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| Product | Description | |
|---|---|---|
| Gamma-Aminobutyric Acid Almotriptan | A metabolite of Almotriptan. Synonyms: Almotriptan Metabolite M2. Grades: > 95%. CAS No. 603137-41-3. Molecular formula: C17H25N3O4S. Mole weight: 367.47. |  |
| Gamma-Aminobutyric Acid (GABA) | Gamma-Aminobutyric Acid (GABA). |  CA, FL & NJ |
| gamma-Aminobutyric acid t-buty ester HCl | gamma-Aminobutyric acid t-buty ester HCl. Group: Biochemicals. Grades: Highly Purified. CAS No. 58640-01-0. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C8H17NO2·HCl. US Biological Life Sciences. |  Worldwide |
| GABA (Gamma-aminobutyrIc acid, γ-Aminobutyric Acid) | An important inhibitory neurotransmitter. Foods that contain γ-aminobutyric acid (GABA) can have an immediate effect of suppressing autonomic nerve activity related to blood pressure increase. Reacts with isothiocyanates to produce thioureas which have antifungal activity. Acts as a GABAA and GABAB receptor agonist. Group: Biochemicals. Alternative Names: 4-Aminobutanoic Αcid; 3-Carboxypropylamine; 4-Aminobutyric Acid; Aminalon; GABA; Gaballon; Gamarex; Gammalon; Gammalone; Gammar; Gammasol; Mielogen; Mielomade; NSC 27418; NSC 32044; NSC 45460; NSC 51295; Oryza GABA Extract HC 90; Pharma-GABA 20S; Pharmagaba; Pharmagaba 20; Pharmagaba 20D; Piperidic acid; Piperidinic acid; γ-Aminobutanoic acid; γ-Aminobutyric Acid. Grades: Reagent Grade. CAS No. 56-12-2. Pack Sizes: 100g, 500g, 1Kg. US Biological Life Sciences. | Worldwide |
| 5-Aminovaleric acid | 5-Aminovaleric acid is believed to act as a methylene homologue of gamma-aminobutyric acid (GABA) and functions as a weak GABA agonist. Uses: Scientific research. Group: Natural products. CAS No. 660-88-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W015878. |  |
| Acamprosate Calcium | Acamprosate calcium is a gamma-aminobutyric acid(GABA)agonist and modulator of glutamatergic systems. It has been used in alcohol dependence treatments and may be an effective augmentation therapy in patients with treatment-resistant anxiety. It has low bioavailability, but also has an excellent tolerability and safety profile. It is unique in that it is not metabolized by the liver and is also not impacted by alcohol use, so it can be administered to patients with hepatitis or liver disease and to patients who continue drinking alcohol. It was approved for use in the therapy of alcohol dependence and abuse in the United States in 2004. Uses: Alcohol deterrents. Synonyms: Calcium 3-acetamidopropane-1-sulfonate; Calcium 3-(acetylamino)propanesulphonate; 3-(Acetylamino)-1-propanesulfonic Acid Calcium Salt; Calcium Acetylhomotaurine; Alcomed; Sobriol; Aotal calcium; Calcium N-acetylhomotaurinate. Grades: >98.0%. CAS No. 77337-73-6. Molecular formula: C10H20CaN2O8S2. Mole weight: 400.48. | |
| Aflatrem | Aflatrem is the secondary metabolite of Aspergillus flavus. It is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems at low dose. It potentiates the gamma-aminobutyric acid (GABA)-induced chloride current. It is a tremorgenic mycotoxin with acute neurotoxic effect. Synonyms: 4H-3,15a-Epoxy-1-benzoxepino[6',7':6,7]indeno[1,2-b]indol-4-one, 9-(1,1-dimethyl-2-propenyl)-2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3R,5bS,7aS,13bS,13cR,15aS)-; 9-(1, 1-Dimethyl-2-propenyl)-2, 3, 5b, 6, 7, 7aα, 8, 13, 13b, 13c, 14, 15-dodecahydro-5bβ-hydroxy-2, 2, 13bβ, 13cα-tetramethyl-4H-3β, 15aβ-epoxy-1-benzoxepino[6', 7':6, 7]indeno[1, 2-b]indol-4-one; α,α-dimethylallylpaspalinine. Grades: 98.0%. CAS No. 70553-75-2. Molecular formula: C32H39NO4. Mole weight: 501.66. | |
| Almotriptan metabolite M2 | Almotriptan metabolite M2. Group: Biochemicals. Alternative Names: 4- [ [ [ [3- [2- (Dimethylamino) ethyl] -1H-indol-5-yl] methyl] sulfonyl] amino] butanoic acid; gamma-Aminobutyric acid almotriptan; Almotriptan metabolite M2. Grades: Highly Purified. CAS No. 603137-41-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C17H25N3O4S. US Biological Life Sciences. | Worldwide |
| Aminooxyacetic Acid | Aminooxyacetic acid, often abbreviated AOA or AOAA, is a GABA transaminase (GABA-T) inhibitor (Ki = 9.16 μM) that inhibits 4-aminobutyrate aminotransferase (GABA-T) activity in vitro and in vivo, leading to less gamma-aminobutyric acid (GABA) being broken down. Subsequently, the level of GABA is increased in tissues. At concentrations high enough to fully inhibit 4-aminobutyrate aminotransferase activity, aminooxyacetic acid is indicated as a useful tool to study regional GABA turnover in rats. AOAA is also an inhibitor of pyridoxal phosphate (PLP)-dependent enzymes, which serve as an inhibitor by attacking the Schiff base linkage between PLP and the enzyme, forming oxime type complexes. Uses: Gaba agents. Synonyms: Aminooxyacetate; AOAA; 2-Aminooxyacetic acid; U 7524; U7524; U-7524. Grades: ≥95%. CAS No. 645-88-5. Molecular formula: C2H5NO3. Mole weight: 91.07. | |
| Bretazenil | Bretazenil (Ro 16-6028) is a partial agonist at the gamma-aminobutyric acid A (GABA A ) receptor-linked benzodiazepine site. Bretazenil is potent benzodiazepine examined, exhibiting an IC 50 (concentration at which half-maximal inhibition of specific [35S]TBPS binding occurs) of 6.1 nM. Bretazenil shows an EC 50 of 10 nM for recombinant α1β1γ2. Anticonvulsant effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 16-6028. CAS No. 84379-13-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105056. | |
| Divalproex sodium | Divalproex Sodium, consisting of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form, is a HDAC inhibitor used in the treatment of epilepsy. It acts via binding to and inhibiting gamma-aminobutyric acid (GABA) transaminase. Uses: The treatment of epilepsy. Synonyms: NSC 694279; NSC-694279; NSC694279; EP 475; EP475; EP-475; Valproate semisodium; Depakote; Epival; Depakote ER. Grades: >98%. CAS No. 76584-70-8. Molecular formula: C16H31NaO4. Mole weight: 310.41. | |
| Gabapentin-d4 hydrochloride | A labeled anticonvulsant and analgesic. Used to treat seizures, neuropathic pain, and restless leg syndrome. Inhibits the neurotransmitter gamma-Aminobutyric Acid. Gabapentin is structurally related to gamma-Aminobutyric Acid (GABA) and designed to cross the blood brain barrier. Group: 2h labeled compounds. Alternative Names: Neurontin-d4. CAS No. 1432061-73-8. Molecular formula: C9H13D4NO2. HCl. Mole weight: 175.26. Appearance: White solid. Catalog: ACM1432061738. |  |
| Indole-5-carboxylic acid, 98% | Indole-5-carboxylic acid, 98% is an oxytocin that interacts with serotonin receptors and gamma-aminobutyric acid (GABA) receptors. It has also been reported to interact with various enzymes such as cyclooxygenase-2 (COX-2) and 5-hydroxytryptamine (5-HT) receptors. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1670-81-1. Pack Sizes: 5 g. Product ID: HY-59302. | |
| L-Cycloserine | L-Cycloserine ((S)-4-Amino-3-isoxazolidone) irreversibly inhibits GABA pyridoxal 5'-phosphate-dependent aminitransferase in E. coli, as well in the brains of various animals in a time-dependent manner, results in increased levels of gamma-aminobutyric acid (GABA), which is an inhibitory neurotransmitter in vivo. Group: Inhibitors. Alternative Names: (l)-3-isoxazolidinon;(s)-3-isoxazolidinon;H-CYCLOSERINE;L-CYCLOSERINE;L-4-AMINO-3-ISOOXAZOLIDINONE;L-4-AMINO-3-ISOXALOLIDINONE;L-4-AMINO-3-ISOXAZOLIDINONE;S(-)-4-AMINO-3-ISOXAZOLIDINONE. CAS No. 339-72-0. Molecular formula: C3H6N2O2. Mole weight: 102.09. Appearance: Solid. Purity: 0.9941. Canonical SMILES: O=C1NOC[C@@H]1N. Density: 1.278. Catalog: ACM339720. | |
| L-Cycloserine | L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase ( GABA-t ) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-Cycloserine; (S)-4-Amino-3-isoxazolidone. CAS No. 339-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1122. | |
| Oxiracetam | Oxiracetam is a cyclic derivative of gamma-aminobutyric acid (GABA) that is used as a nootropic drug to improve memory and learning. Uses: Nootropic drug. Synonyms: 4-Hydroxy-2-oxopyrrolidine-N-acetamide; Hydroxypiracetam; Neuromet; ISF 2522; (+-)-Oxiracetam. Grades: >98%. CAS No. 62613-82-5. Molecular formula: C6H10N2O3. Mole weight: 158.16. | |
| Penitrem A | Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium , acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 12627-35-9. Pack Sizes: 5 mg. Product ID: HY-N6776. | |
| Piperazine citrate | Piperazine (1,4-Diazacyclohexane) citrate is a gamma-aminobutyric acid (GABA) agonist [1]. Piperazine citrate is a vital building block and is an essential core in numerous marketed agents with diverse pharmacological activities [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1,4-Diazacyclohexane citrate. CAS No. 144-29-6. Pack Sizes: 500 mg. Product ID: HY-17599. | |
| Piracetam | Piracetam (UCB-6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UCB-6215. CAS No. 7491-74-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0585. | |
| Progabide | Progabide is a gamma-aminobutyric acid (GABA) antagonist. It has agonistic activity for both the GABAA and GABAB receptors. It has antiepileptic activity and is commonly used in the treatment of epilepsy. It also has been used for many diseases, including schizophrenia, Parkinson's disease, clinical depression and anxiety disorder with varying success. Uses: Progabide has antiepileptic activity and is commonly used in the treatment of epilepsy. it also has been used for many diseases, including schizophrenia, parkinson's disease, clinical depression and anxiety disorder with varying success. Synonyms: Progabide; Halogabide; Gabrene; Gabren; Progabida; Progabidum; progabide; SL 76002; SL76002; SL-76002; DB00837; DB 00837; DB-00837; LS-45438; LS 45438; LS45438; 4-[[ (4-Chlorophenyl) (5-fluoro-2-hydroxyphenyl) methylene]amino]butanamide; Gabren; Gabrene; Halogabide; SL76-002; SL76002; (E) -4- ( (4-chlorophenyl) (5-fluoro-2-hydroxyphenyl) methyleneamino) butanamide; 4-[[ (Z) - (4-Chlorophenyl) - (3-fluoro-6-oxo-1-cyclohexa-2, 4-dienyli. Grades: 95%. CAS No. 62666-20-0. Molecular formula: C17H16ClFN2O2. Mole weight: 334.77. | |
| Progabide | Progabide is a gamma-aminobutyric acid (GABA) antagonist with antiepileptic activity. Group: Biochemicals. Alternative Names: 4- [ [ (4-Chlorophenyl) (5-fluoro-2-hydroxyphenyl) methylene] amino] butanamide; Gabren; Gabrene; Halogabide; SL 76-002; SL 76002. Grades: Highly Purified. CAS No. 62666-20-0. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Progabide | Progabide is a gamma-aminobutyric acid receptor ( GABA ) agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SL 76002. CAS No. 62666-20-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0173. | |
| (S)-homo-β-alanine | (S)-Homo-β-alanine, an amino acid occurring naturally, acts as an intermediary in thymine metabolism. Its potential to regulate oxidative stress and inflammation marks it as a prospective treatment for cardiovascular disease and hypertension. Also, research suggests its involvement in the synthesis of neurotransmitter gamma-aminobutyric acid (GABA) in the brain. Synonyms: (S)-beta-homoalanine. Grades: 95%. CAS No. 3775-72-2. Molecular formula: C4H9NO2. Mole weight: 103.11. | |
| Thiocolchicoside | Potent competitive gamma-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist. Weak nicotinic acetylcholine receptor agonist. Muscle relaxant. Anti-inflammatory. Has analgesic properties. Shows strong epileptogenic and convulsant activity. Anticancer compound through inhibition of NF-kappaB and NF-kappaB-regulated gene products. Apoptosis inducer.Suppressed osteoclastogenesis induced by RANKL and tumor cells via the NF-kappaB signaling pathway. Therapeutic option for the management of bone metastatic disease. Group: Biochemicals. Alternative Names: BRN 0072205, NSC 147755, Coltramyl, 10-thio-Colchicoside, 2-Demethoxy-2-glucosidoxythiocolchic ine. Grades: Highly Purified. CAS No. 602-41-5. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C27H33NO10S. US Biological Life Sciences. | Worldwide |
| Tiagabine | Tiagabine is a selective gamma-aminobutyric acid (GABA) reuptake inhibitor. Synonyms: NO328; NO 328; NO-328. Grades: >98%. CAS No. 115103-54-3. Molecular formula: C20H25NO2S2. Mole weight: 375.55. | |
| Tiagabine Impurity 1 | An impurity of Tiagabine which is a selective gamma-aminobutyric acid (GABA) reuptake inhibitor. Grades: > 95%. Molecular formula: C14H16OS2. Mole weight: 264.41. | |
| Tiagabine Impurity 6 | An impurity of Tiagabine which is a selective gamma-aminobutyric acid (GABA) reuptake inhibitor. Synonyms: Desmethyltiagabine; Tiagabine impurity 6; TVX38N3FFG; UNII-TVX38N3FFG; Desmethyl tiagabine [USP]; 748741-38-0; (3R)-1-(4-(3-Methyl-2-thienyl)-4-(2-thienyl)-3-buten-1-yl)-3-piperidinecarboxylic acid; 3-Piperidinecarboxylic acid, 1-(4-(3-methyl-2-thienyl)-4-(2-thienyl)-3-buten-1-yl)-, (3R)-; (R,ZE)-1-(4-(3-Methylthiophen-2-yl)-4-(thiophen-2-yl)but-3-en-1-yl)piperidine-3-carboxylic acid; DESMETHYL TIAGABINE [USP IMPURITY]. Grades: > 95%. Molecular formula: C19H23NO2S2. Mole weight: 361.53. | |
| U-93631 | U 93631 is a ligand at the picrotoxin site of GABA(A) receptors, allosterically antagonizing GABA-induced Cl- currents. U-93631 causes rapid decay of gamma-aminobutyric acid-induced chloride currents in recombinant rat gamma-aminobutyric acid type A receptors. Synonyms: 4,5-Dihydro-4,4-dimethyl-imidazo[1,5-a]quinoxaline-3-carboxylic acid 1,1-dimethylethyl ester; U93631, U-93631, U 93631. CAS No. 152273-12-6. Molecular formula: C17H21N3O2. Mole weight: 299.37. | |
| Vigabatrin | Vigabatrin is an analogue of gamma-aminobutyric acid(GABA) and is an irreversible inhibitor of 4-aminobutyrate transaminase. It is used in combination with other agents as therapy of refractory complex partial seizures and as monotherapy for infantile spasms. It is an antiepileptic drug that inhibits the breakdown of GABA by acting as a suicide inhibitor of GABA transaminase (GABA-T). It increases brain concentrations of GABA, an inhibitory neurotransmitter in the CNS, by irreversibly inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. It may also work by suppressing repetitive neuronal firing through inhibition of voltage-sensitive sodium channels. It is a racemic compound, and its [S]-enantiomer is pharmacologically active. It has been listed. Uses: Vigabatrin is used in combination with other agents as therapy of refractory complex partial seizures and as monotherapy for infantile spasms. it is an antiepileptic drug. Synonyms: γ-Vinyl-GABA; 4-Amino-5-hexenoic Acid; (±)-4-Amino-5-hexenoic Acid; Sabril; Vigabatrine; 4-Aminohexenoic acid; rac-Vigabatrin; (±)-Vigabatrin; (±)-4-Aminohexenoic acid. Grades: ≥98%. CAS No. 68506-86-5. Molecular formula: C6H11NO2. Mole weight: 129.16. | |
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