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| Product | Description | |
|---|---|---|
| 1-Boc-3-hydroxy methyl pyrrolidine | 1-Boc-3-hydroxy methyl pyrrolidine. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences. |  Worldwide |
| 1-Methyl-3 (hydroxy- (3-pyridyl) methyl) Pyrrolidine. (Mixture of diastereomers) | A nicotine derivative. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 2-Pyrrolidineaceticacid,-alpha--hydroxy-,methylester,(2S)-(9ci) | 2-Pyrrolidineaceticacid,-alpha--hydroxy-,methylester,(2S)-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Pyrrolidineaceticacid,-alpha--hydroxy-,methylester,(2S)-(9CI). Product Category: Heterocyclic Organic Compound. CAS No. 603956-68-9. Molecular formula: C7H13NO3. Product ID: ACM603956689. Alfa Chemistry ISO 9001:2015 Certified. |  |
| (2R)-2-[(1E)-3-(4'-Chloro-2'-methyl[1,1'-biphenyl]-3-yl)-3-hydroxy-1-propen-1-yl]-5-oxo-1-pyrrolidineheptanoic Acid | (2R)-2-[(1E)-3-(4'-Chloro-2'-methyl[1,1'-biphenyl]-3-yl)-3-hydroxy-1-propen-1-yl]-5-oxo-1-pyrrolidineheptanoic Acid is an EP4 receptor agonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 493035-81-7. Pack Sizes: 500ug, 1mg. Molecular Formula: C27H32ClNO4, Molecular Weight: 470. US Biological Life Sciences. | Worldwide |
| (2R,3S,4S,5R)-3-Hydroxy-5-[(methylamino)carbonyl]-4-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester | (2R,3S,4S,5R)-3-Hydroxy-5-[(methylamino)carbonyl]-4-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester is a compound widely studied in biomedicine, exhibiting significant potential in the treatment of a wide range of diseases. Its mechanism of action involves targeting specific molecular pathways and receptors linked to drug-resistant cancers, neurodegenerative disorders, and infectious diseases. CAS No. 1591782-89-6. Molecular formula: C26H34N2O6. Mole weight: 470.56. |  |
| (2R, 4R) -2- [ [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] methyl] -4-hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester | (2R, 4R) -2- [ [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] methyl] -4-hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of 2-epi-Lincomycin which is an epimer of Lincomycin (L466200) which is a 6-amino, 6-deoxy-octopyraninose with strong antibiotic activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 216062-16-7. Pack Sizes: 50mg, 100mg. Molecular Formula: C16H33NO4Si. US Biological Life Sciences. | Worldwide |
| (2R, 4R) -2-[[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]methyl]-4-hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester | (2R, 4R) -2-[[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]methyl]-4-hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of Lincomycin, which is a lincosamide antibiotic from the actinomycete Streptomyces lincolnensis. Synonyms: 2-Methyl-2-propanyl (2R,4R)-2-({[dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-4-hydroxy-1-pyrrolidinecarboxylate; 1-Pyrrolidinecarboxylic acid, 2-[[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]methyl]-4-hydroxy-, 1,1-dimethylethyl ester, (2R,4R)-. Grades: ≥95%. CAS No. 216062-16-7. Molecular formula: C16H33NO4Si. Mole weight: 331.52. | |
| (2S,3S)-1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic acid methyl ester | (2S,3S)-1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic acid methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (2S,3S)-1-(Tert-butoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic acid methyl ester;(2S,3S)-3-Hydroxy-1,2-pyrrolidinedicarboxylic acid 1-tert-butyl 2-methyl ester. Product Category: Heterocyclic Organic Compound. CAS No. 184046-78-4. Molecular formula: C11H19NO5. Mole weight: 245.272260 [g/mol]. Purity: 0.96. IUPACName: 1-O-tert-butyl 2-O-methyl (2S,3S)-3-hydroxypyrrolidine-1,2-dicarboxylate. Canonical SMILES: CC(C)(C)OC(=O)N1CCC(C1C(=O)OC)O. Density: 1.216. Product ID: ACM184046784. Alfa Chemistry ISO 9001:2015 Certified. | |
| (2S, 3S) -3- hydroxy-1, 2-pyrrolidinedicarboxyl ic acid 1-tert-Butyl 2-Methyl Ester | (2S, 3S) -3- hydroxy-1, 2-pyrrolidinedicarboxyl ic acid 1-tert-butyl 2-methyl ester is a reactant used to improve potency of imidazo[1,2-b]pyridazines as IKK β inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 184046-78-4. Pack Sizes: 25mg, 250mg. Molecular Formula: C11H19NO5, Molecular Weight: 245.27. US Biological Life Sciences. | Worldwide |
| (2S) -4- hydroxy-4-propyl -1, 2-pyrrolidinedicarboxyl ic Acid 1-Benzyl 2-Methyl Ester | Intermediate in the preparation of Dehydro 7-Epi Clindamycin (D229595). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (2S,4R)-1-((R)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride | (2S,4R)-1-((R)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2761478-98-0. Molecular Formula: C22H31ClN4O3S. Mole Weight: 467.03. Catalog: APB2761478980. |  |
| (2S, 4R) -1- ( (S) -2- (1-Cyanocyclopropane carboxamido) -3, 3-di methyl butanoyl) -4-hydroxy-N- (4- (4- methyl thiazol-5-yl) benzyl) pyrrolidine-2-carboxamide | (2S, 4R) -1- ( (S) -2- (1-Cyanocyclopropane carboxamido) -3, 3-di methyl butanoyl) -4-hydroxy-N- (4- (4- methyl thiazol-5-yl) benzyl) pyrrolidine-2-carboxamide is a VHL inhibitors that decreases hypoxia inducible factor-α during hypoxia associated signaling in human cervical cancer, osteosarcoma HeLa and U2OS. cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 2097381-85-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C27H33N5O4S, Molecular Weight: 523.65. US Biological Life Sciences. | Worldwide |
| (2S,4R)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide | (2S,4R)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: VH032-cyclopropane-F. Product Category: E3 Ligase Ligand. CAS No. 2306193-99-5. Molecular formula: C26H33FN4O5S. Mole weight: 532.6274. Purity: 0.95. IUPACName: (2S,4R)-1-[(2S)-2-[(1-fluorocyclopropanecarbonyl)amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[2-hydroxy-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide. Product ID: PR2306193995. Alfa Chemistry ISO 9001:2015 Certified. | |
| (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide | (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (S,R,S)-AHPC. Product Category: PROTAC Library. CAS No. 1448297-52-6. Molecular formula: C22H30N4O3S. Mole weight: 430.5636. Purity: 0.99. IUPACName: (2S,4R)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide. Product ID: PR1448297526. Alfa Chemistry ISO 9001:2015 Certified. | |
| (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide Hydrochloride | (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide Hydrochloride acts as a reagent in the synthesis of PROTAC compounds that mediated the degration of oncogenic c-ABL and BCR-ABL. Group: Biochemicals. Grades: Highly Purified. CAS No. 1448189-80-7. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C22H30N4O3S; (HCl), Molecular Weight: 430.563646. US Biological Life Sciences. | Worldwide |
| (2S, 4R) -2-[ (Dimethylamino) carbonyl]-4-hydroxy-1-pyrrolidinecarboxylic Acid-d6 4-Nitrobenzyl Ester | Intermediate in the production of labeled Meropenem. Group: Biochemicals. Alternative Names: (2S-trans) -2-[ (Dimethylamino) carbonyl]-4-hydroxy-1-pyrrolidinecarboxylic Acid-d6 (4-Nitrophenyl)methyl Ester. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (2S,4R)-4-Hydroxy-1-methyl-2-pyrrolidinemethanol | (2S,4R)-4-Hydroxy-1-methyl-2-pyrrolidinemethanol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SCHEMBL5321769, IXFHJDFJPFHQLP-NTSWFWBYSA-N, AJ-98012, DB-059660, (2S, 4R)-4-hydroxy-1-methyl-2-pyrrolidinemethanol, (2S,4R)-4-hydroxy-1-methyl-2-Pyrrolidinemethanol, 107797-60-4. Product Category: Heterocyclic Organic Compound. CAS No. 107797-60-4. Molecular formula: C6H13NO2. Mole weight: 131.172920 [g/mol]. Purity: 0.96. IUPACName: (3R,5S)-5-(hydroxymethyl)-1-methylpyrrolidin-3-ol. Canonical SMILES: CN1CC(CC1CO)O. Product ID: ACM107797604. Alfa Chemistry ISO 9001:2015 Certified. | |
| (2S,4R)-4-Hydroxy-2-(hydroxymethyl)-1-pyrrolidinecarboxylic Acid tert-Butyl Ester | A useful reactant used in the preparation of 4-purinylpyrrolidine nucleosides, kinase inhibitors and antibacterial agents. Group: Biochemicals. Alternative Names: (2S,4R)-tert-Butyl 4-Hydroxy-2- (hydroxymethyl) pyrrolidine-1-carboxylate; N-Boc-trans-4-hydroxy-L-prolinol; tert-Butyl (2S, 4R) -4-Hydroxy-2- (hydroxymethyl) pyrrolidine-1-carboxylate; tert-Butyl (2S, 4R) -4-Hydroxy-2-hydroxy methyl pyrrolidine-1-carboxylate. Grades: Highly Purified. CAS No. 61478-26-0. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| (2S,4S)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[(4-(4-methyl-1,3-thiazol-5-yl)phenyl)methyl]pyrrolidine-2-carboxamide | (2S,4S)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[(4-(4-methyl-1,3-thiazol-5-yl)phenyl)methyl]pyrrolidine-2-carboxamide. Uses: Designed for use in research and industrial production. Product Category: E3 Ligase Ligand. CAS No. 1797406-78-0. Molecular formula: C22H30N4O3S. Mole weight: 430.5636. Purity: 0.95. IUPACName: (2S,4S)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide. Product ID: PR1797406780. Alfa Chemistry ISO 9001:2015 Certified. | |
| (2S, 4S) -4- hydroxy-1, 2-pyrrolidinedicarboxyl ic Acid 1-[(4-nitrophenyl)methyl] Ester | (2S, 4S) -4- hydroxy-1, 2-pyrrolidinedicarboxyl ic Acid 1-[(4-nitrophenyl)methyl] Ester. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. Molecular Formula: C13H14N2O7, Molecular Weight: 310.26. US Biological Life Sciences. | Worldwide |
| (2S) -N- [ (1S) -1- (Hydroxydiphenyl methyl ) -3- methyl butyl] -2-pyrrolidinecarboxamide | (2S) -N- [ (1S) -1- (Hydroxydiphenyl methyl ) -3- methyl butyl] -2-pyrrolidinecarboxamide . Group: Biochemicals. Alternative Names: N- [ (1S) -1- (Hydroxydiphenyl methyl ) -3- methyl butyl] -L-prolinamide; (S)-N-[(S)-1-Hydroxy-4-methyl-1,1-diphenylpentan-2-yl]pyrrolidine-2-carboxamide; Singh's Catalyst. Grades: Highly Purified. CAS No. 910110-45-1. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. US Biological Life Sciences. | Worldwide |
| 3-(Hydroxymethyl)-1-oxy-2,2,5,5-tetramethylpyrrolidine | 3- (Hydroxy methyl ) -1-oxy-2, 2, 5, 5-tetra methyl pyrrolidine. Group: Biochemicals. Alternative Names: 3-(Hydroxymethyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy. Grades: Highly Purified. CAS No. 27298-75-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C9H18NO2. US Biological Life Sciences. | Worldwide |
| 3-Hydroxy methyl - (1-oxy-2, 2, 5, 5-tetra methyl pyrrolidine) . | A reactive spin label. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 4-Hydroxy-2-oxo-1-pyrrolidineacetic Acid Methyl Ester | 4-Hydroxy-2-oxo-1-pyrrolidineacetic Acid Methyl Ester is an impurity of the nootropic Oxiracetam. Group: Biochemicals. Alternative Names: Methyl 4-Hydroxy-2-oxo-1-pyrrolidineacetate; Oxiracetam Impurity C. Grades: Highly Purified. CAS No. 85614-52-4. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| (βS)-α-hydroxy-β-[[(2S)-4-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]pentyl]amino]-2-oxo-3-pyrrolidinepropanesulfonic acid, monosodium salt | (βS)-α-hydroxy-β-[[(2S)-4-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]pentyl]amino]-2-oxo-3-pyrrolidinepropanesulfonic acid, monosodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GC376 (sodium salt). Appearance: Crystalline solid. CAS No. 1416992-39-6. Molecular formula: C21H30N3NaO8S. Mole weight: 507.5. Purity: 0.9. IUPACName: sodium;(2S)-1-hydroxy-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate. Canonical SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CC1CCNC1=O)C(O)S(=O)(=O)[O-])NC(=O)OCC2=CC=CC=C2.[Na+]. Product ID: ACM1416992396. Alfa Chemistry ISO 9001:2015 Certified. | |
| Pyrrolidine,1-hydroxy-2-[(2-propenyloxy)methyl]-,(2S)-(9ci) | Pyrrolidine,1-hydroxy-2-[(2-propenyloxy)methyl]-,(2S)-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pyrrolidine, 1-hydroxy-2-[(2-propenyloxy)methyl]-, (2S)- (9CI). Product Category: Heterocyclic Organic Compound. CAS No. 403477-64-5. Molecular formula: C8H15NO2. Mole weight: 157.2102. Product ID: ACM403477645. Alfa Chemistry ISO 9001:2015 Certified. | |
| (S)-13-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-14,14-dimethyl-11-oxo-3,6,9-trioxa-12-azapentadecanoic acid | (S)-13-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-14,14-dimethyl-11-oxo-3,6,9-trioxa-12-azapentadecanoic acid. Uses: Designed for use in research and industrial production. Product Category: E3 Ligase Ligand-Linker. CAS No. 2172820-10-7. Molecular formula: C30H42N4O9S. Mole weight: 634.7409. Purity: 0.95. IUPACName: 2-[2-[2-[2-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-2-oxoethoxy]ethoxy]ethoxy]acetic acid. Product ID: PR2172820107. Alfa Chemistry ISO 9001:2015 Certified. | |
| 1-Benzyl-2,5-pyrrolidinedione | 1-Benzyl-2,5-pyrrolidinedione is an intermediate in synthesizing 2,3,4,10-Tetrahydro-1H-indolo[2,3-b][1,8]naphthyridin-2-ol (T294270), a derivative of 6, 7, 8, 9-Tetrahydro-7-hydroxy-5-methyl-3-phenyl-pyrido[3, 2:4, 5]imidazo[1, 2-a]pyrimidinium Chloride (H957770), a carcinogen used in the study of intestinal bacteria metabolism. Created through the heat processing of food. Group: Biochemicals. Grades: Highly Purified. CAS No. 2142-6-5. Pack Sizes: 500mg, 1g. Molecular Formula: C11H11NO2. US Biological Life Sciences. | Worldwide |
| 1-Benzylpyrrolidin-3-yl-methanol | 1-Benzylpyrrolidin-3-yl-methanol. Group: Biochemicals. Alternative Names: 1-N-Benzyl-3-hydroxy methyl pyrrolidine; 1-Benzyl-DL-b-prolinol. Grades: Highly Purified. CAS No. 5731-17-9. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| 2- (Hydroxy- (4-nitrophenyl) methyl) cyclopentanone | 2- (Hydroxy- (4-nitrophenyl) methyl) cyclopentanone is used in the preparation of hydroxyketones via aldol reaction of aryl aldehydes with ketones catalyzed by polyanilino methyl pyrrolidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 205759-66-6. Pack Sizes: 50mg, 250mg. Molecular Formula: C12H13NO4, Molecular Weight: 235.24. US Biological Life Sciences. | Worldwide |
| (2R)-2-Pyrrolidinemethanol | (2R)-2-Pyrrolidinemethanol. Group: Biochemicals. Alternative Names: (2R) -2-Hydroxy methyl pyrrolidine; (2R)-2-Pyrrolidinemethanol; (2R)-Pyrrolidin-2-ylmethanol; (R) - (-) -2- (Hydroxymethyl) pyrrolidine; (R)-(-)-Pyrrolidine-2-methanol; (R)-1-(Pyrrolidin-2-yl)methanol; (R)-1-Pyrrolidin-2-yl-methanol; (R) -2- (Hydroxymethyl) pyrrolidine; (R)-2-Pyrrolidinemethanol; (R)-Prolinol; (R)-Pyrrolidin-2-methanol; (R)-Pyrrolidin-2-ylmethanol; (R)-Pyrrolidine-2-yl methanol; D-Prolinol; (-)-2-Pyrrolidinemethanol; (2-(D)-Pyrrolidinyl)methanol. Grades: Highly Purified. CAS No. 68832-13-3. Pack Sizes: 2.5g. Molecular Formula: C5H11NO, Molecular Weight: 101.15. US Biological Life Sciences. | Worldwide |
| (2S)-4'-Depropyl-4'-propylidenelincomycin-d3 | (2S)-4'-Depropyl-4'-propylidenelincomycin-d3 is the labeled analog of (2S)-4'-Depropyl-4'-propylidenelincomycin, a Lincomycin impurity, an antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial. Synonyms: Methyl-d3 6,8-Dideoxy-6-[[[(2S)-1-methyl-4-propylidene-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside; Methyl-d3 (2S)-6,8-Dideoxy-6-[[(1-methyl-4-propylidene-2-pyrrolidinyl)carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside; (S)-N-((1R,2R)-2-Hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-d3-4-propylidenepyrrolidine-2-carboxamide; 4'-Depropyl-4'-propylidenelincomycin-d3. Molecular formula: C18H29D3N2O6S. Mole weight: 407.54. | |
| (2S)-4'-Depropyl-4'-propylidenelincomycin (Mixture of Diastereomers) | (2S)-4'-Depropyl-4'-propylidenelincomycin is a Lincomycin impurity, an antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial. Synonyms: Lincomycin EP Impurity B; Methyl 6,8-Dideoxy-6-[[[(2S)-1-methyl-4-propylidene-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside; Methyl (2S)-6,8-Dideoxy-6-[[(1-methyl-4-propylidene-2-pyrrolidinyl)carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside; (S)-N-((1R,2R)-2-Hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylidenepyrrolidine-2-carboxamide; 4'-Depropyl-4'-propylidenelincomycin. Grades: 96%. CAS No. 37744-65-3. Molecular formula: C18H32N2O6S. Mole weight: 404.52. | |
| (2S, 4R) -4- hydroxy-1, 2-pyrrolidinedicarboxyl ic Acid 1-(4-Nitrobenzyl) Ester | Intermediate in the production of Meropenem. Group: Biochemicals. Alternative Names: (2S-trans) -4- hydroxy-1, 2-pyrrolidinedicarboxyl ic Acid 1-[(4-Nitrophenyl)methyl] Ester; (2S, 4R) -1- (p-Nitrobenzyl oxycarbonyl ) -4- hydroxyproline; trans-4- hydroxy-1- (4-nitrobenzyl oxycarbonyl ) -L-proline. Grades: Highly Purified. CAS No. 96034-57-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| AGB1 | AGB1, a potent, fast and highly selective bump-and-hole (B&H)-PROTAC degrader for BromoTag, exhibits degradation of Ab:Brd4BD2 L387A and Ab: BromoTag-Brd2 with pDC50s of 7.8 and 7.9, respectively. It has binary affinity for VHL (Kd = 125 nM), and has good pharmacokinetic characteristics in mice with a DC50 (6h) of ~13 nM. Synonyms: (S)-13-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-14,14-dimethyl-11-oxo-3,6,9-trioxa-12-azapentadecyl (R)-2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)butanoate. Grades: ≥95%. CAS No. 2776190-62-4. Molecular formula: C51H63ClN8O9S2. Mole weight: 1031.68. | |
| Alpha-cgrp(29-37)(canine,mouse,rat) | Alpha-cgrp(29-37)(canine,mouse,rat). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 219991-19-2. Product Category: Heterocyclic Organic Compound. CAS No. 219991-19-2. Molecular formula: C40H61N11O14. Mole weight: 919.977640 [g/mol]. Purity: 0.96. IUPACName: (4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S,3R)-3-hydroxy-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]-4-oxobutanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl. Canonical SMILES: CC(C)C(C(=O)NCC(=O)NC(CO)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(C(C)O)NC(=O)C2CCCN2. Product ID: ACM219991192. Alfa Chemistry ISO 9001:2015 Certified. Categories: a-CGRP (29-37) (canine. | |
| Antibiotic PF 1052 | Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma sp. It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively). Antibiotic PF 1052 inhibits neutrophil migration in a wound assay and reduces pseudopodia formation. Synonyms: (E)-5-(sec-Butyl)-3-((2-(2,3-dimethyloxiran-2-yl)-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)(hydroxy)methylene)-1-methylpyrrolidine-2,4-dione; PF 1052; 3-[[2-(2,3-Dimethyl-2-oxiranyl)-1,2,4a,5,6,7,8,8a-octahydro-6,8-dimethyl-1-naphthalenyl]hydroxymethylene]-1-methyl-5-(1-methylpropyl)-2,4-pyrrolidinedione. Grades: ≥95%. CAS No. 147317-15-5. Molecular formula: C26H39NO4. Mole weight: 429.59. | |
| ARCC-4 | ARCC-4 is a PROTAC, acting as an androgen receptor degrader. ARCC-4 is a low-nanomolar androgen receptor degrader able to degrade about 95% of cellular androgen receptors. It inhibits prostate tumor cell proliferation, degrades clinically relevant androgen receptor point mutants and unlike enzalutamide, retains antiproliferative effect in a high androgen environment. Synonyms: ARCC-4; 1973403-00-7; (2S,4R)-1-((S)-2-(2-(4-((4'-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1'-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; CHEMBL4540528; SCHEMBL17946930; DUPAJELXESPTNF-PPZGWQTASA-N; AKOS040741162; MS-31874; HY-130492; CS-0108331; EN300-7526556; Z3482428589; O1-(ABM-14 ether), O4-(Methylcarboxamide with AHPC) Butanediol; (2S,4R)-1-[(2S)-2-(2-{4-[(4'-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-[1,1'-biphenyl]-4-yl)oxy]butoxy}acetamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide. Grades: 99%. CAS No. 1973403-00-7. Molecular formula: C53H56F3N7O7S2. Mole weight: 1024.18. | |
| ARD-266 | ARD-266 is a highly potent and VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. ARD-266 effectively induces the degradation of AR protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines (DC50s = 0.2-1 nM). Synonyms: 2-Pyrrolidinecarboxamide, N- [ (1S) -3- [4- [2- [4- [ [ [trans-3- (3-chloro-4-cyanophenoxy) -2, 2, 4, 4-tetramethylcyclobutyl] amino] carbonyl] phenyl] ethynyl] -1-piperidinyl] -3-oxo-1-phenylpropyl] -4-hydroxy-1- [ (2R) -3-methyl-2- (3-methyl-5-isoxazolyl) -1-oxobutyl] -, (2S,4R)-; (2S, 4R) -N- ( (S) -3- (4- ( (4- ( ( (1r, 3r) -3- (3-chloro-4-cyanophenoxy) -2, 2, 4, 4-tetramethylcyclobutyl) carbamoyl) phenyl) ethynyl) piperidin-1-yl) -3-oxo-1-phenylpropyl) -4-hydroxy-1- ( (R) -3-methyl-2- (3-methylisoxazol-5-yl) butanoyl) pyrrolidine-2-carboxamide; (2S, 4R) -N- [ (1S) -3- [4- [2- [4- [ [ [trans-3- (3-Chloro-4-cyanophenoxy) -2, 2, 4, 4-tetramethylcyclobutyl] amino] carbonyl] phenyl] ethynyl] -1-piperidinyl] -3-oxo-1-phenylpropyl] -4-hydroxy-1- [ (2R) -3-methyl-2- (3-methyl-5-isoxazolyl) -1-oxobutyl] -2-pyrrolidinecarboxamide. Grades: ≥95%. CAS No. 2666951-70-6. Molecular formula: C52H59ClN6O7. Mole weight: 915.51. | |
| ARV-771 | ARV-771 is a potent BET bromodomain PROTAC® Degrader based on von Hippel-Lindau (VHL) E3 ligase, consisting of a BRD4-binding moiety bound to a VHL ligand via a linker. Synonyms: ARV 771; ARV771; (2S,4R)-1-((S)-2-(tert-butyl)-15-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,14-dioxo-6,10-dioxa-3,13-diazapentadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide; L-Prolinamide, N- [2- [3- [2- [ [2- [ (6S) -4- (4-chlorophenyl) -2, 3, 9-trimethyl-6H-thieno [3, 2-f] [1, 2, 4] triazolo [4, 3-a] [1, 4] diazepin-6-yl] acetyl] amino] ethoxy] propoxy] acetyl] -3-methyl-L-valyl-4-hydroxy-N- [ (1S) -1- [4- (4-methyl-5-thiazolyl) phenyl] ethyl] -, (4R)-; N- ({3-[2- ({[ (6S) -4- (4-Chlorophenyl) -2, 3, 9-trimethyl-6H-thieno[3, 2-f][1, 2, 4]triazolo[4, 3-a][1, 4]diazepin-6-yl]acetyl}amino) ethoxy]propoxy}acetyl) -3-methyl-L-valyl- (4R) -4-hydroxy-N-{ (1S) -1-[4- (4-methyl-1, 3-thiazol-5-yl) phenyl]ethyl}-L-prolinamide. Grades: ≥95%. CAS No. 1949837-12-0. Molecular formula: C49H60ClN9O7S2. Mole weight: 986.64. | |
| AT 1 | AT 1 is a highly selective BRD4 protein degrader composed of a BET bromodomain inhibitor (+)-JQ1 conjugated to a von Hippel-Lindau (VHL) ligand. Synonyms: BRD4 degrader AT1; (2S,4R)-1-((R)-2-acetamido-3-((6-(2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)hexyl)thio)-3-methylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. Grades: ≥98%. CAS No. 2098836-45-2. Molecular formula: C48H58ClN9O5S3. Mole weight: 972.68. | |
| AT6 | AT6 is an analogue of highly selective Brd4 degrader AT1, bearing thioether linkages of varying lengths. It led a dose-dependent degradation of BRD4 at concentration ranging in 30nM-3μM in HeLa cells. It works as a PROTAC selectively targeting on Brd4. Synonyms: AT 6; AT-6; (2S,4R)-1-((R)-14-acetamido-1-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-13,13-dimethyl-2-oxo-6,9-dioxa-12-thia-3-azapentadecan-15-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. CAS No. 2098836-50-9. Molecular formula: C48H58ClN9O7S3. Mole weight: 1004.68. | |
| AU-15330 | AU-15330 is highly specific and VHL-dependent PROTAC degrader of the SWI/SNF ATPase components (SMARCA2, SMARCA4 and PBRM1). It induces effective inhibition of tumour growth in xenograft models of prostate cancer and acts synergistically with enzalutamide, an AR antagonist. It induces disease remission in castration-resistant prostate cancer (CRPC) models and is nontoxic. Synonyms: AU 15330; AU15330; (2S,4R)-1-((S)-2-(2-(4-(3-Amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide. Grades: ≥95%. CAS No. 2380274-50-8. Molecular formula: C39H49N9O5S. Mole weight: 755.93. | |
| BMS561392 | BMS561392 is a tumor necrosis factor-alpha (TNF alpha) converting enzyme inhibitor. It has the potential treatment of diseases characterized by overproduction of TNF alpha, such as rheumatoid arthritis (RA). It was developed by Bristol-Myers Squibb and was in clinic phase 2 trials, but now it is terminated. Uses: Bms561392 has the potential treatment of diseases characterized by overproduction of tnf alpha, such as rheumatoid arthritis (ra). Synonyms: BMS-561392; BMS561392; BMS 561392; DPC-333; DPC 333; DPC333. (αR,?3R)?-3-Amino-N-hydroxy-α-(2-methylpropyl)?-3-[4-[(2-methyl-4-quinolinyl)?methoxy]?phenyl]?-2-oxo-1-pyrrolidineacetamide?;BMS-561392;DPC-333;(2R)-2-[(3R)-3-amino-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]-2-oxopyrrolidin-1-yl]-N-hyd. Grades: 98%. CAS No. 611227-74-8. Molecular formula: C27H32N4O4. Mole weight: 476.57. | |
| Boc-(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid | (2S,3S)-1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic acid is a chiral, α-amino acid that is used extensively in organic synthesis due to its intriguing physical and chemical properties. The compound is also known as Boc-D-3-hydroxyproline, Boc-D-Hyp-OH or D-3-Hyp. Uses: The compound can be used for developing novel drug candidates, as a chiral building block in the synthesis of biologically active compounds, and as proline isomers in peptide chemistry and protein applications. studies also show that it can inhibit the activity of protease enzymes and is used in peptide synthesis. Additional or Alternative Names: (2S,3S)-3-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid. Product Category: Amino Acids. CAS No. 187039-57-2. Molecular formula: C10H17NO5. Mole weight: 231.2. Purity: TLC major spot. IUPACName: (2S,3S)-3-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid. Canonical SMILES: CC(C)(C)OC(=O)N1CCC(C1C(=O)O)O. Density: 1.3±0.1 g/cm3. Product ID: ACM187039572-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Boc-cis-3-hydroxy-L-proline | Boc-cis-3-hydroxy-L-proline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-T-BOC-CIS-3-HYDROXY-L-PROLINE;BOC-CIS-3-HYDROXY-L-PROLINE;(1,2-Pyrrolidinedicarboxylicacid, 3-hydroxy-, 1-(1,1-diMethylethyl) ester, (2S,3R)- );(2S,3R)-3-Hydroxy-1,2-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester;(2S,3R)-1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic acid;(2S,3R)-3-Hydroxypyrrolidine-2-carboxylicacid,N-BOCprotected. CAS No. 186132-96-7. Molecular formula: C10H17NO5. Mole weight: 231.25. Purity: 95+%. IUPACName: (2S,3R)-3-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylicacid. Canonical SMILES: CC(C)(C)OC(=O)N1CCC(C1C(=O)O)O. Density: 1.312±0.06 g/cm³ (20 ºC 760 Torr). Product ID: ACM186132967. Alfa Chemistry ISO 9001:2015 Certified. Categories: 186132-80-9. | |
| cis-4-Hydroxy-d-proline methyl ester hydrochloride | cis-4-Hydroxy-d-proline methyl ester hydrochloride. Group: Biochemicals. Alternative Names: (2R,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride; (2R, 4R) -4-Hydroxy-2- (methoxycarbonyl) pyrrolidine hydrochloride. Grades: Highly Purified. CAS No. 114676-59-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences. | Worldwide |
| Delaminomycin C | Delaminomycin C is an extracellular Matrix receptor antagonist and immunomodulator produced by Streptomyces albulus MJ202-72F3. It inhibits cell adhesion ECM (Extracellular matrix), reduces immune response activity, and inhibits Gram-positive bacteria. Synonyms: (3Z)-3-[[2-[(3E,5E)-2,8-dihydroxy-7-methyldeca-3,5-dienyl]-1,6,8-trimethyl-4a,5,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]-hydroxymethylidene]pyrrolidine-2,4-dione; 2H-Imidazol-2-one, 3-((2-(2,8-dihydroxy-7-methyl-3,5-decadienyl)-1,2,4a,5,6,7,8,8a-octahydro-1,6,8-trimethyl-1-naphthalenyl)carbonyl)-1,5-dihydro-4-hydroxy-. CAS No. 149779-40-8. Molecular formula: C29H43NO5. Mole weight: 485.65. | |
| Dermorphin | Dermorphin, a naturally occurring heptapeptide originally found in the skin of amphibians, is a μ-opioid receptor(MOR) agonist with analgesic and antinociceptive effects. Synonyms: H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2; L-tyrosyl-D-alanyl-L-phenylalanyl-glycyl-L-tyrosyl-L-prolyl-L-serinamide; (S)-N-((S)-1-amino-3-hydroxy-1-oxopropan-2-yl)-1-((2S,8S,11R,14S)-14-amino-8-benzyl-2-(4-hydroxybenzyl)-15-(4-hydroxyphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)pyrrolidine-2-carboxamide. Grades: >96%. CAS No. 77614-16-5. Molecular formula: C40H50N8O10. Mole weight: 802.87. | |
| DPP-IV-IN-1 | A potent inhibitor of dipeptidyl peptidase IV (DPP-IV). Synonyms: 2-Pyrrolidinecarbonitrile, 4-fluoro-1-[2-[(2-hydroxy-1,1-dimethylethyl)amino]acetyl]-, (2S,4S)-; (2S,4S)-4-fluoro-1-[2-[(1-hydroxy-2-methylpropan-2-yl)amino]acetyl]pyrrolidine-2-carbonitrile. CAS No. 625110-37-4. Molecular formula: C11H18FN3O2. Mole weight: 243.28. | |
| DT-2216 | DT2216 is a potent and selective Bcl-xL-specific degrader. DT2216 is highly active against Bcl-xL-dependent T cell lymphomas. DT2216 selectively killed various Bcl-xL-dependent TCL cells including MyLa cells in vitro. In vivo, DT2216 alone was highly effective against MyLa TCL xenografts in mice without causing significant thrombocytopenia or other toxicity. Furthermore, DT2216 combined with ABT199 (a selective Bcl-2 inhibitor) synergistically reduced disease burden and improved survival in a TCL PDX mouse model dependent on both Bcl-2 and Bcl-xL. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DT-2216; DT2216; DT 2216; DT2216 HCl. Product Category: Others. Appearance: Solid powder. CAS No. 2365172-42-3. Molecular formula: C77H96ClF3N10O10S4. Mole weight: 1542.36. Purity: >98%. IUPACName: (2S,4R)-1-((S)-2-(7-(4-((R)-3-((4-(N-(4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-((trifluoromethyl)sulfonyl)phenyl)amino)-4-(phenylthio)butyl)piperazin-1-yl)-7-oxoheptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide. Canonical SMILES: CC1(C)CCC(C2=CC=C(Cl)C=C2)=C(C1)CN3CCN(C4=CC=C(C(NS(=O)(C5=CC(S(C(F)(F)F)(=O)=O)=C(N[C@@H](CSC6=CC=CC=C6)CCN7CCN(C(CCCCCC(N[C@@H](C(C)(C)C)C(N8[C@@H](C[C@@H](O)C8)C(N[C@H](C9=CC=C(C%10=C(N=CS%10)C)C=C9)C)=O)=O)=O)=O)CC7)C=C5)=O)=O)C=C4) | |
| EBPC | EBPC is a potent and selective aldose reductase inhibitor. It is used to improve the cytotoxicity of anticancer reagents such as cisplatin and doxorubicin in HeLa cervical carcinoma cells via an increase in ERK activity. Synonyms: Ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate; 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester; MFCD00179167; 1-benzyl-4-[ethoxy (hydroxy)methylidene]pyrrolidine-2, 3-dione. Grades: ≥99% by HPLC. CAS No. 4450-98-0. Molecular formula: C14H15NO4. Mole weight: 261.28. | |
| Epiequisetin | It is a minor isomer of equisetin and a potent inhibitor of HIV-integrase produced by a number of species of Fusarium. It has comparable phytotoxicity to equisetin. Synonyms: 5-Epiequisetin; (3E,5R)-5-(Hydroxymethyl)-3-[hydroxy[(1S,2R,4aS,6R,8aR)-1,2,4a,5,6,7,8,8a-octahydro-1,6-dimethyl-2-(1E)-1-propen-1-yl-1-naphthalenyl]methylene]-1-methyl-2,4-pyrrolidinedione; 3-epi-Equisetin; epi-Equisetin; 5'-epi-Equisetin. Grades: >98% by HPLC. CAS No. 255377-45-8. Molecular formula: C22H31NO4. Mole weight: 373.49. | |
| ERD-308 | ERD-308 is a Highly Potent Proteolysis Targeting Chimera Degrader of Estrogen Receptor (ER) ERD-308 achieves DC50 (concentration causing 50% of protein degradation) values of 0.17 and 0.43 nM in MCF-7 and T47D ER+ breast cancer cell lines, respectively, and induces >95% of ER degradation at concentrations as low as 5 nM in both cell lines. Significantly, ERD-308 induces more complete ER degradation than fulvestrant, the only approved selective ER degrader (SERD), and is more effective in inhibition of cell proliferation than fulvestrant in MCF-7 cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ERD-308; ERD 308; ERD308. Product Category: Others. Appearance: Solid powder. CAS No. 2320561-35-9. Molecular formula: C55H65N5O9S2. Mole weight: 1004.27. Purity: >98%. IUPACName: (2S,4R)-1-((S)-2-(2-((5- (Ethyl(2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)phenoxy)ethyl)-amino)pentyl)oxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide. Canonical SMILES: O=C([C@H]1N(C([C@@H](NC(COCCCCCN(CC)CCOC2=CC=C(C(C3=C(C4=CC=C(O)C=C4)SC5=CC(O)=CC=C53)=O)C=C2)=O)C(C)(C)C)=O)C[C@H](O)C1)N[C@H](C6=CC=C(C7=C(C)N=CS7)C=C6)C. Product ID: ACM2320561359. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fibronectin CS1 Peptide | Fibronectin CS1 Peptide lacks a domain containing Arg-Gly-Asp, and it can effectively inhibit tumor metastasis in both spontaneous and experimental metastatic models. Synonyms: Fibronectin CS-1 Fragment (1978-1985); H-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr-OH; L-alpha-glutamyl-L-isoleucyl-L-leucyl-L-alpha-aspartyl-L-valyl-L-prolyl-L-seryl-L-threonine; (3S,6S,9S,12S,15S)-15-amino-12-sec-butyl-3-((S)-2-((S)-1-((1S,2R)-1-carboxy-2-hydroxypropylamino)-3-hydroxy-1-oxopropan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)-6-(carboxymethyl)-9-isobutyl-2-methyl-5,8,11,14-tetraoxo-4,7,10,13-tetraazaoctadecan-18-oic acid. Grades: ≥95%. CAS No. 136466-51-8. Molecular formula: C38H64N8O15. Mole weight: 872.96. | |
| FK 888 | FK 888 is a potent and selective tachykinin NK1 receptor antagonist (Ki = 0.69 nM) with 320-fold selectivity for human over rat NK1 receptors. It inhibits substance P-induced contraction of isolated guinea pig trachea (IC50 = 32 nM) and inhibits substance P-induced airway constriction in vivo following i.v. and oral administration. Synonyms: FK-888; FK 888; FK888. (4R)-4-Hydroxy-1-[(1-methyl-1H-indol-3-yl)carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-L-alaninamide; (2S,4R)-N-[(2S)-1-[benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-4-hydroxy-1-(1-methylindole-3-carbonyl)pyrrolidine-2-carboxamide. Grades: ≥98% by HPLC. CAS No. 138449-07-7. Molecular formula: C36H36N4O4. Mole weight: 588.69. | |
| Glycopyrrolate Impurity 8 | Glycopyrrolate Impurity 8 is one of Glycopyrrolate impurities. Glycopyrrolate is an anticholinergic agent with antispasmodic activity used to treat gastrointestinal conditions associated. Synonyms: (S)-(+)-1-Methyl-3-pyrrolidinol; (S)-1-Methyl-3-pyrrolidinol; (S)-3-Hydroxy-1-methylpyrrolidine. Grades: 98 %. CAS No. 104641-59-0. Molecular formula: C5H11NO. Mole weight: 101.15. | |
| Harzianic acid | It is produced by the strain of Trichoderma harzianum SY-307. It has the activity against Pasteurella Piscicida SP.6395. Synonyms: 2-Pyrrolidinepropanoic acid, 3,5-dioxo-alpha-hydroxy-4-(1-hydroxy-2,4-octadienylidene)-1-methyl-alpha-(1-methylethyl)-. Grades: ≥98%. CAS No. 157148-06-6. Molecular formula: C19H27NO6. Mole weight: 365.42. | |
| H-Pro-thr-his-ile-lys-trp-gly-asp-oh | H-Pro-thr-his-ile-lys-trp-gly-asp-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-PRO-THR-HIS-ILE-LYS-TRP-GLY-ASP-OH;PRO-THR-HIS-ILE-LYS-TRP-GLY-ASP;tuna AI. Product Category: Heterocyclic Organic Compound. CAS No. 117620-76-5. Molecular formula: C44H64N12O12. Mole weight: 953.0522. Purity: 0.96. IUPACName: (2S)-2-[[2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]-3-(4H-imidazol-4-yl)propanoyl]amino]-3-methylpentanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]acetyl]amino]. Canonical SMILES: CCC(C)C(C(=O)NC(CCCCN)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NCC(=O)NC(CC(=O)O)C(=O)O)NC(=O)C(CC3=CN=CN3)NC(=O)C(C(C)O)NC(=O)C4CCCN4. Density: 1.49 g/cm³. Product ID: ACM117620765. Alfa Chemistry ISO 9001:2015 Certified. | |
| Isohematinic acid | It is produced by the strain of Actinoplanes philippinensis SANK 61681. Isohematinic acid has weak anti-anaerobic bacteria action. Synonyms: (+-)-2,5-Dioxo-4-methylene-3-pyrrolidinepropanoic acid; 3-(5-Hydroxy-4-methylidene-2-oxo-3,4-dihydro-2H-pyrrol-3-yl)propanoic acid. CAS No. 86408-37-9. Molecular formula: C8H9NO4. Mole weight: 183.16. | |
| Lactacystin | Lactacystin is a microbial metabolite isolated from streptomyces. It is a 20S proteasome inhibitor. Synonyms: (2R,3S,4R)-3-Hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-2-pyrrolidinecarboxy-N-acetyl-L-cysteine thioester. Grades: ≥95%. CAS No. 133343-34-7. Molecular formula: C15H24N2O7S. Mole weight: 376.42. | |
| LDV FITC | LDV FITC is a fluorescent ligand. It can bind to the α4β1 integrin (VLA-4) with high affinity. It can be used to detect VLA-4 affinity and conformational changes. Synonyms: LDV FITC; 1207610-07-8; 4- [ [ (5S) -5-Carboxy-5- [ [ (2S) -2- [ [ (2S) -2- [ [ (2S) -1- [ (2S) -2- [ [ (2S) -3-carboxy-2- [ [ (2S) -4-methyl-2- [ [2- [4- [ (2-methylphenyl) carbamoylamino] phenyl] acetyl] amino] pentanoyl] amino] propanoyl] amino] -3-methylbutanoyl] pyrrolidine-2-carbonyl] amino] propanoyl] amino] propanoyl] amino] pentyl] carbamothioylamino] -2- (3-hydroxy-6-oxoxanthen-9-yl) benzoic acid; AKOS025147314; PD079718. Grades: ≥98% by HPLC. CAS No. 1207610-07-8. Molecular formula: C69H81N11O17S. Mole weight: 1368.54. | |
| Leucinostatin D | It is produced by the strain of Paecilomyces marquandii. It's a peptide antibiotic. It has anti-gram-positive bacterial and fungal effects. It has in vitro cytotoxic activity against HeLa 850, KB cells and sensitive leukemia cells P388 with ID50 of 1.00 ng/mL. Synonyms: Paecilotoxin D; (4R) -N- [1- [ [2-hydroxy-3-methyl-1- [2- [ [3-methyl-1- [ [3-methyl-1- [2- [2- [2- (1-methylaminopropan-2-ylcarbamoyl) ethylcarbamoyl] propan-2-ylcarbamoyl] propan-2-ylcarbamoyl] butyl] carbamoyl] butyl] carbamoyl] propan-2-ylcarbamoyl] butyl] carbamoyl] -3-methyl-butyl] -4-methyl-1- [ (E, 4S) -4-methylhex-2-enoyl] pyrrolidine-2-carboxamide. CAS No. 100334-47-2. Molecular formula: C56H101N11O11. Mole weight: 1104.47. | |
| Leucinostatin H | It is produced by the strain of Paecilomyces marquandii. It's a peptide antibiotic. It has anti-gram-positive bacterial and fungal effects. Synonyms: Paecilotoxin H; N-(1-(aminooxy)-26-(1-hydroxy-2-methylpropyl)-17,20-diisobutyl-4,11,11,14,14,23,23,31-octamethyl-6,10,13,16,19,22,25,28-octaoxo-5,9,12,15,18,21,24,27-octaazadotriacontan-29-yl)-4-methyl-1-((R,E)-4-methylhex-2-enoyl)pyrrolidine-2-carboxamide; Leucinostatin A, 2-L-leucine, N9-oxide. CAS No. 109539-58-4. Molecular formula: C57H103N11O12. Mole weight: 1134.49. | |
| Leucinostatin K | It is produced by the strain of Paecilomyces marquandii. It's a peptide antibiotic. It has anti-gram-positive bacterial and fungal effects. Synonyms: Leucinostatin A, N9-oxide; b-Alaninamide, cis-4-methyl-1-(4-methyl-1-oxo-2-hexenyl)-L-prolyl-(4S,6S)-6-hydroxy-4-methyl-8-oxo-L-2-aminodecanoyl-threo-3-hydroxy-L-leucyl-2-methylalanyl-L-leucyl-L-leucyl-2-methylalanyl-2-methylalanyl-N-[2-(dimethylamino)-1-methylethyl]-, N9-oxide, [1[S-(E)],9(S)]-; N-(1-(aminooxy)-33-hydroxy-26-(1-hydroxy-2-methylpropyl)-17,20-diisobutyl-4,11,11,14,14,23,23,31-octamethyl-6,10,13,16,19,22,25,28,35-nonaoxo-5,9,12,15,18,21,24,27-octaazaheptatriacontan-29-yl)-4-methyl-1-((R,E)-4-methylhex-2-enoyl)pyrrolidine-2-carboxamide. CAS No. 109539-57-3. Molecular formula: C62H111N11O14. Mole weight: 1234.61. | |
| Leuprolide Acetate EP Impurity E | Leuprolide Acetate EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Leuprolide Acetate EP Impurity E, 1-9-Luteinizing hormone-releasing factor (swine), 3-D-tryptophan-6-D-leucine-9-(N-ethyl-L-prolinamide)-,L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-D-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-. CAS No. 1926163-23-6. IUPAC Name: (2S)-N-[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide. Molecular Formula: C59H84N16O12. Mole Weight: 1209.40. Catalog: APS1926163236. SMILES: CCNC (=O)[C@@H]1CCCN1C (=O)[C@H] (CCCNC (=N)N)NC (=O)[C@H] (CC (C)C)NC (=O)[C@@H] (CC (C)C)NC (=O)[C@H] (Cc2ccc (O)cc2)NC (=O)[C@H] (CO)NC (=O)[C@@H] (Cc3c[nH]c4ccccc34)NC (=O)[C@H] (Cc5c[nH]cn5)NC (=O)[C@@H]6CCC (=O)N6. Format: Neat. | |
| Leuprolide Acetate EP Impurity F | Leuprolide Acetate EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: L-Prolinamide, 5-oxo-L-prolyl-D-histidyl-L-tryptophyl-D-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-, Leuprolide Acetate EP Impurity F. CAS No. 1872435-00-1. IUPAC Name: (2S)-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide. Molecular Formula: C59H84N16O12. Mole Weight: 1209.40. Catalog: APS1872435001. SMILES: CCNC (=O)[C@@H]1CCCN1C (=O)[C@H] (CCCNC (=N)N)NC (=O)[C@H] (CC (C)C)NC (=O)[C@@H] (CC (C)C)NC (=O)[C@H] (Cc2ccc (O)cc2)NC (=O)[C@@H] (CO)NC (=O)[C@H] (Cc3c[nH]c4ccccc34)NC (=O)[C@@H] (Cc5c[nH]cn5)NC (=O)[C@@H]6CCC (=O)N6. Format: Neat. | |
| Leuprolide Acetate EP Impurity H | Leuprolide Acetate EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Leuprolide Acetate EP Impurity H,Luteinizing hormone-releasing factor (swine), 6-D-leucine-7-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide- (9CI), Luteinizing hormone-releasing factor (pig), 6-D-leucine-7-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-. CAS No. 112710-58-4. IUPAC Name: (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2S)-5-carbamimidamido-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide. Molecular Formula: C59H84N16O12. Mole Weight: 1209.40. Catalog: APS112710584. SMILES: CCNC (=O)[C@@H]1CCCN1C (=O)[C@H] (CCCNC (=N)N)NC (=O)[C@@H] (CC (C)C)NC (=O)[C@@H] (CC (C)C)NC (=O)[C@H] (Cc2ccc (O)cc2)NC (=O)[C@H] (CO)NC (=O)[C@H] (Cc3c[nH]c4ccccc34)NC (=O)[C@H] (Cc5c[nH]cn5)NC (=O)[C@@H]6CCC (=O)N6. Format: Neat. | |
| L-Isoleucine,l-tyrosyl-L-prolyl-L-phenylalanyl-L-valyl-L-a-glutamyl-L-prolyl- | L-Isoleucine,l-tyrosyl-L-prolyl-L-phenylalanyl-L-valyl-L-a-glutamyl-L-prolyl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: beta-Casomorphin, beta-Casomorphin human, C0783_SIGMA, MolPort-003-940-605, CID4424653, CID 9832595, 102029-74-3. Product Category: Heterocyclic Organic Compound. CAS No. 102029-74-3. Molecular formula: C44H61N7O11. Mole weight: 864. Purity: 0.96. IUPACName: 2-[[1-[2-[[2-[[2-[[1-[2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-5-hydroxy-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-3-methylpentanoic acid. Canonical SMILES: CCC(C)C(C(=O)O)NC(=O)C1CCCN1C(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C(CC2=CC=CC=C2)NC(=O)C3CCCN3C(=O)C(CC4=CC=C(C=C4)O)N. Density: 1.299 g/cm³. Product ID: ACM102029743. Alfa Chemistry ISO 9001:2015 Certified. Categories: H-Tyr-Pro-Phe-Val-Glu-Pro-Ile-OH. | |
| N-α-(t-Butoxycarbonyl)-cis-4-hydroxy-D-proline | Synonyms: Boc-D-cis-Hyp-OH; (2R,4R)-1-(t-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid; Boc-Cis-4-Hydroxy-D-Proline; N-Boc-cis-4-Hydroxy-D-proline; (2R,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid; (2R,4R)-N-Boc-4-hydroxy-2-pyrrolidinecarboxylic acid; Boc-(2R,4R)-(+)-4-hydroxypyrrolidine-2-carboxylic acid. Grades: ≥ 98%. CAS No. 135042-12-5. Molecular formula: C10H17NO5. Mole weight: 231.25. | |
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