Fungal Enzyme Suppliers USA
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Product | Description | |
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2,3,4,6-Tetra-O-benzoyl-b-D-glucopyranosyl fluoride Quick inquiry Where to buy Suppliers range | 2,3,4,6-Tetra-O-benzoyl-b-D-glucopyranosyl fluoride, a widely used compound in the synthesis of complex carbohydrates and glycoproteins, can serve as an ideal glycosyl donor in the enzymatic synthesis of oligosaccharides and glycosides. Its multifaceted properties are exemplified by its ability to exhibit potential inhibitory activity against numerous bacterial and fungal pathogens, indicating its prospective role as a therapeutic agent for addressing a spectrum of infectious diseases. Synonyms: [(2R,3r,4s,5r,6s)-3,4,5-tribenzoyloxy-6-fluoro-tetrahydropyran-2-yl]methyl benzoate; 2,3,4,6-Tetra-O-benzoyl-1-deoxy-1-fluoro-beta-D-glucopyranoside; [(2R,3R,4S,5R,6S)-3,4,5-Tribenzoyloxy-6-fluorooxan-2-yl]methyl benzoate; AKOS030211026; 2,3,4,6-Tetra-o-benzoyl-beta-d-glucopyranosyl fluoride. CAS No. 4163-40-0. Molecular formula: C34H27FO9. Mole weight: 598.59. | |
2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid Quick inquiry Where to buy Suppliers range | 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid, a promising antifungal agent, possesses potent activity against Candidiasis and Aspergillosis. The compound targets 3-ketoacyl-ACP synthase III (FabH), a key enzyme in the biosynthesis of fungal fatty acids, and reduces fungal growth by inducing cellular membrane disruption through inhibition of FabH activity. With its unique mode of action, 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid stands as a notably effective potential antifungal therapeutic candidate. Synonyms: 2H,3H-Thieno[3,4-B][1,4]dioxine-2-carboxylic acid; EDOT carboxylic acid; Carboxyedot. CAS No. 955373-67-8. Molecular formula: C7H6O4S. Mole weight: 186.181. | |
(2Z)-1-Chloro-6,6-dimethyl-2-hepten-4-yne Quick inquiry Where to buy Suppliers range | (2Z)-1-Chloro-6,6-dimethyl-2-hepten-4-yne is a byproduct in the synthesis of Terbinafine Hydrochloride (T107500); an orally active, antimycotic allylamine related to Naftifine. It is a specific inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Also antifungal. Group: Biochemicals. Grades: Highly Purified. CAS No. 635708-74-6. Pack Sizes: 10mg, 100mg. Molecular Formula: C?H??Cl, Molecular Weight: 156.65. US Biological Life Sciences. | Worldwide |
4-Methylumbelliferyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-galactopyranoside Quick inquiry Where to buy Suppliers range | 4-Methylumbelliferyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-galactopyranoside, a vital compound utilized in biomedical research, exhibits immense intricacy. Its fluorigenic substrate properties make it indispensable in studying chitinase activity, especially in relation to carbohydrate metabolism enzymes. This exceptional compound finds extensive utility in assays dedicated to comprehending the pathogenesis of diverse ailments, comprising fungal infections and inflammatory disorders. Synonyms: 4-Methylumbelliferyl 2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-beta-D-Galactopyranoside; 4-Methylumbelliferyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-galactopyranoside; [(2R,3R,4R,5R,6S)-5-acetamido-3,4-diacetyloxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl acetate; (2R,3R,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)tetrahydro-2H-pyran-3,4-diyl diacetate; W-200973; 4-Methylumbelliferyl 2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-?-D-Galactopyranoside; [(2R,3R,4R,5R,6S)-3,4-bis(acetyloxy)-5-acetamido-6-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]oxan-2-yl]methyl acetate. CAS No. 124167-46-0. Molecular formula: C24H27NO11. Mole weight: 505.47. | |
4-Methylumbelliferyl phosphocholine Quick inquiry Where to buy Suppliers range | 4-Methylumbelliferyl phosphocholine, a highly sought-after fluorescent substrate within the biomedical industry, boasts immense significance in elucidating the intricacies surrounding phosphocholine-hydrolyzing enzymes. Touted for its efficacy in ascertaining the activity of microbial phospholipases, pivotal actors in the realm of bacterial and fungal pathogenesis, this substrate undeniably opens Pandora's box of insights into the multifaceted mechanics governing diverse infectious diseases. CAS No. 97055-84-0. Molecular formula: C15H20NO6P. Mole weight: 341.30. | |
Anidulafungin Quick inquiry Where to buy Suppliers range | Anidulafungin, is a semisynthetic echinocandin that inhibits glucan synthase, an enzyme important in the formation of (1?3)-β-D-glucan, a major fungal cell wall component, and thus is used as an antifungal drug. Synonyms: Eraxis; Ecalta; LY303366; 1-[(4R,5R)-4,5-dihydroxy-N2-[[4''-(pentyloxy)[1,1':4',1''-terphenyl]-4-yl]carbonyl]-L-ornithine]-echinocandin B. Grades: >98%. CAS No. 166663-25-8. Molecular formula: C58H73N7O17. Mole weight: 1140.24. | |
Aranorosin Quick inquiry Where to buy Suppliers range | Aranorosin is a fungal metabolite originally isolated from P. roseus and an inhibitor of anti-apoptotic functions regulated by Bcl-2. It has antimicrobial activity against B. subtilis, A. niger, and C. albicans when used at a concentration of 1 mg/ml. Aranorosin also reduces viability in apoptosis-resistant HeLa/Bcl-2 cells. Aranorosin also inhibits enzyme AAC(6')/APH(2'') which plays a role in arbekacin (ABK)-resistance in MRSA. Synonyms: Spiro[4,8-dioxatricyclo[5.1.0.03,5]octane-2,2'(3'H)-furan], 2,4-dodecadienamide deriv.; Aranorosine. Grades: ≥95%. CAS No. 117184-53-9. Molecular formula: C23H33NO6. Mole weight: 419.51. | |
Aureobasidin A Quick inquiry Where to buy Suppliers range | Aureobasidin A is an orally available cyclic depsipeptide antibiotic produced by Aureobasidium pullulans that is a fungicide at low concentrations. Aureobasidin A inhibits inositol phosphorylceramide synthase, an enzyme that catalyzes a key step in fungal sphingolipid biosynthesis. This may inhibit fungal cell growth. Uses: Microbial Fermentation Products. CAS No. 127785-64-2. Product ID: MFP-034. | |
BIBB 515 Quick inquiry Where to buy Suppliers range | 2,3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. BIBB 515 is a selective and potent inhibitor of 2,3-oxidosqualene cyclase (OSC) with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. It is concluded that the lipid-lowering effect of BIBB 515 is mainly the result of an inhibition of LDL production rather than due to an increase in LDL catabolism. OSC inhibitors may offer a novel approach for lipid-lowering therapy. Synonyms: BIBB-515; BIBB515. Grades: ≥98%. CAS No. 156635-05-1. Molecular formula: C22H21ClN2O2. Mole weight: 380.9. | |
Cedrol Quick inquiry Where to buy Suppliers range | Cedrol is a bioactive sesquiterpene, a potent competitive inhibitor of cytochrome P-450 (CYP) enzymes. Cedrol inhibits CYP2B6-mediated bupropion hydroxylase and CYP3A4-mediated midazolam hydroxylation with Ki of 0.9 μM and 3.4 μM, respectively. Cedrol also has weak inhibitory effect on CYP2C8, CYP2C9, and CYP2C19 enzymes. Cedrol is found in cedar essential oil and poetesses anti-septic, anti-inflammatory, anti-spasmodic, tonic, astringent, diuretic, insecticidal, and anti-fungal activities. Group: Biobased Products. Alternative Names: Cypress camphor. Grades: 99%. CAS No. 77-53-2. Product ID: BBC77532. Molecular formula: C15H26O. Mole weight: 222.37. IUPAC Name: (1S, 2R, 5S, 7R, 8R)-2, 6, 6, 8-Tetramethyltricyclo[5.3.1.01, 5]undecan-8-ol. Appearance: Pale yellow to yellow green solid. Density: 0.9479 g/cm³. SMILES: CC1CCC2C13CCC(C(C3)C2(C)C)(C)O. | |
Cellobiose-6'-phosphate Quick inquiry Where to buy Suppliers range | Cellobiose-6'-phosphate, an imperative intermediary in the intricate process of carbohydrate metabolism, manifests as a formidable substrate for an array of enzymes engaged in the biosynthesis of cellulose, a fundamental constituent of plant cell walls. Its remarkable aptitude to elicit cellulose synthesis endows Cellobiose-6'-phosphate with a momentous function in the advancement of anti-fungal medicaments that diligently target cellulose synthesis pathways. Molecular formula: C12H23O14P. Mole weight: 422.28. | |
Citrinin Quick inquiry Where to buy Suppliers range | Citrinin is a quinonemethine mycotoxin produced by diverse fungal genera, including Aspergillus and Penicillium. Citrinin has been extensively investigated. It is a potent nephrotoxin with hepatoxic and teratogenic activity. It is the causative agent of Balkan nephropathy and yellow rice fever in humans. At the molecular level, citrinin exhibits a range of effects including free radical damage to DNA and disruption to a wide variety of mitochrondrial membrane-bound enzymic activities and structural integrity. Specifically, citrinin is an inhibitor of NADH dehydrogenase in the mitochondrial electron transport chain and this action is responsible for recent reports of citrinin's apoptotic activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 518-75-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Dehydrophenylahistin Quick inquiry Where to buy Suppliers range | Dehydrophenylahistin are two dehydrogenated products produced by the enzymatic conversion of the fungal metabolite (-)-phenylhistidine [(-)-phenylahistin] through the cell-free extract of Streptomyces albulus KO23. It can inhibit the first lysis of sea urchin embryos. Molecular formula: C20H20N4O2. Mole weight: 348.40. | |
Ethyl-2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-thioglucopyranoside Quick inquiry Where to buy Suppliers range | Ethyl-2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-thioglucopyranoside is a potent compound used in biomedicine for various purposes. It has shown promising results in the treatment of multiple drug-resistant bacteria and fungal infections. Additionally, this product is used as a tool compound to study carbohydrate metabolism and enzymatic mechanisms involved in glycosylation processes, facilitating advancements in drug design and development. CAS No. 49810-41-5. | |
Ethyl 4,6-O-benzylidene-D-thiomannopyranoside Quick inquiry Where to buy Suppliers range | Ethyl 4,6-O-benzylidene-D-thiomannopyranoside is a biomedical product exhibiting its ability to inhibit specific enzymes involved in cancer growth. Additionally, this compound has shown promising results in the research of bacterial and fungal infections by disrupting their essential cellular pathways. Synonyms: Ethyl 4,6-O-[(R)-phenylmethylene]-1-thio-alpha-D-mannopyranoside; Ethyl 4,6-O-benzylidene-D-thiomannopyranoside; DTXSID701187070; (2R,4aR,6R,7S,8R,8aS)-6-ethylsulfanyl-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine-7,8-diol. CAS No. 142924-31-0. Molecular formula: C15H20O5S. Mole weight: 312.38. | |
Fungal Amylase Quick inquiry Where to buy Suppliers range | Fungal Amylase. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS008302. Format: Neat. Product Type: Other. Shipping: Room Temperature. | |
Fungal Lipase Quick inquiry Where to buy Suppliers range | Fungal Lipase. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS008303. Format: Neat. Product Type: Other. Shipping: Room Temperature. | |
Fungal Protease Quick inquiry Where to buy Suppliers range | Fungal Protease. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS008304. Format: Neat. Product Type: Other. Shipping: Room Temperature. | |
Hydroxy Terbinafine Quick inquiry Where to buy Suppliers range | A metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Phenyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside Quick inquiry Where to buy Suppliers range | Phenyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is a promising biomedical product arising by modifying glucose. This compound exhibits intriguing characteristics as it hinders various enzyme activities linked to bacterial and fungal infections. CAS No. 13089-21-9. Molecular formula: C20H25NO9. Mole weight: 423.41. | |
Posaconazole Quick inquiry Where to buy Suppliers range | Anti-fungal agent; sterol α-demethylase inhibitor. Posaconazole is a highly potent broadspectrum antifungal drug. It blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase resulting in accumulation of methylated sterol precursors. In contrast to other antifungal azoles, posaconazole has been reported not to induce the efflux pump mechanism. Posaconazole was able to produce a parasitological cure in a mouse model of the chronic stage of Chagas disease. Group: Biochemicals. Alternative Names: 2, 5-Anhydro-1, 3, 4-trideoxy-2-C- (2, 4-difluorophenyl) -4- [ [4- [4- [4- [1- [ (1S, 2S) -1-ethyl-2-hydroxypropyl] -1, 5-dihydro-5-oxo-4H-1, 2, 4-triazol-4-yl] phenyl] -1-piperazinyl] phenoxy] methyl] -1- (1H-1, 2, 4-triazol-1-yl) -D-threo-pentitol; Noxafil; Sch 56592. Grades: Highly Purified. CAS No. 171228-49-2. Pack Sizes: 250mg, 500mg, 1g, 5g. Molecular Formula: C??H??F?N?O?, Molecular Weight: 700.78. US Biological Life Sciences. | Worldwide |
Posaconazole hydrate Quick inquiry Where to buy Suppliers range | Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole strongly inhibits 14-alpha demethylase, a cytochrome P450-dependent enzyme. Posaconazole is a sterol C14? demethylase inhibitor with an IC50 of 0.25 nM. Inhibition of 14-alpha-demethylase prevents the conversion of lanosterol to ergosterol, an important component of the fungal cell wall. Inhibition of ergosterol synthesis changes the fungal cell membrane composition and integrity, alters membrane permeability and eventually leads to fungal cell lysis. Compared to other azole antifungals, posaconazole is a significantly more potent inhibitor of sterol 14-alpha demethylase. Posaconazole is the most advanced candidate for the treatment of Chagas disease. Posaconazole has entered in a phase II clinical trial in the treatment of mycoses. Synonyms: SCH56592 hydrate; SCH-56592 hydrate; SCH 56592 hydrate. Grades: >98%. CAS No. 1198769-38-8. Molecular formula: C37H44F2N8O5. Mole weight: 718.79. | |
Talaromycesone A Quick inquiry Where to buy Suppliers range | Talaromycesone A is a fungal metabolite originally isolated from Talaromyces. It is active against S. epidermidis and methicillin-resistant S. aureus (MRSA) bacteria (IC50s = 3.70 and 5.48 μM, respectively). Talaromycesone A inhibits acetylcholinesterase (AChE) in a cell-free assay (IC50 = 7.49 μM for the human enzyme). Synonyms: Talaromycesone A; 1658474-60-2; (8S,8aS,15aR,15bR,16S)-16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-7H-8,15b-methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e']bis[2]benzopyran-3,7,12-trione; AKOS040756377. Grades: >95% by HPLC. CAS No. 1658474-60-2. Molecular formula: C29H24O11. Mole weight: 548.49. | |
Tavaborole Quick inquiry Where to buy Suppliers range | Tavaborole (AN2690) is a potent antifungal that targets the post-transfer editing site of leucyl-tRNA synthetase (LeuRS). Tavaborole forms a covalent adduct with the 3' adenosine of tRNA(leu) at the editing site of fungal, but not bacterial LeuRS, locking the enzyme in an inactive conformation. Tavaborole was recently approved for the treatment of onychomycosis of the toenail in adults. Uses: Antifungal agents. Synonyms: Tavaborole; AN2690; AN 2690. Grades: >98%. CAS No. 174671-46-6. Molecular formula: C7H6BFO2. Mole weight: 151.93. | |
Terbinafine, Hydrochloride (Lamisil, N- [ (2E) -6, 6-Di methyl -2-hepten-4-ynyl] -N- methyl -1-naphthalene methanamine) Quick inquiry Where to buy Suppliers range | An orally active, antimycotic allylamine related to naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Group: Biochemicals. Alternative Names: Lamisil, N- [ (2E) -6, 6-Di methyl -2-hepten-4-ynyl] -N- methyl -1-naphthalene methanamine. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |