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1,2-Dibenzyloxy-4-(2-hydroxyethyl)benzene is an intermediate in the synthesis of Dopal (D533885), the reactive metabolite of dopamine (D533780), an endogenous catecholamine with α and β-adrenergic activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 96826-11-8. Pack Sizes: 100mg, 1g. Molecular Formula: C22H22O3. US Biological Life Sciences.
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(1-Methylethyl)-normetadrenaline Hydrochloride
(1-Methylethyl)-normetadrenaline hydrochloride is a derivative of normetadrenaline, a metabolite most commonly found in urine. High levels of normetadrenaline in the urine indicate the possibility of having pheochromocytoma, a condition where catecholamineproducing tumors arise from chromaffin cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 1420-27-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C12H20ClNO3, Molecular Weight: 261.75. US Biological Life Sciences.
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2,2'-Dichlorobiphenyl
2,2'-Dichlorobiphenyl is used in biological studies as vesicular catecholamine release from rat PC12 cells on acute and subchronic exposure to polychlorinated biphenyls. Group: Biochemicals. Grades: Highly Purified. CAS No. 13029-08-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C12H8Cl2. US Biological Life Sciences.
2,2-Dimethyl-1,3-benzodioxole-4-acetic Acid Methyl Ester is an intermediate in the synthesis of Dopal (D533885), the reactive metabolite of dopamine (D533780), an endogenous catecholamine with α and β-adrenergic activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 38515-62-7. Pack Sizes: 100mg, 1g. Molecular Formula: C12H14O4. US Biological Life Sciences.
2,3-Bis(4-(benzyloxy)-3-methoxyphenyl)propan-1-amine-d4 is an catecholamine based derivative with potential anti-angiogenic properties. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
2, 4-Dicyano-3- (3, 4-dihydroxy-5-nitrophenyl) -N1, N1, N5, N5-tetraethylpentane diamide is a dimer impurity of Entacapone n (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C21H27N5O6, Molecular Weight: 445.47. US Biological Life Sciences.
2, 4-Dicyano-3- (3, 4-dihydroxyphenyl) -N1, N1, N5, N5-tetraethylpentane diamide is a dimer impurity of Entacapone Vanillin (E558500) and (V097500) respectively. Entacapone acts as a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C21H28N4O4, Molecular Weight: 400.47. US Biological Life Sciences.
2, 4-Dicyano-N1, N1, N5, N5-tetraethyl-3- (4-hydroxy-3-methoxy-5-nitrophenyl) pentanediamide is a dimer impurity of Entacapone Vanillin (E558500) and (V097500) respectively. Entacapone acts as a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C22H29N5O6, Molecular Weight: 459.5. US Biological Life Sciences.
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2-(Benz-d5-hydrylthio)acetamide
2-(Benz-d5-hydrylthio)acetamide is a labeled analogue of modafinil (M482500), an α-1-adrenergic agonist. Modafinil is a CNS stimulant; psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease. Activates phasic dopamine signaling in dorsal and ventral straita (1). Promotes vigilance and wakefulness via modulation of catecholamine / GABAergic neurotransmission (2). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C15H10D5NOS, Molecular Weight: 262.38. US Biological Life Sciences.
(2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide is an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian. Group: Biochemicals. Grades: Highly Purified. CAS No. 857629-79-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C16H19N3O5, Molecular Weight: 333.34. US Biological Life Sciences.
Isotope labelled (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide (C956047), an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C16H14D5N3O5, Molecular Weight: 338.37. US Biological Life Sciences.
2-Hydroxy-2- (3-hydroxy-4-methoxyphenyl) acetonitrile is an intermediate in the synthesis of 3-Hydroxy-4-methoxymandelic Acid (H946345), which is a metabolite of catecholamines. Group: Biochemicals. Grades: Highly Purified. CAS No. 73168-74-8. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H9NO3, Molecular Weight: 179.17. US Biological Life Sciences.
Isotope labelled 2-Methoxy-4-[2-[ (1-methylethyl) amino]ethyl]phenol is an catecholamine based derivative with potential anti-angiogenic properties. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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[3,4-Bis(benzyloxy)phenyl]-1,2-ethanediol
Intermediate in the preparation of Catecholamines metabolites. Group: Biochemicals. Alternative Names: 1-[3, 4-Bis (phenylmethoxy)phenyl]-1, 2-ethanediol; rac 3, 4-Bis (benzyloxy) phenylethylene Glycol. Grades: Highly Purified. CAS No. 100434-10-4. Pack Sizes: 50mg. US Biological Life Sciences.
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[3,4-Bis(benzyloxy)phenyl]-1,2-ethanediol-d5
Intermediate in the preparation of Catecholamines metabolites. Group: Biochemicals. Alternative Names: 1-[3, 4-Bis (phenylmethoxy)phenyl]-1, 2-ethanediol-d5; rac 3, 4-Bis (benzyloxy) phenylethylene Glycol-d5. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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3,4-Dihydroxy-L-phenylalanine
Precursor of catecholamine neurotransmitters; anti-parkinsonian therapy. Natural isomer of the immediate precursor of dopamine; product of tyrsine hydroxylase. Group: Biochemicals. Alternative Names: Levodopa; L-3-Hydroxytyrosine; 3-Hydroxy-L-tyrosine; (-)-3-(3,4-Dihydroxyphenyl)-L-alanine; Bendopa; Deadopa; Dopaflex; Dopal; Dopaidan; Dopalina; Dopar. Grades: Highly Purified. CAS No. 59-92-7. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C9H11NO4, Molecular Weight: 197.19. US Biological Life Sciences.
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3-Hydroxy-4-methoxymandelic Acid
A metabolite of catecholamines. Group: Biochemicals. Alternative Names: α,3-Dihydroxy-4-methoxybenzeneacetic Acid; (RS)-3-Hydroxy-4-methoxymandelic Acid; (+/-)-3-Hydroxy-4-methoxymandelic Acid; 3-Hydroxy-4-methoxymandelic Acid; Isovanilmandelic Acid. Grades: Highly Purified. CAS No. 3695-24-7. Pack Sizes: 100mg. US Biological Life Sciences.
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3-Hydroxy 4-Methoxyphenethylamine HCl
An impurity of Tyramine. Tyramine is a catecholamine releasing agent that binds to both TAAR1 and TAAR2 as an agonist. Tyramine is derived from Tyrosine. Molecular formula: C9H13NO2.HCl. Mole weight: 203.67.
3-Methoxytyramine Glucuronide
An impurity of Tyramine. Tyramine is a catecholamine releasing agent that binds to both TAAR1 and TAAR2 as an agonist. Tyramine is derived from Tyrosine. Molecular formula: C15H21NO8. Mole weight: 343.34.
3-Methoxytyramine Sulfate
An impurity of Tyramine. Tyramine is a catecholamine releasing agent that binds to both TAAR1 and TAAR2 as an agonist. Tyramine is derived from Tyrosine. Synonyms: [4-(2-aminoethyl)-2-methoxyphenyl] hydrogen sulfate; 3-Methyldopamine O-sulfate; CHEBI:133708; 4-(2-aminoethyl)-2-methoxyphenyl hydrogen sulfate. Molecular formula: C9H13NO5S. Mole weight: 247.27.
3-(Pyridin-3'-yl)-cytisine
3-(Pyridin-3'-yl)-cytisine is nicotinic receptor partial agonist that exhibits antidepressant properties. In addition, 3-(Pyridin-3'-yl)-cytisine is able to alter catecholamine homeostasis and response to nicotine in PC12 cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 948027-43-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H17N3O, Molecular Weight: 267.33. US Biological Life Sciences.
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4-Benzyloxy-3-methoxy-toluene-d3
Isotope labelled 4-Benzyloxy-3-methoxy-toluene is an intermediate in the preparations of catecholamine derivatives and fungicides for agricultural purposes. Group: Biochemicals. Alternative Names: 2-Methoxy-4-methyl-1-(phenylmethoxy)benzene-d3. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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4-Hydroxy-3-methoxymandelic Acid
A metabolite of catecholamines. Group: Biochemicals. Alternative Names: α,4-Dihydroxy-3-methoxybenzeneacetic Acid; (+/-)-Vanilmandelic Acid; (4-Hydroxy-3-methoxyphenyl)glycolic Acid; 3-Methoxy-4- hydroxyphenyl hydroxyacetic Acid; HMMA; VMA. Grades: Highly Purified. CAS No. 55-10-7. Pack Sizes: 1g. US Biological Life Sciences.
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4-Hydroxy-3-methoxymandelic Acid-d3
A labeled metabolite of catecholamines. Group: Biochemicals. Alternative Names: α,4-Dihydroxy-3-(methoxy-d3)benzeneacetic Acid; (+/-)-Vanilmandelic Acid-d3; [4-Hydroxy-3-(methoxy-d3)phenyl]glycolic Acid; 3- (Methoxy-d3) -4- hydroxyphenyl hydroxyacetic Acid; HMMA-d3; VMA-d3. Grades: Highly Purified. CAS No. 74495-70-8. Pack Sizes: 10mg. US Biological Life Sciences.
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4-O-Methyldopamine hydrochloride
4-O-Methyldopamine hydrochloride is a catecholamine compound that has an inhibitory effect on dihydropteridine reductase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 645-33-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W041498.
6-Hydroxydopamine hydrobromide
6-Hydroxydopamine hydrobromide is a selective catecholaminergic neurotoxin. 6-Hydroxydopamine hydrobromide is used to produce animal model of Parkinson's disease via causing almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. Uses: Labelled acetophenazine (a163930). antipsychotic. Synonyms: Oxidopamine hydrobromide; 2,4,5-Trihydroxyphenethylamine hydrobromide; 6-OHDA HBr. Grades: 99%. CAS No. 636-00-0. Molecular formula: C8H12BrNO3. Mole weight: 250.09.
6-Hydroxy Dopamine Hydrochloride
6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells. Group: Biochemicals. Alternative Names: 2, 4, 5-Trihydroxyphene thylamine Hydrochloride; 5-(2-Aminoethyl)-1,2,4-benzenetriol Hydrochloride; 6-Hydroxydopamine Hydrochloride; Oxidopamine Hydrochloride; Topamine Hydrochloride. Grades: Highly Purified. CAS No. 28094-15-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
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(6R)-Tetrahydro-L-biopterin-d3 Sulfate(Mixture of Diastereomers)
(6R)-Tetrahydro-L-biopterin-d3 Sulfate(Mixture of Diastereomers) is the labeled R-enantiomer of Tetrahydro-L-biopterin. It is a natural cofactor for phenylalanine hydroxylase, tryptophan hydroxylase, tyrosine hydroxylase, and nitric oxide synthase. An essential cofactor for the production of neurotransmitters such as catecholamines, serotonin, and nitric oxide. Increasing BH4 levels boosts sensitivity to pain. Applications: A natural cofactor for phenylalanine hydroxylase. Group: Coenzymes. CAS No. 103130-44-5 (unlabeled). Mole weight: 342.34. (6R)-Tetrahydro-L-biopterin-d3 Sulfate(Mixture of Diastereomers); 103130-44-5 (unlabeled). Cat No: COEC-090.
(6R)-Tetrahydro-L-biopterin Sulfate
(6R)-Tetrahydro-L-biopterin Sulfate is a natural cofactor for tyrosine hydroxylase, phenylalanine hydroxylase, tryptophan hydroxylase, and nitric oxide synthase. It is also an essential cofactor in the the production of neurotransmitters such as catecholamines, serotonin, and nitric oxide. Applications: An essential cofactor in the the production of neurotransmitters. Group: Coenzymes. CAS No. 103130-44-5. Mole weight: 339.33. Form: Solid. (6R)-Tetrahydro-L-biopterin Sulfate; 103130-44-5. Cat No: COEC-074.
Amrinone
Amrinone (Inamrinone) is a positive inotropic-vasodilator agent. Amrinone is a selective phosphodiesterase III inhibitor that increases cyclic adenosine monophosphate by preventing its breakdown. Amrinone is also an orally active, non-glycosidic and non-catecholamine cardiotonic agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Inamrinone. CAS No. 60719-84-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1294.
(+)-Anabasine hydrochloride
(+)-Anabasine hydrochloride is a nicotine alkaloid present in tobacco products. It is a high affinity neuronal nicotinic ACh receptor partial agonist with Ki values of 0.058, 0.26 and 7.2 μM for rat α7, rat α4β2 and fish skeletal muscle nAChRs respectively. It also stimulates Ca2+-dependent catecholamine release from rat adrenomedullary cells in vitro. It is used as an indicator of smoking or tobacco use. Synonyms: (S)-(+)-3-(2-Piperidinyl)pyridine hydrochloride. Grades: ≥99% by HPLC. CAS No. 53912-89-3. Molecular formula: C10H15N2Cl. Mole weight: 198.69.
Arbutamine
Arbutamine is β-adrenergic receptor originated by SICOR. It is a cardiac stimulant. Arbutamine is a synthetic catecholamine with positive chronotropic and inotropic properties and be applicated in echocardiography and diagnostic coronary angiography. Arbutamine can bind to and activate β-1 adrenergic receptors in the myocardium, so it can increase heart rate and force of myocardial contraction. Arbutamine is an approved drug for the treatment of Coronary artery disease. Uses: Coronary artery disease. Synonyms: Genesa; Arbutaminum; Arbutamina; UNII-B07L15YAEV; CHEBI: 50580; ; 125251-66-3 (Hydrochloride) ; 4-[ (1R) -1-hydroxy-2-[4- (4-hydroxyphenyl) butylamino]ethyl]benzene-1, 2-diol. Grades: 98%. CAS No. 128470-16-6. Molecular formula: C18H23NO4. Mole weight: 317.38.
Bisindolylmaleimide II
Bisindolylmaleimide II is a potent and ATP-competitive inhibitor of protein kinase C (PKC) (IC50 = 0.01 μM). It also displays an antagonistic effect on nicotinic cholinergic receptors (IC50 ~ 0.03 μM for inhibition of catecholamine secretion in nicotine-stimulated PC-12 cells) and an inhibitory effect on PDK1 (IC50 = 14 μM). Synonyms: 3-(1H-Indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione. Grades: ≥97% by HPLC. CAS No. 137592-45-1. Molecular formula: C27H26N4O2. Mole weight: 438.52.
catechol O-methyltransferase
The mammalian enzyme acts more rapidly on catecholamines such as adrenaline or noradrenaline than on catechols. Group: Enzymes. Synonyms: COMT I COMT II; S-COMT (soluble form of catechol-O-methyltransferase); MB-COMT (membrane-bound form of catechol-O-methyltransferase); catechol methyltransferase; catecholamine O-methyltransferase. Enzyme Commission Number: EC 2.1.1.6. CAS No. 9012-25-3. COMT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1961; catechol O-methyltransferase; EC 2.1.1.6; 9012-25-3; COMT I COMT II; S-COMT (soluble form of catechol-O-methyltransferase); MB-COMT (membrane-bound form of catechol-O-methyltransferase); catechol methyltransferase; catecholamine O-methyltransferase. Cat No: EXWM-1961.
Catestatin
Catestatin is a 21-amino acid residue, cationic and hydrophobic peptide. Catestatin is an endogenous peptide that regulates cardiac function and blood pressure [1]. Catestatin is a non-competitive nicotinic antagonist acting through nicotinic acetylcholine receptors (nAChRs) to inhibit catecholamine release [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Catestatin (cattle). CAS No. 142211-96-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1271.
Catestatin (human)
Catestatin, an inhibitory peptide of catecholamine release, corresponds to human chromogranin A (CHGA) 370-390. Reduced catestatin expression may increase the risk of hypertension. In Chga-/- mice rescue of elevated blood pressure to normalcy was achieved by exogenous substitution of catestatin or transgenic expression of human CHGA. Synonyms: H-Ser-Ser-Met-Lys-Leu-Ser-Phe-Arg-Ala-Arg-Ala-Tyr-Gly-Phe-Arg-Gly-Pro-Gly-Pro-Gln-Leu-OH; L-seryl-L-seryl-L-methionyl-L-lysyl-L-leucyl-L-seryl-L-phenylalanyl-L-arginyl-L-alanyl-L-arginyl-L-alanyl-L-tyrosyl-glycyl-L-phenylalanyl-L-arginyl-glycyl-L-prolyl-glycyl-L-prolyl-L-glutaminyl-L-leucine. Grades: ≥95%. CAS No. 197151-46-5. Molecular formula: C104H164N32O27S. Mole weight: 2326.71.
Catestatin (human)
Catestatin human, a catecholamine release-inhibitory peptide, is a pleiotropic peptide involved in cardiovascular protection with its antihypertensive and angiogenic effects. Catestatin human can be used in the study of inflammatory diseases [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Human chromogranin A 352 - 372. CAS No. 197151-46-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3395.
CP22185
CP22185 is a catecholamine-uptake inhibitor. Synonyms: CP-22185; CP 22185; Sertraline hydrochloride specified impurity B; (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine; N-Methyl-4alpha-phenyltetralin-1alpha-amine. Grades: 98%. CAS No. 52758-03-9. Molecular formula: C17H19N. Mole weight: 237.34.
Cyclopentamine Hydrochloride
Cyclopentamine is a sympathomimetic alkylamine that is classified as a vasoconstrictor. Cyclopentamine is a release agent of the catecholamine neurotransmitters norepinephrine (noradrenaline), epinephrine (adrenaline), and dopamine. Synonyms: N,α-Dimethylcyclopentaneethanamine Hydrochloride; N,α-Dimethylcyclopentaneethylamine Hydrochloride; Clopane Hydrochloride; Cyclonarol Hydrochloride; Cyclopentadrin Hydrochloride; Cyclopentadrine Hydrochloride; Cyclopentamin Hydrochloride; Cyklosal Hydrochloride; Cyklosan Hydrochloride; Sinos Hydrochloride. Grades: 95%. CAS No. 538-02-3. Molecular formula: C9H20ClN. Mole weight: 177.72.
Cytidine
Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Cytosine β-D-riboside; Cytosine-1-β-D-ribofuranoside. CAS No. 65-46-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0158.
Dihydro-N-Caffeoyltyramine
An impurity of Tyramine. Tyramine is a catecholamine releasing agent that binds to both TAAR1 and TAAR2 as an agonist. Tyramine is derived from Tyrosine. Synonyms: 3-(3,4-dihydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]propanamide; CHEMBL208465; SCHEMBL2378518. Molecular formula: C17H19NO4. Mole weight: 301.35.
Blocks the effect of catecholamines on ß-receptors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
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DL-Normetanephrine Glucuronide
A derivative of Norepinephrine. Norepinephrine, also known as noradrenaline, is a marker for catecholamine-secreting tumors such as pheochromocytoma, paraganglioma, and neuroblastoma. Synonyms: 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol Glucuronide. Grades: > 95%. Molecular formula: C15H21NO9. Mole weight: 359.34.
D,L-o-Tyrosine (3-(2-hydroxyphenyl)-D,L-alanine)
A precursor in the formation of catecholamines. Group: Biochemicals. Alternative Names: 3-(2-hydroxyphenyl)-D,L-alanine. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
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Dobutamine
Dobutamine is a catecholamine used to treat heart failure by inhibiting β1 receptors in the sympathetic nervous system. Uses: β1- and β2-adrenoceptor agonist with some action at the α1-adrenoceptor. Synonyms: Dobutamina; Dobutrex; (RS)-4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol; (+-) -4- (2- ( (3- (p-Hydroxyphenyl) -1-methylpropyl) amino) ethyl) pyrocatechol. Grades: ≥98%. CAS No. 34368-04-2. Molecular formula: C18H23NO3. Mole weight: 301.38.
Dobutamine hydrochloride
Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 49745-95-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-15746.
Dopamine
Dopamine is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine plays several important roles in the brain and body [1]. Dopamine acts through D2 dopamine receptor s to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: ASL279 free base. CAS No. 51-61-6. Pack Sizes: 10 mM * 1 mL; 10 mg. Product ID: HY-B0451.
Dopamine-d5 hydrochloride
Dopamine-d 5 (hydrochloride) is the deuterium labeled Dopamine (hydrochloride). Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body[1]. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 2193106-55-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0451AS7.
Dopamine HCl
Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals, and a dopamine D1-5 receptors agonist. Synonyms: 4-(2-Aminoethyl)-1,2-benzenediol Hydrochloride; 4-(2-Aminoethyl)pyrocatechol Hydrochloride; 2-(3,4-Dihydroxyphenyl)ethyl-1,1,2,2-amine Hydrochloride. Grades: >98%. CAS No. 62-31-7. Molecular formula: C8H12ClNO2. Mole weight: 189.64.
Dopamine hydrochloride
Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body [1]. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptor s to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: ASL279. CAS No. 62-31-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0451A.
Dopamine Hydrochloride
Endogenous catecholamine with α and β-adrenergic activity. Cardiotonic; antihypotensive. Group: Biochemicals. Alternative Names: 4-(2-Aminoethyl)-1,2-benzenediol Hydrochloride; 4- (2-Aminoethyl) pyrocatechol Hydrochloride. Grades: Highly Purified. CAS No. 62-31-7. Pack Sizes: 1g. US Biological Life Sciences.
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Entacapone
Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC 50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC 50 s>50 μM). Entacapone can be used for the research of Parkinson's disease [1]. Entacapone serves as a inhibitor of FTO demethylation with an IC 50 of 3.5 μM, can be used for the research of metabolic disorders [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130929-57-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14280.
Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian. Group: Biochemicals. Alternative Names: (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide; OR-611; Comtan; Comtess. Grades: Highly Purified. CAS No. 130929-57-6. Pack Sizes: 10mg. US Biological Life Sciences.
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Entacapone-d10
(E)-Isomer of labeled Entacapone polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian. Group: Biochemicals. Alternative Names: (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-di-(ethyl-d5)-2-propenamide; OR-611-d10; Comtan-d10; Comtess-d10. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Felypressin
Felypressin is a Vasopressin 1 agonist and has effects at all Arginine vasopressin receptor 1As. It is a non-catecholamine vasoconstrictor that is chemically related to vasopressin. It is a synthetic hormone characterized by vasoconstrictor properties and is widely used in dental procedures. It has been added to local anesthetic solutions to increase the duration of the anesthetic effect and decrease the risk of toxicity during dental procedures. It is a vasoconstrictor with reduced antidiuretic activity. Synonyms: Octapressin; Octopressin; Phelypressin; Phenylalanine Lysine Vasopressin; PLV-2; Vasopressin, Phenylalanyl-Lysyl; Vasopressin, 2-L-phenylalanine-8-L-lysine-; 2-L-Phenylalanine-8-L-lysinevasopressin; Oxytocin, 2,3-bis(phenylalanine)-8-lysine-; Vasopressin, 2-(phenylalanine)-8-lysine; 2-Phenylalanine-8-lysine-vasopressin; H-Cys(1)-Phe-Phe-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2; L-cysteinyl-L-phenylalanyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide. Grades: >98%. CAS No. 56-59-7. Molecular formula: C46H65N13O11S2. Mole weight: 1040.22.
Felypressin
Felypressin (PLV-2) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin is widely used in dental procedures [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: PLV-2. CAS No. 56-59-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-A0182.
Felypressin acetate
Felypressin acetate (PLV-2 acetate) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin acetate is widely used in dental procedures [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: PLV-2 acetate. CAS No. 914453-97-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0182A.
Felypressin Acetate
Felypressin is a non-catecholamine vasoconstrictor that is chemically related to vasopressin, the posterior pituitary hormone. Synonyms: Vasopressin, 2-L-phenylalanine-8-L-lysine-, acetate (salt); 2-L-Phenylalanine-8-L-lysinevasopressin Acetate (Salt); 2,3-Bis(phenylalanine)-8-lysineoxytocin Acetate; 2-(Phenylalanine)-8-lysinevasopressin Acetate; 2-Phenylalanine-8-lysine-vasopressin Acetate; L-cysteinyl-L-phenylalanyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide acetic acid; H-Cys(1)-Phe-Phe-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2.CH3CO2H. Grades: ≥95%. CAS No. 914453-97-7. Molecular formula: C46H65N13O11S2.xC2H4O2. Mole weight: 1100.3.
Felypressin Impurity A
An impurity of Felypressin. Felypressin is a non-catecholamine vasoconstrictor that is chemically related to vasopressin, the posterior pituitary hormone. Synonyms: H-Cys(N-ethylacetamide)-Phe-Phe-Gln-Asn-Cys(N-ethylacetamide)-Pro-Lys-Gly-Nh2. Grades: > 95%. Molecular formula: C52H77N15O13S2. Mole weight: 1084.47.
Felypressin Impurity B
An impurity of Felypressin. Felypressin is a non-catecholamine vasoconstrictor that is chemically related to vasopressin, the posterior pituitary hormone. Synonyms: H-Cyclo(Cys-Phe-Phe-Gln-Asn-Cys)-Pro-Lys-Gly-Nh2. Grades: > 95%. Molecular formula: C46H66N12O12S2. Mole weight: 1043.29.
Felypressin Impurity C
An impurity of Felypressin. Felypressin is a non-catecholamine vasoconstrictor that is chemically related to vasopressin, the posterior pituitary hormone. Synonyms: Cyclo[H-Cyclo(Cys-Phe-Phe-Gln-Asn-Cys)]-Pro-Lys-Gly-Nh2. Grades: > 95%. Molecular formula: C92H130N26O22S4. Mole weight: 2080.57.
Felypressin Impurity D
An impurity of Felypressin. Felypressin is a non-catecholamine vasoconstrictor that is chemically related to vasopressin, the posterior pituitary hormone. Synonyms: Cyclo[H-Cyclo(Cys-Phe-Phe-Gln-Asn-Cys)]-Pro-Lys-Gly-Nh2. Grades: > 95%. Molecular formula: C92H130N26O22S4. Mole weight: 2080.57.
Felypressin Impurity E
An impurity of Felypressin. Felypressin is a non-catecholamine vasoconstrictor that is chemically related to vasopressin, the posterior pituitary hormone. Synonyms: Aceyl-Cyclo(Cys-Phe-Phe-Gln-Asn-Cys)-Pro-Lys-Gly-Nh2. Grades: > 95%. Molecular formula: C48H67N13O12S2. Mole weight: 1082.33.
Felypressin Impurity F
An impurity of Felypressin. Felypressin is a non-catecholamine vasoconstrictor that is chemically related to vasopressin, the posterior pituitary hormone. Synonyms: H-Cyclo(Cys-Phe-Phe-Gln-Asn-Cys)-Pro-Lys-Gly-Nh2. Grades: > 95%. Molecular formula: C46H64N12O12S2. Mole weight: 1041.27.
Fmoc-3,4-dihydroxy-L-phenylalanine
Fmoc-DOPA is a synthetic derivative of L-DOPA, a naturally occurring amino acid that is a precursor to dopamine and other catecholamines. It is synthesized by attaching a fluorenylmethoxycarbonyl (Fmoc) group to the amino group of DOPA, which results in increased solubility and stability. Fmoc-DOPA has been widely used in peptide synthesis and as a building block in the preparation of bioconjugates due to its unique chemical and physical properties. Uses: Fmoc-dopa has been widely used in peptide synthesis and as a building block in the preparation of bioconjugates. it has also been studied for its potential use in tissue engineering and regenerative medicine, due to its ability to promote cell adhesion and differentiation. fmoc-dopa has also been studied for its potential use in drug delivery, due to its ability to cross the blood-brain barrier. Group: Amino acids. Alternative Names: (R)-Fmoc-nipecotic acid, (R)-N-Fmoc-piperidine-3-carboxylic acid, (r)-fmoc-piperidine-3-carboxylic acid, N-(9-fluorenylmethyloxycarbonyl)-3,4-dihydroxy-L-phenylalanine, (R)-Fmoc-Nip-OH, (r)-1-fmoc-piperidine-3-carboxylic acid, Fmoc-L-DOPA. CAS No. 137018-93-0. Molecular formula: C24H21NO6. Mole weight: 419.4. Purity: Peak Area by HPLC ≥95%. IUPACName: (2S)-3-(3,4-dihydroxyphenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)NC (CC4=CC (=C (C=C4)O)O)C (=O
Fmoc-L-tyrosine
N-Fmoc-L-tyrosine is an N-Fmoc-protected form of L-Tyrosine. L-Tyrosine is an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines in human keratinocytes, and also for the synthesis of proteins and thyroid hormones. Synonyms: Fmoc-L-Tyr-OH; Fmoc-L-Tyrsine; FMOC-TYROSINE; 9-fluorenylmethyloxycarbonyl tyrosine; FMOC-TYR-OH. Grades: ≥ 98% (HPLC). CAS No. 92954-90-0. Molecular formula: C24H21NO5. Mole weight: 403.60.
Guanethidine sulfate
Guanethidine is an antihypertensive drug that reduces the release of catecholamines, such as norepinephrine. It is transported across the sympathetic nerve membrane by the same mechanism that transports norepinephrine itself. Once guanethidine has entered the nerve, it is concentrated in transmitter vesicles, where it replaces norepinephrine.It may also inhibit the release of granules by decreasing norepinephrine. Uses: Sympatholytics. Synonyms: Guanethidine monosulfate. Grades: >98%. CAS No. 645-43-2. Molecular formula: C10H24N4O4S. Mole weight: 296.39.
Heptaminol hydrochloride
Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP-2831 hydrochloride. CAS No. 543-15-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1231.
L-α-Methyltyrosine
L-α-Methyltyrosine is a tyrosine hydroxylase inhibitor. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. It reduces the elevated levels of catecholamines associated with pheochromocytoma, thus preventing hypertension. It significantly inhibits COX-2 activity and has anti-inflammatory and anti-ulcer effects. Uses: L-α-methyltyrosine is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. Synonyms: α-Methyl-L-tyrosine; (S)-2-(4-Hydroxybenzyl)-2-aminopropanoic Acid; (S)-α-Methyltyrosine; Demser; L(-)-Metyrosine; L-α-MT; Metirosine; Racemetirosine; L-α-Methyl-p-tyrosine; Metyrosine. Grades: 98%. CAS No. 672-87-7. Molecular formula: C10H13NO3. Mole weight: 195.21.
L-Noradrenaline
Norepinephrine is the US name for noradrenaline, a catecholamine with multiple roles including as a hormone and a neurotransmitter. It performs its action by being released into the synaptic cleft, where it acts on adrenergic receptors, followed by the signal termination, either by degradation of norepinephrine, or by uptake by surrounding cells. Uses: Adrenergic alpha-agonists. Synonyms: (R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol; l-Arterenol; (-)-α-(Aminomethyl)-3,4-dihydroxy-benzyl Alcohol; 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol; (-)-Arterenol; (-)-Noradrenaline; (-)-Norepinephrine; (-)-α-(Aminomethyl)protocatechuyl Alcohol; (R)-(-)-Norepinephrine; (R)-Noradrenaline; (R)-Norepinephrine; Adrenor; Aktamin; Arterenol; Levarterenol; Levoarterenol; Levonor; Levonoradrenaline; Levonorepinephrine; Levophed; Nor-Epirenan; Noradrenalin; Noradrenaline; Norartrinal; Norepinephrine; Norepirenamine; Sympathin E; l-1-(3,4-Dihydroxyphenyl)-2-aminoethanol; l-2-Amino-1-(3,4-dihydroxyphenyl)ethanol; l-3,4-Dihydroxyphenylethanolamine; l-Arterenol; l-Noradrenaline; l-Norepinephrine; l-α-(Aminomethyl)-3,4-dihydroxybenzyl Alcohol. Grades: >98%. CAS No. 51-41-2. Molecular formula: C8H11NO3. Mole weight: 169.18.
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