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CMK is a RSK2 kinase inhibitor. Its IC50 value for Cdc5(L158G) is 36 nM. It is used in the preparation of serine/threonine kinase inhibitors. Uses: Cmk is used in the preparation of serine/threonine kinase inhibitors. Synonyms: 1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone. Grades: 95%. CAS No. 821794-90-5. Molecular formula: C18H19ClN4O2. Mole weight: 358.82.
CMK
CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK. Uses: Scientific research. Group: Signaling pathways. CAS No. 821794-90-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-52101.
CMK-3
CMK-3. Uses: Designed for use in research and industrial production. Product Category: Mesoporous Carbon and Carbon Nanomaterials. CAS No. 7440-44-0. Product ID: ACM7440440-216. Alfa Chemistry ISO 9001:2015 Certified. Categories: methane, CM-32 armoured vehicle.
CMK-8
CMK-8. Uses: Designed for use in research and industrial production. Product Category: Mesoporous Carbon and Carbon Nanomaterials. CAS No. 7440-44-0. Product ID: ACM7440440-161. Alfa Chemistry ISO 9001:2015 Certified. Categories: CMA 8.
AAF-CMK trifluoroacetate salt
AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome function, and reversibly inhibits Cln2 (TPPI). Synonyms: N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase Inhibitor II; L-Alaninamide,L-alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-. Grades: ≥95%. CAS No. 184901-82-4. Molecular formula: C18H23ClF3N3O5. Mole weight: 453.84.
Ac-DEVD-CMK
Ac-DEVD-CMK is a cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, -7, -8, and -10. It is commonly used at concentrations up to 100 μM to examine the role of caspase-3-dependent apoptosis in biological systems. Synonyms: Ac-Asp-Glu-Val-Asp-chloromethylketone; Caspase-3 Inhibitor III; N-acetyl-Asp-Glu-Val-Asp-chloromethylketone; N-Acetyl-L-α-aspartyl-L-α-glutamyl-N-[(2S)-1-carboxy-4-chloro-3-oxo-2-butanyl]-L-valinamide; (2S,5S,8S,11S)-8-(2-carboxyethyl)-11-(carboxymethyl)-2-(2-chloroacetyl)-5-isopropyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecane-1-carboxylic acid. Grades: ≥98%. CAS No. 285570-60-7. Molecular formula: C21H31ClN4O11. Mole weight: 550.95.
Ac-FLTD-CMK
Ac-FLTD-CMK is a potent and selective inhibitor of caspases 1, 5 and 4 (IC50 values=46.7 nM, 0.33 μM, 1.49 μM, respectively) that inhibits gasdermin D (GSDMD) cleavage. Synonyms: N-acetyl-Phe-Leu-Thr-Asp-chloromethylketone. Grades: >95%. CAS No. 2376255-48-8. Molecular formula: C26H37ClN4O8. Mole weight: 569.05.
Ac-YVAD-CMK is a selective, irreversible inhibitor of interleukin-1β converting enzyme (ICE; Caspase-1). Ac-YVAD-CMK is neuroprotective in a rat model of cerebral ischemia. Uses: Cysteine proteinase inhibitors. Synonyms: Caspase 1 Inhibitor II. Grades: ≥98%. CAS No. 178603-78-6. Molecular formula: C24H33ClN4O8. Mole weight: 541.
Decanoyl-RVKR-CMK. Group: Biochemicals. Grades: Purified. CAS No. 150113-99-8. Pack Sizes: 1mg. US Biological Life Sciences.
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Decanoyl-RVKR-CMK
Decanoyl-RVKR-CMK is a proprotein convertase inhibitor and has been found to restrain regulated secretion of the neuronal polypeptide VGF in PC12 cells. Synonyms: Decanoyl-Arg-Val-Lys-Arg-CMK; N2-(1-Oxodecyl)-L-arginyl-L-valyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-L-lysinamide. Grades: >98%. CAS No. 150113-99-8. Molecular formula: C34H66ClN11O5. Mole weight: 744.42.
A potent and irreversible inhibitor of Urokinase (uPA (IC50<1uM), Factor VIIa, Factor IXa, Factor Xa, and trypsin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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H-Ile-CMK·HCl
H-Ile-CMK·HCl. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
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H-Ile-CMK·HCl ≥95% (NMR)
H-Ile-CMK·HCl ≥95% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Nitrogen doped CMK-3. Uses: Designed for use in research and industrial production. Product Category: Mesoporous Carbon and Carbon Nanomaterials. CAS No. 7440-44-0. Product ID: ACM7440440-109. Alfa Chemistry ISO 9001:2015 Certified. Categories: methane.
A highly potent, selective and irreversible thrombin inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 142036-63-3. Pack Sizes: 5mg. US Biological Life Sciences.
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Z-DEVD-CMK trifluoroacetate salt
Z-DEVD-CMK is a protease inhibitor.that irreversibly inhibits recombinant caspase-3, cathepsin B, cathepsin L, cathepsin V, cathepsin F, and cathepsin S in enzyme assays. Grades: ≥95%. Molecular formula: C27H35ClN4O12·xCF3COOH. Mole weight: 643.04.
Z-YVAD-CMK is an inhibitor of caspase-1 and caspase-3. It exhibits anti-apoptotic, anti-inflammatory and neuroprotective effects. Synonyms: Benxyloxycarbonyl-Tyr-Val-Ala-Asp-Chloromethylketone; Caspase-1 Inhibitor IV. Grades: ≥95%. Molecular formula: C30H37ClN4O9·xCF3COOH. Mole weight: 633.09.
Boc-L-Valine chloromethyl ketone. Group: Biochemicals. Alternative Names: Boc-L-Val-CMK. Grades: Highly Purified. CAS No. 103542-47-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
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Boc-L-Valine chloromethyl ketone
Synonyms: Boc-L-Val-CMK; Boc-L-Valine chloromethyl ketone; Boc-Val CH2Cl; Boc-Val-CMK; Boc Val CMK; (S)-tert-Butyl (1-chloro-4-methyl-2-oxopentan-3-yl)carbamate; tert-Butyl [(3S)-1-chloro-4-methyl-2-oxopentan-3-yl]carbamate; tert-butyl N-[(3S)-1-chloro-4-methyl-2-oxopentan-3-yl]carbamate; Boc L Val CMK. Grades: ≥ 98% (HPLC). CAS No. 103542-47-8. Molecular formula: C11H20NO3Cl. Mole weight: 249.73.
Carboxymethyl Konjac
CMK. Product ID: 5-00946.
Caspase-9 Inhibitor III
Caspase-9 Inhibitor III (Ac-LEHD-cmk) is a caspase-9 inhibitor. Caspase-9 Inhibitor III exhibits protective effects on ischemia-reperfusion-induced myocardial injury [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ac-LEHD-cmk. CAS No. 403848-57-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136744.
Caspase-9 Inhibitor III
Caspase-9 Inhibitor III is a potent and irreversible inhibitor of caspase-9 with cardioprotective effects. Caspase inhibitors play an important role in investigating biological processes. Caspase-9 can reduce infarct size, lactate dehydrogenase (LDH) and creatine kinase (CK) release, and DNA smearing induced by ischemia and reperfusion in isolated rat hearts. The caspase family of proteins function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Synonyms: Ac-LEHD-CMK. Grades: 98%. CAS No. 403848-57-7. Molecular formula: C24H35ClN6O9. Mole weight: 587.02.
Cyclohexanethiol
Cyclohexanethiol appears as a colorless liquid with a strong disagreeable odor. Insoluble in water and less dense than water. Vapors heavier than air. Flash point near 50°F.;COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR.;Colorless liquid with a strong, offensive odor. Group: Self-assembly materials self assembly and contact printing materials. CAS No. 1569-69-3. Product ID: cyclohexanethiol. Molecular formula: 116.23g/mol. Mole weight: C6H11SH;C6H12S. C1CCC(CC1)S. InChI=1S / C6H12S / c7-6-4-2-1-3-5-6 / h6-7H, 1-5H2. CMKBCTPCXZNQKX-UHFFFAOYSA-N.
Dphe-phe-arg-chloromethylketone
Dphe-phe-arg-chloromethylketone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: phenylalanyl-phenylalanyl-argininechloromethylketone;DPHE-PHE-ARG-CHLOROMETHYLKETONE;DPHE-PHE-ARG-CMK;H-D-PHE-PHE-ARG-CHLOROMETHYLKETONE TRIFLUOROACETATE SALT;H-D-PHE-PHE-ARG-CMK TFA;PPACK II, TRIFLUOROACETATE SALT;H-D-Phe-Phe-Arg-chloromethylketone;D-Ph. Product Category: Heterocyclic Organic Compound. Appearance: Off-White Solid. CAS No. 74392-49-7. Molecular formula: C25H33ClN6O3. Mole weight: 501.02. Purity: 0.96. IUPACName: (2R)-2-amino-N-[(2S)-2-[[(3S)-1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]-3-phenylpropanoyl]-3-phenylpropanamide. Canonical SMILES: C1=CC=C(C=C1)CC(C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)CCl)N. Density: 1.308g/cm³. Product ID: ACM74392497. Alfa Chemistry ISO 9001:2015 Certified.
D-Phe-phe-arg chloromethylketone trifluoroacetate salt
D-Phe-phe-arg chloromethylketone trifluoroacetate salt. Group: Biochemicals. Alternative Names: DPHE-PHE-ARG-CMK; D-Phenylalanyl-N-[ (1S) -4-[ (aminoiminomethyl) amino]-1- (2-chloroacetyl) butyl]-L-phenylalaninamide. Grades: Highly Purified. CAS No. 74392-49-7. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C27H34ClF3N6O5. US Biological Life Sciences.
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D-Phe-Phe-Arg Chloromethylketone Trifluoroacetic Acid Salt
D-Phe-Phe-Arg Chloromethylketone Trifluoroacetic Acid Salt. Group: Biochemicals. Alternative Names: DPHE-PHE-ARG-CMK Trifluoroacetic Acid Salt; D-Phenylalanyl-N-[ (1S) -4-[ (aminoiminomethyl) amino]-1- (2-chloroacetyl) butyl]-L-phenylalaninamide Trifluoroacetic Acid Salt. Grades: Highly Purified. CAS No. 74392-49-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
H-D-Phe-Pro-Arg-chloromethylketone is a highly effective and irreversible inhibitor of thrombin and gingipain R. Synonyms: PPACK; H-D-Phe-Pro-Arg-CH2Cl; fPR-CMK; D-phenylalanine-proline-arginine methyl chloride; D-Phe-Pro-Age-CMK; (S)-1-((R)-2-amino-3-phenylpropanoyl)-N-((S)-1-chloro-6-guanidino-2-oxohexan-3-yl)pyrrolidine-2-carboxamide; (S)-1-(D-phenylalanyl)-N-((S)-1-chloro-6-guanidino-2-oxohexan-3-yl)pyrrolidine-2-carboxamide; D-Phe-pro-arg-methyl chloride; D-Phenylalanyl-N-{(3S)-1-chloro-6-[(diaminomethylene)amino]-2-oxo-3-hexanyl}-L-prolinamide. Grades: ≥95% by HPLC. CAS No. 71142-71-7. Molecular formula: C21H31ClN6O3. Mole weight: 450.97.
L-Leucine chloromethyl ketone hydrochloride
L-Leucine chloromethyl ketone hydrochloride. Group: Biochemicals. Alternative Names: L-Leu-CMK·HCl. Grades: Highly Purified. CAS No. 54518-92-2. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
An inhibitor of gramicidin S synthetase 2. Synonyms: L-Phenylalanine chloromethylketone hydrochloride; PHENYLALANINE-CHLOROMETHYLKETONE HCl; L-PHENYLALANINE CHLOROMETHYLKETONE HYDROCHLORIDE; H-PHE-CHLOROMETHYLKETONE HCl; H-PHE-CMK HCl. Grades: ≥ 99% (NMR). CAS No. 52735-71-4. Molecular formula: C10H12NOCl·HCl. Mole weight: 234.19.
L-Phenylalanine chloromethylketone hydrochloride
L-Phenylalanine chloromethylketone hydrochloride. Group: Biochemicals. Alternative Names: L-Phe-CMK·HCl. Grades: Highly Purified. CAS No. 52735-71-4. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
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L-Valine chloromethyl ketone hydrochloride
L-Valine chloromethyl ketone hydrochloride acts as a reagent in the preparation of tetrapeptidyl chloromethyl ketones, which are potent inhibitors of proteinase K. Synonyms: L-Val-CMK HCl; H-Val CH2Cl HCl; H-L-Val-CMK HCl; (3S)-3-amino-1-chloro-4-methylpentan-2-one hydrochloride; L Val CMK HCl; H L Val CMK HCl. Grades: ≥ 97%. CAS No. 107831-79-8. Molecular formula: C6H12ClNO·HCl. Mole weight: 186.10.
L-Valine chloromethyl ketone hydrochloride
L-Valine chloromethyl ketone hydrochloride. Group: Biochemicals. Alternative Names: L-Val-CMK·HCl. Grades: Highly Purified. CAS No. 107831-79-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
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Meosuc-ala-ala-pro-ala-chloromethylketone
Meosuc-ala-ala-pro-ala-chloromethylketone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: methoxysuccinyl-alanyl-alanyl-prolyl-alaninechloromethylketone;MEOSUC-AAPA-CMK;MEOSUC-ALA-ALA-PRO-ALA-CHLOROMETHYLKETONE;MEOSUC-ALA-ALA-PRO-ALA-CMK;ELASTASE INHIBITOR II;HNE INHIBITOR;MSACK. Product Category: Heterocyclic Organic Compound. CAS No. 111682-13-4. Molecular formula: C20H31ClN4O7. Mole weight: 474.94. Product ID: ACM111682134. Alfa Chemistry ISO 9001:2015 Certified.