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| Product | Description | |
|---|---|---|
| Iron Amino Acid Chelate 20% | Iron Amino Acid Chelate 20%. |  CA, FL & NJ |
| iron-chelate-transporting ATPase | ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. A bacterial enzyme that imports Fe-enterobactin, Fe-dicitrate, Fe-hydroxamate and other siderophores. Group: Enzymes. Enzyme Commission Number: EC 3.6.3.34. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4672; iron-chelate-transporting ATPase; EC 3.6.3.34. Cat No: EXWM-4672. |  |
| Deferasirox Fe3(addition) chelate | Deferasirox Fe3+ chelate is a rationally-designed oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias. Synonyms: Exjade Fe3+ chelate. Grades: >98%. CAS No. 554435-83-5. Molecular formula: C21H12FeN3O4. Mole weight: 426.18. |  |
| EDDHSA | EDDHSA is an analog of EDDHA (E335100) and is used to form the iron chelate EDDHSA/Fe3+, which is used as a soil fertilizer to treat iron chlorosis in plants growing in calcareous soils. Group: Biochemicals. Grades: Highly Purified. CAS No. 57368-07-7. Pack Sizes: 10mg, 100mg. Molecular Formula: C18H20N2O12S2. US Biological Life Sciences. |  Worldwide |
| EDTA disodium | EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ethylenediaminetetraacetic acid disodium. CAS No. 139-33-3. Pack Sizes: 10 g; 25 g. Product ID: HY-W018746. |  |
| ferric-chelate reductase (NADH) | Contains FAD. The enzyme catalyses the reduction of bound ferric iron in a variety of iron chelators (siderophores), resulting in the release of ferrous iron. The plant enzyme is involved in the transport of iron across plant plasma membranes. The enzyme from the bacterium Paracoccus denitrificans can also reduce chromate. cf. EC 1.16.1.9, ferric-chelate reductase (NADPH) and EC 1.16.1.10, ferric-chelate reductase [NAD(P)H]. Group: Enzymes. Synonyms: ferric chelate reductase (ambiguous); iron chelate reductase (ambiguous); NADH:Fe3+-EDTA reductase; NADH2:Fe3+ oxidoreductase; ferB (gene name); Fe(II):NAD+ oxidoreductase. Enzyme Commission Number: EC 1.16.1.7. CAS No. 120720-17-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1072; ferric-chelate reductase (NADH); EC 1.16.1.7; 120720-17-4; ferric chelate reductase (ambiguous); iron chelate reductase (ambiguous); NADH:Fe3+-EDTA reductase; NADH2:Fe3+ oxidoreductase; ferB (gene name); Fe(II):NAD+ oxidoreductase. Cat No: EXWM-1072. | |
| ferric-chelate reductase (NADPH) | Contains FAD. The enzyme, which is widespread among bacteria, catalyses the reduction of ferric iron bound to a variety of iron chelators (siderophores), including ferric triscatecholates and ferric dicitrate, resulting in the release of ferrous iron. The enzyme from the bacterium Escherichia coli has the highest efficiency with the hydrolysed ferric enterobactin complex ferric N-(2,3-dihydroxybenzoyl)-L-serine. cf. EC 1.16.1.7, ferric-chelate reductase (NADH) and EC 1.16.1.10, ferric-chelate reductase [NAD(P)H]. Group: Enzymes. Synonyms: ferric chelate reductase (ambiguous); iron chelate reductase (ambiguous); NADPH:Fe3+-EDTA reductase; NADPH-dependent ferric reductase; yqjH (gene name); Fe(II):NADP+ oxidoreductase. Enzyme Commission Number: EC 1.16.1.9. CAS No. 120720-17-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1074; ferric-chelate reductase (NADPH); EC 1.16.1.9; 120720-17-4; ferric chelate reductase (ambiguous); iron chelate reductase (ambiguous); NADPH:Fe3+-EDTA reductase; NADPH-dependent ferric reductase; yqjH (gene name); Fe(II):NADP+ oxidoreductase. Cat No: EXWM-1074. | |
| ferric-chelate reductase [NAD(P)H] | A flavoprotein. The enzyme catalyses the reduction of bound ferric iron in a variety of iron chelators (siderophores), resulting in the release of ferrous iron. The enzyme from the hyperthermophilic archaeon Archaeoglobus fulgidus is not active with uncomplexed Fe(III). cf. EC 1.16.1.7, ferric-chelate reductase (NADH) and EC 1.16.1.9, ferric-chelate reductase (NADPH). Group: Enzymes. Synonyms: ferric reductase (ambiguous). Enzyme Commission Number: EC 1.16.1.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1066; ferric-chelate reductase [NAD(P)H]; EC 1.16.1.10; ferric reductase (ambiguous). Cat No: EXWM-1066. | |
| manganese-transporting ATPase | ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. A bacterial enzyme that imports Mn2+, Zn2+ and iron chelates. Group: Enzymes. Synonyms: ABC-type manganese permease complex. Enzyme Commission Number: EC 7.2.2.5 (Formerly EC 3.6.3.35). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4673; manganese-transporting ATPase; EC 3.6.3.35; ABC-type manganese permease complex. Cat No: EXWM-4673. | |
| nicotianamine aminotransferase | A pyridoxal-phosphate protein. This enzyme is produced by grasses. They secrete both the nicotianamine and the transaminated product into the soil around them. Both compounds chelate iron(II) and iron(III); these chelators, called mugineic acid family phytosiderophores, are taken up by the grass, which is thereby supplied with iron. Group: Enzymes. Synonyms: NAAT; NAAT-I; NAAT-II; NAAT-III; nicotianamine transaminase. Enzyme Commission Number: EC 2.6.1.80. CAS No. 154907-64-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2921; nicotianamine aminotransferase; EC 2.6.1.80; 154907-64-9; NAAT; NAAT-I; NAAT-II; NAAT-III; nicotianamine transaminase. Cat No: EXWM-2921. | |
| Phytic acid (50% in water) | Phytic acid (Inositol hexaphosphate) (50% in water) is a phosphorus storage compound of seeds and cereal grains. Phytic acid (50% in water) is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid (50% in water) inhibits the enzymatic superoxide source xanthine oxidase (XO) , and has antioxidative, neuroprotective, anti-inflammatory effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Inositol hexaphosphate; SNF472 free acid. CAS No. 83-86-3. Pack Sizes: 250 mg (757.5 mM * 500 μL in Water). Product ID: HY-N0814. | |
| Phytic acid dodecasodium hydrate | Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO) , and has antioxidative, neuroprotective, anti-inflammatory effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Inositol hexaphosphate dodecasodium hydrate; SNF472 dodecasodium hydrate. CAS No. 123408-98-0. Pack Sizes: 250 mg. Product ID: HY-N0814A. | |
| pulcherriminic acid synthase | A heme-thiolate (P-450) enzyme from the bacterium Bacillus subtilis. The order of events during the overall reaction is unknown. Pulcherrimic acid spontaneously forms an iron chelate with Fe(3+) to form the red pigment pulcherrimin. Group: Enzymes. Synonyms: cyclo-L-leucyl-L-leucyl dipeptide oxidase; CYP134A1; CypX (ambiguous). Enzyme Commission Number: EC 1.14.15.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0938; pulcherriminic acid synthase; EC 1.14.15.13; cyclo-L-leucyl-L-leucyl dipeptide oxidase; CYP134A1; CypX (ambiguous). Cat No: EXWM-0938. | |
| (1,2-Cyclohexylenedinitrilo)tetraacetic Acid, Reagent | (1,2-Cyclohexylenedinitrilo)tetraacetic Acid, Reagent. Synonyms: trans-1,2-Diaminocyclohexane-N,N,N',N'-tetracetic acid monohydrate, 1,2-Cyclohexanediamine-N,N,N'N'-tetraacetic acid, 1,2-Cyclohexylenedinitrilotetraacetic acid, 1,2-Diaminocyclohexane-N,N,N',N'-tetraacetic acid. CAS No. 125572-95-4. Pack Sizes: 25, 100 g in Glass bottle. Product ID: CDC10-0090. Molecular formula: C14H22N2O8·xH2O. Category: Cosmetic Chelating Chemicals. Product Keywords: Cosmetic Ingredients; Cosmetic Chelating Chemicals; (1,2-Cyclohexylenedinitrilo)tetraacetic Acid, Reagent; CDC10-0090; 125572-95-4; C14H22N2O8·xH2O; trans-1,2-Diaminocyclohexane-N,N,N',N'-tetracetic acid monohydrate, 1,2-Cyclohexanediamine-N,N,N'N'-tetraacetic acid, 1,2-Cyclohexylenedinitrilotetraacetic acid, 1,2-Diaminocyclohexane-N,N,N',N'-tetraacetic acid; 681-197-6; MFCD00149243; 125572-95-4. Purity: 0.99. Color: White. EC Number: 681-197-6. Physical State: Powder. Solubility: Slightly soluble in water. Soluble in 1N sodium hydroxide and alkali solutions. Insoluble in most common organic solvents. Quality Level: 200. Storage: 2-30°C. Application: trans-1,2-Diaminocyclohexane-N,N,N',N'-tetraacetic acid monohydrate is an analytical reagent and a complexating agent for sodium. It acts as a ligand to prepare lanthanide shift reagents. It is involved in the separation and determination of iron(III)-dimethyldithiocarbamate, manganes |  |
| 1, 2-Diisonicotinoyl hydrazine | 1, 2-Diisonicotinoyl hydrazine is an iron chelator. Group: Biochemicals. Grades: Highly Purified. CAS No. 4329-75-3. Pack Sizes: 250mg, 1g. Molecular Formula: C12H10N4O2. US Biological Life Sciences. | Worldwide |
| 1, 2-Diisonicotinoyl hydrazine-d8 | 1, 2-Diisonicotinoyl hydrazine-d8 is the labeled analogue of 1, 2-Diisonicotinoyl hydrazine (D455275) is an iron chelator. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C12H2D8N4O2, Molecular Weight: 250.28. US Biological Life Sciences. | Worldwide |
| 2,2'-(Thiobis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one) | 2,2'-(Thiobis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one) is an impurity compound of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 2,2'-(THIOBIS(2-HYDROXY-5,1-PHENYLENE))BISONE). CAS No. 1688656-86-1. Molecular formula: C28H16N2O6S. Mole weight: 508.50. | |
| 2-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid | 2-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: Deferasirox 1,2-isomer; Deferasirox Impurity C. CAS No. 201530-78-1. Molecular formula: C21H15N3O4. Mole weight: 373.36. | |
| 2-Deoxymugineic Acid | Phytosiderophores are produced in higher plants as iron chelating amino acids that promote uptake of iron from soil. Group: Biochemicals. Alternative Names: (αS,2S)-2-Carboxy-α-[[(3S)-3-carboxy-3-hydroxypropyl]amino]-1-azetidinebutanoic Acid; 2'-Dehydroxymugineic Acid; DMA. Grades: Highly Purified. CAS No. 74235-24-8. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| 2-(Hydroxyphenyl)-4H-1,3-benzoxazin-4-one | 2-(Hydroxyphenyl)-4H-1,3-benzoxazin-4-one is an impurity of Deferasirox (D228650), orally active tridentate iron chelator. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C21H13NO5, Molecular Weight: 359.33. US Biological Life Sciences. | Worldwide |
| 2-Picolinic acid | Picolinic acid is a metabolite of tryptophan that acts as an anti-infective and immunomodulator. It is produced under inflammatory conditions. Uses: Iron chelating agents. Synonyms: pyridine-2-carboxylic acid. Grades: 95 %. CAS No. 98-98-6. Molecular formula: C6H5NO2. Mole weight: 123.11. | |
| 3-Benzotriazol-1-yl-propionic Acid | 3-Benzotriazol-1-yl-propionic Acid is used in biological studies of azole derivatives as a novel non-iron-chelating inhibitors of prolyl hydroxylase 3 for HIF-1 activation. Group: Biochemicals. Grades: Highly Purified. CAS No. 654-15-9. Pack Sizes: 250mg, 1g. Molecular Formula: C9H9N3O2, Molecular Weight: 191.19. US Biological Life Sciences. | Worldwide |
| 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone | A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transferrin and ferritin in vitro. Synonyms: 3-hydroxy-1,2-dimethylpyridin-4-one. Grades: 99 %. CAS No. 30652-11-0. Molecular formula: C7H9NO2. Mole weight: 139.15. | |
| 3-Hydroxy-2-(5-hydroxypentyl)chromen-4-one (IC2) | An iron tridentate chelator which inactivates the iron redox cycle after is complexation. Group: Biochemicals. Alternative Names: IC2. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 3-Hydroxy Deferasirox | 3-Hydroxy Deferasirox is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 4-[3-(2,3-Dihydroxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid; 4-[3-(2,3-Dihydroxyphenyl)-5-(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]-benzoic Acid; Metabolite M2. CAS No. 524746-11-0. Molecular formula: C21H15N3O5. Mole weight: 389.36. | |
| 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-1-methylethyl ester benzoic acid | 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-1-methylethyl ester benzoic acid is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: Deferasirox Isopropyl ester. CAS No. 1266741-29-0. Molecular formula: C24H21N3O4. Mole weight: 415.44. | |
| 4-Hydrazinobenzoic Acid | 4-Hydrazinobenzoic Acid can be used for the synthesis of Deferasirox, which is an orally active tridentate iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: (4-Carboxyphenyl)hydrazine; (p-Carboxyphenyl)hydrazine; NSC 3813; p-Hydrazinobenzoic Acid; 4-Hydrazinylbenzoic Acid. Grades: 95%. CAS No. 619-67-0. Molecular formula: C7H8N2O2. Mole weight: 152.15. | |
| 4- (N-Boc-aminoxyacetamido) benzyl Ethylene diaminetetraacetic Acid, Tetra(t-butyl) Ester | A Boc protected bifunctional iron chelating agent that has be. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 5-Hydroxy Deferasirox(Metabolite M1) | 5-Hydroxy Deferasirox is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 4-[3-(2,5-Dihydroxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid. CAS No. 524746-12-1. Molecular formula: C21H15N3O5. Mole weight: 389.36. | |
| 5'-Hydroxy Deferasirox(Metabolite M4) | 5'-Hydroxy Deferasirox is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 4-[5-(2,5-Dihydroxyphenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid. CAS No. 524746-13-2. Molecular formula: C21H15N3O5. Mole weight: 389.36. | |
| 5-Methoxycarbonyl Deferasirox | 5-Methoxycarbonyl Deferasirox is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 3-[1-(4-Carboxyphenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-5-yl]-4-hydroxybenzoic Acid 1-Methyl Ester. CAS No. 1395346-29-8. Molecular formula: C23H17N3O6. Mole weight: 431.40. | |
| 5-Sulfosalicilic acid Dihydrate | Used in detection of iron and as a spray reagent to detect amino acids on TLC plate. Poly-functional metal chelating ligand that may be used to form metal coordination complexes. Reducing and fixation of proteins in agarose and polyacrylamide gels. Group: Biochemicals. Alternative Names: 2-Hydroxy-5-sulfobenzoic acid dihydrate. Grades: ACS Grade. CAS No. 5965-83-3. Pack Sizes: 500g, 1Kg, 5Kg. Molecular Formula: C?H??O?S, Molecular Weight: 254.21. US Biological Life Sciences. | Worldwide |
| aerobactin synthase | Requires Mg2+. Aerobactin is one of a group of high-affinity iron chelators known as siderophores and is produced under conditions of iron deprivation. It is a dihydroxamate comprising two molecules of N6-acetyl-N6-hydroxy-L-lysine and one molecule of citric acid. This enzyme catalyses the second of two synthase reactions to link N6-acetyl-N6-hydroxy-L-lysine and citrate. Group: Enzymes. Synonyms: iucC (gene name). Enzyme Commission Number: EC 6.3.2.39. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5756; aerobactin synthase; EC 6.3.2.39; iucC (gene name). Cat No: EXWM-5756. | |
| Aloin-A | Aloin (Aloin-A; Barbaloin-A) is a natural anti-tumor anthraquinone glycoside with iron chelating activity. Aloin induces the differentiation of MC3T3-E1 cells into osteoblasts through MAPK-mediated Wnt and Bmp signaling pathways. Alkaline phosphatase (ALP) is an early marker of osteoblast differentiation, and the activity of ALP is also enhanced by Aloin. Aloin also reduces brain edema, reduces blood-brain barrier disruption and improves cortical impact injuries. Aloin is used in research into osteoporosis and traumatic brain injury (TBI) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Barbaloin-A. CAS No. 1415-73-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0123. | |
| CGP-75254A | CGP-75254A, a novel oral iron chelator, across Caco-2 cells in an attempt to model intestinal epithelial cell permeability in man. Studies predicted that absorption of CGP-75254A is likely to be virtually complete at pH values between 5.5 and 7.0. However, at pH 8.0 permeability is predicted as negligible. Synonyms: sodium;2-[2-[(2-ethoxy-2-oxoethyl)-[(2-hydroxyphenyl)methyl]amino]ethyl-[(2-hydroxyphenyl)methyl]amino]acetate; CGP-75254A; CGP 75254A; CGP75254A; UNII-94KC20I6YX; 199485-27-3 (CGP-75254A Free Acid). Grades: >98%. CAS No. 199485-26-2. Molecular formula: C22H27N2NaO6. Mole weight: 438.45. | |
| Chlorphenamine Impurity B (2,2'-Dipyridylamine) | A metal-complexing agent; an effective iron chelating agent to help protect against UVB radiation. An impurity of Chlorpheniramine Maleate. Synonyms: 2,2'-Iminodipyridine; 2,2'-Bipyridylamine; 2,2'-Iminodipyridine; 2-(2-Pyridylamino)pyridine; Bis(2-pyridyl)amine; Bis(o-pyridyl)amine; Bis(pyridin-2-yl)amine; Di-2-pyridylamine; Di-α-pyridylamine; Dipyridin-2-ylamine; N-(2-Pyridinyl)-2-pyridinamine; NSC 7. Grades: > 95%. CAS No. 1202-34-2. Molecular formula: C10H9N3. Mole weight: 171.2. | |
| Ciclopirox ethanolamine | Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator. Uses: Antifungal agents. Synonyms: Ciclopirox olamine; 41621-49-2; Ciclopirox ethanolamine; ciclopiroxolamine; Batrafen; Micoxolamina; Brumixol; Mycoster; Ciclopiroxolamin; Ciclochem; Dafnegin; Ciclopirox (olamine); HOE 296; Ciclopirox ethanolamine salt (1:1); HOE-296; UNII-50MD4SB4AP; EINECS 255-464-9; 50MD4SB4AP; NSC 336278; NSC-336278; DTXSID6045583; RV4104A; MFCD00078997; 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone ethanolamine salt; Ciclobirox Olamine; 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one compound with 2-aminoethanol (1:1); MLS003170863; 2-aminoethanol; 6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one. Grades: >98%. CAS No. 41621-49-2. Molecular formula: C12H17NO2.C2H7NO. Mole weight: 268.35. | |
| CM1 | CM1 is an orally active iron chelator with high selectivity for iron(III). It can penetrate hepatocytes. CM1 is potentially used for patients with thalassaemia related iron overload and exhibits an inhibitory effect on the growth of Plasmodium falciparum (malaria parrasite; IC50 value 35 μM). Uses: The treatment of thalassaemia related iron overload. Synonyms: CM-1; CM 1; 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one. Grades: 99%. CAS No. 1643659-63-5. Molecular formula: C14H22N2O3. Mole weight: 266.34. | |
| Deferasirox | Deferasirox (ICL 670) is an orally available iron chelator used for the management of transfusional iron overload [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICL 670. CAS No. 201530-41-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17359. | |
| Deferasirox | Orally active tridentate iron chelator. Group: Biochemicals. Alternative Names: 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid; Exjade; ICL-670; ICL-670A; CGP-72670. Grades: Highly Purified. CAS No. 201530-41-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Deferasirox 2-Glucuronide | Deferasirox 2-Glucuronide is a metabolite of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 2-[1-(4-carboxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-3-yl]phenyl β-D-Glucopyranosiduronic acid; β-D-Glucopyranosiduronic acid, 2-[1-(4-carboxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-3-yl]phenyl; Benzoic acid, 4-[3-[2-(β-D-glucopyranuronosyloxy)phenyl]-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-. Grades: >98%. CAS No. 1233196-92-3. Molecular formula: C27H23N3O11. Mole weight: 565.48. | |
| Deferasirox-d4 | Deferasirox-d4 is the deuterium labeled Deferasirox. Deferasirox (ICL 670) is an orally available iron chelator used for the management of transfusional iron overload. Group: Inhibitors. Alternative Names: 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid-d4; Exjade-d4; ICL-670-d4; ICL-670A-d4; CGP-72670-d4. CAS No. 1133425-75-8. Molecular formula: C21H11D4N3O4. Mole weight: 377.39. Appearance: Yellow Solid. Canonical SMILES: OC1=C (C=CC=C1)C2=NC (C3=C (C=CC=C3)O)=NN2C4=C ([2H])C ([2H])=C (C ([2H])=C4[2H])C (O)=O. Catalog: ACM1133425758. |  |
| Deferasirox-d4 | Labeled orally active tridentate iron chelator. Group: Biochemicals. Alternative Names: 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid-d4; Exjade-d4; ICL-670-d4; ICL-670A-d4; CGP-72670-d4. Grades: Highly Purified. CAS No. 1133425-75-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Deferasirox-d4 (Mixture of 6-hydroxyphenyl-d4 isomers) | Labeled orally active tridentate iron chelator. Group: Biochemicals. Alternative Names: 4-[5-(2-Hydroxyphenyl)-3-(6-hydroxyphenyl-2,3,4,5-d4)-1H-1,2,4-triazol-1-yl]benzoic Acid & 4-[3-(2-hydroxyphenyl)-5-(6-hydroxyphenyl-2,3,4,5-d4)-1H-1,2,4-triazol-1-yl]benzoic Acid (1:1). Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Deferasirox Impurity 10 | Deferasirox Impurity 10 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C14H12N2O4. Mole weight: 272.26. | |
| Deferasirox Impurity 12 | Deferasirox Impurity 12 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C21H15N3O4. Mole weight: 373.36. | |
| Deferasirox Impurity 15 | Deferasirox Impurity 15 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C21H15N3O5. Mole weight: 389.36. | |
| Deferasirox Impurity 16 | Deferasirox Impurity 16 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C21H15N3O5. Mole weight: 389.26. | |
| Deferasirox Impurity 17 | Deferasirox Impurity 17 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C28H16N2O6S. Mole weight: 508.50. | |
| Deferasirox Impurity 18 | Deferasirox Impurity E is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: Deferasirox Impurity E. CAS No. 1688656-83-8. Molecular formula: C42H28N6O8S. Mole weight: 776.77. | |
| Deferasirox Impurity 19 (Mixture of Isomers) | Deferasirox Impurity 19 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C42H28N6O9S. Mole weight: 792.77. | |
| Deferasirox Impurity 20 | Deferasirox Impurity 20 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C42H28N6O9S. Mole weight: 792.77. | |
| Deferasirox Impurity 4 | Deferasirox Impurity 4 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C14H11NO4. Mole weight: 257.24. | |
| Deferasirox Impurity 5 | Deferasirox Impurity 5 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C21H15NO5. Mole weight: 361.35. | |
| Deferasirox Impurity 6 | Deferasirox Impurity 6 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C16H15NO4. Mole weight: 285.29. | |
| Deferasirox Impurity 7 | Deferasirox Impurity 7 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Molecular formula: C16H15NO4. Mole weight: 285.29. | |
| Deferasirox Impurity 9 | Deferasirox Impurity 9 is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 3-(3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic acid; Deferasirox 1,3-isomer; Benoic Acid. Molecular formula: C21H15N3O4. Mole weight: 373.36. | |
| Deferasirox Impurity D | Deferasirox Impurity D is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 3-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid; Deferasirox Impurity 9. Grades: >98%. Molecular formula: C21H15N3O4. Mole weight: 373.36. | |
| Deferasirox Impurity F | Deferasirox Impurity F is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: Deferasirox sulfoxide dimer. CAS No. 1688656-84-9. Molecular formula: C42H28N6O9S. Mole weight: 792.77. | |
| Deferasirox impurity G | Deferasirox Impurity G is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 6H-tribenzo[b, f, j][1, 5, 9]trioxacyclododecine-6, 12, 18-triimine. Molecular formula: C21H15N3O3. Mole weight: 357.36. | |
| Deferasirox Meta Isomer | Deferasirox Meta Isomer is an impurity compound of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 3-(3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic Acid; 3-(3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl). CAS No. 2254105-61-6. Molecular formula: C21H15N3O4. Mole weight: 373.36. | |
| Deferasirox Salicyloyl Ester | Deferasirox Saalicyloyl Ester is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 2-Hydroxybenzoic Acid 2-[1-(4-Carboxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-3-yl]phenyl Ester. CAS No. 1395346-28-7. Molecular formula: C28H19N3O6. Mole weight: 493.47. | |
| Deferiprone | Deferiprone is a potent, orally active, brain-penetrant, cell-penetrant, skin-permeable, free iron chelating agent. Deferiprone inhibits the proliferation and migration, and stimulates apoptosis in tumor cell. Deferiprone has antianemic, neuroprotective, anti-inflammatory, antioxidant, and antidotal activity. Deferiprone can be used in cancer, cardiovascular disease, infection, inflammation, and neurological disease study [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. CAS No. 30652-11-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0568. | |
| Deferiprone 3-O-b-D-glucuronide | Deferiprone 3-O-b-D-glucuronide is a biomedicine used in the treatment of iron overload disorders, such as thalassemia and sickle cell anemia. It acts as an iron chelator helping to remove excess iron from the body. Its effectiveness in reducing iron levels has been studied extensively and it holds promise in improving overall patient health. Synonyms: Deferiprone 3-O-beta-D-Glucuronide; CP 20 3-glucuronide; CP 20 3-o-glucuronide; beta-D-Glucopyranosiduronic acid, 1,4-dihydro-1,2-dimethyl-4-oxo-3-pyridinyl; (2S,3S,4S,5R,6S)-6-(1,2-dimethyl-4-oxopyridin-3-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acid; Discontinued See D474011; Deferiprone 3-O-?-D-Glucuronide. CAS No. 141675-48-1. Molecular formula: C13H17NO8. Mole weight: 315.28. | |
| Deferoxamine | Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19 [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Deferoxamine B; Deferriferrioxamine B; Deferrioxamine. CAS No. 70-51-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-B1625. | |
| Deferoxamine mesylate | Deferoxamine mesylate (Deferoxamine B mesylate) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine mesylate upregulates HIF-1α levels with good antioxidant activity. Deferoxamine mesylate also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine mesylate can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19 [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Desferrioxamine B mesylate; DFOM. CAS No. 138-14-7. Pack Sizes: 20 mg; 100 mg; 500 mg. Product ID: HY-B0988. | |
| Deferoxamine Mesylate (NSC 644468) | An iron chelator used for the treatment of acute iron intoxication and of chronic iron overload due to transfusion-dependent anemias. Has been shown to have anti-proliferative effects on vascular smooth muscle cells in vitro and in vivo and to arrest cells in the G1 phase. Induces apoptosis in HL-60 cells by chelating iron. In addition, it has been shown to have antioxidant properties and to protect cells against H?O?-induced damage. Group: Biochemicals. Alternative Names: N1- (5-aminopentyl) -N1-hydroxy-N4- [5- [ [4- [ [5- (acetylhydroxyamino) pentyl] amino] -1, 4-dioxobutyl] hydroxyamino] pentyl] butanediamide Methanesulfonate; N- [5- [3- [ (5-aminopentyl) hydroxycarbamoyl] propionamido] pentyl] -3- [ [5- (N-hydroxyacetamido) pentyl] carbamoyl] propionohydroxamic Acid Methanesulfonate; Ba 33112; DFOM; DFX mesylate; Deferoxamine B mesylate; Deferoxamine methanesulfonate; Deferrioxamine B methanesulfonate; Desferal mesylate; Desferrioxamine B mesylate; Desferrioxamine methanesulfonate; NSC 644468. Grades: Highly Purified. CAS No. 138-14-7. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C??H??N?O?·CH?O?S, Molecular Weight: 656.79. US Biological Life Sciences. | Worldwide |
| Deferoxamine (mesylate) (Standard) | Deferoxamine (mesylate) (Standard) is the analytical standard of Deferoxamine (mesylate). This product is intended for research and analytical applications. Deferoxamine mesylate (Deferoxamine B mesylate) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine mesylate upregulates HIF-1α levels with good antioxidant activity. Deferoxamine mesylate also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine mesylate can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19 [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 138-14-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0988R. | |
| Desferioxamine mesylate | Deferoxamine mesylate, an iron chelator, could be used in the treatment of acute iron poisoning, sickle cell diseases and it is also found to have some extent of antioxidant effects. Uses: Deferoxamine mesylate is an iron chelator that could be used in the treatment of acute iron poisoning, sickle cell diseases and it is also found to have some extent of antioxidant effects. Synonyms: Desferioxamine mesylate. Grades: 95%. CAS No. 138-14-7. Molecular formula: C26H52N6O11S. Mole weight: 656.79. | |
| Dexrazoxane | Dexrazoxane, as an intracellular iron chelating agent, reduces the formation of superoxide radicals and has cardioprotective, anti-inflammatory, antioxidant, anti-tumor and neuroprotective activities. Dexrazoxane inhibits ferroptosis of H9c2 cells by inhibiting HMGB1. Dexrazoxane induces DNA damage and apoptosis in human fibrosarcoma cells [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICRF-187; ADR-529; NSC-169780. CAS No. 24584-09-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0581. | |
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