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Product | Description | |
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1-Naphthyl b-D-glucuronide sodium salt Quick inquiry Where to buy Suppliers range | 1-Naphthyl b-D-glucuronide sodium salt, an invaluable biomedicine, is employed extensively in scientific research to explore the intricate process of glucuronidation, which plays a vital role in the metabolism and elimination of a diverse array of pharmaceuticals and endogenous compounds. Acting as a versatile substrate, it facilitates the activities of glucuronosyltransferases, crucial enzymes that mediate glucuronidation reactions. Demonstrating immense utility in in vitro experiments, this product enables scientists to unravel the profound impact of glucuronidation on drug pharmacokinetics, while simultaneously facilitating the evaluation of potential drug-drug interactions. Synonyms: 1-Nap-b-D-GlcA.Na. CAS No. 83833-12-9. Molecular formula: C16H15NaO7. Mole weight: 342.28. | |
(24S)-24,25-Epoxycholesterol Quick inquiry Where to buy Suppliers range | (24S)-24,25-Epoxycholesterol is a derivative of 4 β-Hydroxy Cholesterol (H917980), a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Group: Biochemicals. Grades: Highly Purified. CAS No. 77058-74-3. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C27H44O2, Molecular Weight: 400.64. US Biological Life Sciences. | Worldwide |
25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt Quick inquiry Where to buy Suppliers range | 25-Hydroxy-cholesterol 3-Sulfate Ester is a derivative of 4 β-Hydroxy Cholesterol (H917980), a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Group: Biochemicals. Grades: Highly Purified. CAS No. 1174047-40-5. Pack Sizes: 1mg. Molecular Formula: C27H45NaO5S, Molecular Weight: 504.7. US Biological Life Sciences. | Worldwide |
25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt-d6 Quick inquiry Where to buy Suppliers range | 25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt-d6 is the isotope labelled analog of 25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt (H825760). 25-Hydroxy-cholesterol 3-Sulfate Ester is a derivative of 4 β-Hydroxy Cholesterol (H917980), a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C27H39D6NaO5S, Molecular Weight: 510.73. US Biological Life Sciences. | Worldwide |
2-Methylcitric Acid Quick inquiry Where to buy Suppliers range | 2-Methylcitric Acid is a metabolite of Citric Acid. It is formed from the condensation of propionoyl-CoA and oxaloacetic acid catalyzed by a citrate synthase enzyme. 2-Methylcitric acid is an endogenous tricarboxylic acid formed by the condensation of propionyl-CoA with oxaloacetic acid by citrate synthase under conditions of propionyl-CoA accumulation. Accumulation of 2-methylcitric acid is associated with cobalamin deficiencies, propionic acidemia, and methylmalonic acidurias. Group: Biochemicals. Alternative Names: 2-Hydroxy-1,2,3-butanetricarboxylic Acid. Grades: Highly Purified. CAS No. 6061-96-7. Pack Sizes: 50mg, 250mg. Molecular Formula: C?H??O?, Molecular Weight: 206.15. US Biological Life Sciences. | Worldwide |
4-beta-Hydroxy Cholesterol Quick inquiry Where to buy Suppliers range | 4-beta-Hydroxy Cholesterol is a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. It is also a potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Synonyms: (3β,4β)-Cholest-5-ene-3,4-diol; Cholest-5-ene-3β,4β-diol; 3β,4β-Dihydroxycholest-5-ene; cis-3,4-Dihydroxy-5-cholestene; cis-5-Cholestene-3,4-diol. Grades: > 95%. CAS No. 17320-10-4. Molecular formula: C27H46O2. Mole weight: 402.65. | |
4-Octyl itaconate Quick inquiry Where to buy Suppliers range | 4-Octyl itaconate is a prodrug form of itaconate, an endogenous cellular metabolite produced via decarboxylation of cis-aconitate by the enzyme encoded by IRG1. It activates Nrf2. It inhibits LPS-induced increases in IL-1β mRNA, HIF-1α and IL-10 in macrophages. It decreases cytokine production in response to LPS in mice and prolongs survival. Synonyms: Itaconic acid 4-octyl ester; 2-Methylidene-4-octoxy-4-oxobutanoic acid. Grades: ≥98%. CAS No. 3133-16-2. Molecular formula: C13H22O4. Mole weight: 242.3. | |
(±)5(6)-EET Ethanolamide Quick inquiry Where to buy Suppliers range | Arachidonyl ethanolamide (AEA) is an endogenous lipid neurotransmitter with cannabinergic activity. It binds to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of AEA. Synonyms: (±)5,6-EpETrE Ethanolamide; N-(2-hydroxyethyl)-4-[(2S,3R)-3-[(2Z,5Z,8Z)-tetradeca-2,5,8-trienyl]oxiran-2-yl]butanamide. Grades: ≥95%. Molecular formula: C22H37NO3. Mole weight: 363.5. | |
5-L-Isoleucineangiotensin II Quick inquiry Where to buy Suppliers range | 5-L-Isoleucineangiotensin II is an endogenous potent vasoconstrictor peptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE) by binding to both the AT1 and the AT2 receptors. Uses: An endogenous potent vasoconstrictor peptide. Synonyms: 5-Isoleucine-angiotensin II; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; Angiotensin II human; Human angiotensin II; Hypertensin; H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; Angiotensin II, 5-L-isoleucine-; Alanine, N-[1-[N-[N-[N-[N-(N2-L-α-aspartyl-L-arginyl)-L-valyl]-L-tyrosyl]-L-isoleucyl]-L-histidyl]-L-prolyl]-3-phenyl-, L-; 5-L-Isoleucine-angiotensin II; L-Phenylalanine, N-[1-[N-[N-[N-[N-(N2-L-α-aspartyl-L-arginyl)-L-valyl]-L-tyrosyl]-L-isoleucyl]-L-histidyl]-L-prolyl]-; [Ile5]-Ang II; [Ile5]-Angiotensin II; Angiotensin 2; Angiotensin II; Angiotensin II (human); Angiotensin II (mouse); Angiotensin II [Ile5]; Asp1-Ile5-angiotensin II; Human angiotensin II; Ileu5-angiotensin II; Isoleucyl5-angiotensin II. Grades: 98%. CAS No. 4474-91-3. Molecular formula: C50H71N13O12. Mole weight: 1046.19. | |
Angiotensin I human acetate salt hydrate Quick inquiry Where to buy Suppliers range | Angiotensin 1 (Human), an endogenous peptide substrate for angiotensin converting enzyme (ACE), is precursor to the vasoconstrictor peptide angiotensin II. Synonyms: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH.CH3CO2H.H2O. CAS No. 70937-97-2. Molecular formula: C64H95N17O17. Mole weight: 1374.54. | |
Angiotensin I (human, mouse, rat) Quick inquiry Where to buy Suppliers range | Angiotensin 1 (Human), an endogenous peptide substrate for angiotensin converting enzyme (ACE), is precursor to the vasoconstrictor peptide angiotensin II. Synonyms: Angiotensin 1 Human; H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-L-leucine; Pepsitensin; Proangiotensin; 5-Ile-angiotensin I; 5-L-Isoleucine-angiotensin I. Grades: ≥95%. CAS No. 484-42-4. Molecular formula: C62H89N17O14. Mole weight: 1296.48. | |
Angiotensin II (1-4), human Quick inquiry Where to buy Suppliers range | Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney. Uses: Peptide Inhibitors. CAS No. 52580-29-7. Product ID: R1200. | |
Angiotensin II (1-4), human Quick inquiry Where to buy Suppliers range | Angiotensin II (1-4), human is an endogenous peptide produced from ATI by angiotensin-converting-enzyme (ACE). Synonyms: H-DRVY-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosine; (S)-3-amino-4-((S)-1-((S)-1-((S)-1-carboxy-2-(4-hydroxyphenyl)ethylamino)-3-methyl-1-oxobutan-2-ylamino)-5-guanidino-1-oxopentan-2-ylamino)-4-oxobutanoic acid; L-α-Aspartyl-N5-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosine. Grades: ≥95%. CAS No. 52580-29-7. Molecular formula: C24H37N7O8. Mole weight: 551.59. | |
β-cyano-L-alanine Quick inquiry Where to buy Suppliers range | β-cyano-L-alanine is a reversible inhibitor of the H2S-synthesizing enzyme CSE. It blocks H2S synthesis in rat liver preparations with an IC50 value of 6.5 μM and increases blood pressure in anaesthetized rats induced with hemorrhagic shock by inhibiting endogenous H2S synthesis. Synonyms: BCA; beta-cyano-L-alanine; 3-Cyano-L-alanine; L-3-Cyanoalanine. Grades: ≥ 98% (TLC). CAS No. 6232-19-5. Molecular formula: C4H6N2O2. Mole weight: 114.1. | |
Danshensu Quick inquiry Where to buy Suppliers range | Danshensu is an active component of Salvia miltiorrhiza that shows wide cardiovascular benefit. It suppresses the formation of reactive oxygen species and inhibits platelet adhesion and aggregation. It also protects myocardium from the reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation. It increases production of collagenin Detroit 551 cells and attenuates the α-MSH-stimulated melanin production of B16 cells. It may be used as active ingredients in would healing, cosmetic treatments or treating hyperpigmentation. It significantly decreased the level of the marker enzymes (creatine kinase and lactate dehydrogenase) from the coronary effluents and myocardial infarction size in vitro. It also had ROS scavenging activity and boosted endogenous antioxidants such as SOD, CAT, MDA, GSH-PX and HO-1 activities by activating nuclear factor erythroid-2-related factor 2 (Nrf2) signaling pathway which was mediated by Akt and ERK1/2 in western blot analysis. It significantly lowered tHcy in rats with elevated tHcy. Danshensu is a natural compound, which can also be used in cosmetics material. Synonyms: Benzenepropanoic acid, α,3,4-trihydroxy-, (αR)-; (αR)-α,3,4-Trihydroxybenzenepropanoic acid; Benzenepropanoic acid, α,3,4-trihydroxy-, (R)-; (R)-(+)-3-(3,4-Dihydroxyphenyl)lactic acid; (R)-3-(3,4-Dihydroxyphenyl)-2-hydroxypropionic acid; 3-(3',4'-Dihydroxyphenyl)-(2R)-lactic acid; D-(+)-β-(3,4-Dihydroxyphenyl)lactic acid; Dan Shen Su; Dan shen suan A; DS 182; Salianic acid A; Salvianic acid A; Tanshinol. Grades: >98%. CAS No. 76822-21-4. Molecular formula: C9H10O5. Mole weight: 198.17. | |
Dynorphin (1-17) Quick inquiry Where to buy Suppliers range | Dynorphin A-( 1- 17) is an endogenous opioid derived from the prohormone prodynorphin. It acts as endogenous κ-agonist that is resistant to enzymatic degradation. And it is a neuroactive peptide with potent analgesic effects. Uses: API. CAS No. 80448-90-4. Product ID: 10-101-81. | |
Dynorphin (1-17) Quick inquiry Where to buy Suppliers range | Dynorphin A is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Uses: Neurotransmitter agents. Synonyms: Dynorphin A (swine); Dynorphin A (pig); 1-17-Dynorphin; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-; Dyn-A17; Dynorphin 17; Dynorphin A; Dynorphin A (1-17); Dynorphin A (human); Dynorphin A (porcine); Dynorphin A (rat); Dynorphin A 1-17; Dynorphin-A (Bos taurus); Porcine dynorphin (1-17); Porcine dynorphin A (1-17); Proteins, Dyn-A17; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln. Grades: ≥95%. CAS No. 80448-90-4. Molecular formula: C99H155N31O23. Mole weight: 2147.51. | |
Dynorphin A acetate Quick inquiry Where to buy Suppliers range | Dynorphin A acetate is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Synonyms: Dynorphin (1-17) acetate; Dynorphin A (human, pig, rat, Bos taurus) acetate; Porcine dynorphin (1-17) acetate; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-, acetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C101H159N31O25. Mole weight: 2207.58. | |
Hemorphin-7 Quick inquiry Where to buy Suppliers range | Hemorphin-7 is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides exhibits antinociceptive and antihypertensive activities, activating opioid receptors and inhibiting angiotensin-converting enzyme (ACE). Uses: Peptide Inhibitors. CAS No. 152685-85-3. Product ID: R1414. | |
Hemorphin-7 Quick inquiry Where to buy Suppliers range | Hemorphin-7, a hemorphin peptide with antinociceptive and antihypertensive effects, is an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides activates opioid receptors and inhibiting angiotensin-converting enzyme (ACE). The much lower affinity of hemorphin- 7 for μ-receptors as compared to other opioid peptides may be compensated by its much higher plasma concentration, resulting in biological effects of comparable magnitude. Synonyms: H-Tyr-Pro-Trp-Thr-Gln-Arg-Phe-OH; L-tyrosyl-L-prolyl-L-tryptophyl-L-threonyl-L-glutaminyl-L-arginyl-L-phenylalanine; L-Phenylalanine, N-(N2-(N2-(N-(N-(1-L-tyrosyl-L-prolyl)-L-tryptophyl)-L-threonyl)-L-glutaminyl)-L-arginyl)-. Grades: ≥97%. CAS No. 152685-85-3. Molecular formula: C49H64N12O11. Mole weight: 997.11. | |
JZL195 Quick inquiry Where to buy Suppliers range | JZL195 is a potent dual inhibitor of Monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH), enzymes that degrade the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA), the endogenous ligands for the cannabinoid G-protein coupled receptors CB1 and CB2. IC50 values are 2 nM for MAGL and 4 nM for FAAH. JZL195 has been shown to inhibit endocannabinoid hydrolysis and elevate 2-AG and AEA levels in vivo. Synonyms: JZL195; JZL-195; JZL 195. Grades: >98%. CAS No. 1210004-12-8. Molecular formula: C24H23N3O5. Mole weight: 433.46. | |
LHW090-A7 sodium Quick inquiry Where to buy Suppliers range | LHW090-A7 is an inhibitor of neutral endopeptidase (NEP), an enzyme responsible for the metabolic inactivation of enkephalins. It has been shown to induce the increase of plasma levels of endogenous atrial natriuretic peptides (NPs). Synonyms: (S)-3-(3'-Chloro-[1,1'-biphenyl]-4-yl)-2-(((S)-1-ethoxy-1-oxopropan-2-yl)amino)propanoic sodium salt. Grades: ≥98%. Molecular formula: C20H21ClNO4·Na. Mole weight: 397.8. | |
Liarozole hydrochloride Quick inquiry Where to buy Suppliers range | Liarozole is a benzimidazole derivative with potential antineoplastic activity. As a retinoic acid metabolism blocking agent (RAMBA), liarozole inhibits cytochrome P450-dependent all-trans-retinoic acid (ATRA)-4-hydroxylase, resulting in an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. This agent also inhibits aromatase, the enzyme that catalyzes the final, rate-limiting step in estrogen biosynthesis. Synonyms: Liarozole HCl; R75251 (hydrochloride); 5-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole hydrochloride. CAS No. 145858-50-0. Molecular formula: C17H14Cl2N4. Mole weight: 345.23. | |
Nafazatrom Quick inquiry Where to buy Suppliers range | Nafazatrom is a pyrazolinone derivative. It increases endogenous prostacyclin (PGI2) and has potential antimetastatic activities. It is used an antithrombotic drug that increases PGI2 levels. It inhibits the key prostaglandin catabolic enzyme, 15-hydroxyprostaglandin dehydrogenase, which prolongs the biological half-life of PGI2 and prevents intravascular coagulation. It also serves as a reducing cofactor with the hydroperoxidase moiety of cyclooxygenase and accelerates the conversion of arachidonic acid into precursors of PGI2. It is a lipoxygenase inhibitor, reduces stimulated Prolactin secretion. It also reduces the incidence of accompanying arrhythmias in myocardial injuries. Uses: Nafazatrom is used an antithrombotic drug. Synonyms: 2,4-Dihydro-5-methyl-2-[2-(2-naphthalenyloxy)ethyl]-3H-pyrazol-3-one; Bay-g-6575; BAY g 6575; 3-methyl-1-(2-(naphthalen-2-yloxy)ethyl)-1H-pyrazol-5(4H)-one. Grades: 98%. CAS No. 59040-30-1. Molecular formula: C16H16N2O2. Mole weight: 268.32. | |
SB 706375 Quick inquiry Where to buy Suppliers range | SB 706375 is a high affinity and non-peptide antagonist of the mammalian urotensin-II (UT) receptor displaying ≥100-fold selectivity for the human UT receptor over 86 different receptors, ion channels, enzymes, transporters and nuclear hormones. SB 706375 also inhibits binding of radiolabeled urotensin to endogenous human UT receptors (Ki = 5.4 nM in a whole-cell binding assay). Synonyms: SB-706375; SB 706375; SB706375. 2-Bromo-4, 5-dimethoxy-N-[3-[[ (3R) -1-methyl-3-pyrrolidinyl]oxy]-4- (trifluoromethyl) phenyl]benzenesulfonamide. Grades: ≥98% by HPLC. CAS No. 733734-61-7. Molecular formula: C20H22BrF3N2O5S. Mole weight: 539.36. | |
Semagacestat Quick inquiry Where to buy Suppliers range | Semagacestat is an inhibitor of the γ-secretase enzyme. γ-Secretase enzyme is pivotal in the generation of β-amyloid (A β), a neurotoxic endogenous peptide believed to be involved in the pathogenesis of Alzheimer's disease (AD). Group: Biochemicals. Alternative Names: (2S) -2-Hydroxy-3-methyl-N- [ (1S) -1-methyl-2-oxo-2- [ [ (1S) -2, 3, 4, 5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl] amino] ethyl] butanamide; LY 450139. Grades: Highly Purified. CAS No. 425386-60-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
SJB2-043 Quick inquiry Where to buy Suppliers range | SJB2-043 is one of analogs/derivatives of C527, which is a novel and potent USP1 (ubiquitin-specific protease 1) inhibitor. It inhibited the Ub-VS labeling of a limited number of endogenous DUB enzymes and inhibited the labeling of USP1 with Ub-VS in a dose dependent manner. Synonyms: SJB2-043; SJB2043; SJB2 043. Grades: >98%. CAS No. 63388-44-3. Molecular formula: C17H9NO3. Mole weight: 275.26. | |
Spinorphin Quick inquiry Where to buy Suppliers range | Spinorphin is an endogenous opioid heptapeptide that exhibits inhibitory effects on enkephalin-degrading enzymes. The mechanism of action of spinophin has not been fully elucidated but it has been found to act as an antagonist of the P2X3 receptor, and as a weak partial agonist/antagonist of the FP1 receptor. Uses: Peptide Inhibitors. CAS No. 137201-62-8. Product ID: R1871. | |
Spinorphin Quick inquiry Where to buy Suppliers range | Spinorphin is an endogenous neuropeptide that inhibits enkephalin-degrading enzymes (aminopeptidase, dipeptidyl aminopeptidase III, neprilysin) and angiotensin-converting enzyme. Spinorphin exhibits antinociceptive effects in mice. Synonyms: L-Threonine, N-(N-(1-(N-(N-(N-L-leucyl-L-valyl)-L-valyl)-L-tyrosyl)-L-prolyl)-L-tryptophyl)-. CAS No. 137201-62-8. Molecular formula: C45H64N8O10. Mole weight: 877.03. | |
UDP-D-glucuronide trisodium salt Quick inquiry Where to buy Suppliers range | UDP-D-glucuronide trisodium salt is a crucial compound used for drug metabolism studies. It acts as a donor molecule for the glucuronyl transferase enzyme, which helps in the biotransformation and detoxification of a wide range of drugs and endogenous compounds. This trisodium salt form facilitates stability and solubility, making it suitable for drug discovery and pharmacokinetic studies. Synonyms: UDP-GlcA; Uridine 5-diphosphoglucuronic acid trisodium salt; UDPGA; Uridine-diphosphate-glucuronic acid trisodium salt. Grades: 98%. CAS No. 63700-19-6. Molecular formula: C15H19N2Na3O18P2. Mole weight: 646.24. | |
Zinc protoporphyrin IX Quick inquiry Where to buy Suppliers range | Zinc protoporphyrin IX is an endogenous metabolite formed during heme biosynthesis and a heme oxygenase inhibitor. Heme oxygenase is the enzyme producing CO, which is an activator of guanylyl cyclase and shares some chemical and biological properties of NO. Zinc protoporphyrin IX has been shown to inactivates the NOS isoforms nNOS, iNOS, and eNOS(IC50 = 0.8, 4, and 5 μM, respectively). Synonyms: 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid, zinc complex; Zinc protoporphyrin-9; ZnPP; Zinc 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,23-diid-2-yl]propanoic acid; Zn-Protoporphyrin IX. CAS No. 15442-64-5. Molecular formula: C34H32N4O4Zn. Mole weight: 626.03. |