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Ghrelin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ghrelin;Ghrelin(human) acetate. Product Category: Heterocyclic Organic Compound. CAS No. 304853-26-7. Molecular formula: C149H249N47O42. Mole weight: 3370.86. Product ID: ACM304853267. Alfa Chemistry ISO 9001:2015 Certified.
Ghrelin (human)
Ghrelin (human) is an endogenous agonist peptide for the ghrelin receptor (GHS-R1a). Synonyms: Gly-Ser-Ser(octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg. CAS No. 258279-04-8. Molecular formula: C149H249N47O42. Mole weight: 3370.90.
Ghrelin(mouse,rat)
Ghrelin(mouse,rat). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ghrelin (mouse, rat);Ghrelin (rat). Product Category: Heterocyclic Organic Compound. CAS No. 258338-12-4. Molecular formula: C147H245N45O42. Mole weight: 3314.79. Purity: >95%. Product ID: ACM258338124. Alfa Chemistry ISO 9001:2015 Certified.
Ghrelin Receptor Antagonist, JMV 2959
A 1, 2, 4-triazole derived compound that acts as a potent ghrelin receptor (GHS-R1a) antagonist (IC50 = 32nM in a binding assay, dissociation constant Kb = 19nM). Shown to reduce hexarelin-induced food intake [hexarelin (80ug/kg, cumulative food intake (g of food/100g of body weight) at 6h by acute administration (sc) of JMV 2959 (160ug/kg)] in rats without affecting the basal food intake. Also suppresses ghrelin and fasting-induced food intake at the level of the central nervous system. Reported to suppress genes up-regulated by ghrelin. Does not affect intracellular Ca2+ mobilization. Group: Biochemicals. Alternative Names: (R)-N-(2-(1H-indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl)-2-aminoacetamide Hydrochloride, GHSR1a Antagonist, GH Secretagogue Receptor Antagonist, JMV2959, Growth Hormone Secretagogue Receptor Antagonist. Grades: Highly Purified. CAS No. 925238-89-7. Pack Sizes: 10mg. Molecular Formula: C??H??N?O, Molecular Weight: 254.29. US Biological Life Sciences.
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Ghrelin receptor full agonist-2
Ghrelin receptor full agonist-2 is a highly potent Ghrelin receptor full agonist. Synonyms: 5-(2-chlorophenyl)-N-((3R,4S)-1-(phenylsulfonyl)-4-(((S)-piperidin-3-yl)carbamoyl)pyrrolidin-3-yl)isoxazole-3-carboxamide. CAS No. 2602452-73-1. Molecular formula: C26H28ClN5O5S. Mole weight: 558.05.
Des-acyl ghrelin (rat)
Des-acyl ghrelin (rat) decreases food intake and gastroduodenal motility in conscious rats. Synonyms: Gly-Ser-Ser-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg. CAS No. 307950-60-3. Molecular formula: C139H231N45O41. Mole weight: 3188.67.
[Des-octanoyl]-Ghrelin (human) is a major circulating form of ghrelin. It inhibits cell proliferation in breast and prostate cancer cell lines. Synonyms: Gly-Ser-Ser-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg. CAS No. 313951-59-6. Molecular formula: C141H235N47O41. Mole weight: 3244.70.
10-Gingerol
10-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with anti-inflammatory and antioxidant activity. lt effectively inhibited the growth of these oral pathogens. lt inhibited exogenous ghrelin deacylation. lt induces [Ca2+]i rise by causing Ca2+ release from the endoplasmic reticulum and Ca2+ influx from non-L-type Ca2+ channels in SW480 cancer cells. It has anti-neuroinflammatory capacity. Synonyms: (+)-(S)-[10]-Gingerol; (S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone; (5S)-1-(3-Methoxy-4-hydroxyphenyl)-5-hydroxytetradecane-3-one. Grade: >98%. CAS No. 23513-15-7. Molecular formula: C21H34O4. Mole weight: 350.49.
1,2,4-Triazole
1,2,4-Triazole is present in a large variety of fungicides as C14-demethylase-inhibitors. In addition they are used in synthetic chemical reactions such as the design and preparation of ghrelin receptor ligand antagonists, like JMV 2959. Group: Biochemicals. Alternative Names: 1H-1,2,4-Triazole; s-Triazole; 3,4-Diazapyrrole; 4H-1,2,4-Triazole; NSC 8312. Grades: Highly Purified. CAS No. 288-88-0. Pack Sizes: 50g. US Biological Life Sciences.
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1,2,4-Triazole-1,2,4-15N3
1,2,4-Triazole-1,2,4-15N3 is the labeled analog of 1,2,4-Triazole (T767410), which is present in a large variety of fungicides as C14-demethylase-inhibitors. In addition they are used in synthetic chemical reactions such as the design and preparation of ghrelin receptor ligand antagonists, like JMV 2959. Group: Biochemicals. Grades: Highly Purified. CAS No. 1173023-70-5. Pack Sizes: 1mg, 10mg. Molecular Formula: C2H315N3, Molecular Weight: 72.05. US Biological Life Sciences.
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13Z,16Z-Docosadienoic acid
13Z,16Z-Docosadienoic acid is a natural ω-6 polyunsaturated fatty acid (PUFA). It is an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells. Synonyms: cis-13,16-Docosadienoic acid; (13Z,16Z)-docosa-13,16-dienoic acid. Grade: ≥98%. CAS No. 17735-98-7. Molecular formula: C22H40O2. Mole weight: 336.6.
1H-1,2,4-Triazole-3,5-13C2
1H-1,2,4-Triazole-3,5-13C2 is the labeled analog of 1,2,4-Triazole (T767410), which is present in a large variety of fungicides as C14-demethylase-inhibitors. In addition they are used in synthetic chemical reactions such as the design and preparation of ghrelin receptor ligand antagonists, like JMV 2959. Group: Biochemicals. Grades: Highly Purified. CAS No. 1773496-71-1. Pack Sizes: 5mg, 50mg. Molecular Formula: 13C2H3N3, Molecular Weight: 71.05. US Biological Life Sciences.
Worldwide
1H-1,2,4-Triazole-3,5-13C2-1,2,4-15N3
1H-1,2,4-Triazole-3,5-13C2-1,2,4-15N3 is labelled 1,2,4-Triazole (T767410) which is present in a large variety of fungicides as C14-demethylase-inhibitors. In addition they are used in synthetic chemical reactions such as the design and preparation of ghrelin receptor ligand antagonists, like JMV 2959. Group: Biochemicals. Grades: Highly Purified. CAS No. 1261170-82-4. Pack Sizes: 1mg, 10mg. Molecular Formula: 13C2H315N3, Molecular Weight: 74.03. US Biological Life Sciences.
Worldwide
Anamorelin
Anamorelin, also known as RC-1291 or ONO-7643, is the orally bioavailable, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Synonyms: RC 1291; RC-1291; RC1291; ONO 7643; ONO-7643; ONO7643. CAS No. 249921-19-5. Molecular formula: C31H42N6O3. Mole weight: 546.7.
Anamorelin
Anamorelin (RC-1291) is a potent ghrelin receptor agonist with EC 50 value of 0.74 nM in the FLIPR assay. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RC-1291; ONO-7643. CAS No. 249921-19-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14734.
Anamorelin Dihydrochloride
Anamorelin is a novel non-peptidic ghrelin mimetic and growth hormone secratogogue. Group: Biochemicals. Grades: Highly Purified. CAS No. 1469995-93-4. Pack Sizes: 10mg, 25mg. Molecular Formula: C31H44Cl2N6O3. US Biological Life Sciences.
Worldwide
Anamorelin Fumarate
Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite. Synonyms: RC-1291 Fumarate; ONO-7643 Fumarate; RC1291 Fumarate; ONO7643 Fumarate; RC 1291 Fumarate; ONO 7643 Fumarate. Grade: >98%. CAS No. 339539-92-3. Molecular formula: C35H46N6O7. Mole weight: 662.78.
Anamorelin HCl
Anamorelin, also known as RC-1291 or ONO-7643, is the orally bioavailable, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Uses: For research used only. Synonyms: RC 1291; RC1291; RC-1291; RC 1291 HCl; ONO-7643; ONO7643; ONO 7643; Anamorelin hydrochloride. Grade: 98%. CAS No. 861998-00-7. Molecular formula: C31H43ClN6O3. Mole weight: 583.174.
Anamorelin hydrochloride
Anamorelin (RC-1291) hydrochloride is a potent ghrelin receptor agonist with EC 50 value of 0.74 nM in the FLIPR assay. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RC-1291 hydrochloride; ONO-7643 hydrochloride. CAS No. 861998-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14734A.
AZ-GHS-22
AZ-GHS-22 is an orally-available Ghrelin receptor (GHS-R1a) inverse agonist (IC50 = 0.77 nM) with very low CNS exposure. Synonyms: AZ-GHS-22; AZ GHS-22; AZ-GHS 22; AZ GHS 22; AZGHS22; 2-chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide. Grade: 98%. CAS No. 1143020-91-0. Molecular formula: C27H33ClN6O5S2. Mole weight: 621.17.
Capromorelin tartrate
Capromorelin, also known as CP-424,391, is a growth hormone secretagogue and ghrelin mimetic ( hGHS-R1a K(I)=7 nM, rat pituicyte EC(50)=3 nM). Initial studies have shown the drug to directly raise insulin growth factor 1 (IGF-1) and growth hormone levels. Capromorelin showed enhanced intestinal absorption in rodent models and exhibited superior pharmacokinetic properties, including high bioavailabilities in two animal species [F(rat)=65%, F(dog)=44%]. This short-duration GHS was orally active in canine models and was selected as a development candidate for the treatment of musculoskeletal frailty in elderly adults. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CP-424,391; CP 424,391; CP424,391; CP-424391; CP 424391; CP424391; CP-424,391-18; Capromorelin tartrate. Product Category: Others. Appearance: Solid powder. CAS No. 193273-69-7. Molecular formula: C32H41N5O10. Mole weight: 655.71. Purity: >98%. IUPACName: 2-amino-N-((R)-1-((R)-3a-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)-3-(benzyloxy)-1-oxopropan-2-yl)-2-methylpropanamide (2R,3R)-2,3-dihydroxysuccinate. Canonical SMILES: CC(C)(N)C(N[C@@H](C(N(C[C@]12CC3=CC=CC=C3)CCC1=NN(C)C2=O)=O)COCC4=CC=CC=C4)=O.O[C@H]([C@H](C(O)=O)O)C(O)=O. Product ID: ACM193273697. Alfa Chemistry ISO 9001:2015 Certified.
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P is a broad spectrum neuropeptide inverse agonist and antagonist. It acts as a full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM) and antagonist at tachykinin, bradykinin, CCK and bombesin receptors. It induces apoptosis and inhibits cancer cell growth in vitro. Synonyms: 1-Arg-5-Phe-7,9-Trp-11-Leu-substance P; D-Arg(10)-D-Phe(5)-D-Trp(7,9)-Leu(11)-SP; substance P, phenylalanyl(5)-tryptophyl(7,9)-leucine(11)-. CAS No. 96736-12-8. Molecular formula: C79H109N19O12. Mole weight: 1516.85.
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate is a broad-spectrum neuropeptide inverse agonist and antagonist. It acts as a full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM) and antagonist at tachykinin, bradykinin, CCK, and bombesin receptors. It induces apoptosis and inhibits cancer cell growth in vitro. Synonyms: H-D-Arg-Pro-Lys-Pro-D-Phe-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2.CH3CO2H; D-arginyl-L-prolyl-L-lysyl-L-prolyl-D-phenylalanyl-L-glutaminyl-D-tryptophyl-L-phenylalanyl-D-tryptophyl-L-leucyl-L-leucinamide acetic acid; [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P acetate. Grade: ≥95%. CAS No. 2918771-49-8. Molecular formula: C81H113N19O14. Mole weight: 1576.91.
EM574
Shows strong gastrointestinal motor stimulating (GMS) activity. Motilin receptor agonist. Stimulates smooth muscle cell contraction. Stimulates cholinergic neurons in a non-vagal pathway. Enhances gastrointestinal contractile activity and accelerates gastric emptying. Shows orexigenic activity with affinity for the growth-hormone secretagogue receptor (GHS-R, ghrelin receptor). Group: Biochemicals. Grades: Highly Purified. CAS No. 110480-13-2. Pack Sizes: 250ug, 1mg. Molecular Formula: C39H69NO12. US Biological Life Sciences.
Worldwide
Fmoc-Thr[GalNAc(Ac)3-α-D]-OH
AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight. Uses: Scientific research. Group: Peptides. Alternative Names: Fmoc-Thr(Ac3AcNH-α-Gal)-OH. CAS No. 116783-35-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-P0232.
GSK894490A
GSK894490A is a non-peptide ghrelin receptor agonist. It crosses the blood/brain barrier and elicit pro-cognitive effects in recognition and spatial learning and memory tests. It may be used as a potential drug target for therapeutic approaches to treat diseases affecting cognition. Uses: Gsk894490a may be used as a potential drug target for therapeutic approaches to treat diseases affecting cognition. Synonyms: Benzenesulfonamide, N-(5-((3R,5S)-3,5-dimethyl-1-piperazinyl)-2-methoxyphenyl)-4-(5-methyl-2-furanyl)-, hydrochloride (1:1), rel-; N-[5-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-2-methoxyphenyl]-4-(5-methylfuran-2-yl)benzenesulfonamide hydrochloride; GSK-894490A. Grade: >98 %. CAS No. 1012035-06-1. Molecular formula: C24H30ClN3O4S. Mole weight: 492.03.
GSK 962040
GSK 962040 is a selective motilin receptor agonist with pEC50 value of 7.9. It is effective as a stimulant of human and rabbit gastrointestinal motility. lt represents a new opportunity as a treatment in diabetic gastroparesis. It is discovered as a therapeutic agent for conditions associated with delayed gastric emptying. It is highly selective against motilin receptor over the human ghrelin receptor and hERG. It also has no significant activity against other receptors including 5-HT, adrenergic, dopamine, histamine and adenosine receptors. It is found to enhance the EFS-induced cholinergic contraction and cause a small muscle contraction at high concentration in rabbit isolated gastric antrum. It also induces the contraction of human-isolated stomach preparations at 10μM. It had no significant activity at a range of other receptors (including ghrelin), ion channels and enzymes in vitro. It was preferred because its initial IC50 values at CYP3A4 were significantly higher than our preferred threshold of 10 μM. It induced phasic contractions, the duration of which was dose-related. It strongly facilitated cholinergic activity in the antrum, with lower activity in fundus and small intestine only. It was developed by glaxosmithkline and has been in Cilinic Phase 2. Uses: Gsk 962040 may be used as a treatment in diabetic gastroparesis. Synonyms: GSK-962040; GSK 962040; GSK962040; Camicinal; 1-[4-(3-fluoroanilino)piperidin-1-
K-(D-1-Nal)-FwLL-NH2
K-(D-1-Nal)-FwLL-NH2 is a potent and high affinity inverse ghrelin receptor inverse agonist. Its Ki values are 31 and 4.9 nM in HEK293T and COS7 cells respectively. It blocks ghrelin receptor-mediated G13- and Gq-dependent signaling pathways. Synonyms: L-Lysyl-3-(1-naphthalenyl)-D-alanyl-L-phenylalanyl-D-tryptophyl-L-leucyl-L-leucinamide; K-(D-1-Nal)-FwLL-NH2; K (D 1 Nal) FwLL NH2. Grade: >98%. CAS No. 1394288-22-2. Molecular formula: C51H67N9O6. Mole weight: 902.13.
L-Cysteine
L-Cysteine (Cysteine) is an orally active conditionally essential amino acid with hypoglycemic effects, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H2S pathway. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans. L-Cysteine can be used as an anorectic agent [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Cysteine. CAS No. 52-90-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-Y0337.
L-Cysteine-15N
L-Cysteine- 15 N is the 15 N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 204523-09-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-Y0337S1.
L-Cysteine-d3
L-Cysteine-d3 is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 214782-32-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-Y0337S5.
L-Cysteine hydrochloride
L-Cysteine hydrochloride is an orally active conditionally essential amino acid , which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 52-89-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-Y0337A.
L-Cysteine hydrochloride hydrate
L-Cysteine hydrochloride hydrate is an orally active and essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate regulates CBS/H2S pathway, inhibits NF-κB activation and insulin and ghrelin secretion. L-Cysteine hydrochloride hydrate reduces blood sugar, vascular inflammation markers and appetite. L-Cysteine hydrochloride hydrate induces kidney damage. L-Cysteine hydrochloride hydrate can be used in the study of neurological diseases and diabetes [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Natural products. CAS No. 7048-4-6. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-W016715.
L-Cysteine (hydrochloride hydrate) (Standard)
L-Cysteine (hydrochloride hydrate) (Standard) is the analytical standard of L-Cysteine (hydrochloride hydrate). This product is intended for research and analytical applications. L-Cysteine hydrochloride hydrate is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate suppresses ghrelin and reduces appetite in rodents and humans [1]. Uses: Scientific research. Group: Natural products. CAS No. 7048-4-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W016715R.
Obestatin (human)
Obestatin is a 23 amino acid peptide hormone which is formed by cleavage of the ghrelin and obestatin prepropeptide. It can suppress food intake and reduce body weight-gain in rats. Synonyms: C16102; Obestatin. Grade: ≥95% by HPLC. CAS No. 1081110-72-6. Molecular formula: C116H176N32O33. Mole weight: 2546.86.
Obestatin (rat)
Obestatin is a 23 amino acid bioactive peptide that encoded by the ghrelin gene. It can suppress food intake and reduce body weight-gain in rats. Synonyms: H-Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Ala-Gln-Tyr-Gln-Gln-His-Gly-Arg-Ala-Leu-NH2; L-phenylalanyl-L-asparagyl-L-alanyl-L-prolyl-L-phenylalanyl-L-alpha-aspartyl-L-valyl-glycyl-L-isoleucyl-L-lysyl-L-leucyl-L-seryl-glycyl-L-alanyl-L-glutaminyl-L-tyrosyl-L-glutaminyl-L-glutaminyl-L-histidyl-glycyl-L-arginyl-L-alanyl-L-leucinamide; Obestatin (mouse, rat). Grade: ≥95% by HPLC. CAS No. 869705-22-6. Molecular formula: C114H174N34O31. Mole weight: 2516.84.
Octanoyl coenzyme A lithium salt
Octanoyl coenzyme A lithium salt acts as a acyl group carrier. This is a medium-chain fatty acid convalently linked to coenzyme A. Applications: A donor molecule for the octanylation of ghrelin and other peptides. Group: Coenzymes. Synonyms: Capryloyl coenzyme A lithium salt. CAS No. 324518-20-9. Purity: ≥95%. Mole weight: 893.73. Appearance: Powder. Form: Solid. Capryloyl coenzyme A lithium salt; Octanoyl coenzyme A lithium salt; 324518-20-9. Cat No: COEC-028.
PF-5190457
PF-5190457 (PF-05190457) is a potent and selective ghrelin receptor inverse agonist with a pKi of 8.36[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-05190457. CAS No. 1334782-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12584.
Pralmorelin
Pralmorelin is a synthetic agonist of ghrelin that can increase food intake. Synonyms: GHRP-2; KP-102; D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide; H-D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2. CAS No. 158861-67-7. Molecular formula: C45H55N9O6. Mole weight: 817.94.
Relamorelin TFA
Relamorelin (RM-131) TFA, a pentapeptide ghrelin analog, is a selective ghrelin/growth hormone secretagogue receptor (GHSR) agonist with a K i of 0.42 nM for GHS-1a receptor. Relamorelin TFA is centrally penetrant. Relamorelin TFA increases growth hormone levels and accelerates gastric emptying. Relamorelin TFA has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Peptides. Alternative Names: RM-131 TFA; BIM-28131 TFA. CAS No. 2863659-22-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19884B.
Ulimorelin
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN) agonist with an EC 50 of 29 nM and a K i of 16 nM. Ulimorelin is a prokinetic agent and causes vasorelaxation through competitive antagonist action at α1-adrenoceptors. Ulimorelin stimulates intestinal motility and is used for malnutrition [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TZP-101. CAS No. 842131-33-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-14903.
YIL781
YIL781 is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 produces a greater improvement in glucose homeostasis in rats. YIL781 inhibits the calcium response induced by ghrelin with pIC 50 values of 7.90 and 8.27, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 875258-85-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-13964.
YIL781 hydrochloride
YIL781 hydrochloride is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 hydrochloride produces a greater improvement in glucose homeostasis in rats. YIL781 hydrochloride inhibits the calcium response induced by ghrelin with pIC 50 values of 7.90 and 8.27, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1640226-17-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13964A.
YIL 781, Hydrochloride Salt
Ghrelin receptor antagonist (GHS-R1a) (Ki = 17nM). Displays no significant affinity for the motilin receptor (Ki = 6uM). Blocks the effects of ghrelin on insulin secretion both in vivo and in vitro. Improves glucose homeostasis in vivo. Group: Biochemicals. Alternative Names: 6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone. Grades: Highly Purified. CAS No. 875258-85-8. Pack Sizes: 5mg. Molecular Formula: C??H??FN?O?.HCl, Molecular Weight: 445.96. US Biological Life Sciences.
Worldwide
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