Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Anti-Glycine Receptor ?3 antibody produced in rabbit | affinity isolated antibody, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. |  |
| Anti-Glycine Receptor antibody produced in rabbit | affinity isolated antibody, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| 1-Aminocyclobutanecarboxylic acid | 1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist acting at the glycine site, NR1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 22264-50-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-30006. |  |
| 1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8 | An agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex. Group: Fluorescence/luminescence spectroscopy. | |
| 1-Aminocyclopropanecarboxylic acid | 1-Aminocyclopropanecarboxylic acid is a small molecule agonist at the glycine modulatory site of the NMDA receptor. Described to mimic the effects of glycine at the NMDAR, 1-Aminocyclopropanecarboxylic acid competitively inhibits binding of [3H]glycine and enhances the binding of [3H]MK-801 to NMDAR-coupled cation channels similarly to glycine (though with less efficacy). Uses: Neuroprotective agents. Synonyms: ACC; ACPC; NSC 98430; 1-Aminocyclopropane-1-carboxylic acid. Grade: ≥98%. CAS No. 22059-21-8. Molecular formula: C4H7NO2. Mole weight: 101.1. |  |
| 1-Decanol | 1-Decanol is a long chain alcohol that has been seen to enhance homomeric glycine receptor function. In addition, the 5HT2α receptors were inhibited by the presence of 1-decanol. This action has many psychological repercussions on an individual. Synonyms: Decyl Alcohol; 1-Hydroxydecane; Alfol 10; Antak; Capric alcohol; Caprinic Alcohol; Conol 1098; Conol 10N; Decanol; Epal 10; Kalcohl 10; Kalcohl 1098; Kalcohl 10H; Kalcol 1098; NSC 406313; Nacol 10; Nacol 10-99; Nafol 10; Nafol 10D; Nonylcarbinol; Royaltac. Grade: > 95%. CAS No. 112-30-1. Molecular formula: C10H22O. Mole weight: 158.28. | |
| 1-Decanol-[d2] | Labelled 1-Decanol. 1-Decanol is a long chain alcohol that has been seen to enhance homomeric glycine receptor function. In addition, the 5HT2α receptors were inhibited by the presence of 1-decanol. Synonyms: DECANOL-1,1-D2. Grade: >98%. CAS No. 42006-99-5. Molecular formula: C10H20D2O. Mole weight: 160.29. | |
| 2-Aminoethanesulfinic acid-[d4] | 2-Aminoethanesulfinic acid-[d4] is the labelled analogue of 2-Aminoethanesulfinic acid, which is an endogenous inhibitory amino acid for glycine receptor (GlyR). It acts as an antioxidant and a protective agent under physiological conditions. Synonyms: 2-Aminoethane-d4-sulfinic Acid; 2-Aminoethylsulfinic Acid-d4; 2-Aminoethanesulfinic acid-d4; Cystaminesulfinic acid-d4; Hypotaurine-d4. Grade: 98%; 98% atom D. CAS No. 352438-83-6. Molecular formula: C2H3D4NO2S. Mole weight: 113.17. | |
| (2S, 3S, 4S) -2-Methyl-2- (carboxycyclopropyl) glycine | (2S, 3S, 4S) -2-Methyl-2- (carboxycyclopropyl) glycine is an antagonist of group II metabotropic glutamate receptors (mGluRs). Group: Biochemicals. Grades: Highly Purified. CAS No. 157141-16-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C7H11NO4, Molecular Weight: 173.17. US Biological Life Sciences. |  Worldwide |
| 3,4-Dehydro-L-proline | 3,4-Dehydro-L-proline is used to prepare morpholinyl-4-piperidinylacetic acid derivatives as potent oral active VLA-4 antagonists. It is also a β-Proline analog used as agonists at the strychnine-sensitive glycine receptor. Synonyms: 3,4-Dehydro-L-Pro-OH; (S)-3,4-Dehydro-pyrrolidine-2-carboxylic acid; (S)-2,5-Dihydro-1H-pyrrole-2-carboxylic acid; L-3,4-Dehydroproline; (2S)-2,5-dihydro-1H-pyrrole-2-carboxylic acid; L-3-Pyrroline-2-carboxylic acid; (S)-3-Pyrroline-2-carboxylic acid. Grade: ≥ 99%. CAS No. 4043-88-3. Molecular formula: C5H7NO2. Mole weight: 113.11. | |
| 5,7-Dichlorokynurenic acid | 5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective and competitive antagonist of the glycine site on NMDA receptor with a K B of 65 nM. 5,7-Dichlorokynurenic acid, a derivative of kynurenic acid, reduced NMDA-induced neuron injury in rat cortical cell cultures [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5,7-DCKA. CAS No. 131123-76-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100834. | |
| 5,7-Dichlorokynurenic acid | 5,7-Dichlorokynurenic acid has been found to be an effective NMDA receptor glycine binding site antagonist. Uses: Excitatory amino acid antagonists. Synonyms: 5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid. Grade: ≥98% by HPLC. CAS No. 131123-76-7. Molecular formula: C10H5Cl2NO3. Mole weight: 258.06. | |
| 5,7-Dichlorokynurenic acid sodium salt | The sodium salt form of 5,7-Dichlorokynurenic acid, which is an effective antagonist at the glycine site of the NMDA receptor. Synonyms: 5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid sodium salt. Grade: ≥98% by HPLC. CAS No. 1184986-70-6. Molecular formula: C10H4Cl2NNaO3. Mole weight: 280.04. | |
| 5,7-Dichlorokynurenic Acid, Sodium Salt (5,7-Dichloro-4-hydroxyquinoline-2-c-arboxylic Acid Sodium Salt, DCKA) | A very potent, water-soluble antagonist of thenMDA receptors complex acting at the strychnine-insensitive glycine binding site (Ki = 79nM vs. [3H]-glycine). Group: Biochemicals. Grades: Highly Purified. CAS No. 1184986-70-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 7-Chlorokynurenic acid | 7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor ( IC 50 =0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a K i of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 7-CKA. CAS No. 18000-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100811. | |
| 7-Chlorokynurenic acid | 7-Chlorokynurenic acid is a water-soluble and very potent NMDA receptor antagonist acting at the strychnine-insensitive glycine binding site. It is also a potent competitive inhibitor of L-glutamate transport into synaptic vesicles. It is used in studies of schizophrenia and neuroprotection. Synonyms: 7CKA; 7-CKA; 7 CKA; 7-Chloro-4-hydroxyquinoline-2-carboxylic acid. Grade: ≥98% by HPLC. CAS No. 18000-24-3. Molecular formula: C10H6ClNO3. Mole weight: 223.62. | |
| 7-Chlorokynurenic acid sodium salt | 7-Chlorokynurenic acid sodium salt is the sodium salt of 7-Chlorokynurenic acid, which is a water-soluble and very potent NMDA receptor antagonist acting at the strychnine-insensitive glycine binding site with IC50 value of 0.56 μM. It is also a potent competitive inhibitor of L-glutamate transport into synaptic vesicles. It is used in studies of schizophrenia and neuroprotection. Synonyms: 7-Chloro-4-hydroxyquinoline-2-carboxylic acid sodium salt. Grade: ≥98% by HPLC. CAS No. 1263094-00-3. Molecular formula: C10H5ClNNaO3. Mole weight: 245.59. | |
| 7-Chlorokynurenic Acid Sodium Salt (7-Chloro-4-hydroxyquinoline-2-carbo-xylic Acid Sodium Salt) | A very potent, water-soluble antagonist of the nMDA receptors complex acting at the strychnine-insensitive glycine binding site (IC50 = 0.56uM). Also a potent inhibitor of glutamate transporter. Often used in studies of neuroprotection and schizophrenia. Group: Biochemicals. Grades: Highly Purified. CAS No. 1263094-00-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) | 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2; L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-argininamide; 7-36-Glucagon-like peptide 1 (Octodon degus), 8-glycine-36-L-argininamide-; Albiglutide; [Gly8,Arg36]-GLP 1 (7-36) amide (Octodon degus). Grade: ≥95%. CAS No. 224638-84-0. Molecular formula: C148H224N40O45. Mole weight: 3283.61. | |
| 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) TFA | 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) TFA is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2.TFA; L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-argininamide trifluoroacetic acid; 7-36-Glucagon-like peptide 1 (Octodon degus), 8-glycine-36-L-argininamide-, trifluoroacetate; Albiglutide TFA; [Gly8,Arg36]-GLP 1 (7-36) amide (Octodon degus) TFA. Grade: ≥95%. Molecular formula: C150H225F3N40O47. Mole weight: 3397.63. | |
| (Ala1)-PAR4 (1-6) (mouse) trifluoroacetate salt | (Ala1)-PAR4 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence with an alanine residue substituted for glycine at position 1/60. Synonyms: H-Ala-Tyr-Pro-Gly-Lys-Phe-OH; L-alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalanine trifluoroacetate salt. Grade: ≥95%. Molecular formula: C34H47N7O8·xCF3COOH. Mole weight: 681.78. | |
| Alvimopan-[d5] | Alvimopan-[d5] is the labelled analogue of Alvimopan. Alvimopan is a μ-opioid receptor antagonist with limited activity of μ-opioid receptor in the central nervous system. It is indicated for postoperative ileus. Synonyms: Alvimopan-d5; rac-N-[2-[[4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-(phenyl-d5)propyl]glycine; ADL 8-2698-d5; LY 246736-d5; Entereg-d5. Grade: >95%. CAS No. 1217616-62-0. Molecular formula: C25H27D5N2O4. Mole weight: 429.56. | |
| Alvimopan-[d7] | Alvimopan-[d7] is the labelled analogue of Alvimopan. Alvimopan is a μ-opioid receptor antagonist with limited activity of μ-opioid receptor in the central nervous system. It is indicated for postoperative ileus. Synonyms: Alvimopan-d7; rac-N-[2-[[4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-(phenyl)propyl]glycine-d7; ADL 8-2698-d7; LY 246736-d7; Entereg-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1261396-48-8. Molecular formula: C25H25D7N2O4. Mole weight: 431.58. | |
| ALX-5407 hydrochloride | ALX-5407 ((R)-NFPS) hydrochloride is a selective and orally active glycine transporter GlyT1 inhibitor with an IC 50 value of 3 nM. ALX-5407 hydrochloride can be used the research of N-methyl-D-aspartate-receptor function and schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-NFPS hydrochloride. CAS No. 200006-08-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-10711A. | |
| Apimostinel | Apimostinel is a selective partial agonist of an allosteric site of the glycine site of the NMDA receptor complex under investigation by Naurex. Its mechanism of action and effects are similar to those of rapastinel. But Apimostinel is 100-fold more potent by weight and, unlike rapastinel (which must be administered via intravenous injection), is orally-active. Phase II clinical trials for the treatment of Major depressive disorder is on-going. Uses: Major depressive disorder. Synonyms: NRX-1074; NRX 1074; NRX1074; AGN-241660; AGN241660; AGN 241660. Apimostinel; (2R)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-2-benzylpyrrolidine-2-carboxamide. Grade: 98%. CAS No. 1421866-48-9. Molecular formula: C25H37N5O6. Mole weight: 503.60. | |
| [Asp5,Gly9-OH]-Atosiban | An impurity of Atosiban. Atosiban is a synthetic peptide that acts as a selective oxytocin receptor antagonist, primarily used to delay preterm labor in pregnant women. Synonyms: Mpr-DTyr(Et)-Ile-Thr-Asp-Cys-Pro-Orn-Gly(Mpr1&Cys6 bridge); deamino-Cys-D-Tyr(Et)-Ile-Thr-Asp-Cys-Pro-Orn-Gly (Disulfide bridge: Cys1-Cys6); Deamino-cysteinyl-O4-ethyl-D-tyrosyl-L-isoleucyl-L-threonyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-ornithyl-glycine (1->6)-disulfide; [Asp5,Gly9]-Atosiban; Asp5,Gly9-Atosiban; Asp5 Gly9 Atosiban; Asp5,Gly9-OH-Atosiban. Grade: ≥95%. CAS No. 2014351-17-6. Molecular formula: C43H65N9O14S2. Mole weight: 996.16. | |
| Axltide | Axltide is based on mouse insulin receptor substrate 1 (amino acids 979-989). It is also a substrate for the kinases AXL, DDR2, MST1 and JAK2. Synonyms: Axl/Insulin Receptor Substrate Peptide; H-Lys-Lys-Ser-Arg-Gly-Asp-Tyr-Met-Thr-Met-Gln-Ile-Gly-OH; L-lysyl-L-lysyl-L-seryl-L-arginyl-glycyl-L-alpha-aspartyl-L-tyrosyl-L-methionyl-L-threonyl-L-methionyl-L-glutaminyl-L-isoleucyl-glycine. Grade: ≥98%. CAS No. 143364-95-8. Molecular formula: C63H107N19O20S2. Mole weight: 1514.77. | |
| BAM-22P | BAM 22P is a potent endogenous agonist peptide for sensory neuron specific receptor (SNSR) (EC50 = 13 and 16 nM for human SNSR3 and SNSR4, respectively). BAM 22P is also a potent opioid agonist (IC50 = 1.3 nM in guinea pig ileum preparation) displaying opioid- and non-opioid receptor mediated antinociceptive effects in vivo. Synonyms: Bovine adrenal medulla-22P; Bam 22P; H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl-L-valyl-glycyl-L-arginyl-L-prolyl-L-alpha-glutamyl-L-tryptophyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-arginyl-L-tyrosyl-glycine. Grade: ≥95%. CAS No. 76622-26-9. Molecular formula: C130H184N38O31S2. Mole weight: 2839.22. | |
| BAM (8-22) | BAM (8-22) is an endogenous peptide agonist for the sensory neuron specific receptor (SNSR) (EC50 = 28 and 14 nM for SNSR3 and SNSR4, respectively). It exhibits spinal analgesic effects by interacting with NMDA receptors. BAM (8-22) displays no affinity for opioid receptors compared to BAM 22. Synonyms: Bovine Adrenal Medulla Peptide (8-22); H-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH; BAM-22P (8-22); L-valyl-glycyl-L-arginyl-L-prolyl-L-alpha-glutamyl-L-tryptophyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-arginyl-L-tyrosyl-glycine; BAM-15. Grade: ≥95%. CAS No. 412961-36-5. Molecular formula: C91H127N25O23S. Mole weight: 1971.22. | |
| β-Alanine | β-Alanine is a naturally occurring beta amino acid, formed in vivo by the degradation of dihydrouracil and carnosine. It is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. It is a non-specific endogenous agonist at the inhibitory glycine receptor and more selective than taurine. It is the rate-limiting precursor of carnosine, as a result supplementation with β-alanine increases the concentration of carnosine in muscles. It has been used as a ligand for the orphan MAS-related receptor. It is also applied in culture media used for certain strains of yeast to test for β-alanine auxotrophy. It also distinguishes between GABA transporters. Nutritional supplement in health care products. Uses: Β-alanine is a non-essential amino acid that is critical for the creation of new drugs. it is an essential component in many pharmacological research and application fields due to its distinct qualities and possible therapeutic advantages. the synthesis of carnosine, a dipeptide made of β-alanine and histidine, is one of the primary functions of β-alanine in drug discovery. carnosine has been rese. Synonyms: 2-Carboxyethylamine; 3-Aminopropanoic Acid; 3-Aminopropionic Acid; Abufene; NSC 7603; β-Aminopropanoic Acid; β-Aminopropionic Acid; ω-Aminopropionic Acid. Grade: 98%. CAS No. 107-95-9. Mole | |
| BMS711939 | BMS711939 is a selective and potent peroxisome proliferator-activated receptor α(PPARα) agonist with EC50 value of 4 nM for human PPARα. It is >1000-fold selectivity vs human PPARγ with EC50 value of 4.5 μM and PPARδ with EC50 value of > 100 μM in PPAR-GAL4 transactivation assays. It shows excellent in vivo efficacy and safety profiles in preclinical studies. It was chosen for further preclinical evaluation. Uses: Bms711939 was chosen for further preclinical evaluation. Synonyms: BMS-711939; BMS 711939; BMS711939. Glycine, N-((5-((2-(4-chlorophenyl)-5-methyl-4-oxazolyl)methoxy)-2-fluorophenyl)methyl)-N-(methoxycarbonyl)-; 2-[[5-[[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy]-2-fluorophenyl]methyl-methoxycarbonylamino]acetic acid. Grade: >98 %. CAS No. 1000998-62-8. Molecular formula: C22H20ClFN2O6. Mole weight: 462.86. | |
| Boc-D-2,3-diaminopropionic acid | Boc-D-2,3-diaminopropionic acid (N-t-Boc-amino-D-alanine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize a potent NMDA receptor glycine site agonist with GluN2 subunit-specific activity [1]. Uses: Scientific research. Group: Peptides. Alternative Names: N-t-Boc-amino-D-alanine; Boc-D-Dap-OH. CAS No. 76387-70-7. Pack Sizes: 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W014692. | |
| CAY10608 | The N-methyl-D-aspartate receptor (NMDA) is a glutamate receptor and ion channel protein found in nerve cells. The NMDA receptor is one of three types of ionotropic glutamate receptors. The other receptors are the AMPA and kainate receptors. NMDA is Ca2+ permeable ligand-gated channels of the central nervous system that are activated after binding of the co-agonists glutamate and glycine. CAY10608 is a propanolamine that potently, selectively, and non-competitively antagonizes the NR2B subunit of NMDA receptors with IC50 of 50 nM. Synonyms: CAY 10608; CAY-10608. Grade: ≥98%. CAS No. 457897-92-6. Molecular formula: C18H22Cl2N2O4S. Mole weight: 433.4. | |
| CGP 35348 (GABAB Receptor Antagonist, CGP 35348, CGP35348, CGP-35348) | A selective antagonist of post-synaptic GABAB receptors (IC50 = 34uM) that can permeate the blood brain barrier. Exhibits about 10-fold lower affinity for pre-synaptic receptors. Blocks K+-evoked glycine exocytosis in mouse spinal cord and hippocampal nerve endings. Shown to antagonize the potentiating effect of L-baclofen on noradrenaline-induced stimulation of adenylate cyclase in rat cortex slices. Group: Biochemicals. Grades: Highly Purified. CAS No. 123690-79-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CGP 78608 hydrochloride | CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor , with an IC 50 of 6 nM. CGP 78608 hydrochloride acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC 50 in the low nM range (26.3 nM). Anticonvulsant activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1135278-54-4. Pack Sizes: 1 mg. Product ID: HY-107701. | |
| CIQ ((3-Chlorophenyl) [3, 4-dihydro-6, 7-dimethoxy-1- [ (4-methoxyphenoxy) methyl] -2 (1H) -isoquinolinyl] methanone) | A positive allosteric modulator selective for NR2C/D containingnMDA receptors (EC50 = 2.7 and 2.8uM for NR2C and NR2D, respectively). Increases channel opening frequency of recombinant NR2C/D containingnMDA receptors by two-fold without altering mean open time or EC50 values for glutamate or glycine bindings. No effect on NR2A or NR2B subtypes. Group: Biochemicals. Grades: Highly Purified. CAS No. 486427-17-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| CNQX | CNQX, also known as FG9065, is a potent and competitive AMPA/kainate receptor antagonist and also an antagonist at glycine modulatory site on NMDA receptor complex. Uses: Excitatory amino acid antagonists. Synonyms: FG 9065; FG-9065; FG9065; 6-Cyano-2,3-dihydroxy-7-nitroquinoxaline; 1,4-dihydro-2,3-dihydroxy-7-nitro-6-quinoxalinecarbonitrile. Grade: 98%. CAS No. 115066-14-3. Molecular formula: C9H4N4O4. Mole weight: 232.15. | |
| CNQX (6-Cyano-7-nitroquinoxaline-2,3-dione, 6-Cyano-2,3-dihydroxy-7-nitro-quinoxaline) | A potent and competitive antagonist for AMPA/kainate receptors (Ki = 0.6-2.11uM for GluA1-4 and Ki = 1.3-5.3uM for different subtypes of Kainate receptors) and a negative allosteric modulator atnMDA receptor glycine binding site. Widely used for assessing the functional roles of neurotransmission mediated by glutamate receptors in both normal and abnormal brain functions. Group: Biochemicals. Grades: Highly Purified. CAS No. 115066-14-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Colchicine | Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC 50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 64-86-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-16569. | |
| Commendamide | Commendamide is a natural bacterial product which was discovered in a screen for commensal bacteria effector genes (Cbegs). Commendamide is structurally similar to long-chain N-acyl-amides, which commonly signal, in mammals, through G protein-coupled receptors. Commendamide activates GPR132 (also known as G2A) with an EC50 value of 11.8 μM. Synonyms: N-acyl-3-hydroxypalmitoyl-Glycine; 2-(3-hydroxyhexadecanoylamino)acetic acid. Grade: ≥95%. CAS No. 193825-78-4. Molecular formula: C18H35NO4. Mole weight: 329.5. | |
| Cycloleucine | Cycloleucine is a competitive inhibitor of glycine modulatory site of N-methyl-D-aspartate (NMDA) receptor, with immunosuppressive, antineoplastic and cytostatic activities. It competitively inhibits methionine adenosyltransferase, thereby inhibiting S-adenosylmethionine (SAM) synthesis from methionine and ATP, and subsequent nucleic acid methylation and polyamine production. Synonyms: 1-Aminocyclopentanecarboxylic acid; 1-Amino-1-cyclopentanecarboxylic acid; 1-Amino-1-carboxycyclopentane; NSC 1026; NSC 112194; NSC 112195; NSC 112197; ACPC. Grade: ≥98%. CAS No. 52-52-8. Molecular formula: C6H11NO2. Mole weight: 129.16. | |
| Cycloleucine | Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation. Cycloleucine is antagonist of NMDA receptor associated glycine receptor, with a K i of 600 μM. Cycloleucine is also a competitive inhibitor of ATP: L-methionine-S-adenosyl transferase in vitro. Cycloleucine has anxiolytic and cytostatic effects [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52-52-8. Pack Sizes: 25 mg. Product ID: HY-30008. | |
| D-(-)-2-Phenylglycine | D-(-)-2-Phenylglycine is the derivative of glycine, a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. It is also an impurity of Ampicillin and Cefaclor. Synonyms: Ampicillin EP Impurity L; Cefaclor EP Impurity A; (-)-(R)-Phenylglycine; (-)-Phenylglycine; (2R)-Amino-2-phenylethanoic Acid; (R)-(-)-2-Phenylglycine; (R)-2-Amino-2-phenylacetic Acid; (R)-2-Amino-2-phenylethanoic Acid; (R)-2-Phenyl-2-aminoethanoic Acid; (R)-2-Phenylglycine; (R)-2-Phenylglycine. Grade: ≥ 99% (Assay). CAS No. 875-74-1. Molecular formula: C8H9NO2. Mole weight: 151.17. | |
| D-Alanine | D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC 50 of 9 mM for GlyR [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-Alanine; Ba 2776; D-α-Alanine. CAS No. 338-69-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-41700. | |
| D-Phenylglycine 99+% | D-(-)-2-Phenylglycine is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. Group: Biochemicals. Alternative Names: D-Phg-OH; (-)-(R)-Phenylglycine; (-)-Phenylglycine; (2R)-Amino-2-phenylethanoic Acid; (R)-(-)-2-Phenylglycine; (R)-2-Amino-2-phenylacetic Acid; (R)-2-Amino-2-phenylethanoic Acid; (R)-2-Phenyl-2-aminoethanoic Acid; (R)-2-Phenylglycine; (R)-2-Phenylglycine; (R)-Phenylglycine; (R)-Phenylglycine; (R)-α-Phenylglycine; D-(-)-Aminophenylacetic Acid; D-(-)-Phenylglycine; D-(-)-α-Aminophenylacetic Acid; D-(-)-α-Phenylglycine; D-2-Phenylglycine; D-C-Phenylglycine; D-Phenylglycine; D-α-Aminophenylacetic Acid; D-α-Phenylglycine; D-2-Phenylglycine; (R)-α-Aminobenzeneacetic Acid; (αR)-α-Aminobenzeneacetic Acid. Grades: Reagent Grade. CAS No. 875-74-1. Pack Sizes: 25g, 100g, 250g, 500g, 1Kg. US Biological Life Sciences. | Worldwide |
| [D-Trp8]-γ-MSH | [D-Trp8]-γ-MSH is a selective melanocortin 3 (MC3) receptor agonist (IC50= 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively). It displays antiinflammatory efficacy in mice bearing a non-functional MC1R (recessive yellow e/e mouse) and these effects are abrogated in the presence of the HO-1 inhibitor ZnPPIX. Synonyms: L-tyrosyl-L-valyl-L-methionyl-glycyl-L-histidyl-L-phenylalanyl-L-arginyl-D-tryptophyl-L-alpha-aspartyl-L-arginyl-L-phenylalanyl-glycine. CAS No. 321351-81-9. Molecular formula: C74H99N21O16S. Mole weight: 1570.79. | |
| Farampator | Farampator, also called as CX-691 or Org24448, is an AMPA receptor positive allosteric modulator and glycine reuptake inhibitor potentially for the treatment of schizophrenia. Synonyms: 2,1,3-benzoxadiazol-5-yl(piperidin-1-yl)methanone; 1-(benzofurazan-5-ylcarbonyl)piperidine; 5-(1-piperidinylcarbonyl)-2,1,3-benzoxadiazole ; farampator; Org-24448; CX-691; Org 24448; CX 691; Org24448; CX691. CAS No. 211735-76-1. Molecular formula: C12H13N3O2. Mole weight: 231.25. | |
| Flavine Adenine Dinucleotide-13C5 Ammonium Salt | Labelled Flavine Adenine Dinucleotide. The prosthetic group of certain flavoproteins including D-amino acid oxidase, glucose oxidase, glycine oxidase, fumaric hydrogenase, histaminase, and xanthine oxidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase. Synonyms: Riboflavin 5'-(Trihydrogen Diphosphate) P'5'-Ester with Adenosine-13C5 Ammonium Salt; Adenine-flavine Dinucleotide-13C5 Disodium; Adenine-riboflavin-13C5 Dinucleotide Ammonium Salt; Adenine-riboflavine-13C5 Dinucleotide Ammonium Salt; FAD-13C5 Ammonium Salt; Fademin-13C5 Ammonium Salt; Flavinat-13C5 Ammonium Salt; Flavine Adenosine Diphosphate-13C5 Ammonium Salt; Flavitan-13C5 Ammonium Salt; NSC 112207; Riboflavin-adenine Dinucleotide-13C5 Dinucleotide Ammonium Salt. Grade: 95%; 99% atom 13C. Molecular formula: C22[13C]5H33N9O15P2 xNH3. Mole weight: 790.51. | |
| Flavine Adenine Dinucleotide Disodium Salt | The prosthetic group of certain flavoproteins including D-amino acid oxidase, glucose oxidase, glycine oxidase, fumaric hydrogenase, histaminase, and xanthine oxidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase. Group: Biochemicals. Alternative Names: Riboflavin 5'-(Trihydrogen Diphosphate) P'5'-Ester with Adenosine. Grades: Highly Purified. CAS No. 146-14-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Galanin (swine) | Galanin (swine), a neuropeptide, consists of 29 amino acids and contains a C-terminal amidated glycine. Galanin (swine) inhibits basal and stimulated insulin secretion both in vivo and in vitro under a variety of experimental conditions. Galanin (swine) is a galanin receptor agonist with pK i s of 9.63, 9.49, 9.02, 8.98, 8.01 and 8.14 at human GAL1, rat GAL1, human GAL2, rat GAL2, human GAL3 and rat GAL3 respectively [1]. Uses: Scientific research. Group: Peptides. CAS No. 88813-36-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1128. | |
| gamma-DGG acetate | gamma-DGG acetate is a competitive blocker of AMPA receptor and is a broad spectrum glutamate receptor (GluR) antagonist. Synonyms: H-D-gGlu-Gly-OH.CH3CO2H; D-gamma-glutamyl-glycine acetic acid; N5-(carboxymethyl)-D-glutamine compound with acetic acid (1:1); γ-DGG acetate salt; γ-D-Glutamylglycine acetate salt. Grade: ≥95%. CAS No. 2935387-13-4. Molecular formula: C7H12N2O5.C2H4O2. Mole weight: 264.23. | |
| Gavestinel | Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GV 150526. CAS No. 153436-22-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-150138. | |
| Gavestinel | Gavestinel is a non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (Kd = 0.8 nM), displaying >1000-fold selectivity over NMDA, AMPA, and kainate binding sites. Gavestinel exhibits a neuroprotective property in animal models of ischaemic stroke. Uses: Glycine agents. Synonyms: 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]-; 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-; 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[3-oxo-3-(phenylamino)-1-propenyl]-, (E)-; 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]-1H-indole-2-carboxylic acid; GV 150526; GV 150526X; (E)-4,6-dichloro-3-(3-oxo-3-(phenylamino)prop-1-en-1-yl)-1H-indole-2-carboxylic acid. Grade: ≥95%. CAS No. 153436-22-7. Molecular formula: C18H12Cl2N2O3. Mole weight: 375.21. | |
| Gavestinel sodium salt | Gavestinel is a non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (Kd = 0.8 nM), displaying > 1000-fold selectivity over NMDA, AMPA and kainate binding sites. Gavestinel exhibits a neuroprotective property in animal models of ischaemic stroke. Synonyms: 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]-, sodium salt (1:1); 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-, monosodium salt; 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[3-oxo-3-(phenylamino)-1-propenyl]-, monosodium salt, (E)-; GV 150526A. Grade: ≥98% by HPLC. CAS No. 153436-38-5. Molecular formula: C18H11Cl2N2O3Na. Mole weight: 397.19. | |
| Gelsevirine | Gelsevirine, isolated from the herbs of Gelsemium elegans, could be developed as the treatment of anxiety-related disorders in human patients. Their anxiolytic mechanism may be involved in the agonist action of glycine receptor in the brain. Uses: Anxiolytic. Synonyms: Gelsemine, 1-methoxy-; 1-Methoxygelsemine. Grade: >98%. CAS No. 38990-03-3. Molecular formula: C21H24N2O3. Mole weight: 352.4. | |
| [Gly9-OH]-Atosiban | An impurity of Atosiban. Atosiban is a synthetic peptide that acts as a selective oxytocin receptor antagonist, primarily used to delay preterm labor in pregnant women. Synonyms: Mpr-D-Tyr(Et)-Ile-Thr-Asn-Cys-Pro-Orn-Gly(Mpr1&Cys6 bridge); Atosiban (free acid); (Deamino-Cys1,D-Tyr(Et)2,Thr4,Orn8)-Oxytocin (free acid); 3-Mercaptopropionyl-D-Tyr(Et)-Ile-Thr-Asn-Cys-Pro-Orn-Gly-OH (Disulfide bond); deamino-Cys-D-Tyr(Et)-Ile-Thr-Asn-Cys-Pro-Orn-Gly-OH (Disulfide bridge: Cys1-Cys6); Deamino-cysteinyl-O4-ethyl-D-tyrosyl-L-isoleucyl-L-threonyl-L-asparagyl-L-cysteinyl-L-prolyl-L-ornithyl-glycine (1->6)-disulfide; Glycine, O-ethyl-N-(3-mercapto-1-oxopropyl)-D-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-, cyclic (1→5)-disulfide; Gly9-Atosiban; [Gly9]-Atosiban; Gly(9)-Atosiban. Grade: ≥95%. CAS No. 168102-69-0. Molecular formula: C43H66N10O13S2. Mole weight: 995.19. | |
| Glycine | Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 56-40-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-Y0966. | |
| Glycine-13C | Labelled analogue of Glycine, a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. Group: Biochemicals. Alternative Names: 2-Aminoacetic Acid-13C. Grades: Highly Purified. CAS No. 20220-62-6. Pack Sizes: 10mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| Glycine-13C2 | Glycine- 13 C 2 is the 13 C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 67836-01-5. Pack Sizes: 10 mg; 25 mg. Product ID: HY-Y0966S3. | |
| Glycine-13C2 | Isotope labelled Glycine is a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 67836-01-5. Pack Sizes: 25mg, 50mg. Molecular Formula: 13C2H5NO2. US Biological Life Sciences. | Worldwide |
| Glycine-13C2,15N | Labeled analogue of Glycine, a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. Group: Biochemicals. Alternative Names: 2-Aminoacetic Acid-13C2,15N. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Glycine-15N | Glycine- 15 N is the 15 N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 7299-33-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-Y0966S. | |
| Glycine-15N | Glycine-15N is the labelled form of Glycine (G615990). Glycine is a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 7299-33-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C2H515NO2, Molecular Weight: 76.06. US Biological Life Sciences. | Worldwide |
| Glycine-2-13C | Glycine-2- 13 C is the 13 C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 20220-62-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-Y0966S2. | |
| Glycine-2-13C,15N | Glycine-2- 13 C, 15 N is the 13 C- and 15 N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 91795-59-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-Y0966S7. | |
| Glycine-β-muricholic Acid | Glycine-β-muricholic acid (GβMCA) is a potent, oral bioactive and intestine-selective antagonist of the farnesoid X receptor (FXR) that may be a candidate for the treatment of metabolic disorders. Synonyms: Gly-MCA; GβMCA; N-[(3α,5β,6β,7β)-3,6,7-trihydroxy-24-oxocholan-24-yl]-glycine; 5β-Cholanic acid-3α,6β,7β-triol N-(carboxymethyl)-amide. Grade: ≥95%. CAS No. 66225-78-3. Molecular formula: C26H43NO6. Mole weight: 465.63. | |
| Glycine Hydrochloride | Glycine hydrochloride is a salt of Glycine which is a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. Group: Biochemicals. Alternative Names: H-Gly-OH·HCl; Aminoacetic Acid Hydrochloride; Carboxymethanaminium Chloride; Glycocoll Hydrochloride. Grades: Highly Purified. CAS No. 6000-43-7. Pack Sizes: 250g, 500g. Molecular Formula: C?H?ClNO?, Molecular Weight: 111.53. US Biological Life Sciences. | Worldwide |
| Glycine Hydrochloride | Glycine hydrochloride is a salt of glycine which is a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. Synonyms: Aminoacetic Acid Hydrochloride; Aminoethanoic Acid; Glycocoll Hydrochloride; 2-aminoacetic acid,hydrochloride. Grade: ? 98%. CAS No. 6000-43-7. Molecular formula: C2H6ClNO2. Mole weight: 111.53. | |
| Glycine (Standard) | Glycine (Standard) is the analytical standard of Glycine. This product is intended for research and analytical applications. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 56-40-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Y0966R. | |
| Glycylglycine (Gly-Gly, Diglycine) | N-Glycylglycine is a derivative of Glycine, a non-essential amino acid that enhances N-methyl-D-aspartate (NMDA) receptor mediated synaptic potentials in the neocortex of rats. Glycine is also being used as adjuvant therapy for the treatment of schizophrenia. Group: Biochemicals. Alternative Names: Gly-Gly, Diglycine;18: PN: WO2012015910 SEQID: 19 Unclaimed Sequence; 1: PN: WO2010117786 PAGE: 166 Claimed Protein; 2-(Aminoacetamido)acetic Acid; 221: PN: EP2161028 PAGE: 11 Claimed Protein; 31: PN: FR2860236 PAGE: 10 Claimed Protein; 36: PN: EP2204377 SEQID: 36 Claimed Protein; 36: PN: WO2010076654 SEQID: 36 Claimed Protein; 69: PN: US20110195077 SEQID: 14 Claimed Sequence; 6: PN: WO2013027191 SEQID: 14 Claimed Sequence; Diglycine; Diglycocoll; Gly2; Glycine Dipeptide; N-Glycylglycine; NSC 49346; α-Glycylglycine. Grades: Molecular Biology Grade. CAS No. 556-50-3. Pack Sizes: 100g, 250g, 500g, 1Kg, 5Kg. Molecular Formula: C?H?N?O?, Molecular Weight: 132.12. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
