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Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 94-41-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-121054.
Chalcone
Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities. Group: other nano materials. CAS No. 94-41-7. Molecular formula: 208.26 g/mol. Mole weight: C15H12O. O=C(/C=C/C1=CC=CC=C1)C2=CC=CC=C2. 98+%.
Isolated from the plant Antirrhinum majus (snapdragon). Involved in the biosynthesis of aurones, plant flavonoids that provide yellow color to the flowers. Group: Enzymes. Synonyms: 4'CGT. Enzyme Commission Number: EC 2.4.1.286. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2519; chalcone 4'-O-glucosyltransferase; EC 2.4.1.286; 4'CGT. Cat No: EXWM-2519.
Chalcone alpha,beta-epoxide
Heterocyclic Organic Compound. Alternative Names: Chalcone alpha,beta-epoxide;1,3-Diphenyl-2,3-epoxy-1-propanone. CAS No. 5411-12-1. Molecular formula: C15H12O2. Catalog: ACM1282702.
chalcone isomerase
This enzyme belongs to the family of isomerases, specifically the class of intramolecular lyases. This enzyme participates in flavonoid biosynthesis. Group: Enzymes. Synonyms: chalcone-flavanone isomerase; flavanone lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.6. CAS No. 9073-57-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5632; chalcone isomerase; EC 5.5.1.6; 9073-57-8; chalcone-flavanone isomerase; flavanone lyase (decyclizing). Cat No: EXWM-5632.
2-Hydroxychalcone
2-Hydroxychalcone is a hydroxyl derivative of chalcones with anticancer activities. 2'-Hydroxychalcone inhibits NF-κB pathway and induces autophagy and apoptosis in breast cancer cells [1]. 2-Hydroxychalcone shows a better antifungal activity against the complex Paracoccidioides spp [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1214-47-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W012349.
3-Deoxysappanchalcone
3-Deoxysappanchalcone is a naturally-occurring chalcone compound isolated from Caesalpinia sappan L. (Leguminosae), which possesses anti-allergic, antiviral, anti-inflammatory and antioxidant activities. 3-Deoxysappanchalcone exerts anti-inflammatory activity via induce heme oxygenase-1 (HO-1) expression by activating the AKT/mTOR pathway in murine macrophages. 3-Deoxysappanchalcone also exhibits anti-influenza virus activity (H3N2, IC50 = 1.06 μM). Group: Inhibitors. CAS No. 112408-67-0. Molecular formula: C16H14O4. Mole weight: 270.28. Appearance: Solid. Purity: 0.9926. Canonical SMILES: O=C (C1=CC=C (O)C=C1OC)/C=C/C2=CC=C (O)C=C2. [ (E)]. Catalog: ACM112408670.
4- (Dimethylamino) chalcone
4- (Dimethylamino) chalcone. Group: Biochemicals. Grades: Reagent Grade. CAS No. 1030-27-9. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity [1]. 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice [2]. Uses: Scientific research. Group: Natural products. CAS No. 20426-12-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-107818.
4'-Hydroxy chalcone
4'-Hydroxy chalcone is a chalcone metabolite with diverse biological activities. It is formed when chalcone is metabolized by the cytochrome (CYP) P450 isoform CYP1A1 or CYP2C6. 4'-Hydroxychalcone is a chalone derivative that exhibits moderate to good antiviral activity against tobacco mosaic virus (TMV). Synonyms: 2-Benzal-4'-hydroxyacetophenone; 2-Benzylidene-4'-hydroxyacetophenone; p-Cinnamoylphenol; NSC 242264; 4'-Hydroxychalcone. Grades: ≥98%. CAS No. 2657-25-2. Molecular formula: C15H12O2. Mole weight: 224.3.
4'-O-Methylbavachalcone
4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM. Group: Inhibitors. CAS No. 20784-60-5. Molecular formula: C21H22O4. Mole weight: 338.4. Appearance: Solid. Purity: 0.9985. Canonical SMILES: O=C (C1=CC (C/C=C (C)\C)=C (OC)C=C1O)/C=C/C2=CC=C (O)C=C2. Catalog: ACM20784605.
Bis (3, 4-methylenedioxy) chalcone
Bis (3, 4-methylenedioxy) chalcone. Group: Biochemicals. Alternative Names: 1,3-Bis(1,3-benzodioxol-5-yl)-2-propen-1-one. Grades: Highly Purified. CAS No. 76530-89-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C17H12O5. US Biological Life Sciences.
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Glycyrrhiza chalcone A
Glycyrrhiza chalcone A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 58749-22-7. Molecular Formula: C21H22O4. Mole Weight: 338.4. Catalog: APB58749227.
Hesperidin methylchalcone
Hesperidin methylchalcone (Hesperidin methyl chalcone) is an orally active flavonoid that has analgesic, anti-inflammatory and antioxidant properties. Hesperidin methylchalcone exhibits vasoprotective activity. Hesperidin methylchalcone inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone can be used for the research of gout disease [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 24292-52-2. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-126382.
Hesperidin methyl chalcone
Hesperidin methyl chalcone (CAS# 24292-52-2) is a flavonoid agent used in the treatment of venous insufficiency. Synonyms: (E)-3-(3-hydroxy-4-methoxyphenyl)-1-[2-hydroxy-6-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxyphenyl]prop-2-en-1-one. Grades: 95% UV. CAS No. 24292-52-2. Molecular formula: C29H36O15. Mole weight: 624.59.
Isobavachalcone is a naturally occurring chalcone mainly isolated from the seeds of Psoralea corylifolia Linn. Isobavachalcone inhibits Akt signaling pathway, inducing apoptosis in human cancer cells. Uses: Anti-inflammatory. Synonyms: Corylifolinin; Isobacachalcone. Grades: >98%. CAS No. 20784-50-3. Molecular formula: C20H20O4. Mole weight: 324.37.
Naringenin chalcone
Naringenin chalcone is a natural chalconoid that can be isolated from tomato skin. It exhibits antioxidant, anti-inflammatory, and anti-allergic properties. Synonyms: Chalconaringenin; Isosalipurpol; trans-2'4'6'4-tetrahydroxychalcone. CAS No. 73692-50-9. Molecular formula: C15H12O5. Mole weight: 272.25.
Naringenin chalcone
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. Naringenin chalcone induces Apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 73692-50-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N3007.
Naringenin Chalcone
Formula: Group: Biochemicals. Grades: Plant Grade. CAS No. 73692-50-9. Pack Sizes: 20mg. US Biological Life Sciences.
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naringenin-chalcone synthase
In the presence of NADH and a reductase, 6'-deoxychalcone is produced. Group: Enzymes. Synonyms: chalcone synthase; flavanone synthase; 6'-deoxychalcone synthase; chalcone synthetase; DOCS; CHS. Enzyme Commission Number: EC 2.3.1.74. CAS No. 56803-04-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2254; naringenin-chalcone synthase; EC 2.3.1.74; 56803-04-4; chalcone synthase; flavanone synthase; 6'-deoxychalcone synthase; chalcone synthetase; DOCS; CHS. Cat No: EXWM-2254.
Neohesperidin dihydrochalcone
Neohesperidin dihydrochalcone is a synthetic glycoside chalcone, is added to various foods and beverages as a low caloric artificial sweetener. Uses: Scientific research. Group: Natural products. Alternative Names: Neohesperidin DC; NHDC. CAS No. 20702-77-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0154.
trans-Chalcone
trans-Chalcone. Group: Biochemicals. Grades: Highly Purified. CAS No. 614-47-1. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C15H12O. US Biological Life Sciences.
Worldwide
trans-Chalcone
trans-Chalcone, isolated from Aronia melanocarpa skin, is a biphenolic core structure of flavonoids precursor. trans-Chalcone is a potent fatty acid synthase (FAS) and α-amylase inhibitor. trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7. trans-Chalcone has antifungal and anticancer activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 614-47-1. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-Y0598.
Trans-Chalcone
trans-Chalcone, isolated from Aronia melanocarpa skin, is a biphenolic core structure of flavonoids precursor. trans-Chalcone is a potent fatty acid synthase (FAS) and α-amylase inhibitor. trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7. trans-Chalcone has antifungal and anticancer activity. Group: Inhibitors. Alternative Names: Phenyltrans-styrylketone. CAS No. 614-47-1. Molecular formula: C15H12O. Mole weight: 208.26. Appearance: Pale yellow solid. Purity: 0.95. IUPACName: (E)-1,3-Diphenylprop-2-en-1-one. Canonical SMILES: C1=CC=C(C=C1)C=CC(=O)C2=CC=CC=C2. Density: 1.0712 g/cm³. ECNumber: 210-383-8. Catalog: ACM614471.
[1, 1'-Bis (di-tert-butylphosphino)ferrocene]palladium (II) Dichloride
1,1'-Bis (di-t-butylphosphino)ferrocene palladium dichloride is used as a catalyst for the preparation of chalcones. Group: Palladium series catalysts. Alternative Names: PdCl2(dtbpf). CAS No. 95408-45-0. Molecular formula: C26H44Cl2FeP2Pd. Mole weight: 651.75. Appearance: dark red crystals. Purity: Pd ≥16.3%. IUPACName: Dichloro[1, 1-Bis (di-Tert-Butylphosphino)Ferrocene]Palladium (II). Catalog: ACM95408450.
1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one is a chalcone compound used as a selective inhibitor of breast cancer resistance protein. Group: Biochemicals. Grades: Highly Purified. CAS No. 53350-27-9. Pack Sizes: 25mg, 50mg. Molecular Formula: C20H22O7. US Biological Life Sciences.
Worldwide
1-Bromo-3-methyl-2-butene (90%)
1-Bromo-3-methyl-2-butene is used to prepare xanthine dipeptidyl peptidase inhibitors for treatment of type 2 diabetes. It can also be used to synthesize natural and non-natural prenylated chalcones with antitumor, antioxidant activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 870-63-3. Pack Sizes: 1g, 5g. Molecular Formula: C5H9Br, Molecular Weight: 149.03. US Biological Life Sciences.
Worldwide
1-Phenyl-2-buten-1-one
1-Phenyl-2-buten-1-one is used in the preparation of chalcones derivatives and analogs and for the testing of their antimicrobial activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 495-41-0. Pack Sizes: 500mg, 1g. Molecular Formula: C10H10O, Molecular Weight: 146.19. US Biological Life Sciences.
2,2'-[1,3-Phenylenebis(4,5-dihydro-1H-pyrazole-5,3-diyl)]bis-phenol is used in the synthetic preparation of bis(pyrazolines) by cyclization of bis(chalcones) with hydrazine. Group: Biochemicals. Grades: Highly Purified. CAS No. 528599-50-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C24H22N4O2, Molecular Weight: 398.46. US Biological Life Sciences.
Worldwide
2,4-Dihydroxy-6-methoxyacetophenone
2,4-Dihydroxy-6-methoxyacetophenone is a reagent that is used in the preparation of polysubstituted synthetic chalcones. Group: Biochemicals. Grades: Highly Purified. CAS No. 3602-54-8. Pack Sizes: 250mg, 2.5g. Molecular Formula: C9H10O4, Molecular Weight: 182.17. US Biological Life Sciences.
Worldwide
2,4-Dihydroxy-6-methoxyacetophenone-d3
2,4-Dihydroxy-6-methoxyacetophenone-d3 is the isotope labelled analog of 2,4-Dihydroxy-6-methoxyacetophenone. 2,4-Dihydroxy-6-methoxyacetophenone is a reagent that is used in the preparation of polysubstituted synthetic chalcones. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C9H7D3O4, Molecular Weight: 185.19. US Biological Life Sciences.
Worldwide
2-Acetylthiophene
2-Acetylthiophene is used in the synthesis of organoboranes as well as chalcone derivatives as anti-inflammatories. Group: Biochemicals. Alternative Names: 1-(2-Thienyl)ethanone; 1-(2-Thienyl)-1-ethanone; 1-(2-Thienyl)ethanone; 1-(Thiophen-2-yl)ethanone; 2-Acetothienone; 2-Acetothiophene; 2-Acetylthiophene; 2-Thienyl methyl ketone; Methyl 2-thienyl ketone; NSC 2345; α-Acetylthiophene. Grades: Highly Purified. CAS No. 88-15-3. Pack Sizes: 25g. US Biological Life Sciences.
Worldwide
2-Acetylthiophene
2-Acetylthiophene is used in the synthesis of organoboranes as well as chalcone derivatives as anti-inflammatories. Group: Thiophenes. Alternative Names: Methyl 2-thienyl ketone. CAS No. 88-15-3. Molecular formula: C6H6OS. Mole weight: 126.18. Appearance: Yellow to brown liquid. Density: 1.16. ECNumber: 201-804-6. Catalog: ACM88153.
(2E)-1-(2-Hydroxyphenyl)-3-phenyl-2-propen-1-one
A synthetic chalcone with antibacterial and potential antitumoral activity. Group: Biochemicals. Alternative Names: (E)-2'-Hydroxy-chalcone; (E)-o-Hydroxyphenyl Styryl Ketone; NSC 170284; trans-2'-Hydroxychalcone. Grades: Highly Purified. CAS No. 888-12-0. Pack Sizes: 2.5g. US Biological Life Sciences.
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2-Naphthalene carboxaldehyde
2-Naphthalene carboxaldehyde is used to prepare chalcone analogs with increased antileishmanial activities. It is also used to synthesize (aryl) (oxo) spiro[cyclopropane-1, 3'-indole] derivatives with their activities as HIV-1 non-nucleoside reverse transcriptase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 66-99-9. Pack Sizes: 5g, 25g. Molecular Formula: C11H8O. US Biological Life Sciences.
2-Sulfobenzaldehyde, is used for the synthesis of a series of novel 3-[N, N-bis(2-hydroxyethyl)-amino]-chalcone derivatives, having antimicrobial activity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g, 10g. Molecular Formula: C7H6O4S; xH2O. US Biological Life Sciences.
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3,4-Dimethoxybenzaldehyde
3,4-Dimethoxybenzaldehyde. Synonyms: Methylvanillin, NSC 24521, NSC 8500, Vanillin methyl ether, Veratraldehyde. CAS No. 120-14-9. Pack Sizes: 5, 100, 500 g in poly bottle. Product ID: CDC10-0173. Molecular formula: (CH3O)2C6H3CHO. Category: Flavoring Chemical Agents. Product Keywords: Cosmetic Ingredients; Flavoring Chemical Agents; 3,4-Dimethoxybenzaldehyde; CDC10-0173; 120-14-9; (CH3O)2C6H3CHO; Methylvanillin, NSC 24521, NSC 8500, Vanillin methyl ether, Veratraldehyde; 204-373-2; MFCD00003363; 120-14-9. Purity: 0.99. Color: White to yellow. EC Number: 204-373-2. Physical State: Solid. Solubility: alcohol: freely soluble. Quality Level: 100. Storage: 2-8°C. Application: 3,4-Dimethoxybenzaldehyde was used in the preparation of 4-chloromethyl-2-(dimethoxyphenyl)-1,3-dioxolane. It was used in the synthesis of (+)-lithospermic acid, having anti-HIV activity. Boiling Point: 281 °C (lit.). Melting Point: 40-43 °C (lit.). Density: 1.1708 (rough estimate). Product Description: 3,4-Dimethoxybenzaldehyde forms 1:1 inclusion complexes with cyclodextrins. It reacts with 3-acetyl-2,5-dimethythiophene to yield chalcone dye, (2E)-3-(3,4-Dimethoxyphenyl)-1-(2,5-dimethylthiophen-3-yl)prop-2-en-1-one.
3-Acetyl-5-chloro-2-thiophenesulfonamide
3-Acetyl-5-chloro-2-thiophenesulfonamide is a reactant used in the preparation of heteroaryl chalcones as potent antimicrobial agents and Brinzolamide (B677600), a topical carbonic anhydrase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 160982-10-5. Pack Sizes: 250mg. US Biological Life Sciences.
3-Chloro-N-(1-methylethyl)-benzenemethanamine-d7 Hydrochloride is derived from 3-Chlorobenzaldehyde (C364495), which is a chemical reagent used in synthesis of y-butyrolactones. Also, used in the synthesis of chalcones and flavonoids with inhibitory activity toward Tuberculosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H7D7ClN HCl, Molecular Weight: 190.723646. US Biological Life Sciences.
Worldwide
3'-Hydroxyacetophenone
An impurity of Etilefrin. Etilefrin is a sympathomimetic drug that increases the pulse rate, cardiac output, stroke volume, central venous pressure and mean arterial pressure of healthy individuals. Uses: 3'-hydroxyacetophenone is a chemical reagent used in the synthesis and preparation of chalcones and flavonoids as anti-tuberculosis agents, as well as antileishmanial chaocones. Synonyms: 1-(3-hydroxyphenyl)ethanone. Grades: > 95 %. CAS No. 121-71-1. Molecular formula: C8H8O2. Mole weight: 136.15.
3-Hydroxyacetophenone
3-Hydroxyacetophenone is a chemical reagent used in the synthesis and preparation of chalcones and flavonoids as anti-tuberculosis agents, as well as antileishmanial chaocones. Group: Biochemicals. Alternative Names: 1- (3-Hydroxyphenyl) ethanone; 3'-Hydroxyacetophenone; 1- (3-Hydroxyphenyl) ethanone; 3-Acetylphenol; 3-Hydroxyphenylethanone; 3'-Hydroxyacetophenone; A 0104; NSC 2440; m-Acetylphenol; m-Hydroxyacetophenone. Grades: Highly Purified. CAS No. 121-71-1. Pack Sizes: 25g. US Biological Life Sciences.
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6-Methoxy-1-tetralone
6-Methoxy-1-tetralone is a reagent useful in the synthesis of (2-(furanyl)vinyl)-1-tetralone chalcones which possesses anticancer agents and inducers of apoptosis. Group: Biochemicals. Alternative Names: 3,4-Dihydro-6-methoxy-1(2H)-naphthalenone; 1,2,3,4-Tetrahydro-6-methoxy-1-naphthalenone; 1-Oxo-1,2,3,4-tetrahydro-6-methoxynaphthalene; 6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-one; 6-Methoxy-1-oxo-1,2,3,4-tetrahydronaphthalene; 6-Methoxy-3,4-dihydro-1(2H)-naphthalenone; 6-Methoxy-3,4-dihydro-2H-naphthalen-1-one; 6-Methoxy-3,4-dihydronaphthalene-1(2H)-one; 6-Methoxy-α-tetralone; NSC 41700. Grades: Highly Purified. CAS No. 1078-19-9. Pack Sizes: 50g, 100g, 250g, 500g. Molecular Formula: C??H??O?, Molecular Weight: 176.21. US Biological Life Sciences.
Worldwide
acridone synthase
Belongs to a superfamily of plant polyketide synthases. Has many similarities to chalcone and stilbene synthases (see reaction synthesis). Group: Enzymes. Enzyme Commission Number: EC 2.3.1.159. CAS No. 99085-53-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2098; acridone synthase; EC 2.3.1.159; 99085-53-7. Cat No: EXWM-2098.
Butein
Butein is a cAMP-specific PDE inhibitor with an IC 50 of 10.4 μM for PDE4 [1]. Butein is a specific protein tyrosine kinase inhibitor with IC 50 s of 16 and 65 μM for EGFR and p60 c-src in HepG2 cells [2]. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a [3]. Butein is a SIRT1 activator (STAC). Uses: Scientific research. Group: Natural products. Alternative Names: 2,3,4,4-tetrahydroxy Chalcone. CAS No. 487-52-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16558.
Cardamonin
Cardamonin can be found from cardamom, and can target various signaling molecules, transcriptional factors, cytokines and enzymes. Cardamonin can inhibit mTOR , NF-κB , Akt , STAT3 , Wnt/β-catenin and COX-2. Cardamonin shows anticancer, anti-inflammatory, antimicrobial and antidiabetic activities [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cardamomin; Alpinetin chalcone. CAS No. 18956-16-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0279.
Diethyl Bromomalonate
Diethyl Bromomalonate is a chemical constituent of the asymmetric cyclopropanation of chalcones. Also used in the preparation of nanaplatforms for NIR imaging-guided photodynamic therapy of cancer cells. Group: Biochemicals. Alternative Names: Bromomalonic Acid Diethyl Ester; 2-Bromomalonic Acid Diethyl Ester; Diethyl 2-bromo-1,3-propanedioate; Diethyl 2-Bromomalonate; Diethyl 2-bromopropanedioate; Diethyl Bromomalonate; Diethyl α-Bromomalonate; Ethyl Bromomalonate; NSC 1985; α-Bromomalonic Ester. Grades: Highly Purified. CAS No. 685-87-0. Pack Sizes: 50g. US Biological Life Sciences.
Worldwide
Flavokawain A
Flavokawain A, a proming anticarcinogenic agent , is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer [1]. Uses: Scientific research. Group: Natural products. CAS No. 3420-72-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N2420.
Flavokawain B
Flavokawain B (Flavokavain B) is an orally active chalcone. Flavokawain B results in activation of caspase-9, -3 and -8 , cleavage of PARP. Flavokawain B down-regulates Bcl-2 with concomitant increase in Bax level. Flavokawain B inhibits NF-κB , PI3K/Akt and MAPK signaling pathway. Flavokawain B exhibits Apoptotic effects. Flavokawain B inhibits MMP-9 and promotes ROS generation. Flavokawain B inhibits multiple tumors and inflammation [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] [13]. Uses: Scientific research. Group: Natural products. Alternative Names: Flavokavain B. CAS No. 1775-97-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2132.
Flavokawain C
Flavokawain C is a chalcone isolated from Piper methysticum Forst. Synonyms: Flavokavain C; Flavokawin C. Grades: 98%. CAS No. 37308-75-1. Molecular formula: C17H16O5. Mole weight: 300.3.
Homobutein
Homobutein a natural chalcones (can be found in many medicinal plants, fruits, vegetables, spices and nuts), is a potent HDACs/NF-κB dual inhibitor with IC50s of 190 and 38 μM, respectively. Homobutein also a chelator of iron (II and III) cations, shows various activities, including anticancer, anti-inflammatory, antiparasite and antioxidation. Group: Inhibitors. Alternative Names: 2',4,4'-TRIHYDROXY-3-METHOXY CHALCONE;3-METHOXY-2',4',4-TRIHYDROXYCHALCONE;HOMOBUTEIN;(E)-2',4,4'-trihydroxy-3-methoxychalcone;3-O-methylbutein;HOMOBUTEIN WITH HPLC;HOMOBUTEIN hplc;(E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-one. CAS No. 34000-39-0. Molecular formula: C16H14O5. Mole weight: 286.3. Appearance: Powder. Purity: 0.98. IUPACName: (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one. Canonical SMILES: COC1=C (C=CC (=C1)C=CC (=O)C2=C (C=C (C=C2)O)O)O. Density: 1.369 g/cm³. ECNumber: 251-782-7. Catalog: ACM34000390.
Isoliquiritigenin
Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μM. Group: Inhibitors. Alternative Names: 2',4,4'-Trihydroxy-trans-chalcone. CAS No. 961-29-5. Molecular formula: C15H12O4. Mole weight: 256.25. Appearance: Yellow to orange powder. Purity: 0.98. IUPACName: (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one. Canonical SMILES: C1=CC (=CC=C1C=CC (=O)C2=C (C=C (C=C2)O)O)O. Density: 1.384±0.06 g/cm³. Catalog: ACM961295.
isoliquiritigenin 2'-O-methyltransferase
Not identical to EC 2.1.1.65, licodione 2'-O-methyltransferase. While EC 2.1.1.154, isoliquiritigenin 2'-O-methyltransferase can use licodione as a substrate, EC 2.1.1.65 cannot use isoliquiritigenin as a substrate. Group: Enzymes. Synonyms: chalcone OMT; CHMT. Enzyme Commission Number: EC 2.1.1.154. CAS No. 139317-14-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1750; isoliquiritigenin 2'-O-methyltransferase; EC 2.1.1.154; 139317-14-9; chalcone OMT; CHMT. Cat No: EXWM-1750.
Loureirin D
Loureirin D is a chalcone isolated from Dracaena cochinchinensis. Grades: 98%. CAS No. 119425-91-1. Molecular formula: C16H16O5. Mole weight: 288.29.
phloroisovalerophenone synthase
Closely related to EC 2.3.1.74, naringenin-chalcone synthase. The product, 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one, is phloroisovalerophenone. Also acts on isobutyryl-CoA as substrate to give phlorisobutyrophenone. The products are intermediates in the biosynthesis of the bitter (α) acids in hops (Humulus lupulus). Group: Enzymes. Synonyms: valerophenone synthase; 3-methyl-1-(trihydroxyphenyl)butan-1-one synthase. Enzyme Commission Number: EC 2.3.1.156. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2095; phloroisovalerophenone synthase; EC 2.3.1.156; valerophenone synthase; 3-methyl-1-(trihydroxyphenyl)butan-1-one synthase. Cat No: EXWM-2095.
pinosylvin synthase
Not identical with EC 2.3.1.74 (naringenin-chalcone synthase) or EC 2.3.1.95 (trihydroxystilbene synthase). Group: Enzymes. Synonyms: stilbene synthase (ambiguous); pine stilbene synthase (ambiguous). Enzyme Commission Number: EC 2.3.1.146. CAS No. 72994-49-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2085; pinosylvin synthase; EC 2.3.1.146; 72994-49-1; stilbene synthase (ambiguous); pine stilbene synthase (ambiguous). Cat No: EXWM-2085.
Tetrabutylammonium Tribromide
Tetrabutylammonium Tribromide is used in the synthesis of antimicrobial agents via chalcones. Also used in the synthesis of potent tubulin polymerization inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 38932-80-8. Pack Sizes: 10g, 25g, 50g, 100g. Molecular Formula: C??H??Br?N, Molecular Weight: 482.18. US Biological Life Sciences.
Worldwide
trihydroxystilbene synthase
Not identical with EC 2.3.1.74 naringenin-chalcone synthase or EC 2.3.1.146 pinosylvin synthase. Group: Enzymes. Synonyms: resveratrol synthase; stilbene synthase (ambiguous). Enzyme Commission Number: EC 2.3.1.95. CAS No. 128449-70-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2277; trihydroxystilbene synthase; EC 2.3.1.95; 128449-70-7; resveratrol synthase; stilbene synthase (ambiguous). Cat No: EXWM-2277.
Catalyst used for an asymmetric Michael addition. Catalyst used for an asymmetric Michael addition of 1,3-dicarbonyls to enones. Catalyst used for the asymmetric aza-Michael addition of methylhydroxylamine to chalcone derivatives. Catalyst used for the asymmetric direct aldol reaction of acetophenone and pivaldehyde. Group: Lanthanum catalysts. Alternative Names: Hydron;lanthanum(3+);1-(2-oxidonaphthalen-1-yl)naphthalen-2-olate;1,1,3,3-tetramethylguanidine. CAS No. 1611526-71-6. Molecular formula: C65H50LaN3O6. Mole weight: 1108.01. Appearance: Tan powder. Purity: 0.98. Canonical SMILES: [H+]. CN (C)C (=N)N (C)C. C1=CC=C2C (=C1)C=CC (=C2C3=C (C=CC4=CC=CC=C43)[O-])[O-]. C1=CC=C2C (=C1)C=CC (=C2C3=C (C=CC4=CC=CC=C43)[O-])[O-]. C1=CC=C2C (=C1)C=CC (=C2C3=C (C=CC4=CC=CC=C43)[O-])[O-]. [La+3]. Catalog: ACM1611526716-1.
Catalyst used for an asymmetric Michael addition. Catalyst used for an asymmetric Michael addition of 1,3-dicarbonyls to enones. Catalyst used for the asymmetric aza-Michael addition of methylhydroxylamine to chalcone derivatives. Catalyst used for the asymmetric direct aldol reaction of acetophenone and pivaldehyde. Group: Ytterbium catalysts. Alternative Names: hydron;1-(2-oxidonaphthalen-1-yl)naphthalen-2-olate;1,1,3,3-tetramethylguanidine;ytterbium(3+). CAS No. 1611526-75-0. Molecular formula: C75H78N9O6Yb. Mole weight: 1374.52. Appearance: Off-white to pale yellow powder. Purity: 0.97. Canonical SMILES: [H+]. [H+]. [H+]. CN (C)C (=N)N (C)C. CN (C)C (=N)N (C)C. CN (C)C (=N)N (C)C. C1=CC=C2C (=C1)C=CC (=C2C3=C (C=CC4=CC=CC=C43)[O-])[O-]. C1=CC=C2C (=C1)C=CC (=C2C3=C (C=CC4=CC=CC=C43)[O-])[O-]. C1=CC=C2C (=C1)C=CC (=C2C3=C (C=CC4=CC=CC=C43)[O-])[O-]. [Yb+3]. Catalog: ACM1611526750-1.
Catalyst used for an asymmetric Michael addition. Catalyst used for an asymmetric Michael addition of 1,3-dicarbonyls to enones. Catalyst used for the asymmetric aza-Michael addition of methylhydroxylamine to chalcone derivatives. Catalyst used for the asymmetric direct aldol reaction of acetophenone and pivaldehyde. Group: Yttrium catalysts. CAS No. 1611526-73-8. Molecular formula: C75H78N9O6Y. Mole weight: 1290.39. Appearance: Orange powder. Catalog: ACM1611526738-1.
Xanthoangelol
Xanthoangelol is a chalcone isolated from Ashitaba with anti-inflammatory, anti-platelet and antibacterial activities. Uses: Proton pump inhibitors. Synonyms: Xanthoangelol; 62949-76-2; (E)-1-[3-[(2E)-3,7-dimethylocta-2,6-dienyl]-2,4-dihydroxyphenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one; UNII-91D4GN26Z1MLS000574837. Grades: 98%. CAS No. 62949-76-2. Molecular formula: C25H28O4. Mole weight: 392.5.
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