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| Product | Description | |
|---|---|---|
| Glucagon-like peptide 1 (1-37), human | Glucagon-like peptide 1 (1-37) is a pancreatic hormone synthesized by post-translational processing of proglucagon. It decreases plasma glucose level in high-fat-fed mice when administered at 25 nmol/kg. Glucagon-like peptide 1 (1-37) exhibits no effect on food intake in rats and does not enhance pancreatic insulin secretion. However it induces insulin expression in intestinal epithelial cells, which can restore glucose homeostasis when implanted into diabetic mice. Synonyms: HuGLP-1; GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat); Preproglucagon (92-128) (human, bovine, guinea pig, mouse, rat); H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH; L-histidyl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-histidyl-L-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl-glycyl-L-arginyl-glycine. Grade: ≥95%. CAS No. 87805-34-3. Molecular formula: C186H275N51O59. Mole weight: 4169.48. |  |
| Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human | Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human is an C-terminal-labelled biotinylated GLP-1 (7-36) amide. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2535. |  |
| Glucagon-Like Peptide 1 Receptor Agonist | A nonpeptidic quinoxaline compound that acts as a GLP-1R agonist and an allosteric modulator of GLP-1 binding. Shown to induce GLP-1R-mediated cAMP production in BHK plasma membrane preparations (EC50=101nM) and potentiate glucose-dependent insulin release in pancreatic islets derived from wild-type, but not GLP-1R -/-, mice. Unlike GLP-1, its biological activity is not inhibited by orthosteric antagonists such as Exendin. Group: Biochemicals. Alternative Names: 6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-, 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline (DMB); Compound 2; GLP-1R Agonist. Grades: Highly Purified. CAS No. 281209-71-0. Pack Sizes: 5mg. Molecular Formula: C??H??Cl?N?O?S, Molecular Weight: 348.3. US Biological Life Sciences. |  Worldwide |
| Glucagon-Like Peptide 1 Receptor Agonist - CAS 281209-71-0 | The Glucagon-Like Peptide 1 Receptor Agonist, also referenced under CAS 281209-71-0, controls the biological activity of Glucagon-Like Peptide 1 Receptor. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy. |  |
| Glucagon-Like Peptide 1 Receptor Agonist II (4- (3- (benzyloxy) phenyl) -2- (ethylsulfinyl) -6- (trifluoromethyl) pyrimidine, Glucagon-Like Peptide 1 Receptor Agonist II, Compound B) | A pyrimidine small molecule that acts as a GLP-1 allosteric agonist that induces cAMP signaling in HEK293 cells expressing the GLP-1 receptor with EC50 = 0.66uM and 99% efficacy (similar data with rat GLP-1 receptor), does not compete with radiolabelled GLP-1 in receptor binding assays, and is not active in cells expressing the GLP-2, GIP, PTH, or glucagon receptors. In rodent islets, insulin secretion increases in a dose-dependent and glucose-dependent manner, either alone or in an additive fashion when combined with the endogenous GLP-1 peptide. In vivo, this molecule exhibits insulinotropic effects when dosed at 10mg/kg in SD rats undergoing an IVGTT and a hyperglycemic clamp. It is also shown to increase insulin secretion in perifusion assays involving normal and diabetic human islets ex vivo, at concentrations between 1 and 10uM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) | 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2; L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-argininamide; 7-36-Glucagon-like peptide 1 (Octodon degus), 8-glycine-36-L-argininamide-; Albiglutide; [Gly8,Arg36]-GLP 1 (7-36) amide (Octodon degus). Grade: ≥95%. CAS No. 224638-84-0. Molecular formula: C148H224N40O45. Mole weight: 3283.61. | |
| 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) TFA | 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) TFA is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2.TFA; L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-argininamide trifluoroacetic acid; 7-36-Glucagon-like peptide 1 (Octodon degus), 8-glycine-36-L-argininamide-, trifluoroacetate; Albiglutide TFA; [Gly8,Arg36]-GLP 1 (7-36) amide (Octodon degus) TFA. Grade: ≥95%. Molecular formula: C150H225F3N40O47. Mole weight: 3397.63. | |
| 1-((1S,2S)-1-Cyano-2-methylcyclopropyl)-5-((4S)-2,2-dimethyloxan-4-yl)-N-methyl-N-phenylindole-2-carboxamide | An intermediate of Orforglipron, which is a novel, oral glucagon-like peptide-1 (GLP-1) receptor agonist being developed for the treatment of type 2 diabetes and obesity. Synonyms: 1H-Indole-2-carboxamide, 1-[(1S,2S)-1-cyano-2-methylcyclopropyl]-N-methyl-N-phenyl-5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-; 1-[(1S,2S)-1-Cyano-2-methylcyclopropyl]-N-methyl-N-phenyl-5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-1H-indole-2-carboxamide; 1-((1S,2S)-1-Cyano-2-methylcyclopropyl)-5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide; Orforglipron Impurity 20. Grade: ≥95%. CAS No. 2212021-81-1. Molecular formula: C28H31N3O2. Mole weight: 441.56. | |
| 5-((4S)-2,2-Dimethyloxan-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide | An intermediate of Orforglipron, which is a novel, oral glucagon-like peptide-1 (GLP-1) receptor agonist being developed for the treatment of type 2 diabetes and obesity. Synonyms: N-Methyl-N-phenyl-5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-1H-indole-2-carboxamide; (S)-5-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide; Orforglipron Impurity 9. Grade: ≥95%. CAS No. 2212021-79-7. Molecular formula: C23H26N2O2. Mole weight: 362.46. | |
| 5-((S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl)-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-1H-indole-2-carboxylic acid | An intermediate of Orforglipron, which is a novel, oral glucagon-like peptide-1 (GLP-1) receptor agonist being developed for the treatment of type 2 diabetes and obesity. Synonyms: 1-[(1S,2S)-1-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)-2-methylcyclopropyl]-5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-1H-indole-2-carboxylic acid; 5-((4S)-2,2-Dimethyloxan-4-yl)-1-[(1S,2S)-2-methyl-1-(5-oxo-4H-1,2,4-oxadiazol-3-yl)cyclopropyl]indole-2-carboxylic acid; 1-((1S,2S)-1-Cyano-2-methylcyclopropyl)-5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide. Grade: ≥95%. CAS No. 2212021-83-3. Molecular formula: C22H25N3O5. Mole weight: 411.46. | |
| Aib18, Exendin-4 | Exendin-4 (Exenatide), an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Aib-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C189H291N51O61S. Mole weight: 4285.97. | |
| Aib2, Exendin-4 | Exendin-4 (Exenatide), an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Synonyms: His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C186H286N50O60S. Mole weight: 4214.89. | |
| (+Ala2)-Liraglutide | An impurity of Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used primarily to treat type 2 diabetes (T2D) and obesity. Synonyms: His-Ala-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(palm-gama-Glu)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly; L-Histidyl-L-alanyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; HAAEGTFTSDVSSYLEGQAA-Lys(Palm-γ-Glu)-EFIAWLVRGRG; [+Ala2]-Liraglutide; [+Ala]2-Liraglutide. Grade: ≥95%. Molecular formula: C175H270N44O52. Mole weight: 3822.34. | |
| AR 231453 | AR231453 is a potent and selective small molecule agonist of GPR119 that enhances glucose-dependent insulin secretion and glucagon-like peptide 1 (GLP-1) release. It is Antidiabetic agent. Synonyms: AR231453; AR-231453; AR 231453; AR-231,453; AR231,453; AR231,453. Grade: >98%. CAS No. 733750-99-7. Molecular formula: C21H24FN7O5S. Mole weight: 505.52. | |
| Arachidonyl serotonin | Arachidonyl serotonin is a dual target agent of transient receptor potential vanilloid-type I (TRPV1) antagonist and fatty acid amide hydrolase (FAAH) inhibitor, which is responsible for inactivation of anandamide and other endogenous cannabinoids. Its IC50 values are 37-40 nM and 5.6 μM for TRPV1 and FAAH respectively. It inhibits the FAAH activity isolated from mouse neuroblastoma cells with an IC50 value of 12 μM. It is a very tight binding, competitive inhibitor of FAAH. It does not inhibit cPLA2 and is essentially devoid of cannabimimetic activity. It was shown to be present in the ileum and jejunum of the gastrointestinal tract and modulate glucagon-like peptide-1 (GLP-1) secretion. It displays strong analgesic activity against both acute and chronic peripheral pain in rodents. Synonyms: AA-5HT; AA5HT; AA 5HT; N-arachidonoyl-serotonin; Arachidonoyl serotonin; N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide; AA-5HT; AA5HT; N-arachidonoyl-serotonin; N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-eicosatetraenamide; (5Z,8Z,11Z,14Z)-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)icosa-5,8,11,14-tetraenamide. CAS No. 187947-37-1. Molecular formula: C30H42N2O2. Mole weight: 462.67. | |
| BETP | BETP is an agonist of glucagon-like peptide-1 (GLP-1) receptor, with EC50s of 0.66 and 0.755 ?M for human and rat GLP-1 receptor, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1371569-69-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103546. | |
| BETP | BETP is a positive allosteric modulator and partial agonist of the glucagon-like peptide 1 (GLP-1) receptor, displaying no effect on GLP-2, GIP, PTH or glucagon receptors. BETP promotes oxyntomodulin binding to GLP-1 receptor. It potentiates oxyntomodulin-mediated GLP-1 receptor signaling in vitro and insulin secretion in vivo. Synonyms: 2-(Ethylsulfinyl)-4-[3-(phenylmethoxy)phenyl]-6-(trifluoromethyl)pyrimidine. Grade: ≥98% by HPLC. CAS No. 1371569-69-5. Molecular formula: C20H17F3N2O2S. Mole weight: 406.42. | |
| Boc5 | Boc5, a non-peptide glucagon-like peptide-1 (GLP-1R) receptor agonist. Synonyms: 1,3-Bis[[4-(Tert-Butoxy-Carbonylamino)Benzoyl]Amino]-2,4-Bis[3-Methoxy-4-(Thiophene-2-Carbonyloxy)-Phenyl]Cyclobutane-1,3-Dicarboxylic Acid. Grade: ≥98% by HPLC. CAS No. 917569-14-3. Molecular formula: C54H52N4O16S2. Mole weight: 1077.1. | |
| Bofanglutide | Bofanglutide (GZR18) is an analog of glucagon-like peptide-1 (GLP-1), which exhibits agonistic activity for GLP-1 receptor , with an EC 50 of 0.677 nM. GZR18 ameliorates type 2 diabetes [1]. Uses: Scientific research. Group: Peptides. Alternative Names: GZR18. CAS No. 2668298-70-0. Pack Sizes: 1 mg. Product ID: HY-P10269. | |
| BPI-3016 | BPI-3016 is an analogue of human glucagon-like peptide 1 (hGLP-1) that has a long effect on type 2 diabetes mellitus. In vitro, BPI-3016 exhibited an affinity to GLP receptors and promotes cAMP production. In vivo, the half-life of BPI-3016 was 95h after single dosing in pharmacokinetic studies in diabetic cynomolgus monkey models. Uses: The treatment of type 2 diabetes. Synonyms: BPI-3016; BPI 3016; BPI3016. | |
| Cotadutide | Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC 50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D) [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: MEDI0382. CAS No. 1686108-82-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2231. | |
| Cys38, Oxyntomodulin amide, (human, mouse, rat) | Oxyntomodulin is a peptide hormone that's released into the blood after eating. OXM is a dual agonist of the glucagon-like peptide-1 receptor (GLP1R) and the glucagon receptor (GCGR). Synonyms: His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-Lys-Arg-Asn-Arg-Asn-Asn-Ile-Ala-Cys-NH2. Molecular formula: C195H301N63O60S2. Mole weight: 4551.98. | |
| Cys40, Exendin-4 | Cys40-Exendin-4 is a radiolabeled peptide that can be used as a tracer in PET imaging. It's a glucagon-like peptide 1 (GLP-1) receptor agonist that can be used to image insulinomas and transplanted human islets. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-Cys-NH2. Molecular formula: C187H287N51O61S2. Mole weight: 4289.69. | |
| Cys(mPEG20K), Exendin-4 (9-39) | Cys(mPEG20K), Exendin-4 (9-39) is a potent glucagon-like peptide 1 (GLP-1) receptor antagonist Exendin-4 (9-39) conjugated with mPEG20K linker, which can be used in studies of diabetes treatment. Synonyms: Cys(mPEG20K)-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. | |
| D3-βArr | D3-βArr is a positive allosteric modulator of thyrotropin (TSH) receptor. D3-βArr does not activate Beta-Arr 1 translocation to the glucagon-like peptide 1 receptor (GLP-1R) in CHO-K1-GLP1R-Beta Arrestin 1 cells. Synonyms: NCGC00379308; D3-betaArr. CAS No. 662164-09-2. Molecular formula: C20H23N5. Mole weight: 333.4. | |
| D-Ala(18)-Semaglutide | D-Ala(18)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: [D-Ala18]-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48R,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Ala(19)-Semaglutide | D-Ala(19)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-Ala-19-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51R,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Ala(24)-Semaglutide | D-Ala(24)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-Ala-24-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24R,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| [D-ala2]-Liraglutide | [D-ala2]-Liraglutide is a derivative of Liraglutide, a long-acting analog of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Synonyms: D-ala2-Liraglutide; H-His-D-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(1)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH.palmitoyl-Glu(1)-OH. Molecular formula: C172H265N43O51. Mole weight: 3751. | |
| Danuglipron | Danuglipron is an orally small-molecule glucagon-like peptide 1 receptor (GLP-1R) agonist. Danuglipron is undergoing clinical trials for the treatment of diabetes. Synonyms: PF-06882961; PF 06882961; PF06882961. Grade: 98% by HPLC. CAS No. 2230198-02-2. Molecular formula: C31H30FN5O4. Mole weight: 555.6. | |
| Danuglipron | Danuglipron (PF-06882961) is an orally active glucagon-like peptide-1 receptor (GLP-1R) agonist. Danuglipron has the potential for type 2 diabetes research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-06882961. CAS No. 2230198-02-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125824. | |
| Danuglipron free base | Danuglipron, also known as PF-06882961 is a potent, orally bioavailable agonist of the glucagon-like peptide-1 receptor agonist (GLP-1R). WO 2019148044 (2019). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Danuglipron; PF-06882961; PF 06882961; PF06882961; Danuglipron free base. Product Category: Agonists. Appearance: Solid powder. CAS No. 2230198-02-2. Molecular formula: C31H30FN5O4. Mole weight: 555.61. Purity: >98%. IUPACName: (S)-2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl)piperidin-1-yl)methyl)-1-(oxetan-2-ylmethyl)-1H-benzo[d]imidazole-6-carboxylic acid. Canonical SMILES: OC(C1=CC=C(N=C(CN2CCC(C3=NC(OCC4=CC=C(C#N)C=C4F)=CC=C3)CC2)N5C[C@H]6OCC6)C5=C1)=O. Product ID: ACM2230198022. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Danuglipron tromethamine | PF-06882961 is a potent, orally bioavailable agonist of the glucagon-like peptide-1 receptor agonist (GLP-1R). Synonyms: PF-06882961 tromethamine; PF-06882961 Tris; Danuglipron Tris; 2-((4-(6-(4-cyano-2-fluorobenzyloxy)pyridin-2-yl)piperidin-1-yl)methyl)-1-((2S)-oxetan-2-ylmethyl)-1H-benzimidazole-6-carboxylic acid, (1:1) salt with 2-amino-2-(hydroxymethyl)propane-1,3-diol. CAS No. 2230198-03-3. Molecular formula: C35H41FN6O7. Mole weight: 676.75. | |
| Dapiglutide | Dapiglutide is a long-acting dual agonist of glucagon-like peptide-1 receptor 1R (GLP-1R)/Glucagon-like peptide-2 receptor (GLP-2R) for the study of short bowel syndrome (SBS). Synonyms: ZP7570. CAS No. 2296814-85-0. Molecular formula: C192H302N46O57. Mole weight: 4166.79. | |
| Dapiglutide | Dapiglutide (ZP7570) is a long-acting glucagon-like peptide-1 receptor 1R (GLP-1R)/Glucagon-like peptide-2 receptor (GLP-2R) dual agonist. Dapiglutide alleviates intestinal dysfunction in a mouse short bowel model and has anti-obesity effects [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: ZP7570. CAS No. 2296814-85-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3291. | |
| [D-Arg30]-Semaglutide | [D-Arg30]-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6R,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Asp(9)-Semaglutide | D-Asp(9)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: (3S,9S,12S,15S,18S,21R,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| Des-Ala2-Liraglutide | An impurity of Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used primarily to treat type 2 diabetes (T2D) and obesity. Synonyms: His-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(palm-gama-Glu)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly; HEGTFTSDVSSYLEGQAA-Lys(Palm-γ-Glu)-EFIAWLVRGRG; L-Histidyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; Des-Ala(2)-Liraglutide; H-His-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Glu-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Kyn-Leu-Val-Arg-Gly-Arg-Gly-OH; [Des-Ala2]-Liraglutide; [Des-Ala]2-Liraglutide. Grade: ≥95%. Molecular formula: C169H260N42O50. Mole weight: 3680.18. | |
| Des-Gln(17)-Semaglutide | Des-Gln(17)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C182H283N43O57. Mole weight: 3985.44. | |
| Des-Glu(3)-Semaglutide | Des-Glu(3)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: L-Histidyl-2-methylalanylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-His-Aib-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Des-Glu(9)-Semaglutide. Molecular formula: C182H284N44O56. Mole weight: 3984.53. | |
| Des-Gly(16)-Semaglutide | Des-Gly(16)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C185H288N44O58. Mole weight: 4056.51. | |
| Des-Gly(29)-Semaglutide | Des-Gly(29)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,9S,12S,15S,18S,21S,24S,27S,30S)-18-((1H-indol-3-yl)methyl)-1-amino-27-benzyl-24-((S)-sec-butyl)-32-carboxy-6-((carboxymethyl)carbamoyl)-9-(3-guanidinopropyl)-1-imino-15-isobutyl-12-isopropyl-21-methyl-8,11,14,17,20,23,26,29-octaoxo-2,7,10,13,16,19,22,25,28-nonaazadotriacontan-30-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Molecular formula: C185H288N44O58. Mole weight: 4056.51. | |
| Des-Gly(31)-Semaglutide | Des-Gly(31)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide Des Gly-10 Impurity; (3S,6S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,42S,45S,48S,51S,78S)-51-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-Indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-42-(3-amino-3-oxopropyl)-9-benzyl-36-(2-carboxyethyl)-18-(carboxymethyl)-30-(4-hydroxybenzyl)-6,12-bis((R)-1-hydroxyethyl)-15,24,27-tris(hydroxymethyl)-33-isobutyl-21-isopropyl-45,48-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,57,66,75,80-icosaoxo-59,62,68,71-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,56,65,74,79-icosaazahexanonacontane-1,78,96-tricarboxylic acid. Molecular formula: C185H288N44O58. Mole weight: 4056.59. | |
| Des-Gly4-Liraglutide | An impurity of Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used primarily to treat type 2 diabetes (T2D) and obesity. Synonyms: His-Ala-Glu-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(palm-gama-Glu)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly; HAETFTSDVSSYLEGQAA-Lys(Palm-γ-Glu)-EFIAWLVRGRG; L-Histidyl-L-alanyl-L-α-glutamyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; Des-Gly(4)-Liraglutide; H-His-Ala-Glu-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; [Des-Gly4]-Liraglutide; [Des-Gly]4-Liraglutide. Grade: ≥95%. Molecular formula: C170H262N42O50. Mole weight: 3694.21. | |
| Des-Gly(4)-Semaglutide | Des-Gly(4)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; L-Histidyl-2-methylalanyl-L-α-glutamyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; Semaglutide SZ Impurity 5; Semaglutide Des Gly-10 Impurity. Molecular formula: C185H288N44O58. Mole weight: 4056.59. | |
| Des His1, Exendin-4 | Des His1, Exendin-4 is a potent glucagon-like peptide-1 receptor (GLP-1-R) antagonist. Synonyms: Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C178H275N47O59S. Mole weight: 4049.68. | |
| Des-His(1)-Semaglutide | Des-His(1)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; 2-Methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; Semaglutide Des His-7; Semaglutide SZ Impurity 7. Molecular formula: C181H284N42O58. Mole weight: 3976.50. | |
| Des-Ser(11)-Semaglutide | Des-Ser(11)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C184H286N44O57. Mole weight: 4026.49. | |
| Des-Thr5-Liraglutide | An impurity of Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used primarily to treat type 2 diabetes (T2D) and obesity. Synonyms: His-Ala-Glu-Gly-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(palm-gama-Glu)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly; HAEGFTSDVSSYLEGQAA-Lys(Palm-γ-Glu)-EFIAWLVRGRG; L-Histidyl-L-alanyl-L-α-glutamylglycyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; [Des-Thr5]-Liraglutide; His-Ala-Glu-Gly-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys (γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Des-Thr(4)-Liraglutide; [Des-Thr]5-Liraglutide. Grade: ≥95%. Molecular formula: C168H258N42O49. Mole weight: 3650.16. | |
| Des-Thr(7)-Semaglutide | Des-Thr(7)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,42S,45S,48S,51S,78S)-51-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-Indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-42-(3-amino-3-oxopropyl)-9-benzyl-36-(2-carboxyethyl)-18-(carboxymethyl)-30-(4-hydroxybenzyl)-12-((R)-1-hydroxyethyl)-15,24,27-tris(hydroxymethyl)-33-isobutyl-21-isopropyl-45,48-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,57,66,75,80-icosaoxo-59,62,68,71-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,56,65,74,79-icosaazahexanonacontane-1,78,96-tricarboxylic acid. Molecular formula: C183H284N44O57. Mole weight: 4012.54. | |
| Des-Tyr(13)-Semaglutide | Des-Tyr(13)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,42S,45S,48S,51S,78R)-51-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-42-(3-amino-3-oxopropyl)-12-benzyl-36-(2-carboxyethyl)-21-(carboxymethyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-33-isobutyl-24-isopropyl-45,48-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,57,66,75,80-icosaoxo-59,62,68,71-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,56,65,74,79-icosaazahexanonacontane-1,78,96-tricarboxylic acid. Molecular formula: C178H282N44O57. Mole weight: 3950.39. | |
| Des-Val(10)-Semaglutide | Des-Val(10)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C182H282N44O58. Mole weight: 4014.44. | |
| D-Glu(15)-Semaglutide | D-Glu(15)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-[Glu]-15-Semaglutide. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| [D-Glu3]-Semaglutide | [D-Glu3]-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: (3R,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-His1-Liraglutide | An impurity of Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used primarily to treat type 2 diabetes (T2D) and obesity. Synonyms: D-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(palm-gama-Glu)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly; DHis-AEGTFTSDVSSYLEGQAA-Lys(Palm-γ-Glu)-EFIAWLVRGRG; D-Histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; [D-His1]-Liraglutide; [D-His]1-Liraglutide; D-His(1)-Liraglutide; Liraglutide D-His(1); D-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Grade: ≥95%. Molecular formula: C172H265N43O51. Mole weight: 3751.26. | |
| D-His(1)-Semaglutide | D-[His]-1-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 6; Semaglutide D-His-7 Impurity; D-His(7)-Semaglutide; D-[His]-1-Semaglutide; D-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-D-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-His-endo-Ala18-Liraglutide | D-His-endo-Ala18-Liraglutide is a derivative of Liraglutide, a long-acting analog of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Synonyms: H-D-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Ala-Lys(Gamma-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C175H270N44O52. Mole weight: 3822.36. | |
| Dimethyl DL-glutamate hydrochloride | Dimethyl DL-glutamate is a cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes. It also potentiates the insulinotropic potential of glyburide and glucagon-like peptide Dimethyl DL-glutamate is used as a cell-permeable form of glutamate in studies of glutamate action in β-cells. Synonyms: Glutamic acid dimethyl ester; Dimethyl 2-aminopentanedioate; Dimethyl 2-aminopentanedioate hydrochloride; H-DL-Glu(OMe)-OMe.HCl; H-DL-Glu(Ome)-Ome. Grade: ≥ 98% (HPLC). CAS No. 13515-99-6. Molecular formula: C7H13NO4·HCl. Mole weight: 211.6. | |
| Dipeptidyl peptidase IV | Dipeptidyl peptidase IV (DPP-IV) is a protease that inactivates insulin stimulating hormones such as glucagon-like peptide 1 (GLP-1) and glucose-dependent insulin-like polypeptide (GIP). Dipeptidyl peptidase IV can be used as a binding protein and ligand for various extracellular molecules. Dipeptidyl peptidase IV can be used in diabetes research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DPP-IV. CAS No. 54249-88-6. Pack Sizes: 10 mU. Product ID: HY-E70397. | |
| Di-Ser(12)-Semaglutide | Di-Ser(12)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C190H296N46O61. Mole weight: 4200.64. | |
| D-Leu(14)-Semaglutide | D-Leu(14)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-[Leu]-14-Semaglutide. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| (D-Met)14, Exendin-4 | Exendin-4 (Exenatide), an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-(D-Met)-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C184H282N50O60S. Mole weight: 4186.56. | |
| D-Phe(6)-Semaglutide | D-Phe(6)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-D-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys (AEEAc-AEEAc-γ-Glu-17-carboxy heptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; (3S,9S,12R,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Ser(11)-Semaglutide | D-Ser(11)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-[Ser]-11-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27R,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Ser(12)-Semaglutide | D-Ser(12)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-Ser-12-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27S,30R,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamo. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Ser(8)-Semaglutide | D-Ser(8)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-[Ser]-8-Semaglutide; H-His-Aib-Glu-Gly-Thr-Phe-Thr-D-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; L-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-D-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| [D-Thr5]-Liraglutide | [D-Thr5]-Liraglutide is a derivative of Liraglutide, a long-acting analog of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Synonyms: D-Thr5-Liraglutide; H-His-Ala-Glu-Gly-D-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(1)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH.palmitoyl-Glu(1)-OH. Molecular formula: C172H265N43O51. Mole weight: 3751. | |
| D-Tyr(13)-Semaglutide | D-Tyr(13)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-[Tyr]-13-Semaglutide. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| Dulaglutide | Dulaglutide (LY2189265) is a glucagon-like peptide-1 (GLP-1) receptor agonist. Dulaglutide can be uesd for the research of type 2 diabetes (T2D) [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: LY2189265. CAS No. 923950-08-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0120. | |
| D-Val(10)-Semaglutide | D-Val(10)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-[Val]10-Semaglutide; D-[Val]-10-Semaglutide; (3S,9S,12S,15S,18S,21S,24R,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-Indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic Acid. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
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