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A metabolite of Levobunolol and d-Bunolol. Group: Biochemicals. Alternative Names: 1,2,3,4-Tetrahydro-1-oxo-5-hydroxynaphthalene; 5-Hydroxy-α-tetralone; 1,2,3,4-Tetrahydro-5-hydroxynaphthyl-1-one; 5-Hydroxy-3,4-dihydro-1(2H)-naphthalenone; 3,4-Dihydro-5-hydroxy-1(2H)-naphthalenone; 5-Hydroxy-1,2,3,4-tetrahydronaphthalen-1-one; 5-Hydroxy-3,4-dihydro-2H-naphthalen-1-one. Grades: Highly Purified. CAS No. 28315-93-7. Pack Sizes: 10g. US Biological Life Sciences.
A HMG-COA reductase inhibitor; useful as anticholesteramic. Group: Biochemicals. Alternative Names: [2R-[2α,4α,4a β,5 β(2R*,4R*),6 β]]-4-(2,2-Dimethyl-1-oxobutoxy)-2,3,4,4a,5,6-hexahydro-6-methyl-5-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-2-naphthalenecarboxylic Acid. Grades: Highly Purified. CAS No. 114883-30-6. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
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Direct Blue 218
Direct Blue 218 is an azo dye used in diagnostic imaging. Used in the prediction of rat carcinogenisis. Also used in textile dyes contributing to textile effluents and wastewaters. Environmental toxin on US EPA Toxic Release Inventory list (TRI) list. Group: Biochemicals. Alternative Names: [Tetrahydrogen -3, 3'- [ (3, 3'-dihydroxy-4, 4'-biphenylylene ) bis (azo) ] bis [5-amino-4-hydroxy-2, 7-naphthalene disulfonato] (4-) ] di-Copper Tetrasodium Salt; [ μ - [ [3, 3'- [ (3, 3'-Dihydroxy [1, 1'-biphenyl] -4, 4'-diyl) bis (azo) ] bis [5-amino-4-hydroxy-2, 7-naphthalene disulfonato] ] (8-) ] ] di-Cuprate (4-) Tetra sodium ; [ μ - [ [3, 3'- [ [3, 3'-Di (hydroxy- κ O) [1, 1'-biphenyl] -4, 4'-diyl] bis (azo- κ N1) ] bis [5-amino-4- (hydroxy- κ O) -2, 7-naphthalene disulfonato] ] (8-) ] ] di-Cuprate (4-) Tetrasodium;3,3'-[(3,3'-Dihydroxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-amino-4-hydroxy-2,7-Naphthalenedisulfonic Acid Copper Complex; Amanil Supra Blue 9GL; C.I. 24401; Carta Blue VP; Direct Blue 218; Fastusol Blue 9GLP; Intralite Blue 8GLL; Pontamine Bond Blue B; Pontamine Fast Blue 7GLN. Grades: Purified. CAS No. 28407-37-6. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C??H??Cu?N?Na?O??S?, Molecular Weight: 1087.81. US Biological Life Sciences.
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Juglomycin A
Juglomycin A is originally isolated from Str. distatochromogenes var. juglonensis 190-2. It has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg. Synonyms: (-)-Juglomycin A; 1,4-Naphthalenedione,5-hydroxy-2-[(2R,3R)-tetrahydro-3-hydroxy-5-oxo-2-furanyl]-. CAS No. 38637-88-6. Molecular formula: C14H10O6. Mole weight: 274.22.
Nadolol Impurity D
An impurity of Nadolol, which is a non-selective beta blocker used in the treatment of high blood pressure and chest pain. Synonyms: 2,?3-Naphthalenediol, 5,?5'-[[(1,?1-dimethylethyl)?imino]?bis[(2-hydroxy-3,?1-propanediyl)?oxy]?]?bis[1,?2,?3,?4-tetrahydro- (9CI). Grades: > 95%. CAS No. 67247-26-1. Molecular formula: C30H43NO8. Mole weight: 545.68.
Oxantel pamoate
Oxantel Pamoate is used as an anthelmintic. It has typically been used in human and animal field as a standard treatment for intestinal worms. It may be used as a fumarate reductase inhibitor to kill the bacteria responsible for periodontal disease. Uses: Antinematodal agents. Synonyms: (E)-3-(2-(1-methyl-1,4,5,6-tetrahydropyrimidin-2-yl)vinyl)phenol 4,4'-methylenebis(3-hydroxy-2-naphthoate); 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid 3-[(1E)-2-(1,4,5,6-Tetrahydro-1-methyl-2-pyrimidinyl)ethenyl]phenol; Oxantel Ebonate; Telopar. Grades: 98%. CAS No. 68813-55-8. Molecular formula: C36H32N2O7. Mole weight: 604.65.
(1R-trans)-2-Chloro-N-propyl-N-(1,2,3,4-tetrahydro-1-hydroxy-7-methoxy-2-naphthalenyl)-acetamide is an intermediate in the synthesis of Naxagolide Hydrochloride (N379800), which is a dopamine D2-receptor agonist. Used for treatment of extrapyramidal disorders. Antiparkinsonian drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 110936-07-7. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H22ClNO3, Molecular Weight: 311.8. US Biological Life Sciences.
3-[3-(4'-Bromo[1,1'-biphenyl]-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydroxy-2H-1-benzothiopyran-2-one. Group: Biochemicals. Alternative Names: 2H-1-Benzothiopyran-2-one, 3-(3-(4'-bromo(1,1'-biphenyl)-4-Yl)-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy-; Baraki; Difethiarol. Grades: Highly Purified. CAS No. 104653-34-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C31H23BrO2S. US Biological Life Sciences.
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3,5-Dihydrodiol Simvastatin (Mixture of Diastereomers).
A metabolite of Simvastatin. Group: Biochemicals. Alternative Names: [1S-[1α,3α,4 β,6α,7 β,8 β(2S*,4S*),8a β]]-Butanoic Acid 2,2-Dimethyl-1,2,3,4,6,7,8,8a-octahydro-4,6-dihydroxy-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester. Grades: Highly Purified. CAS No. 159143-77-8. Pack Sizes: 10mg. US Biological Life Sciences.
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3-Hydroxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?7,?8,?8a-hexahydro-3-hydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester. Grades: > 95%. CAS No. 134523-09-4. Molecular formula: C25H38O6. Mole weight: 434.57.
3-Methylene Simvastatin Impurity
3-Methylene Simvastatin Impurity. Group: Biochemicals. Alternative Names: [1S-[1α,3α,7 β,8 β(2S*,4S*),8a β]]-2,2,3-Trimethyl-3-butenoic Acid 1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester; Simvastatin Impurity G. Grades: Highly Purified. CAS No. 79902-62-8. Pack Sizes: 5mg. Molecular Formula: C26H38O5, Molecular Weight: 430.58. US Biological Life Sciences.
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(3R)-Hydroxperoxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?3R,?7S,?8S,?8aR)?-1,?2,?3,?7,?8,?8a-hexahydro-3-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester. Grades: > 95%. CAS No. 1092716-42-1. Molecular formula: C25H38O7. Mole weight: 450.57.
(3S, 5S)-Dihydroxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?4,?6,?7,?8,?8a-octahydro-4,?6-dihydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester, [1S-[1α, ?3α, ?4β, ?6α, ?7β, ?8β(2S*, ?4S*)?, ?8aβ]?]?- (9CI). Grades: > 95%. CAS No. 159143-77-8. Molecular formula: C25H40O7. Mole weight: 452.58.
(3S)-Hydroxperoxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?3S,?7S,?8S,?8aR)?-1,?2,?3,?7,?8,?8a-hexahydro-3-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester. Grades: > 95%. CAS No. 1092716-44-3. Molecular formula: C25H38O7. Mole weight: 450.57.
3(S)-Hydroxy Simvastatin.
A derivative of Simvastatin. Group: Biochemicals. Alternative Names: 2,2-Dimethylbutanoic Acid [1S-[1α,6α,7 β,8 β(2S*,4S*),8a β]]-1,2,6,7,8,8a-Hexahydro-6-hydroxy-3,7-dimethyl)-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester. Grades: Highly Purified. CAS No. 133645-46-2. Pack Sizes: 2.5mg. US Biological Life Sciences.
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4a,5-Dihydro lovastatin
4a,5-Dihydro lovastatin. Group: Biochemicals. Alternative Names: (2S)-2-Methylbutanoic acid (1S,3S,4aR,7S,8S,8aS)-1,2,3,4,4a,7,8,8a-octahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester; (+)-Dihydromevinolin; Dihydrolovastatin. Grades: Highly Purified. CAS No. 77517-29-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C24H38O5. US Biological Life Sciences.
Worldwide
(4S)-Hydroxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?4,?7,?8-hexahydro-4-hydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester, [1S-[1α, ?3α, ?4β, ?7β, ?8β(2S*, ?4S*)?]?]?- (9CI). Grades: > 95%. CAS No. 149949-05-3. Molecular formula: C25H38O6. Mole weight: 434.57.
Intermediate for the preparation of Simvastatin analogs as HMG-CoA reductase inhibitors. Group: Biochemicals. Alternative Names: 2,2-Dimethylbutanoic Acid [1S-[1α,3α,4 β,4aα,7 β,8 β (2S*, 4S*) ] ] -4-Chloro-8- [2- [4- [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] tetrahydro-6-oxo-2H-pyran-2-yl] ethyl] -1, 2, 3, 4, 4a, 7, 8, 8a-octahydro-4a-hydroxy-3, 7-dimethyl-1-naphthalenyl Ester. Grades: Highly Purified. CAS No. 123852-10-8. Pack Sizes: 10mg. US Biological Life Sciences.
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5-Chloro-6-oxo Simvastatin
Intermediate in the preparation of Simvastatin analogs. Group: Biochemicals. Alternative Names: [1S-[1α,3α,4 β,7 β,8 β(2S*,4S*),8a β]]-2,2-Dimethylbutanoic Acid 4-Chloro-1,2,3,4,6,7,8,8a-octahydro-3,7-dimethyl-6-oxo-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester. Grades: Highly Purified. CAS No. 134395-21-4. Pack Sizes: 5mg. US Biological Life Sciences.
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5-Hydroxy-DPAT hydrobromide
A potent and selective dopamine (DA) D2 receptor agonist developed as a PET agent. Synonyms: Hydroxy-DPAT hydrobromide, 5-; 6-(Dipropylamino)-5,6,7,8-tetrahydro-1-naphthalenol hydrobromide; 5-OH-DPAT HBr. Grades: 99%. CAS No. 71787-83-2. Molecular formula: C16H25NO.HBr. Mole weight: 328.29.
6-Oxo Simvastatin is an analog of Simvastatin , a HMG-CoA reductase inhibitor. Group: Biochemicals. Alternative Names: 2,2-Dimethylbutanoic Acid (1S,7R,8R,8aR)-1,2,6,7,8,8a-Hexahydro-3,7-dimethyl-6-oxo-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; L 669262. Grades: Highly Purified. CAS No. 130468-11-0. Pack Sizes: 5mg. US Biological Life Sciences.
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6-Oxo-Simvastatin
6-Oxo Simvastatin a Potent HMG-CoA Reductase Inhibitor and an analog of Simvastatin. Synonyms: 2,2-Dimethylbutanoic Acid (1S,7R,8R,8aR)-1,2,6,7,8,8a-Hexahydro-3,7-dimethyl- 6-oxo-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; L 669262; 6-Oxo Simvastatin. Grades: > 95%. CAS No. 130468-11-0. Molecular formula: C25H36O6. Mole weight: 432.56.
6S)-Hydroperoxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?6S,?7R,?8S,?8aR)?-1,?2,?6,?7,?8,?8a-hexahydro-6-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester; Butanoic acid, 2,2-dimethyl-, 1,2,6,7,8,8a-hexahydro-6-hydroperoxy-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1α, 6α, 7β, 8β(2S*, 4S*), 8aβ]]- (9CI). Grades: > 95%. CAS No. 149949-01-9. Molecular formula: C25H38O7. Mole weight: 450.57.
(6S)-Hydroxy Simvastatin
A derivative of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 2,2-Dimethylbutanoic Acid [1S-[1α, 6α, 7β, 8β(2S*, 4S*), 8aβ]]-1, 2, 6, 7, 8, 8a -Hexahydro-6-hydroxy-3,7-dimethyl)-8-[2-(tetrahydro -4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester; 3'(S)-Hydroxy Simvastatin. Grades: > 95%. CAS No. 133645-46-2. Molecular formula: C25H38O6. Mole weight: 434.58.
7-Hydroxy-DPAT hydrobromide is a dopamine D3 receptor agonist (Ki = ~ 1, 10, 650 and ~ 5000 nM for D3, D2, D4 and D1 receptors, respectively). Synonyms: 2-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide (1:1); 7-OH-DPAT Hydrobromide; (±)-7-Hydroxy-2-dipropylaminotetralin hydrobromide; 2-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide; 7-Hydroxy(N,N-dipropyl-2-amino)tetralin hydrobromide; 7-Hydroxy-2-dipropylaminotetralin hydrobromide. Grades: ≥99% by HPLC. CAS No. 76135-30-3. Molecular formula: C16H25NO.HBr. Mole weight: 328.28.
8-Hydroxy-PIPAT oxalate
8-Hydroxy-PIPAT oxalate is a high affinity 5-HT1A receptor agonist (Kd = 0.38 nM) that has the potential for the treatment of disorders of serotonin release. Synonyms: 1-Naphthalenol, 5,6,7,8-tetrahydro-7-[[(2E)-3-iodo-2-propen-1-yl]propylamino]-, ethanedioate (1:1); (RS)-trans-8-Hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin oxalate; (E)-7-((3-iodoallyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol oxalic acid; 7-{[(2E)-3-Iodo-2-propen-1-yl](propyl)amino}-5,6,7,8-tetrahydro-1-naphthalenol ethanedioate (1:1). Grades: ≥98% by HPLC. CAS No. 1451210-48-2. Molecular formula: C16H22INO.C2H2O4. Mole weight: 461.29.
Andrographolide
Andrographolide is a labdane diterpenoid. Andrographolide is the main bioactive component isolated from the medicinal plant Andrographis paniculata. Andrographolide showed significant antihepatotoxic action in P. berghei K173- induced hepatic damage in M. natalensis. Andrographolide inhibits tumor necrosis factor-α (TNF-α)-induced intercellular adhesion mol.-1 (ICAM-1) expression and adhesion of HL-60 cells onto human umbilical vein endothelial cells (HUVEC), which are associated with inflammatory diseases. These findings suggest that Andrographolide may have potential as a cardiovascular-protective agent. Group: Biochemicals. Alternative Names: (3E, 4S) -3- [2- [ (1R, 4aS, 5R, 6R, 8aS) -Decahydro-6-hydroxy-5- (hydroxymethyl) -5, 8a-dimethyl-2-methylene-1-naphthalenyl] ethylidene] dihydro-4-hydroxy-2 (3H) -furanone; [1R-[1α[E(S*)],4a β , 5α , 6α , 8aα ] ] -3- [2- [Decahydro-6-hydroxy-5- (hydroxymethyl) -5, 8a-dimethyl-2-methylene-1-naphthalenyl] ethylidene] dihydro-4-hydroxy-2 (3H) -furanone; 3α,14,15,18-Tetrahydroxy-5 β,9 βH,10α-labda-8(20),12-dien-16-oic Acid γ-Lactone; Andrographis; Andrographolid. Grades: Highly Purified. CAS No. 5508-58-7. Pack Sizes: 500mg. US Biological Life Sciences.
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ARV-471
ARV-471, an oral estrogen receptor PROTAC protein degrader for the treatment of breast cancer, is an heterobifunctional molecule that promotes the interaction between estrogen receptor alpha and intracellular E3 ligase complexes. It leads to ubiquitylation and subsequent degradation of estrogen receptors through the proteasome. In ER positive breast cancer cell lines, it has a strong ability to degrade ER with a half-maximal degradation concentration (DC50) of ~2 nM. Synonyms: ARV471; ARV 471; (S)-3-(5-(4-((1-(4-((1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione; 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[4-[[1-[4-[(1R,2S)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl]phenyl]-4-piperidinyl]methyl]-1-piperazinyl]-2H-isoindol-2-yl]-, (3S)-; Vepdegestrant; (3S)-3-[1,3-Dihydro-1-oxo-5-[4-[[1-[4-[(1R,2S)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl]phenyl]-4-piperidinyl]methyl]-1-piperazinyl]-2H-isoindol-2-yl]-2,6-piperidinedione. Grades: ≥95%. CAS No. 2229711-68-4. Molecular formula: C45H49N5O4. Mole weight: 723.90.
Dihydromevinolin is an impurity in Lovastatin bulk drug. It is produced by the strain of Aspergollus terreus. Synonyms: 4a,5-Dihydro Lovastatin; (2S)-2-Methylbutanoic Acid (1S,3S,4aR,7S,8S,8aS)-1,2,3,4,4a,7,8,8a-Octahydro- 3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; (+)-Dihydromevinolin; Dihydrolovastatin; Dihydromevinol. Grades: > 95%. CAS No. 77517-29-4. Molecular formula: C24H38O5. Mole weight: 406.56.
It has the activity of inhibiting HMG-CoA reductase, and it is produced by the strain of Penicillum citrinum SANK. Synonyms: Compactin diol lactone; ML-236A; 6-(2-(1,2,6,7,8,8a-Hexahydro-8-hydroxy-2-methyl-1-naphthalenyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one; desmethylmonacolin J; Antibiotic ML 236A. CAS No. 58889-19-3. Molecular formula: C18H26O4. Mole weight: 306.40.
Pravastatin Impurity D
An impurity of Pravastatin.Pravastatin is a member of the drug class of statins. It can be used for lowering cholesterol and preventing cardiovascular disease. Synonyms: (2S)-2-Methylbutanoic Acid (1S,3S,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; R 414;Pravastatin Lactone. Grades: > 95%. CAS No. 85956-22-5. Molecular formula: C23H34O6. Mole weight: 406.52.
Pravastatin Lactone-d3
Pravastatin Lactone-D3 is primarily utilized as an internal standard in analytical chemistry for quantifying the concentration of pravastatin in various samples through techniques such as mass spectrometry. This deuterated compound provides a methodological advantage due to its similar physicochemical properties to non-deuterated pravastatin while being distinguishable based on its mass difference. Group: 2h labeled compounds. Alternative Names: (2S)-2-(Methyl-d3)butanoic Acid (1S,3S,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester. CAS No. 1217769-04-4. Molecular formula: C23H31D3O6. Mole weight: 409.54. Appearance: Solid. IUPACName: [(1S,3S,7S,8S,8aR)-3-hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-(trideuteriomethyl)butanoate. Canonical SMILES: [2H]C ([2H]) ([2H])[C@@H] (CC)C (=O)O[C@H]1C[C@@H] (C=C2[C@H]1[C@H] ([C@H] (C=C2)C)CC[C@@H]3C[C@H] (CC (=O)O3)O)O. Catalog: ACM1217769044.
(R)-(+)-8-Hydroxy-DPAT hydrobromide
(R)-(+)-8-Hydroxy-DPAT hydrobromide is a full 5-HT1A serotonin receptor agonist. It decreases hippocampal 5-HT levels following systemic administration in rats in vivo. Synonyms: 1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide (1:1), (7R)-; (R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide; 1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, monohydrobromide, (7R)-; 1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide, (R)-; (+)-8-OH-DPAT hydrobromide; (2R)-(+)-8-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide; R(+)-8-Hydroxy DPAT HBr. Grades: ≥99% by HPLC. CAS No. 78095-19-9. Molecular formula: C16H25NO.HBr. Mole weight: 328.29.
rac-8-hydroxy-2-dipropylaminotetralin hydrobromide. Group: Biochemicals. Alternative Names: 7-(Dipropylamino)-5,6,7,8-tetrahydro-1-naphthalenol hydrobromide; (+/-)-8-Hydroxy(N,N-dipropyl-2-amino)tetralin hydrobromide; 8-OH DPAT. Grades: Highly Purified. CAS No. 76135-31-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H26BrNO. US Biological Life Sciences.
Worldwide
Simvastatin
A competitive inhibitor of HMG-CoA reductase. A synthetic analog of lovastatin. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Alternative Names: 2,2-Dimethylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; (+)-Simvastatin; Cholestat; Lipex; Novo-Simvastatin; Simvotin; Sinvacor; Statin; Zorced; MK-733, Synvinolin, BRN 4768037; Zocor, Liponorm. Grades: Highly Purified. CAS No. 79902-63-9. Pack Sizes: 25g, 50g, 100g, 250g. Molecular Formula: C??H??O?, Molecular Weight: 418.57. US Biological Life Sciences.
Worldwide
Simvastatin-d6
Deuterated Simvastatin, a competitive inhibitor of HMG-CoA reductase. A deuterated synthetic analog of lovastatin. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Alternative Names: 2,2-(Dimethyl-d6)butanoic Acid(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; (+)-Simvastatin-d6; Cholestat-d6; Lipex-d6; Novo-Simvastatin-d6; Simvotin-d6; Sinvacor-d6; Statin-d6; Zocor-d6; Zorced-d6. Grades: Highly Purified. CAS No. 1002347-71-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C??H??D?O?, Molecular Weight: 424.6. US Biological Life Sciences.
Worldwide
Simvastatin EP Impurity F
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Simvastatin USP Related Compound F; epi-Lovastatin; Lovastatin epimer; (2R)-2-Methylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester. Grades: 95%. CAS No. 79952-44-6. Molecular formula: C24H36O5. Mole weight: 404.55.
Simvastatin EP Impurity N
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Methylsimvastatin; 5-Methylsimvastatin; 2-Methyl Simvastatin (Mixture Of Diasteroisomers); 2,2-Dimethyl-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-5-methyl-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester Butanoic Acid. CAS No. 774611-54-0. Molecular formula: C26H40O5. Mole weight: 432.59.
Simvastatin Impurity G
A metabolite of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 2,2-Dimethylbutanoic Acid (1S,7S,8S,8aR)-1,2,3,7,8,8a- Hexahydro-7-methyl-3-methylene-8-[2-[(2R,4R)-tetrahydro -4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; 6'-Exomethylene Simvastatin. Grades: > 95%. CAS No. 121624-18-8. Molecular formula: C25H36O5. Mole weight: 416.56.
(S,S)-3-Hydroxy Lovastatin
(S,S)-3-Hydroxy Lovastatin is a metabolite of Lovastatin. Synonyms: [1S-[1α(2R*, 3R*), 3α, 7β, 8β(2S*, 4S*), 8aβ]]-3-Hydroxy-2-methylbutanoic Acid 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran- 2-yl)ethyl]-1-naphthalenyl Ester. Grades: > 95%. CAS No. 127910-58-1. Molecular formula: C24H36O6. Mole weight: 420.54.
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