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2-(2-(2-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)ethoxy)acetic acid. Uses: Designed for use in research and industrial production. Product Category: E3 Ligase Ligand-Linker. CAS No. 2172820-08-3. Molecular formula: C28H38N4O8S. Mole weight: 590.6884. Purity: 0.95. IUPACName: 2-[2-[2-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-2-oxoethoxy]ethoxy]acetic acid. Product ID: PR2172820083. Alfa Chemistry ISO 9001:2015 Certified.
2-[2-(Dimethylamino)ethoxy]ethanol
Liquid. Uses: Used for the preparation of low-density packaging foams. Group: Polymerization reagents. Alternative Names: 2-(2-N ,N -Dimethylaminoethoxy)ethanol, N ,N -Dimethyl-2-(2-aminoethoxy)ethanol, N ,N -Dimethyl[2-(2-hydroxyethoxy)ethyl]amine. CAS No. 1704-62-7. Pack Sizes: Packaging 250 mL in poly bottle 1 L in poly bottle. Product ID: 2-[2-(dimethylamino)ethoxy]ethanol. Molecular formula: 133.19. Mole weight: (CH3)2NCH2CH2OCH2CH2OH. CN(C)CCOCCO. 1S/C6H15NO2/c1-7(2)3-5-9-6-4-8/h8H, 3-6H2, 1-2H3. YSAANLSYLSUVHB-UHFFFAOYSA-N. >95.0%(GC)(T).
Applications in medical research, drug-release, nanotechnology, materials research and cell culture. In the study of ligand, polypeptide synthesis support, graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. Group: Biochemicals. Alternative Names: NH2-PEG3-CH2CH2COOtBu. Grades: Highly Purified. CAS No. 252881-74-6. Pack Sizes: 5g. Molecular Formula: C13H27NO5, Molecular Weight: 277.4. US Biological Life Sciences.
[2S-(2α,3 β,4 β ) ] -3- [2- (1, 1-Di methyl ethoxy) -2-oxoethyl ] -4- (1- methyl ethenyl ) -1, 2-pyrrolidinedicarboxyl ic Acid Bis(1,1-Dimethylethyl) Ester is an intermediate in the synthesis of Domoic Acid (D531300), an excitatory amino acid isolated from the red alga Chondria armata Okamura. Group: Biochemicals. Grades: Highly Purified. CAS No. 191601-07-7. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H39NO6. US Biological Life Sciences.
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4-Hydroxy Toremifene-d6
The labeled analogue of -Hydroxy Toremifene, a metabolite of Toremifene. Group: Biochemicals. Alternative Names: 4- [ (4Z) -3-Chloro-1- [ [4- [2- [ (dimethyl-d6) amino] ethoxy] phenyl] phenylmethylene] propyl] phenol; 4- [ (1Z) -3-chloro-1- [ [4- [2- [ (dimethyl-d6) amino] ethoxy] phenyl] phenylmethylene] propyl] phenol; EM 880. Grades: Highly Purified. CAS No. 352233-94-4. Pack Sizes: 1mg. US Biological Life Sciences.
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4-Pivaloyloxy Toremifene
Protected 4-Hydroxy Toremifene , a metabolite of Toremifene. Group: Biochemicals. Alternative Names: 4- [ (4Z) -3-Chloro-1- [ [4- [2- [ (dimethyl-d6) amino] ethoxy] phenyl] phenylmethylene] propyl] -1-pivaloylphenol. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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4-Pivaloyloxy Toremifene-d6
Protected 4-Hydroxy Toremifene , a metabolite of Toremifene. Group: Biochemicals. Alternative Names: 4- [ (4Z) -3-Chloro-1- [ [4- [2- [ (dimethyl-d6) amino] ethoxy] phenyl] phenylmethylene] propyl] -1-pivaloylphenol-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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5α-reductase-IN-1
An inhibitor of 5α-reductase. Synonyms: Butanoic acid, 4-[2-[[2, 3-dimethyl-4-[1-[4- (2-methylpropyl) phenyl]ethoxy]benzoyl]amino]phenoxy]-. CAS No. 119348-12-8. Molecular formula: C31H37NO5. Mole weight: 503.63.
8-(Boc-amino)-3,6-dioxaoctanoic acid·DCHA
8-(Boc-amino)-3,6-dioxaoctanoic acid·DCHA. Group: Biochemicals. Alternative Names: (2-[2- (Boc-amino) ethoxy]ethoxy) acetic acid dicyclohexylamine; 2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid dicyclohexylamine. Grades: Highly Purified. CAS No. 560088-79-1. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
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ACBI1
ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 can induce anti-proliferative effects and apoptosis. Synonyms: ACBI 1; ACBI-1; (2S,4R)-N-(2-(2-(4-((4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)methyl)phenoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide. CAS No. 2375564-55-7. Molecular formula: C49H58FN9O7S. Mole weight: 936.12.
Adefovir dime Impurity
Adefovir dime Impurity. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ( ( ( (2- (6- ( ( ( (9- (2- (phosphorylmethoxy)ethyl)-9H-purin-6-yl)amino)methyl)amino)-9H-purin-9-yl)ethoxy)methyl)phosphoryl)tetrakis (oxy))tetrakis (methylene) tetrakis(2,2-dimethylpropanoate). CAS No. 323201-05-4. Molecular Formula: C41H64N10O16P2. Mole Weight: 1014.95. Catalog: APB323201054.
Adefovir Dipivoxil
A nucleotide analog, useful as an oral reverse transcriptase inhibitor (ntRTI). Group: Biochemicals. Alternative Names: 2,2-Dimethyl-propanoic Acid 1, 1'- [ [ [ [2- (6-Amino-9H-purin-9-yl) ethoxy] methyl] phosphinylidene] bis (oxymethylene) ] Ester; Hepsera; Preveon; bis(POM)-PMEA. Grades: Highly Purified. CAS No. 142340-99-6. Pack Sizes: 25mg. US Biological Life Sciences.
An impurity of Adefovir, a medication used for the treatment of infections with hepatitis B virus. Synonyms: Mono-POM Ethyl Adefovir; Mono(pivaloyloxymethyl) Ethyl Adefovir; 2,2-Dimethylpropanoic Acid [ [ [ [2- (6-amino-9H-purin-9-yl) ethoxy] methyl] ethoxyphosphinyl] oxy] methyl ester. Grades: > 95%. CAS No. 142341-04-6. Molecular formula: C16H26N5O6P. Mole weight: 415.39.
Adefovir Impurity 17
Adefovir Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ( ( ( (2- (6-amino-9H-purin-9-yl) ethoxy) methyl) ( (pivaloyloxy) methoxy) phosphoryl) oxy) methyl 2,2-dimethylbutanoate. Molecular Formula: C21H34N5O8P. Mole Weight: 515.5. Catalog: APB02841.
Adefovir Impurity 23
Adefovir Impurity 23. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: dimethyl ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonate. CAS No. 126352-61-8. Molecular Formula: C10H16N5O4P. Mole Weight: 301.24. Catalog: APB126352618.
Adefovir Impurity 28
Adefovir Impurity 28. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ( ( ( (2- (6-amino-7H-purin-7-yl)ethoxy)methyl)phosphoryl)bis (oxy))bis (methylene) bis(2,2-dimethylpropanoate). Molecular Formula: C20H32N5O8P. Mole Weight: 501.47. Catalog: APB02838.
Adefovir Impurity 31
Adefovir Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ( ( ( (2- (6- ( (3, 4-dihydroxy-6- (hydroxymethyl)-5- ( (3, 4, 5-trihydroxy-6- (hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis (oxy))bis (methylene) bis(2,2-dimethylpropanoate). Molecular Formula: C32H52N5O18P. Mole Weight: 825.75. Catalog: APB02834.
Adefovir Impurity 5
Adefovir Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ( (hydroxy ( (2- (6- ( ( ( (9- (2- ( (hydroxyhydrophosphoryl) methoxy) ethyl) -9H-purin-6-yl) amino) methyl) amino) -9H-purin-9-yl) ethoxy) methyl) phosphoryl) bis (oxy) ) bis (methylene) bis(2,2-dimethylpropanoate). Molecular Formula: C29H44N10O12P2. Mole Weight: 786.67. Catalog: APB02846.
Adefovir Impurity 6
Adefovir Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ( ( ( (2- (6- ( ( ( (9- (2- ( (hydroxy ( (pivaloyloxy) methoxy) phosphoryl) methoxy) ethyl) -9H-purin-6-yl) amino) methyl) amino) -9H-purin-9-yl) ethoxy) methyl) phosphoryl) bis (oxy) ) bis (methylene) bis(2,2-dimethylpropanoate). Molecular Formula: C35H54N10O14P2. Mole Weight: 900.81. Catalog: APB02847.
Adefovir methylol group Impurity
Adefovir methylol group Impurity. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ( ( ( (2- (6- ( (hydroxymethyl)amino)-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis (oxy))bis (methylene) bis(2,2-dimethylpropanoate). Molecular Formula: C21H34N5O9P. Mole Weight: 531.5. Catalog: APB02848.
Adefovir Monopivoxil
The monoester metabolite of the adefovir prodrug Adefovir Dipivoxil. Group: Biochemicals. Alternative Names: Mono-POM Adefovir; Mono (pivaloyloxymethyl) Adefovir; 2,2-Dimethylpropanoic Acid [ [ [ [2- (6-amino-9H-purin-9-yl) ethoxy] methyl] hydroxyphosphinyl] oxy] methyl Ester. Grades: Highly Purified. CAS No. 142341-05-7. Pack Sizes: 5mg. US Biological Life Sciences.
Alpha-[{(1,1-diemethylethyl)amino}methyl]-3-(ethoxy-methyl)-4-hydroxy-benzenemethanol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Levalbuterol related compound E, CHEMBL3304091, BIIK-0277, Levalbuterol related compound E [USP], Levalbuterol related compound E RS [USP], alpha-(((1,1-Dimethylethyl)amino)methyl)-3-(ethoxymethyl)-4-hydroxy-benzenemethanol, Benzenemethanol, alpha-(((1,1-dimethylethyl)amino)methyl)-3-(ethoxymethyl)-4-hydroxy-, 754926-25-5. Product Category: Heterocyclic Organic Compound. CAS No. 754926-25-5. Molecular formula: C15H25NO3. Mole weight: 267.363900 [g/mol]. Purity: 0.96. IUPACName: 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(ethoxymethyl)phenol. Canonical SMILES: CCOCC1=C(C=CC(=C1)C(CNC(C)(C)C)O)O. Product ID: ACM754926255. Alfa Chemistry ISO 9001:2015 Certified.
NH2-PEG3-C1-Boc is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 5 can be used in the synthesis of a series of PROTACs. NH2-PEG3-C1-Boc is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates, PROTACs and drug delivery methods. Synonyms: NH2-PEG3-C1-Boc; PROTAC Linker 5; Amino-PEG3-CH2CO2-t-butyl ester; H2N-PEG3-CH2COOtBu; Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester. Grades: >95%. CAS No. 189808-70-6. Molecular formula: C12H25NO5. Mole weight: 263.33.
Amoxicillin (3-Ethoxy-1-methyl-3-oxo-1-propenyl)?amino Diethylethanamine is an intermediate in the synthesis of Amoxicillin, which is an antibiotic used to treat a number of bacterial infections including middle ear infections, strep throat, pneumonia, skin infections, and urinary tract infections. Synonyms: [2S-[2α,5α,6β(S*)]]-6-[[[(3-Ethoxy-1-methyl-3-oxo-1-propenyl)amino](4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Diethylethanamine; Ethanamine, N,N-diethyl-, [2S-[2α,5α,6β(S*)]]-6-[[[(3-ethoxy-1-methyl-3-oxo-1-propenyl)amino](4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[(3-ethoxy-1-methyl-3-oxo-1-propenyl)amino](4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, [2S-[2α,5α,6β(S*)]]-, compd. with N,N-diethylethanamine (1:1). CAS No. 65959-31-1. Molecular formula: C22H27N3O7S.C6H15N. Mole weight: 578.72.
Amoxicillin Impurity T
Amoxicillin Impurity T. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,4S)-2-((R)-1-((R)-2-amino-2-(4-hydroxyphenyl)acetamido)-2-ethoxy-2-oxoethyl)-5,5-dimethylthiazolidine-4-carboxylic acid. Molecular Formula: C18H25N3O6S. Mole Weight: 411.47. Catalog: APB02670.
Avibactam Impurity X
Avibactam Impurity X. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium (S,Z)-5-((tert-butoxycarbonyl)amino)-6-ethoxy-1-(iodo-dimethylsulfinyl)-6-oxohex-1-en-2-olate. Molecular Formula: C15H27INNaO6S. Mole Weight: 499.34. Catalog: APB02736.
BDP FL-PEG4-amine TFA salt
BDP FL-PEG4-amine TFA salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BDPFL-PEG4-amine. Product Category: BODIPY Fluorophores. CAS No. 2183473-14-3. Molecular formula: C24H37BF2N4O5. Mole weight: 510.4. Purity: 0.98. IUPACName: N-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]-3-(2,2-difluoro-10,12-dimethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl)propanamide. Canonical SMILES: [B-]1(N2C(=CC=C2CCC(=O)NCCOCCOCCOCCOCCN)C=C3[N+]1=C(C=C3C)C)(F)F. Product ID: ACM2183473143-1. Alfa Chemistry ISO 9001:2015 Certified.
Belnacasan
Belnacasan is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Belnacasan inhibits interlukin-1β biosynthesis. Synonyms: VX 765, VX765, VX-765, Belnacasan; (2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]-N-[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]pyrrolidine-2-carboxamide. Grades: ≥98%. CAS No. 273404-37-8. Molecular formula: C24H33ClN4O6. Mole weight: 509.
Benzylpenicillin Impurity 1
Benzylpenicillin Impurity 1 is an impurity of Benzylpenicillin, which is an antibiotic used to treat a number of bacterial infections. Synonyms: (2R,4S)-2-[(1R)-1-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-2-ethoxy-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid. Molecular formula: C18H25N3O6S. Mole weight: 411.47.
CB-6644
CB-6644 is a novel allosteric selective inhibitor of the ruvbl1/2 complex with anti-cancer activity. CB-6644 blocks the ATPase activity of RUVBL1/2 with an IC50 of 15 nM. CB-6644 interacts specifically with RUVBL1/2 in cancer cells, leading to cell death. Importantly, drug-acquired-resistant cell clones have amino acid mutations in either RUVBL1 or RUVBL2, suggesting that cell killing is an on-target consequence of RUVBL1/2 engagement. In xenograft models of acute myeloid leukemia and multiple myeloma, CB-6644 significantly reduced tumor growth without obvious toxicity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CB-6644; CB 6644; CB6644. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2316817-88-4. Molecular formula: C29H34ClFN4O5. Mole weight: 573.06. Purity: >96%. IUPACName: 5-Chloro-2-ethoxy-4-fluoro-N-(4-((3-(methoxymethyl)-1-oxo-6,7-dihydro-1H,5H-benzo[c]pyrazolo[1,2-a][1,2]diazepin-2-yl)amino)-2,2-dimethyl-4-oxobutyl)benzamide. Canonical SMILES: O=C(NCC(C)(C)CC(NC(C1=O)=C(COC)N2N1C3=CC=CC=C3CCC2)=O)C4=CC(Cl)=C(F)C=C4OCC. Product ID: ACM2316817884. Alfa Chemistry ISO 9001:2015 Certified.
Cilazapril
Cilazapril is a very potent and highly effective angiotensin-converting enzyme inhibitor (ACE inhibitor). It is used for the treatment of hypertension and congestive heart failure. lt is a monoethyl ester. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat by non-specific esterases. It is known that the diacid form is more potent. It has been listed. Uses: Cilazapri is used for the treatment of hypertension and congestive heart failure. Synonyms: Cilazapril; Ro 34-2848; Ro-34-2848; Ro34-2848. 7-[ (2-amino-2-carboxylatoethyl) thio]-2-[[ (2, 2-dimethylcyclopropyl) carbonyl]amino]hept-2-enoate; 6H-Pyridazino[1, 2-a][1, 2]diazepine-1-carboxylic acid, 9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-, (1S,9S)-;6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, 9-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-, [1S-[1α,9α(R*)]]-;Ro 31-2848;(1S,9S)-9-[(S)-1-Ethoxycarbonyl-3-phenylpropylamino]-10-oxoperhydropyridazino[1,2-a][1,2]diazepine-1-carboxylic acid; Inhibace; Vascace; Cilazaprilum; (4S, 7S)-7-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-6-oxo-1, 2, 3, 4, 7, 8, 9, 10-octahydropyridazino[1, 2-a]diazepine-4-carboxylic acid. Grades: >98%. CAS No. 88768-40-5. Molecular formula: C22H31N3O5. Mole weight: 417.50.
Comu
Comu. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate;4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate;1-[1-(Cyano-2-ethoxy-2-oxoethylideneaMinooxy)-diMethylaMino-Morpholino]-uroniuM hexafluorophosphate;(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate (This product is only available in Japan.);COMU(R) 97%;elagolix intermediate 13;COMU 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium. Product Category: Heterocyclic Organic Compound. CAS No. 1075198-30-9. Molecular formula: C12H19N4O4.PF6. Mole weight: 0. Product ID: ACM1075198309. Alfa Chemistry ISO 9001:2015 Certified. Categories: Communism.
COMU
COMU is used as an efficient coupling agent in phosphonamidation reactions; used as coupling reagent in the synthesis of solid phase peptide. Synonyms: (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy) dimethylaminomorpholinocarbenium Hexafluorophosphate; (1-Cyano-2-ethoxy-2-oxoethylideneaminooxy)-dimethylamino-morpholino-carbenium hexafluorophosphate; 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate; COMU(R); Elagolix intermediate 13. Grades: > 98 % (HPLC). CAS No. 1075198-30-9. Molecular formula: C12H19F6N4O4P. Mole weight: 428.27.
Labeled (E)-4-Hydroxytoremifene. (E)-4-Hydroxytoremifene is the inactive (E)-isomer of 4-Hydroxy Toremifene. Group: Biochemicals. Alternative Names: (E) -4-[4-Chloro-1-[4-[2-[ (dimethyl-d6) amino]ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; (E)-4-Hydroxytoremifene-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Ensartinib
Ensartinib. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-amino-5-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-N-(4-((3S,5R)-3,5-dimethylpiperazine-1-carbonyl)phenyl)pyridazine-3-carboxamide. CAS No. 1370651-20-9. Molecular Formula: C26H27Cl2FN6O3. Mole Weight: 561.44. Catalog: APB1370651209.
HKI 357 is a potent and irreversible dual inhibitor of ErbB2 (HER2) and EGFR (IC50 = 33 and 34 nM, respectively). It inhibits EGFR autophosphorylation and proliferation of NCI-H1975 cells containing L858R and T790M mutations. Uses: Antitumor agent. Synonyms: HKI 357; HKI357; HKI-357; (2E)-N-[[4-[[(3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide. Grades: ≥98% by HPLC. CAS No. 848133-17-5. Molecular formula: C31H29ClFN5O3. Mole weight: 574.05.
Mono-POM Ethyl Adefovir
An analogue of the antiviral drug Adefovir with a mono-POM ester protecting group. Group: Biochemicals. Alternative Names: Mono (pivaloyloxymethyl) Ethyl Adefovir; 2,2-Dimethylpropanoic Acid [ [ [ [2- (6-amino-9H-purin-9-yl) ethoxy] methyl] ethoxyphosphinyl] oxy] methyl ester. Grades: Highly Purified. CAS No. 142341-04-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Nafcillin Sulfoxide is derived from Nafcillin, a semi-synthetic penicillin antibiotic that is particularly effective against Gram-positive bacteria. Synonyms: 2-Ethoxynaphthylpenicillin Sulfoxide; [2S-(2α,5α,6β)]-6-[[(2-Ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-4-oxide-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, 4-oxide, (2S,5R,6R)-. Grades: 97%. CAS No. 41061-20-5. Molecular formula: C21H22N2O6S. Mole weight: 430.47.
N-(azide-PEG3)-N'-(Amine-C3-PEG4)-Cy5
N-(azide-PEG3)-N'-(Amine-C3-PEG4)-Cy5. Uses: Designed for use in research and industrial production. Product Category: Cyanine Fluorophores. CAS No. 2107273-70-9. Molecular formula: C47H70ClN7O8. Mole weight: 896.6. Purity: 95%+. IUPACName: N-(3-aminopropyl)-3-[2-[2-[2-[2-[2-[5-[1-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-3,3-dimethylindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]propanamide;chloride. Canonical SMILES: CC1(C2=CC=CC=C2[N+](=C1C=CC=CC=C3C(C4=CC=CC=C4N3CCOCCOCCOCCN=[N+]=[N-])(C)C)CCOCCOCCOCCOCCC(=O)NCCCN)C.[Cl-]. Product ID: ACM2107273709-1. Alfa Chemistry ISO 9001:2015 Certified.
Neratinib
Neratinib. Group: Biochemicals. Alternative Names: (2E) -N-[4-[[3-Chloro-4- (2-pyridinylmethoxy) phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4- (dimethylamino) -2-butenamide; HKI 272. Grades: Highly Purified. CAS No. 698387-09-6. Pack Sizes: 10mg. US Biological Life Sciences.
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Neratinib Dimethylamine-N-oxide (M7)
An impurity of Neratinib, which is an irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Synonyms: 2-Butenamide, N-(4-((3-chloro-4-(2-pyridinylmethoxy)phenyl)amino)-3-cyano-7-ethoxy-6-quinolinyl)-4-(dimethyloxidoamino)-, (2E)-. Grades: ≥95%. CAS No. 1376615-55-2. Molecular formula: C30H29ClN6O4. Mole weight: 573.04.
(S)-13-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-14,14-dimethyl-11-oxo-3,6,9-trioxa-12-azapentadecanoic acid. Uses: Designed for use in research and industrial production. Product Category: E3 Ligase Ligand-Linker. CAS No. 2172820-10-7. Molecular formula: C30H42N4O9S. Mole weight: 634.7409. Purity: 0.95. IUPACName: 2-[2-[2-[2-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-2-oxoethoxy]ethoxy]ethoxy]acetic acid. Product ID: PR2172820107. Alfa Chemistry ISO 9001:2015 Certified.
Semaglutide intermediate
Semaglutide intermediate is an intermediate of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: (S)-21,39-di-tert-butyl 1-(2,5-dioxopyrrolidin-1-yl) 9,18,23-trioxo-2,5,11,14-tetraoxa-8,17,22-triazanonatriacontane-1,21,39-tricarboxylate; 17- ( (S) -1-tert-Butoxycarbonyl-3-{2-[2- ({2-[2- (2, 5-dioxopyrrolidin-1-yloxycarbonylmethoxy) ethoxy]ethylcarbamoyl}methoxy) ethoxy]-ethylcarbamoyl}propylcarbamoyl) heptadecanoic acid tert-butyl ester; Octadecanoic acid, 18-[[(1S)-1-[(1,1-dimethylethoxy)carbonyl]-22-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4,13,22-trioxo-8,11,17,20-tetraoxa-5,14-diazadocos-1-yl]amino]-18-oxo-, 1,1-dimethylethyl ester; Bis(2-methyl-2-propanyl) (22S)-1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazatetracontane-22,40-dicarboxylate; tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu. Grades: ≥95%. CAS No. 1118767-15-9. Molecular formula: C47H82N4O15. Mole weight: 943.19.
Suplatast Tosylate
Suplatast Tosylate is an antiallergic drug. Suplatast Tosylate inhibits antigen-induced histamine release from mast cells as well as IgE antibody formation. Suplatast Tosylate suppresses interleukin (IL)-4 release from T cells, however in human peripheral basophils, Suplatast Tosylate inhibited the antigen-induced release of IL-13 but not IL-4. Group: Biochemicals. Alternative Names: [3- [ [4- (3-ethoxy-2-hydroxypropoxy) phenyl] amino] -3-oxopropyl] dimethylsulfonium 4-Methyl Benzene sulfonate; (±) - [2- [4- (3-Ethoxy-2-hydroxypropoxy) phenylcarbamoyl] ethyl] dimethylsulfonium p-toluenesulfonate; IPD 1151T; Suplatast tosilate. Grades: Highly Purified. CAS No. 94055-76-2. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Ticagrelor Related Compound 39
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: N4-((3aS,4R,6R,6aR)-6-(2-((5-amino-6-chloro-2-(propylthio)pyrimidin-4-yl)oxy)ethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)-6-chloro-2-(propylthio)pyrimidine-4,5-diamine. Grades: >95%. Molecular formula: C25H37Cl2N6O4S2. Mole weight: 620.63.
Timolol Impurity E
An impurity of Ticlopidine which has been shown to lower the IOP in normal human volunteers without affecting the pupil size, visual acuity, blood pressure, or pulse rate. Synonyms: (2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]ethoxy]-4-oxobut-2-enoic acid. Grades: > 95%. CAS No. 1026075-53-5. Molecular formula: C17H26N4O6S. Mole weight: 414.48.
Vedroprevir
Vedroprevir is a selective hepatitis C virus (HCV) NS3 protease inhibitor. It is a pharmaceutical drug that is used in the treatment of hepatitis C virus in patients with HCV genotype 1(GT1) infection. It inhibits an important viral phosphoprotein, NS5A, which is involved in viral replication, assembly, and secretion. It retained wild-type activity against multiple classes of NS5B and NS5A inhibitor resistance mutations. It showed good oral bioavailability in all three species tested. It was developed by Gilead Sciences and was terminated in clinic phase 2 trials. Uses: Vedroprevir is a pharmaceutical drug that is used in the treatment of hepatitis c virus in patients with hcv genotype 1(gt1) infection. Synonyms: GS9451; GS-9451; GS 9451; Vedroprevir; (1R,2R)-N-[[(1alpha,3beta,5alpha)-Bicyclo[3.1.0]hex-3-yloxy]carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-chloro-2-[2-[(1-methylethyl)amino]-4-thiazolyl]-7-[2-(4-morpholinyl)ethoxy]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethyl-cyclopropanecarboxylic acid;GS9451;GS-9451;(1R,2R)-1-((2S,4R)-1-((2S)-2-(((((1R,5S)-bicyclo[3.1.0]hexan-3-yl)oxy)carbonyl)amino)-3,3-dimethylbutanoyl)-4-((8-chloro-2-(2-(isopropylamino)thiazol-4-yl)-7-(2-morpholinoethoxy)quinolin-4-yl)oxy)pyrrolidine-2-carboxamido)-2-ethylcyclopropane-1-carboxylic acid. Grades: >98%. CAS No. 1098189-15-1. Molecular formula: C45H60ClN7O9S. Mole weight: 910.52.
Vilanterol Impurity 1
An impurity of Vilanterol. Vilanterol is a relatively selective, long-acting β2-adrenergic agonist as a bronchodilator used for the treatment of COPD and asthma. Synonyms: (1R) -2-[[6-[2-[ (2, 6-Dichlorobenzyl) oxy]ethoxy]hexyl]amino]-1- (2, 2-dimethyl-4H-1, 3-benzodioxin-6-yl) ethanol; (α R) -α -[[[6-[2-[ (2, 6-Dichlorophenyl) methoxy]ethoxy]hexyl]amino]methyl]-2, 2-dimethyl-4H-1, 3-benzodioxin-6-methanol. CAS No. 503068-37-9. Molecular formula: C27H37Cl2NO5. Mole weight: 526.51.
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