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1g Pack Size. Group: Building Blocks, Organics. Formula: C4H5CaNO4. CAS No. 21059-46-1. Prepack ID 90027553-1g. Molecular Weight 171.16. See USA prepack pricing.
Amlodipine aspartic acid impurity
Amlodipine Aspartic Acid Impurity is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: Amlodipine Aspartate; L-Aspartate Amlodipine; (2-((4-(2-Chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2-yl)methoxy)ethyl)aspartic acid; Amlodipine Impurity 24. Grades: ≥95%. CAS No. 400602-35-9. Molecular formula: C24H29ClN2O9. Mole weight: 524.95.
Aspartic acid calcium
Aspartic acid calcium (Calcium L-aspartate) is a chelate where calcium is attached to an amino acid naming L-Aspartic acid. L-Aspartic acid is an amino acid and serves as a building block for proteins in the body. Uses: Scientific research. Group: Natural products. Alternative Names: Calcium L-aspartate. CAS No. 10389-09-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N0666B.
Aspartic acid calcium
Aspartic acid calcium is a chelate where calcium is attached to L-Aspartic acid, an amino acid that is used in the biosynthesis of proteins. Synonyms: calcium;(2S)-2-aminobutanedioate; (+-)-Aspartic Acid; (R,S)-Aspartic Acid; Ammonium Aspartate; Aspartate. CAS No. 21059-46-1. Molecular formula: C4H5CaNO4. Mole weight: 171.16.
L-Aspartic Acid Calcium Salt Hydrochloride
L-Aspartic Acid salcium salt is used in three high-dose oral calcium salts model (CaCO3, CaCl2, Ca-aspartate-hydrochloride) which has effects on acid-base metabolism, plasma electrolytes and urine parameters in rats. Group: Biochemicals. Alternative Names: L-Aspartic Acid Calcium Salt Hydrochloride; CalciumAspartate Hydrochloride. Grades: Highly Purified. CAS No. 92533-40-9. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Asp-26-Calcitonin
Asp-26-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bond between Cys1 and Cys7); L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-α-aspartyl-L-threonyl-glycyl-L-seryl-glycyl-L-threonyl-L-prolinamide (1->7)-disulfide. Molecular formula: C145H239N43O49S2. Mole weight: 3432.88.
Asp(3)-Calcitonin
Asp(3)-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asp-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bond between Cys1 and Cys7); L-cysteinyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-glycyl-L-threonyl-L-prolinamide (1->7)-disulfide. Molecular formula: C145H239N43O49S2. Mole weight: 3432.88.
(Asp76)-pTH (39-84) (human)
Asp76-pTH (39-84) (human) is a synthetic peptide widely utilized in the biomedical sector exhibiting its prowess as a potent receptor antagonist for parathyroid hormone (PTH), exerting pivotal influence over the intricate dynamics of calcium and phosphate metabolism. Synonyms: H-Ala-Pro-Leu-Ala-Pro-Arg-Asp-Ala-Gly-Ser-Gln-Arg-Pro-Arg-Lys-Lys-Glu-Asp-Asn-Val-Leu-Val-Glu-Ser-His-Glu-Lys-Ser-Leu-Gly-Glu-Ala-Asp-Lys-Ala-Asp-Val-Asp-Val-Leu-Thr-Lys-Ala-Lys-Ser-Gln-OH; 39-84-Parathormone (human); L-Alanyl-L-prolyl-L-leucyl-L-alanyl-L-prolyl-L-arginyl-L-α-aspartyl-L-alanylglycyl-L-seryl-L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-lysyl-L-lysyl-L-α-glutamyl-L-α-aspartyl-L-asparaginyl-L-valyl-L-leucyl-L-valyl-L-α-glutamyl-L-seryl-L-histidyl-L-α-glutamyl-L-lysyl-L-seryl-L-leucylglycyl-L-α-glutamyl-L-alanyl-L-α-aspartyl-L-lysyl-L-alanyl-L-α-aspartyl-L-valyl-L-α-aspartyl-L-valyl-L-leucyl-L-threonyl-L-lysyl-L-alanyl-L-lysyl-L-seryl-L-glutamine; human parathormone (39-84). Grades: ≥95% by HPLC. CAS No. 79804-72-1. Molecular formula: C211H356N66O73. Mole weight: 4985.55.
Aspartic Acid
Aspartic Acid. Synonyms: L- aminosuccinic acid; L-Aspartic Acid. CAS No. 56-84-8. Product ID: PE-0423. Molecular formula: C4H7NO4. Mole weight: 133.1. Category: Flavoring agent; Carrier Excipients. Product Keywords: Pharmaceutical Excipients; Other Materials; Aspartic Acid; Carrier Excipients; Flavoring agent; Carrier Excipients; C4H7NO4; 56-84-8; 56-84-8. UNII: 30KYC7MIAI. Grade: Pharmceutical Excipients. Administration route: Intravenous injection. Dosage Form: Intravenous injection. Stability and Storage Conditions: Store in a cool and dry place in an airtight container. Source and Preparation: This product is naturally found in various animal and plant proteins, especially in beet molasses. Commercially available products are usually made by hydrolyzing various proteins rich in the product with acid, neutralizing them with calcium hydroxide to form calcium salts, and then separating them. It can also be prepared by enzyme addition of ammonia to fumaric acid. Safety: This product is a natural nutrient, non-toxic and generally recognized as safe.
Aspartocin D
Aspartocin D is a minor analogue of the amphomycin complex, a family of lipopeptide antibiotic produced by Streptomyces canus. Aspartocin D has the activity against Gram-positive bacteria with MIC of 0.125 μg/ml for B. subtilis and is presumed to act by inhibiting bacterial cell wall peptidoglycan synthesis, however its bioprofile and potential utility has not been extensively investigated. The antibacterial activity is calcium-dependent, with MICs ranging from 0.06-4 and 0.25-8 μg/ml for B. subtilis and S. aureus, respectively, in the presence of higher (2.5 mM) to lower (0.125 mM) calcium concentrations. Synonyms: N-[(3Z)-9-methyl-1-oxo-3-decen-1-yl]-L-alpha-aspartyl-(2S,3R)-2,3-diaminobutanoyl-(2R)-2-piperidinecarbonyl-(3S)-3-methyl-L-alpha-aspartyl-L-alpha-aspartylglycyl-L-alpha-aspartylglycyl-(2R,3R)-2,3-diaminobutanoyl-L-valyl-L-proline(11?2)-lactam. Grades: ≥95% by HPLC. CAS No. 1562369-96-3. Molecular formula: C56H87N13O20. Mole weight: 1262.37.
ATI-2341 acetate
ATI-2341 acetate is a potent and functionally selective CXCR4 allosteric agonist that activates Gα1 rather than Gα13. ATI-2341 acetate activates the inhibitory heterotrimer G protein (GI) to promote the inhibition of cAMP production and induce calcium mobilization. Synonyms: palmitoyl-Met-Gly-Tyr-Gln-Lys-Lys-Leu-Arg-Ser-Met-Thr-Asp-Lys-Tyr-Arg-Leu-OH.CH3CO2H; N-palmitoyl-L-methionyl-glycyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-lysyl-L-leucyl-L-arginyl-L-seryl-L-methionyl-L-threonyl-L-alpha-aspartyl-L-lysyl-L-tyrosyl-L-arginyl-L-leucine acetic acid; N-(1-Oxohexadecyl)-L-methionylglycyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-lysyl-L-leucyl-L-arginyl-L-seryl-L-methionyl-L-threonyl-L-α-aspartyl-L-lysyl-L-tyrosyl-L-arginyl-L-leucine acetate; ATI 2341 acetate; ATI2341 acetate. Grades: ≥95%. Molecular formula: C106H182N26O27S2. Mole weight: 2316.87.
Autocamtide 2
Autocamtide 2 is a highly selective synthetic peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay. Synonyms: Autocamtide II; H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH; L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-alpha-glutamyl-L-threonyl-L-valyl-L-alpha-aspartyl-L-alanyl-L-leucine. Grades: ≥95%. CAS No. 129198-88-5. Molecular formula: C65H118N22O20. Mole weight: 1527.77.
Autocamtide 2 TFA
Autocamtide 2 TFA is a highly selective synthetic peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay. Synonyms: H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH.TFA; L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-alpha-glutamyl-L-threonyl-L-valyl-L-alpha-aspartyl-L-alanyl-L-leucine trifluoroacetic acid; Autocamtide 2 trifluoroacetate salt. Grades: ≥95%. Molecular formula: C67H119F3N22O22. Mole weight: 1641.79.
Calcitonin (rat)
Calcitonin, a peptide hormone involved in calcium and bone metabolism, is effective in treating hypercalcemia caused by bone metastasis, multiple myeloma and osteitis malformation, and is also effective against osteoporosis. Synonyms: H-Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Leu-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ser-Ile-Gly-Val-Gly-Ala-Pro-NH2 (Disulfide bridge: Cys1-Cys7); L-cysteinyl-glycyl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-methionyl-L-leucyl-glycyl-L-threonyl-L-tyrosyl-L-threonyl-L-glutaminyl-L-alpha-aspartyl-L-leucyl-L-asparagyl-L-lysyl-L-phenylalanyl-L-histidyl-L-threonyl-L-phenylalanyl-L-prolyl-L-glutaminyl-L-threonyl-L-seryl-L-isoleucyl-glycyl-L-valyl-glycyl-L-alanyl-L-prolinamide (1->7)-disulfide. Grades: ≥95%. CAS No. 11118-25-5. Molecular formula: C148H228N40O46S3. Mole weight: 3399.83.
C-Type Natriuretic Peptide (CNP) (1-22), human
C-type natriuretic peptide is an endogenous peptide found in plasma and cerebrospinal fluid. It is composed of 22 amino acids. C-type natriuretic peptide acts as an agonist of natriuretic peptide receptor NPR2 (NPRB) and exhibits affinity for NPR3 (NPRC). It inhibits L-type calcium currents in myocytes and exhibits antiproliferative effects in cardiac fibroblasts in vitro. Regulates cartilage homeostasis, body fluid volume and exhibits vasodilatory activity in vivo. Synonyms: H-Gly-Leu-Ser-Lys-Gly-Cys(1)-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys(1)-OH; glycyl-L-leucyl-L-seryl-L-lysyl-glycyl-L-cysteinyl-L-phenylalanyl-glycyl-L-leucyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-seryl-L-methionyl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteine (6->22)-disulfide; Natriuretic peptide, C-type; C-type natriuretic peptide (1-22) (human, rat, swine); Atriopeptin C (pig); C-Type Natriuretic Peptide (32-53) (human, porcine, rat). Grades: ≥95%. CAS No. 127869-51-6. Molecular formula: C93H157N27O28S3. Mole weight: 2197.60.
Gastrin I (human) acetate
Gastrin I (human) acetate, an endogenous peptide produced by the stomach, is a selective CCK2 receptor agonist that stimulates gastric acid secretion in vivo and increases cytoplasmic calcium levels in isolated rabbit gastric parietal cells (EC50 = 11 nM). Synonyms: Little gastrin I acetate; Gastrin-17 acetate; H-Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2.CH3CO2H; Gastrin-17 I (human) acetate; 5-Oxo-L-prolylglycyl-L-prolyl-L-tryptophyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-tyrosylglycyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide acetate; Human gastrin heptadecapeptide I acetate; Human gastrin I (1-17) acetate. Grades: ≥95%. Molecular formula: C99H128N20O33S. Mole weight: 2158.25.
Katacalcin
Katacalcin is a second potent plasma calcium-lowering peptide that may be a useful marker for the detection of medullary thyroid carcinoma. Uses: Calcium-regulating hormones and agents. Synonyms: PDN 21; H-Asp-Met-Ser-Ser-Asp-Leu-Glu-Arg-Asp-His-Arg-Pro-His-Val-Ser-Met-Pro-Gln-Asn-Ala-Asn-OH; L-alpha-aspartyl-L-methionyl-L-seryl-L-seryl-L-alpha-aspartyl-L-leucyl-L-alpha-glutamyl-L-arginyl-L-alpha-aspartyl-L-histidyl-L-arginyl-L-prolyl-L-histidyl-L-valyl-L-seryl-L-methionyl-L-prolyl-L-glutaminyl-L-asparagyl-L-alanyl-L-asparagine; Calcitonin C-Terminal Flanking Peptide (human). Grades: ≥95%. CAS No. 85916-47-8. Molecular formula: C97H154N34O36S2. Mole weight: 2436.59.
Lei-Dab 7
HLei-Dab 7 is a calcium-activated potassium channel blocker. Synonyms: L-alanyl-L-phenylalanyl-L-cysteinyl-L-asparaginyl-L-leucyl-L-arginyl-(2S)-2,4-diaminobutanoyl-L-cysteinyl-L-glutaminyl-L-leucyl-L-seryl-L-cysteinyl-L-arginyl-L-seryl-L-leucylglycyl-L-leucyl-L-leucylglycyl-L-lysyl-L-cysteinyl-L-isoleucylglycyl-L-α-aspartyl-L-lysyl-L-cysteinyl-L-α-glutamyl-L-cysteinyl-L-valyl-L-lysyl-L-Histidinamide-cyclic (3?21)-(8?26)-(12?28)-tris(disulfide). Grades: ≥97%. CAS No. 1061556-49-7. Molecular formula: C141H236N46O39S6. Mole weight: 3392.06.
Native Leuconostoc mesenteroides Dextran Sucrase
Dextransucrases are glucansucrases that are able to produce dextran, a glucose polymer linked mainly through α1-6 bonds. However, α1-3, α1-6, α1-4 and α1-2 bonds are also found, in both the main chain and the branching linkages. The peptide has approximately 1600 amino acids. The aspartic acid in position 551 is essential for catalytic activity, while glutamic acid 589 and aspartic acid 662 complement the catalytic triad. The activity of dextransucrase is decreased by EDTA, and is restored by the addition of calcium ions. Zinc, cadmium, lead, mercury and copper ions are inhibitory to various degrees. Applications: Dextran sucrase from leu... immobilized sphere for the production of dextran from sucrose. Group: Enzymes. Synonyms: EC 2.4.1.5, sucrose 6-glucosyltransferase; SGE; CEP; sucrose-1,6-α-glucan glucosyltransferase; sucrose:1,6-α-D-glucan 6-α-D-glucosyltransferase; 9032-14-8. Enzyme Commission Number: EC 2.4.1.5. CAS No. 9032-14-8. SGE. Activity: > 100 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing dextran, MES buffer salts and CaCl2. Source: Leuconostoc mesenteroides. EC 2.4.1.5, sucrose 6-glucosyltransferase; SGE; CEP; sucrose-1,6-α-glucan glucosyltransferase; sucrose:1,6-α-D-glucan 6-α-D-glucosyltransferase; 9032-14-8. Cat No: NATE-0669.
ω-agatoxin-IVA
ω-agatoxin-IVA (ω-AGA IVA) is a peptide originally isolated from funnel web-spider venom Agelenopsis aperta. This peptide is a specific blocker of P/Q-type calcium channel (Cav2.1). Synonyms: ω-Agatoxin IVa; H-Lys-Lys-Lys-Cys-Ile-Ala-Lys-Asp-Tyr-Gly-Arg-Cys-Lys-Trp-Gly-Gly-Thr-Pro-Cys-Cys-Arg-Gly-Arg-Gly-Cys-Ile-Cys-Ser-Ile-Met-Gly-Thr-Asn-Cys-Glu-Cys-Lys-Pro-Arg-Leu-Ile-Met-Glu-Gly-Leu-Gly-Leu-Ala-OH (Disulfide bridge: Cys4-Cys20, Cys12-Cys25, Cys19-Cys36, Cys27-Cys34); L-lysyl-L-lysyl-L-lysyl-L-cysteinyl-L-isoleucyl-L-alanyl-L-lysyl-L-alpha-aspartyl-L-tyrosyl-glycyl-L-arginyl-L-cysteinyl-L-lysyl-L-tryptophyl-glycyl-glycyl-L-threonyl-L-prolyl-L-cysteinyl-L-cysteinyl-L-arginyl-glycyl-L-arginyl-glycyl-L-cysteinyl-L-isoleucyl-L-cysteinyl-L-seryl-L-isoleucyl-L-methionyl-glycyl-L-threonyl-L-asparagyl-L-cysteinyl-L-alpha-glutamyl-L-cysteinyl-L-lysyl-L-prolyl-L-arginyl-L-leucyl-L-isoleucyl-L-methionyl-L-alpha-glutamyl-glycyl-L-leucyl-glycyl-L-leucyl-L-alanine (4->20),(12->25),(19->36),(27->34)-tetrakis(disulfide); SNX 290; ω-Aga-IV A; omega-Agatoxin IVA. Grades: ≥97%. CAS No. 145017-83-0. Molecular formula: C217H360N68O60S10. Mole weight: 5202.33.
Omega-conotoxin MVIIC
ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q and N-type calcium channels. Synonyms: ω-Conotoxin MVIIC; L-cysteinyl-L-lysyl-glycyl-L-lysyl-glycyl-L-alanyl-L-prolyl-L-cysteinyl-L-arginyl-L-lysyl-L-threonyl-L-methionyl-L-tyrosyl-L-alpha-aspartyl-L-cysteinyl-L-cysteinyl-L-seryl-glycyl-L-seryl-L-cysteinyl-glycyl-L-arginyl-L-arginyl-glycyl-L-lysyl-L-cysteinamide (1->16),(8->20),(15->26)-tris(disulfide); H-Cys-Lys-Gly-Lys-Gly-Ala-Pro-Cys-Arg-Lys-Thr-Met-Tyr-Asp-Cys-Cys-Ser-Gly-Ser-Cys-Gly-Arg-Arg-Gly-Lys-Cys-NH2 (Disulfide bridge: Cys1-Cys16, Cys8-Cys20, Cys15-Cys26); SNX-230. Grades: ≥97% by HPLC. CAS No. 147794-23-8. Molecular formula: C106H178N40O32S7. Mole weight: 2749.25.
Parathyroid hormone (1-34) (bovine)
Parathyroid hormone (1-34) (bovine) is a parathyroid hormone (PTH) receptor agonist. It increases calcium and inorganic phosphate levels in the serum of young rats. Parathyroid hormone (PTH) is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid, which is secreted by the chief cell of the parathyroid glands as a polypeptide containing 84 amino acids. Synonyms: L-Phenylalanine, L-alanyl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-phenylalanyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-seryl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-;; Ala-Val-Ser-Glu-Ile-Gln-Phe-Met-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe. CAS No. 12583-68-5. Molecular formula: C183H288N54O50S2. Mole weight: 4108.74.
pTH (1-37) (human)
pTH (1-37) (human) is a native bioactive fragment of pTH (1-84) (human) in circulation. Pulsatile rather than continuous administration of pTH (1-37) (human) can increase growth, bone calcium content and bone mineral density in uremic animals. Synonyms: Parathyrin (1-37) (human); H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-OH; L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparagyl-L-leucyl-glycyl-L-lysyl-L-histidyl-L-leucyl-L-asparagyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparagyl-L-phenylalanyl-L-valyl-L-alanyl-L-leucine. Grades: 95%. CAS No. 136799-54-7. Molecular formula: C195H316N58O54S2. Mole weight: 4401.15.
pTH (28-48) (human)
pTH (28-48) (human) is an ingenious and cutting-edge compoundexpressly designed and meticulously formulated to scrutinize the profound and intricate ramifications inflicted by the coveted parathyroid hormone (PTH) upon the exceptionally intricate and multifarious research of bone metabolism and calcium homeostasis. Synonyms: Parathyroid Hormone (28-48), human; H-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-Gly-Ala-Pro-Leu-Ala-Pro-Arg-Asp-Ala-Gly-Ser-OH; L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparagyl-L-phenylalanyl-L-valyl-L-alanyl-L-leucyl-glycyl-L-alanyl-L-prolyl-L-leucyl-L-alanyl-L-prolyl-L-arginyl-L-alpha-aspartyl-L-alanyl-glycyl-L-serine; Parathyroid Hormone Fragment 28-48 human. Grades: ≥95% by HPLC. CAS No. 83286-22-0. Molecular formula: C95H150N28O29. Mole weight: 2148.38.
SNX 482
SNX-482 has been isolated from the venom of the Spider Hysterocrates gigas (African tarantula). SNX-482 modulates the R-type current associated with the class α1E calcium channel (Cav2.3 from the CACNA1E gene). Synonyms: SNX-482; SNX482; H-Gly-Val-Asp-Lys-Ala-Gly-Cys(1)-Arg-Tyr-Met-Phe-Gly-Gly-Cys(2)-Ser-Val-Asn-Asp-Asp-Cys(3)-Cys(1)-Pro-Arg-Leu-Gly-Cys(2)-His-Ser-Leu-Phe-Ser-Tyr-Cys(3)-Ala-Trp-Asp-Leu-Thr-Phe-Ser-Asp-OH; glycyl-L-valyl-L-alpha-aspartyl-L-lysyl-L-alanyl-glycyl-L-cysteinyl-L-arginyl-L-tyrosyl-L-methionyl-L-phenylalanyl-glycyl-glycyl-L-cysteinyl-L-seryl-L-valyl-L-asparagyl-L-alpha-aspartyl-L-alpha-aspartyl-L-cysteinyl-L-cysteinyl-L-prolyl-L-arginyl-L-leucyl-glycyl-L-cysteinyl-L-histidyl-L-seryl-L-leucyl-L-phenylalanyl-L-seryl-L-tyrosyl-L-cysteinyl-L-alanyl-L-tryptophyl-L-alpha-aspartyl-L-leucyl-L-threonyl-L-phenylalanyl-L-seryl-L-aspartic acid (7->21),(14->26),(20->33)-tris(disulfide). Grades: >98%. CAS No. 203460-30-4. Molecular formula: C192H274N52O60S7. Mole weight: 4495.01.
Tigapotide
PCK3145 is a synthetic 15-mer peptide corresponding to amino acids 31-45 of the 94-amino acid isoform of human prostate secretory protein (PSP-94) with potential anti-metastasis and anti-angiogenesis activities. PSP-94-derived peptide PCK3145 may inhibit the secretion of the metastasis-related protein matrix metalloproteinase-9 (MMP-9) and its potential binding to its cell surface receptor CD44; may interfere with the vascular endothelial growth factor (VEGF) signaling pathway, resulting in an anti-angiogenesis effect; and may reduce the levels of parathyroid hormone-related protein (PTHrP), decreasing plasma calcium levels. PSP-94, one of three predominant proteins found in seminal fluid, may be down-regulated in prostate cancer, representing a potential survival mechanism for prostate cancer cells. MMP-9 is implicated in the invasion and metastasis of cancer. PTHrP may be expressed by various tumor cell types, resulting in the hypercalcemia of malignancy. Synonyms: PCK3145. Chemical name: L-Threonine, L-glutamyl-L-tryptophyl-L-glutaminyl-L-threonyl-L--aspartyl-L-asparaginyl-S-[(acetylamino)methyl]-L-cysteinyl-L-glutamyl-L-threonyl-S-[(acetylamino)methyl]-L-cysteinyl-L-threonyl-S-[(acetylamino)methyl]-L-cysteinyl-L-t. CAS No. 848084-83-3. Molecular formula: C82H119N21O34S3. Mole weight: 2039.15.
Urantide
Urantide is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3) that blocks hU-II induced contractions in thoracic aorta ex vivo. Urantide has no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Urantide also exhibits partial agonist activity in a calcium mobilization assay (in CHO cells expressing hUT receptors). Synonyms: L-Valine, L-α-aspartyl-3-mercapto-L-valyl-L-phenylalanyl-D-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-, cyclic (2?7)-disulfide; H-Asp-Pen(1)-Phe-D-Trp-Orn-Tyr-Cys(1)-Val-OH; L-alpha-aspartyl-L-penicillamyl-L-phenylalanyl-D-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-L-valine (2->7)-disulfide acetic acid; (S)-4-(((4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-10-(3-aminopropyl)-16-benzyl-4-(((S)-1-carboxy-2-methylpropyl)carbamoyl)-7-(4-hydroxybenzyl)-20,20-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl)amino)-3-amino-4-oxobutanoic acid. Grades: ≥95%. CAS No. 669089-53-6. Molecular formula: C51H66N10O12S2. Mole weight: 1075.26.
Urantide acetate
Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3) that blocks hU-II-induced contractions in the thoracic aorta ex vivo. Urantide has no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Urantide also exhibits partial agonist activity in a calcium mobilization assay (in CHO cells expressing hUT receptors). Synonyms: L-Valine, L-α-aspartyl-3-mercapto-L-valyl-L-phenylalanyl-D-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-, cyclic (2?7)-disulfide, acetate salt (1:1); H-Asp-Pen(1)-Phe-D-Trp-Orn-Tyr-Cys(1)-Val-OH.CH3CO2H; L-alpha-aspartyl-L-penicillamyl-L-phenylalanyl-D-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-L-valine (2->7)-disulfide acetic acid; (S)-4-(((4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-10-(3-aminopropyl)-16-benzyl-4-(((S)-1-carboxy-2-methylpropyl)carbamoyl)-7-(4-hydroxybenzyl)-20,20-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl)amino)-3-amino-4-oxobutanoic acid compound with acetic acid (1:1). Grades: ≥95%. Molecular formula: C53H70N10O14S2. Mole weight: 1135.32.
Urotensin II (114-124), human acetate
Urotensin II (human) is an endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Urotensin II (human) increases calcium levels in a concentration-dependent manner in HEK293 cells expressing human UTR (EC50 = 0.6 nM), and causes arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo. Synonyms: L-Valine, L-α-glutamyl-L-threonyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (5?10)-disulfide acetate; Human UII acetate; Human urotensin II acetate; Urotensin II (human) acetate; H-Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH.CH3CO2H (Disulfide bridge: Cys5-Cys10); L-alpha-glutamyl-L-threonyl-L-prolyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (5->10)-disulfide acetic acid. Grades: ≥95%. Molecular formula: C66H89N13O20S2. Mole weight: 1448.63.
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