Cholinesterase Suppliers USA

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cholinesterase Acts on a variety of choline esters and a few other compounds. Group: Enzymes. Synonyms: pseudocholinesterase; butyrylcholine esterase; non-specific cholinesterase; choline esterase II (unspecific); benzoylcholinesterase; choline esterase; butyrylcholinesterase; propionylcholinesterase; BtChoEase. Enzyme Commission Number: EC 3.1.1.8. CAS No. 9001-8-5. BCHE. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3508; cholinesterase; EC 3.1.1.8; 9001-08-5; pseudocholinesterase; butyrylcholine esterase; non-specific cholinesterase; choline esterase II (unspecific); benzoylcholinesterase; choline esterase; butyrylcholinesterase; propionylcholinesterase; BtChoEase. Cat No: EXWM-3508. Creative Enzymes
Cholinesterase, Horse serum Cholinesterase, Horse serum infers to acetylcholinesterase (AChE) and butyryl cholinesterase (BChE). AChE and BChE catalyze the hydrolysis of 6-MAM to morphine [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.1.1.8; BCHE, Horse serum. CAS No. 9001-8-5. Pack Sizes: 100 U. Product ID: HY-P2798. MedChemExpress MCE
acetylcholinesterase Acts on a variety of acetic esters; also catalyses transacetylations. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl.β-methylcholinesterase; AcCholE. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3497; acetylcholinesterase; EC 3.1.1.7; 9000-81-1; true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl.β-methylcholinesterase; AcCholE. Cat No: EXWM-3497. Creative Enzymes
Acetylcholinesterase Human, Recombinant Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Activity: > 1,000 units/mg protein (Lowry). Storage: -20°C. Form: Lyophilized powder containing phosphate buffer salt. Source: HEK 293 cells. Species: Human. Cat No: NATE-0020. Creative Enzymes
Native Electrophorus electricus (electric eel) Acetylcholinesterase Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. Type vi-s, lyophilized powder, 200-1000 units/mg protein; type v-s, lyophilized powder, > 1000 units/mg protein. Applications: The enzyme has been used as a reference to to evaluate the effect of aspartame metabolites on hippocampal acetylcholinesterase activity. the enzyme has also been used in immobilization studies for the rapid detection of acetylthiocholine chloride. Group: Enzymes. Synonyms: true c. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Mole weight: 280 kDa. Activity: > 1 ,000 units/mg protein; 200-1 ,000 units/mg protein. Storage: -20°C. Form: lyophilized powder. Source: Electrophorus electricus (electric eel). true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Cat No: NATE-0018. Creative Enzymes
Native Equine Butyrylcholinesterase Butyrylcholinesterase (BChE) is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE), but differs in substRate specificities and inhibitor sensitivities. BChE can, unlike AChE, efficiently hydrolyze larger esters of choline such as butyrylcholine and benzoylcholine. The enzyme is a tetrameric glycoprotein with four equal subunits (110 kDa each). The enzyme is activated by Ca2+ and Mg2+ and the activity is constant over the pH range 6.0-8.0. It is inhibited by Betaine, nicotine, organophosphates, carbamates. This product is prepared from equine serum using ammonium sulfate fractionation and supplied as a lyophilized powder. Applications: Butyrylchol...vestigations into selective inhibitors may provide a clearer picture of the physiological role of bche in both healthy and diseased individuals. this product has been used for the screening of cholineesterase inhibitors in selected fruits and vegetables, for restoring cognitive function and improving memory. it has also been used to develop a butyrylcholinesterase and choline oxidase immobilized bio-sniffer for the detection of nicotine. nicotine inhibits bche activity. a decrease in the byproducts of bche activity reflects the volume of nicotine. Group: Enzymes. Synonyms: Butyrylcholinesterase; BCHE; BuChE; pseudocholinesterase; plasma cholinesterase; EC 3.1.1.8; 9001-08-5; Creative Enzymes
Native Human Butyrylcholinesterase Butyrylcholinesterase (BChE) is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE), but differs in substRate specificities and inhibitor sensitivities. BChE can, unlike AChE, efficiently hydrolyze larger esters of choline such as butyrylcholine and benzoylcholine. The enzyme is a tetrameric glycoprotein with four equal subunits (110 kDa each). The enzyme is activated by Ca2+ and Mg2+ and the activity is constant over the pH range 6.0-8.0. It is inhibited by Betaine, nicotine, organophosphates, carbamates. Applications: Butyrylcholinesterase (bche) is a serine hydrolase that shares substantial structural similarities with acetylcholinesterase (ache) but has different substrate and inhibitor specificities. bche is found in the serum, hemopoietic cells, liver, lung, heart and the central nervous system of vertebrates. Group: Enzymes. Synonyms: Butyrylcholinesterase; BCHE; BuChE; pseudocholinesterase; plasma cholinesterase; EC 3.1.1.8; 9001-08-5; Acylcholine acyl-hydrolase; Choline esterase; butyryl. Enzyme Commission Number: EC 3.1.1.8. CAS No. 9001-8-5. BCHE. Activity: > 50 U/mg protein. Source: Human serum. Species: Human. Butyrylcholinesterase; BCHE; BuChE; pseudocholinesterase; plasma cholinesterase; EC 3.1.1.8; 9001-08-5; Acylcholine acyl-hydrolase; Choline esterase; butyryl. Cat No: NATE-0093. Creative Enzymes
Native Human erythrocytes Acetylcholinesterase Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. The activity obtained using acetylcholine as substrate is 30-100 times that obtained with butyrylcholine, using acetylcholinesterase from electric eel. Applications: Acetylcholinesterase (ache) from creative enzymes has been used in the structure-activity study of phosphoramido acid esters as inhibitors of ache. Group: Enzymes. Synonyms: true cholinesterase; choline esterase I; cholines. Enzyme Commission Number: EC 3.1.1.7. CAS No. 9000-81-1. Acetylcholinesterase. Mole weight: ~80 kDa. Activity: > 500 units/mg protein (BCA). Storage: 2-8°C. Form: buffered aqueous solution. Solution in 20 mM HEPES, pH 8.0, containing 0.1% TRITON X-100. Source: Human erythrocytes. Species: Human. true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase. Cat No: NATE-0019. Creative Enzymes
1,3-Diaminopropane-d6 1,3-Diaminopropane-d6 is the isotope labelled analog of 1,3-Diaminopropane. 1,3-Diaminopropane is a common chemical reagent, used in the synthesis of 7-methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors applied in the treatment of Alzheimer’s disease. Also used in the synthesis of thrombosis inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 90375-98-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C3H4D6N2, Molecular Weight: 80.16. US Biological Life Sciences. USBiological 9
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1-(3-Methoxyphenyl)ethanol A impurity of Rivastigmine.Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: 1-(3-methoxyphenyl)ethanol; 1-(3-methoxyphenyl)ethanol. Grades: 99 %. CAS No. 23308-82-9. Molecular formula: C9H12O2. Mole weight: 152.19. BOC Sciences 7
1,8-Dibromooctane 1,8-Dibromooctane is used as a reagent in the synthesis of novel 7-aminoalkyl-substituted flavonoid derivatives as potential cholinesterase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 4549-32-0. Pack Sizes: 1g, 5g. Molecular Formula: C8H16Br2, Molecular Weight: 272.02. US Biological Life Sciences. USBiological 9
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1-[ (Chloromethoxy)methyl]-2-[ (hydroxyimino)methyl]-pyridinium Chloride 1-[ (Chloromethoxy)methyl]-2-[ (hydroxyimino)methyl]-pyridinium Chloride is an intermediate of Asoxime Chloride (A790000), cholinesterase reactivator. A potential antidote for organophosphate poisoning. Group: Biochemicals. Grades: Highly Purified. CAS No. 27123-11-1. Pack Sizes: 250mg, 500mg. Molecular Formula: C8H10Cl2N2O2. US Biological Life Sciences. USBiological 9
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1-Ethyl-3-hydroxypiperidine 1-Ethyl-3-hydroxypiperidine acts as a reagent for the preparation of new compounds of N, N-dimethyl-[3- (1-alkylpiperidy) ]carbamates, as potential cholinesterase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 13444-24-1. Pack Sizes: 1g, 2.5g. Molecular Formula: C7H15NO, Molecular Weight: 129.199999999999. US Biological Life Sciences. USBiological 9
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1-Hydroxy Tacrine One of the impurities of Tacrine, which is an effective cholinesterase inhibitor and could probably be active in studies of Alzheimers's disease. Uses: Cholinesterase inhibitors. Synonyms: 1-Hydroxy Tacrine. Grades: > 95%. CAS No. 124027-47-0. Molecular formula: C13H14N2O. Mole weight: 214.27. BOC Sciences 7
1-Hydroxy Tacrine Maleate One of the impurities of Tacrine, which is an effective cholinesterase inhibitor and could probably be active in studies of Alzheimers's disease. Uses: Cholinesterase inhibitors. Synonyms: 1-Hydroxy Tacrine Maleate; 9-Amino-1,2,3,4-tetrahydroacridin-1-ol Maleate; 9-Amino-1,2,3,4-tetrahydro-1-acridinol (2Z)-2-Butenedioate; HP 029; Mentane; P 83-6029A; Velnacrine Hydrogen Maleate; Velnacrine Maleate. Grades: > 95%. CAS No. 118909-22-1. Molecular formula: C13H14N2O. C4H4O4. Mole weight: 330.33. BOC Sciences 7
2,3-Butanedione-2-monoxime 2,3-Butanedione-2-monoxime (BDM) is a non-selective, reversible myosin ATPase inhibitor with phosphatase-like properties. It is non-selective myosin ATPase inhibitor (Ki = 5 mM at myosin II). Uses: Cholinesterase reactivators. Synonyms: BDM; Diacetyl Monoxime; NSC 660; NSC 116103; Biacetyl monooxime. Grades: ≥95%. CAS No. 57-71-6. Molecular formula: C4H7NO2. Mole weight: 101.1. BOC Sciences 10
2,6-Dihydroxybenzaldehyde 2,6-Dihydroxybenzaldehyde is a reactant used in the synthesis of cinnamides as potent cholinesterase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 387-46-2. Pack Sizes: 1g, 2.5g, 5g. Molecular Formula: C7H6O3, Molecular Weight: 138.12. US Biological Life Sciences. USBiological 10
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(2E) -2- [ (3-Methoxyphenyl ) methy l ene ] hydrazinecar bothioamide (2E) -2- [ (3-Methoxyphenyl ) methy l ene ] hydrazinecar bothioamide used in the development of new potent and selective cholinesterase inhibitors, which might be further optimized to prevent the progression of the Alzheimer's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 1334180-01-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H11N3OS, Molecular Weight: 209.27. US Biological Life Sciences. USBiological 10
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2-Ethyl-2-methyl-1,3-dioxolane 2-Ethyl-2-methyl-1,3-dioxolane is used as a reagent in the synthesis of Strychnine Hydrochloride (S687710); a compound that acts as an antagonist for cholinesterases and beta amyloid aggregation. Also used as a reagent in the study of the prodrugs of peptide aldehyde as proteasome inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 126-39-6. Pack Sizes: 1g, 10g. Molecular Formula: C6H12O2, Molecular Weight: 116.16. US Biological Life Sciences. USBiological 10
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2-Hydroxydocosanoic acid 2-Hydroxydocosanoic acid has antioxidant, cholinesterase inhibitory, and antimicrobial activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 13980-14-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-122790. MedChemExpress MCE
(2R)-Eriodictyol (2R)-Eriodictyol is the 2R-enantiomer of Eriodictyol (E600085); used in biological studies as natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation. Eriodictyl is extracted from Yerba santa, an herb. The leaf is used to make medicine. Group: Biochemicals. Grades: Highly Purified. CAS No. 116301-03-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C15H12O6, Molecular Weight: 288.25. US Biological Life Sciences. USBiological 10
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3-(1-Azepanyl)-1-propanamine 3-(1-Azepanyl)-1-propanamine refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases. Group: Biochemicals. Grades: Highly Purified. CAS No. 3437-33-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C9H20N2. US Biological Life Sciences. USBiological 10
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3'-Methoxyacetophenone A impurity of Rivastigmine.Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: 1-(3-methoxyphenyl)ethanone. Grades: 99 %. CAS No. 586-37-8. Molecular formula: C9H10O2. Mole weight: 150.17. BOC Sciences 7
4-(1-(dimethylamino)ethyl)phenol hydrochloride An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: Dimethyl-alpha-(4-hydroxyphenyl)ethylamine hydrochloride; p-(1-(Dimethylamino)ethyl)phenol hydrochloride; Rivastigmine Impurity 11. CAS No. 1049692-05-8. Molecular formula: C10H16ClNO. Mole weight: 201.69. BOC Sciences 8
Acephate Acephate is a broad-spectrum anticholinesterase insecticide. Acephate acts via inhibiting AChE ( Cholinesterase (ChE) ) activity of insects. Acephate is used for control of several species of insects in agriculture and in horticulture [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 30560-19-1. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0841. MedChemExpress MCE
acetylsalicylate deacetylase Not identical with EC 3.1.1.1 (carboxylesterase), EC 3.1.1.2 (arylesterase), EC 3.1.1.7 (acetylcholinesterase) or EC 3.1.1.8 (cholinesterase). The activity of the liver cytosol enzyme is highest with acetyl esters of aryl alcohols, and thioesters are also hydrolysed; the microsomal enzyme also hydrolyses some other negatively charged esters, with highest activity on esters of salicylate with long-chain alcohols. Group: Enzymes. Synonyms: aspirin esterase; aspirin esterase; acetylsalicylic acid esterase; aspirin hydrolase. Enzyme Commission Number: EC 3.1.1.55. CAS No. 87348-04-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3483; acetylsalicylate deacetylase; EC 3.1.1.55; 87348-04-7; aspirin esterase; aspirin esterase; acetylsalicylic acid esterase; aspirin hydrolase. Cat No: EXWM-3483. Creative Enzymes
Acetylthiocholine bromide Acetylthiocholine bromide is a widely utilized compound in the biomedical industry, serving as a fundamental substrate to gauge cholinesterase activity. Its primary purpose is the evaluation of cholinesterase inhibition or reactivation. Synonyms: (2-Mercaptoethyl)trimethylammonium bromide acetate. CAS No. 25025-59-6. Molecular formula: C7H16BrNOS. Mole weight: 242.18. BOC Sciences
Acetylthiocholine iodide Acetylthiocholine iodide can be used as a substrate for certain enzymes, such as cholinesterase, etc., and can be used to determine the activity level of these enzymes. In addition, the compound is used in some medical research, for example in the fields of neuroscience and organ physiology. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: S-Acetylthiocholine iodide; ATCh iodide. CAS No. 1866-15-5. Pack Sizes: 10 g. Product ID: HY-D0904. MedChemExpress MCE
Acotiamide Acotiamide is a potent and seletive inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Synonyms: Acotiamide;MZ-338;UNII-D42OWK5383. CAS No. 185106-16-5. Molecular formula: C21H30N4O5S. Mole weight: 450.554. BOC Sciences
Acotiamide hydrochloride trihydrate Acotiamide, also known as YM-443 and Z-338, is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Synonyms: N-(2-(diisopropylamino)ethyl)-2-(2-hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxamide hydrochloride trihydrate; YM443; YM-443; YM 443; Z338; Z-338; Z 338; Acotiamide; Acotiamide hydrochloride trihydrate; Brand name: Acofide. Grades: 98%. CAS No. 773092-05-0. Molecular formula: C21H37ClN4O8S. Mole weight: 541.06. BOC Sciences 2
Aldicarb sulfone Aldicarb sulfone(Temik sulfone) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse. Uses: Scientific research. Group: Signaling pathways. CAS No. 1646-88-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-17530. MedChemExpress MCE
Alphachrome Alphachrome is a remarkable compound, employed in the research of the formidable Alzheimer's disease, an intricate neurodegenerative affliction. It acts as a cholinesterase inhibitor. Synonyms: Remazol brilliant blue carboxymethyl amylose. CAS No. 71501-06-9. BOC Sciences
α-NETA α-NETA is a stable, non-competitive, and slowly reversible inhibitor of choline acetyltransferase (ChAT) with IC50 value of 9 μM. It mildly inhibits cholinesterases and carnitine acetyltransferase. Synonyms: HY-124957; 2-Naphthoylethyltrimethylammonium. Grades: ≥97%. CAS No. 31059-54-8. Molecular formula: C16H20NO·I. Mole weight: 369.2. BOC Sciences 9
Altenuene (-)-Altenuene is a toxin isolated from the fungus Alternaria tenuis. It has antioxidant activity and inhibits cholinesterases. Synonyms: (2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one. Grades: >95%. CAS No. 29752-43-0. Molecular formula: C15H16O6. Mole weight: 292.29. BOC Sciences
Alternariol monomethyl ether The 50 ppm acetonitrile solution of Alternariol monomethyl ether, shows activities as a cholinesterase inhibitor as well as an anti-fungal agent, could be commonly used as a standard solution. It is an alternaria mycotoxin and genotoxin, which can inhibit the activity of DNA-topoisomerases. Synonyms: 6H-Dibenzo[b,d]pyran-6-one, 3,7(3,9 or 7,9)-dihydroxy-9(7 or 3)-methoxy-1-methyl-; 3,7(3,9 or 7,9)-Dihydroxy-9(7 or 3)-methoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one; Alternariol, methyl ether. Grades: >95%. CAS No. 26894-49-5. Molecular formula: C15H12O5. Mole weight: 272.25. BOC Sciences
Ambenonium Ambenonium is a long-acting cholinesterase inhibitor used as a treatment of myasthenia gravis. The mechanism of Ambenonium is similar to neostigmine. Synonyms: Win-8077; N,N'-[(1,2-Dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl)]bis[2-chloro-N,N-diethylbenzenemethanaminium]. CAS No. 7648-98-8. Molecular formula: C28H42Cl2N4O2. Mole weight: 537.57. BOC Sciences 2
AP2238 AP2238 is a inhibitor of both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Uses: Cholinesterase inhibitors. Synonyms: AP-2238; AP 2238; AP2238; CHEMBL75121; UNII-545225E0BC; BDBM10949; DNC007569; 2H-1-Benzopyran-2-one, 6, 7-dimethoxy-3- (4- ( (methyl (phenylmethyl)amino)methyl)phenyl)-; 3-[4- (N-Benzyl-N-methylaminomethyl)phenyl]-6, 7-dimethoxy-2H-1-benzopyran-2-one. Grades: 98%. CAS No. 553681-56-4. Molecular formula: C26H25NO4. Mole weight: 415.48. BOC Sciences 2
Asoxime Chloride Cholinesterase reactivator. A potential antidote for organophosphate poisoning. Synonyms: 1[[[4- (Aminocarbonyl) pyridinio]methoxy]methyl]-2-[ (hydroxyimino) methyl]pyridinium Dichloride. Grades: > 95%. CAS No. 34433-31-3. Molecular formula: C14H16N4O3.2 Cl. Mole weight: 359.21. BOC Sciences
Asoxime Chloride (1 [ [ [4- (Aminocarbonyl) pyridinio] methoxy] methyl] -2- [ (hydroxyimino) methyl] pyridinium Dichloride) Cholinesterase reactivator. A potential antidote for organophosphate poisoning. Group: Biochemicals. Alternative Names: 1 [ [ [4- (Aminocarbonyl) pyridinio] methoxy] methyl] -2- [ (hydroxyimino) methyl] pyridinium Dichloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
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Atropine sulfate monohydrate Atropine sulfate is a cholinergic drug that inhibits the enzyme acetylcholinesterase. It is used to treat bradycardia and to reduce the spasms of smooth muscle, including those of the bronchi, gastrointestinal tract, uterus, bladder and urinary passages. Atropine sulfate also has been used as an antidote for poisoning by organophosphates and other cholinesterase inhibitors. The drug is readily absorbed from the gastrointestinal tract, with peak plasma concentrations occurring about one hour after ingestion. The half-life is about three hours. The major route of elimination is via renal excretion of unchanged drug in urine. Group: Other alkaloids. Alternative Names: a-(Hydroxymethyl)benzeneacetic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate hydrateAtropine sulfate hydrateAtr opisol. CAS No. 5908-99-6. Molecular formula: C34H50N2O11S. Mole weight: 694.83 g/mol. Canonical SMILES: CN1[C@@H]2CC[C@H]1CC (C2)OC (=O)C (CO)C3=CC=CC=C3. CN1[C@@H]2CC[C@H]1CC (C2)OC (=O)C (CO)C3=CC=CC=C3. O. OS (=O) (=O)O. Catalog: ACM5908996-2. Alfa Chemistry.
bis(7)-Tacrine Acetylcholinesterase (AChE) is the primary cholinesterase in the body. It is an enzyme catalyzing the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. Tacrine is an amino acridine compound that inhibits acetylcholinesterase (AChE), which has been proposed as a clinical treatment for Alzheimer's disease. Bis(7)-Tacrine is a tacrine dimer, linked via a 7-carbon alkyl spacer. It inhibits AChE with an IC50 of 0.40 nM, making it more than 1,000 times more potent than tacrine. It is thought to have multiple mechanisms of action including inhibition of AChE, and inihbititon of the amyloid precursor protein/beta-amyloid cascade. It has been shown to inhibit the formation of Aβ1-42 oligomers and reduce the amount of pre-formed Aβ1-42 oligomers. Synonyms: 1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydro-acridine. Grades: ≥98%. CAS No. 224445-12-9. Molecular formula: C33H40N4·2HCl. Mole weight: 565.6. BOC Sciences 10
Carbachol (Carbamylcholine Chloride) Carbamylcholine Chloride is a cholinergic receptor agonist. Studies show that Carbamylcholine Chloride is resistant to the action of cholinesterases. Carbamylcholine Chloride also displays antiapoptotic effects in cerebellar granule neurons. Group: Biochemicals. Alternative Names: (2-Carbamoyloxyethyl) trimethylammonium Chloride; (2-Hydroxyethyl)trimethyl ammonium Chloride Carbamate; Carbachol; Carbachol Chloride; Carbacholin; Carbacholine; Carbacholine Chloride; Carbacolina; Carbaminocholine Chloride; Carbaminoylcholine Chloride; Carbamiotin; Carbamoylcholine Chloride; Carbamoylcholine-hydrochloride; Carbastat Intraocular; Carbochol; Carbocholin; Carbocholine; Carbyl; Carcholin; Choline Carbamate Chloride; Coletyl; Doryl; Doryl (pharmaceutical); Isopto Carbachol; Jestryl; Lentin; Miostat; Moryl; Vasoperif; γ-Carbamoyl Choline Chloride. Grades: Highly Purified. CAS No. 51-83-2. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences. USBiological 6
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Carbaryl Cholinesterase inhibitor. Ectoparasiticide. Group: Biochemicals. Alternative Names: 1-Naphthyl N-Methylcarbamate; 1-Naphthalenol Methylcarbamate; 1-Naphtyl N-Methylcarbamate; ENT-23969; OMS-29; UC-7744; Carylderm; Derbac; Ravyon; Sevin. Grades: Highly Purified. CAS No. 63-25-2. Pack Sizes: 1g. US Biological Life Sciences. USBiological 2
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Carbaryl-d7 (1-Naphthalenol Methylcarbamate-d7, 1-Naphtyl N-Methylcarbamate-d7,. ENT-23969-d7, OMS-29-d7, UC-7744-d7, Carylderm-d7, Derbac-d7, Ravyon-d7, Sevin-d7) Cholinesterase inhibitor. Group: Biochemicals. Alternative Names: 1-Naphthalenol Methylcarbamate-d7; 1-Naphtyl N-Methylcarbamate-d7; ENT-23969-d7; OMS-29-d7; UC-7744-d7; Carylderm-d7; Derbac-d7; Ravyon-d7; Sevin-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
(Carbethoxymethylene) triphenylphosphorane A common Wittig reagent. A cholinesterase inhibitor. Group: Biochemicals. Alternative Names: 2- (tri phenylphosphoranylide ne ) acetic Acid Ethyl Ester; (2-Ethoxy-2-oxoethylidene) triphenylphosphorane; Ethyl (tri phenylphosphoranylide ne ) acetate; NSC 72406. Grades: Highly Purified. CAS No. 1099-45-2. Pack Sizes: 50g. US Biological Life Sciences. USBiological 2
Worldwide
Carbofuran Cholinesterase inhibitor. Use as systemic insecticide, acaricide, nematocide. Group: Biochemicals. Alternative Names: 2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-Methylcarbamate; Bay 70143; NIA-10242; Furadan. Grades: Highly Purified. CAS No. 1563-66-2. Pack Sizes: 10g. US Biological Life Sciences. USBiological 2
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Carbofuran-d3 (2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-Methylcarbamate-d3, Bay 70143-d3, NIA-10242-d3, Furadan-d3) Cholinesterase inhibitor. Use as systemic insecticide, acaricide, nematocide. Group: Biochemicals. Alternative Names: 2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-Methylcarbamate-d3; Bay 70143-d3; NIA-10242-d3; Furadan-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
Chavicol Chavicol (p-Hydroxyallylbenzene, compound 6) can inhibit acetylcholinesterase ( Cholinesterase (ChE) ), with an IC 50 of 7.42 μM. Chavicol has anti-cancer activity and can suppress the growth, survival, migration, and invasion of cancer cells. Chavicol cytotoxic effect is significant, approximately 31 μg/mL in A-549 cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: p-Hydroxyallylbenzene. CAS No. 501-92-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W159754. MedChemExpress MCE
Cyclanoline chloride Cyclanoline (chloride) shows cholinesterase inhibitory activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 17472-50-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-120692. MedChemExpress MCE
Demecarium bromide Demecarium is a parasympathomimetic that acts as an acetylcholinesterase inhibitor. It is one of several topical (applied directly to the affected area) medications used to reduce elevated intraocular pressure (IOP) associated with primary glaucoma in cats, dogs, and other animals. Uses: Cholinesterase inhibitors; miotics. Synonyms: 3, 3'-[1, 10-decanediylbis[ (methylimino)carbonyloxy]]bis[N, N, N-trimethylbenzenaminium Bromide; (m-Hydroxyphenyl)trimethylammonium Bromide Decamethylenebis[methylcarbamate]; (m-hydroxyphenyl)trimethylammonium Bromide Decamethylenebis[methylcarbamate]; Demekarium Bromide; Demekastigmine Bromide; Frumtosnil; Humorsol. Grades: ≥95%. CAS No. 56-94-0. Molecular formula: White Solid. Mole weight: 716.59. BOC Sciences 9
Demecarium Bromide Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor, with an apparent affinity ( K iapp ) of 0.15 μM [1]. Demecarium Bromide (BC-48) is used as a glaucoma agent [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BC-48. CAS No. 56-94-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1626A. MedChemExpress MCE
Diazinon A cholinesterase inhibitor; a nonsystemic organophosphate insecticide. Group: Biochemicals. Alternative Names: O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate; NSC 8938; Oleodiazinon; Phosphorothioc Acid O,O-Diethyl O-[6-Methyl-2-(1-methylethyl)-4-pyrimidinyl] Ester. Grades: Highly Purified. CAS No. 333-41-5. Pack Sizes: 1g. US Biological Life Sciences. USBiological 2
Worldwide
Diazinon-d10 (Diazinon-diethyl-d10, Phosphorothioc Acid O,O-diethyl-d10 O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl]ester) Cholinesterase inhibitor. Group: Biochemicals. Alternative Names: Diazinon-diethyl-d10; Phosphorothioc Acid O,O-diethyl-d10 O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl]ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 1
Worldwide
Dichlorvos Cholinesterase inhibitor. Anthelmintic, insecticide. Group: Biochemicals. Alternative Names: Phosphoric Acid 2,2-Dichloroethenyl Dimethyl Ester; Dichlorophos; DDVP; SD-1750; Task; Vapona. Grades: Highly Purified. CAS No. 62-73-7. Pack Sizes: 500mg. US Biological Life Sciences. USBiological 2
Worldwide
Dichlorvos-d6 (Phosphoric Acid 2,2-Dichloroethenyl Dimethyl Ester-d6, Dichlorophos-d6, DDVP-d6, SD-1750-d6, Task-d6, Vapona-d6) Cholinesterase inhibitor. Anthelmintic, insecticide. Group: Biochemicals. Alternative Names: Phosphoric Acid 2,2-Dichloroethenyl Dimethyl Ester-d6; Dichlorophos-d6; DDVP-d6; SD-1750-d6; Task-d6; Vapona-d6. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
Worldwide
Donepezil Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one; (±)-E 2020; 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine; Neuripezil; Tonizep; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Aricept; HSDB 7743; HSDB7743; HSDB-7743; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Eranz; Aricept ODT; donepezilo; donepezilum; CHEMBL502; donepezil hydrochloride; donepezilium oxalate trihydrate; E 2020; E-2020; E2020; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; (RS)-2-[(1-BENZYL-PIPERIDIN-4-YL)METHYL]-5,6-DIMETHOXYINDAN-1-ONE. Grades: > 98%. CAS No. 120014-06-4. Molecular formula: C24H29NO3. Mole weight: 379.49. BOC Sciences 9
(-)-Donepezil (-)-Donepezil is one of Donepezil isomers. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Uses: Cholinesterase inhibitors; nootropic agents. Synonyms: (S)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-Inden-1-one; (2S)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one; (S)-Donepezil; (S)-Aricept; (2S)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one. Grades: ≥95%. CAS No. 142057-80-5. Molecular formula: C24H29NO3. Mole weight: 379.49. BOC Sciences 8
Doxacurium Chloride (Mixture of Diastereomers) Doxacurium Chloride is a nondepolarizing neuromuscular blocking agent that is minimally hydrolyzed by human plasma cholinesterase. Group: Biochemicals. Grades: Highly Purified. CAS No. 106819-53-8. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C56H78Cl2N2O16, Molecular Weight: 1106.13. US Biological Life Sciences. USBiological 5
Worldwide
Drofenine hydrochloride Drofenine (Cycloadiphene) hydrochloride is a potent competitive cholinesterase inhibitor with a K i value of 3 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hexahydroadiphenine hydrochloride. CAS No. 548-66-3. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B1239. MedChemExpress MCE
Ebeiedinone Ebeiedinone, a steroidal alkaloid from Fritillaria species, inhibits the bioactivity of human whole blood cholinesterase ( ChE ) at the concentration of 0.1 mM, with the inhibitory effects of 69.0% [1]. Uses: Scientific research. Group: Natural products. CAS No. 25650-68-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107275. MedChemExpress MCE
Ecothiophate iodide Ecothiophate iodide is a potent, long-acting cholinesterase inhibitor. It covalently binds by its phosphate group to serine group at the active site of the cholinesterase. It binds irreversibly to cholinesterase. It is used as an ocular antihypertensive in the treatment of chronic glaucoma and accommodative esotropia in some cases. It is also an anticholinesterase drug and used as a miotic. It has been listed. Uses: Ecothiophate iodide is used as an ocular antihypertensive in the treatment of chronic glaucoma and accommodative esotropia in some cases. it is also an anticholinesterase drug and used as a miotic. Synonyms: 2-[ (Diethoxyphosphinyl) thio]ethanaminium iodide; Phospholine iodide; N- (2- (Diethoxyphosphinylthio) ethyl) trimethylammonium iodide; Ethanaminium, 2-((diethoxyphosphinyl)thio)-N,N,N-trimethyl-, iodide. Grades: 98%. CAS No. 513-10-0. Molecular formula: C9H23INO3PS. Mole weight: 383.23. BOC Sciences 11
Eriodictyol Eriodictyol is a flavanone characteristic of lime, found mainly in juice. The glycosylated forms are eriocitrin (bound to a rutinoside) and neoeriocitrin (bound to a neohesperidose). Eriodictyol prevents some secondary effects of diabetes, such as diabetic retinopathy and biochemical changes in plasma (study in rats) (Bucolo et al., 2012). In addition, it has been reported that in in vitro studies, eriodictyol decreases insulin resistance and glucose absorption.Eriodictyol is used in biological studies as natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation. Eriodictyl is extracted from Yerba santa, an herb. The leaf is used to make medicine.Yerba santa is used for respiratory conditions including coughs, colds, tuberculosis, asthma, and chronic bronchitis. It is also used for fever and dry mouth. Some people use it to relieve muscle spasms, to loosen phlegm, and as a tonic. Group: Biochemicals. Alternative Names: (2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one; (2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one; 3',4',5,7-tetrahydroxy-flavanone; (+)-Eriodictyol; (2S)-Eriodictyol; (S)-3',4',5,7-Tetrahydroxyflavanone; 3',4',5,7-Tetrahydroxyflavanone; Huazhongilexone. Grades: Highly Purified. CAS No. 552-58-9. Pack Sizes: 10mg, 20mg, 50mg, 100mg. Molecular Formula: C15H12O6, Molecular Weight: 288.25. US Biological Life Sciences. USBiological 8
Worldwide
Ethyl diethylcarbamate Ethyl diethylcarbamate, a carbamate derivative, finds extensive use as an alcohol denaturant and as an intermediate for the production of pesticides and pharmaceuticals. Furthermore, it exhibits potential therapeutic effects as a cholinesterase inhibitor, offering respite in the management of myasthenia gravis, a neuromuscular disorder that is typified by muscle weakness and fatigue. Synonyms: Diethyl urethane; Diethylcarbamic acid ethyl ester; Carbamic acid, N,N-diethyl-, ethyl ester; NSC 24699; N,N-diethyl O-ethylcarbamate. CAS No. 3553-80-8. Molecular formula: C7H15NO2. Mole weight: 145.20. BOC Sciences 9
Ethyl (triphenylphosphoranylidene)acetate A common Wittig reagent. A cholinesterase inhibitor. Group: Other phosphine ligands. Alternative Names: (Carbethoxymethylene) Triphenylphosphorane; Triphenylcarbethoxy methyl enephosphorane. CAS No. 1099-45-2. Molecular formula: C22H21O2P. Mole weight: 348.37. Appearance: Solid. Purity: 0.97. IUPACName: ethyl 2-(triphenyl-lambda5-phosphanylidene)acetate. Canonical SMILES: CCOC (=O)C=P (C1=CC=CC=C1) (C2=CC=CC=C2)C3=CC=CC=C3. Density: 1.086 g/cm3. ECNumber: 214-151-7. Catalog: ACM1099452-1. Alfa Chemistry. 2
Ethyl triphenylphosphoranylidene acetate Ethyl triphenylphosphoranylidene acetate is a Horner-Wittig reagent generally used in Horner-Wadsworth-Emmons (HWE) reaction. It may act as an inhibitor of cholinesterase that inhibits AChE and BChE. Synonyms: (Carbethoxymethylene) triphenylphosphorane; Triphenylcarbethoxy methyl enephosphorane; Ethyl 2-(triphenylphosphoranylidene)acetate. Grades: ≥ 95 %. CAS No. 1099-45-2. Molecular formula: C22H21O2P. Mole weight: 348.37. BOC Sciences 10
Fenitrothion Fenitrothion, one of the most widely used organophosphorus pesticides, is a cholinesterase inhibiting insecticide/acaricid. Fenitrothion is widely used, as a broad-spectrum insecticide, on cotton crops, vegetables crops, fruit crops, and field crops especially paddy. Fenitrothion leads to accumulation of nitrophenols [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122-14-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-B1885. MedChemExpress MCE
Flavonol Flavonol is a cholinesterase ( ChE ) inhibitor, with an IC 50 value of 120 μM and a K i value of 74 μM. Flavonol has antioxidant, free radical-scavenging, antibacterial properties, and immune modulation functions. Flavonol inhibits the PriA helicase of Staphylococcus aureus. Flavonol can suppress the production of NO in LPS-activated RAW 264.7 cells by inhibiting the expression of the iNOS enzyme. Flavonol shows protective and analgesic effects in mice through various neuronal pathways. Flavonol can be used in research related to tumors and atherosclerosis diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 577-85-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-107825. MedChemExpress MCE
Fustin Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) is a potent amyloid β (Aβ) inhibitor. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases the expression of acetylcholine (ACh) levels, choline acetyltransferase (ChAT) activity, and ChAT gene induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) decreases in acetyl cholinesterase (AChE) activity and AChE gene expression induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases muscarinic M1 receptor gene expression and muscarinic M1 receptor binding activity. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) can be used for Alzheimer's disease research [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone. CAS No. 20725-03-5. Pack Sizes: 1 mg. Product ID: HY-N8376. MedChemExpress MCE
Galantaminone Galantamine is a competitive and reversible cholinesterase(AChE) inhibitor, which is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments. Synonyms: (-)-Narwedine; Narwedin. Grades: >98%. CAS No. 510-77-0. Molecular formula: C17H19NO3. Mole weight: 285.34. BOC Sciences 8
Galanthamine Galanthamine, also called Razadyne, found in GALANTHUS and other AMARYLLIDACEAE, a cholinesterase inhibitor prescribed to treat symptoms of mild to moderate Alzheimer's, enhances cholinergic function accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Uses: Treatment of alzheimer's disease. Synonyms: NSC 100058; NSC100058; NSC-100058; BRN 0093736; BRN0093736; BRN-0093736; Galantamine; Reminyl; Lycoremine; (-)-Galanthamine; Galantamin; Lycoremin; Jilkon; Nivalin; Razadyne; Galantamina; Galanthaminum; Galantaminum; Razadyne ER; Galantaminum. Grades: >98%. CAS No. 357-70-0. Molecular formula: C17H21NO3. Mole weight: 287.35. BOC Sciences 10

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