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(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: Ethyl (2R,4S)-4-amino-5-(4-biphenylyl)-2-methylpentanoate hydrochloride; (αR,γS)-γ-Amino-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid Ethyl Ester Hydrochloride; (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride. CAS No. 149690-12-0. Molecular formula: C20H26ClNO2. Mole weight: 347.88.
Ethyl Isobutyrylacetate is used in the synthesis of piperazine derivatives as possible multireceptor atypical antipsychotics, affecting dopamine and serotonin receptor properties. Also used in the synthesis of pyrazinecarboxamide DGAT1 (diacylglycerol acyltransferase 1) inhibitors used in the treatment of obesity. Group: Biochemicals. Alternative Names: 3-Oxo-4-methylpentanoic Acid Ethyl Ester; 4-Methyl-3-oxo-pentanoic Acid Ethyl Ester; 4-Methyl-3-oxovaleric Acid Ethyl Ester; Ethyl 2-isobutyrylacetate; Ethyl 3-Isopropyl-3-oxopropanoate; Ethyl 3-oxo-4-methylpentanoate; Ethyl 3-Oxo-4-methylvalerate; Ethyl 4-Methyl-3-oxopentanoate; Ethyl 4-Methyl-3-oxovalerate; Ethyl Isobutyrylacetate; Isobutyrylacetic Acid Ethyl Ester; NSC 62029; γ,γ-Dimethylacetoacetic Acid Ethyl Ester; Ethyl 4-Methyl-3-oxopentanoate. Grades: Highly Purified. CAS No. 7152-15-0. Pack Sizes: 5g. US Biological Life Sciences.
Sacubitril-(2S, 4S)-isomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Synonyms: (2S,4S)-Sacubitril; 149709-63-7; 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; 4-[[(2S,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; [1,1'-Biphenyl]-4-pentanoic acid, gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl-, alpha-ethyl ester, (alphaS,gammaS)-; LCZ 696 Impurity C; SCHEMBL18059568; DTXSID901127620; AKOS030528363; AS-80403; HY-78841; CS-0009335; 3-{[(2S,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid; 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoicacid; alpha-Ethyl (alphaS,gammaS)-gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl[1,1'-biphenyl]-4-pentanoate. Grades: > 95%. CAS No. 149709-63-7. Molecular formula: C24H29NO5. Mole weight: 411.5.
Sacubitril N-Boc Ester
Sacubitril N-Boc Ester is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: Ethyl (2R, 4S) -5- (4-biphenylyl) -2-methyl-4- ({[ (2-methyl-2-propanyl) oxy]carbonyl}amino) pentanoate; (αR,γS)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-Biphenyl]-4-pentanoic Acid Ethyl Ester; [1,1'-Biphenyl]-4-pentanoic acid, gamma-[[(1,1-dimethylethoxy)carbonyl]amino]-alpha-methyl-, ethyl ester, (alphaR,gammaS)-; Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-4-[(tert-butoxycarbonyl)amino]-2-methylbutanoate. CAS No. 149709-60-4. Molecular formula: C25H33NO4. Mole weight: 411.53.
2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-d5-ethyl]-4-methyl-3-oxo-pentanoic acid,(2-benzyloxy-phenyl)-amide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-D5-ethyl]-4-methyl-3-oxo-pentanoic Acid, (2-Benzyloxy-phenyl)-amide. Product Category: Heterocyclic Organic Compound. Appearance: Light Yellow Foamy Solid. CAS No. 1020719-43-0. Molecular formula: C33H25D5FNO4. Mole weight: 528.6248121. Product ID: ACM1020719430. Alfa Chemistry ISO 9001:2015 Certified.
Vitamin D3 analog. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),[1] is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.[2] At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days.[3] Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation.[4][5]. Group: Biochemicals. Alternative Names: ( ε R, 1R, 3aS, 4E, 7aR) -4- [ (2Z) -2- [ (5S) -5- (3-Aminopropoxy) -2- methyl enecyclohexylidene] ethylidene] octahydro- α , α , ε , 7a-tetra methyl -1H-indene-1-pentanol; (3 β,5Z,7E)-3-(3-Aminopropoxy)-9,10-secocholesta-5,7,10(19)-trien-25-ol; 3-O-(2-Aminoethyl)-25-hydroxyvitamin D3. Grades: Highly Purified. CAS No. 163018-26-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
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2-Methyl-1,3-dioxolane-2-propanoic Acid
2-Methyl-1,3-dioxolane-2-propanoic Acid. Group: Biochemicals. Alternative Names: 3-(2-Methyl-1,3-dioxolan-2-yl)propanoic Acid; Levulinic Acid Cyclic Ethylene Acetal; 4-Oxo-pentanoic Acid Cyclic 1,2-Ethanediyl Acetal. Grades: Highly Purified. CAS No. 4388-57-2. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
2-Methyl-1,3-dioxolane-2-propanol-d4
An intermediate in the preparation of labeled Cletoquine, Chloroquine and respective derivatives. Group: Biochemicals. Alternative Names: 4,4-(Ethylenedioxy)-1-pentanol. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
2-Pentanone
2-Pentanone. Group: Biochemicals. Alternative Names: 4-Methyl-2-butanone; Ethylacetone; Methyl n-Propyl Ketone; Methyl Propyl Ketone; NSC 5350; Propyl Methyl Ketone. Grades: Highly Purified. CAS No. 107-87-9. Pack Sizes: 100g. Molecular Formula: C5H10O, Molecular Weight: 86.13. US Biological Life Sciences.
Worldwide
(2R,4R)-Sacubitril
(2R,4R)-Sacubitril. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (?R,?R)-rel-?-[(3-Carboxy-1-oxopropyl)amino]-?-methyl-[1,1'-biphenyl]-4-pentanoic Acid 4-Ethyl Ester, Sacubitril-(2R,4R) Isomer,Impurity B,(R*,R*)-?-[(3-Carboxy-1-oxopropyl)amino]-?-methyl-[1,1'-biphenyl]-4-pentanoic Acid ?-Ethyl Ester. CAS No. 766480-48-2. IUPAC Name: (4Z)-4-[4-ethoxy-3-methyl-4-oxo-1-[(4-phenylphenyl)methyl]butyl]imino-4-hydroxy-butanoic acid. Molecular formula: C24H29NO5. Mole weight: 411.49. Catalog: APS766480482. SMILES: CCOC(=O)C(C)CC(Cc1ccc(cc1)c2ccccc2)\N=C(/O)\CCC(=O)O. Format: Neat.
3- [ [ [ (1S) -1- (Aminocarbonyl) -2-methylpropyl] amino] carbonyl] -1H-Indazole-1-pentanoic Acid Ethyl Ester is an intermediate in the synthesis of AB Pinaca 5-Pentanoic Acid (A109010). AB Pinaca 5-Pentanoic Acid is a metabolite of the synthetic cannabinoid AB-Pinaca (A109000). Group: Biochemicals. Grades: Highly Purified. CAS No. 1887742-38-2. Pack Sizes: 10mg, 25mg. Molecular Formula: C20H28N4O4, Molecular Weight: 388.46. US Biological Life Sciences.
The epimer metabolite of Calcifediol or 25-hydroxyvitamin D3. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),[1] is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.[2] At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days.[3] Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation.[4][5]. Group: Biochemicals. Alternative Names: ( ε R, 1R, 3aS, 4E, 7aR) -Octahydro-4- [ (2Z) -2- [ (5R) -5-hydroxy-2- methyl enecyclohexylidene] ethylidene] - α , α , ε , 7a-tetra methyl -H-indene-1-pentanol; (3α,5Z,7E)-9,10-Seco-cholesta-5,7,10(19)-triene-3,25-diol; 3-epi-25-Hydroxyvitamin D3. Grades: Highly Purified. CAS No. 73809-05-9. Pack Sizes: 250ug. US Biological Life Sciences.
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3-Ethyl-3-methyl-2-pentanone
3-Ethyl-3-methyl-2-pentanone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-ETHYL-3-METHYL-2-PENTANONE;2-Pentanone, 3-ethyl-3-methyl-. Product Category: Heterocyclic Organic Compound. CAS No. 19780-65-5. Molecular formula: C8H16O. Mole weight: 128.21. Product ID: ACM19780655. Alfa Chemistry ISO 9001:2015 Certified.
3-Methyl-1-pentanal
3-Methyl-1-pentanal. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-METHYLVALERALDEHYDE;3-METHYL-1-PENTANAL;3-Ethylbutanal;3-Methylpentanal;C2H5CH(CH3)CH2CHO;pentanal,3-methyl;Pentanal,3-methyl-;Valeraldehyde, 3-methyl-. Product Category: Heterocyclic Organic Compound. CAS No. 15877-57-3. Molecular formula: C6H12O. Mole weight: 100.16. Purity: 0.96. IUPACName: 3-methylpentanal. Canonical SMILES: CCC(C)CC=O. Density: 0.799g/cm³. ECNumber: 240-014-6. Product ID: ACM15877573. Alfa Chemistry ISO 9001:2015 Certified. Categories: 3-Methyl-1-pentanol.
3-Methyl-3-hexanol
3-Methyl-3-hexanol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ETHYLMETHYLPROPYLCARBINOL;3-METHYL-3-HEXANOL;(±)-3-methyl-hexan-3-ol;2-Ethyl-2-pentanol;3-methyl-3-hexano;3-Methyl-hexanol-(3);Ethyl methyl n-propyl carbinol;3-Methyl-3-hexanol,99%. Product Category: Heterocyclic Organic Compound. CAS No. 597-96-6. Molecular formula: C7H16O. Mole weight: 116.2. Purity: 0.96. IUPACName: 3-methylhexan-3-ol. Canonical SMILES: CCCC(C)(CC)O. Density: 0,823. ECNumber: 209-910-4. Product ID: ACM597966. Alfa Chemistry ISO 9001:2015 Certified.
3-O-Benzyl-(1R)-hydroxy Tapentado-d5
Intermediate in the preparation of labeled Tapentadol. Group: Biochemicals. Alternative Names: (α R) -α -[ (1S) -2- (Dimethylamino) -1-methylethyl]-α -ethyl-3- (phenylmethoxy) benzenemethanol-d5; (2S,3R)-1-(Dimethylamino)-3-[3-(benzyloxy)phenyl)-2-methyl-3-pentanol-d5. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
4-methyl-3-hexanol
4-methyl-3-hexanol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-methylhexan-3-ol;2-Ethyl-3-pentanol, 4-Methylhexan-3-ol, 3-Hexanol, 4-methyl-, 3-Methyl-4-hexanol, 4-METHYL-3-HEXANOL, NSC91500, MolPort-003-910-334, CID11991, EINECS 210-419-2, 615-29-2. Product Category: Insect Pheromone. CAS No. 615-29-2. Molecular formula: C7H16O. Mole weight: 116.204. Purity: 0.96. IUPACName: 4-methylhexan-3-ol. Canonical SMILES: CCC(C)C(CC)O. Density: 0.816g/cm³. ECNumber: 210-419-2. Product ID: ACM615292. Alfa Chemistry ISO 9001:2015 Certified.
5-Chloro-2-pentanone ethylene ketal
5-Chloro-2-pentanone ethylene ketal. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ambaga3160, 151556_ALDRICH, 2,2-(Ethylenedioxy)-5-chloropentane, MolPort-001-792-036, NSC135783, CID80079, EINECS 227-776-5, 5-Chloro-2-pentanone ethylene ketal, ZINC01722123, 1,3-Dioxolane, 2-(3-chloropropyl)-2-methyl-, 2-(3-Chloropropyl)-2-methyl-1,3-dioxolane, LS-62526, 5978-08-5, 6681-11-4. Product Category: Heterocyclic Organic Compound. CAS No. 5978-8-5. Molecular formula: C7H13ClO2. Mole weight: 164.629920 [g/mol]. Purity: 0.96. IUPACName: 2-(3-chloropropyl)-2-methyl-1,3-dioxolane. Canonical SMILES: CC1(OCCO1)CCCCl. Density: 1.094 g/mL at 25ºC(lit.). ECNumber: 227-776-5. Product ID: ACM5978085. Alfa Chemistry ISO 9001:2015 Certified.
It is used as a substrate in a rapid, sensitive, continuous spectrophotometric assay for vertebrate collagenase, gelatinase A, and gelatinase B. Synonyms: Glycine, 1-acetyl-L-prolyl-L-leucylglycyl-2-mercapto-4-methylpentanoyl-L-leucyl-, ethyl ester. CAS No. 98992-65-5. Molecular formula: C31H53N5O8S. Mole weight: 655.85.
Beta phenyl ethyl methyl ethyl carbinyl acetate
Beta phenyl ethyl methyl ethyl carbinyl acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PHENYL ETHYL METHYL ETHYL CARBINYL ACETATE;BETA PHENYL ETHYL METHYL ETHYL CARBINYL ACETATE;1-ethyl-1-methyl-3-phenylpropylacetate;1-phenyl-3-methyl-3-pentanylacetate;3-methyl-1-phenyl-3-pentanoacetate;alpha-ethyl-alpha-methyl-benzenepropanoacetate;Benzen. Product Category: Heterocyclic Organic Compound. CAS No. 72007-81-9. Molecular formula: C14H20O2. Mole weight: 220.31. Product ID: ACM72007819. Alfa Chemistry ISO 9001:2015 Certified.
Boc-N-ethyl-L-leucine dicyclohexylammonium salt
Boc-N-ethyl-L-leucine dicyclohexylammonium salt. Group: Biochemicals. Alternative Names: Boc-N-Et-L-Leu-OH·DCHA; (S)-Boc-N-Ethyl-2-amino-4-methyl-pentanoic acid dicyclohexylammonium salt. Grades: Highly Purified. CAS No. 200936-83-0. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Calcifediol
Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM). Uses: Treatment of osteoporosis. Synonyms: (3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol; 25-Hydroxycholecalciferol; 25-Hydroxyvitamin D; 25-Hydroxyvitamin D3; Calcidiol; Didrogyl; Hidroferol; Ro 8-8892; U 32070E; 25-OH Vitamin D3; Rayaldee; 5,6-cis-25-Hydroxyvitamin D3; (3S,5Z,7E,20R)-9,10-Secocholesta-5,7,10-triene-3,25-diol; 1H-Indene-1-pentanol, octahydro-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]-α,α,ε,7a-tetramethyl-, (εR,1R,3aS,4E,7aR)-. Grades: >98%. CAS No. 19356-17-3. Molecular formula: C27H44O2. Mole weight: 400.64.
D-Leucine ethyl ester hydrochloride
D-Leucine ethyl ester hydrochloride. Group: Biochemicals. Alternative Names: D-Leu-OEt·HCl; (R)-2-amino-4-methyl-pentanoic acid ethyl ester hydrochloride. Grades: Highly Purified. CAS No. 73913-65-2. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
Homopravastatin derivative, an impurity of Pravastatin. Group: Biochemicals. Alternative Names: 2-Methyl-pentanoic Acid [1S-[1α(R*),3 β,7 β,8 β(2S*,4S*),8a β ] ] -3- [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] -8- [2- [4- [ [ (1, 1-dimethylethyl) dimethylsilyl] oxy] tetrahydro-6-oxo-2H-pyran-2-yl] ethyl] -1, 2, 3, 7, 8, 8a-hexahydro-7-methyl-1-naphthalenyl Ester. Grades: Highly Purified. CAS No. 159224-68-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
methanol O-anthraniloyltransferase
The enzyme from Concord grape (Vitis labrusca) is solely responsible for the production of O-methyl anthranilate, an important aroma and flavor compound in the grape. The enzyme has a broad substrate specificity, and can use a range of alcohols with substantial activity, the best being butanol, benzyl alcohol, iso-pentanol, octanol and 2-propanol. It can use benzoyl-CoA and acetyl-CoA as acyl donors with lower efficiency. In addition to O-methyl anthranilate, the enzyme might be responsible for the production of ethyl butanoate, methyl-3-hydroxy butanoate and ethyl-3-hydroxy butanoate, which are present in large quantities in the grapes. Also catalyses EC 2.3.1.196, benzyl alcohol O-benzoyltransferase. Group: Enzymes. Synonyms: AMAT; anthraniloyl-coenzyme A (CoA):methanol acyltransferase. Enzyme Commission Number: EC 2.3.1.232. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2180; methanol O-anthraniloyltransferase; EC 2.3.1.232; AMAT; anthraniloyl-coenzyme A (CoA):methanol acyltransferase. Cat No: EXWM-2180.
Phoslactomycin D
It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Synonyms: Pentanoic acid, 4-methyl-, 3-(8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl)cyclohexyl ester. CAS No. 122856-28-4. Molecular formula: C31H50NO10P. Mole weight: 627.70.
Sacubitril Enantiomer
Sacubitril enantiomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Synonyms: 2R,4S-Sacubitril; (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester; 4-[[(2R,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; (2S,4R)-Sacubitril; SCHEMBL22420467; CS-M3545; AKOS030528367; HY-78847; MS-27102; PD100765; L10003; EN300-6474615; A854860; [1,1'-Biphenyl]-4-pentanoic acid, |A-[(3-carboxy-1-oxopropyl)amino]-|A-methyl-, 4-ethyl ester, (|AS,|AR)-; 3-{[(2R,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid; 4-(((2R,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; (alphaS,gammaR)-gamma-[(3-Carboxy-1-oxopropyl)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester. Grades: > 95%. CAS No. 761373-05-1. Molecular formula: C24H29NO5. Mole weight: 411.5.
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