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| Product | Description | |
|---|---|---|
| Capsaicin | 1g Pack Size. Group: Aroma Chemicals, Diagnostic Raw Materials, Research Organics & Inorganics, Testing Standards. Formula: C18H27NO3. CAS No. 404-86-4. Prepack ID 31397045-1g. Molecular Weight 305.41. See USA prepack pricing. |  |
| Capsaicin | Capsaicin ((E)-Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin has pain-relieving, antioxidant, anti-inflammatory, anti-cancer and certain neurotoxic effects [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (E)-Capsaicin. CAS No. 404-86-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10448. |  |
| Capsaicin | Capsaicin - Product ID: NST-10-110. Category: Alkaloids. Alternative Names: Adlea, Ausanil, Axsain, Capsaicine, Capsicin, Dolenon, Mioton, Ovocap, Qutenza, Zostrix. Purity: 98%. Test method: HPLC. CAS No. 404-86-4. Pack Sizes: 1g, 2g, 5g, 10g. Appearance: Off-white to yellowish Powder. Molecular formula: C18H27NO3. Mole weight: 305.41. Storage: +2 +8 °C. |  |
| Capsaicin | It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic. Group: Biochemicals. Alternative Names: (6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; trans-8-Methyl-N-vanillyl-6-nonenamide; Axsain; Mioton; Zacin; Zostrix. Grades: Highly Purified. CAS No. 404-86-4. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| Capsaicin, (6E)- | Capsaicin, (6E)-. Group: Biochemicals. CAS No. 404-86-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Capsaicin 99+% (GC) | Capsaicin 99+% (GC). Group: Biochemicals. Grades: GC. CAS No. 404-86-4. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Capsaicin-d3 | Capsaicin-d3. Group: Biochemicals. Alternative Names: (6E)-N-[(4-Hydroxy-3-methoxy-d3-phenyl)methyl]-8-methyl-6-nonenamide; trans-8-Methyl-N-vanillyl-6-nonenamide-d3; Axsain-d3; Mioton-d3; Zacin-d3; Zostrix-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Capsaicin-[d3] (E/Z-Mixture) | Capsaicin-[d3] (E/Z-Mixture) is the labelled analogue of Capsaicin, which is used as a tool in neurobiological research. It is a prototype vanilla-like receptor agonist and topical analgesic. Synonyms: Capsaicin-d3 (E/Z-Mixture); N-[(4-Hydroxy-3-(methoxy-d3)phenyl)methyl]-8-methyl-6-nonenamide; (E/Z)-8-Methyl-N-vanillyl-6-nonenamide-d3. Grade: ≥98% by HPLC; ≥99% atom D. CAS No. 1185237-43-7. Molecular formula: C18H24D3NO3. Mole weight: 308.44. |  |
| Capsaicin ≥97% (Single peak, HPLC) | Capsaicin ≥97% (Single peak, HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 404-86-4. Pack Sizes: 100mg, 250mg, 25mg, 1g. US Biological Life Sciences. | Worldwide |
| Capsaicin (Standard) | Capsaicin (Standard) is the analytical standard of Capsaicin. This product is intended for research and analytical applications. Capsaicin ((E)-Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin has pain relief, antioxidant, anti-inflammatory, neuroprotection and anti-cancer effects [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (E)-Capsaicin (Standard). CAS No. 404-86-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-10448R. | |
| 16,17-Dehydro capsaicin | 16,17-Dehydro capsaicin. Group: Biochemicals. Alternative Names: (6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6,8-nonadienamide. Grades: Highly Purified. CAS No. 509101-57-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H25NO3. US Biological Life Sciences. | Worldwide |
| 16,17-Dehydro Capsaicin | A dehydrogenated metabolite of Capsaicin. Synonyms: (6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6,8-nonadienamide. Grade: > 95%. CAS No. 509101-57-9. Molecular formula: C18H25NO3. Mole weight: 303.4. | |
| 16-Hydroxy Capsaicin | 16-Hydroxy Capsaicin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 112848-19-8. Molecular formula: C18H27NO4. Mole weight: 321.42. Catalog: APB112848198. |  |
| 16-Hydroxy Capsaicin | A metabolite of Capsaicin. Group: Biochemicals. Alternative Names: (6E)-8-Hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide. Grades: Highly Purified. CAS No. 112848-19-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C??H??NO?, Molecular Weight: 321.41. US Biological Life Sciences. | Worldwide |
| 16-Hydroxy Capsaicin | A metabolite of Capsaicin. Synonyms: (6E)-8-Hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide. Grade: > 95%. CAS No. 112848-19-8. Molecular formula: C18H27NO4. Mole weight: 321.42. | |
| 17-Hydroxy capsaicin | 17-Hydroxy capsaicin. Group: Biochemicals. Alternative Names: (6E)-9-Hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; ω-Hydroxycapsaicin. Grades: Highly Purified. CAS No. 69173-71-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H27NO4. US Biological Life Sciences. | Worldwide |
| 17-Hydroxy Capsaicin | A metabolite of Capsaicin. Synonyms: (6E)-9-Hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; ω-Hydroxycapsaicin. Grade: > 95%. CAS No. 69173-71-3. Molecular formula: C18H27NO4. Mole weight: 321.42. | |
| 6-Iodonordihydrocapsaicin | 6-Iodonordihydrocapsaicin is a potent and competitive vanilloid TRPV1 (VR1) receptor antagonist with IC50 value of 10 nM. It inhibits capsaicin-induced [Ca2+]i increase in rat DRG neurons. It also inhibits guinea pig bladder and trachea contractions in vitro. It may induce luciferase gene expression. Synonyms: N-[(4-Hydroxy-2-iodo-5-methoxyphenyl)methyl]nonanamide; 6-I-CPS. Grade: ≥99% by HPLC. CAS No. 859171-97-4. Molecular formula: C17H26INO3. Mole weight: 419.30. | |
| cis-Capsaicin | cis-Capsaicin. Group: Biochemicals. Alternative Names: (6Z)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; (Z)-8-Methyl-N-vanillyl-6-nonenamide; (Z)-8-Methyl-N-vanillyl-6-nonenamide. Grades: Highly Purified. CAS No. 25775-90-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H27NO3. US Biological Life Sciences. | Worldwide |
| cis-Capsaicin | Zucapsaicin, also referred to cis-Capsaicin, is a prototype vanilloid receptor agonist used to treat osteoarthritis of the knee and other neuropathic pain. Uses: Capsaicin analogue (c175680). it is used as a tool in neurobiological research. prototype vanilloid receptor agonist. topical analgesic. Synonyms: (Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide; BRN 4261852; cis-Capsaicin; Civamide; Zucapsaicin, trade name Civanex. Grade: 98%. CAS No. 25775-90-0. Molecular formula: C18H27NO3. Mole weight: 305.42. | |
| Dihydrocapsaicin | Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF , Bax , and Caspase-3 expressions, and increased Bcl-2 , Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 19408-84-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0361. | |
| Dihydrocapsaicin | Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(4-Hydroxy-3-methoxybenzyl). Product Category: Inhibitors. Appearance: White powder. CAS No. 19408-84-5. Molecular formula: C18H29NO3. Mole weight: 307.43. Purity: 0.98. IUPACName: N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnonanamide. Canonical SMILES: CC(C)CCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC. Density: 1.026±0.06 g/ml. Product ID: ACM19408845-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Dihydro Capsaicin | Capsaicin analog. A VR1 vaniloid receptor agonist. Group: Biochemicals. Alternative Names: N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnonanamide; 8-Methyl-N-vanillylnonanamide; 6,7-Dihydrocapsaicin; Dihydrocapsaicin. Grades: Highly Purified. CAS No. 19408-84-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Dihydro Capsaicin | Dihydro Capsaicin is a terpene alkaloid found in Capsicum. Uses: Sterilization. Synonyms: Dihydrocapsaicin; 6,7-Dihydrocapsaicin; N-(4-hydroxy-3-methoxybenzyl)-8-methylnonanamide; 8-Methyl-N-vanillylnonanamide. Grade: >98%. CAS No. 19408-84-5. Molecular formula: C18H29NO3. Mole weight: 307.43. | |
| Dihydro Capsaicin-[d3] | Dihydro Capsaicin-[d3] is the labelled analogue of Dihydro Capsaicin, which is an analog of Capsaicin, a VR1 vaniloid receptor agonist. Synonyms: Dihydro Capsaicin D3; N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnonanamide-d3; 8-Methyl-N-vanillylnonanamide-d3; 6,7-Dihydrocapsaicin-d3; Dihydrocapsaicin-d3. Grade: ≥98% by HPLC; ≥99% atom D. CAS No. 1330261-21-6. Molecular formula: C18H26D3NO3. Mole weight: 310.45. | |
| Nordihydrocapsaicin | Nordihydrocapsaicin, an analog of Capsaicin (HY-10448), is an orally active compound with pungent properties and anti-cancer activities, which is found in fresh and processed peppers. Nordihydrocapsaicin can cause a burning sensation when consumed [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 28789-35-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0449. | |
| trans-Capsaicin | trans-Capsaicin. Group: Biochemicals. Alternative Names: (6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; (E)-8-Methyl-N-vanillyl-6-nonenamide; Capsaicin. Grades: Highly Purified. CAS No. 404-86-4. Pack Sizes: 1g, 5g, 10g, 25g, 50g. Molecular Formula: C18H27NO3. US Biological Life Sciences. | Worldwide |
| trans-Capsaicin-[d3] | A labelled Capsaicin analogue. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic. Synonyms: (6E)-N-[(4-hydroxy-3-(methoxy-d3)phenyl)methyl]-8-methyl-6-nonenamide; (E)-8-Methyl-N-vanillyl-6-nonenamide-d3; Capsaicin-d3; (E)-N-(4-Hydroxy-3-(methoxy-d3)benzyl)-8-methylnon-6-enamide; ALGRX 4975-d3; Adlea-d3; Axsain-d3; Capsaicine-d3; Capsin P 50-d3. Grade: > 95%. CAS No. 1217899-52-9. Molecular formula: C18H27D3NO3. Mole weight: 308.44. | |
| 1-Monoelaidin | 1-Monoelaidin is an activator of transient receptor potential vanilloid subtype 1 (TRPV1) which is known as capsaicin (CAP) receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 2716-53-2. Pack Sizes: 1g, 2.5g. Molecular Formula: C21H40O4, Molecular Weight: 356.54. US Biological Life Sciences. | Worldwide |
| 1-Monoelaidin-d5 | 1-Monoelaidin-d5 is labelled 1-Monoelaidin (M542000) which is an activator of transient receptor potential vanilloid subtype 1 (TRPV1) which is known as capsaicin (CAP) receptor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C21H35D5O4, Molecular Weight: 361.57. US Biological Life Sciences. | Worldwide |
| 2-Amino-1-(4-chlorophenyl)ethanol | 2-Amino-1-(4-chlorophenyl)ethanol is a useful synthetic intermediate in the synthesis of capsaicin analogs which exhibit potential analgesic activity. 2-Amino-1-(4-chlorophenyl)ethanol is also used as a reagent in the synthesis of imidazolyl arylamides as inhibitors of CYP24A1. Group: Biochemicals. Grades: Highly Purified. CAS No. 41870-82-0. Pack Sizes: 25mg, 250mg. Molecular Formula: C8H10ClNO, Molecular Weight: 171.62. US Biological Life Sciences. | Worldwide |
| 4-Hydroxy-3-methoxybenzaldehyde O-Methyloxime. | Capsaicin. Group: Biochemicals. Grades: Highly Purified. CAS No. 93249-67-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 4-Hydroxy-3-methoxy-d3-benzaldehyde O-Methyloxime. | Labeled Capsaicin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 5'-Iodoresiniferatoxin | 5'-Iodoresiniferatoxin is a very potent and strong competitive antagonist of the transient receptor potential vanilloid 1 (TRPV1) receptor. It is derived from resiniferatoxin (RTX), which is produced by the Moroccan succulent Euphorbia resinifera. It is iodinated at the 5-position and can be prepared from RTX by electrophilic aromatic substitution. It binds to TRPV1 (VR1) receptors expressed in HEK293 cells with Kd value of 4.3 nM and Ki value of 5.8 nM. It binds to the VR1 receptor with high affinity but does not induce RTX- or capsaicin-like effects in Xenopus laevis oocytes expressing VR1. It is 40-fold more potent than capsazepine. Synonyms: 5-I-RTX; 5'-IRTX; 6,7-Deepoxy-6,7-didehydro-5-deoxy-21-dephenyl-21-(phenylmethyl)-daphnetoxin,20-(4-hydroxy-5-iodo-3-methoxybenzeneacetate). Grade: ≥98% by HPLC. CAS No. 535974-91-5. Molecular formula: C37H39IO9. Mole weight: 754.60. | |
| (6E)-8-Methyl-6-nonenoic Acid | A compund from thermal decomposition of Capsaicin, as a possible carcinogen. Group: Biochemicals. Alternative Names: (E)-8-Methyl-. Grades: Highly Purified. CAS No. 59320-77-3. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| (6E)-8-Methyl-6-nonenoic Acid Ethyl Ester-d5 | (6E)-8-Methyl-6-nonenoic Acid Ethyl Ester-d5 is the isotope labelled analog of (6E)-8-Methyl-6-nonenoic Acid Ethyl Ester (M328235); the ethyl ester derivative of (6E)-8-Methyl-6-nonenoic Acid (M325790) which is a compound used in the synthesis of Capsaicin analogs useful for their anti-tumor activity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C12H17D5O2, Molecular Weight: 203.33. US Biological Life Sciences. | Worldwide |
| (6Z)-8-Methyl-6-nonenoic Acid (up to 10% trans isomer) | Used in the synthesis of Capsaicin analogues, useful for their anti-tumor activity. Group: Biochemicals. Alternative Names: (Z)-8-Methyl-6-Nonenoic Acid; (Z)-8-Methyl-6-nonenoic Acid; 8-Methyl-cis-6-nonenoic Acid; cis-8-Methyl-6-nonenoic Acid. Grades: Highly Purified. CAS No. 31467-60-4. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| A 784168 | A 784168 is a potent and selective TRPV1 antagonist (IC50 = 25 nM for inhibition of TRPV1 activation by 50 nM capsaicin) exhibiting no activity against a range of receptors such as TRPA1, GABA, opioid, and purinergic receptors. Synonyms: A 784168; A784168; A-784168; 3,6-Dihydro-3'-(trifluoromethyl)-N-[4-[(trifluoromethyl)sulfonyl]phenyl]-[1(2H),2'-bipyridine]-4-carboxamide; 1-[3-(trifluoromethyl)pyridin-2-yl]-N-[4-(trifluoromethylsulfonyl)phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide. Grade: ≥99% by HPLC. CAS No. 824982-41-4. Molecular formula: C19H15F6N3O3S. Mole weight: 479.4. | |
| A-784168 | A-784168 is a potent and orally active inhibitor of vanilloid receptor type 1 ( TRPV1 ). Vanilloid receptor type 1 (TRPV1) is a ligand-gated nonselective cation channel that is considered to be an important integrator of various pain stimuli such as endogenous lipids, capsaicin, heat, and low pH. A-784168 has good CNS penetration [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 824982-41-4. Pack Sizes: 5 mg. Product ID: HY-108460. | |
| AM-0466 | AM-0466 is a potent and selective Nav1.7 inhibitor (IC50 = 0.020 nM). It exhibited an effective activity in a NaV1.7-dependent model of histamine-induced pruritus (itch) and also in a capsaicin-induced nociception model of pain. Synonyms: AM 0466; AM0466. CAS No. 1642113-59-4. Molecular formula: C27H19F3N4O4S. Mole weight: 552.52. | |
| AMG-517 | AMG-517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM. Synonyms: AMG-517; AMG 517; AMG517; BD-0082; BD 0082; BD0082; BAY E 9736. Grade: >98%. CAS No. 659730-32-2. Molecular formula: C20H13F3N4O2S. Mole weight: 430.4. | |
| AMG-9810 | AMG-9810 is potent, non-vanilloid and selective TRPV1 receptor antagonist with IC50 value of 17 nM. It inhibits capsaicin-, proton-, heat- and endogenous ligand-induced activation of human and rat recombinant TRPV1 receptors. It displays antihyperalgesic properties in a rat model of inflammatory pain. It was developed by Amgen. Uses: Amg-9810 displays antihyperalgesic properties. Synonyms: AMG-9810; AMG9810; AMG 9810. (2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propanamide; 2-PropenaMide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-diMethylethyl)phenyl]-, (2E)-; (E)-3-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-enami. Grade: 98%. CAS No. 545395-94-6. Molecular formula: C21H23NO3. Mole weight: 337.41. | |
| AP18 | AP18 is a selective Transient receptor potential A1(TRPA1) channel blocker which reversibly inhibits TRPA1 with IC50 values of 3.1 and 4.5 μM at human and mouse respectively. It has been used to study TRPA1 signaling in mice and rats as well as in vitro. It blocks the transient receptor potential ankyrin 1 receptors and can reduce chronic pain associated with arthritis. It also blocks cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. It reverses CFA-induced mechanical hyperalgesia in mice. Uses: Ap18 blocks the transient receptor potential ankyrin 1 receptors and can reduce chronic pain associated with arthritis. Synonyms: AP-18; AP 18; AP18. 4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime; AP-18; 4-(4-Chlorophenyl)-3-methyl-3-buten-2-oneoxime; (NE)-N-[(Z)-4-(4-chlorophenyl)-3-methylbut-3-en-2-ylidene]hydroxylamine; (2E,3E)-4-(4-chlorophenyl)-3-methylbut-3-en-2-one oxime. Grade: 98%. CAS No. 55224-94-7. Molecular formula: C11H12ClNO. Mole weight: 209.67. | |
| Arvanil | Arvanil is a vanilloid TRPV1 (VR1) and cannabinoid CB1 agonist with Ki values of 0.3 and 0.5 μM respectively. It increases lung tidal volume, diaphragm activity, mean arterial blood pressure and inhibits lymphocyte proliferation. It also inhibits the anandamide transporter. It has analgesic, vasodilatory and anti-inflammatory effects in vivo. It is a structural analog of capsaicin. It induces analgesia in rat and mouse models of pain. It is resistant to hydrolysis by FAAH. It is a potent inhibitor of anandamide accumulation. It inhibits growth of astrocytoma xenograft tumors in mice. It mimics the effect of neural precursor cells and has been shown to kill TRPV1-expressing tumor cells by secreting endovanilloids. Synonyms: RT-011322; B-6699; I14-44667; RT011322; B6699; I1444667; N-[(4-Hydroxy-3-methoxyphenyl)methyl]-5Z,8Z,11Z,14Z-eicosatetraenamide; (5Z,8Z,11Z,14Z)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-5,8,11,14-Eicosatetraenamide; N-Vanillylarachidonamide; (all-Z)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-5,8,11,14-eicosatetraenamide. Grade: ≥98% by HPLC. CAS No. 128007-31-8. Molecular formula: C28H41NO3. Mole weight: 439.64. | |
| AT-121 | T-121 is a dual μ-opioid and nociceptin receptor partial agonist (Kis = 16.49 and 3.67 nM, respectively). AT-121 can decrease capsaicin-induced thermal allodynia without increasing scratching activity in rhesus monkeys in a dose-dependent manner. Synonyms: AT-121; 2099681-31-7; N-[2-[1,2-dihydro-1'-[cis-4-(1-methylethyl)cyclohexyl]-3-oxospiro[isoquinoline-4(3H),4'-piperidin]-2-yl]ethyl]-sulfamide; 3-oxo-1'-(4-propan-2-ylcyclohexyl)-2-[2-(sulfamoylamino)ethyl]spiro[1H-isoquinoline-4,4'-piperidine]; SCHEMBL18920959; SCHEMBL20230173; SCHEMBL21179793; DTXSID801336428; GLXC-25688; EX-A8003; AKOS040755934; HY-112692; CS-0062666; Q56448036; N-{2-[1'-(cis-4-Isopropylcyclohexyl)-3-oxo-1H-spiro[isoquinoline-4,4'-piperidin]-2(3H)-yl]ethyl}sulfuric diamide. Grade: ≥95%. CAS No. 2099681-31-7. Molecular formula: C24H38N4O3S. Mole weight: 462.65. | |
| AY-NH2 | AY-NH is a selective proteinase-activated receptor 4 (PAR4) receptor agonist peptide. It stimulates aggregation of rat and human platelets in vitro. It reduces expression of glycoprotein (GP) Ib, and increases expression of GPIIb/IIIa on the surface of human platelets. It induces relaxation of isolated rat aortic rings and contraction of rat gastric longitudinal muscle strips. It also inhibits calcium mobilization evoked by capsaicin in rat sensory neurons. It increases paw thickness in a rat paw edema inflammation model in vivo. Synonyms: PAR-4 Agonist Peptide, amide; L-Alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide; PAR-4-AP; Proteinase-activated Receptor 4 Activating Peptide. Grade: 98%. CAS No. 352017-71-1. Molecular formula: C34H48N8O7. Mole weight: 680.79. | |
| BCTC | BCTC is a TRPA1 and TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 with IC50 values of 35 and 6 nM, respectively. Uses: Orally effective vanilloid receptor 1. Synonyms: 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)piperazine-1-carboxamide. Grade: ≥98%. CAS No. 393514-24-4. Molecular formula: C20H25ClN4O. Mole weight: 372.89. | |
| Capsazepine - CAS 138977-28-3 | A competitive antagonist of Capsaicin and resiniferatoxin. Capsazepine (1 μM) blocks capsaicin (60 nM) stimulated firing of C-fibers. Group: Fluorescence/luminescence spectroscopy. | |
| Capsiate | Capsiate, as a capsaicin analogue extracted from a non-pungent cultivar of CH-19 sweet red pepper, is an orally active agonist of TRPV1 [1]. Uses: Scientific research. Group: Natural products. CAS No. 205687-01-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8377. | |
| Capsiconiate | Capsiconiate is a coniferyl ester that has been isolated from certain plants in the Solanaceae family, including plants in the genus Capsicum. It is a TRPV1 agonist, non-selective cation and calcium permeable channel. Like capsaicin, capsiconiate is an agonist of the transient receptor potential vanilloid receptor TRPV1 (EC50 = 3.2 μM). But the maximum response induced by capsiconiate through TRPV1 is only 20% of that of capsaicin. Synonyms: Coniferyl (E)-8-methyl-6-nonenoate. Grade: ≥98%. CAS No. 946572-73-2. Molecular formula: C20H28O4. Mole weight: 332.4. | |
| Capsicum Extract | Capsicum Extract. Applications: Capsicum extract(capsaicin) is widely used in medicine, military and chemical industry. natural capsaicin production are mainly used in the reseach and development of medicine, by its powerful effect of relieve pain. Group: Others. Purity: Capsaicin 95%. Source: Chili Pepper, dicotyledonous plants, one year or perennial herbaceous plants, native to tropical South America, the late Ming dynasty was introduced into China. There are spicy, for food. Chili grown in mild climate , like water. Chili contain rich vitamin C, beta-carotene, folic acid, magnesium and potassium; Capsaicin in capsicum also has anti-inflammatory and antioxidant effect. Vitamin C content in chili ranks first in the vegetables. Capsicum Extract; Capsicum annuum Linn. Cat No: EXTC-177. |  |
| CAY10448 | Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel. It is also an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of 10 nM. Synonyms: CAY 10448; CAY-10448. Grade: ≥98%. CAS No. 1177195-52-6. Molecular formula: C18H28INO3. Mole weight: 433.3. | |
| (E)-8-Methyl-6-nonenoic acid | (E)-8-Methyl-6-nonenoic acid is a thermal degradant of Capsaicin. Synonyms: 8-methylnonenoate; 8-Methyl-6-nonenoic acid; (E)-8-methylnon-6-enoic acid. Grade: >95%. CAS No. 59320-77-3. Molecular formula: C10H18O2. Mole weight: 170.25. | |
| EMA401 | EMA401 is an orally bioavailable, potent and highly selective antagonist of the angiotensin II type 2 receptor (AT2; IC50s = 39.5 and 408,000 nM for rat recombinant AT2 and AT1, respectively). It inhibits capsaicin-induced calcium influx in cultured human dorsal root ganglion (hDRG) neurons (IC50 = 10 nM) and reduces neurite density and length in rat DRG neuronal cultures. Synonyms: EMA 401; EMA-401; Olodanrigan; (3S)-2-(2,2-diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinolinecarboxylic acid. Grade: ≥ 95 %. CAS No. 1316755-16-4. Molecular formula: C32H29NO5. Mole weight: 507.6. | |
| EST64454 HCl | EST64454 is a Highly Soluble σ1 Receptor Antagonist Clinical Candidate for Pain Management. EST64454 shows an outstanding aqueous solubility, which together with its high permeability in Caco-2 cells will allow its classification as a BCS class I compound. It also shows high metabolic stability in all species, linked to an adequate pharmacokinetic profile in rodents, and antinociceptive properties in the capsaicin and partial sciatic nerve ligation models in mice. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EST64454 HCl; EST64454 hydrochloride; EST64454; EST-64454; EST 64454. Product Category: Antagonists. Appearance: Solid powder. CAS No. 1950569-11-5. Molecular formula: C18H23ClF2N4O2. Mole weight: 400.85. Purity: >98%. IUPACName: 1-(4-(2-((1-(3,4-difluorophenyl)-1H-pyrazol-3-yl)methoxy)ethyl)piperazin-1-yl)ethan-1-one hydrochloride. Canonical SMILES: CC(N1CCN(CCOCC2=NN(C3=CC=C(F)C(F)=C3)C=C2)CC1)=O.[H]Cl. Product ID: ACM1950569115. Alfa Chemistry ISO 9001:2015 Certified. | |
| Mavatrep | Mavatrep (JNJ-39439335) is an orally active, selective and potent TRPV1 antagonist with high affinity for hTRPV1 channels (Ki=6.5 nM). Mavatrep antagonizes capsaicin-induced Ca2+ influx with an IC50 value of 4.6 nM. Mavatrep can be used in some studies of neuropathic pain[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-39439335. CAS No. 956274-94-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16935. | |
| Nonivamide | Nonivamide. Alternative Names: N-((Hydroxy-3-methoxyphenyl)methyl)4-nonanamide;N-Nonanoyl vanillylamide;Nonanamide, N-((4-hydroxy-3-methoxyphenyl)meth;SYNTHETIC CAPSAICIN;PELARGONYL VANILLYLAMIDE;PELARGONIC ACID VANILLYLAMIDE;N-PELARGONIC ACID VANILLYLAMIDE. CAS No. 2444-46-4. Product ID: PIPE-0304. Molecular formula: C17H27NO3. Mole weight: 293.4. EINECS: 219-484-1. SMILES: CCCCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC. Appearance: Powder. Category: Natural Extract. |  |
| Nonivamide | Nonivamide. Group: Biochemicals. Alternative Names: Capsaicin. Grades: Highly Purified. CAS No. 2444-46-4,618-92-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C17H27NO3. US Biological Life Sciences. | Worldwide |
| N-Vanillyldecanamide | N-Vanillyldecanamide, a capsaicinoid isolated from the fruits of Capsicum annuum , significantly reduced the radical length of Lactuca sativa seedling in a dose-dependent manner [1]. Uses: Scientific research. Group: Natural products. CAS No. 31078-36-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N5099. | |
| TRPV4 Antagonist I, RN-1734 (2, 4-Dichloro-N-isopropyl-N- (2-isopropylaminoethyl) benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734) | A cell-permeable benzenesulfonamide compound that selectively antagonizes TRPV4 agonist 4a-PDD-stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9uM, respectively, in HEK293 expressing human, rat, or mouse TRPV4) without affecting the activity of three other human TRP (transient receptor potential) channels, including capsaicin- activated TRPV1, camphor-activated TRPV3, and methanol-activated TRPM8 (IC50 >30uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 946387-07-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Vanillylamine | Vanillylamine is a derivative of vanillin is synthesized through a transaminase reaction in the phenylpropanoid pathway of capsaicinoid synthesis [1]. Uses: Scientific research. Group: Natural products. CAS No. 1196-92-5. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W097899. | |
| Vanillylamine-d3 Hydrochloride | A labeled metabolite of Capsaicin. Group: Biochemicals. Alternative Names: 4-(Aminomethyl)-2-methoxyphenol-d3 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Vanillylamine Hydrochloride | A metabolite of Capsaicin. Group: Biochemicals. Alternative Names: 4-(Aminomethyl)-2-methoxyphenol Hydrochloride. Grades: Highly Purified. CAS No. 7149-10-2. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| Voacangine | Voacangine is an antagonist for TRPV1 and TRPM8 but as an agonist for TRPA1 ( EC 50 =8 μM). Voacangine competitively blockes capsaicin binding to TRPV1 ( IC 50 =50 μM). Voacangine competitively inhibits the binding of menthol to TRPM8 ( IC 50 =9 μM) and it shows noncompetitive inhibition against icilin ( IC 50 =7 μM). Voacangine selectively abrogates chemical agonist-induced TRPM8 activation and did not affect cold-induced activation. Voacangine is an alkaloid isolated from the root bark of Voacanga africana [1]. Uses: Scientific research. Group: Natural products. CAS No. 510-22-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7536. | |
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