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1, 3-bis ( (1r, 4R) -4- (2- (4- (2, 3-Dichlorophenyl) piperazin-1-yl) ethyl) cyclohexyl) urea, is an impurity of Cariprazine, an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C37H52Cl4N6O, Molecular Weight: 738.66. US Biological Life Sciences.
Etifoxine intermediate. Group: Biochemicals. Alternative Names: N-[4-Chloro-2-(1-hydroxy-1-phenylethyl)phenyl]-N'-ethyl-thiourea. Grades: Highly Purified. CAS No. 21740-97-6. Pack Sizes: 100mg. US Biological Life Sciences.
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1-(4-Chlorophenyl)sulfonyl-1-ethyl-3-propyl-urea
Heterocyclic Organic Compound. CAS No. 117048-15-4. Catalog: ACM117048154.
2,3,4,6-Tetra-O-acetyl-N-(b-D-galactopyranosyl)-N'-[(2-methanethiosulfonyl)ethyl]urea is a biomedical product used in the treatment of certain diseases. This compound acts as an inhibitor and is commonly employed in research for studying specific drug targets and mechanisms. It demonstrates potential applications in precision medicine and drug development due to its unique chemical structure and properties. Synonyms: Acetyl-MTS-5-galactose. Molecular formula: C17H26N2O12S2. Mole weight: 514.53.
2,3,4,6-Tetra-O-acetyl-N-(β-D-galactopyranosyl)-N'-[(2-methanethiosulfonyl)ethyl]urea, a compelling biomedicine for cancer treatment, showcases its academic and scientific prowess. As a potent selective inhibitor, it deftly targets crucial enzymes implicated in tumor growth. Through its distinctive chemical composition, it proficiently impedes the proliferation of cancer cells, inducing apoptosis effectively. Synonyms: Acetyl-MTS-5-Galactose. Grades: 98%. Molecular formula: C18H28N2O12S2. Mole weight: 528.55.
MTS-galactose derivatives are useful in probing catalytic mechanisms. Molecular formula: C22H52N2O8S2Si4. Mole weight: 649.13.
2-Imidazolidone (Ethylene urea)
500g Pack Size. Group: Building Blocks, Organics. Formula: C3H6N2O. CAS No. 120-93-4. Prepack ID 33967267-500g. Molecular Weight 86.09. See USA prepack pricing.
Ethylene Urea-d4. Group: Biochemicals. Alternative Names: 2-Imidazolidinone-4,4,5,5-d4. Grades: Highly Purified. CAS No. 62740-68-5. Pack Sizes: 10mg. US Biological Life Sciences.
N-(b-D-Glucopyranosyl)-N-[(2-methanethiosulfonyl)ethyl]urea is an N-alkylating compound with potential anti-cancer properties. Further research suggests its applicability in studying various tumor types. Synonyms: MTS-5-glucose. Molecular formula: C10H20N2O8S2. Mole weight: 360.40.
N-(b-D-Glucopyranosyl)-N'-[(2-methanethiosulfonyl)ethyl]urea is a highly intricate and multifaceted biomedical compound, showcasing its remarkable potential in studying a wide range of ailments. Functioning as a potent inhibitor, it targets the activities of distinctive enzymes or proteins intricately linked to these afflictions. Synonyms: MTS-5-glucose. Molecular formula: C10H20N2O8S2. Mole weight: 360.40.
N-(β-D-Glucopyranosyl)-N'-[(2-methanethiosulfonyl)ethyl] Urea, a biomedical product, has garnered attention in academia and the scientific world for its multifaceted potential in disease treatment. The exquisite design of this product enables it to act as an inhibitor that selectively targets and impedes the enzymatic activity crucial to the progression of varied illnesses. Considered a cornerstone in biomedical research, it holds promise in elucidating the intricate mechanisms governing diabetes, cancer, and neurological disorders, while also paving the way for novel therapeutic interventions. Synonyms: MTS-5-Glucose; Methanesulfonothioic Acid S-[2-[[ (β -D-Glucopyranosylamino) carbonyl]amino]ethyl] Ester. Grades: 98%. CAS No. 550325-52-5. Molecular formula: C10H20N2O8S2. Mole weight: 360.4.
N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea. Group: Biochemicals. Alternative Names: GDC-0349. Grades: Highly Purified. CAS No. 1207360-89-1. Pack Sizes: 5mg. Molecular Formula: C24H32N6O3, Molecular Weight: 452.55. US Biological Life Sciences.
Worldwide
N-Ethyl-N'-(5-nitro-2-thiazolyl)urea
N-Ethyl-N'-(5-nitro-2-thiazolyl)urea. Group: Biochemicals. Alternative Names: Ba 32476; Hepzide; Hepzide 30; Nithiazid; Nithiazide. Grades: Highly Purified. CAS No. 139-94-6. Pack Sizes: 1g. Molecular Formula: C6H8N4O3S, Molecular Weight: 216.22. US Biological Life Sciences.
Worldwide
N,N'-Bis[2-(2-hydroxyethoxy)ethyl]-urea
N,N'-Bis[2-(2-hydroxyethoxy)ethyl]-urea can be synthesized from 2-(2-Aminoethoxy)ethanol (A609095), a widely used reactant that has been used in the preparation of TD-4306 as long-acting β2-agonist for asthma and COPD therapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 72877-98-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H20N2O5, Molecular Weight: 236.27. US Biological Life Sciences.
Worldwide
PRMT Inhibitor VI (1- (Benzo[d][1, 2, 3]thiadiazol-6-yl) -3- (2-cyclohexenylethyl) urea, 1-(1,2,3-Benzothiadiazol-6-yl)-3-[2-(1-cyclohexen-1-yl)ethyl]urea, Protein Arginine Methyltransferase Inhibitor VI)
A benzothiadiazolyl-cyclohexenylethylurea compound that binds to protein arginine methyltransferase 3 at the dimer interface and selectively inhibits PRMT3 activity in an allosteric manner (IC50 = 1.6uM), while being non-competitive with respect to AdoMet (S-adenosyl-L-methionine; SAM) or peptide substrates (Ki = 2.9 and 4.2 mM, respectively). Exhibits little or no inhibitory activity against PRMT1/4/5/8 or protein lysine methyltransferases, EHMT1, SUV39H2, SETD7, and SETD8, even at concentrations above 100uM. Although cell-permeable, it is metabolically unstable and therefore not recommended for cell cultures or in vivo applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?OS, Primary Target: PRMT3. US Biological Life Sciences.
Worldwide
S-Ethylisothio urea, hydrobromide
S-Ethylisothio urea, hydrobromide. Group: Biochemicals. Alternative Names: 2-Ethyl-2-thiopseudourea hydrobromide; Carbamimidothioic acid ethyl ester, hydrobromide; 2-Ethyl-2-thio-pseudourea monohydrobromide. Grades: Highly Purified. CAS No. 1071-37-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C3H9BrN2S. US Biological Life Sciences.
Potent DOT1L methyltransferase inhibitor (KD = 0.06nm, IC50 = 0.3nm in a radioactive assay); blocks H3K79 methylation in A431 cells and MCF10A cells (IC50 values are 2.65 and 8.8nm respectively). Inactive at 12 histone methyltransferases and DNMT1. Selectively kills cells transformed with the MLL-AF9 fusion oncogene in an in vitro model of leukemia; lowers levels of MLL target genes HOXA9 and Meis1. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Urea,ethyltrimethyl-(9ci)
Heterocyclic Organic Compound. CAS No. 113502-25-3. Catalog: ACM113502253.
Commonly known as EDAC, EDC or EDCI, this carbodiimide HCl salt is used as a coupling reagent in the synthesis of amides and carboxylic esters. EDAC is highly soluble in water and in most organic solvents, it can be employed in liquid and solid-phase and synthesis. The major advantage of EDCI over other carbodiimides such as DCC and DIC is the ease of purification of the product from the water-soluble urea by-product by washing the crude mixture with water or mild acid and extracting in the organic phase. The main applications of EDAC are in peptide synthesis, Steglich esterification reactions in presence of catalytic DMAP, immunoconjugate synthesis, synthesis of sulfo-NHS esters and coupling of biomolecules onto solid supports. Group: Biochemicals. Alternative Names: EDC.HCl; EDAC. HCl; Water Soluble Carbodiimide; N-Ethyl-N'- (3-dimethylaminopropyl) carbodiimide HCl; 1-Ethyl-3- (3-dimethylaminopropyl) carbodiimide HCl. Grades: Highly Purified. CAS No. 25952-53-8. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C8H17N3·HCl, Molecular Weight: 191.7. US Biological Life Sciences.
[2- [ [ [ (Phenylmethyl) amino] carbonyl] amino] ethyl] -carbamic Acid 1,1-dimethylethyl Ester is an intermediate in the synthesis of N-(Diaminoethylene)-N'-( β-D-ribofuranosyl)-carbamimidic Acid (D416225). It is used in the preperation of unsymmetrical ureas. Group: Biochemicals. Grades: Highly Purified. CAS No. 874394-05-5. Pack Sizes: 250mg, 500mg. Molecular Formula: C15H23N3O3. US Biological Life Sciences.
Acetohydroxamic acid is a potent irreversible Helicobacter pylori urease inhibitor used in the synthesis of pyrogallol and catechol derivatives. Uses: Enzyme inhibitors. Synonyms: Acetamide, N-hydroxy-; Acetic acid, oxime; Acetohydroximic acid; Acetylhydroxamic acid; Acetylhydroxylamine; AHA; AHA (urease inhibitor); Ethyl hydroxamic acid; Hydroxylamine, N-acetyl-; Methylhydroxamic acid; N-Acetylhydroxylamine; NSC 176136; NSC 408425; NSC 5073. Grades: ≥95%. CAS No. 546-88-3. Molecular formula: C2H5NO2. Mole weight: 75.07.
Agomelatine Impurity 26
Agomelatine Impurity 26. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1,3-bis(2-(7-methoxynaphthalen-1-yl)ethyl)urea. CAS No. 185421-27-6. Molecular Formula: C27H28N2O3. Mole Weight: 428.21. Catalog: APB185421276.
allophanate hydrolase
Along with EC 3.5.2.15 (cyanuric acid amidohydrolase) and EC 3.5.1.84 (biuret amidohydrolase), this enzyme forms part of thecyanuric-acid metabolism pathway, which degrades s-triazide herbicides, such as atrazine [2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine], in bacteria. The yeast enzyme (but not that from green algae) also catalyses the reaction of EC 6.3.4.6, urea carboxylase, thus bringing about the hydrolysis of urea to CO2 and NH3 in the presence of ATP and bicarbonate. The enzyme from Pseudomonas sp. strain ADP has a narrow substrate specificity, being unable to use the structurally analogous compounds urea, hydroxyurea or methylcarbamate as substrate. Group: Enzymes. Synonyms: allophanate lyase; AtzF; TrzF. Enzyme Commission Number: EC 3.5.1.54. CAS No. 9076-72-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4443; allophanate hydrolase; EC 3.5.1.54; 9076-72-6; allophanate lyase; AtzF; TrzF. Cat No: EXWM-4443.
AST487
AST487 / NVP-AST487 is a RET kinase inhibitor/FLT3 inhibitor with an IC(50) of 0.88 mumol/L on RET kinase, inhibits RET autophosphorylation and activation of downstream effectors, and potently inhibiting the growth of human thyroid cancer cell lines with activating mutations of RET but not of lines without RET mutations. Group: Fluorinated apis. Alternative Names: NVP-AST487. CAS No. 630124-46-8. Molecular formula: C26H30F3N7O2. Mole weight: 529.56. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 1-[4-[ (4-ethylpiperazin-1-yl)methyl]-3- (trifluoromethyl)phenyl]-3-[4-[6- (methylamino)pyrimidin-4-yl]oxyphenyl]urea. Catalog: OFC630124468.
biuret amidohydrolase
Along with EC 3.5.2.15 (cyanuric acid amidohydrolase) and EC 3.5.1.54 (allophanate hydrolase), this enzyme forms part of thecyanuric-acid metabolism pathway, which degrades s-triazide herbicides, such as atrazine [2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine], in bacteria.Urea-1-carboxylate rather than urea (as was thought previously) is the 2-nitrogen intermediate in cyanuric-acid metabolism in bacteria. The product, urea-1-carboxylate,can spontaneously decarboxylate under acidic conditions to form urea but, under physiological conditions, it can be converted into CO2 and ammonia by the action of EC 3.5.1.54. Group: Enzymes. Enzyme Commission Number: EC 3.5.1.84. CAS No. 95567-88-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4475; biuret amidohydrolase; EC 3.5.1.84; 95567-88-7. Cat No: EXWM-4475.
BTS 44595
BTS 44595 is a metabolite of Prochloraz, an effective fungicide against cereal powdery mildew. Synonyms: 1-Propyl-1-[2-[2,4,6-tri-chlorophenoxy]ethyl]-urea; N-Propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]urea; Prochloraz Metabolite BTS 44595; Urea, N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-. Grades: ≥95%. CAS No. 139520-94-8. Molecular formula: C12H15Cl3N2O2. Mole weight: 325.62.
Carbuterol acetate hydrate is an impurity of Carbuterol. Carbuterol is a β-adrenergic agonist related to isoproterenol with selectivity for airway smooth muscle receptors used as a bronchodilator. Synonyms: [5-(2-tert-Butylamino-1-hydroxyethyl)-2-hydroxyphenyl]-urea acetate; 1-(2-Hydroxy-5-{1-hydroxy-2-[(2-methyl-2-propanyl)amino]ethyl}phenyl)urea acetate (1:1). CAS No. 1613439-57-8. Molecular formula: C13H21N3O3.C2H4O2. Mole weight: 327.38.
Cariprazine Impurity 3
Cariprazine Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1,3-bis((1r,4R)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)urea. Molecular Formula: C37H52Cl4N6O. Mole Weight: 736.30. Catalog: APB05040.
Cimetidine Amide Dihydrochloride
Cimetidine Amide Dihydrochloride. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Cimetidine Amide Dihydrochloride, SKF-92422-A2,Cimetidine Hydrochloride Imp. C (EP), Cimetidine Hydrochloride Imp. C (EP) as Dihydrochloride, Cimetidine Imp. C (EP), Ph Eur Cimetidine Impurity C, Cimetidine Imp. C (EP) as Dihydrochloride, 1- [ (Methylamino) [ [2- [ [ (5-methyl-1H-imidazol-4-yl) methyl] sulphanyl] ethyl] amino] methylene] urea Dihydrochloride. CAS No. 52568-80-6. IUPAC Name: [methylamino- [2- [ (5-methyl-1H-imidazol-4-yl) methylsulfanyl] ethylamino] methylidene] urea; dihydrochloride. Molecular Formula: C10H18N6OS.2ClH. Mole Weight: 343.28. Catalog: APS52568806. SMILES: Cl.Cl.CNC(=NC(=O)N)NCCSCc1nc[nH]c1C. Format: Neat.
Cimetidine Amide Dihydrochloride
Impurity C of Cimetidine. Group: Biochemicals. Alternative Names: [ (Methylamino) [ [2- [ [5-methyl-1H-imidazol-4-yl) methyl] thio] ethyl] amino] methylene] - urea Dihydrochloride. Grades: Highly Purified. CAS No. 52568-80-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cimetidine EP Impurity C
Cimetidine Amide Dihydrochloride is an impurity of Cimetidine. Synonyms: Cimetidine Amide Dihydrochloride; [ (Methylamino) [[2-[[5-methyl-1H-imidazol-4-yl) methyl]thio]ethyl]amino]methylene]- urea Dihydrochloride. Grades: > 95%. CAS No. 52568-80-6. Molecular formula: C10H20Cl2N6OS. Mole weight: 343.28.
Cimetidine EP Impurity C
Cimetidine EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1- ( ( (2- ( ( (5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)amino) (methylamino)methylene)urea. CAS No. 77076-18-7. Molecular Formula: C10H18N6OS. Mole Weight: 270.13. Catalog: APB77076187.
Cimetidine EP Impurity C (Dihydrochloride)
Cimetidine EP Impurity C (Dihydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1- ( ( (2- ( ( (5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)amino) (methylamino)methylene)urea dihydrochloride. Molecular Formula: C10H18N6OS·2HCl. Mole Weight: 343.05. Catalog: APB05070.
D 106669
D 106669 is a potent and selective PI3K inhibitor. Synonyms: D-106669; D 106669; D106669; N-ethyl-N'-[3-[(4-methylphenyl)amino]pyrido[2,3-b]pyrazin-6-yl]Urea; 3-ethyl-1-{3-[(4-methylphenyl)amino]pyrido[2,3-b]pyrazin-6-yl}urea. Grades: 98%. CAS No. 938444-93-0. Molecular formula: C17H18N6O. Mole weight: 322.36.
EMD534085
EMD534085 is a potent and selective mitotic kinesin-5 inhibitor with an IC50 of 8 nM. Synonyms: 1-(2-(Dimethylamino)ethyl)-3-(((2R,4aS,5R,10bS)-5-phenyl-9-(trifluoromethyl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano(3,2-C)quinolin-2-yl)methyl)urea; EMD-534085; EMD 534085; N-[2-(Dimethylamino)ethyl]-N'-[[(2R,4aS,5R,10bS)-3,4,4a,5,6,10b-hexahydro-5-phenyl-9-(trifluoromethyl)-2H-pyrano[3,2-c]quinolin-2-yl]methyl]urea. Grades: ≥95%. CAS No. 858668-07-2. Molecular formula: C25H31F3N4O2. Mole weight: 476.53.
Ethyl Isocyanate
Ethyl isocyanate is part of a group of isocyanates that react with primary and secondary amines to form urea derivatives and carbamates. Ethyl isocyanate (among other isocyanate compounds, such as toluene isocyanate) are also thought to be the most common cause of occupational asthma. Group: Biochemicals. Grades: Highly Purified. CAS No. 109-90-0. Pack Sizes: 1g, 10g. Molecular Formula: C3H5NO, Molecular Weight: 71.08. US Biological Life Sciences.
Worldwide
Fobrepodacin
Fobrepodacin is an orally active and potent phosphate prodrug of SPR719 and has potent bactericidal activities in vivo. Synonyms: 2-(5-{2-[(ethylcarbamoyl)amino]-6-fluoro-7-[(2R)-oxolan-2-yl]-1H-benzimidazol-5-yl}pyrimidin-2-yl)propan-2-yl dihydrogen phosphate; N-Ethyl-N'-(6-fluoro-5-(2-(1-methyl-1-(phosphonooxy)ethyl)-5-pyrimidinyl)-7-((2R)-tetrahydro-2-furanyl)-1H-benzimidazol-2-yl)urea; SPR720; SPR-720; SPR 720; pVXc-486; pVXc 486; pVXc486; (R)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate. Grades: ≥98%. CAS No. 1384984-31-9. Molecular formula: C21H26FN6O6P. Mole weight: 508.44.
Gastrin/CCK antagonist 1
An antagonist of gastrin/CCK. Synonyms: Urea, N-[1-cyclohexyl-2,3,4,5-tetrahydro-2,4-dioxo-5-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1H-1,5-benzodiazepin-3-yl]-N'-(4-fluorophenyl)-. CAS No. 162271-52-5. Molecular formula: C28H32FN5O4. Mole weight: 521.58.
GBR-12935
GBR 12935 is a piperazine derivative and a potent and selective inhibitor of dopamine uptake with IC50 value of 3.7nM. It is found to have multiple binding sites in rat and human brains. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. It(1-9 nM) dose-dependently inhibited active uptake of [3H]dopamine in homogenates of the nucleus accumbens and could inhibit DA uptake with IC50 value of 3.7nM in vitro. It elevated locomotion to a greater extent in C57BL/6J mice at the maximally active dose of 10 mg/kg in vivo. It shows a Kd value of 1.08nM in dopamine transporter transfected COS-7 cells. It is now widely used in animal research into Parkinson's disease and the dopamine pathways in the brain. Uses: Gbr 12935 inhibits da uptake with ic50 value of 3.7nm in vitro. it elevated locomotion to a greater extent in c57bl/6j mice at the maximally active dose of 10 mg/kg in vivo. it shows a kd value of 1.08nm in dopamine transporter transfected cos-7 cells. Synonyms: GBR-12935; GBR 12935; GBR12935; 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine; 1-Hydrocinnamyl-4-[2-(diphenylmethoxy)ethyl]piperazine; Piperazine, 1-(2-(diphenylmethoxy)ethyl)-4-(3-phenylpropyl)-;N-[3-tert-Butyl-1-(4-Methylphenyl)-1H-pyrazol-5-yl]-N-[4-[2-(4-Morpholinyl)ethoxy]naphthalen-1-yl]urea;1-(2-(Benzhydryloxy)ethyl)-4-(3-phenylpropyl)piperazine. Grades: 98%. CAS No. 76778-22-8. Molecular formula: C28H34N2O. Mole weight: 414.58.
Gliamilide
Gliamilide is a high-potency Sulfonated urea hypoglycemic agent. Uses: Gliamilide is used as a hypoglycemic agent. Synonyms: CP-27,634; CP 27,634; CP27,634; endo-1- ( (4- (2- (2-Methoxynicotinamido) ethyl) piperidino) sulfonyl) -3- (5-norbornen-2-ylmethyl) urea. Grades: 98%. CAS No. 51876-98-3. Molecular formula: C23H33N5O5S. Mole weight: 491.61.
Glimepiride Impurity A
Glimepiride Impurity A is the cis-isomer of Glimepiride found in a bulk drug substance. Glimepiride is an antidiabetic medication used to treat type 2 diabetes. Synonyms: 1-[[p-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(cis-4-methylcyclohexyl)urea; 3-Ethyl-2, 5-dihydro-4-methyl-N- [2- [4- [ [ [ [ (cis-4-methylcyclohexyl) amino] carbonyl] amino] sulfonyl] phenyl] ethyl] -2-oxo-1H-pyrrole-1-carboxamide; Gl. Grades: > 95%. CAS No. 684286-46-2. Molecular formula: C24H34N4O5S. Mole weight: 490.63.
Glipizide EP Impurity H is an impurity of Glipizide. Synonyms: 1-Cyclohexyl-3-(p-sulfaMoylphenethyl)urea; 4- [2- [ [ (CyclohexylaMino) carbonyl] aMino] ethyl] benzenesulfonaMide. Grades: > 95%. CAS No. 10080-05-4. Molecular formula: C15H23N3O3S. Mole weight: 325.43.
Glipizide EP Impurity I
Glipizide EP Impurity I is an impurity of Glipizide. Synonyms: 1-Cyclohexyl-3-(p-sulfaMoylphenethyl)urea; 4- [2- [ [ (CyclohexylaMino) carbonyl] aMino] ethyl] benzenesulfonaMide; N-[4- (β -Cyclohexylureidoethyl) benzensulfonyl] N'-Cyclohexylurea; N-[ (Cyclohexylamino) carbonyl]-4-[2-[[ (cyclohexylamino) carbonyl]amino]ethyl]- benzenes. Grades: > 95%. CAS No. 10079-35-3. Molecular formula: C22H34N4O4S. Mole weight: 450.60.
H 151
H 151 is a highly potent, selective STING antagonist, which reduces TBK1 phosphorylation and suppresses human STING palmitoylation. Synonyms: H-151; H151; Urea, N-(4-ethylphenyl)-N'-1H-indol-3-yl-; N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea; N-(4-Ethylphenyl)-N'-1H-indol-3-ylurea; H 151 (pharmacological agent). Grades: ≥98%. CAS No. 941987-60-6. Molecular formula: C17H17N3O. Mole weight: 279.34.
Iso Loratadine
Loratadine impurity. An isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases. Group: Biochemicals. Alternative Names: 4-(8-Chloro-6, 11-dihydro-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-yl)-3, 6-dihydro-1(2H)-pyridinecarboxylic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 170727-59-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
L-755507
L-755,507 is a potent, selective and novel β3-adrenergic receptor (β3-AR) partial agonist with an EC50 value of 0.43 nM. It is over 440-fold selectivity for β3 compared to β1 and β2-adrenergic receptor binding. It has been used to enhance CRISPR-mediated homology-directed repair efficiency for large fragment insertions and for point mutations at 5 μM in human induced pluripotent stem cells. It also has been used to identify signaling pathways activated through β3-adrenergic receptors. It stimulates lipolysis in rhesus adipocytes in vitro. It may also serve as a potential therapeutic target for the treatment of type II diabetes and obesity. Synonyms: L-755507; L 755507; L755507; 4- [ [ (Hexylamino) carbonyl] amino] -N- [4- [2- [ [ (2S) -2-hydroxy-3- (4-hydroxyphenoxy) propyl] amino] ethyl] phenyl] benzenesulfonamide; (S) -4- [ [ (Hexylamino) carbonyl] amino] -N- [4- [2- [ [2-hydroxy-3- (4-hydroxyphenoxy) propyl] amino] ethyl] phenyl] benzenesulfonamide; 1-Hhexyl-3- [4- [ [4- [2- [ [ (2S) -2-hydroxy-3- (4-hydroxyphenoxy) propyl] amino] ethyl] phenyl] sulfamoyl] phenyl] urea. Grades: ≥98% by HPLC. CAS No. 159182-43-1. Molecular formula: C30H40N4O6S. Mole weight: 584.73.
LIMK1 inhibitor BMS 4
LIMK1 inhibitor BMS 4 is a potent LIM kinase 1 (LIMK1; IC50 = 22nM) inhibitor devoid of any cytotoxic side effects. Synonyms: 1-ethyl-3-[5-[6-(4-methoxy-2,6-dimethylphenyl)-2-pyrazin-2-ylpyrimidin-4-yl]-1,3-thiazol-2-yl]urea. Grades: 99%. CAS No. 905298-84-2. Molecular formula: C23H23N7O2S. Mole weight: 461.54.
N-Didesmethyl Cariprazine
N-Didesmethyl Cariprazine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)urea. CAS No. 839712-25-3. Molecular Formula: C19H28Cl2N4O. Mole Weight: 398.16. Catalog: APB839712253.
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