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Acts on a variety of choline esters and a few other compounds. Group: Enzymes. Synonyms: pseudocholinesterase; butyrylcholine esterase; non-specific cholinesterase; choline esterase II (unspecific); benzoylcholinesterase; choline esterase; butyrylcholinesterase; propionylcholinesterase; BtChoEase. Enzyme Commission Number: EC 3.1.1.8. CAS No. 9001-8-5. BCHE. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3508; cholinesterase; EC 3.1.1.8; 9001-08-5; pseudocholinesterase; butyrylcholine esterase; non-specific cholinesterase; choline esterase II (unspecific); benzoylcholinesterase; choline esterase; butyrylcholinesterase; propionylcholinesterase; BtChoEase. Cat No: EXWM-3508.
Cholinesterase, Horse serum
Cholinesterase, Horse serum infers to acetylcholinesterase (AChE) and butyryl cholinesterase (BChE). AChE and BChE catalyze the hydrolysis of 6-MAM to morphine [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.1.1.8; BCHE, Horse serum. CAS No. 9001-8-5. Pack Sizes: 100 U. Product ID: HY-P2798.
acetylcholinesterase
Acts on a variety of acetic esters; also catalyses transacetylations. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl.β-methylcholinesterase; AcCholE. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3497; acetylcholinesterase; EC 3.1.1.7; 9000-81-1; true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl.β-methylcholinesterase; AcCholE. Cat No: EXWM-3497.
Acetylcholinesterase Human, Recombinant
Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Activity: > 1,000 units/mg protein (Lowry). Storage: -20°C. Form: Lyophilized powder containing phosphate buffer salt. Source: HEK 293 cells. Species: Human. Cat No: NATE-0020.
Butyrylcholinesterase (BCHE), Horse Serum
Butyrylcholinesterase (BCHE), Horse Serum (BCHE, BuChE, PCHE, pseudocholinesterase, plasma cholinesterase, Acylcholine acyl-hydrolase, Choline esterase, butyryl) is a biological material or organic compound that can be used in life science research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCHE, BuChE, PCHE, pseudocholinesterase, plasma cholinesterase, Acylcholine acyl-hydrolase, Choline esterase, butyryl. Pack Sizes: 200 U; 500 U. Product ID: HY-E70362.
Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. Type vi-s, lyophilized powder, 200-1000 units/mg protein; type v-s, lyophilized powder, > 1000 units/mg protein. Applications: The enzyme has been used as a reference to to evaluate the effect of aspartame metabolites on hippocampal acetylcholinesterase activity. the enzyme has also been used in immobilization studies for the rapid detection of acetylthiocholine chloride. Group: Enzymes. Synonyms: true c. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Mole weight: 280 kDa. Activity: > 1 ,000 units/mg protein; 200-1 ,000 units/mg protein. Storage: -20°C. Form: lyophilized powder. Source: Electrophorus electricus (electric eel). true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Cat No: NATE-0018.
Native Equine Butyrylcholinesterase
Butyrylcholinesterase (BChE) is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE), but differs in substRate specificities and inhibitor sensitivities. BChE can, unlike AChE, efficiently hydrolyze larger esters of choline such as butyrylcholine and benzoylcholine. The enzyme is a tetrameric glycoprotein with four equal subunits (110 kDa each). The enzyme is activated by Ca2+ and Mg2+ and the activity is constant over the pH range 6.0-8.0. It is inhibited by Betaine, nicotine, organophosphates, carbamates. This product is prepared from equine serum using ammonium sulfate fractionation and supplied as a lyophilized powder. Applications: Butyrylchol...vestigations into selective inhibitors may provide a clearer picture of the physiological role of bche in both healthy and diseased individuals. this product has been used for the screening of cholineesterase inhibitors in selected fruits and vegetables, for restoring cognitive function and improving memory. it has also been used to develop a butyrylcholinesterase and choline oxidase immobilized bio-sniffer for the detection of nicotine. nicotine inhibits bche activity. a decrease in the byproducts of bche activity reflects the volume of nicotine. Group: Enzymes. Synonyms: Butyrylcholinesterase; BCHE; BuChE; pseudocholinesterase; plasma cholinesterase; EC 3.1.1.8; 9001-08-5;
Native Human Butyrylcholinesterase
Butyrylcholinesterase (BChE) is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE), but differs in substRate specificities and inhibitor sensitivities. BChE can, unlike AChE, efficiently hydrolyze larger esters of choline such as butyrylcholine and benzoylcholine. The enzyme is a tetrameric glycoprotein with four equal subunits (110 kDa each). The enzyme is activated by Ca2+ and Mg2+ and the activity is constant over the pH range 6.0-8.0. It is inhibited by Betaine, nicotine, organophosphates, carbamates. Applications: Butyrylcholinesterase (bche) is a serine hydrolase that shares substantial structural similarities with acetylcholinesterase (ache) but has different substrate and inhibitor specificities. bche is found in the serum, hemopoietic cells, liver, lung, heart and the central nervous system of vertebrates. Group: Enzymes. Synonyms: Butyrylcholinesterase; BCHE; BuChE; pseudocholinesterase; plasma cholinesterase; EC 3.1.1.8; 9001-08-5; Acylcholine acyl-hydrolase; Choline esterase; butyryl. Enzyme Commission Number: EC 3.1.1.8. CAS No. 9001-8-5. BCHE. Activity: > 50 U/mg protein. Source: Human serum. Species: Human. Butyrylcholinesterase; BCHE; BuChE; pseudocholinesterase; plasma cholinesterase; EC 3.1.1.8; 9001-08-5; Acylcholine acyl-hydrolase; Choline esterase; butyryl. Cat No: NATE-0093.
Native Human erythrocytes Acetylcholinesterase
Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. The activity obtained using acetylcholine as substrate is 30-100 times that obtained with butyrylcholine, using acetylcholinesterase from electric eel. Applications: Acetylcholinesterase (ache) from creative enzymes has been used in the structure-activity study of phosphoramido acid esters as inhibitors of ache. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholines. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Mole weight: ~80 kDa. Activity: > 500 units/mg protein (BCA). Storage: 2-8°C. Form: buffered aqueous solution. Solution in 20 mM HEPES, pH 8.0, containing 0.1% TRITON X-100. Source: Human erythrocytes. Species: Human. true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Cat No: NATE-0019.
1,3-Diaminopropane-d6
1,3-Diaminopropane-d6 is the isotope labelled analog of 1,3-Diaminopropane. 1,3-Diaminopropane is a common chemical reagent, used in the synthesis of 7-methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors applied in the treatment of Alzheimers disease. Also used in the synthesis of thrombosis inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 90375-98-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C3H4D6N2, Molecular Weight: 80.16. US Biological Life Sciences.
Worldwide
1-(3-Methoxyphenyl)ethanol
A impurity of Rivastigmine.Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: 1-(3-methoxyphenyl)ethanol; 1-(3-methoxyphenyl)ethanol. Grade: 99 %. CAS No. 23308-82-9. Molecular formula: C9H12O2. Mole weight: 152.19.
1,8-Dibromooctane
1,8-Dibromooctane is used as a reagent in the synthesis of novel 7-aminoalkyl-substituted flavonoid derivatives as potential cholinesterase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 4549-32-0. Pack Sizes: 1g, 5g. Molecular Formula: C8H16Br2, Molecular Weight: 272.02. US Biological Life Sciences.
1-[ (Chloromethoxy)methyl]-2-[ (hydroxyimino)methyl]-pyridinium Chloride is an intermediate of Asoxime Chloride (A790000), cholinesterase reactivator. A potential antidote for organophosphate poisoning. Group: Biochemicals. Grades: Highly Purified. CAS No. 27123-11-1. Pack Sizes: 250mg, 500mg. Molecular Formula: C8H10Cl2N2O2. US Biological Life Sciences.
Worldwide
1-Ethyl-3-hydroxypiperidine
1-Ethyl-3-hydroxypiperidine acts as a reagent for the preparation of new compounds of N, N-dimethyl-[3- (1-alkylpiperidy) ]carbamates, as potential cholinesterase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 13444-24-1. Pack Sizes: 1g, 2.5g. Molecular Formula: C7H15NO, Molecular Weight: 129.199999999999. US Biological Life Sciences.
Worldwide
1-Hydroxy Tacrine
One of the impurities of Tacrine, which is an effective cholinesterase inhibitor and could probably be active in studies of Alzheimers's disease. Uses: Cholinesterase inhibitors. Synonyms: 1-Hydroxy Tacrine. Grade: > 95%. CAS No. 124027-47-0. Molecular formula: C13H14N2O. Mole weight: 214.27.
1-Hydroxy Tacrine-d4 HCl
One of the isotopic labelled impurities of Tacrine, which is an effective cholinesterase inhibitor and could probably be active in studies of Alzheimers's disease. Synonyms: 1-Hydroxy Tacrine-d4 HCl. Grade: > 95%. CAS No. 1246816-08-9. Molecular formula: C13H10N2OD4·HCl. Mole weight: 254.75.
1-Hydroxy Tacrine Maleate
One of the impurities of Tacrine, which is an effective cholinesterase inhibitor and could probably be active in studies of Alzheimers's disease. Uses: Cholinesterase inhibitors. Synonyms: 1-Hydroxy Tacrine Maleate; 9-Amino-1,2,3,4-tetrahydroacridin-1-ol Maleate; 9-Amino-1,2,3,4-tetrahydro-1-acridinol (2Z)-2-Butenedioate; HP 029; Mentane; P 83-6029A; Velnacrine Hydrogen Maleate; Velnacrine Maleate. Grade: > 95%. CAS No. 118909-22-1. Molecular formula: C13H14N2O. C4H4O4. Mole weight: 330.33.
2,3-Butanedione-2-monoxime
2,3-Butanedione-2-monoxime (BDM) is a non-selective, reversible myosin ATPase inhibitor with phosphatase-like properties. It is non-selective myosin ATPase inhibitor (Ki = 5 mM at myosin II). Uses: Cholinesterase reactivators. Synonyms: BDM; Diacetyl Monoxime; NSC 660; NSC 116103; Biacetyl monooxime. Grade: ≥95%. CAS No. 57-71-6. Molecular formula: C4H7NO2. Mole weight: 101.1.
2,6-Dihydroxybenzaldehyde
2,6-Dihydroxybenzaldehyde is a reactant used in the synthesis of cinnamides as potent cholinesterase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 387-46-2. Pack Sizes: 1g, 2.5g, 5g. Molecular Formula: C7H6O3, Molecular Weight: 138.12. US Biological Life Sciences.
Worldwide
(2E) -2- [ (3-Methoxyphenyl ) methy l ene ] hydrazinecar bothioamide
(2E) -2- [ (3-Methoxyphenyl ) methy l ene ] hydrazinecar bothioamide used in the development of new potent and selective cholinesterase inhibitors, which might be further optimized to prevent the progression of the Alzheimer's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 1334180-01-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H11N3OS, Molecular Weight: 209.27. US Biological Life Sciences.
Worldwide
2-Ethyl-2-methyl-1,3-dioxolane
2-Ethyl-2-methyl-1,3-dioxolane is used as a reagent in the synthesis of Strychnine Hydrochloride (S687710); a compound that acts as an antagonist for cholinesterases and beta amyloid aggregation. Also used as a reagent in the study of the prodrugs of peptide aldehyde as proteasome inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 126-39-6. Pack Sizes: 1g, 10g. Molecular Formula: C6H12O2, Molecular Weight: 116.16. US Biological Life Sciences.
Worldwide
2-Hydroxydocosanoic acid
2-Hydroxydocosanoic acid has antioxidant, cholinesterase inhibitory, and antimicrobial activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 13980-14-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-122790.
(2R)-Eriodictyol
(2R)-Eriodictyol is the 2R-enantiomer of Eriodictyol (E600085); used in biological studies as natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation. Eriodictyl is extracted from Yerba santa, an herb. The leaf is used to make medicine. Group: Biochemicals. Grades: Highly Purified. CAS No. 116301-03-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C15H12O6, Molecular Weight: 288.25. US Biological Life Sciences.
Worldwide
3-(1-Azepanyl)-1-propanamine
3-(1-Azepanyl)-1-propanamine refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases. Group: Biochemicals. Grades: Highly Purified. CAS No. 3437-33-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C9H20N2. US Biological Life Sciences.
Worldwide
3-(1-Dimethylaminoethyl)phenol
An active (major) metabolite of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: Phenol, 3-[1-(dimethylamino)ethyl]-; 3-[(1S)-1-(Dimethylaminoethyl)]phenol. Grade: 95%. CAS No. 105601-04-5. Molecular formula: C10H15NO. Mole weight: 165.23.
3'-Methoxyacetophenone
A impurity of Rivastigmine.Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: 1-(3-methoxyphenyl)ethanone. Grade: 99 %. CAS No. 586-37-8. Molecular formula: C9H10O2. Mole weight: 150.17.
4-(1-(dimethylamino)ethyl)phenol hydrochloride
An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: Dimethyl-alpha-(4-hydroxyphenyl)ethylamine hydrochloride; p-(1-(Dimethylamino)ethyl)phenol hydrochloride; Rivastigmine Impurity 11. CAS No. 1049692-05-8. Molecular formula: C10H16ClNO. Mole weight: 201.69.
9-Amino-1,2,3,4-tetrahydroacridin-1-ol-[d3] Maleate is the labelled analogue of 9-Amino-1,2,3,4-tetrahydroacridin-1-ol Maleate, which is an impurity of Tacrine. Tacrine is an effective cholinesterase inhibitor and could probably be active in studies of Alzheimers's disease. Synonyms: 9-Amino-1,2,3,4-tetrahydroacridin-1-ol-d3 Maleate; 9-Amino-1,2,3,4-tetrahydro-1-acridinol-d3 Maleate; HP 029-d3 Maleate; Mentane-d3 Maleate; Velnacrine-d3 Maleate; 1-hydroxy tacrine-d3 Maleate; 9-Amino-1,2,3,4-tetrahydroacridin-1,2,2-d3-1-ol maleate; (±)-Velnacrine-1,2,2-d3 Maleate. Grade: 95% by HPLC; 98% atom D. CAS No. 1219806-48-0. Molecular formula: C17H15D3N2O5. Mole weight: 333.36.
Acephate
Acephate is a broad-spectrum anticholinesterase insecticide. Acephate acts via inhibiting AChE ( Cholinesterase (ChE) ) activity of insects. Acephate is used for control of several species of insects in agriculture and in horticulture [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 30560-19-1. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0841.
acetylsalicylate deacetylase
Not identical with EC 3.1.1.1 (carboxylesterase), EC 3.1.1.2 (arylesterase), EC 3.1.1.7 (acetylcholinesterase) or EC 3.1.1.8 (cholinesterase). The activity of the liver cytosol enzyme is highest with acetyl esters of aryl alcohols, and thioesters are also hydrolysed; the microsomal enzyme also hydrolyses some other negatively charged esters, with highest activity on esters of salicylate with long-chain alcohols. Group: Enzymes. Synonyms: aspirin esterase; aspirin esterase; acetylsalicylic acid esterase; aspirin hydrolase. Enzyme Commission Number: EC 3.1.1.55. CAS No. 87348-04-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3483; acetylsalicylate deacetylase; EC 3.1.1.55; 87348-04-7; aspirin esterase; aspirin esterase; acetylsalicylic acid esterase; aspirin hydrolase. Cat No: EXWM-3483.
Acetylthiocholine iodide
Acetylthiocholine iodide can be used as a substrate for certain enzymes, such as cholinesterase, etc., and can be used to determine the activity level of these enzymes. In addition, the compound is used in some medical research, for example in the fields of neuroscience and organ physiology. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: S-Acetylthiocholine iodide; ATCh iodide. CAS No. 1866-15-5. Pack Sizes: 10 g. Product ID: HY-D0904.
Acotiamide
Acotiamide is a potent and seletive inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Synonyms: Acotiamide; MZ-338; UNII-D42OWK5383. CAS No. 185106-16-5. Molecular formula: C21H30N4O5S. Mole weight: 450.554.
Acotiamide hydrochloride trihydrate
Acotiamide, also known as YM-443 and Z-338, is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Synonyms: N-(2-(diisopropylamino)ethyl)-2-(2-hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxamide hydrochloride trihydrate; YM443; YM-443; YM 443; Z338; Z-338; Z 338; Acotiamide; Acotiamide hydrochloride trihydrate; Brand name: Acofide. Grade: 98%. CAS No. 773092-05-0. Molecular formula: C21H37ClN4O8S. Mole weight: 541.06.
Aldicarb sulfone
Aldicarb sulfone(Temik sulfone) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse. Uses: Scientific research. Group: Signaling pathways. CAS No. 1646-88-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-17530.
Altenuene
(-)-Altenuene is a toxin isolated from the fungus Alternaria tenuis. It has antioxidant activity and inhibits cholinesterases. Synonyms: (2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one. Grade: >95%. CAS No. 29752-43-0. Molecular formula: C15H16O6. Mole weight: 292.29.
(-)-Altenuene-[d6]
Labelled (-)-Altenuene. (-)-Altenuene is a toxin isolated from the fungus Alternaria tenuis. It has antioxidant activity and inhibits cholinesterases. Molecular formula: C15H10D6O6. Mole weight: 298.32.
Alternariol monomethyl ether
The 50 ppm acetonitrile solution of Alternariol monomethyl ether, shows activities as a cholinesterase inhibitor as well as an anti-fungal agent, could be commonly used as a standard solution. It is an alternaria mycotoxin and genotoxin, which can inhibit the activity of DNA-topoisomerases. Synonyms: 6H-Dibenzo[b,d]pyran-6-one, 3,7(3,9 or 7,9)-dihydroxy-9(7 or 3)-methoxy-1-methyl-; 3,7(3,9 or 7,9)-Dihydroxy-9(7 or 3)-methoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one; Alternariol, methyl ether. Grade: >95%. CAS No. 26894-49-5. Molecular formula: C15H12O5. Mole weight: 272.25.
Ambenonium
Ambenonium is a long-acting cholinesterase inhibitor used as a treatment of myasthenia gravis. The mechanism of Ambenonium is similar to neostigmine. Synonyms: Win-8077; N,N'-[(1,2-Dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl)]bis[2-chloro-N,N-diethylbenzenemethanaminium]. CAS No. 7648-98-8. Molecular formula: C28H42Cl2N4O2. Mole weight: 537.57.
AP2238
AP2238 is a inhibitor of both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Uses: Cholinesterase inhibitors. Synonyms: AP-2238; AP 2238; AP2238; CHEMBL75121; UNII-545225E0BC; BDBM10949; DNC007569; 2H-1-Benzopyran-2-one, 6,7-dimethoxy-3-(4-((methyl(phenylmethyl)amino)methyl)phenyl)-; 3-[4-(N-Benzyl-N-methylaminomethyl)phenyl]-6,7-dimethoxy-2H-1-benzopyran-2-one. Grade: 98%. CAS No. 553681-56-4. Molecular formula: C26H25NO4. Mole weight: 415.48.
Asoxime Chloride
Cholinesterase reactivator. A potential antidote for organophosphate poisoning. Synonyms: 1[[[4-(Aminocarbonyl)pyridinio]methoxy]methyl]-2-[(hydroxyimino)methyl]pyridinium Dichloride. Grade: > 95%. CAS No. 34433-31-3. Molecular formula: C14H16N4O3.2 Cl. Mole weight: 359.21.
Cholinesterase reactivator. A potential antidote for organophosphate poisoning. Group: Biochemicals. Alternative Names: 1 [ [ [4- (Aminocarbonyl) pyridinio] methoxy] methyl] -2- [ (hydroxyimino) methyl] pyridinium Dichloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Asoxime-d4 Chloride
Asoxime-d4 Chloride is a labelled Asoxime Chloride. Asoxime Chloride is a cholinesterase reactivator used in the treatment of organophosphate poisoning. Synonyms: 1[[[4-(Aminocarbonyl)pyridinio-d4]methoxy]methyl]-2-[(hydroxyimino)methyl]pyridinium Dichloride; HI 6-d4 Chloride; HJ 6-d4. Grade: > 95%. Molecular formula: C14H12N4O3D4·2Cl. Mole weight: 363.23.
bis(7)-Tacrine
Acetylcholinesterase (AChE) is the primary cholinesterase in the body. It is an enzyme catalyzing the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. Tacrine is an amino acridine compound that inhibits acetylcholinesterase (AChE), which has been proposed as a clinical treatment for Alzheimer's disease. Bis(7)-Tacrine is a tacrine dimer, linked via a 7-carbon alkyl spacer. It inhibits AChE with an IC50 of 0.40 nM, making it more than 1,000 times more potent than tacrine. It is thought to have multiple mechanisms of action including inhibition of AChE, and inihbititon of the amyloid precursor protein/beta-amyloid cascade. It has been shown to inhibit the formation of Aβ1-42 oligomers and reduce the amount of pre-formed Aβ1-42 oligomers. Synonyms: 1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydro-acridine. Grade: ≥98%. CAS No. 224445-12-9. Molecular formula: C33H40N4·2HCl. Mole weight: 565.6.
Carbachol (Carbamylcholine Chloride)
Carbamylcholine Chloride is a cholinergic receptor agonist. Studies show that Carbamylcholine Chloride is resistant to the action of cholinesterases. Carbamylcholine Chloride also displays antiapoptotic effects in cerebellar granule neurons. Group: Biochemicals. Alternative Names: (2-Carbamoyloxyethyl) trimethylammonium Chloride; (2-Hydroxyethyl)trimethyl ammonium Chloride Carbamate; Carbachol; Carbachol Chloride; Carbacholin; Carbacholine; Carbacholine Chloride; Carbacolina; Carbaminocholine Chloride; Carbaminoylcholine Chloride; Carbamiotin; Carbamoylcholine Chloride; Carbamoylcholine-hydrochloride; Carbastat Intraocular; Carbochol; Carbocholin; Carbocholine; Carbyl; Carcholin; Choline Carbamate Chloride; Coletyl; Doryl; Doryl (pharmaceutical); Isopto Carbachol; Jestryl; Lentin; Miostat; Moryl; Vasoperif; γ-Carbamoyl Choline Chloride. Grades: Highly Purified. CAS No. 51-83-2. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences.
Worldwide
Carbaryl
Cholinesterase inhibitor. Ectoparasiticide. Group: Biochemicals. Alternative Names: 1-Naphthyl N-Methylcarbamate; 1-Naphthalenol Methylcarbamate; 1-Naphtyl N-Methylcarbamate; ENT-23969; OMS-29; UC-7744; Carylderm; Derbac; Ravyon; Sevin. Grades: Highly Purified. CAS No. 63-25-2. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Carbaryl-[d3]
Carbaryl-[d3] is the labelled analogue of Carbaryl, which is used as an insecticide and a veterinary drug. It has a role as a cholinesterase inhibitor, an acaricide, an agrochemical and a plant growth retardant. Synonyms: Carbaryl-D3; Carbaryl-(methyl-d3); 1-Naphthol-N-methyl-D3-carbamate; N-(methyl-d3)-1-naphthalenyl ester carbamic acid; 1-Naphthalenol Methylcarbamate-d3; Carylderm-d3; Derbac-d3; Ravyon-d3; Sevin-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 1433961-56-8. Molecular formula: C12H8D3NO2. Mole weight: 204.24.
Carbaryl-[d7]
Carbaryl-[d7] is the labelled analogue of Carbaryl, which has a role as an acetylcholinesterase inhibitor, a carbamate insecticide, a cholinesterase inhibitor, an acaricide, an agrochemical and a plant growth retardant. Uses: Cholinesterase inhibitor. Synonyms: Carbaryl D7; 1-Naphthyl-d7 N-Methylcarbamate; 1-Naphthalenol Methylcarbamate-d7; 1-Naphtyl N-Methylcarbamate-d7; ENT-23969-d7; OMS-29-d7; UC-7744-d7; Carylderm-d7; Derbac-d7; Ravyon-d7; Sevin-d7. Grade: ≥98%; ≥98% atom D. CAS No. 362049-56-7. Molecular formula: C12H4D7NO2. Mole weight: 208.26.
Cholinesterase inhibitor. Group: Biochemicals. Alternative Names: 1-Naphthalenol Methylcarbamate-d7; 1-Naphtyl N-Methylcarbamate-d7; ENT-23969-d7; OMS-29-d7; UC-7744-d7; Carylderm-d7; Derbac-d7; Ravyon-d7; Sevin-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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(Carbethoxymethylene) triphenylphosphorane
A common Wittig reagent. A cholinesterase inhibitor. Group: Biochemicals. Alternative Names: 2- (tri phenylphosphoranylide ne ) acetic Acid Ethyl Ester; (2-Ethoxy-2-oxoethylidene) triphenylphosphorane; Ethyl (tri phenylphosphoranylide ne ) acetate; NSC 72406. Grades: Highly Purified. CAS No. 1099-45-2. Pack Sizes: 50g. US Biological Life Sciences.
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Carbofuran
Cholinesterase inhibitor. Use as systemic insecticide, acaricide, nematocide. Group: Biochemicals. Alternative Names: 2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-Methylcarbamate; Bay 70143; NIA-10242; Furadan. Grades: Highly Purified. CAS No. 1563-66-2. Pack Sizes: 10g. US Biological Life Sciences.
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Carbofuran-d3 (2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-Methylcarbamate-d3, Bay 70143-d3, NIA-10242-d3, Furadan-d3)
Cholinesterase inhibitor. Use as systemic insecticide, acaricide, nematocide. Group: Biochemicals. Alternative Names: 2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-Methylcarbamate-d3; Bay 70143-d3; NIA-10242-d3; Furadan-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Chavicol
Chavicol (p-Hydroxyallylbenzene, compound 6) can inhibit acetylcholinesterase ( Cholinesterase (ChE) ), with an IC 50 of 7.42 μM. Chavicol has anti-cancer activity and can suppress the growth, survival, migration, and invasion of cancer cells. Chavicol cytotoxic effect is significant, approximately 31 μg/mL in A-549 cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: p-Hydroxyallylbenzene. CAS No. 501-92-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W159754.
Cyclanoline chloride
Cyclanoline chloride is a cholinesterase inhibitor. Synonyms: Cissamine chloride; l-alpha-N-Methylscoulerine. CAS No. 17472-50-3. Molecular formula: C20H24ClNO4. Mole weight: 377.86.
Demecarium is a parasympathomimetic that acts as an acetylcholinesterase inhibitor. It is one of several topical (applied directly to the affected area) medications used to reduce elevated intraocular pressure (IOP) associated with primary glaucoma in cats, dogs, and other animals. Uses: Cholinesterase inhibitors; miotics. Synonyms: 3,3'-[1,10-decanediylbis[(methylimino)carbonyloxy]]bis[N,N,N-trimethylbenzenaminium Bromide; (m-Hydroxyphenyl)trimethylammonium Bromide Decamethylenebis[methylcarbamate]; (m-hydroxyphenyl)trimethylammonium Bromide Decamethylenebis[methylcarbamate]; Demekarium Bromide; Demekastigmine Bromide; Frumtosnil; Humorsol. Grade: ≥95%. CAS No. 56-94-0. Molecular formula: White Solid. Mole weight: 716.59.
Demecarium Bromide
Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor, with an apparent affinity ( K iapp ) of 0.15 μM [1]. Demecarium Bromide (BC-48) is used as a glaucoma agent [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BC-48. CAS No. 56-94-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1626A.
Desbenzyl Donepezil Hydrochloride
Desbenzyl Donepezil Hydrochloride is an impurity of Donepezil, which is a centrally acting reversible acetyl cholinesterase inhibitor for the treatment of moderate to severe Alzheimer's disease. Synonyms: 5,6-Dimethoxy-2-[(4-piperidyl)methyl]-1-indanone Hydrochloride; 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-, hydrochloride (1:1); 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-, monohydrochloride; 4-[(5,6-Dimethoxy-1-oxoindan-2-yl)methyl]piperidine hydrochloride; Donepezil Desbenzyl Impurity. Grade: ≥95%. CAS No. 120013-39-0. Molecular formula: C17H24ClNO3. Mole weight: 325.83.
Desoxypeganine hydrochloride
A substance which inhibits cholinesterases reversibly. Alkaloid , from plants of the Zygophyllaceae family. Synonyms: Deoxyvasicine hydrochloride; 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline hydrochloride. Grade: 98% (HPLC). CAS No. 61939-05-7. Molecular formula: C11H13ClN2. Mole weight: 208.69.
Diazinon
A cholinesterase inhibitor; a nonsystemic organophosphate insecticide. Group: Biochemicals. Alternative Names: O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate; NSC 8938; Oleodiazinon; Phosphorothioc Acid O,O-Diethyl O-[6-Methyl-2-(1-methylethyl)-4-pyrimidinyl] Ester. Grades: Highly Purified. CAS No. 333-41-5. Pack Sizes: 1g. US Biological Life Sciences.
Cholinesterase inhibitor. Group: Biochemicals. Alternative Names: Diazinon-diethyl-d10; Phosphorothioc Acid O,O-diethyl-d10 O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl]ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Dichlorvos
Cholinesterase inhibitor. Anthelmintic, insecticide. Group: Biochemicals. Alternative Names: Phosphoric Acid 2,2-Dichloroethenyl Dimethyl Ester; Dichlorophos; DDVP; SD-1750; Task; Vapona. Grades: Highly Purified. CAS No. 62-73-7. Pack Sizes: 500mg. US Biological Life Sciences.
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Dichlorvos-[d6]
Dichlorvos-[d6] is the labelled analogue of Dichlorvos. Dichlorvos is an organophosphate widely used as an insecticide to control household pests, in public health, and protect stored products from insects. Uses: Cholinesterase inhibitor. anthelmintic, insecticide. Synonyms: Dichlorvos D6; Phosphoric Acid 2,2-Dichloroethenyl Dimethyl Ester-d6; Dichlorophos-d6; DDVP-d6; SD-1750-d6; Task-d6; Vapona-d6; Dichlorvos-(dimethyl-d6). Grade: 98% by CP; 98% atom D. CAS No. 203645-53-8. Molecular formula: C4HD6Cl2O4P. Mole weight: 227.01.
Cholinesterase inhibitor. Anthelmintic, insecticide. Group: Biochemicals. Alternative Names: Phosphoric Acid 2,2-Dichloroethenyl Dimethyl Ester-d6; Dichlorophos-d6; DDVP-d6; SD-1750-d6; Task-d6; Vapona-d6. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Diethyl Rivastigmine
An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: Rivastigmine Diethyl Analog; Carbamic acid, N,N-diethyl-, 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester. CAS No. 1230021-34-7. Molecular formula: C15H24N2O2. Mole weight: 264.36.
Distigmine
Distigmine is a cholinesterase inhibitor used for the treatment of neurogenic bladder dysfunction or myasthenia gravis. Synonyms: Distigmine ion. CAS No. 17299-00-2. Molecular formula: C22H32N4O4. Mole weight: 416.5.
Donepezil
Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one; (±)-E 2020; 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine; Neuripezil; Tonizep; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Aricept; HSDB 7743; HSDB7743; HSDB-7743; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Eranz; Aricept ODT; donepezilo; donepezilum; CHEMBL502; donepezil hydrochloride; donepezilium oxalate trihydrate; E 2020; E-2020; E2020; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; (RS)-2-[(1-BENZYL-PIPERIDIN-4-YL)METHYL]-5,6-DIMETHOXYINDAN-1-ONE. Grade: > 98%. CAS No. 120014-06-4. Molecular formula: C24H29NO3. Mole weight: 379.49.
(-)-Donepezil
(-)-Donepezil is one of Donepezil isomers. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Uses: Cholinesterase inhibitors; nootropic agents. Synonyms: (S)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-Inden-1-one; (2S)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one; (S)-Donepezil; (S)-Aricept; (2S)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one. Grade: ≥95%. CAS No. 142057-80-5. Molecular formula: C24H29NO3. Mole weight: 379.49.
Donepezil-D5 hydrochloride
One of the isotopic labelled form of donepezil, which is a cholinesterase inhibitor. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-[[1-((phenyl-d5)methyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride. Grade: ≥98% by HPLC; 98% atom D. Molecular formula: C24H24D5NO3.HCl. Mole weight: 420.99.
Donepezil hydrochloride
Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively. Uses: Cholinesterase inhibitors. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-oneHydrochloride; Aricept; Aricept D; BNAG; Donepezil HCl; BNAG; donepezilium oxalate trihydrate; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride. Grade: ≥ 95%. CAS No. 120011-70-3. Molecular formula: C24H30ClNO3. Mole weight: 415.95.
Doxacurium Chloride (Mixture of Diastereomers)
Doxacurium Chloride is a nondepolarizing neuromuscular blocking agent that is minimally hydrolyzed by human plasma cholinesterase. Group: Biochemicals. Grades: Highly Purified. CAS No. 106819-53-8. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C56H78Cl2N2O16, Molecular Weight: 1106.13. US Biological Life Sciences.
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