Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Fluxametamide | Fluxametamide, a broad-spectrum insecticide, is an antagonist of GABA- and glutamate-gated chloride channels, with IC50s of 1.95 and 225 nM for M. domestica GABACls and GluCls. Synonyms: 4-(5-(3,5-Dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl)-N-((methoxyimino)methyl)-2-methylbenzamide; Benzamide, 4-(5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl)-N-((methoxyamino)methylene)-2-methyl-; 4-[5-(3,5-Dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-1,2-oxazol-3-yl]-N-[(methoxyimino)methyl]-o-toluamide. Grade: ≥98%. CAS No. 928783-29-3. Molecular formula: C20H16Cl2F3N3O3. Mole weight: 474.26. |  |
| Fluxametamide | Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels , with IC 50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls. Uses: Scientific research. Group: Signaling pathways. CAS No. 928783-29-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108690. |  |
| Fluxapyroxad | analytical standard. Group: Pesticides & metabolites standardspesticides & metabolitespesticides & metabolites. |  |
| Fluxapyroxad | Fluxapyroxad is a synthetic broad-spectrum fungicide for the control of fungal diseases. It works by inhibiting succinate dehydrogenase in complex II of the mitochondrial respiratory chain, resulting in inhibition of spore germination, germ tubes and mycelia growth within the fungus target species [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 907204-31-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-135549. | |
| Fluxofenim | analytical standard. Group: Pesticides & metabolites standardspesticides & metabolitespesticides & metabolites. | |
| Foundry Fluxes | Foundry Fluxes (blended, fused and granular). We offer a variety of products for diverse applications and maintain an extensive inventory at our warehouses to provide prompt shipment and on-time delivery to our customers. |  Worldwide |
| Mattiflux Flux Powder | Mattiflux Flux Powder. Group: Alloys. |  |
| Silver, brazing flux, white paste | Silver, brazing flux, white paste. Group: Alloys. | |
| Soldering flux, liquid | Soldering flux, liquid. Group: Alloys. | |
| Tenacity No. 125 Flux Powder, working range 750-1200°C (1382-2102°F) | Tenacity No. 125 Flux Powder, working range 750-1200°C (1382-2102°F). Group: Alloys. | |
| Tenacity No. 125 Paste, a high temperature flux paste, working range 800-1100°C (1472-2012°F) | Tenacity No. 125 Paste, a high temperature flux paste, working range 800-1100°C (1472-2012°F). Group: Alloys. | |
| Tenacity No. 6 Flux Powder | Tenacity No. 6 Flux Powder. Group: Alloys. | |
| 13,14-dihydro-15-keto prostaglandin D2 | 13,14-dihydro-15-keto prostaglandin D2 is a metabolite of PGD2 which is formed through the 15-hydroxy PGDH pathway. It has been recently identified as a selective agonist for the DP2 receptor. Additionally, 13,14-dihydro-15-keto Prostaglandin D2 has been shown to inhibit ion flux in canine colonic mucosa preparation. Synonyms: 13,14-dihydro-15-keto PGD2; 11,15-dioxo-9S-hydroxy-5Z-prostenoic acid; (Z)-7-[(1R,2R,5S)-5-hydroxy-3-oxo-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid. Grade: ≥95%. CAS No. 59894-07-4. Molecular formula: C20H32O5. Mole weight: 352.5. | |
| 2-Methylthio-ADP Trisodium Salt | 2-Methylthio-ADP trisodium salt is a P2Y1, P2Y12 and P2Y13 agonist. It is used in biological study of activation of P2Y1 P2Y12 and P2Y13 protein promoted purinergic ATP signal transduction mediated calcium flux in podocyte isolated from rat glomerulus. Group: Biochemicals. Alternative Names: 2-(Methylthio)adenosine 5'-Diphosphate Trisodium Salt; 2-MeSADP; 2-Methylthio-ADP. Grades: Highly Purified. CAS No. 475193-31-8. Pack Sizes: 10mg. Molecular Formula: C??H??N?Na?O??P?S, Molecular Weight: 539.24. US Biological Life Sciences. |  Worldwide |
| 3,4-Dimethoxychalcone | 3,4-Dimethoxychalcone is a Caloric restriction mimetics (CRMs). 3,4-Dimethoxychalcone induces the deacetylation of cytoplasmic proteins and stimulates autophagy flux. 3,4-Dimethoxychalcone can be used for cardiac and cancer diseases research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5416-71-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W083373A. | |
| 3-Hydroxy Ipratropium Bromide | 3-Hydroxy Ipratropium Bromide is an extremely efficacious bronchodilator used in studying respiratory ailments such as asthma, chronic obstructive pulmonary disease (COPD) and bronchospasm. Through the impervious blockade of acetylcholine receptors situated within the airways, this pharmacological entity stimulates muscular pacification and optimizes the flux of inspired air. Synonyms: 3-[3-Hydroxy-2-(3-hydroxy-phenyl)-propionyloxy]-8-isopropyl-8-methyl-8-azonia-bicyclo[3.2.1]octane; bromide. Grade: > 95%. Molecular formula: C20H30BrNO4. Mole weight: 428.37. | |
| 6-Azuridine | 6-Azuridine (6-Azauridine) is an orally active purine nucleoside analogue. 6-Azuridine activates autophagic flux , induces Apoptosis that depends on AMPK and p53. 6-Azuridine exhibit both antitumor and antiviral activities [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 6-Azauridine. CAS No. 54-25-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-131611. | |
| 7ACC2 | 7ACC2 did not influence the prothrombin time which, together with a good in vitro ADME profile, supports the potential of this new family of compounds to act as anticancer drugs through inhibition of lactate flux. Synonyms: 7ACC2; 7 ACC2; 7-ACC2. Grade: >98%. CAS No. 1472624-85-3. Molecular formula: C18H15NO4. Mole weight: 309.32. | |
| A317491 ((S)-5-((3-phenoxybenzyl)(1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)benzene-1,2,4-tricarboxylic Acid, P2X3 Purinergic Receptors Antagonist, A317491, P2X2/3 Purinergic Receptors Antagonist, A317491, A 317491) | A potent, selective, and competitive non-nucleotide antagonist of P2X3 and P2X2/3 receptors that blocks receptor-mediated Ca2+ flux (Ki = 22 and 92nM for rat P2X3 and P2X2/3 receptor and 22 and 9nM for human P2X3 and P2X2/3 receptor, respectively). Its R-enantiomer has significantly reduced activity at these receptors. Exhibits high selectivity over other purinergic receptors. Shown to reduce thermal and mechanical hyperalgesia in rat models (ED50 = 10-15uM/kg, s.c). Its anti-nociceptive effects have a rapid on-set and persist for up to 5 hours after sub-cutaneous administration. Also shown to block dorsal root ganglion currents in a dose-dependent manner (IC50 = 15nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 475205-49-3. Pack Sizes: 5mg. Molecular Formula: C??H??NO? xH2O xNa. US Biological Life Sciences. | Worldwide |
| A-317491 sodium salt hydrate | A-317491 sodium salt hydrate is a potent, selective antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. It reduces inflammatory and neuropathic pain by blocking P2X3 and P2X2/3 receptor-mediated calcium flux. Grade: 99%. Molecular formula: C33H29NNaO9. Mole weight: 606.57. | |
| A740003 (N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2, 2-dimethylpropyl) -2- (3, 4-dimethoxyphenyl) acetamide, A 740003, P2X7 Purinegic Receptor, A740003, A740003) | A highly potent, selective, competitive antagonist of P2X7 purinegic receptor (IC50 = 18nM and 40nM, respectively as measured by Bz-ATP-stimulated Ca2+ flux). Does not affect other P2 receptors even at 10uM concentrations. Blocks agonist-evoked IL-1b release (IC50 = 156nM) and pore formation (IC50 = 92nM) in differentiated human THP-1 cells. Also shown to reduce carrageenan and Freund's adjuvant -induced thermal hyperalgesia (ED50 = 38-54mg/kg, i.p) and neuropathic pain induced by chronic constriction injury (CIC) of the sciatic nerve. Group: Biochemicals. Grades: Highly Purified. CAS No. 861393-28-4. Pack Sizes: 5mg. Molecular Formula: C??H??N?O?, Primary Target: P2X7. US Biological Life Sciences. | Worldwide |
| Acetyl Hexapeptide-37 | Acetyl Hexapeptide-37 is a synthetic peptide known for its anti-aging properties and is commonly used as a cosmetic ingredient. It works by enhancing cellular moisture within the skin's surface layers, providing balanced hydration between the skin's layers. This peptide is composed of the amino acids alanine, proline, serine, and glycine, and it has the ability to increase skin hydration by enhancing the expression of aquaporin 3 (AQP3), which is a water channel protein in the skin. The increased expression of AQP3 improves the water flux from the basal layer of the epidermis to the stratum corneum, leading to better skin hydration and health. Synonyms: Ac-SPAGGP-NH2; Acetyl Hexapeptide 37; N-Acetyl-L-seryl-L-prolyl-L-alanyl-glycyl-glycyl-L-prolinamide; (S)-1-(Acetyl-L-seryl)-N-((S)-1-((2-((2-((S)-2-carbamoylpyrrolidin-1-yl)-2-oxoethyl)amino)-2-oxoethyl)amino)-1-oxopropan-2-yl)pyrrolidine-2-carboxamide; Diffuporine; Ac-L-Ser-L-Pro-L-Ala-Gly-Gly-L-Pro-NH2. Grade: ≥95%. CAS No. 1447824-16-9. Molecular formula: C22H35N7O8. Mole weight: 525.56. | |
| AF 353 | AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist. It is a highly potent inhibitor of α,β-meATP-evoked intracellular calcium flux in cell lines expressing recombinant rat and human P2X3 and human P2X2/3 channels. It also blocks human P2X2/3 channel function with marginally reduced potency (pIC50 = 7.3). It significantly reduces this parameter in both groups. It also reduces the inter-contractile interval in control but not in SCI rats. Synonyms: AF353; AF-353; 2,4-Pyrimidinediamine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-; Ro 4; 5-{[5-iodo-2-(1-Methylethyl)-4-(Methyloxy)phenyl]oxy}-2,4-pyrimidinediamine. Grade: >98%. CAS No. 865305-30-2. Molecular formula: C14H17IN4O2. Mole weight: 400.21. | |
| AF353 (P2X3 Purinergic Receptor Antagonist, AF353, P2X2/3 Purinergic Receptor Antagonist, AF353) | A novel, potent, orally bioavailable antagonist of P2X3/P2X2/3 receptors (pIC50 = 8 in human and rat; pIC50 = 7.3 for human P2X2/3 receptor). Shown to be highly brain penetrant with a brain to plasma ratio of 6. Blocks agonist-evoked intracellular Ca2+ flux and inward currents in nanomolar range (10nM to 1uM) in cell lines recombinantly expressing human P2X3 and P2X2/3 receptors. Exhibits desirable pharmacokinetic properties (t1/2 = 1.63 h and Tmax = 30 min). Group: Biochemicals. Grades: Highly Purified. CAS No. 927887-18-1. Pack Sizes: 5mg. Molecular Formula: C??H??ClIN?O?. US Biological Life Sciences. | Worldwide |
| Aluminium phosphate | Aluminium phosphate occurs in nature as the mineral, berlinite. Also, it occurs in nature in minerals, amblygonite, [NaAl(PO4)(OH)]; augelite, [Al2(PO4)(OH)3]; lazulite, [(Mg,Fe)Al2(PO4)2(OH)2]; variscite [(Al,Fe3+)(PO4) 2H2O]; and wavellite, [Al3(OH)3 (PO4)2 5H2O]. It is used as flux for ceramics; as cement in combination with calcium sulfate and sodium silicate; and in the manufacture of special glasses. It is also used in dried gel and therapeutically as an antacid. Product ID: PE-0677. Molecular formula: AlPO4. Mole weight: 121.9529. Category: Antacid; vaccine adjuvant. Product Keywords: Vaccine Adjuvants; PE-0677; Aluminium phosphate. Chemical Name: Aluminium phosphate. Grade: Pharmaceutical grade. Administration route: Accepted for use in human and veterinary vaccines. Dosage Form: Accepted for use in human and veterinary vaccines. Stability and Storage Conditions: Aluminum phosphate adjuvant is stable for at least 2 years when stored at 4-308°C in well-sealed inert containers. It must not be allowed to freeze as the hydrated colloid structure will be irreversibly damaged. Source and Preparation: Aluminum phosphate adjuvant is formed by the reaction of a solution of aluminum chloride and phosphoric acid with alkali hydroxide. Applications: Aluminum Phosphate is an odorless, white crystalline solid which is often used in liquid or gel form. It is used in ceramics, dental cements, cosmetics, paints, paper an |  |
| AM095 | AM095 is a selective LPA 1 receptor antagonist. The IC 50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA 1 -transfected CHO cells is 0.025 and 0.023 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1345614-59-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16039. | |
| AM095 sodium | AM095 is a selective LPA1 receptor antagonist. The IC50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells is 0.025 and 0.023 μM, respectively. Synonyms: AM-095 sodium; AM 095 sodium. Grade: >98%. CAS No. 1345614-59-6. Molecular formula: C27H23N2NaO5. Mole weight: 478.48. | |
| AMD3465 hexahydrobromide | AMD 3465 is a potent and selective antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells. AMD 3465 (50 nM) totally blocks CXCL12-induced calcium mobilization, with an IC50 of 17 nM, but shows no effect on the intracellular calcium fluxes elicited by the CCR5 ligands RANTES, LD78β and MIP-1β in U87.CD4.CCR5 cells. MD3465 was even 10-fold more effective as a CXCR4 antagonist, while showing no interaction whatsoever with CCR5. AMD3465 has the potential to mobilize hematopoietic stem cells. Synonyms: AMD3465; GENZ-644494 hexahydrobromide. Grade: ≥95%. CAS No. 185991-07-5. Molecular formula: C24H38N6·6HBr. Mole weight: 896.07. | |
| AMG 837 | AMG 837 sodium salt is a potent GPR40 agonist with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. It displayed the expected two-fold increase in potency on GPR4 compared to the racemic compound and its activity crossed over to the rat and mouse forms of GPR40. It is a highly potent stimulator of insulin secretion in MIN6 cells with an EC50 comparable to that seen in the aequorin Ca2+-flux assay. It was a potent partial agonist in the calcium flux assay on the GPR40 receptor and potentiated glucose stimulated insulin secretion in vitro and in vivo. Synonyms: AMG-837, AMG837, AMG 837. Grade: >98%. CAS No. 865231-46-5. Molecular formula: C26H21F3O3. Mole weight: 438.44. | |
| AMG 837 sodium salt | AMG 837 sodium salt is a potent GPR40 agonist with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. It displayed the expected two-fold increase in potency on GPR4 compared to the racemic compound and its activity crossed over to the rat and mouse forms of GPR40. It is a highly potent stimulator of insulin secretion in MIN6 cells with an EC50 comparable to that seen in the aequorin Ca2+-flux assay. It was a potent partial agonist in the calcium flux assay on the GPR40 receptor and potentiated glucose stimulated insulin secretion in vitro and in vivo. Synonyms: AMG-837 sodium; AMG837 sodium; AMG 837 sodium; AMG-837 sodium salt. Grade: >98%. CAS No. 865231-45-4. Molecular formula: C26H20F3NaO3. Mole weight: 460.42. | |
| Ammonium Chloride | White crystalline salt, soluble in water. Uses: fertilizers, batteries, flux in metalwork. Group: halide salt. Alternative Names: Sal Ammoniac. CAS No. 12125-02-9. |  |
| Antibacterial agent 67 | Antibacterial agent 67 (IC50 = 0.03 μM) has a great enzyme-inhibiting activity on succinate dehydrogenase than fluxapyroxad (IC50 = 4.40 μM). Synonyms: 3-(difluoromethyl)-N-(4'-((2,6-difluorophenyl)diazenyl)-3',5'-difluoro-[1,1'-biphenyl]-2-yl)-1-methyl-1H-pyrazole-4-carboxamide. CAS No. 2488900-01-0. Molecular formula: C24H15F6N5O. Mole weight: 503.40. | |
| AZD2423 | AZD2423 is a potent, selective, orally bioavailable and non-competitive negative allosteric regulator of CCR2 chemokine receptor with an IC50 of 1.2 nM for CCR2 Ca2+ flux. Synonyms: N-(4-Chloro-3-fluorophenyl)-4-{[(2R)-4-(2-methyl-2-propanyl)-2-piperazinyl]carbonyl}-1-piperazinecarboxamide; 1-Piperazinecarboxamide, N-(4-chloro-3-fluorophenyl)-4-[[(2R)-4-(1,1-dimethylethyl)-2-piperazinyl]carbonyl]-; AZD-2423. Grade: ≥98%. CAS No. 1229603-37-5. Molecular formula: C20H29ClFN5O2. Mole weight: 425.93. | |
| BI 639667 | BI 639667 (compound 19n), a third azaindazole series compound, is a CCR1 antagonist, with an IC 50 of 1.8 nM in Ca 2+ flux assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCR1 antagonist 8. CAS No. 1295298-26-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-120588. | |
| BMS-935177 | BMS-935177 is a potent and selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 3 nM and demonstrates good kinase selectivity. It is more potent against BTK than other kinase, including the other Tec family kinases (TEC, BMX, ITK, and TXK) over which the compound is between 5- and 67-fold selective. BMS-935177 inhibited calcium flux in human Ramos B cells with IC50 of 27 nM and inhibited CD69 surface expression in peripheral B cells stimulated with anti-IgM and anti-IgG. Synonyms: BMS-935177; BMS935177. Grade: ≥98%. CAS No. 1231889-53-4. Molecular formula: C31H26N4O3. Mole weight: 502.56. | |
| BODIPY-Cholesterol | BODIPY-cholesterol is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 505/515 nm)[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 878557-19-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125746. | |
| Boric Acid Granular | Boric acid granular, alternately termed orthoboric acid and boracic acid, is a naturally existing compound encompassing the elements boron, oxygen, and hydrogen, denoted chemically as (H3BO3). This substance is harnessed as a fluxing agent and frequently employed as a natural insect repellent as well. Uses: Adhesives & Cements, Corrosion Inhibitors, Electroplating, Paint & Coatings, Pest Control. Alternative Names: Orthoboric Acid. CAS No. 10043-35-3. Pack Sizes: 50lb. |  USA |
| Boric anhydride | Boric anhydride. Uses: Boron oxide was used as the intermediate glass layer at a bonding temperature of 450°c. in preparation of fluxes; component of enamels and glass; catalyst in organic reaction. in metallurgy; in analysis of silicates to determine sio2 and alkalies; in blowpipe analysis. Group: Electronic materials. Alternative Names: Boric anhydride, 99.98% trace metals basis; JKWMSGQKBLHBQQ-UHFFFAOYSA-N; Diboron trioxide; Boric anhydride, purum p.a., >=97.0% (T); CHEBI:30163; boron(III) oxide; Boric anhydride, puriss. p.a., >=98% (T); AKOS015903863; FT-0694863; Boric anhydride, Vetec(TM) reagent grade, 98%. CAS No. 1303-86-2. Product ID: oxo(oxoboranyloxy)borane. Molecular formula: 69.617g/mol. Mole weight: B2O3;B2O3;B2O3. B(=O)OB=O. InChI=1S/B2O3/c3-1-5-2-4. JKWMSGQKBLHBQQ-UHFFFAOYSA-N. | |
| Boron Trioxide | Boron oxide appears as colorless, semi-transparent glassy lumps or hard white odorless crystals. Mp 450°C; bp: 1860°C. Density: 2.46 g cm-3. Moderately soluble in water. Used as an insecticide; as the starting material for the synthesis of other boron compounds; as a fluxing agent in enamels and glasses; and in mixture with 2-6% boron nitride, as a bonding agent in the hot isostatic pressing of boron nitride ceramics.;DryPowder; DryPowder, PelletsLargeCrystals; PelletsLargeCrystals;WHITE HYGROSCOPIC POWDER OR GRANULES;Colorless, semitransparent lumps or hard, white, odorless crystals.;Colorless, semitransparent lumps or hard, white, odorless crystals. Group: Glass additives. Product ID: oxo(oxoboranyloxy)borane. Molecular formula: 69.63g/mol. Mole weight: B2O3;B2O3;B2O3. B(=O)OB=O. InChI=1S/B2O3/c3-1-5-2-4. JKWMSGQKBLHBQQ-UHFFFAOYSA-N. | |
| Candidalysin | Candidalysin is a cytolytic peptide toxin, which is initially isolated from Candida albicans and exhibits virulent and avirulent characters. Candidalysin activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) of host cells, activates matrix metalloproteinase ( MMP ) and calcium flux, resulting in inflammatory responses and recruitment of immune cells. Candidalysin exhibits cytotoxicity by dealing membran damage to host cells [1]. Uses: Scientific research. Group: Peptides. CAS No. 1906866-53-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10408. | |
| CCR1 antagonist 9 | CCR1 antagonist 9 is a potent and selective antagonist of CCR1 with an IC50? of? 6.8 nM in calcium flux assay. Synonyms: 1-(4-Fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid (2-methanesulfonyl-pyridin-4-ylmethyl)-amide; CCR1 inhibitor 19e; 1H-Pyrazolo[3,4-c]pyridine-4-carboxamide, 1-(4-fluorophenyl)-N-[[2-(methylsulfonyl)-4-pyridinyl]methyl]-; 1-(4-Fluorophenyl)-N-{[2-(methylsulfonyl)-4-pyridinyl]methyl}-1H-pyrazolo[3,4-c]pyridine-4-carboxamide. Grade: ≥95%. CAS No. 1220026-26-5. Molecular formula: C20H16FN5O3S. Mole weight: 425.44. | |
| CCR4 antagonist 2 | CCR4 antagonist 2 is a potent and orally bioavailable small molecule CCR4 antagonist, with IC50s of 40 and 70 nM for Ca2+ flux and (chemotaxis) CTX, respectively. It inhibits Treg trafficking into the tumor microenvironment without suppressing the number of Treg in healthy tissue. Synonyms: 1H-Pyrazolo[3,4-b]pyrazine-3-carbonitrile, 1-[(1R)-1-(2,4-dichlorophenyl)ethyl]-6-[(4S,5R)-4-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-5-methyl-1-cyclohexen-1-yl]-; 1-[(1R)-1-(2,4-Dichlorophenyl)ethyl]-6-{(4S,5R)-4-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-5-methyl-1-cyclohexen-1-yl}-1H-pyrazolo[3,4-b]pyrazine-3-carbonitrile. Grade: ≥97%. CAS No. 2206788-99-8. Molecular formula: C26H28Cl2N6O. Mole weight: 511.45. | |
| CCR4 antagonist 3 | CCR4 antagonist 3, a potent, selective and orally active CCR4 antagonist, has a novel piperidinyl-azetidine motif with IC50s of 22 nM and 50 nM in the calcium flux and CTX assay. It has antitumor activity. Synonyms: 1H-Pyrazolo[3,4-b]pyrazine-3-carbonitrile, 1-[(1R)-1-(2,4-dichlorophenyl)ethyl]-6-[3-[(3R)-1-(2-hydroxyethyl)-3-piperidinyl]-1-azetidinyl]-. CAS No. 2174938-70-4. Molecular formula: C24H27Cl2N7O. Mole weight: 500.42. | |
| CCR4 antagonist 3 hydrochloride | CCR4 antagonist 3 hydrochloride, a potent, selective and orally active CCR4 antagonist, has a novel piperidinyl-azetidine motif with IC50s of 22 nM and 50 nM in the calcium flux and CTX assay. It has antitumor activity. Synonyms: 1H-Pyrazolo[3,4-b]pyrazine-3-carbonitrile, 1-[(1R)-1-(2,4-dichlorophenyl)ethyl]-6-[3-[(3R)-1-(2-hydroxyethyl)-3-piperidinyl]-1-azetidinyl]-, hydrochloride (1:x). Grade: ≥98%. CAS No. 2174938-71-5. Molecular formula: C24H27Cl2N7O.xHCl. Mole weight: 500.42 (free base). | |
| CE3F4 | CE3F4 is a noncompetitive Epac1 inhibitor that inhibits Epac-induced Rap activation and prevents isoprenaline-induced autophagy flux in cardiomyocytes. It has no effect on PKA activity in the presence of cAMP. Synonyms: CE3F4; CE-3-F-4; CE 3 F 4; CE-3F4; CE 3F4; 5,7-Dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde. Grade: ≥98% by HPLC. CAS No. 143703-25-7. Molecular formula: C11H10Br2FNO. Mole weight: 351.01. | |
| Celikalim | Celikalim is s ATP-sensitive potassium channel agonist originated by Wyeth. It increases K+ outward flux in dog and human airway smooth muscle. But clinical trials for Hypertension, Ischaemic heart disorders and Thrombosis was discontinued. Uses: Hypertension; ischaemic heart disorders; thrombosis. Synonyms: Way-120,491; Way120491; Way-120491; Way 120491; Celikalim; 2-[(3S,4R)-3-hydroxy-2,2-dimethyl-6-(trifluoromethoxy)-3,4-dihydrochromen-4-yl]-3H-isoindol-1-one. Grade: 98%. CAS No. 124916-54-7. Molecular formula: C20H18F3NO4. Mole weight: 393.36. | |
| Clarithromycin | Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4 -catalyzed triazolam alpha-hydroxylation with the IC 50 ( K i ) value of 56 (43) μM [2]. Clarithromycin significantly inhibits the HERG potassium current [3].Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81103-11-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-17508. | |
| Clarithromycin | Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with the IC50 (Ki) value of 56 (43) μM. Clarithromycin significantly inhibits the HERG potassium current.Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Erythromycin, 6-O-methyl-. Product Category: Inhibitors. CAS No. 81103-11-9. Molecular formula: C38H69NO13. Mole weight: 747.95. Purity: 0.999. Product ID: ACM81103119-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Clarithromycin (Standard) | Clarithromycin (Standard) is the analytical standard of Clarithromycin. This product is intended for research and analytical applications. Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with the IC50 (Ki) value of 56 (43) μM [2]. Clarithromycin significantly inhibits the HERG potassium current [3].Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81103-11-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-17508R. | |
| DCAP | DCAP is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP blocks autophagy at the late stages by preventing autophagolysosome maturation and interrupting the autophagic flux [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500015-20-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136068. | |
| Diatomaceous Earth | Diatomaceous Earth. Synonyms: Diatomaceous earth, flux-calcined. CAS No. 68855-54-9. Pack Sizes: 1 kg, 5 kg. Product ID: CDC10-0011. Molecular formula: O2Si. Category: Cosmetic Chemical Abrasives. Product Keywords: Cosmetic Ingredients; Cosmetic Chemical Abrasives; Diatomaceous Earth; CDC10-0011; 68855-54-9; O2Si; Diatomaceous earth, flux-calcined; 272-489-0; MFCD00132803; 68855-54-9. EC Number: 272-489-0. Physical State: Powder. Quality Level: 100. Storage: Please store the product under the recommended conditions in the Certificate of Analysis. Boiling Point: N/A. Melting Point: >450°C. Density: 0.47 g/cm3 (loose weight)(lit.). Product Description: Diatomaceous earth is natural amorphous silica formed from the fossilized skeletons of diatoms. It has high water and oil absorption ability. | |
| Diatomaceous Earth FW 12 | Celatom FW-12 Diatomaceous Earth, also known as "DE" or "DE Powder," serves as a filter aid employed across various applications. Its primary application involves serving as a precoat in industrial wastewater filtration processes. This precoat enhances the concentration of solids within the sludge while simultaneously reducing the overall volume of sludge requiring disposal. Celatom FW-12 Diatomaceous Earth is a flux-calcined diatomaceous earth (DE) material, displaying a color spectrum from bright white to light pink. It exists as an odorless solid with a pH value of 10 in a 10% suspension. In terms of particle size, it exhibits a sieve analysis (Tyler) result of 3-15% retention at 150 Mesh (>105 microns), with less than 1% being soluble in water. Furthermore, its filter offers a permeability range of 650-1150 millidarcies. Uses: Filter Aid. Alternative Names: Diatomaceous Earth, Diatomaceous Earth Flux Calcined. Grades: Tech. CAS No. 68855-54-9, 14464-46-1. Pack Sizes: 50 lb. | USA |
| Diatomaceous Earth FW 14 | Diatomaceous Earth FW 14 is a filter aid used in a variety of applications, such as swimming pools. When Diatomaceous Earth is introduced into the pool filter system, it coats the filter cloth. As water passes over the filter grids, the DE particles capture even the smallest suspended dirt particles. DE Powder also works wonders in wine making. The pores within and between the cell walls of Diatomaceous Earth are so small, they trap bacteria, clay particles, some viruses, and other suspended solids from liquids. This leaves the wine cleaner and with drastically reduced solids and contaminant levels. It is also used in wastewater as the primary use is as a precoat in the filtration of industrial wastewater. Uses: Filter Aid. Alternative Names: Diatomaceous Earth, Diatomaceous Earth Flux Calcined. Grades: Tech. CAS No. 68855-54-9, 14464-46-1. Pack Sizes: 50 lb. | USA |
| Disodium tetraborate | Sodium Tetraborate, is an important boron compound, which has a wide variety of applications. It is a component of many detergents, cosmetics, and enamel glazes. It is also used to make buffer solutions in biochemistry, as a fire retardant, as an anti-fungal compound for fiberglass, as a flux in metallurgy, neutron-capture shields for radioactive sources, a texturing agent in cooking, and as a precursor for other boron compounds. Uses: Designed for use in research and industrial production. Additional or Alternative Names: boricin;jaikin;borascu;sodium tetrabotare;BORAX. Product Category: Heterocyclic Organic Compound. Appearance: White solid. CAS No. 1330-43-4. Molecular formula: B4Na2O7. Density: 2.367. ECNumber: 215-540-4. Product ID: ACM1330434. Alfa Chemistry ISO 9001:2015 Certified. | |
| Dizocilpine | Dizocilpine (MK-801), a potent anticonvulsant, is a selective and non-competitive NMDA receptor antagonist, with a K d of 37.2 nM in rat brain membranes. Dizocilpine acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca 2+ flux [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-801. CAS No. 77086-21-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15084B. | |
| EACC | EACC is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 864941-31-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-129111. | |
| Eldelumab | Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease[1][2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS-936557; MDX-1100. CAS No. 946414-98-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99190. | |
| Eldelumab | Eldelumab is a humanized anti-CXCL10 (IP-10) monoclonal antibody that binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab has been use for the treatment of ulcerative colitis. Synonyms: BMS-936557; MDX-1100. CAS No. 946414-98-8. | |
| Enzyme for Cleaning apple or pear juice | Clean & maintain permeate flux-rate filter membranes. Applications: Apples & pears processing enzymes. Group: Enzymes. Synonyms: Cleaning apple or pear juice enzyme; Apples & Pears Processing Enzymes; Enzyme for Cleaning; Cleaning; apple; pear juice; Enzyme for Cleaning apple or pear juice enzyme; FJE-1421. Enzyme for apple or pear juice. Appearance: powder or liquid. Cleaning apple or pear juice enzyme; Apples & Pears Processing Enzymes; Enzyme for Cleaning; Cleaning; apple; pear juice; Enzyme for Cleaning apple or pear juice enzyme; FJE-1421. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form) or subject to client requirement. Cat No: FJE-1421. |  |
| FG 7142 | FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor ( K i =91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit ( EC 50 = 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZK 39106; LSU-65. CAS No. 78538-74-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-100991. | |
| Flunarizine-d8 Dihydrochloride | Flunarizine-d8 Dihydrochloride. Group: Biochemicals. Alternative Names: 1-[Bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine-d8 Hydrochloride; Dinaplex-d8; Flugeral-d8; Flunagen-d8; Flunarl-d8; Fluxarten-d8; Gradient-d8; Issium-d8; Mondus-d8; R 14950-d8. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C26H20D8Cl2F2N2, Molecular Weight: 485.47. US Biological Life Sciences. | Worldwide |
| Flunarizine Dihydrochloride | ?98% (TLC). Group: Fluorescence/luminescence spectroscopyapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Mondus, Flunagen, (E)-1-[Bis(4-fluorophenyl)methyl]-4-cinnamylpiperazine dihydrochloride, Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propenyl]-, dihydrochloride (9CI), R 14950, Piperazine, 1-[bis(p-fluorophenyl)methyl]-4-cinnamyl-, dihydrochloride, (E)- (8CI), Flugeral, Dinaplex, Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)-, dihydrochloride, (E)-, Flunarizine hydrochloride, Flunarl, Flunarizine dihydrochloride, Gradient,Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride (1:2), Issium, Fluxarten. | |
| Flunarizine Dihydrochloride | Calcium channel blocker; fluorinated derivative of Cinnarizine. Vasodilator (cerebral and peripheral). Group: Biochemicals. Alternative Names: 1-[Bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine Hydrochloride; Dinaplex; Flugeral; Flunagen; Flunarl; Fluxarten; Gradient; Issium; Mondus; R 14950. Grades: Highly Purified. CAS No. 30484-77-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| GLPG2938 | GLPG2938 is a potent and selective S1P2 antagonist that can be used for the study of idiopathic pulmonary fibrosis. It inhibits S1P-induced calcium flux in CHO cells overexpressing human S1P2 (IC50 = 8.8 nM), inhibits S1P-induced IL-8 release in HFL1 cells (IC50 = 0.6 nM) and S1P-induced contraction of human lung fibroblasts. Synonyms: 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea; MUN96006; 1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridinyl]-3-({5-methyl-6-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-3-pyridazinyl}methyl)urea; Urea, N-[2-ethoxy-6-(trifluoromethyl)-4-pyridinyl]-N'-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-3-pyridazinyl]methyl]-. Grade: ≥98%. CAS No. 2130996-00-6. Molecular formula: C20H19F6N7O2. Mole weight: 503.40. | |
| Gold | insulated wire, 1m, conductor diameter 0.025mm, insulation thickness 0.002mm, PTFE (polytetrafluoroethylene) insulation, 99.99%. Uses: Gold based neutron flux monitors may use gold foils. au foils may be used to form a ausn/au joint system for opto-electronic chips. modified gold foil electrode may be used to study heterogeneous electron transfer properties of biological electron transfer proteins.3 electrodeposited polycrystalline palladium-nickel alloy on gold foils may be investigated for the enhanced catalytic behavior of the alloy. Group: Metal nano dispersion. Alternative Names: Gold Powder,Gold black,Gold element. CAS No. 7440-57-5. Product ID: gold. Molecular formula: 196.97. Mole weight: Au;Au. [Au]. | |
| Gold | insulated wire, 1m, conductor diameter 0.025mm, insulation thickness 0.002mm, PTFE (polytetrafluoroethylene) insulation, 99.99%. Uses: Gold based neutron flux monitors may use gold foils. au foils may be used to form a ausn/au joint system for opto-electronic chips. modified gold foil electrode may be used to study heterogeneous electron transfer properties of biological electron transfer proteins.3 electrodeposited polycrystalline palladium-nickel alloy on gold foils may be investigated for the enhanced catalytic behavior of the alloy. Group: Self assembly and lithographynanoparticlessubstrates and electrode materials vapor deposition precursors. Alternative Names: Gold Powder,Gold black,Gold element. CAS No. 7440-57-5. Pack Sizes: 1.5 g in rigid mailer. Product ID: gold. Molecular formula: 196.97. Mole weight: Au;Au. [Au]. 1S/Au. PCHJSUWPFVWCPO-UHFFFAOYSA-N. | |
| GW406108X | GW406108X is a Kif15 (Kinesin-12) inhibito. GW406108X inhibits ULK1 and autophagy flux in cells. Synonyms: GW108X. CAS No. 1644443-92-4. Molecular formula: C20H11Cl2NO4. Mole weight: 400.21. | |
| Heparin | Heparin, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. The common form is the sodium salt form. Synonyms: [2-Deoxy-2-sulfoamino-6-O-sulfo-4-O-(2-O-sulfo-a-L-idopyranuronosyl)-a-D-glucopyranose]n; Adomiparin; Ardeparin; Arteven; AVE 5026; Bemiparin; Centaxarin; Certoparin; Clevarin; Clivarin; Clivarine; CY 216; CY 222; Dalteparin; Deligoparin; F 202; Fluxum; FR 860; Fragmin A; Fragmin B; Fraxiparin; Gammaparin; H 5284; H 9399; Hapacarin; Heparin subcutan; Heparin sulfate; Heparinic acid; Heparins; KB 101; Leparan; LipoHep Forte; Livaracine; M 118; M 402 (heparin); Mono-embolex; Multiparin; Nadroparin; Nadroparine; Necuparanib; Novoheparin; Octaparin; OP 386; OP 622; Pabyrn; Parnaparin; Parvoparin; Reviparin; Sandoparin; Semuloparin; Subeparin; Sublingula; Tafoxiparin; Tinzaparin; Triofiban; Vetren; Vitrum AB; α-Heparin. Grade: >98%. CAS No. 9005-49-6. | |
| Hydroxychloroquine | Hydroxychloroquine (HCQ) is a synthetic oral antimalarial drug that can be used in the study of malaria and autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. Hydroxychloroquine is a potent autophagic flux inhibitor with antiviral activity (such as SARS-CoV-2 virus) that inhibits Toll-like receptor 7/9 ( TLR7/9 ) signaling [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. CAS No. 118-42-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-W031727. | |
| Kb-r7943 mesylate | KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM. KB-R7943 mesylate induces cancer cell death via activating the JNK pathway and blocking autophagic flux. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 182004-65-5. Molecular formula: C16H17N3O3S.CH3SO3H. Mole weight: 427.5. Purity: >99 %. Canonical SMILES: NC(SCCC1=CC=C(OCC2=CC=C([N+]([O-])=O)C=C2)C=C1)=N.CS(=O)(O)=O. Product ID: ACM182004655. Alfa Chemistry ISO 9001:2015 Certified. | |
Our database is helping our users find suppliers everyday.
