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Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 94-41-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-121054.
Chalcone
Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities. Group: other nano materials. CAS No. 94-41-7. Molecular formula: 208.26 g/mol. Mole weight: C15H12O. O=C(/C=C/C1=CC=CC=C1)C2=CC=CC=C2. 98+%.
Chalcone 4 (hydrate)
Chalcone 4 hydrate is an antiparasite agent that inhibits the growth of Babesia and Theileria. Synonyms: (E)-1-(4-Chlorophenyl)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-one hydrate. CAS No. 1202866-96-3. Molecular formula: C16H15ClO4. Mole weight: 306.74.
chalcone 4'-O-glucosyltransferase
Isolated from the plant Antirrhinum majus (snapdragon). Involved in the biosynthesis of aurones, plant flavonoids that provide yellow color to the flowers. Group: Enzymes. Synonyms: 4'CGT. Enzyme Commission Number: EC 2.4.1.286. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2519; chalcone 4'-O-glucosyltransferase; EC 2.4.1.286; 4'CGT. Cat No: EXWM-2519.
Chalcone,a,b-dichloro-,dimethyl acetal(8ci)
Chalcone,a,b-dichloro-,dimethyl acetal(8ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: NSC172576, AC1NTLJC, NSC-172576, [(E)-1,2-dichloro-3,3-dimethoxy-3-phenylprop-1-enyl]benzene, 13492-69-8. Product Category: Heterocyclic Organic Compound. CAS No. 13492-69-8. Molecular formula: C17H16Cl2O2. Mole weight: 323.2137. Purity: 0.96. IUPACName: [(E)-1,2-dichloro-3,3-dimethoxy-3-phenylprop-1-enyl]benzene. Canonical SMILES: COC(C1=CC=CC=C1)(C(=C(C2=CC=CC=C2)Cl)Cl)OC. Density: 1.225g/cm³. Product ID: ACM13492698. Alfa Chemistry ISO 9001:2015 Certified.
chalcone isomerase
This enzyme belongs to the family of isomerases, specifically the class of intramolecular lyases. This enzyme participates in flavonoid biosynthesis. Group: Enzymes. Synonyms: chalcone-flavanone isomerase; flavanone lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.6. CAS No. 9073-57-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5632; chalcone isomerase; EC 5.5.1.6; 9073-57-8; chalcone-flavanone isomerase; flavanone lyase (decyclizing). Cat No: EXWM-5632.
2',4',6',3,4-Pentahydroxychalcone
2',4',6',3,4-Pentahydroxychalcone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ERIODICTYOL CHALCONE;2',4',6',3,4-PENTAHYDROXYCHALCONE;3,4,2',4',6'-PENTAHYDROXYCHALCONE;PENTAHYDROXYCHALCONE,2',4',6',3,4-;2',3,4,4',6'-pentahydroxychalcone;3-(3,4-Dihydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-2-propen-1-one;Eriodictyol chalocone. Product Category: Heterocyclic Organic Compound. CAS No. 73692-51-0. Molecular formula: C15H12O6. Mole weight: 288.25. Product ID: ACM73692510. Alfa Chemistry ISO 9001:2015 Certified.
2'-Hydroxy-2-methoxychalcone
2'-Hydroxy-2-methoxychalcone is a synthetic chalcone with antimicrobial activity. Synonyms: 1-(2-hydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one; (E)-2'-Hydroxy-2-methoxychalcone. CAS No. 42220-77-9. Molecular formula: C16H14O3. Mole weight: 254.28.
2'-HYDROXY-3,4,5,6'-TETRAMETHOXYCHALCONE
2-Hydroxy-3,4,5,6-tetramethoxychalcone is a natural chalcone found in the herbs of Fissistigma bracteolatum. Synonyms: (2E)-3-(2-Hydroxy-3,4,5,6-tetramethoxyphenyl)-1-phenyl-2-propen-1-one; 3-(2-Hydroxy-3,4,5,6-tetraMethoxyphenyl)-1-phenylprop-2-en-1-one. Grade: >98%. CAS No. 219298-74-5. Molecular formula: C19H20O6. Mole weight: 344.36.
2-Hydroxychalcone
2-Hydroxychalcone is a hydroxyl derivative of chalcones with anticancer activities. 2'-Hydroxychalcone inhibits NF-κB pathway and induces autophagy and apoptosis in breast cancer cells [1]. 2-Hydroxychalcone shows a better antifungal activity against the complex Paracoccidioides spp [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1214-47-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W012349.
3-Deoxysappanchalcone
3-Deoxysappanchalcone is a naturally-occurring chalcone compound isolated from Caesalpinia sappan L. (Leguminosae), which possesses anti-allergic, antiviral, anti-inflammatory and antioxidant activities. 3-Deoxysappanchalcone exerts anti-inflammatory activity via induce heme oxygenase-1 (HO-1) expression by activating the AKT/mTOR pathway in murine macrophages. 3-Deoxysappanchalcone also exhibits anti-influenza virus activity (H3N2, IC50 = 1.06 μM). Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 112408-67-0. Molecular formula: C16H14O4. Mole weight: 270.28. Purity: 0.9926. Canonical SMILES: O=C(C1=CC=C(O)C=C1OC)/C=C/C2=CC=C(O)C=C2.[(E)]. Product ID: ACM112408670. Alfa Chemistry ISO 9001:2015 Certified.
4,4'-DIHYDROXY-2-METHOXYCHALCONE
Echinatin is extracted from the root of Glycyrrhiza glabra L. It inhibits DNP-ATPase activity while stimulating range latent ATPase activity in the low concentration. It disturbs the mitochondrial energy transfer reactions and membrane permeability. It was demonstrated to inhibit the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells. Synonyms: (E)-3-(4-Hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; (E)-4,4'-Dihydroxy-2-methoxychalcone; 4,4'-Dihydroxy-2-methoxy-trans-chalcone; 4'-Dihydroxy-2-Methoxychalcone; Retrochalcone. Grade: >98%. CAS No. 34221-41-5. Molecular formula: C16H14O4. Mole weight: 270.28.
4- (Dimethylamino) chalcone
4- (Dimethylamino) chalcone. Group: Biochemicals. Grades: Reagent Grade. CAS No. 1030-27-9. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
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4-Hydroxychalcone
4-Hydroxychalcone is a chalcone metabolite and inhibitor of TNFα-induced NF-κB pathway activation. It suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity. Synonyms: 4-hydroxy chalcone. Grade: 95%. CAS No. 20426-12-4. Molecular formula: C15H12O2. Mole weight: 224.25.
4-Hydroxychalcone
4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity [1]. 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice [2]. Uses: Scientific research. Group: Natural products. CAS No. 20426-12-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-107818.
4'-Hydroxy chalcone
4'-Hydroxy chalcone is a chalcone metabolite with diverse biological activities. It is formed when chalcone is metabolized by the cytochrome (CYP) P450 isoform CYP1A1 or CYP2C6. 4'-Hydroxychalcone is a chalone derivative that exhibits moderate to good antiviral activity against tobacco mosaic virus (TMV). Synonyms: 2-Benzal-4'-hydroxyacetophenone; 2-Benzylidene-4'-hydroxyacetophenone; p-Cinnamoylphenol; NSC 242264; 4'-Hydroxychalcone. Grade: ≥98%. CAS No. 2657-25-2. Molecular formula: C15H12O2. Mole weight: 224.3.
4'-O-Methylbavachalcone
4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 20784-60-5. Molecular formula: C21H22O4. Mole weight: 338.4. Purity: 0.9985. Canonical SMILES: O=C(C1=CC(C/C=C(C)\C)=C(OC)C=C1O)/C=C/C2=CC=C(O)C=C2. Product ID: ACM20784605. Alfa Chemistry ISO 9001:2015 Certified. Categories: CHEBI:85123.
4'-O-Methylbroussochalcone B
4'-O-Methylbroussochalcone B is a natural chalcone found in the seeds of Psoralea corylifolia Linn. Synonyms: (2E)-1-[2-Hydroxy-4-methoxy-5-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 1-[2-hydroxy-4-methoxy-5-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (E)-; 2',4-Dihydroxy-4'-methoxy-5'-(3-methyl-2-butenyl)chalcone; 4'-O-Methylbavachalcone; O-Methylbroussochalcone B. Grade: >97%. CAS No. 20784-60-5. Molecular formula: C21H22O4. Mole weight: 338.40.
Bis (3, 4-methylenedioxy) chalcone
Bis (3, 4-methylenedioxy) chalcone. Group: Biochemicals. Alternative Names: 1,3-Bis(1,3-benzodioxol-5-yl)-2-propen-1-one. Grades: Highly Purified. CAS No. 76530-89-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C17H12O5. US Biological Life Sciences.
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Eriodictyol chalcone
Eriodictyol chalcone possesses both anti-aromatase and anti-17β-HSD activity. Synonyms: 2',3,4,4',6'-Pentahydroxychalcone; 3,4,2',4',6'-Pentahydroxychalcone. CAS No. 14917-41-0. Molecular formula: C15H12O6. Mole weight: 288.25.
Hesperidin methylchalcone
Hesperidin methylchalcone (Hesperidin methyl chalcone) is an orally active flavonoid that has analgesic, anti-inflammatory and antioxidant properties. Hesperidin methylchalcone exhibits vasoprotective activity. Hesperidin methylchalcone inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone can be used for the research of gout disease [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 24292-52-2. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-126382.
Hesperidin Methylchalcone
Hesperidin Methylchalcone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (e)-osyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl);2',3,4'-trihydroxy-4,6'-dimethoxy-chalcon4'-(6-o-(6-deoxy-alpha-l-mannopyr;2-propen-1-one,1-[4-[[6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyran;anosyl)-beta-d-glucopyranoside);(E)-3-(3-HYDROXY-4-METHOXY-PHENYL)-1-[2-HYDROXY-6-METHOXY-4-[(2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-((2R,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXYMETHYL)-TETRAHYDRO-PYRAN-2-YLOXY]-PHENYL]-PROPENONE;HESPERIDIN METHYL CHALCONE;Hesperidine Methyl Chalcone;1-[4-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-one. Appearance: Powder. CAS No. 24292-52-2. Molecular formula: C29H36O15. Mole weight: 624.59. Purity: 0.98. IUPACName: (E)-3-(3-hydroxy-4-methoxyphenyl)-1-[2-hydroxy-6-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxyphenyl]prop-2-en-1-one. Canonical SMILES: CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C(C(=C3)OC)C(=O)C=CC4=CC(=C(C=C4)OC)O)O)O)O)O)O)O)O. Density: 1.57 g/cm³. Product ID: ACM24292522. Alfa Chemistry ISO 9001:2015 Certified.
Licochalcone A is a chalconoid, a type of natural phenols. It can be isolated from root of Glycyrrhiza glabra (liquorice) or Glycyrrhiza inflata. It is a potent membrane-active agent that transforms normal erythrocytes into echinocytes. It exhibits potent antimalarial activity and might be developed into a new antimalarial drug. It had anti-tumor activity in all cell lines tested and enhanced the effect of paclitaxel and vinblastine chemotherapy. Synonyms: 4,4'-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone; 7-Dimethoxycoumarin; 3-Dimethylallyl-4,4'-dihydroxy-6-methoxychalcone; (E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one; (2E)-3-[5-(1,1-Dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-; 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (E)-. Grade: >98%. CAS No. 58749-22-7. Molecular formula: C21H22O4. Mole weight: 338.40.
Licochalcone B
Licochalcone B is extracted from the roots of Glycyrrhiza glabra L. It inhibits the adhesion,invasion and metastasis of human malignant bladder cancer T24 cells. It could significantly reduce the LPS-induced production of NO, TNFalpha and MCP-1. Synonyms: (2E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (E)-; (E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; 3,4,4'-Trihydroxy-2-methoxy-trans-chalcone; 3,4,4'-Trihydroxy-2-Methoxychalcone. Grade: >98%. CAS No. 58749-23-8. Molecular formula: C16H14O5. Mole weight: 286.28.
Metochalcone
Metochalcone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Megalip; Metochalcon; Trimepaton; Lesidrin; Spechol; 4,2,4-trimethoxy-chalcone; Chemicol; Solvocolo; Vesidril; Trimecolo; 2,4,4-trimethoxychalcone; 3,4,4-trimethoxychalcone; 2,4,4-trimethoxychalone; Metochalcone. Product Category: Heterocyclic Organic Compound. CAS No. 18493-30-6. Molecular formula: C18H18O4. Mole weight: 298.333120 [g/mol]. Purity: 0.96. IUPACName: 1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one. Density: 1.139g/cm³. Product ID: ACM18493306. Alfa Chemistry ISO 9001:2015 Certified.
Naringenin chalcone
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. Naringenin chalcone induces Apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 73692-50-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N3007.
Naringenin Chalcone
Formula: Group: Biochemicals. Grades: Plant Grade. CAS No. 73692-50-9. Pack Sizes: 20mg. US Biological Life Sciences.
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naringenin-chalcone synthase
In the presence of NADH and a reductase, 6'-deoxychalcone is produced. Group: Enzymes. Synonyms: chalcone synthase; flavanone synthase; 6'-deoxychalcone synthase; chalcone synthetase; DOCS; CHS. Enzyme Commission Number: EC 2.3.1.74. CAS No. 56803-04-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2254; naringenin-chalcone synthase; EC 2.3.1.74; 56803-04-4; chalcone synthase; flavanone synthase; 6'-deoxychalcone synthase; chalcone synthetase; DOCS; CHS. Cat No: EXWM-2254.
Neohesperidin dihydrochalcone
Neohesperidin dihydrochalcone is a synthetic glycoside chalcone, is added to various foods and beverages as a low caloric artificial sweetener. Uses: Scientific research. Group: Natural products. Alternative Names: Neohesperidin DC; NHDC. CAS No. 20702-77-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0154.
Pinocembrin chalcone
Pinocembrin chalcone is extracted from the rhizomes of Boesenbergia pandurata. It inhibits tyrosinase activity. It also inhibits the first step of enzymatic activation of heterocyclic amines and displays antimutagenic effect. It has antimicrobial activity against the antibiotic susceptible NG strain WHO V. It also shows activity against Candida albicans with a minimal inhibitory concentration value of 100 microg/mL. Synonyms: 2',4',6'-Trihydroxychalcone. Grade: 98.0%. CAS No. 4197-97-1. Molecular formula: C15H12O4. Mole weight: 256.25.
trans-Chalcone
trans-Chalcone. Group: Biochemicals. Grades: Highly Purified. CAS No. 614-47-1. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C15H12O. US Biological Life Sciences.
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trans-Chalcone
Trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity. Trans-Chalcone is a potent fatty acid synthase (FAS) and α-amylase inhibitor. Trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7. Synonyms: Chalcone; (E)-Chalcone; Benzalacetophenone; Benzylideneacetophenone; (2E)-1,3-diphenylprop-2-en-1-one. Grade: ≥97%. CAS No. 614-47-1. Molecular formula: C15H12O. Mole weight: 208.26.
trans-Chalcone
trans-Chalcone, isolated from Aronia melanocarpa skin, is a biphenolic core structure of flavonoids precursor. trans-Chalcone is a potent fatty acid synthase (FAS) and α-amylase inhibitor. trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7. trans-Chalcone has antifungal and anticancer activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 614-47-1. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-Y0598.
Trans-Chalcone
trans-Chalcone, isolated from Aronia melanocarpa skin, is a biphenolic core structure of flavonoids precursor. trans-Chalcone is a potent fatty acid synthase (FAS) and α-amylase inhibitor. trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7. trans-Chalcone has antifungal and anticancer activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Phenyltrans-styrylketone. Product Category: Inhibitors. Appearance: Pale yellow solid. CAS No. 614-47-1. Molecular formula: C15H12O. Mole weight: 208.26. Purity: 0.95. IUPACName: (E)-1,3-Diphenylprop-2-en-1-one. Canonical SMILES: C1=CC=C(C=C1)C=CC(=O)C2=CC=CC=C2. Density: 1.0712 g/cm³. ECNumber: 210-383-8. Product ID: ACM614471. Alfa Chemistry ISO 9001:2015 Certified.
trans-Chalcone-[d12]
trans-Chalcone-[d12]. Synonyms: benzylideneacetophenone-d12. Grade: 98% atom D. CAS No. 307496-21-5. Molecular formula: C15D12O. Mole weight: 220.33.
trans-Chalcone-d12,98 atom % d
trans-Chalcone-d12,98 atom % d. Uses: Designed for use in research and industrial production. Additional or Alternative Names: trans-Chalcone-d12, benzylideneacetophenone-d12, 517879_ALDRICH, 307496-21-5. Product Category: Heterocyclic Organic Compound. CAS No. 307496-21-5. Molecular formula: C15H11DO. Mole weight: 209.2613418. Purity: 0.96. IUPACName: (E)-2,3-dideuterio-1,3-bis(2,3,4,5,6-pentadeuteriophenyl)prop-2-en-1-one. Canonical SMILES: C1=CC=C(C=C1)C=CC(=O)C2=CC=CC=C2. Product ID: ACM307496215. Alfa Chemistry ISO 9001:2015 Certified.
[1,1'-Bis(di-tert-butylphosphino)ferrocene]palladium(II) Dichloride. Uses: 1,1'-bis (di-t-butylphosphino)ferrocene palladium dichloride is used as a catalyst for the preparation of chalcones. Additional or Alternative Names: PdCl2(dtbpf). Product Category: Palladium series catalysts. Appearance: dark red crystals. CAS No. 95408-45-0. Molecular formula: C26H44Cl2FeP2Pd. Mole weight: 651.75. Purity: Pd ≥16.3%. IUPACName: Dichloro[1,1-Bis(di-Tert-Butylphosphino)Ferrocene]Palladium(II). Product ID: ACM95408450. Alfa Chemistry ISO 9001:2015 Certified. Categories: 664-483-5.
1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one is a chalcone compound used as a selective inhibitor of breast cancer resistance protein. Group: Biochemicals. Grades: Highly Purified. CAS No. 53350-27-9. Pack Sizes: 25mg, 50mg. Molecular Formula: C20H22O7. US Biological Life Sciences.
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1-Bromo-3-methyl-2-butene (90%)
1-Bromo-3-methyl-2-butene is used to prepare xanthine dipeptidyl peptidase inhibitors for treatment of type 2 diabetes. It can also be used to synthesize natural and non-natural prenylated chalcones with antitumor, antioxidant activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 870-63-3. Pack Sizes: 1g, 5g. Molecular Formula: C5H9Br, Molecular Weight: 149.03. US Biological Life Sciences.
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1-Phenyl-2-buten-1-one
1-Phenyl-2-buten-1-one is used in the preparation of chalcones derivatives and analogs and for the testing of their antimicrobial activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 495-41-0. Pack Sizes: 500mg, 1g. Molecular Formula: C10H10O, Molecular Weight: 146.19. US Biological Life Sciences.
2,2'-[1,3-Phenylenebis(4,5-dihydro-1H-pyrazole-5,3-diyl)]bis-phenol is used in the synthetic preparation of bis(pyrazolines) by cyclization of bis(chalcones) with hydrazine. Group: Biochemicals. Grades: Highly Purified. CAS No. 528599-50-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C24H22N4O2, Molecular Weight: 398.46. US Biological Life Sciences.
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2,4-Dihydroxy-6-methoxyacetophenone
2,4-Dihydroxy-6-methoxyacetophenone is a reagent that is used in the preparation of polysubstituted synthetic chalcones. Group: Biochemicals. Grades: Highly Purified. CAS No. 3602-54-8. Pack Sizes: 250mg, 2.5g. Molecular Formula: C9H10O4, Molecular Weight: 182.17. US Biological Life Sciences.
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2,4-Dihydroxy-6-methoxyacetophenone-d3
2,4-Dihydroxy-6-methoxyacetophenone-d3 is the isotope labelled analog of 2,4-Dihydroxy-6-methoxyacetophenone. 2,4-Dihydroxy-6-methoxyacetophenone is a reagent that is used in the preparation of polysubstituted synthetic chalcones. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C9H7D3O4, Molecular Weight: 185.19. US Biological Life Sciences.
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2-Acetylthiophene
2-Acetylthiophene is used in the synthesis of organoboranes as well as chalcone derivatives as anti-inflammatories. Group: Biochemicals. Alternative Names: 1-(2-Thienyl)ethanone; 1-(2-Thienyl)-1-ethanone; 1-(2-Thienyl)ethanone; 1-(Thiophen-2-yl)ethanone; 2-Acetothienone; 2-Acetothiophene; 2-Acetylthiophene; 2-Thienyl methyl ketone; Methyl 2-thienyl ketone; NSC 2345; α-Acetylthiophene. Grades: Highly Purified. CAS No. 88-15-3. Pack Sizes: 25g. US Biological Life Sciences.
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2-Acetylthiophene
2-Acetylthiophene is used in the synthesis of organoboranes as well as chalcone derivatives as anti-inflammatories. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Methyl 2-thienyl ketone. Product Category: Thiophenes. Appearance: Yellow to brown liquid. CAS No. 88-15-3. Molecular formula: C6H6OS. Mole weight: 126.18. Density: 1.16. ECNumber: 201-804-6. Product ID: ACM88153. Alfa Chemistry ISO 9001:2015 Certified.
(2E)-1-(2-Hydroxyphenyl)-3-phenyl-2-propen-1-one
A synthetic chalcone with antibacterial and potential antitumoral activity. Group: Biochemicals. Alternative Names: (E)-2'-Hydroxy-chalcone; (E)-o-Hydroxyphenyl Styryl Ketone; NSC 170284; trans-2'-Hydroxychalcone. Grades: Highly Purified. CAS No. 888-12-0. Pack Sizes: 2.5g. US Biological Life Sciences.
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2-Naphthalene carboxaldehyde
2-Naphthalene carboxaldehyde is used to prepare chalcone analogs with increased antileishmanial activities. It is also used to synthesize (aryl) (oxo) spiro[cyclopropane-1, 3'-indole] derivatives with their activities as HIV-1 non-nucleoside reverse transcriptase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 66-99-9. Pack Sizes: 5g, 25g. Molecular Formula: C11H8O. US Biological Life Sciences.
Worldwide
2-Propen-1-one,3-(4-methoxyphenyl)-1-phenyl-
2-Propen-1-one,3-(4-methoxyphenyl)-1-phenyl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Methoxychalcone, Anisalacetophenone, Chalcone, 4-methoxy-, p-Methoxyphenyl styryl ketone, Phenyl p-methoxystyryl ketone, 4-Methoxybenzylideneacetophenone, CCRIS 2230, Chalcone, 4-methoxy- (8CI), EINECS 213-499-7, NSC 11866, CID94197, NSC11866, AI3-17319, 3-(4-Methoxyphenyl)-1-phenyl-2-propen-1-one, LS-188219, 2-Propen-1-one, 3-(4-methoxyphenyl)-1-phenyl-, 2-Propen-1-one, 3-(4-methoxyphenyl)-1-phenyl- (9CI), 959-33-1. Product Category: Heterocyclic Organic Compound. Appearance: yellow Crystals. CAS No. 959-33-1. Molecular formula: C16H14O2. Mole weight: 238.28. Purity: >98.0%(GC). IUPACName: 3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one. Canonical SMILES: COC1=CC=C(C=C1)C=CC(=O)C2=CC=CC=C2. Density: 1.114 g/cm³. ECNumber: 213-499-7. Product ID: ACM959331. Alfa Chemistry ISO 9001:2015 Certified.
2-Sulfobenzaldehyde Hydrate
2-Sulfobenzaldehyde, is used for the synthesis of a series of novel 3-[N, N-bis(2-hydroxyethyl)-amino]-chalcone derivatives, having antimicrobial activity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g, 10g. Molecular Formula: C7H6O4S; xH2O. US Biological Life Sciences.
Worldwide
3,4-Dimethoxybenzaldehyde
3,4-Dimethoxybenzaldehyde. Synonyms: Methylvanillin, NSC 24521, NSC 8500, Vanillin methyl ether, Veratraldehyde. CAS No. 120-14-9. Pack Sizes: 5, 100, 500 g in poly bottle. Product ID: CDC10-0173. Molecular formula: (CH3O)2C6H3CHO. Category: Flavoring Chemical Agents. Product Keywords: Cosmetic Ingredients; Flavoring Chemical Agents; 3,4-Dimethoxybenzaldehyde; CDC10-0173; 120-14-9; (CH3O)2C6H3CHO; Methylvanillin, NSC 24521, NSC 8500, Vanillin methyl ether, Veratraldehyde; 204-373-2; MFCD00003363; 120-14-9. Purity: 0.99. Color: White to yellow. EC Number: 204-373-2. Physical State: Solid. Solubility: alcohol: freely soluble. Quality Level: 100. Storage: 2-8°C. Application: 3,4-Dimethoxybenzaldehyde was used in the preparation of 4-chloromethyl-2-(dimethoxyphenyl)-1,3-dioxolane. It was used in the synthesis of (+)-lithospermic acid, having anti-HIV activity. Boiling Point: 281 °C (lit.). Melting Point: 40-43 °C (lit.). Density: 1.1708 (rough estimate). Product Description: 3,4-Dimethoxybenzaldehyde forms 1:1 inclusion complexes with cyclodextrins. It reacts with 3-acetyl-2,5-dimethythiophene to yield chalcone dye, (2E)-3-(3,4-Dimethoxyphenyl)-1-(2,5-dimethylthiophen-3-yl)prop-2-en-1-one.
3-Acetyl-5-chloro-2-thiophenesulfonamide
3-Acetyl-5-chloro-2-thiophenesulfonamide is a reactant used in the preparation of heteroaryl chalcones as potent antimicrobial agents and Brinzolamide (B677600), a topical carbonic anhydrase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 160982-10-5. Pack Sizes: 250mg. US Biological Life Sciences.
3-Chloro-N-(1-methylethyl)-benzenemethanamine-d7 Hydrochloride is derived from 3-Chlorobenzaldehyde (C364495), which is a chemical reagent used in synthesis of y-butyrolactones. Also, used in the synthesis of chalcones and flavonoids with inhibitory activity toward Tuberculosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H7D7ClN HCl, Molecular Weight: 190.723646. US Biological Life Sciences.
Worldwide
3'-Hydroxyacetophenone
An impurity of Etilefrin. Etilefrin is a sympathomimetic drug that increases the pulse rate, cardiac output, stroke volume, central venous pressure and mean arterial pressure of healthy individuals. Uses: 3'-hydroxyacetophenone is a chemical reagent used in the synthesis and preparation of chalcones and flavonoids as anti-tuberculosis agents, as well as antileishmanial chaocones. Synonyms: 1-(3-hydroxyphenyl)ethanone. Grade: > 95 %. CAS No. 121-71-1. Molecular formula: C8H8O2. Mole weight: 136.15.
3-Hydroxyacetophenone
3-Hydroxyacetophenone is a chemical reagent used in the synthesis and preparation of chalcones and flavonoids as anti-tuberculosis agents, as well as antileishmanial chaocones. Group: Biochemicals. Alternative Names: 1- (3-Hydroxyphenyl) ethanone; 3'-Hydroxyacetophenone; 1- (3-Hydroxyphenyl) ethanone; 3-Acetylphenol; 3-Hydroxyphenylethanone; 3'-Hydroxyacetophenone; A 0104; NSC 2440; m-Acetylphenol; m-Hydroxyacetophenone. Grades: Highly Purified. CAS No. 121-71-1. Pack Sizes: 25g. US Biological Life Sciences.
Worldwide
6-Methoxy-1-tetralone
6-Methoxy-1-tetralone is a reagent useful in the synthesis of (2-(furanyl)vinyl)-1-tetralone chalcones which possesses anticancer agents and inducers of apoptosis. Group: Biochemicals. Alternative Names: 3,4-Dihydro-6-methoxy-1(2H)-naphthalenone; 1,2,3,4-Tetrahydro-6-methoxy-1-naphthalenone; 1-Oxo-1,2,3,4-tetrahydro-6-methoxynaphthalene; 6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-one; 6-Methoxy-1-oxo-1,2,3,4-tetrahydronaphthalene; 6-Methoxy-3,4-dihydro-1(2H)-naphthalenone; 6-Methoxy-3,4-dihydro-2H-naphthalen-1-one; 6-Methoxy-3,4-dihydronaphthalene-1(2H)-one; 6-Methoxy-α-tetralone; NSC 41700. Grades: Highly Purified. CAS No. 1078-19-9. Pack Sizes: 50g, 100g, 250g, 500g. Molecular Formula: C??H??O?, Molecular Weight: 176.21. US Biological Life Sciences.
Worldwide
acridone synthase
Belongs to a superfamily of plant polyketide synthases. Has many similarities to chalcone and stilbene synthases (see reaction synthesis). Group: Enzymes. Enzyme Commission Number: EC 2.3.1.159. CAS No. 99085-53-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2098; acridone synthase; EC 2.3.1.159; 99085-53-7. Cat No: EXWM-2098.
Butein
Butein is a cAMP-specific PDE inhibitor with an IC 50 of 10.4 μM for PDE4 [1]. Butein is a specific protein tyrosine kinase inhibitor with IC 50 s of 16 and 65 μM for EGFR and p60 c-src in HepG2 cells [2]. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a [3]. Butein is a SIRT1 activator (STAC). Uses: Scientific research. Group: Natural products. Alternative Names: 2,3,4,4-tetrahydroxy Chalcone. CAS No. 487-52-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16558.
Cardamonin
Cardamonin can be found from cardamom, and can target various signaling molecules, transcriptional factors, cytokines and enzymes. Cardamonin can inhibit mTOR , NF-κB , Akt , STAT3 , Wnt/β-catenin and COX-2. Cardamonin shows anticancer, anti-inflammatory, antimicrobial and antidiabetic activities [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cardamomin; Alpinetin chalcone. CAS No. 18956-16-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0279.
Diethyl Bromomalonate
Diethyl Bromomalonate is a chemical constituent of the asymmetric cyclopropanation of chalcones. Also used in the preparation of nanaplatforms for NIR imaging-guided photodynamic therapy of cancer cells. Group: Biochemicals. Alternative Names: Bromomalonic Acid Diethyl Ester; 2-Bromomalonic Acid Diethyl Ester; Diethyl 2-bromo-1,3-propanedioate; Diethyl 2-Bromomalonate; Diethyl 2-bromopropanedioate; Diethyl Bromomalonate; Diethyl α-Bromomalonate; Ethyl Bromomalonate; NSC 1985; α-Bromomalonic Ester. Grades: Highly Purified. CAS No. 685-87-0. Pack Sizes: 50g. US Biological Life Sciences.
Worldwide
Flavokawain A
Flavokawain A, a proming anticarcinogenic agent , is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer [1]. Uses: Scientific research. Group: Natural products. CAS No. 3420-72-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N2420.
Flavokawain B
Flavokawain B (Flavokavain B) is an orally active chalcone. Flavokawain B results in activation of caspase-9, -3 and -8 , cleavage of PARP. Flavokawain B down-regulates Bcl-2 with concomitant increase in Bax level. Flavokawain B inhibits NF-κB , PI3K/Akt and MAPK signaling pathway. Flavokawain B exhibits Apoptotic effects. Flavokawain B inhibits MMP-9 and promotes ROS generation. Flavokawain B inhibits multiple tumors and inflammation [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] [13]. Uses: Scientific research. Group: Natural products. Alternative Names: Flavokavain B. CAS No. 1775-97-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2132.
Glabralide A
Glabralide A is a kind of a unique skeleton of the chalcone-coupled monoterpenoid. It has a bicyclo [2.2.2] octene core unit with five chiral centers. Synonyms: Glabralide A; 1969289-10-8; B0005-267493. Grade: 97.0%. CAS No. 1969289-10-8. Molecular formula: C27H32O5. Mole weight: 436.00.
Helichrysetin
Helichrysetin is a natural chalcone isolated from the fruits of Alpinia katsumadai Hayata, it exhibits the activity of anticancer and has mild anti-HIV-1 PR activity. Uses: Anticancer. Synonyms: (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-2-prop en-1-one. Grade: >98%. CAS No. 62014-87-3. Molecular formula: C16H14O5. Mole weight: 286.3.
Homobutein
Homobutein a natural chalcones (can be found in many medicinal plants, fruits, vegetables, spices and nuts), is a potent HDACs/NF-κB dual inhibitor with IC50s of 190 and 38 μM, respectively. Homobutein also a chelator of iron (II and III) cations, shows various activities, including anticancer, anti-inflammatory, antiparasite and antioxidation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2',4,4'-TRIHYDROXY-3-METHOXY CHALCONE;3-METHOXY-2',4',4-TRIHYDROXYCHALCONE;HOMOBUTEIN;(E)-2',4,4'-trihydroxy-3-methoxychalcone;3-O-methylbutein;HOMOBUTEIN WITH HPLC;HOMOBUTEIN hplc;(E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-one. Product Category: Inhibitors. Appearance: Powder. CAS No. 34000-39-0. Molecular formula: C16H14O5. Mole weight: 286.3. Purity: 0.98. IUPACName: (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one. Canonical SMILES: COC1=C(C=CC(=C1)C=CC(=O)C2=C(C=C(C=C2)O)O)O. Density: 1.369 g/cm³. ECNumber: 251-782-7. Product ID: ACM34000390. Alfa Chemistry ISO 9001:2015 Certified.
Isoliquiritigenin
Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2',4,4'-Trihydroxy-trans-chalcone. Product Category: Inhibitors. Appearance: Yellow to orange powder. CAS No. 961-29-5. Molecular formula: C15H12O4. Mole weight: 256.25. Purity: 0.98. IUPACName: (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one. Canonical SMILES: C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O. Density: 1.384±0.06 g/cm³. Product ID: ACM961295. Alfa Chemistry ISO 9001:2015 Certified.
isoliquiritigenin 2'-O-methyltransferase
Not identical to EC 2.1.1.65, licodione 2'-O-methyltransferase. While EC 2.1.1.154, isoliquiritigenin 2'-O-methyltransferase can use licodione as a substrate, EC 2.1.1.65 cannot use isoliquiritigenin as a substrate. Group: Enzymes. Synonyms: chalcone OMT; CHMT. Enzyme Commission Number: EC 2.1.1.154. CAS No. 139317-14-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1750; isoliquiritigenin 2'-O-methyltransferase; EC 2.1.1.154; 139317-14-9; chalcone OMT; CHMT. Cat No: EXWM-1750.
Loureirin A
Loureirin A is a chalcone extracted from the red resin of the herbs of Dracaena cochinchinensis, which is known as Dragon's Blood. It is a part of traditional Chinese medicine which helps combat neurodegenerative diseases. It inhibits platelet activation by an impairment of PI3K/Akt signaling. It also could inhibit Akt phosphorylation. It negatively affects agonist-induced platelet aggregation such as ADP, collagen, thrombin and collagen-related peptide (CRP). It promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound by activating Wnt/-catenin pathway. Synonyms: 3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone. Grade: 98.5%. CAS No. 119425-89-7. Molecular formula: C17H18O4. Mole weight: 286.32.
phloroisovalerophenone synthase
Closely related to EC 2.3.1.74, naringenin-chalcone synthase. The product, 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one, is phloroisovalerophenone. Also acts on isobutyryl-CoA as substrate to give phlorisobutyrophenone. The products are intermediates in the biosynthesis of the bitter (α) acids in hops (Humulus lupulus). Group: Enzymes. Synonyms: valerophenone synthase; 3-methyl-1-(trihydroxyphenyl)butan-1-one synthase. Enzyme Commission Number: EC 2.3.1.156. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2095; phloroisovalerophenone synthase; EC 2.3.1.156; valerophenone synthase; 3-methyl-1-(trihydroxyphenyl)butan-1-one synthase. Cat No: EXWM-2095.
pinosylvin synthase
Not identical with EC 2.3.1.74 (naringenin-chalcone synthase) or EC 2.3.1.95 (trihydroxystilbene synthase). Group: Enzymes. Synonyms: stilbene synthase (ambiguous); pine stilbene synthase (ambiguous). Enzyme Commission Number: EC 2.3.1.146. CAS No. 72994-49-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2085; pinosylvin synthase; EC 2.3.1.146; 72994-49-1; stilbene synthase (ambiguous); pine stilbene synthase (ambiguous). Cat No: EXWM-2085.
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