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DBU acts as a nucleophile and can work as a catalyst [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1,8-Diazabicyclo[5.4.0]undec-7-ene. CAS No. 6674-22-2. Pack Sizes: 500 g. Product ID: HY-20556.
dC-H-Phosphonate, DBU Salt
dC-H-Phosphonate, DBU Salt is an immensely robust biochemical compound with paramount significance lying in the synthesis of phosphonate-modified DNA. It assumes the role of a nucleotide analog during DNA replication. Synonyms: 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyCytidine, 3'-H-phosphonate, DBU salt. Molecular formula: C46H52N5O9P. Mole weight: 849.35.
Fmoc-D-Dbu(Boc)-OH
Fmoc-D-Dbu(Boc)-OH. Group: Biochemicals. Alternative Names: (S)-Nb-Fmoc-Nγ-Boc-3,4-diaminobutyric acid. Grades: Highly Purified. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
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Fmoc-D-Dbu(Boc)-OH ≥97% (HPLC)
Fmoc-D-Dbu(Boc)-OH ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
Phthalimide DBU Salt
Phthalimide DBU Salt. Group: Biochemicals. Alternative Names: DBU Phthalimide Salt; Phthalimide 1, 8-Diazabicyclo[5. 4. 0]undec-7-ene Salt. Grades: Highly Purified. CAS No. 119812-51-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences.
1, 8-Diazabicyclo[5. 4. 0]undec-7-ene. Group: Biochemicals. Alternative Names: DBU; 2,3,4,6,7,8,9,10-Octahydropyrimidol[1,2-a]azepine. Grades: Highly Purified. CAS No. 6674-22-2. Pack Sizes: 500g, 1kg, 2kg, 5Kg, 10Kg. Molecular Formula: C9H16N2. US Biological Life Sciences.
Worldwide
1,8-Diazabicyclo[5.4.0]undec-7-ene
1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) can promote the methylation reaction of phenols, indoles and benzimidazoles with dimethyl carbonate under mild conditions. Synonyms: DBU; 1,8-Diazabicyclo[5.4.0]undecene-7; Alcanpoudre DBU 70-3KG; Amicure DBUE; Dabco DBU; Lupragen N 700; NSC 111184; NSC 230466; PC CAT DBU; Polycat DBU; U-CAT SA 851. Grades: ≥ 98%. CAS No. 6674-22-2. Molecular formula: C9H16N2. Mole weight: 152.24.
Fmoc-Dab(Dde)-OH
Fmoc-Dab(Dde)-OH. Uses: Peptide synthesis. Additional or Alternative Names: N-alpha-Fmoc-N-gamma-Dde-L-2,4-diaminobutyric acid, Fmoc-Dab(Dde), Fmoc-Dbu(Dde), N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-gamma-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-L-2,4-diaminobutyric acid. Product Category: Amino Acids. CAS No. 235788-61-1. Molecular formula: C29H32N2O6. Mole weight: 504.6. Purity: Peak Area by HPLC ≥95%. Canonical SMILES: CC(=C1C(=O)CC(CC1=O)(C)C)NCC[C@@H](C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24. Product ID: ACM235788611-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-[1-(2-hydroxy-4,4-dimethyl-6-oxocyclohexen-1-yl)ethylideneamino]butanoic acid.
Fmoc-Lys(Dde)-OH
Quasi-orthogonally-protected Lys derivative for Fmoc SPPS. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF. When removing Dde in the presence of allyl based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group. Lys(Dde) has been employed in the following applications: synthesis of branched peptides and di-epitopic peptides ; preparation of MAP core molecules and lipo-MAPs; construction of cyclic peptides , TASP molecules , templates for combinatorial chemistry and synthetic proteins ; preparation of peptides modified at the lysine side-chain.It has been reported that Dde can migrate from the side-chain of Lys to the unprotected side-chain of another Lys residue , and from the β-amino group to the α-amino group of Dpr. In the former instance, this problem can be overcome by using Fmoc-Lys(ivDde)-OH or using DBU/DMF (2:98) for Fmoc group removal.Full orthogonality of Dde with Fmoc has recently been demonstrated when hydroxylamine is used for Dde removal. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Lys(Dde)-OH, N-α-Fmoc-N-ε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-L-lysine. Product Category: Amino Acids. CAS No. 150629-67-7. Molecular formula: C31H36N2O6. Mole weight: 532.63. Product ID: ACM150629677. Alfa Chemistry ISO 9001:2015
Fmoc-Ser(PO(OBzl)OH)-OH
An excellent building block for the preparation of phosphoserine-containing peptides by Fmoc SPPS. This derivative can be introduced using standard activation methods, such as PyBOPand TBTU. The monoprotected phosphoserine residue once incorporated is stable to piperidine. Using this reagent, even peptides containing multiple phosphorylation sites can be prepared efficiently by standard Fmoc SPPS methods. Applications of this derivative include the preparation of phospholamban , a 52 residue peptide containing both phosphoserine and phosphothreonine, and human salivary statherin, a 42 residue phosphoserine peptide ; for other examples see references.Recently, β-piperidinylalanine formation has been shown to occur during Fmoc deprotection of N-terminal Ser(PO(OBzl)OH), particularly under microwave conditions. This side reaction can be eliminated by using cyclohexylamine or DBU just for this Fmoc deprotection step. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Ser(PO(OBzl)OH)-OH, N-α-Fmoc-O-benzyl-L-phosphoserine. Product Category: Amino Acids. CAS No. 158171-14-3. Molecular formula: C25H24NO8P. Mole weight: 497.43. Product ID: ACM158171143-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[hydroxy(phenylmethoxy)phosphoryl]oxypropanoic acid.