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| Product | Description | |
|---|---|---|
| E 2012 | E 2012 is a potent gamma (γ) secretase modulator without affecting Notch processing. E 2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induces cataract following repeated doses in the rat [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 870843-42-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 100 mg. Product ID: HY-10016. |  |
| E 2012 | E 2012, is a potent selective, orally bioavailable γ-secretase modulator without affecting Notch processing that can used to treat Alzheimer's Disease. Synonyms: (3E)-1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]piperidin-2-one; 870843-42-8; E 2012; (E)-1-[(1S)-1-(4-FLUOROPHENYL)ETHYL]-3-[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)BENZYLIDENE]PIPERIDIN-2-ONE; UNII-3LSD4Y5F0F; 3LSD4Y5F0F; CHEMBL1224151; E-2012; (e)-1-((1s)-1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1h-imidazol-1-yl)benzylidene)piperidin-2-one; (3E)-1-((1S)-1-(4-Fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene)piperidin-2-one; (3E)-1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]piperidin-2-one; GTPL7358; SCHEMBL1238634; SCHEMBL1238639; C25H26FN3O2; DTXSID30468614; PUOAETJYKQITMO-LANLRWRYSA-N; (S,E)-1-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene)piperidin-2-one; W-5462; J-501810; I14-15434; (3E)-1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylene]piperidin-2-one; 2-Piperidinone, 1-((1S)-1-(4-fluorophenyl)ethyl)-3-((3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)methylene)-, (3E)-. CAS No. 870843-42-8. Molecular formula: C25H26FN3O2. Mole weight: 419.49. |  |
| 1,2-Pyrrolidinedicarboxylicacid,2-(1,1-dimethylethyl)1-(phenylmethyl)ester,(2R)- | 1,2-Pyrrolidinedicarboxylicacid,2-(1,1-dimethylethyl)1-(phenylmethyl)ester,(2R)-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Z-D-proline t-butyl ester, AC1OC39Y, CTK8E9769, 16881-39-3, L-Proline tert-butyl ester, N-CBZ protected, 1-benzyl 2-tert-butyl (2R)-pyrrolidine-1,2-dicarboxylate, 1-O-benzyl 2-O-tert-butyl (2R)-pyrrolidine-1,2-dicarboxylate, tert-Butyl (2S)-1-[(Benzyloxy)carbonyl]pyrrolidine-2-carboxylate, 201206-00-0. Product Category: Heterocyclic Organic Compound. CAS No. 201206-00-0. Molecular formula: C17H23NO4. Mole weight: 305.37. Purity: 0.96. IUPACName: 1-O-benzyl 2-O-tert-butyl (2R)-pyrrolidine-1,2-dicarboxylate. Canonical SMILES: CC(C)(C)OC(=O)C1CCCN1C(=O)OCC2=CC=CC=C2. Product ID: ACM201206000. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 1-(4-Benzyloxy-3-methoxyphenyl)ethanone | Intermediate in the preparation of Epinephrine metabolites. Group: Biochemicals. Alternative Names: 1-[3-Methoxy-4- (phenylmethoxy) phenyl]ethanone; 4'-(Benzyloxy)-3'-methoxy-acetophenone; Acetovanillone benzyl ether; NSC 201234. Grades: Highly Purified. CAS No. 1835-11-6. Pack Sizes: 500mg. US Biological Life Sciences. |  Worldwide |
| 1-Boc-5-bromoindole-3-boronic acid pinacol ester | 1-Boc-5-bromoindole-3-boronic acid pinacol ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1024677-85-7, TERT-BUTYL 5-BROMO-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE-1-CARBOXYLATE, SureCN9904358, CTK4A1121, MolPort-015-143-963, ANW-53526, AKOS015834576, AG-L-20125, AK-91926, BD230099, KB-61285, A-3799, 1-Boc-5-bromoindole-3-boronic acid pinacol ester. Product Category: Heterocyclic Organic Compound. CAS No. 1024677-85-7. Molecular formula: C19H25BBrNO4. Mole weight: 422.1. Purity: 0.95. IUPACName: tert-butyl 5-bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole-1-carboxylate. Canonical SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CN(C3=C2C=C(C=C3)Br)C(=O)OC(C)(C)C. Product ID: ACM1024677857. Alfa Chemistry ISO 9001:2015 Certified. | |
| (2S, 3S, 3''S) -N- [3- (3-Acetoxy-3-methoxycarbonyl propanamido) -3-tert-butoxycarbonyl propanoyl ] azetidine-2-carboxyl ic acid tert-butyl ester | (2S, 3S, 3''S) -N- [3- (3-Acetoxy-3-methoxycarbonyl propanamido) -3-tert-butoxycarbonyl propanoyl ] azetidine-2-carboxyl ic acid tert-butyl ester. Group: Biochemicals. Alternative Names: (a-S, 2S) -a-[[ (3S) -3- (Acetyloxy) -4-methoxy-1, 4-dioxobutyl]amino]-2-[ (1, 1-dimethylethoxy) carbonyl]-gamma-oxo-1-azetidinebutanoic acid 1,1-dimethylethyl ester. Grades: Highly Purified. CAS No. 201283-56-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C23H36N2O10. US Biological Life Sciences. | Worldwide |
| (2S, 3S, 3''S) -N- [3- (3-Acetoxy-3-methoxycarbonyl propanamido) -3-tert-butoxythiocarbonyl propanoyl ] azetidine-2-thiocarboxyl ic acid tert-butyl ester | (2S, 3S, 3''S) -N- [3- (3-Acetoxy-3-methoxycarbonyl propanamido) -3-tert-butoxythiocarbonyl propanoyl ] azetidine-2-thiocarboxyl ic acid tert-butyl ester. Group: Biochemicals. Alternative Names: (a-S, 2S) -a-[[ (3S) -3- (Acetyloxy) -4-methoxy-4-oxo-1-thioxobutyl]amino]-2-[ (1, 1-dimethylethoxy) carbonyl]-gamma-thioxo-1-azetidinebutanoic acid. Grades: Highly Purified. CAS No. 201283-57-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C23H36N2O8S2. US Biological Life Sciences. | Worldwide |
| 4-PPBP maleate | 4-PPBP maleate is a potent σ 1 receptor ligand and agonist. 4-PPBP maleate is a non-competitive, selective NR1a/2B NMDA receptors (expressed in Xenopus oocytes ) antagonist. 4-PPBP maleate provides neuroprotection [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 201216-39-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101043. | |
| 5-Chloro-4-nitro-O-toluidine 40% | 5-Chloro-4-nitro-O-toluidine 40%. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-Chloro-4-nitro-o-toluidine, 6-Chloro-4-nitro-o-toluidine, 201200_ALDRICH, 5-Chloro-2-methyl-4-nitroaniline, NSC60116, 2-Amino-4-chloro-5-nitrotoluene, 3-Chloro-6-methyl-4-nitroaniline, CID83772, EINECS 237-589-0, SBB003702, 13852-51-2, InChI=1/C7H7ClN2O2/c1-4-2-7(10(11)12)5(8)3-6(4)9/h2-3H,9H2,1H. Product Category: Amines. Appearance: Yellow crystal or powder. CAS No. 13852-51-2. Molecular formula: C7H7ClN2O2. Mole weight: 186.6. Purity: 0.99. IUPACName: 5-chloro-2-methyl-4-nitroaniline. Canonical SMILES: CC1=CC(=C(C=C1N)Cl)[N+](=O)[O-]. Density: 1.415 g/cm³. ECNumber: 237-589-0. Product ID: ACM13852512. Alfa Chemistry ISO 9001:2015 Certified. | |
| 6-Methoxy-2-naphthoic acid | 6-Methoxy-2-naphthoic acid is an NMDA receptor modulator extracted from patent WO 2012019106 A2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Naproxen impurity O. CAS No. 2471-70-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B2121. | |
| A-75943 | A-75943 is is a bone resorption inhibitor produced by Streptomyces sp. SANK61296. In vitro tests, it has the effect of inhibiting bone resorption with IC50 of 0.35 μmol/L. It also inhibits the bone resorption in rats with thyroid and parathyroidectomy. Synonyms: 2H-Pyran-4-acetamide, 2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)tetrahydro-6-oxo-, (2R,4S)-. Grades: >98%. CAS No. 201215-10-3. Molecular formula: C15H23NO4. Mole weight: 281.35. | |
| Alpha-Isopropyl-4-Chlorophenylacetic Acid | Alpha-Isopropyl-4-Chlorophenylacetic Acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-(p-Chlorophenyl)-3-methylbutyric acid; 4-Chloro-alpha-(1-Methylethyl)-Benzeneacetic Acid; Alpha-Isopropyl-4-Chlorophenylacetic Acid; 2-(4-chlorophenyl)-3-methylbutanoic acid; 2-(4-chlorophenyl)isovaleric acid; 2-(4-Chlorophenyl)-3-methylbutyric acid; EI. Product Category: Heterocyclic Organic Compound. CAS No. 2012-74-0. Molecular formula: C11H13ClO2. Mole weight: 212.67. Purity: 0.96. IUPACName: 2-(4-chlorophenyl)-3-methylbutanoic acid. Canonical SMILES: CC(C)C(C1=CC=C(C=C1)Cl)C(=O)O. Density: 1.184g/cm³. ECNumber: 217-934-1. Product ID: ACM2012740. Alfa Chemistry ISO 9001:2015 Certified. | |
| Atopaxar | Atopaxar is a Protease-activated receptor-1 (PAR-1) inhibitor. It can inhibit the binding of a high-affinity thrombin receptor-activating peptide ([(3)H]haTRAP) to PAR-1 with IC50 value of 0.019μM. Atopaxar exhibits potent inhibitory effects on human platelet aggregation induced by thrombin and TRAP with IC50 values of 0.064 and 0.031μM. It may become a therapeutic option for atherothrombotic disease. In May 2012, Phase-II for Acute coronary syndromes in European Union was discontinued. Uses: Acute coronary syndromes. Synonyms: E5555; E-5555; E 5555; ER-172594-00; ER172594-00; ER 172594-00; Atopaxar;1-(3-(tert-butyl)-4-methoxy-5-morpholinophenyl)-2-(5,6-diethoxy-7-fluoro-1-iminoisoindolin-2-yl)ethan-1-one;474550-69-1(hydrobromide). Grades: 98%. CAS No. 751475-53-3. Molecular formula: C29H38FN3O5. Mole weight: 527.64. | |
| Benzene,ethenyl-,homopolymer,isotactic | Benzene,ethenyl-,homopolymer,isotactic. Uses: Designed for use in research and industrial production. Additional or Alternative Names: LATEX;'LGC' (2012);STYRENE LATEX;STYRENE POLYMER;STYRENE RESIN;PS RESIN;POLYSTYRENE 10'000;POLYSTYRENE 100'000. Product Category: Heterocyclic Organic Compound. CAS No. 25086-18-4. Molecular formula: C8H8. Density: 1.06 g/mL at 25 °C. Product ID: ACM25086184. Alfa Chemistry ISO 9001:2015 Certified. | |
| Beraprost | Beraprost is a synthetic analogue of prostacyclin, under clinical trials for the treatment of pulmonary hypertension. Beraprost acts by binding to prostacyclin membrane receptors ultimately inhibiting the release of Ca2+ from intracellular storage sites. Beraprost sodium (beraprost) is a stable, orally active prostacyclin analogue with vasodilatory, antiplatelet and cytoprotective effects. Synonyms: Procylin; Careload; Dorner; Beraprost sodium; TRK-100; TRK 100; TRK100; YM-533; YM533; YM 533; ML-1129; ML 1129; ML1129; MDL 201229; MDL-201229; MDL201229. CAS No. 88430-50-6. Molecular formula: C24H30O5. Mole weight: 398.49. | |
| Beraprost Sodium Salt | Platelet aggregation inhibitor; stable analog of Prostacyclin. Antithrombotic; vasodilator (peripheral). Group: Biochemicals. Alternative Names: dl-4- [ (1R, 2R, 3aS, 8bS) -2, 3, 3a, 8b-Tetrahydro-2-hydroxy- [ (3S, 4RS) -3-hydroxy-4-methyl-oct-6-yne- (E) -1-enyl] -5-cyclopenta [b] benzofuranyl] butanoic Acid Sodium; MDL 201229; ML 1229; Dorner; Procylin. Grades: Highly Purified. CAS No. 88475-69-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Bosutinib Isomer Methanoate | Bosutinib Isomer is the 3,5-dichloro-4-methoxy isomer of Bosutinib. It has been reported that this compound has been offered incorrectly as Bosutinib (B676095) C&E News 90 (21) 2012 34-35 and Levinson NM, Boxer SG (2012) Structural and Spectroscopic Analysis of the Kinase Inhibitor Bosutinib and an Isomer of Bosutinib Binding to the Abl Tyrosine Kinase Domain. PLoS ONE 7(4): e29828. doi:10. 1371/journal. pone. 0029828. Group: Biochemicals. Alternative Names: 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile Methanoate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bulevirtide | Bulevirtide (Myrcludex B) is a NTCP inhibitor, a linear lipopeptide of 47 amino acids. Bulevirtide inhibits HBV and HDV entry into liver cells, blocks HBV infection in hepatocytes, and participates in HBV transcriptional suppression. Bulevirtide can be used in HDV infection and compensated cirrhosis research [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Myrcludex B. CAS No. 2012558-47-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P3465. | |
| Cephalexin | Cefalexin, also spelled cephalexin, is an antibiotic that can treat a number of bacterial infections. It kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cefalexin is a beta-lactam antibiotic within the class of first-generation cephalosporins. It works similarly to other agents within this class, including intravenous cefazolin, but can be taken by mouth.Cefalexin can treat certain bacterial infections, including those of the middle ear, bone and joint, skin, and urinary tract. It may also be used for certain types of pneumonia, strep throat, and to prevent bacterial endocarditis. Cefalexin is not effective against infections caused by methicillin-resistant Staphylococcus aureus (MRSA), Enterococcus, or Pseudomonas. Like other antibiotics, cefalexin cannot treat viral infections, such as the flu, common cold or acute bronchitis. Cefalexin can be used in those who have mild or moderate allergies to penicillin. However, it is not recommended in those with severe penicillin allergies.Common side effects include upset stomach and diarrhea. An allergic reaction and infection with Clostridium difficile, a type of diarrhea, is also possible. To date, no evidence of harm to the baby has been found when used during pregnancy or breast feeding. It can be used in children and those over 65 years of age. Those with kidney problems may require a decrease in dose.In 2012, cefalexin wa | |
| Cindunistat hydrochloride maleate | Cindunistat is a selective Nitric oxide synthase (iNOS) type II inhibitor. It is potentially useful in patients with symptomatic osteoarthritis of the knee. But in Feb 2012, Phase-II/III for Osteoarthritis was discontinued. Uses: Osteoarthritis. Synonyms: PHA-728669F; PHA 728669F; PHA728669F; SD-6010; SD 6010; SD6010 PF-00572986; PF00572986; PF 00572986; PF-572986; PF572986; PF 572986; PHA-84250; PHA84250; PHA 84250; SC-084250; SC 084250; SC084250; Cindunistat. cindunistat hydrochloride maleate;(R,Z)-2-amino-3-((2-((1-aminoethylidene)amino)ethyl)thio)-2-methylpropanoic acid compound with maleic acid (2:1) hydrochloride. Grades: 98%. CAS No. 753491-31-5. Molecular formula: C20H39ClN6O8S2. Mole weight: 591.15. | |
| CKD-516 | This active molecular is a tubulin polymerisation inhibitor which is applicated for solid cancer treatment. CKD-516 disruptes tubulin of the endothelial cytoskeleton selectively. In Jun 2012, a South Korea company, Chong Kun Dang initiated enrolment in a phase I trial for solid tumours treatment in South Korea. In Dec 2014, Phase-I clinical trials in Solid tumours in South Korea was on going. Uses: Solid tumours. Synonyms: CKD-516 HCl; CKD 516 HCl; CKD516 HCl; (2S)-2-amino-3-methyl-N-[4-[3-(1,2,4-triazol-1-yl)-4-(3,4,5-trimethoxybenzoyl)phenyl]-1,3-thiazol-2-yl]butanamide;hydrochloride;1188371-47-2 (free base). Grades: 98%. CAS No. 1188371-47-2. Molecular formula: C26H28N6O5S. Mole weight: 536.6. | |
| D-Threonine benzyl ester oxalate | Synonyms: H-D-Thr-OBzl (COOH)2; (2R,3S)-2-Amino-3-hydroxybutanoic acid benzyl ester oxalate. CAS No. 201274-09-1. Molecular formula: C13H17NO7. Mole weight: 299.28. | |
| Elinogrel | Elinogrel, also known as PRT 060128, is P2Y12 inhibitor. Similarly to ticagrelor and in contrast to clopidogrel, elinogrel was a reversible inhibitor that acted fast and short (for about 12 hours), and it was not a prodrug but pharmacologically active itself. The substance was used in form of its potassium salt, intravenously for acute treatment and orally for long-term treatment. Development was terminated in 2012. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PRT 060128; PRT-060128; PRT060128; Elinogrel. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 936500-94-6. Molecular formula: C20H15ClFN5O5S2. Mole weight: 523.94. Purity: >98%. IUPACName: 5-chloro-N-((4-(6-fluoro-7-(methylamino)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)phenyl)carbamoyl)thiophene-2-sulfonamide. Canonical SMILES: O=C(NC1=CC=C(N2C(NC3=C(C=C(F)C(NC)=C3)C2=O)=O)C=C1)NS(=O)(C4=CC=C(Cl)S4)=O. Product ID: ACM936500946-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Epetraborole HCl | This active molecular is a selective leucyl-tRNA synthetase inhibitor under the development of Anacor Pharmaceuticals and GlaxoSmithKline as a novel boron-containing antibiotic. Epetraborole was applicated in treatment of infections caused by multidrug-resistant Gram-negative pathogens. All Clostridium perfringens strains had Epetraborole MICs of >32 μg/ml. In Oct 2012, Phase-II for Urinary tract infections in Russia was discontinued. In Mar 2013, Phase-II for Gram-negative infections in USA was Suspended. Uses: Urinary tract infections;gram-negative infections. Synonyms: UNII-MM0NZY12FA; MM0NZY12FA;SCHEMBL1980656; CHEMBL3527377;3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol;hydrochloride; AN-3365; GSK-052; AN 3365; GSK 052; AN3365; GSK052. Grades: 98%. CAS No. 1234563-16-6. Molecular formula: C11H17BClNO4. Mole weight: 373.52. | |
| Eriodictyol | Eriodictyol is a flavanone characteristic of lime, found mainly in juice. The glycosylated forms are eriocitrin (bound to a rutinoside) and neoeriocitrin (bound to a neohesperidose). Eriodictyol prevents some secondary effects of diabetes, such as diabetic retinopathy and biochemical changes in plasma (study in rats) (Bucolo et al., 2012). In addition, it has been reported that in in vitro studies, eriodictyol decreases insulin resistance and glucose absorption.Eriodictyol is used in biological studies as natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation. Eriodictyl is extracted from Yerba santa, an herb. The leaf is used to make medicine.Yerba santa is used for respiratory conditions including coughs, colds, tuberculosis, asthma, and chronic bronchitis. It is also used for fever and dry mouth. Some people use it to relieve muscle spasms, to loosen phlegm, and as a tonic. Group: Biochemicals. Alternative Names: (2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one; (2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one; 3',4',5,7-tetrahydroxy-flavanone; (+)-Eriodictyol; (2S)-Eriodictyol; (S)-3',4',5,7-Tetrahydroxyflavanone; 3',4',5,7-Tetrahydroxyflavanone; Huazhongilexone. Grades: Highly Purified. CAS No. 552-58-9. Pack Sizes: 10mg, 20mg, 50mg, 100mg. Molecular Formula: C15H12O6, Molecular Weight: 288.25. US Biological Life Sciences. | Worldwide |
| Fast Red ITR | Fast Red ITR. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Red ITR base, Fast Red ITR Base, Fast Red ITR, Orle Base Fast Red ITR, Azoic Diazo No. 42, Brentamine Fast Red ITR Base, MLS000776114, Azoic diazo component 42, base, N1,N1-Diethyl-4-methoxymetanilamide, 2-Methoxy-5-(diethylsulfamoyl)aniline, 201286_SIAL, NSC50670, EINECS 202-575-5, NSC 50670, ZINC04506033, 2-Methoxy-5-(diethylaminosulfonyl)aniline, C.I. 37150, 2-Methoxyaniline-5-sulfonic acid diethylamide, Metanilamide, N1,N1-diethyl-4-methoxy-, SMR000371124. Product Category: Azoic Dyes. Appearance: White uniform powder. CAS No. 97-35-8. Molecular formula: C11H18N2O3S. Mole weight: 258.34. Purity: biological stain. IUPACName: 3-amino-N,N-diethyl-4-methoxybenzenesulfonamide. Density: 1.205g/cm³. Product ID: ACM97358. Alfa Chemistry ISO 9001:2015 Certified. | |
| GDC-0349 | GDC-0349 is a small molecule anticaner drug candidate, being developed by Genentech. As of July 2012, Genentech has filed phase I trial of GDC-0349 for evaluating the Safety and Tolerability of GDC-0349 in Patients With Locally Advanced or Metastatic Solid Tumors or Non Hodgkin's Lymphoma. Synonyms: GDC-0349; GDC 0349; GDC0349; RG7603. CAS No. 1207360-89-1. Molecular formula: C24H32N6O3. Mole weight: 452.559. | |
| Hexaethylene Glycol | Hexaethylene Glycol is part of a leaf extract (Murdannia Bracteata) which exhibits antioxidant, antimicrobial and anti-cancer properties. It also shows potential application as functional hydraulic fluids. Group: Biochemicals. Alternative Names: 2- [2- [2- [2- [2- (2-Hydroxyethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethanol; 2,2'-[oxybis(oxy-2,1-ethanediyloxy-2,1-ethanediyloxy)]bis Ethanol; Hexagol; Hexaoxyethylene Glycol; NSC 201209. Grades: Highly Purified. CAS No. 2615-15-8. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| L-Threonine benzyl ester oxalate(1:1) | L-Threonine benzyl ester oxalate(1:1). Group: Biochemicals. Grades: Reagent Grade. CAS No. 201274-07-9. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| L-Threonine benzyl ester oxalate(1:1) | Synonyms: L-Thr-OBzl oxalate(1:1); L-threonine benzyl ester oxalate salt; H-Thr-Obzl oxalate; L-Threonine benzyl ester oxalate; benzyl L-threoninate hemioxalate. Grades: ≥ 99% (HPLC). CAS No. 201274-07-9. Molecular formula: C11H15NO3·C2H2O4. Mole weight: 299.30. | |
| m-ACSO2 | m-ACSO2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 10,10'-(Sulfonylbis(3,1-phenylene))bis(9,9-dimethyl-9,10-dihydroacridine). Product Category: Organic Light Emitting Diode (OLED). CAS No. 1477512-43-8. Molecular formula: C42H36N2O2S. Mole weight: 632.81 g/mol. Product ID: ACM1477512438. Alfa Chemistry ISO 9001:2015 Certified. Categories: Macau at the 2012 Summer Paralympics. | |
| Mirabegron | Mirabegron tablets were developed by Astellas Pharmaceuticals, Inc. and launched in Japan on September 16, 2011, and approved by the U.S. Food and Drug Administration (FDA) on June 28, 2012, for the treatment of overactive bladder (OAB) in adults. Mirabella is the first β3-adrenoceptor agonist drug in the class for the treatment of overactive bladder disorder, and its successful launch fills the gap in the treatment of overactive bladder disorder with β-adrenoceptor agonists. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenyl)-2-(2-aminothiazol-4-yl)acetamide;YM-178;MIRABEQRON;2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenyl-ethyl]amino]-ethyl]phenyl]-4-thiazoleacetamide;2-(2-amino-1,3-thiazol-4-yl)-N-(4-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl}phenyl)acetamide. Product Category: Heterocyclic Organic Compound. Appearance: Light yellow to yellow solid. CAS No. 223673-61-8. Molecular formula: C21H24N4O2S. Mole weight: 396.506. Density: 1.313. Product ID: ACM223673618. Alfa Chemistry ISO 9001:2015 Certified. | |
| Mirabegron impurity 002 | An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Synonyms: 4-ethoxy-3-methoxybenzonitrile; 81259-56-5; SCHEMBL6944897; MFCD02256107; AKOS000198357; 4-ETHOXY-3-METHOXY-BENZONITRILE; CS-0319395; Z54794538. Grades: 95%. CAS No. 81259-56-5. Molecular formula: C10H11NO2. Mole weight: 177.20. | |
| MK-0249 | This active molecular is a potent histamine H3 inverse antagonist. Current antipsychotic treatments have little impact on the cognitive deficits associated with schizophrenia. MK-0249 might improve cognitive deficits in patients with schizophrenia in due to promote histamine release that may enhance cognition. In Dec 2006, Phase-II clinical trials in Alzheimer's disease in USA was on going. In Dec 2009, adverse events data from a clinical trial in healthy subjects was presented. In Jun 2012, Pharmacodynamics data from a phase I trial in Sleep apnoea syndrome was reported by Merck. Uses: Alzheimer's disease; attention-deficit hyperactivity disorder; obesity; schizophrenia; sleep apnoea syndrome. Synonyms: MK0249; MK 0249; MK-0249; 2-methyl-3-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-5-(trifluoromethyl)quinazolin-4-one. Grades: 98%. CAS No. 1167574-41-5. Molecular formula: C23H24F3N3O2. Mole weight: 431.45. | |
| MUT056399 | MUT056399 is an antibacterial especially against S. aureus and E. coli. It has not been reporte a clinical trial after presenting the preclinical trial data in 2012 yet. IC50: 12 nM and 58 nM for S. aureus and E. coli respectively. Uses: Mut056399 is an antibacterial especially against s. aureus and e. coli. Synonyms: UNII-B52RPV7VRM; MUT056399; B52RPV7VRM; CHEMBL2178284; FAB001; SCHEMBL1498707. Grades: 98%. CAS No. 1269055-85-7. Molecular formula: C15H13F2NO3. Mole weight: 293.27. | |
| N-Carbobenzoxy-D-proline t-butyl ester | Synonyms: Z-D-Pro-OtBu; (R)-1-Carbobenzoxypyrrolidine-2-carboxylic acid t-butyl ester. Grades: 99%. CAS No. 201206-00-0. Molecular formula: C17H23NO4. Mole weight: 305.37. | |
| NSI-189 | NSI-189 is an experimental drug being studied by Neuralstem, Inc. Research into NSI-189 has been funded by the Defense Advanced Research Projects Agency (DARPA) and the National Institutes of Health (NIH) for the treatment of major depressive disorder. NSI-189 successfully completed a phase 1 clinical trial in 2011 where it was administered to 41 healthy volunteers. A phase 1b clinical trial for treating major depressive disorder in 24 patients started in 2012 and completed in July 2014. The study suggests that there were improvements in the patients' condition when the doses were 40/80 mg per day, but no significant improvements were seen for a higher dosage of 120 mg/day. Neuralstem intends to pursue further clinical trials for a variety of neurological conditions, including major depressive disorder, traumatic brain injury, Alzheimer's disease, post-traumatic stress disorder, stroke, and natural cognitive and memory decline in aging. Uses: For research used only. Synonyms: NSI-189; NSI 189; NSI189. Grades: 98%. CAS No. 1270138-40-3. Molecular formula: C22H30N4O. Mole weight: 366.5. | |
| NYX-2925 | NYX-2925 is an orally active NMDAR modulator. NYX-2925 restores levels of activated Src and Src phosphorylation sites on GluN2A and GluN2B in the mPFC. NYX-2925 shows no effect on CAMKII, and any addictive or sedative/ataxic side effects. NYX-2925 can be used for research of a variety of NMDA receptor-mediated central nervous system disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2012536-16-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135741. | |
| ONO-5334 | NO-5334 is cathepsin K inhibitor Ki values of 0.1 nM for human. It can improve bone strength by preferentially increasing cortical bone mass in ovariectomized rats. ONO-5334 can also inhibit N-terminal and C-terminal collagen crosslinks in serum and urine in postmenopausal women. In Feb 2012, Phase-II for Osteoporosis in European Union was discontinued. Uses: Osteoporosis. Synonyms: ONO-5334; ONO 5334; ONO5334. N-((S)-3-(2-((R,Z)-3,4-dimethylthiazolidin-2-ylidene)hydrazinyl)-2,3-dioxo-1-(tetrahydro-2H-pyran-4-yl)propyl)cycloheptanecarboxamide. Grades: 98%. CAS No. 868273-90-9. Molecular formula: C21H34N4O4S. Mole weight: 438.59. | |
| PF-04991532 | This active molecular is a hepatoselective glucokinase activator that reduces MDG (mean daily glucose), FPG (fasting plasma glucose) and glucose excursion in humans. PF-04991532 may offer glycemic control without inducing hepatic steatosis. PF-04991532 was developed by Pfizer but was discontinued in Phase-II for Type-2 diabetes mellitus in USA in 2012. Uses: Type 2 diabetes mellitus. Synonyms: PF-04991532; PF 04991532; PF04991532; PF-4991532; PF4991532; PF 4991532; UNII-AJ212MS2O2; CHEMBL2165620; AJ212MS2O2; SCHEMBL1711504; BDBM50394681; 6-[[(2S)-3-cyclopentyl-2-[4-(trifluoromethyl)imidazol-1-yl]propanoyl]amino]pyridine-3-carboxylic acid. Grades: 98%. CAS No. 1215197-37-7. Molecular formula: C18H19F3N4O3. Mole weight: 396.37. | |
| Pocapavir | Pocapavir has been found to be an antienterovirus agent that could probably be effctive against enterovirus infections. The Phase-II trial for Poliomyelitis has not been reported yet since 2012. Synonyms: SCH-48973; SCH48973; SCH 48973; V074; V 073; V-073; 1, 3-Dichloro-2- ({4-[ (2-chloro-4-methoxyphenoxy) methyl]benzyl}oxy) benzene; 1[2-chloro-4-methoxy-phenyl-oxymethyl]-4-[2,6-dichloro-phenyl-oxymethyl]-benzene; Benzene,1-[(2-chloro-4-methoxyphenoxy)methyl]-4-[(2,6-dichlorophenoxy)methyl]. Grades: 98%. CAS No. 146949-21-5. Molecular formula: C21H17Cl3O3. Mole weight: 423.71. | |
| Spadin | Spadin is a potent and brain penetrating TREK-1 channel blocker (IC50 = 71 nM) displaying antidepressant activity. Spadin enhances dorsal raphe nucleus 5-HT neurotransmission in mice and induces hippocampal CREB activation and neurogenesis in adult mice. Synonyms: Spadin; 1270083-24-3; Spadin (trifluoroacetate salt); HB5438; AKOS025293510; C96H142N26O22; S-1270083-24-3. CAS No. 1270083-24-3. Molecular formula: C96H142N26O22. Mole weight: 2012.34. | |
| (-)-Terpinen-4-ol | (-)-Terpinen-4-ol can be extracted from Bark Beetle Polygraphus poligraphus [1]. Uses: Scientific research. Group: Natural products. CAS No. 20126-76-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N7927. | |
| Vernakalant | Vernakalant is an drug under regulatory for the treatment for conversion of atrial fibrillation. It blocks atrial potassium channels, thereby prolonging repolarization. It differs from typical class III agents and is more effective at high heart rates. It also slightly blocks the hERG potassium channel, leading to a prolonged QT interval. It also blocks atrial sodium channels. It was initially developed by Cardiome Pharma, and the intravenous formulation was bought for further development by Merck in April 2009. In September 2012, Merck terminated its agreements with Cardiome and has consequently returned all rights of the drug back to Cardiome. The drug (under brand name Brinavess) was approved in Europe on 1 September 2010. An oral formulation underwent Phase II clinical trials between 2005 and 2008. Uses: Vernakalant is an drug under regulatory for the treatment for conversion of atrial fibrillation. it blocks atrial potassium channels, thereby prolonging repolarization. it also slightly blocks the herg potassium channel, leading to a prolonged qt interval. it also blocks atrial sodium channels. Synonyms: Brinavess; RSD1235; (3R) -1-[ (1R, 2R) -2-[2- (3, 4-dimethoxyphenyl) ethoxy]cyclohexyl]pyrrolidin-3-ol. Grades: 95%. CAS No. 794466-70-9. Molecular formula: C20H31NO4. Mole weight: 349.47. | |
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