | |
| (2E)-2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene]-acetic Acid Ethyl Ester Hydrochloride | (2E)-2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene]-acetic Acid Ethyl Ester Hydrochloride is an intermediate in the synthesis of trans R-138727, (Prasugrel Metabolite) (R070195), which is the active metabolite of Prasugrel; inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: influence of other blood cells, calcium, and aspirin. Group: Biochemicals. Grades: Highly Purified. CAS No. 204206-07-5. Pack Sizes: 500ug, 1mg. Molecular Formula: C20H24FNO3S; (HCl), Molecular Weight: 377.473645999999. US Biological Life Sciences. | Worldwide |
| (2E)-[4-Bromo-1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-3-piperidinylidene]-acetic Acid Ethyl Ester | (2E)-[4-Bromo-1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-3-piperidinylidene]-acetic Acid Ethyl Ester is an intermediate in the synthesis of trans R-138727, (Prasugrel Metabolite) (R070195), which is the active metabolite of Prasugrel; inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: influence of other blood cells, calcium, and aspirin. Group: Biochemicals. Grades: Highly Purified. CAS No. 239466-57-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C20H23BrFNO3, Molecular Weight: 424.3. US Biological Life Sciences. | Worldwide |
| (2Z) -[ (1R, 4R, 6S) -4-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-1-methyl-7-oxabicyclo[4. 1. 0]hept-2-ylidene]-acetic Acid Ethyl Ester | (2Z) -[ (1R, 4R, 6S) -4-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-1-methyl-7-oxabicyclo[4. 1. 0]hept-2-ylidene]-acetic Acid Ethyl Ester is an intermediate used in the synthesis of Calcitriol-d6 (C144502), which is the biologically active form of vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 326496-94-0. Pack Sizes: 250mg, 500mg. Molecular Formula: C17H30O4Si, Molecular Weight: 326.5. US Biological Life Sciences. | Worldwide |
| 3-Acetoxy-2-oxopropanol-13C2 Dimer | 3-Acetoxy-2-oxopropanol-13C2 Dimer is the isotope labelled analog of 3-Acetoxy-2-oxopropanol Dimer (A167630); a dimer of 3-acetoxy-2-oxopropanol and a derivative of 1,3-Dihydroxyacetone Dimer (D450075) which is a compound used in the synthesis of dihydropyrimidine calcium channel blockers. 1,3-Dihydroxyacetone Dimer is also used in the preparation of new antineoplastic and antifilarial agents. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C613C4H16O8, Molecular Weight: 268.2. US Biological Life Sciences. | Worldwide |
| 3-Acetoxy-2-oxopropanol Dimer | 3-Acetoxy-2-oxopropanol Dimer is the dimer of 3-acetoxy-2-oxopropanol and a derivative of 1,3-Dihydroxyacetone Dimer (D450075); a compound used in the synthesis of dihydropyrimidine calcium channel blockers. 1,3-Dihydroxyacetone Dimer is also used in the preparation of new antineoplastic and antifilarial agents. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 5g. Molecular Formula: C10H16O8, Molecular Weight: 264.23. US Biological Life Sciences. | Worldwide |
| 3-(Acetylmethylamino)-1-propanesulfonic Acid Calcium Salt | 3-(Acetylmethylamino)-1-propanesulfonic Acid Calcium Salt is an impurity of acamprosate (A120000). Acamprosate (A120000) is a synthetic amino acid and a neurotransmitter analogue that is used as an alcohol deterrent in management of alcohol dependence and abuse. Acamprosate was approved for use in the therapy of alcohol dependence and abuse in the United States in 2004. Group: Biochemicals. Grades: Highly Purified. CAS No. 233591-26-9. Pack Sizes: 250mg, 2.5g. Molecular Formula: C12H26CaN2O8S2, Molecular Weight: 428.18. US Biological Life Sciences. | Worldwide |
| 3-(Acetylmethylamino)-1-propanesulfonic Acid Calcium Salt-d6 | 3-(Acetylmethylamino)-1-propanesulfonic Acid Calcium Salt-d6 is the isotope labelled analog of 3-(Acetylmethylamino)-1-propanesulfonic Acid Calcium Salt. 3-(Acetylmethylamino)-1-propanesulfonic Acid Calcium Salt is an impurity of acamprosate (A120000). Acamprosate (A120000) is a synthetic amino acid and a neurotransmitter analogue that is used as an alcohol deterrent in management of alcohol dependence and abuse. Acamprosate was approved for use in the therapy of alcohol dependence and abuse in the United States in 2004. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C12D6H20CaN2O8S2, Molecular Weight: 434.24. US Biological Life Sciences. | Worldwide |
| 3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-methyl-1,5-benzothiazepin-4(5H)-one | 3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-methyl-1,5-benzothiazepin-4(5H)-one is an impurity of Diltiazem (D460620), a calcium channel blocker with vasodilating activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 2067323-40-2. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H19NO4S, Molecular Weight: 357.42. US Biological Life Sciences. | Worldwide |
| A-740003 | A-740003 is potent, selective and competitive P2X7 receptor antagonist. Its IC50 values are 18 and 40 nM for rat and human receptors respectively measured by agonist-stimulated changes in intracellular calcium concentrations. It displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 μM. It reduces nociception in animal models of persistent neuropathic and inflammatory pain. It showed weak or no activity (IC(50) > 10 muM) at other P2 receptors and an array of other neurotransmitter and peptide receptors, ion channels, reuptake sites, and enzymes. It potently blocked agonist-evoked IL-1beta release (IC(50) = 156 nM) and pore formation (IC(50) = 92 nM) in differentiated human THP-1 cells. It produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Uses: A-740003 produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Synonyms: A-740003; A 740003; A740003; N-[1-[[(Cyanoamino)(5-quinolinylimino)methyl]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide;N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide. Grades: >98 %. CAS No. 861393-28-4. Molecular formula: C26H30N6O3. Mole weight: 474.55. | |
| Acamprosate calcium | Acamprosate calcium(Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Calcium N-acetylhomotaurinate. CAS No. 77337-73-6. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-17030. | |
| Acamprosate Calcium | Acamprosate calcium is a gamma-aminobutyric acid(GABA)agonist and modulator of glutamatergic systems. It has been used in alcohol dependence treatments and may be an effective augmentation therapy in patients with treatment-resistant anxiety. It has low bioavailability, but also has an excellent tolerability and safety profile. It is unique in that it is not metabolized by the liver and is also not impacted by alcohol use, so it can be administered to patients with hepatitis or liver disease and to patients who continue drinking alcohol. It was approved for use in the therapy of alcohol dependence and abuse in the United States in 2004. Uses: Alcohol deterrents. Synonyms: Calcium 3-acetamidopropane-1-sulfonate; Calcium 3-(acetylamino)propanesulphonate; 3-(Acetylamino)-1-propanesulfonic Acid Calcium Salt; Calcium Acetylhomotaurine; Alcomed; Sobriol; Aotal calcium; Calcium N-acetylhomotaurinate. Grades: >98.0%. CAS No. 77337-73-6. Molecular formula: C10H20CaN2O8S2. Mole weight: 400.48. | |
| Acamprosate Calcium (3-(Acetylamino)-1-propanesulfonic Acid Calcium Salt, Calcium Acetylhomotaurine. ) | Of interest for the treatment of alcoholism. Group: Biochemicals. Alternative Names: 3-(Acetylamino)-1-propanesulfonic Acid Calcium Salt, Calcium Acetylhomotaurine. Grades: Highly Purified. CAS No. 77337-73-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Acamprosate-d6 Calcium (Calcium Acetylhomotaurinate-d6) | Of interest for the treatment of alcoholism. Group: Biochemicals. Alternative Names: Calcium Acetylhomotaurinate-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Acecainide HCl | Acecainide, also known as N-acetylprocainamide and ASL 601, is a class III antiarrhythmic compound. It increases the duration of the action potential by decreasing the delayed outward potassium current, slightly decreasing the calcium current, and slightly depressing the inward rectifier potassium current. Acecainide can be given either intravenously or orally, and is eliminated primarily by renal excretion. Synonyms: 4'- ( (2- (Diethylamino) ethyl) carbamoyl) acetanilide monohydrochloride; Acecainide; N-acetylprocainamide, ASL 601; ASL-601; ASL601. CAS No. 34118-92-8. Molecular formula: C15H24ClN3O2. Mole weight: 313.82. | |
| Acetylaconitine | Acetylaconitine is a diterpenoid alkaloid that is extracted from the roots of aconite plants. It has been used as a medicine for centuries in China and Japan. Acetylaconitine has shown anti-inflammatory properties and has been used clinically to treat inflammatory diseases, such as cancer and arthritis. Acetylaconitine binds to fatty acids, which may be due to its unsaturated alkyl chain. Acetylaconitine also blocks the action of calcium ions on cells, preventing them from releasing histamine. This drug also blocks the synthesis of prostaglandins by inhibiting cyclooxygenase activity in the cell membrane. Acetylaconitine is toxic to humans and animals because it inhibits respiration by blocking cellular respiration at mitochondria level. Group: Other alkaloids. CAS No. 77181-26-1. Molecular formula: C36H49NO12. Mole weight: 687.77 g/mol. Canonical SMILES: CCN1C[C@@]2 ([C@@H] (C[C@@H] ([C@@]34[C@@H]2[C@H] ([C@@H] (C31)[C@@]5 ([C@@H]6[C@H]4C[C@@] ([C@@H]6OC (=O)C7=CC=CC=C7) ([C@H] ([C@@H]5O)OC)O)OC (=O)C)OC)OC)OC (=O)C)COC. Catalog: ACM77181261. | |
| Acetyl-Heme-Binding Protein 1 (1-21) (human) | Acetyl-Heme-Binding Protein 1 (1-21) (human), an acetylated peptide corresponding to the N-terminal fragment of human heme-binding protein, specifically promotes calcium mobilization and chemotaxis in dendritic cells and monocytes via the FPR-like receptor 2 (FPRL 2). In neutrophils, it inhibits FPR and FPRL1-mediated signaling. Synonyms: F2L; Ac-Met-Leu-Gly-Met-Ile-Lys-Asn-Ser-Leu-Phe-Gly-Ser-Val-Glu-Thr-Trp-Pro-Trp-Gln-Val-Leu-OH; N-acetyl-L-methionyl-L-leucyl-glycyl-L-methionyl-L-isoleucyl-L-lysyl-L-asparagyl-L-seryl-L-leucyl-L-phenylalanyl-glycyl-L-seryl-L-valyl-L-alpha-glutamyl-L-threonyl-L-tryptophyl-L-prolyl-L-tryptophyl-L-glutaminyl-L-valyl-L-leucine. Grades: ≥95%. CAS No. 946571-77-3. Molecular formula: C116H176N26O30S2. Mole weight: 2478.96. | |
| Aladorian | Aladorianis is a ryanodine receptor calcium release channel modulator. It is an antiarrhythmic agent. Clinical development for Chronic heart failure and Ventricular tachycardia was discontinued. Uses: Chronic heart failure; ventricular tachycardia. Synonyms: 2,3-Dihydro-7-methoxy-α-oxo-1,4-benzothiazepine-4(5H)-acetic Acid; ARM036; ARM-036; ARM 036; S36; S44121-1; Aladorian; Aladorian; S 36; S 44121-1. Grades: 98%. CAS No. 865433-00-7. Molecular formula: C12H13NO4S. Mole weight: 267.30. | |
| alcohol dehydrogenase (quinone) | Only described in acetic acid bacteria where it is involved in acetic acid production. Associated with membrane. Electron acceptor is membrane ubiquinone. A model structure suggests that, like all other quinoprotein alcohol dehydrogenases, the catalytic subunit has an 8-bladed propeller structure, a calcium ion bound to the PQQ in the active site and an unusual disulfide ring structure in close proximity to the PQQ; the catalytic subunit also has a heme c in the C-terminal domain. The enzyme has two additional subunits, one of which contains three molecules of heme c. It does not require amines for activation. It has a restricted substrate specificity, oxidizing a few primary alcohols (C2 to C6), but not methanol, secondary alcohols and some aldehydes. It is assayed with phenazine methosulfate or with ferricyanide. Group: Enzymes. Synonyms: type III ADH; membrane associated quinohaemoprotein alcohol dehydrogenase. Enzyme Commission Number: EC 1.1.5.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0433; alcohol dehydrogenase (quinone); EC 1.1.5.5; type III ADH; membrane associated quinohaemoprotein alcohol dehydrogenase. Cat No: EXWM-0433. | |
| Ani 9 | Ani 9 is a highly selective and potent anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A) inhibitor with IC50 value of 77 nM. It completely inhibits ANO1 chloride current with submicromolar potency and displays no effect on ANO2 activity at 10 μM. It does not affect the intracellular calcium signaling, or CFTR chloride channel activity and ENaC channel activity at 30 μM. It may be a useful pharmacological tool for studying ANO1. It may be potential for drug therapy of hypertension, cancer, diarrhea, asthma and pain. Synonyms: Ani9; Ani-9; Ani 9; (4-Chloro-2-methylphenoxy)-acetic acid [(2-methoxyphenyl)methylene]hydrazide; 2-(4-Chloro-2-methylphenoxy)-N-[(2-methoxyphenyl)methylideneamino]-acetamide; 2-(4-Chloro-2-methylphenoxy)-acetic acid 2-[(2-methoxyphenyl)methylene]hydrazide; 2-(4-Chloro-2-methylphenoxy)-N'-(2-methoxybenzylidene)acetohydrazide. Grades: ≥98% by HPLC. CAS No. 356102-14-2. Molecular formula: C17H17ClN2O3. Mole weight: 332.78. | |
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