Chloro Hydroxy Pyrimidine Suppliers USA
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Product | Description | |
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5-Chloro-2-hydroxy-pyrimidine Quick inquiry Where to buy Suppliers range | 5-Chloro-2-hydroxy-pyrimidine (CAS# 54326-16-8) is used to prepare dimethoxy-pyrrolidylquinazolines as brain penetrable PDE10A inhibitors. It is also used in the synthesis of platinum(II) hydroxypyrimidinato ethylenediamine tetranuclear metallacalix[4]arene complexes. Synonyms: 5-Chloropyrimidin-2-ol. Grades: ≥ 98 %. CAS No. 54326-16-8. Molecular formula: C4H3ClN2O. Mole weight: 130.53. | |
5-Chloro-2-hydroxy-pyrimidine 99+% (HPLC) Quick inquiry Where to buy Suppliers range | 5-Chloro-2-hydroxy-pyrimidine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
5-Chloro-4-hydroxy-6-difluoro methyl pyrimidine Quick inquiry Where to buy Suppliers range | 5 Chloro 4 hydroxy 6 difluoro methyl pyrimidine. CAS No. 425394-28-1. | |
5-Chloro-4-hydroxy-6-trifluoromethyl-pyrimidine Quick inquiry Where to buy Suppliers range | 126538-83-8, 5-CHLORO-4-HYDROXY-6-TRIFLUOROMETHYL-PYRIMIDINE, 5-Chloro-6-trifluoromethyl-pyrimidin-4-ol, 5-chloro-4-(trifluoromethyl)-1H-pyrimidin-6-one, 5-Chloro-4-hydroxy-6-(trifluoromethyl)pyrimidine, 5-chloro-6-(trifluoromethyl)pyrimidin-4(3H)-one, SCHEMBL6715914, SCHEMBL8507623, 5-CHLORO-6-(TRIFLUOROMETHYL)-1H-PYRIMIDIN-4-ONE, DTXSID90476614, BFA53883, MFCD09909761, AKOS006314304, AKOS023113538, AB54868, GS-1945, C90390, 5-chloro-6-(trifluoromethyl)-1,4-dihydropyrimidin-4-one, 5-chloro-6-(trifluoromethyl)-3,4-dihydropyrimidin-4-one. | |
Mirk/Dyrk1B Inhibitor, Compound A (N- (2-Chloro-5- (3-chlorobenzylcarbamoyl) phenyl) -2-methoxy-7-oxo-7, 8-dihydropyrido[2, 3-d]pyrimidine-6-carboxamide, N- (2-Chloro-5- ( (3-chlorobenzyl) carbamoyl) phenyl) -7-hydroxy-2-methoxypyrido[2, 3-d]pyrimidine-6-carboxamide) Quick inquiry Where to buy Suppliers range | A cell-permeable di hydropyridopyrimidine-carboxamide compound that acts as a potent and reversible inhibitor of Mirk/Dyrk1B and Dyrk1A kinases (IC50 = 68 and 22nM). Exhibits very high selectivity for Mirk/Dyrk1B compared to Abl, Flt3, and MARK1 (64, 56 and 73% inhibition at 10uM, respectively) and a panel of 46 other kinases. Shown to induce activation of caspase-3 and sensitize tumor cells to the action of gemcitabine and cisplatin, possibly by de-stabilizing p27. Preferentially increases cycling in Mirk-elevated quiescent pancreatic cancer cells (SU86.86, Panc1, AsPc1, and SW620 at ~1uM). Also, shown to increase level of superoxides in quiescent pancreatic tumor cells (Panc1, SU86.86, and AsPc1) by blocking SOD2 and SOD3 activities. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
5-Chloro-4-hydroxy-2-methyl-6-trifluoromethyl-pyrimidine Quick inquiry Where to buy Suppliers range | 425394-36-1, 5-CHLORO-2-METHYL-6-(TRIFLUOROMETHYL)PYRIMIDIN-4-OL, 5-CHLORO-4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYL-PYRIMIDINE, SCHEMBL6727288, AB54877, C90477. | |
1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine Quick inquiry Where to buy Suppliers range | 1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine is an antineoplastic biomolecule used in cancer research. It's an analog of the nucleoside cytosine, inhibiting DNA synthesis to stop tumor cells replication. Synonyms: 2(1H)-Pyrimidinone, 4-amino-1-(2-chloro-2-deoxy-beta-D-arabinofuranosyl)-; 4-Amino-1-(2-chloro-2-deoxy-.beta.-D-arabinofuranosyl)pyrimidin-2(1H)-one; 4-amino-1-[(2R,3S,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one. CAS No. 58461-30-6. Molecular formula: C9H12ClN3O4. Mole weight: 261.66. | |
1-(2'-Deoxy-2'-chloro-b-L-arabinofuranosyl)-thymine Quick inquiry Where to buy Suppliers range | 1-(2'-Deoxy-2'-chloro-b-L-arabinofuranosyl)-thymine, also known as 2'-C-C-AraT, is a nucleoside analog utilized in biomedical research particularly in antiviral and anticancer therapy studies. It has demonstrated inhibitory effects against Hepatitis B viral replication. Synonyms: 1-(2'-Deoxy-2'-chloro-β-L-arabinofuranosyl)-thymine; 1-[(2S,3R,4S,5S)-3-chloro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 1-(2-Chloro-2-deoxy-β-L-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione. Molecular formula: C10H13ClN2O5. Mole weight: 276.67. | |
1-Benzyl-2-chloro-1H-indole-3-carboxaldehyde Quick inquiry Where to buy Suppliers range | 1-Benzyl-2-chloro-1H-indole-3-carboxaldehyde is an intermediate in synthesizing 2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol (T294270), a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. CAS No. 77655-46-0. Pack Sizes: 500mg, 1g. Molecular Formula: C16H12ClNO. US Biological Life Sciences. | Worldwide |
2'-Chloro-2'-deoxycytidine Quick inquiry Where to buy Suppliers range | 2'-Chloro-2'-deoxycytidine is a nucleoside analogue, orchestrating its antineoplastic prowess via impeding DNA synthesis and evoking apoptosis exclusively within malignant cells. Synonyms: 2'-Deoxy-2'-chloro-cytidine; 4-Amino-1-((2R,3R,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 10212-19-8. Molecular formula: C9H12ClN3O4. Mole weight: 261.66. | |
2'-Chloro-2'-deoxyuridine Quick inquiry Where to buy Suppliers range | 2'-Chloro-2'-deoxyuridine (CAS# 4753-04-2 ) is a useful research chemical. Synonyms: 2'-Deoxy-2'-chlorouridine; 1-((2R,3R,4R,5R)-3-Chloro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥ 95 %. CAS No. 4753-4-2. Molecular formula: C9H11ClN2O5. Mole weight: 262.65. | |
2'-Deoxy-2'-fluoro-L-uridine Quick inquiry Where to buy Suppliers range | White to off-white solid. Group: Main Products. Alternative Names: (S)-2-chloro-butyric acid dimethylamide; L-2-Chlor-N,N-dimethyl-butyramid; L-2-deoxy-2-fluorouridine; (S)-2-Chlor-buttersaeure-dimethylamid; 2-Chloro-N,N-dimethylbutyramide; Butanamide,2-chloro-N,N-dimethyl; 2-fluoro-L-uridine. Grades: 96%. CAS No. 622785-69-7. Molecular formula: C9H11FN2O5. Mole weight: 246.20. IUPAC Name: 1-[(2R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione. Exact Mass: 246.06500. SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)F. InChIKey: UIYWFOZZIZEEKJ-AYZDMWBASA-N. | |
3-?[2-?Chloro-?1-?(phenylmethyl)?-?1H-?indol-?3-?yl]?-?2-?cyano-?2-?propenoic Acid Quick inquiry Where to buy Suppliers range | 3-?[2-?Chloro-?1-?(phenylmethyl)?-?1H-?indol-?3-?yl]?-?2-?cyano-?2-?propenoic Acid is an intermediate in synthesizing 2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol (T294270), a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. CAS No. 188034-08-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C21H17ClN2O2. US Biological Life Sciences. | Worldwide |
3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one(paliperidone) Quick inquiry Where to buy Suppliers range | 3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one(paliperidone). Group: Heterocyclic Organic Compound. Alternative Names: 3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone). CAS No. 260273-82-3. Molecular formula: C11H11ClN2O2. Mole weight: 238.673. | |
3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Quick inquiry Where to buy Suppliers range | 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one. Group: Heterocyclic Organic Compound. Alternative Names: 3-(2-CHLOROETHYL)-9-HYDROXY-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE;3-(2-Chloroethyl)-2-methyl-9-hydroxy-6,7,8,9-tetrahydro-4H-pyrido [1,2-a] pyrimidin-4-one;3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one;3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-α]pyrimidin-4-one;3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidine-4-one;3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-one ,98%;Paliperidone Intermediate 1;3-(2-chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one. CAS No. 130049-82-0. Molecular formula: C11H15ClN2O2. Mole weight: 242.7. Melting Point: 100-102°C. | |
3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Quick inquiry Where to buy Suppliers range | 3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
3-(2-Chloroethyl)-9-hydroxy-2-methyl-4H-Pyrido[1,2-a]pyrimidin-4-one Hydrochloride Quick inquiry Where to buy Suppliers range | 3-(2-Chloroethyl)-9-hydroxy-2-methyl-4H-Pyrido[1,2-a]pyrimidin-4-one Hydrochloride is an intermediate in the synthesis of analog of Paliperidone (P141000), a combined serotonin and dopamine receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 849727-62-4. Pack Sizes: 25mg, 250mg. Molecular Formula: C11H12Cl2N2O2. US Biological Life Sciences. | Worldwide |
4-Chloro-6-ethoxy-2-pyrimidinamine Quick inquiry Where to buy Suppliers range | 89784-02-1, 4-CHLORO-6-ETHOXY-2-PYRIMIDINAMINE, 4-chloro-6-ethoxypyrimidin-2-amine, 2-AMINO-4-CHLORO-6-ETHOXYPYRIMIDINE, SCHEMBL1576783, DTXSID70396684, 4-Chloro-6-ethoxypyrimidine-2-amine, MFCD00457060, STK370877, 2-amino-4-chloro-6-ethoxy-pyrimidine, AKOS005445680, 2-HYDROXY-3-BROMO-4-PICOLINE, AS-9343, CCG-321698, SB56476, CS-0312809, FT-0647325. | |
5-Amino-2-chlorophenol Quick inquiry Where to buy Suppliers range | 5-Amino-2-chlorophenol is used in the synthesis of antimalarial quinolones. Also used in the synthesis of potent anti-HIV agents based upon pyrimidinylphenylamine 1. Group: Biochemicals. Alternative Names: 2-Chloro-5-aminophenol; 3-Amino-6-chlorophenol; 3-Hydroxy-4-chloroaniline; 5-Amino-2-chlorophenol. Grades: Highly Purified. CAS No. 6358-6-1. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
5-Chloro-2,4-difluoro-6-methylpyrimidine Quick inquiry Where to buy Suppliers range | 5-chloro-2,4-difluoro-6-methylpyrimidine, 72630-78-5, 5-Chloro-2,4-difluoro-6-methyl-pyrimidine, Pyrimidine,5-chloro-2,4-difluoro-6-methyl-, SCHEMBL8947552, DTXSID30515576, 1-Boc-4-Hydroxy-L-prolineethylester, MFCD00036058, AKOS006345917, SB55922, CS-0455295, FT-0664626, A837582, 5-chloranyl-2,4-bis(fluoranyl)-6-methyl-pyrimidine, W-203641, 5-chloro-2,4-difluoro-6-methyl-pyrimidine, AldrichCPR. | |
5-Chloro-2'-deoxyuridine Quick inquiry Where to buy Suppliers range | It is an anticancer agent and a radio-sensitizing agent for cancer treatment. Synonyms: 2'-Deoxy-5-chlorouridine; 5-Chlorodeoxyuridine; Chlorodeoxyuridine; NSC 749426; 5-chloro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 50-90-8. Molecular formula: C9H11ClN2O5. Mole weight: 262.65. | |
5-Chloro-4-hydroxy-6-isopropylpyrimidine Quick inquiry Where to buy Suppliers range | 5-CHLORO-4-HYDROXY-6-ISOPROPYLPYRIMIDINE, 162328-48-5, 5-Chloro-6-(propan-2-yl)pyrimidin-4(1H)-one, SCHEMBL6718492, DTXSID80570332, AKOS006314612, AB54889, 5-chloro-4-propan-2-yl-1H-pyrimidin-6-one, 5-chloro-6-propan-2-yl-1H-pyrimidin-4-one, 5-CHLORO-6-(PROPAN-2-YL)PYRIMIDIN-4-OL. | |
5-Chloro-6-methylpyrimidin-4-ol Quick inquiry Where to buy Suppliers range | 7752-72-9, 5-Chloro-6-methylpyrimidin-4(3H)-one, 5-CHLORO-6-METHYLPYRIMIDIN-4(1H)-ONE, 5-chloro-6-methylpyrimidin-4-ol, 5-chloro-6-methyl-1H-pyrimidin-4-one, 5-chloro-4-methyl-1H-pyrimidin-6-one, 5-CHLORO-4-HYDROXY-6-METHYLPYRIMIDINE, 5-chloro-6-methyl-1,4-dihydropyrimidin-4-one, CHEMBL472375, SCHEMBL6719975, DTXSID20343300, 5-Chloro-6-methyl-4-pyrimidinol #, MFCD00234070, AKOS006348463, AKOS015892531, AKOS027470106, Pyrimidin-4-ol, 5-chloro-6-methyl-, 5-Chloro-6-hydroxy-4-methylpyrimidine, AB05118, GS-6324, 4-hydroxyl-5-chloro-6-methylpyrimidine, 5-Chloro-6-methylpyrimidine-4(3H)-one, CS-0045765, FT-0746551, 5-chloro-6-methyl-3,4-dihydropyrimidin-4-one, H10076, A839126, J-517377. | |
6-AMINO-4-CHLORO-1,2-DIHYDRO-1-HYDROXY-2-IMINOPYRIMIDINE Quick inquiry Where to buy Suppliers range | 2,6-Diamino-4-chloropyrimidine 1-oxide, 35139-67-4, 34960-71-9, 6-chloro-3-hydroxy-2-iminopyrimidin-4-amine, 6-AMINO-4-CHLORO-1,2-DIHYDRO-1-HYDROXY-2-IMINOPYRIMIDINE, 6-Amino-4-chloro-2-iminopyrimidin-1(2H)-ol, 6-chloropyrimidine-2,4-diamine 3-oxide, NSC-137211, 2,6-Diamino-4-chloropyrimidine-1-oxide, 6-Chloro-pyrimidine-2,4-diamine 3-Oxide, 2,4-Pyrimidinediamine, 6-chloro-, 3-oxide, Minoxidil Impurity A, 6-chloro-3-oxidopyrimidin-3-ium-2,4-diamine, 2,6-Diamino-4-chloropyrimidine1-oxide, BY7Z5QM433, SCHEMBL2292431, SCHEMBL9621590, DTXSID801204863, AMY25267, BCP31046, Minoxidil impurity A [EP impurity], MFCD00134274, NSC137211, STK525297, AKOS005458824, AKOS006229264, 2,4-diamino-6-chloropyrimidine 3-oxide, 2,4-diamino-6-chloropyrimidine-3-oxide, 2,4-diamino-6-chloro-pyrimidine-3-oxide, FT-0639231, FT-0661669, 2,6-Diamino-4-chloropyrimidine 1-oxide, 98%, N10804, 6-amino-4-chloro-1,2-dihydro-2-imino-1-pyrimidinol, 6-amino-4-chloro-2-imino-1,2-dihydropyrimidin-1-ol, 6-amino-1,2-dihydro-1-hydroxy-2-imino-4-chloropyrimidine, 6-amino-4-chloro-1,2-dihydro-1-hydroxy-2-imino pyrimidine, 6-Chloro-2,3-dihydro-3-hydroxy-2-imino-4-pyrimidinamine, 2,6-Diamino-4-chloropyrimidine 1-oxide; Minoxidil EP Impurity A pound>>6-Chloro-pyrimidine-2,4-diamine 3-Oxide. | |
ALS-8176 (active form) Quick inquiry Where to buy Suppliers range | ALS-8176 (active form), a 4'-substituted cytidine analogue, is a potent, selective RSV polymerase inhibitor. It has an EC50 of 0.15 μM in the RSV replicon assay and an IC50= 0.02 μM due to its corresponding 5'-triphosphate in the RSV polymerase assay. Synonyms: 4-amino-1-[(2R,3R,4R,5R)-5-(chloromethyl)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-oneALS-8176 (active form); ALS-8112; ALS8112; ALS 8112. UNII-7795987MKM7795987MKMCHEMBL3417243SCH EMBL15070479CS-5472; HY-12983; CS 5472; HY 12983; CS5472; HY129834'-Chloromethyl-2'-deoxy-2'-fluorocytidineCytidine. Grades: 99.67%. CAS No. 1445379-92-9. Molecular formula: C10H13ClFN3O4. Mole weight: 293.68. | |
AZ 10397767 Quick inquiry Where to buy Suppliers range | AZ 10397767 is a potent CXCR2 antagonist (IC50 = 1 nM). It significantly reduced the numbers of infiltrating neutrophils into both in vitro and in vivo tumor models and slows growing tumors. It attenuates oxaliplatin-induced NF-κB activation and increases oxaliplatin cytotoxicity, thus potentiates oxaliplatin-induced apoptosis in AIPC cells. It may be potential for treating cystic fibrosis and chronic obstructive pulmonary disease. It is orally bioavailable. Synonyms: AZ-10397767; AZ 10397767; AZ10397767. 5-[[(3-Chloro-2-fluorophenyl)methyl]thio]-7-[[(1R)-2-hydroxy-1-methylethyl]amino]thiazolo[4,5-d]pyrimidin-2(3H)-one. Grades: ≥98% by HPLC. CAS No. 333742-63-5. Molecular formula: C15H14ClFN4O2S2. Mole weight: 400.88. | |
BIS(4-METHOXY-2-NITROPHENYL)DISELENIDE Quick inquiry Where to buy Suppliers range | Bis(4-methoxy-2-nitrophenyl)diselenide, 35350-45-9, 1,2-bis(4-methoxy-2-nitrophenyl)diselane, 4-methoxy-1-[(4-methoxy-2-nitrophenyl)diselanyl]-2-nitrobenzene, DTXSID30369930, MFCD00775972, AKOS001021074, FT-0761213, BIS-(4-METHOXY-2-NITROPHENYL)DISELENIDE, Z56794904, F0400-0032, 3-Chloro-6-(2-hydroxy-ethyl)-pyrazolo[1,5-a]-pyrimidine-2-carboxylicacid. | |
Demethylpiperazinyl Desethyl Sildenafil Sulfonyl Chloride Quick inquiry Where to buy Suppliers range | Sildenafil derivative. Used in the preparation purinone derivatives for treatment of precancerous lesions and as cardiovascular agents. Group: Biochemicals. Alternative Names: 3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-hydroxy-benzenesulfonyl Chloride; 5-(5-Chlorosulfonyl-2-hydroxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one. Grades: Highly Purified. CAS No. 139756-27-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Hydroxy Chlorodenafil Quick inquiry Where to buy Suppliers range | Hydroxy Chlorodenafil is a related compound of Sildenafil as phosphodiesterase inhibitor. Group: Biochemicals. Alternative Names: 5-[5-(2-Chloro-1-hydroxyethyl)-2-ethoxyphenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one. Grades: Highly Purified. CAS No. 1391054-00-4. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
Ipatasertib HCl Quick inquiry Where to buy Suppliers range | Ipatasertib, also known as GDC-0068, is a highly selective pan-Akt inhibitor targeting Akt1/2/3 (IC50= 5 nM/18 nM/8 nM in cell-free assays) with 620-fold selectivity over PKA. Ipatasertib is advancing in clinical development including a Phase 3 trial in patients with prostate cancer and three Phase 2 trials in patients with breast cancer, gastric cancer and prostate cancer. Synonyms: (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one hydrochloride.; GDC0068; GDC-0068; GDC 0068; RG7440; RG-7440; RG 7440; Ipatasertib; Ipatasertib hydrochloride, Ipatasertib HCl. CAS No. 1489263-16-2. Molecular formula: C24H33Cl2N5O2. Mole weight: 494.46. | |
LIT-927 Quick inquiry Where to buy Suppliers range | LIT-927 is an orally available neutraligand of CXCL12. It reduces eosinophil recruitment in a murine model of allergic airway hypereosinophilia, displaying anti-inflammatory effects. Synonyms: 4-(4-Chlorophenyl)-6-(4-hydroxy-3-methoxyphenyl)pyrimidin-2(1H)-one. CAS No. 2172879-52-4. Molecular formula: C17H13ClN2O3. Mole weight: 328.75. | |
p38 MAPK-IN-2 Quick inquiry Where to buy Suppliers range | An inhibitor of p38 kinase. Synonyms: Ethanone, 1-[4-[5-(4-chloro-2-fluorophenyl)-4-(4-pyrimidinyl)-1H-pyrazol-3-yl]-1-piperidinyl]-2-hydroxy-; 1-[4-[3-(4-chloro-2-fluorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-5-yl]piperidin-1-yl]-2-hydroxyethanone. CAS No. 635725-16-5. Molecular formula: C20H19ClFN5O2. Mole weight: 415.85. | |
Paliperidone Impurity 1 Quick inquiry Where to buy Suppliers range | An impurity of Paliperidone which is the primary active metabolite of the older antipsychotic risperidone. Synonyms: 3-(2-Chloro ethyl )-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one HCl; Paliperidone Tetradehydro Chloroethyl Impurity. Grades: > 95%. CAS No. 260273-82-3. Molecular formula: C11H11ClN2O2. Mole weight: 238.68. | |
PF 06273340 Quick inquiry Where to buy Suppliers range | PF 06273340 is a potent and selective, orally bioavailable pan-Trk kinase inhibitor with IC50 of 6, 2, and 1 nM for Trk A, B and C, respectively. PF 06273340 is selective for Trk over a panel of ion channels, receptors and other enzymes. It shows efficacy in a rodent model of inflammatory pain. Synonyms: N-[5-[[2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-2-pyridineacetamide; PF-06273340; PF 06273340; PF06273340; PF-6273340; PF 6273340; PF6273340. Grades: ≥98% by HPLC. CAS No. 1402438-74-7. Molecular formula: C23H22ClN7O3. Mole weight: 479.93. | |
Ticagrelor Related Compound 18 Quick inquiry Where to buy Suppliers range | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: (1S,2S,3S,5R)-3-(2-((6-chloro-5-hydroxy-2-(propylthio)pyrimidin-4-yl)oxy)ethoxy)-5-(7-(((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2-diol. Grades: > 95%. Molecular formula: C30H35ClF2N8O5S2. Mole weight: 725.23. | |
Zunsemetinib Quick inquiry Where to buy Suppliers range | Zunsemetinib is a tyrosine kinase inhibitor. Synonyms: [1(2H),4'-Bipyridin]-2-one, 3-chloro-4-[(3,5-difluoro-2-pyridinyl)methoxy]-2'-[2-(1-hydroxy-1-methylethyl)-4-pyrimidinyl]-5',6-dimethyl-, (-)-. Grades: >98%. CAS No. 1640282-42-3. Molecular formula: C25H22ClF2N5O3. Mole weight: 513.92. |