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| Product | Description | |
|---|---|---|
| DOTA | Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and therapeutic radiopharmaceuticals. Group: Biochemicals. Alternative Names: 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid; 1,4,7,10-Tetra(carboxymethyl)-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid; DOTA; NSC 681107; Tetraxetan. Grades: Highly Purified. CAS No. 60239-18-1. Pack Sizes: 100mg, 250mg, 500mg. US Biological Life Sciences. |  Worldwide |
| DOTA(allyl ester)3 | DOTA(allyl ester)3, a protected DOTA derivative, is used for coupling to acid- or base-sensitive compounds. Synonyms: DOTA(OAll)3; 4,7,10-Tri-(allyloxycarbonylmethyl)-1,4,7,10-tetraazacyclododecan-1-yl-acetic acid; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7-triallyl ester; 2-(4,7,10-tris(2-(allyloxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; {4,7,10-Tris[2-(allyloxy)-2-oxoethyl]-1,4,7,10-tetraazacyclododecan-1-yl}acetic acid. Molecular formula: C25H40N4O8. Mole weight: 524.61. |  |
| DOTA-Biotin-Sarcosine | DOTA-Biotin-Sarcosine. Synonyms: [3aS-[3aα,4β(R*),6aα]]-2-[[4-[[[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]methylamino]acetyl]amino]phenyl]methyl]-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid. CAS No. 180978-54-5. Molecular formula: C36H54N8O11S. Mole weight: 806.93. | |
| DOTA derivative | DOTA derivative is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. Synonyms: DOTA derivative. Grade: >98%. CAS No. 153777-70-9. Molecular formula: C43H50N4O8S4. Mole weight: 879.14. | |
| DOTA-Lanreotide | An impurity of Lanreotide. Lanreotide is a synthetic somatostatin analogue used primarily to treat conditions related to excessive hormone production, such as acromegaly and neuroendocrine tumors. Synonyms: L-Threoninamide, 3-(2-naphthalenyl)-N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2→7)-disulfide; DOTA-BIM 23014; DOTA-LAN; DOTA-D-2Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7); DOTA-3-(2-naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide (2->7)-disulfide. Grade: ≥95%. CAS No. 213187-44-1. Molecular formula: C70H95N15O17S2. Mole weight: 1482.73. | |
| DOTA-LM3 | DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. DOTA-LM3 can be labeled with 177Lu and 68Ga for imaging and detecting tumors. Synonyms: DOTA-Cpa-(D-Cys)-Tyr-[D-Aph(Cbm)]-Lys-Thr-Cys-(D-Tyr)-NH2 [Disulfide Bond (D-Cys)2/Cys7]; DOTA-Cpa-D-Cys-Tyr-D-Aph(Cbm)-Lys-Thr-Cys-D-Tyr-NH2 [Disulfide Bond (D-Cys)2/Cys7]. CAS No. 1192362-32-5. Molecular formula: C69H93ClN16O19S2. Mole weight: 1550.16. | |
| DOTA-LM3 | DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis[1][2]. DOTA-LM3 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 1192362-32-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5126. |  |
| DOTA-NHS-ester | DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 170908-81-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-128890. DOTA-?NHS-ester | |
| DOTA-NOC | DOTA-NOC is a potent chelating agent extensively used in radiopharmaceuticals for the targeted imaging and therapy of neuroendocrine tumors. By combining with diverse radiometals, such as lutetium-177 or yttrium-90, it generates therapeutic agents that specifically bind to neuroendocrine tumor cells. The DOTA-NOC derivatives have displayed remarkable specificity and affinity for somatostatin receptors, endowing it with a unique potential for cancer therapy. Its diverse applications stem from its impressive properties, which include high burstiness in sentence structure and an elevated level of perplexity in its descriptions. Synonyms: L-Cysteinamide, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; DOTA-[Nal3]-octreotide; H-D-Phe(DOTA)-Cys(1)-Nal-D-Trp-Lys-Thr-Cys(1)-Thr-ol; DOTA-D-Phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7)-disulfide. Grade: 95%. CAS No. 619300-53-7. Molecular formula: C69H94N14O17S2. Mole weight: 1455.70. | |
| DOTAP chloride | ?98% (TLC), powder. Group: Fluorescence/luminescence spectroscopy. |  |
| DOTAP chloride | DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1,2-Dioleoyl-3-trimethylammonium-propane chloride. CAS No. 132172-61-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-112754A. | |
| DOTAP:Chol (50:50) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. |  |
| DOTAP:Chol:DOPE (10:75:5) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:Chol:PEG2000 (65:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC (1:99)-ATP Liposome | This product is a positively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC (20:80)-ATP Liposome | This product is a positively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC (5:95)-ATP Liposome | This product is a positively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (10:55:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (1:64:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (20:45:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (2.5:62.5:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (30:35:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (40:25:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (50:15:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (5:60:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPC:Chol:PEG2000 (60:5:30:5)-ATP Liposome (PEGylated) | This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP:DOPE (50:50) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTA-PEG5-azide | DOTA-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DOTA-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140752. | |
| DOTA-PEG5-azide | DOTA-PEG5-azide is a polyethylene glycol (PEG)-based PROTAC linker. DOTA-PEG5-azide can be used in the synthesis of a series of PROTACs. Synonyms: DOTA-PEG5-C2-azide. Grade: 95%. Molecular formula: C28H52N8O12. Mole weight: 692.76. | |
| DOTA-PEG5-C6-DBCO | DOTA-PEG5-C6-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DOTA-PEG5-C6-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-140314. | |
| DOTAP Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| DOTAP mesylate | DOTAP mesylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 252769-92-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W127426. | |
| DOTAP methylsulfate | DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate. CAS No. 144189-73-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg. Product ID: HY-W127378. | |
| DOTAP:PC:Chol (10:60:30)-ATP Liposome | This product is a positively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| Dotarizine | Dotarizine. Group: Biochemicals. Alternative Names: 1-(Diphenylmethyl)-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]piperazine; FI-6026. Grades: Highly Purified. CAS No. 84625-59-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C29H34N2O2. US Biological Life Sciences. | Worldwide |
| Dotarizine (1-(Diphenylmethyl)-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]piperazine, FI-6026) | Antimigraine. Group: Biochemicals. Alternative Names: 1-(Diphenylmethyl)-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]piperazine; FI-6026. Grades: Highly Purified. CAS No. 84625-59-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| DOTATATE | DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) [1] [2] [3] [4]. DOTATATE can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 177943-88-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-106244. | |
| DOTATATE | DOTATATE is a radiolabeled somatostatin analog used in medical imaging and therapy for neuroendocrine tumors (NETs). DOTATATE is a peptide derivative that binds selectively to somatostatin receptors (mainly subtype 2), which are overexpressed on the surface of neuroendocrine tumor cells. This allows for specific targeting of these tumors. Synonyms: L-Threonine, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide; L-Threonine, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide; DOTA-octreotate; DOTA-TATE; DOTA-[Tyr3]-Octreotide Acid; DOTA-(Tyr3)-octreotate. Grade: ≥95%. CAS No. 177943-88-3. Molecular formula: C65H90N14O19S2. Mole weight: 1435.63. | |
| DOTATATE acetate | DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) [1] [2] [3] [4]. DOTATATE (acetate) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 177943-89-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106244A. | |
| DOTATATE acetate | DOTATATE acetate is a radiolabeled somatostatin analog used in medical imaging and therapy for neuroendocrine tumors (NETs). DOTATATE acetate is a peptide derivative that binds selectively to somatostatin receptors (mainly subtype 2), which are overexpressed on the surface of neuroendocrine tumor cells. This allows for specific targeting of these tumors. Synonyms: L-Threonine, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide, acetate (salt) (1:x); DOTA-(Tyr3,Thr8)-Octreotide acetate; DOTA-[Tyr3] Octreotide Acid (Octreotate) acetate; DOTA-octreotate acetate; DOTA-[Tyr3]-Octreotide Acid acetate. Grade: 98%. CAS No. 177943-89-4. Molecular formula: C65H90N14O19S2.xC2H4O2. Mole weight: 1435.63 (free base). | |
| DOTA-tris(tBu)ester NHS ester | DOTA-tris(tBu)ester NHS ester is a derivative of DOTA for the labeling of peptides and antibodies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 819869-77-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-131326. | |
| DOTA-tris(tert-butyl ester) | It is the PDC linker targeting moietie of peptide drug conjugates (PDCs). Synonyms: Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate; DOTA tri(tert-butyl) ester; DOTA(OBu-t)3; Tri-tert-Bu-DOTA; 2-(4,7,10-Tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; DOTA(OtBu); 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1,4,7-tris(1,1-dimethylethyl) ester; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tris(1,1-dimethylethyl) ester; 1,4,7,10-Tetraazacyclododecane-1,4,7-tris-tert-butyl acetate-10-acetic acid. Grade: 95%. CAS No. 137076-54-1. Molecular formula: C28H52N4O8. Mole weight: 572.73. | |
| DOTA-tri(t-butyl ester) | DOTA-tri(t-butyl ester) can be used in the synthesis of generations 3 (G3) nanoglobular magnetic resonance imaging (MRI) contrast agents for MR angiography and tumor angiogenesis imaging [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 137076-54-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W034551. | |
| 0.5% DiI Encapsulated DOTAP Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| 0.5% DiO Encapsulated DOTAP Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| 0.5% NBD-DOPE Encapsulated DOTAP:Chol (50:50) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| 0.5% NBD-DOPE Encapsulated DOTAP:Chol:DOPE (10:75:5) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| 0.5% NBD-DOPE Encapsulated DOTAP:DOPE (50:50) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| 0.5% Rhod-PE Encapsulated DOTAP:Chol (50:50) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| 0.5% Rhod-PE Encapsulated DOTAP:Chol:DOPE (10:75:5) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| 0.5% Rhod-PE Encapsulated DOTAP:DOPE (50:50) Liposomes | Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| 10-Descarboxymethyl-10-[2-[ (diphosphonomethyl) amino) -2-oxoethyl]-DOTA | 10-Descarboxymethyl-10-[2-[ (diphosphonomethyl) amino) -2-oxoethyl]-DOTA is used in the preparation and biodistribution assessment of 111n-BPAMD as novel agent for bone SPECT imaging. Group: Biochemicals. Grades: Highly Purified. CAS No. 872469-60-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H33N5O13P2, Molecular Weight: 577.419999999999. US Biological Life Sciences. | Worldwide |
| 3-Azidopropyl thioureidobenzyl DOTA | 3-Azidopropyl thioureidobenzyl DOTA is a bifunctional molecule, which can be conjugated to monoclonal antibody (mAb) and also chelate metal ion for radioimmunotherapy and PET imaging (immuno-PET). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C27H41N9O8S, Molecular Weight: 651.73. US Biological Life Sciences. | Worldwide |
| [DOTA-(Bn-pSCN)], pHLIP var3 (D) | [DOTA-(Bn-pSCN)], pHLIP var3 (D) is a derivative of pHLIP var3, a pH low insertion peptide used as a marker of low pH in tumor allografts and of malignant lesions. Synonyms: DOTA-(Bn-pSCN)-D-Ala-D-Cys-D-Asp-D-Asp-D-Gln-D-Asn-D-Pro-D-Trp-D-Arg-D-Ala-D-Tyr-D-Leu-D-Asp-D-Leu-D-Leu-D-Phe-D-Pro-D-Thr-D-Asp-D-Thr-D-Leu-D-Leu-D-Leu-D-Asp-D-Leu-D-Leu-D-Trp; DOTA-(Bn-pSCN)-Ala-Cys-Asp-Asp-Gln-Asn-Pro-Trp-Arg-Ala-Tyr-Leu-Asp-Leu-Leu-Phe-Pro-Thr-Asp-Thr-Leu-Leu-Leu-Asp-Leu-Leu-Trp (All D AA). Mole weight: 3773.43. | |
| [DOTA-(Bn-pSCN)], pHLIP var7 (D) | [DOTA-(Bn-pSCN)], pHLIP var7 (D) is a derivative of pHLIP var7, which is the shortest and most polar peptide sequence in the pHLIP family targeting the tumor. Synonyms: DOTA-(Bn-pSCN)-D-Ala-D-Cys-D-Glu-D-Glu-D-Gln-D-Asn-D-Pro-D-Trp-D-Ala-D-Arg-D-Tyr-D-Leu-D-Glu-D-Trp-D-Leu-D-Phe-D-Pro-D-Thr-D-Glu-D-Thr-D-Leu-D-Leu-D-Leu-D-Glu-D-Leu; DOTA-(Bn-pSCN)-Ala-Cys-Glu-Glu-Gln-Asn-Pro-Trp-Ala-Arg-Tyr-Leu-Glu-Trp-Leu-Phe-Pro-Thr-Glu-Thr-Leu-Leu-Leu-Glu-Leu (All D AA). Mole weight: 3617.2. | |
| [DOTA-(Bn-pSCN)], pHLIP WT (D) | [DOTA-(Bn-pSCN)], pHLIP WT (D) is a derivative of pHLIP-WT, a pH low insertion peptide used as a marker of low pH in tumor allografts and of malignant lesions. Synonyms: DOTA-(Bn-pSCN)-D-Ala-D-Cys-D-Glu-D-Gln-D-Asn-D-Pro-D-Ile-D-Tyr-D-Trp-D-Ala-D-Arg-D-Tyr-D-Ala-D-Asp-D-Trp-D-Leu-D-Phe-D-Thr-D-Thr-D-Pro-D-Leu-D-Leu-D-Leu-D-Leu-D-Asp-D-Leu-D-Ala-D-Leu-D-Leu-D-Val-D-Asp-D-Ala-D-Asp-D-Glu-D-Gly-D-Thr; DOTA-(Bn-pSCN)-Ala-Cys-Glu-Gln-Asn-Pro-Ile-Tyr-Trp-Ala-Arg-Tyr-Ala-Asp-Trp-Leu-Phe-Thr-Thr-Pro-Leu-Leu-Leu-Leu-Asp-Leu-Ala-Leu-Leu-Val-Asp-Ala-Asp-Glu-Gly-Thr (All D AA). Mole weight: 4663.4. | |
| Europium DOTA Sodium Salt Hydrate | Bifunctional DOTA derivatives and their conjugation to peptides has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and therapeutic radiopharmaceuticals. Group: Biochemicals. Alternative Names: 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid Europium Sodium Salt Hydrate; Europium 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic Acid Sodium Salt Hydrate; Eu-DOTA; NSC 681107-Eu; Eu-Tetraxetan Sodium Salt Hydrate. Grades: Highly Purified. CAS No. Free Acid: 60239-18-1. Pack Sizes: 10mg. Molecular Formula: C??H??EuN?NaO? xH?O. US Biological Life Sciences. | Worldwide |
| Fluorescein-triazole-PEG5-DOTA | Fluorescein-triazole-PEG5-DOTA. Uses: For industrial and laboratory use. Product Category: Fluorescein-PEG. Molecular formula: C67H79N11O18S. Mole weight: 1358.5 g/mol. Purity: 0.98. Product ID: DYE-FLU-0079. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Fluorescent DOTAP | Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ?463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research[1][3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: NBD-DOTAP. CAS No. 1010076-97-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-143702. | |
| Iron DOTA Sodium Salt Pentahydrate | Fe(III) complexes of macrocyclic amino carboxylates. Group: Biochemicals. Alternative Names: Sodium (TPS-7-2-134542)-[1, 4, 7, 10-Tetraazacyclododecane-1, 4, 7, 10-tetraacetato(4-)-N1, N4, N7, N10, O1, O4, O7]ferrate(1-). Grades: Highly Purified. CAS No. 149819-85-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Lys40(DOTA), Exendin-4 | Lys40(DOTA), Exendin-4. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-Lys(DOTA)-NH2. Mole weight: 4701.45. | |
| Maleimide-DOTA | Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Maleimido-mono-amide-DOTA. CAS No. 1006711-90-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-133540. | |
| NMe-D-Orn(AMBS-DOTA)2, CPCR4-2 | NMe-D-Orn(AMBS-DOTA)2, CPCR4-2. Molecular formula: C60H80N14O14. Mole weight: 1318.57. | |
| p-SCN-Bn-DOTA | p-SCN-Bn-DOTA is a bifunctional chelating agent. p-SCN-Bn-DOTA can simultaneously chelate radionuclides and link monoclonal antibody for radioimmunoresearch of tumor[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 127985-74-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114377. | |
| p-SCN-Bn-DOTA | p-SCN-Bn-DOTA is an impurity of Gadoteridol, which is a gadolinium-based MRI contrast agent used in central nervous system imaging. Synonyms: 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 2-[(4-isothiocyanatophenyl)methyl]-; 2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid; 2,2',2'',2'''-[2-(4-Isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl]tetraacetic acid; S-2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane tetraacetic acid; Gadobutrol Impurity 33. Grade: 98%. CAS No. 127985-74-4. Molecular formula: C24H33N5O8S. Mole weight: 551.61. | |
| (S)-p-SCN-Bn-DOTA | (S)-p-SCN-Bn-DOTAis a bifunctional chelator ( Bifunctional Chelator ; BFC ) and a macrocyclic DOTA derivative used for tumor pre-targeting. (S)-p-SCN-Bn-DOTA can be used for conjugation of peptides and radionuclides. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1020407-41-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156038. | |
| 1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt) | 1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt) is a liposome formulation for cationic lipid DOTAP. DOTAP can be used for the efficiency of DNA transfection, including yeast artificial chromosomes (YAC) transfection to eukaryotic cells used in transient or stable gene expression, and also suitable for efficient will other negatively charged molecules, such as RNA, oligonucleotides, and glutamic acid, the ribosome protein (RNP) complex, and protein, transferred to the study sample of mammalian cells. Synonyms: DOTAP Transfection Reagent; DOTAP-MS; N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium methyl sulfate; DOTAP methosulfate; 18:1 TAP (DOTAP, MS Salt); n-(2,3-dioleoyloxy-1-propyl) trimethylammonium methyl sulfate. Grade: 98%. CAS No. 144189-73-1. Molecular formula: C43H83NO8S. Mole weight: 774.19. | |
| 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid | 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid. Uses: Bifunctional dota aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted mri contrast agents and diagnostic and ther apeutic radiopharmaceuticals. Group: Macrocyclessupramolecular host materials. Alternative Names: J-650232; AJ-80871; MFCD00068657; CHEBI:61028; LS-187777; CS-0046228; 2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid; ZINC22059268; BCP13075; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid Europium. CAS No. 60239-18-1. Product ID: 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid. Molecular formula: 404.42g/mol. Mole weight: C16H28N4O8. C1CN (CCN (CCN (CCN1CC (=O)O)CC (=O)O)CC (=O)O)CC (=O)O. InChI=1S/C16H28N4O8/c21-13 (22)9-17-1-2-18 (10-14 (23)24)5-6-20 (12-16 (27)28)8-7-19 (4-3-17)11-15 (25)26/h1-12H2, (H, 21, 22) (H, 23, 24) (H, 25, 26) (H, 27, 28). WDLRUFUQRNWCPK-UHFFFAOYSA-N. |  |
| DO3A tert-Butyl ester | DOTA tert-Butyl ester is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. Synonyms: Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7-triacetate; DO3A-t-Bu-ester; 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Tri-tert-butyl Ester. Grade: >98%. CAS No. 122555-91-3. Molecular formula: C26H50N4O6. Mole weight: 514.70. | |
| DPI-4452 | DPI-4452 is a CAIX -targeting cyclic peptide with a DOTA cage, and can be chelated with radionuclide for CAIX-expressing tumor PET-CT imaging and study. DPI-4452 specifically and selectively binds CAIX without interaction with an in vitro off-target receptor panel of 55 targets ( IC 50 for recombinant hCAIX: 130 nM). Radiolabeled DPI-4452 inhibits tumor growth in HT-29 and SK-RC-52 xenograft mouse models [1]. DPI-4452 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 2941391-49-5. Pack Sizes: 1 mg. Product ID: HY-P10761. | |
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