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Cyclosporin is a cyclic decapeptide that could be isolated form the soil fungi Tolypocladium inflatum. Cyclosporin is an immunosuppressant thought to bind to cyclophilin in T-lymphocytes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79217-60-0. Pack Sizes: 25 mg; 50 mg. Product ID: HY-100731.
Cyclosporin
It is produced by the strain of Polypocladiurn inflatum. It has a strong immunosuppressive action, but also has anti-inflammatory and weak antifungal effects. The mechanism of immunosuppression is the combination of cyclosporin A and cyclosporin-binding protein in T cells, which inhibits the activity of Calcineurin, and then impedes the transposition of intracellular transcription factors into the nucleus, and inhibits the interleukin-2 transcription, resulting in immunosuppression. It is mainly used for kidney transplantation, bone marrow and heart transplantation, and is one of the most important immunosuppressive agents in clinical application. Uses: Enzyme inhibitors. Synonyms: Restasis; Cyclosporine; Gengraf; Sandimmune; SangCyA; Atopica. Grades: >98%. CAS No. 79217-60-0. Molecular formula: C62H111N11O12. Mole weight: 1202.61.
Cyclosporin A
100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C62H111N11O12. CAS No. 59865-13-3. Prepack ID 40007313-100mg. Molecular Weight 1202.61. See USA prepack pricing.
Cyclosporin A
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C62H111N11O12. CAS No. 59865-13-3. Prepack ID 40007313-1g. Molecular Weight 1202.61. See USA prepack pricing.
Cyclosporin A
Cyclosporin A (Cyclosporine A) is an immunosuppressant that binds to cyclophilins, inhibiting calcineurin activity with an IC50 of 7 nM. It also inhibits CD11a/CD18 adhesion molecules. Synonyms: Ciclosporin; cyclosporine; Cyclosporine A; Sandimmun; Cyclosporin; Neoral; Ciclosporine; Sandimmune; Ramihyphin A. Grades: 98%. CAS No. 59865-13-3. Molecular formula: C62H111N11O12. Mole weight: 1202.61.
Cyclosporin A
Potent immunosuppressant (same as FK-506 and rapamycin). Forms a complex with cyclophilin. Inhibits the activity of the calcium/calmodulin-dependent protein phos- phatase 2B (PP2B; calcineurin). Prevents the dephosphorylation of nuclear factor of activated T cells (NFAT) transcription factor, leading to disruption of T cell activation. Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 (IL-2). Prevents rejection of transplanted organs. Anti-inflammatory compound in the treatment of several inflammatory skin diseases (e.g. atopic dermatitis) and with potential anti-rheumatic activity (rheumatoid arthritis). Antibacterial. Antifungal. Antiparasitic. Apoptosis inhibitor. Inhibits the mitochondrial permeability transition pore (MPTP) from opening, thus inhibiting cytochrome c release. NF-kappaB suppressor by induction of unfolded protein response (UPR). Anti-cancer compound. Apoptosis and autophagy inducer. Inhibits n Group: Biochemicals. Alternative Names: Antibiotic S 7481F1; Ciclosporin A; CsA; Cyclosporine; NSC 290193; Ramihyphin A; Sandimmun; Sandimmune; Neoral; Optimmune; Restasis; OL 27-400. Grades: Highly Purified. CAS No. 59865-13-3. Pack Sizes: 5g, 10g. US Biological Life Sciences.
Worldwide
Cyclosporin A-13C2,d4 Acetate
Labeled Cyclosporin A derivative. An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity. Group: Biochemicals. Alternative Names: Cyclosporine-13C2,d4 Acetate; Ciclosporin-13C2,d4 Acetate; Atopica-13C2,d4 Acetate; Sandimmun(e)-13C2,d4 Acetate; Neoral-13C2,d4 Acetate; Optimmune-13C2,d4 Acetate; Restasis-13C2,d4 Acetate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-13C2,d4 (Major).
An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Group: Biochemicals. Alternative Names: Cyclosporine-13C2,d4; Ciclosporin-13C2,d4; Atopica-13C2,d4; Sandimmun(e)-13C2,d4; Neoral-13C2,d4; Optimmune-13C2,d4; Restasis-13C2,d4. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Cyclosporin A 8-N-MeAla
Cyclosporin A 8-N-MeAla. Uses: For analytical and research use. Group: Impurity standards. CAS No. 108466-41-7. Molecular Formula: C63H113N11O12. Mole Weight: 1216.66. Catalog: APB108466417.
Cyclosporin A, 9-(N-methyl-L-Isoleu)
Cyclosporin A, 9-(N-methyl-L-Isoleu). Uses: For analytical and research use. Group: Impurity standards. CAS No. 143205-42-9. Molecular Formula: C62H111N11O12. Mole Weight: 1202.64. Catalog: APB143205429.
Cyclosporin A, 9-(N-methyl-L-valine)
Cyclosporin A, 9-(N-methyl-L-valine). Uses: For analytical and research use. Group: Impurity standards. CAS No. 156047-28-8. Molecular Formula: C61H109N11O12. Mole Weight: 1188.61. Catalog: APB156047288.
Cyclosporin A Acetate
A non-immunosuppressive analog. Group: Biochemicals. Alternative Names: 6-[(2S,3R,4R,6E)-3-(Acetyloxy)-4-methyl-2-(methylamino)-6-octenoic acid] Cyclosporin A; B 3-243; O-Acetyl-C91-cyclosporin A; O-Acetylcyclosporin A; SDZ 33-243. Grades: Highly Purified. CAS No. 83602-41-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-d4 Acetate (Major)
A non-immunosuppressive analog. Group: Biochemicals. Alternative Names: 6-[(2S,3R,4R,6E)-3-(Acetyloxy)-4-methyl-2-(methylamino)-6-octenoic-d4 acid] Cyclosporin A; B 3-243-d4; O-Acetyl-C91-cyclosporin A-d4; O-Acetylcyclosporin A-d4; SDZ 33-243-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-d4 (Major)
An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Group: Biochemicals. Alternative Names: Cyclosporine-d4; Ciclosporin-d4; Atopica-d4; Sandimmun(e)-d4; Neoral-d4; Optimmune-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-Derivative 1
Cyclosporin A-Derivative 1 is a metabolite of cyclosporine A. Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin phosphatase. Synonyms: Leu-Val-Leu-Ala-D-Ala-Leu-Leu-Val-Aaa-Abu-Sar.BF4; (7S, 10S, 13S, 16S, 19S, 22R, 25S, 28S, 31S, 34S)-10-[(1R, 2R, 4E)-1-Acetoxy-2-methyl-4-hexen-1-yl]-7-ethyl-16, 19, 28-triisobutyl-13, 31-diisopropyl-N, 5, 11, 14, 17, 20, 22, 25, 29, 36-decamethyl-3, 6, 9, 12, 15, 18, 21, 24, 27, 3 0,33-undecaoxo-2-oxa-5,8,11,14,17,20,23,26,29,32-decaazaheptatriacontan-34-aminium tetrafluoroborate. Grades: ≥98%. CAS No. 1487360-85-9. Molecular formula: C65H118BF4N11O14. Mole weight: 1364.50.
Cyclosporin A-Derivative 1 Free base
Cyclosporin A-Derivative 1 Free base is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporin A open ring; N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester; Cyclosporin A-Derivative 1 (Free base); Cyclosporin A seco(MeGly-MeLeu) Methyl Ester; Leu-Val-Leu-Ala-{d-Ala}-Leu-Leu-Val-{Aaa}-{Abu}-{Sar}; LVLA-{d-Ala}-LLV-{Aaa}-{Abu}-{Sar}. Grades: ≥95%. CAS No. 286852-20-8. Molecular formula: C65H117N11O14. Mole weight: 1276.69.
Cyclosporin A Isomer
Cyclosporin A Isomer. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59865-16-6. Molecular Formula: C62H111N11O12. Mole Weight: 1202.64. Catalog: APB59865166.
Cyclosporin AM 1
A cyclosporine metabolite specifically inhibits growth of renal cells in culture. Group: Biochemicals. Alternative Names: 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin A; Cyclosporin A Metabolite 17; Cyclosporin Metabolite 17; M 17; OL 17. Grades: Highly Purified. CAS No. 89270-28-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin AM 1
Cyclosporin AM 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 89270-28-0. Molecular Formula: C62H111N11O13. Mole Weight: 1218.63. Catalog: APB89270280.
Cyclosporin AM 3
Cyclosporin AM 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153049-50-4. Molecular Formula: C62H111N11O13. Mole Weight: 1218.63. Catalog: APB153049504.
Cyclosporin AM 4
Cyclosporin AM 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 89270-23-5. Molecular Formula: C61H109N11O12. Mole Weight: 1188.61. Catalog: APB89270235.
Cyclosporin AM 4N
Cyclosporin AM 4N is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 9-L-Leucinecyclosporin A; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane Cyclic Peptide Deriv; AM 4N; Cyclosporin A Metabolite 21; M 21; OL 21; [Leu4]cyclosporin. Grades: ≥90% by HPLC. CAS No. 89270-23-5. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin AM 6
Cyclosporin AM 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 154334-72-2. Molecular Formula: C59H107N11O12. Mole Weight: 1162.57. Catalog: APB154334722.
Cyclosporin AM 7
Cyclosporin AM 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132362-39-1. Molecular Formula: C61H109N11O13. Mole Weight: 1204.61. Catalog: APB132362391.
Cyclosporin AM 9
Cyclosporin AM 9 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (4-Hydroxy-N-methyl-L-leucine)cyclosporine; 3-(4-Hydroxy-N-methyl-L-leucine)cyclosporin A; Cyclosporin A Metabolite 1; AM 9 (Peptide); OL 1; Cyclosporine metabolite M1; Cyclosporin metabolite AM9; Cyclosporine metabolite AM9; Cyclosporin A metabolite M1; (gamma-OH)MeLeu-9-cyclosporin; (gamma-OH)MeLeu-9-cyclosporine; (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-4-hydroxy-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-). Grades: ≥90% by HPLC. CAS No. 89270-25-7. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
Cyclosporin AM 9
Cyclosporin AM 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 89270-25-7. Molecular Formula: C62H111N11O13. Mole Weight: 1218.63. Catalog: APB89270257.
cyclosporin A, MeAla(6)-
cyclosporin A, MeAla(6)-. CAS No. 111710-61-3. Catalog: ACM111710613.
Cyclosporin A (Standard)
Cyclosporin A (Standard) is the analytical standard of Cyclosporin A. This product is intended for research and analytical applications. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM [3]. Cyclosporin A also inhibits CD11a/CD18 adhesion [8]. Uses: Scientific research. Group: Natural products. CAS No. 59865-13-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0579R.
Cyclosporin a sulfate
Heterocyclic Organic Compound. Alternative Names: Cyclosporin A Hydrogen Sulfate (ester). CAS No. 121673-00-5. Molecular formula: C62H111N11O15S. Mole weight: 1282.67. Purity: 0.96. Catalog: ACM121673005.
Cyclosporin A sulfate
Cyclosporin A sulfate. Group: Biochemicals. Alternative Names: Cyclosporin A hydrogen sulfate (ester). Grades: Highly Purified. CAS No. 121673-00-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C62H111N11O15S. US Biological Life Sciences.
Worldwide
Cyclosporin B
An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Group: Biochemicals. Alternative Names: Ala2-cyclosporine; Antibiotic S 7481F2. Grades: Highly Purified. CAS No. 63775-95-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cyclosporin B
Cyclosporin B is a group of nonpolar cyclic oligopeptides with immunosuppressive activity. Cyclosporin B is used for the prevention of graft rejection in organ transplantation [1]. Uses: Scientific research. Group: Peptides. CAS No. 63775-95-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1973.
Cyclosporin C
A group of nonpolar cyclic oligopeptides with immunosupppressant activity. Group: Biochemicals. Alternative Names: Thr2-cyclosporine. Grades: Highly Purified. CAS No. 59787-61-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cyclosporin C
Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal , antiviral, and immunosuppressant properties. Cyclosporin C is active against isolates of B. cinerea , A. niger , and Alternaria , Mucor , and Penicillium species (MICs=0.1-5 μg/ml). Uses: Scientific research. Group: Signaling pathways. CAS No. 59787-61-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6027.
Cyclosporin D
Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A [1] [2]. Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) [3]. Uses: Scientific research. Group: Peptides. CAS No. 63775-96-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W019721.
The pharmacological profiles of two new derivatives of the immunosuppressive drug, cyclosporine, is presented here. (Nva2)-CS has very similar properties to CS, but lacks the nephrotoxic side-effects. This derivative appears to be a potential successor to cyclosporine. (Val2)DH-CS seems to have a different spectrum of activities. It does not suppress humoral immunity and allograft rejection, but suppresses some types of cell-mediated immune responses. This derivative may prove useful in autoimmune situations where T cells are involved in the disease process. Group: Biochemicals. Alternative Names: Val2-cyclosporine, Cyclosporin D, Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl. Grades: Highly Purified. CAS No. 63775-96-2. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C63H113N11O12, Molecular Weight: 1216.64. US Biological Life Sciences.
Worldwide
Cyclosporine
Cyclosporine is an immunopsupressent thought to bind to cyclophilin in T-lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 79217-60-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C62H111N11O12, Molecular Weight: 1202.60999999999. US Biological Life Sciences.
Worldwide
Cyclosporin E
Cyclosporin E is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporin A, 5-L-valine-; Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl); 5-L-Valinecyclosporin A; (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-L-Val-). Grades: ≥90% by HPLC. CAS No. 63798-73-2. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin E
Cyclosporin E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 63798-73-2. Molecular Formula: C61H109N11O12. Mole Weight: 1188.61. Catalog: APB63798732.
Cyclosporine A
Cyclosporine A. CAS No: 59865-13-3
Sarchem Laboratories New Jersey NJ
Cyclosporine B
Cyclosporine B. Group: Biochemicals. Alternative Names: Cyclosporin B, Ala2-cyclosporine, Antibiotic S 7481F2. Grades: Highly Purified. CAS No. 63775-95-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C61H109N11O12. US Biological Life Sciences.
Worldwide
Cyclosporine C
Cyclosporine C. Group: Biochemicals. Alternative Names: Cyclosporin C, Thr2-cyclosporine. Grades: Highly Purified. CAS No. 59787-61-0. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C62H111N11O13. US Biological Life Sciences.
Worldwide
Cyclosporine EP Impurity B
Cyclosporine EP Impurity B is a closely related co-metabolite of cyclosporin A. It has no immunosuppressive activity and has been used as a control to determine the role of immunosuppression in cyclosporin A pharmacology, especially in the treatment of parasitic infections. Synonyms: Dihydrocyclosporin A; 6-[(2S,3R,4R)-3-Hydroxy-4-methyl-2-(methylamino)octanoic acid]cyclosporin A. Grades: ≥90% by HPLC. CAS No. 59865-15-5. Molecular formula: C62H113N11O12. Mole weight: 1204.62.
Cyclosporine EP Impurity C
A rearranged degradation product formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions. Synonyms: Isocyclosporin A; Iso Cyclosporin A; Ciclosporin EP Impurity C; (2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valine (11?1)-Lactone; Iso Cyclosporin A; Cyclo[L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-[(3R,4R)-3-hydroxy-N-methyl-5-[(E)-1-propenyl]-L-Leu-]]. Grades: ≥90% by HPLC. CAS No. 59865-16-6. Molecular formula: C62H111N11O12. Mole weight: 1202.61.
Cyclosporine Impurity 3 Sodium Salt
Cyclosporine Impurity 3 Sodium Salt is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Grades: ≥90% by HPLC. Molecular formula: C7H14NO3Na. Mole weight: 183.18.
Cyclosporine metabolite M17
Cyclosporine metabolite M17 is a metabolite of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Uses: A cyclosporine metabolite specifically inhibits growth of renal cells in culture. Synonyms: Cyclosporin AM 1; 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin A; Cyclosporin A Metabolite M17; Cyclosporin metabolite AM1; OL-17; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 33-[(1R,2R,4E)-1,6-dihydroxy-2-methyl-4-hexen-1-yl]-30-ethyl-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S, 6S, 9S, 12R, 15S, 18S, 21S, 24S, 30S, 33S)-. Grades: ≥90% by HPLC. CAS No. 89270-28-0. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
Cyclosporine Resolution M
Heterocyclic Organic Compound. CAS No. 5072-4-9. Catalog: ACM1158650.
Cyclosporine resolution mixture(25 mg)
Heterocyclic Organic Compound. Alternative Names: CYCLOSPORINE RESOLUTION MIXTURE (25 MG);Cyclosporine Resolution Mixture. CAS No. 108027-45-8. Catalog: ACM108027458.
Cyclosporin F
Cyclosporin F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 83574-28-1. Molecular Formula: C62H111N11O11. Mole Weight: 1186.64. Catalog: APB83574281.
Cyclosporin H
An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Group: Biochemicals. Grades: Highly Purified. CAS No. 83602-39-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cyclosporin H Isomer
Cyclosporin H Isomer. Uses: For analytical and research use. Group: Impurity standards. CAS No. 83602-43-1. Molecular Formula: C62H111N11O12. Mole Weight: 1202.64. Catalog: APB83602431.
Cyclosporin I
Cyclosporin I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 83563-93-3. Molecular Formula: C62H111N11O12. Mole Weight: 1202.64. Catalog: APB83563933.
Cyclosporin Impurity 2
Cyclosporin Impurity 2 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (2S,3R,4R,E)-3,8-dihydroxy-4-methyl-2-(methylamino)oct-6-enoic acid. Grades: ≥90% by HPLC. Molecular formula: C10H19NO4. Mole weight: 217.26.
Cyclosporin Impurity 4
Cyclosporin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59865-23-5. Molecular Formula: C10H19NO3. Mole Weight: 201.27. Catalog: APB59865235.
Cyclosporin Impurity 5
Cyclosporin Impurity 5 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 10-[(2S)-2-Aminobutanoic acid]cyclosporin A; Cyclosporin A, 10-[(2S)-2-aminobutanoic acid]-; [Abu5]cyclosporin; cyclo[Abu-Sar-N(Me)Leu-Abu-N(Me)Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)]; cyclo[(N-(((2S)-2-aminobutyryl)-sarcosyl-N-methyl-L-leucyl)-(2S)-2-aminobutyryl)-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-(4R)-4-[(E)-but-2-enyl]-4-methyl-L-threonyl]; (3S, 6S, 9S, 12R, 15S, 18S, 21S, 24S, 30S, 33S)-21, 30-diethyl-33-((1R, 2R, E)-1-hydroxy-2-methylhex-4-en-1-yl)-6, 9, 18, 24-tetraisobutyl-3-isopropyl-1, 4, 7, 10, 12, 15, 19, 25, 28-nonamethyl-1, 4, 7, 10, 13, 16, 19, 22, 25, 28, 31-undecaazacyclotritriacontan-2, 5, 8, 11, 14, 17, 20, 23, 26, 29, 32-undecaone. Grades: ≥95%. CAS No. 437611-17-1. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin Impurity 5
Cyclosporin Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1907654-63-0. Molecular Formula: C58H103N11O12. Mole Weight: 1146.53. Catalog: APB1907654630.
Cyclosporin Impurity 6
Cyclosporin Impurity 6 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Grades: ≥90% by HPLC. CAS No. 1357559-31-3. Molecular formula: C8H15BF3N2K. Mole weight: 246.13.
Cyclosporin L
Cyclosporin L is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (3R,4R)-3-Hydroxy-5-[(E)-1-propenyl]cyclo[L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-]. Grades: ≥90% by HPLC. CAS No. 108027-39-0. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin L
Cyclosporin L. Uses: For analytical and research use. Group: Impurity standards. CAS No. 108027-39-0. Molecular Formula: C61H109N11O12. Mole Weight: 1188.61. Catalog: APB108027390.
Cyclosporin L Related Compound 1
Cyclosporin L Related Compound 1 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (E)-(R)-2-Methyl-hex-4-enoic acid. Grades: ≥90% by HPLC. CAS No. 93553-73-2. Molecular formula: C7H12O2. Mole weight: 128.17.
Cyclosporin L Related Compound 2
Cyclosporin L Related Compound 2 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (R,E)-2-methylhex-4-en-1-ol; (E)-(R)-2-Methyl-hex-4-en-1-ol; (2R,4E)-2-Methyl-4-hexen-1-ol; 4-Hexen-1-ol, 2-methyl-, (2R,4E)-. Grades: ≥90% by HPLC. CAS No. 104372-56-7. Molecular formula: C7H14O. Mole weight: 114.18.
Cyclosporin L Related Compound 3
Cyclosporin L Related Compound 3 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (E)-(2R,3S,4R)-2-Amino-3-hydroxy-4-methyl-oct-6-enoic acid; (2R,3S,4R,6E)-2-amino-3-hydroxy-4-methyl-6-octenoic acid; 2-Amino-4-[(2E)-2-buten-1-yl]-2,4,5-trideoxy-L-arabinonic acid; L-Arabinonic acid, 2-amino-4-[(2E)-2-buten-1-yl]-2,4,5-trideoxy-. Grades: ≥90% by HPLC. CAS No. 174292-85-4. Molecular formula: C9H17NO3. Mole weight: 187.24.
Cyclosporin T
Cyclosporin T is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-L-Leu-N-methyl-L-Val-); Cyclosporin A, 4-L-leucine-; 4-L-Leucinecyclosporin A; Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]. Grades: ≥90% by HPLC. CAS No. 108027-44-7. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin T
Cyclosporin T. Uses: For analytical and research use. Group: Impurity standards. CAS No. 108027-44-7. Molecular Formula: C61H109N11O12. Mole Weight: 1188.61. Catalog: APB108027447.
Cyclosporin U
Cyclosporin U is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporine U (Ciclosporin EP Impurity D); Cyclo[[(E)-(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl]-L-2-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl]; Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-L-leucyl); cyclo[Abu-Sar-N(Me)Leu-Val-Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)]; cyclo[((2S)-2-aminobutyryl)-sarcosyl-N-methyl-L-leucyl-L-valyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-(4R)-4-[(E)-but-2-enyl]-4-methyl-L-threonyl]; Cyclosporin A, 11-L-leucine-; Cyclosporin Impurity 11. Grades: ≥90% by HPLC. CAS No. 108027-45-8. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin U
Cyclosporin U. Uses: For analytical and research use. Group: Impurity standards. CAS No. 108027-45-8. Molecular Formula: C61H109N11O12. Mole Weight: 1188.61. Catalog: APB108027458.
Cyclosporin V
Cyclosporin V is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporine V; Ciclosporin EP Impurity E; Cyclosporin A, 1-[(2S)-2-aminobutanoic acid]-; 1-[(2S)-2-Aminobutanoic acid]cyclosporin A; cyclo[Abu-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)-Abu-Sar-N(Me)Leu-Val-N(Me)Leu]; cyclo[(N-(((2S)-2-aminobutyryl)-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-(4R)-4-[(E)-but-2-enyl]-4-methyl-L-threonyl)-(2S)-2-aminobutyryl)-sarcosyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]. Grades: ≥90% by HPLC. CAS No. 108027-46-9. Molecular formula: C63H113N11O12. Mole weight: 1216.63.
Cyclosporin X
Cyclosporin X. Uses: For analytical and research use. Group: Impurity standards. CAS No. 108027-47-0. Molecular Formula: C62H111N11O12. Mole Weight: 1202.64. Catalog: APB108027470.
(1,11-seco)-Cyclosporin A Oxazolidinone Methylamide
(1,11-seco)-Cyclosporin A Oxazolidinone Methylamide, is an impurity of Cyclosporin A (C988900), which is an immunosuppressant drug widely used in organ transplantation to prevent rejection. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C65H114N12O14, Molecular Weight: 1234.60799999999. US Biological Life Sciences.
Worldwide
6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine]cyclosporin a
Heterocyclic Organic Compound. Alternative Names: 6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine] Cyclosporin A, 121584-52-9. CAS No. 121584-52-9. Molecular formula: C62H109N11O14. Mole weight: 1232.59. Appearance: White Solid. Purity: 0.96. IUPACName: [(3R,14S)-5-(dimethylamino)-3,15-dimethyl-14-[[(2S)-4-methyl-2-(methylamino)pentanoyl]amino]-1,6,13-trioxohexadecan-4-yl] acetate. Canonical SMILES: CC (C)CC (C (=O)NC (C (C)C)C (=O)CCCCCCC (=O)C (C (C (C)CC=O)OC (=O)C)N (C)C)NC. Catalog: ACM121584529.
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