Capsaicin Suppliers USA
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Product | Description | |
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Capsaicin Quick inquiry Where to buy Suppliers range | 1g Pack Size. Group: Aroma Chemicals, Diagnostic Raw Materials, Research Organics & Inorganics, Testing Standards. Formula: C18H27NO3. CAS No. 404-86-4. Prepack ID 31397045-1g. Molecular Weight 305.41. See USA prepack pricing. | |
Capsaicin Quick inquiry Where to buy Suppliers range | It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic. Group: Biochemicals. Alternative Names: (6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; trans-8-Methyl-N-vanillyl-6-nonenamide; Axsain; Mioton; Zacin; Zostrix. Grades: Highly Purified. CAS No. 404-86-4. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
Capsaicin Quick inquiry Where to buy Suppliers range | Capsaicin - Product ID: NST-10-110. Category: Alkaloids. Alternative Names: Adlea, Ausanil, Axsain, Capsaicine, Capsicin, Dolenon, Mioton, Ovocap, Qutenza, Zostrix. Purity: 98%. Test method: HPLC. CAS No. 404-86-4. Pack Sizes: 1g, 2g, 5g, 10g. Appearance: Off-white to yellowish Powder. Molecular formula: C18H27NO3. Mole weight: 305.41. Storage: +2 +8 °C. | |
Capsaicin Quick inquiry Where to buy Suppliers range | Capsaicin. Group: Biobased Products. Alternative Names: (E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide. Grades: 98%. CAS No. 404-86-4. Product ID: BBC404864. Molecular formula: C18H27NO3. Mole weight: 305.41. IUPAC Name: (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide. Appearance: White powder. Density: 1.1 g/ml. SMILES: CC (C)/C=C/CCCCC (=O)NCC1=CC (=C (C=C1)O)OC. | |
Capsaicin, (6E)- Quick inquiry Where to buy Suppliers range | Capsaicin, (6E)-. Group: Biochemicals. CAS No. 404-86-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Capsaicin 99+% (GC) Quick inquiry Where to buy Suppliers range | Capsaicin 99+% (GC). Group: Biochemicals. Grades: GC. CAS No. 404-86-4. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
Capsaicin-d3 Quick inquiry Where to buy Suppliers range | Capsaicin-d3. Group: Biochemicals. Alternative Names: (6E)-N-[(4-Hydroxy-3-methoxy-d3-phenyl)methyl]-8-methyl-6-nonenamide; trans-8-Methyl-N-vanillyl-6-nonenamide-d3; Axsain-d3; Mioton-d3; Zacin-d3; Zostrix-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Capsaicin ≥97% (Single peak, HPLC) Quick inquiry Where to buy Suppliers range | Capsaicin ≥97% (Single peak, HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 404-86-4. Pack Sizes: 100mg, 250mg, 25mg, 1g. US Biological Life Sciences. | Worldwide |
16,17-Dehydro capsaicin Quick inquiry Where to buy Suppliers range | 16,17-Dehydro capsaicin. Group: Biochemicals. Alternative Names: (6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6,8-nonadienamide. Grades: Highly Purified. CAS No. 509101-57-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H25NO3. US Biological Life Sciences. | Worldwide |
16,17-Dehydro Capsaicin Quick inquiry Where to buy Suppliers range | A dehydrogenated metabolite of Capsaicin. Synonyms: (6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6,8-nonadienamide. Grades: > 95%. CAS No. 509101-57-9. Molecular formula: C18H25NO3. Mole weight: 303.4. | |
16-Hydroxy Capsaicin Quick inquiry Where to buy Suppliers range | A metabolite of Capsaicin. Group: Biochemicals. Alternative Names: (6E)-8-Hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide. Grades: Highly Purified. CAS No. 112848-19-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C??H??NO?, Molecular Weight: 321.41. US Biological Life Sciences. | Worldwide |
16-Hydroxy Capsaicin Quick inquiry Where to buy Suppliers range | A metabolite of Capsaicin. Synonyms: (6E)-8-Hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide. Grades: > 95%. CAS No. 112848-19-8. Molecular formula: C18H27NO4. Mole weight: 321.42. | |
17-Hydroxy capsaicin Quick inquiry Where to buy Suppliers range | 17-Hydroxy capsaicin. Group: Biochemicals. Alternative Names: (6E)-9-Hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; ω-Hydroxycapsaicin. Grades: Highly Purified. CAS No. 69173-71-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H27NO4. US Biological Life Sciences. | Worldwide |
17-Hydroxy Capsaicin Quick inquiry Where to buy Suppliers range | A metabolite of Capsaicin. Synonyms: (6E)-9-Hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; ω-Hydroxycapsaicin. Grades: > 95%. CAS No. 69173-71-3. Molecular formula: C18H27NO4. Mole weight: 321.42. | |
826-Capsaicin and heat units in chilli powder/sauce (FC298 Chilli powder; FC304 Chilli sauce) Quick inquiry Where to buy Suppliers range | 826-Capsaicin and heat units in chilli powder/sauce (FC298 Chilli powder; FC304 Chilli sauce). Uses: For analytical and research use. Group: Food & Beverage Proficiency Testing. Catalog: APS005166. Format: 20g of dried chilli powder. | |
cis-Capsaicin Quick inquiry Where to buy Suppliers range | Zucapsaicin, also referred to cis-Capsaicin, is a prototype vanilloid receptor agonist used to treat osteoarthritis of the knee and other neuropathic pain. Uses: Capsaicin analogue (c175680). it is used as a tool in neurobiological research. prototype vanilloid receptor agonist. topical analgesic. Synonyms: (Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide; BRN 4261852; cis-Capsaicin; Civamide; Zucapsaicin, trade name Civanex. Grades: 98%. CAS No. 25775-90-0. Molecular formula: C18H27NO3. Mole weight: 305.42. | |
cis-Capsaicin Quick inquiry Where to buy Suppliers range | cis-Capsaicin. Group: Biochemicals. Alternative Names: (6Z)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; (Z)-8-Methyl-N-vanillyl-6-nonenamide; (Z)-8-Methyl-N-vanillyl-6-nonenamide. Grades: Highly Purified. CAS No. 25775-90-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H27NO3. US Biological Life Sciences. | Worldwide |
Dihydro Capsaicin Quick inquiry Where to buy Suppliers range | Capsaicin analog. A VR1 vaniloid receptor agonist. Group: Biochemicals. Alternative Names: N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnonanamide; 8-Methyl-N-vanillylnonanamide; 6,7-Dihydrocapsaicin; Dihydrocapsaicin. Grades: Highly Purified. CAS No. 19408-84-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Dihydro Capsaicin Quick inquiry Where to buy Suppliers range | Dihydro Capsaicin is a terpene alkaloid found in Capsicum. Uses: Sterilization. Synonyms: Dihydrocapsaicin; 6,7-Dihydrocapsaicin; N-(4-hydroxy-3-methoxybenzyl)-8-methylnonanamide; 8-Methyl-N-vanillylnonanamide. Grades: >98%. CAS No. 19408-84-5. Molecular formula: C18H29NO3. Mole weight: 307.43. | |
Nordihydro Capsaicin Quick inquiry Where to buy Suppliers range | Nordihydrocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers (Capsicum). It accounts for about 7% of the total capsaicinoids mixture and has about half the pungency of capsaicin. Pure nordihydrocapsaicin is a lipophilic colorless odorless crystalline to waxy compound. Synonyms: N-[(4-Hydroxy-3-methoxyphenyl)methyl]-7-methyl-octanamide; Norhydrocapsaicin; Octanamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-7-methyl-. Grades: >98%. CAS No. 28789-35-7. Molecular formula: C17H27NO3. Mole weight: 293.41. | |
trans-Capsaicin Quick inquiry Where to buy Suppliers range | trans-Capsaicin. Group: Biochemicals. Alternative Names: (6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; (E)-8-Methyl-N-vanillyl-6-nonenamide; Capsaicin. Grades: Highly Purified. CAS No. 404-86-4. Pack Sizes: 1g, 5g, 10g, 25g, 50g. Molecular Formula: C18H27NO3. US Biological Life Sciences. | Worldwide |
1-Monoelaidin Quick inquiry Where to buy Suppliers range | 1-Monoelaidin is an activator of transient receptor potential vanilloid subtype 1 (TRPV1) which is known as capsaicin (CAP) receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 2716-53-2. Pack Sizes: 1g, 2.5g. Molecular Formula: C21H40O4, Molecular Weight: 356.54. US Biological Life Sciences. | Worldwide |
1-Monoelaidin-d5 Quick inquiry Where to buy Suppliers range | 1-Monoelaidin-d5 is labelled 1-Monoelaidin (M542000) which is an activator of transient receptor potential vanilloid subtype 1 (TRPV1) which is known as capsaicin (CAP) receptor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C21H35D5O4, Molecular Weight: 361.57. US Biological Life Sciences. | Worldwide |
2-Amino-1-(4-chlorophenyl)ethanol Quick inquiry Where to buy Suppliers range | 2-Amino-1-(4-chlorophenyl)ethanol is a useful synthetic intermediate in the synthesis of capsaicin analogs which exhibit potential analgesic activity. 2-Amino-1-(4-chlorophenyl)ethanol is also used as a reagent in the synthesis of imidazolyl arylamides as inhibitors of CYP24A1. Group: Biochemicals. Grades: Highly Purified. CAS No. 41870-82-0. Pack Sizes: 25mg, 250mg. Molecular Formula: C8H10ClNO, Molecular Weight: 171.62. US Biological Life Sciences. | Worldwide |
4-Hydroxy-3-methoxybenzaldehyde O-Methyloxime. Quick inquiry Where to buy Suppliers range | Capsaicin. Group: Biochemicals. Grades: Highly Purified. CAS No. 93249-67-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
4-Hydroxy-3-methoxy-d3-benzaldehyde O-Methyloxime. Quick inquiry Where to buy Suppliers range | Labeled Capsaicin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
5'-Iodoresiniferatoxin Quick inquiry Where to buy Suppliers range | 5'-Iodoresiniferatoxin is a very potent and strong competitive antagonist of the transient receptor potential vanilloid 1 (TRPV1) receptor. It is derived from resiniferatoxin (RTX), which is produced by the Moroccan succulent Euphorbia resinifera. It is iodinated at the 5-position and can be prepared from RTX by electrophilic aromatic substitution. It binds to TRPV1 (VR1) receptors expressed in HEK293 cells with Kd value of 4.3 nM and Ki value of 5.8 nM. It binds to the VR1 receptor with high affinity but does not induce RTX- or capsaicin-like effects in Xenopus laevis oocytes expressing VR1. It is 40-fold more potent than capsazepine. Synonyms: 5-I-RTX; 5'-IRTX; 6,7-Deepoxy-6,7-didehydro-5-deoxy-21-dephenyl-21-(phenylmethyl)-daphnetoxin,20-(4-hydroxy-5-iodo-3-methoxybenzeneacetate). Grades: ≥98% by HPLC. CAS No. 535974-91-5. Molecular formula: C37H39IO9. Mole weight: 754.60. | |
(6E)-8-Methyl-6-nonenoic Acid Quick inquiry Where to buy Suppliers range | A compund from thermal decomposition of Capsaicin, as a possible carcinogen. Group: Biochemicals. Alternative Names: (E)-8-Methyl-. Grades: Highly Purified. CAS No. 59320-77-3. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
(6E)-8-Methyl-6-nonenoic Acid Ethyl Ester-d5 Quick inquiry Where to buy Suppliers range | (6E)-8-Methyl-6-nonenoic Acid Ethyl Ester-d5 is the isotope labelled analog of (6E)-8-Methyl-6-nonenoic Acid Ethyl Ester (M328235); the ethyl ester derivative of (6E)-8-Methyl-6-nonenoic Acid (M325790) which is a compound used in the synthesis of Capsaicin analogs useful for their anti-tumor activity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C12H17D5O2, Molecular Weight: 203.33. US Biological Life Sciences. | Worldwide |
6-Iodonordihydrocapsaicin Quick inquiry Where to buy Suppliers range | 6-Iodonordihydrocapsaicin is a potent and competitive vanilloid TRPV1 (VR1) receptor antagonist with IC50 value of 10 nM. It inhibits capsaicin-induced [Ca2+]i increase in rat DRG neurons. It also inhibits guinea pig bladder and trachea contractions in vitro. It may induce luciferase gene expression. Synonyms: N-[(4-Hydroxy-2-iodo-5-methoxyphenyl)methyl]nonanamide; 6-I-CPS. Grades: ≥99% by HPLC. CAS No. 859171-97-4. Molecular formula: C17H26INO3. Mole weight: 419.30. | |
(6Z)-8-Methyl-6-nonenoic Acid (up to 10% trans isomer) Quick inquiry Where to buy Suppliers range | Used in the synthesis of Capsaicin analogues, useful for their anti-tumor activity. Group: Biochemicals. Alternative Names: (Z)-8-Methyl-6-Nonenoic Acid; (Z)-8-Methyl-6-nonenoic Acid; 8-Methyl-cis-6-nonenoic Acid; cis-8-Methyl-6-nonenoic Acid. Grades: Highly Purified. CAS No. 31467-60-4. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
A 784168 Quick inquiry Where to buy Suppliers range | A 784168 is a potent and selective TRPV1 antagonist (IC50 = 25 nM for inhibition of TRPV1 activation by 50 nM capsaicin) exhibiting no activity against a range of receptors such as TRPA1, GABA, opioid, and purinergic receptors. Synonyms: A 784168; A784168; A-784168; 3,6-Dihydro-3'-(trifluoromethyl)-N-[4-[(trifluoromethyl)sulfonyl]phenyl]-[1(2H),2'-bipyridine]-4-carboxamide; 1-[3-(trifluoromethyl)pyridin-2-yl]-N-[4-(trifluoromethylsulfonyl)phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide. Grades: ≥99% by HPLC. CAS No. 824982-41-4. Molecular formula: C19H15F6N3O3S. Mole weight: 479.4. | |
AM-0466 Quick inquiry Where to buy Suppliers range | AM-0466 is a potent and selective Nav1.7 inhibitor (IC50 = 0.020 nM). It exhibited an effective activity in a NaV1.7-dependent model of histamine-induced pruritus (itch) and also in a capsaicin-induced nociception model of pain. Synonyms: AM 0466; AM0466. CAS No. 1642113-59-4. Molecular formula: C27H19F3N4O4S. Mole weight: 552.52. | |
AMG-517 Quick inquiry Where to buy Suppliers range | AMG-517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM. Synonyms: AMG-517; AMG 517; AMG517; BD-0082; BD 0082; BD0082; BAY E 9736. Grades: >98%. CAS No. 659730-32-2. Molecular formula: C20H13F3N4O2S. Mole weight: 430.4. | |
AMG-9810 Quick inquiry Where to buy Suppliers range | AMG-9810 is potent, non-vanilloid and selective TRPV1 receptor antagonist with IC50 value of 17 nM. It inhibits capsaicin-, proton-, heat- and endogenous ligand-induced activation of human and rat recombinant TRPV1 receptors. It displays antihyperalgesic properties in a rat model of inflammatory pain. It was developed by Amgen. Uses: Amg-9810 displays antihyperalgesic properties. Synonyms: AMG-9810; AMG9810; AMG 9810. (2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propanamide;2-PropenaMide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-diMethylethyl)phenyl]-, (2E)-;(E)-3-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-enami. Grades: 98%. CAS No. 545395-94-6. Molecular formula: C21H23NO3. Mole weight: 337.41. | |
AP18 Quick inquiry Where to buy Suppliers range | AP18 is a selective Transient receptor potential A1(TRPA1) channel blocker which reversibly inhibits TRPA1 with IC50 values of 3.1 and 4.5 μM at human and mouse respectively. It has been used to study TRPA1 signaling in mice and rats as well as in vitro. It blocks the transient receptor potential ankyrin 1 receptors and can reduce chronic pain associated with arthritis. It also blocks cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. It reverses CFA-induced mechanical hyperalgesia in mice. Uses: Ap18 blocks the transient receptor potential ankyrin 1 receptors and can reduce chronic pain associated with arthritis. Synonyms: AP-18; AP 18; AP18. 4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime;AP-18;4-(4-Chlorophenyl)-3-methyl-3-buten-2-oneoxime;(NE)-N-[(Z)-4-(4-chlorophenyl)-3-methylbut-3-en-2-ylidene]hydroxylamine;(2E,3E)-4-(4-chlorophenyl)-3-methylbut-3-en-2-one oxime. Grades: 98%. CAS No. 55224-94-7. Molecular formula: C11H12ClNO. Mole weight: 209.67. | |
Arvanil Quick inquiry Where to buy Suppliers range | Arvanil is a vanilloid TRPV1 (VR1) and cannabinoid CB1 agonist with Ki values of 0.3 and 0.5 μM respectively. It increases lung tidal volume, diaphragm activity, mean arterial blood pressure and inhibits lymphocyte proliferation. It also inhibits the anandamide transporter. It has analgesic, vasodilatory and anti-inflammatory effects in vivo. It is a structural analog of capsaicin. It induces analgesia in rat and mouse models of pain. It is resistant to hydrolysis by FAAH. It is a potent inhibitor of anandamide accumulation. It inhibits growth of astrocytoma xenograft tumors in mice. It mimics the effect of neural precursor cells and has been shown to kill TRPV1-expressing tumor cells by secreting endovanilloids. Synonyms: RT-011322; B-6699; I14-44667; RT011322; B6699; I1444667; N-[(4-Hydroxy-3-methoxyphenyl)methyl]-5Z,8Z,11Z,14Z-eicosatetraenamide; (5Z,8Z,11Z,14Z)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-5,8,11,14-Eicosatetraenamide; N-Vanillylarachidonamide; (all-Z)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-5,8,11,14-eicosatetraenamide. Grades: ≥98% by HPLC. CAS No. 128007-31-8. Molecular formula: C28H41NO3. Mole weight: 439.64. | |
AT-121 Quick inquiry Where to buy Suppliers range | T-121 is a dual μ-opioid and nociceptin receptor partial agonist (Kis = 16.49 and 3.67 nM, respectively). AT-121 can decrease capsaicin-induced thermal allodynia without increasing scratching activity in rhesus monkeys in a dose-dependent manner. Synonyms: AT-121; 2099681-31-7; N-[2-[1,2-dihydro-1'-[cis-4-(1-methylethyl)cyclohexyl]-3-oxospiro[isoquinoline-4(3H),4'-piperidin]-2-yl]ethyl]-sulfamide; 3-oxo-1'-(4-propan-2-ylcyclohexyl)-2-[2-(sulfamoylamino)ethyl]spiro[1H-isoquinoline-4,4'-piperidine]; SCHEMBL18920959; SCHEMBL20230173; SCHEMBL21179793; DTXSID801336428; GLXC-25688; EX-A8003; AKOS040755934; HY-112692; CS-0062666; Q56448036; N-{2-[1'-(cis-4-Isopropylcyclohexyl)-3-oxo-1H-spiro[isoquinoline-4,4'-piperidin]-2(3H)-yl]ethyl}sulfuric diamide. Grades: ≥95%. CAS No. 2099681-31-7. Molecular formula: C24H38N4O3S. Mole weight: 462.65. | |
AY-NH2 Quick inquiry Where to buy Suppliers range | AY-NH is a selective proteinase-activated receptor 4 (PAR4) receptor agonist peptide. It stimulates aggregation of rat and human platelets in vitro. It reduces expression of glycoprotein (GP) Ib, and increases expression of GPIIb/IIIa on the surface of human platelets. It induces relaxation of isolated rat aortic rings and contraction of rat gastric longitudinal muscle strips. It also inhibits calcium mobilization evoked by capsaicin in rat sensory neurons. It increases paw thickness in a rat paw edema inflammation model in vivo. Synonyms: PAR-4 Agonist Peptide, amide; L-Alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide; PAR-4-AP; Proteinase-activated Receptor 4 Activating Peptide. Grades: 98%. CAS No. 352017-71-1. Molecular formula: C34H48N8O7. Mole weight: 680.79. | |
BCTC Quick inquiry Where to buy Suppliers range | BCTC is a TRPA1 and TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 with IC50 values of 35 and 6 nM, respectively. Uses: Orally effective vanilloid receptor 1. Synonyms: 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)piperazine-1-carboxamide. Grades: ≥98%. CAS No. 393514-24-4. Molecular formula: C20H25ClN4O. Mole weight: 372.89. | |
Capsiconiate Quick inquiry Where to buy Suppliers range | Capsiconiate is a coniferyl ester that has been isolated from certain plants in the Solanaceae family, including plants in the genus Capsicum. It is a TRPV1 agonist, non-selective cation and calcium permeable channel. Like capsaicin, capsiconiate is an agonist of the transient receptor potential vanilloid receptor TRPV1 (EC50 = 3.2 μM). But the maximum response induced by capsiconiate through TRPV1 is only 20% of that of capsaicin. Synonyms: Coniferyl (E)-8-methyl-6-nonenoate. Grades: ≥98%. CAS No. 946572-73-2. Molecular formula: C20H28O4. Mole weight: 332.4. | |
CAY10448 Quick inquiry Where to buy Suppliers range | Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel. It is also an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of 10 nM. Synonyms: CAY 10448; CAY-10448. Grades: ≥98%. CAS No. 1177195-52-6. Molecular formula: C18H28INO3. Mole weight: 433.3. | |
Chili Pepper Fruit Extract Quick inquiry Where to buy Suppliers range | Chili pepper fruit extract contains several components that have strong hyperaemic and rubefacient effects on the skin by increasing neuron-peptide release and directly stimulating local blood flow. Capsicum's main active components are capsaicinoids, representing between 0.1 % to 1.5 % of the dry fruit weight. The most important of these components is capsaicin (70 % of total) which chemically is the vanillylamide of an 8-methyl-(trans)-non-6-enoic acid. Uses: Massage creams, anti-cellulite products and hair treatments. Group: Skin Actives. CAS No. 7732-18-5 / 85940-30-3. Product ID: ACM7732185-225. | |
Dihydrocapsaicin Quick inquiry Where to buy Suppliers range | Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat. Group: Biobased Products. Alternative Names: N-(4-Hydroxy-3-methoxybenzyl). Grades: 98%. CAS No. 19408-84-5. Product ID: BBC19408845. Molecular formula: C18H29NO3. Mole weight: 307.43. IUPAC Name: N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnonanamide. Appearance: White powder. Density: 1.026±0.06 g/ml. SMILES: CC(C)CCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC. | |
(E)-8-Methyl-6-nonenoic acid Quick inquiry Where to buy Suppliers range | (E)-8-Methyl-6-nonenoic acid is a thermal degradant of Capsaicin. Synonyms: 8-methylnonenoate; 8-Methyl-6-nonenoic acid; (E)-8-methylnon-6-enoic acid. Grades: >95%. CAS No. 59320-77-3. Molecular formula: C10H18O2. Mole weight: 170.25. | |
EMA401 Quick inquiry Where to buy Suppliers range | EMA401 is an orally bioavailable, potent and highly selective antagonist of the angiotensin II type 2 receptor (AT2; IC50s = 39.5 and 408,000 nM for rat recombinant AT2 and AT1, respectively). It inhibits capsaicin-induced calcium influx in cultured human dorsal root ganglion (hDRG) neurons (IC50 = 10 nM) and reduces neurite density and length in rat DRG neuronal cultures. Synonyms: EMA 401; EMA-401; Olodanrigan; (3S)-2-(2,2-diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinolinecarboxylic acid. Grades: ≥ 95 %. CAS No. 1316755-16-4. Molecular formula: C32H29NO5. Mole weight: 507.6. | |
JNJ-17203212 Quick inquiry Where to buy Suppliers range | JNJ-17203212 is a novel, reversible, and selective TRPV1 antagonist which could not inhibit related TRP channels. Its IC50 values are 65 nM and 102 nM for human TRPV1 and rat TRPV1. It could reduce sensitivity to luminal distension in both an acute, noninflammatory and a chronic, post-inflammatory rodent model of colonic hypersensitivity. It inhibits capsaicin- and H+-induced channel activation, which pIC50 values are 6.32 and 7.23 respectively. It exhibits antitussive and analgesic activity in vivo. Uses: Jnj-17203212 could reduce sensitivity to luminal distension in both an acute, noninflammatory and a chronic, post-inflammatory rodent model of colonic hypersensitivity. it inhibits capsaicin- and h+-induced channel activation. it exhibits antitussive and analgesic activity in vivo. Synonyms: JNJ-17203212; JNJ 17203212; JNJ17203212. 4-[3-(Trifluoromethyl)-2-pyridinyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarboxamide;1-PiperazinecarboxaMide, 4-[3-(trifluoroMethyl)-2-pyridinyl]-N-[5-(trifluoroMethyl)-2-pyridinyl]-;N1-(3-Trifluoromethylpyrid-2-yl)-N4-(4-trifluoromethylpyrid-2-yl)carbamoylpiperazine. Grades: >99 %. CAS No. 821768-06-3. Molecular formula: C17H15F6N5O. Mole weight: 419.32. | |
JYL1421 Quick inquiry Where to buy Suppliers range | JYL1421 is a TRPV1 receptor antagonist. JYL1421 concentration-dependently (0.1-2 mM) inhibited capsaicin-evoked substance P, calcitonin gene-related peptide and somatostatin release from isolated tracheae. It also concentration-dependently decreased capsaicin-induced Ca(2+) accumulation in cultured trigeminal ganglion cells. Synonyms: 3-[ (4-Tert-butylphenyl) methyl]-1-[ (3-fluoro-4-methanesulfonamidophenyl) methyl]thiourea. Grades: ≥95%. CAS No. 401907-26-4. Molecular formula: C20H26FN3O2S2. Mole weight: 423.6. | |
Mavatrep Quick inquiry Where to buy Suppliers range | Mavatrep is an orally bioavailable, potent and selective TRPV1 antagonist with Ki value of 6.5 nM, which exhibits minimal effect on the enzymatic activity of CYP isoforms 3A4, 1A2, and 2D6. It antagonizes capsaicin-induced Ca2+ influx, with an IC50 value of 4.6 nM in a TRPV1 functional assay, using cells expressing recombinant human TRPV1 channels. It blocks the activation of hTRPV1 channels by Capsaicin and pH in a concentration-dependent fashion, with IC50 values of 23 and 6.8 nM respectively. It exhibits superior pharmacodynamic properties in the CFA model of inflammatory pain in vivo. It was selected for clinical development for the treatment of pain. It was developed by Johnson & Johnson and now in clinic phase 1 with no progress. Uses: Mavatrep was selected for clinical development for the treatment of pain. Synonyms: JNJ-39439335; JNJ 39439335; JNJ39439335; 2-[2-[2-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-3H-benzimidazol-5-yl]phenyl]propan-2-ol. Grades: >98 %. CAS No. 956274-94-5. Molecular formula: C25H21F3N2O. Mole weight: 422.44. | |
Nonivamide Quick inquiry Where to buy Suppliers range | Nonivamide. Group: Biochemicals. Alternative Names: Capsaicin. Grades: Highly Purified. CAS No. 2444-46-4,618-92-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C17H27NO3. US Biological Life Sciences. | Worldwide |
Oleoyl serotonin Quick inquiry Where to buy Suppliers range | Oleoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin, which is a dual antagonist of FAAH/TRPV1 channel. Oleoyl serotonin inhibits capsaicin-induced TRPV1 channel activation (IC50 = 2.57 μM) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC50 > 50 μM). Synonyms: (9Z)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]octadec-9-enamide; N-(2-(5-Hydroxy-1H-indol-3-yl)ethyl)-9Z-octadecenamide. Grades: ≥98%. CAS No. 1002100-44-8. Molecular formula: C28H44N2O2. Mole weight: 440.7. | |
PDDHV Quick inquiry Where to buy Suppliers range | PDDHV is a resiniferatoxin (RTX)-type phorboid vanilloid with capsaicin-like selectivity for the cloned rat vanilloid receptor VR1 (TRPV1). It evoked 45Ca2+-uptake by rat dorsal root ganglion neurons in culture. Synonyms: Phorbol 12,13-didecanoate 20-homovanillate. Grades: ≥99%. CAS No. 179469-40-0. Molecular formula: C49H72O11. Mole weight: 837.1. | |
SB 452533 Quick inquiry Where to buy Suppliers range | SB 452533 is a potent and selective TRPV1 antagonist against capsaicin (pKb = 7.7), noxious heat and acid-mediated (pIC50 = 7.0) receptor activation (pKi = 6.22 at the recombinant hTRPV1 receptor). Synonyms: SB452533; SB 452533; SB-452533. N-(2-Bromophenyl)-N'-[2-[ethyl(3-methylphenyl)amino]ethyl]-urea; 1-(2-bromophenyl)-3-[2-(N-ethyl-3-methylanilino)ethyl]urea. Grades: ≥98% by HPLC. CAS No. 459429-39-1. Molecular formula: C18H22BrN3O. Mole weight: 376.29. | |
SB705498 Quick inquiry Where to buy Suppliers range | SB705498 is a TRPV1 antagonist for hTRPV1, antagonizes capsaicin, acid, and heat activation of TRPV1 with IC50 of 3 nM, 0.1 nM and 6 nM, shows a degree of voltage dependence, exhibits >100-fold selectivity for TRPV1 over TRPM8. Synonyms: SB-705498; SB 705498; SB705498. Grades: >98%. CAS No. 501951-42-4. Molecular formula: C17H16BrF3N4O. Mole weight: 429.23. | |
TRPV4 Antagonist I, RN-1734 (2, 4-Dichloro-N-isopropyl-N- (2-isopropylaminoethyl) benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734) Quick inquiry Where to buy Suppliers range | A cell-permeable benzenesulfonamide compound that selectively antagonizes TRPV4 agonist 4a-PDD-stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9uM, respectively, in HEK293 expressing human, rat, or mouse TRPV4) without affecting the activity of three other human TRP (transient receptor potential) channels, including capsaicin- activated TRPV1, camphor-activated TRPV3, and methanol-activated TRPM8 (IC50 >30uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 946387-07-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Vanillylamine-d3 Hydrochloride Quick inquiry Where to buy Suppliers range | A labeled metabolite of Capsaicin. Group: Biochemicals. Alternative Names: 4-(Aminomethyl)-2-methoxyphenol-d3 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Vanillylamine Hydrochloride Quick inquiry Where to buy Suppliers range | A metabolite of Capsaicin. Group: Biochemicals. Alternative Names: 4-(Aminomethyl)-2-methoxyphenol Hydrochloride. Grades: Highly Purified. CAS No. 7149-10-2. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |