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10mg Pack Size. Group: Amino Acids, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C10H15NO4. CAS No. 487-79-6. Prepack ID 58606205-10mg. Molecular Weight 213.23. See USA prepack pricing.
Kainicacid
50mg Pack Size. Group: Amino Acids, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C10H15NO4. CAS No. 487-79-6. Prepack ID 58606205-50mg. Molecular Weight 213.23. See USA prepack pricing.
Kainicacid
Kainicacid. Group: Biochemicals. Grades: Purified. CAS No. 487-79-6. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
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Kainicacid
Kainicacid is a naturally occurring neuroexcitatory amino acid. It is a selective agonist for a subtype of ainate-class ionotropic glutamate receptor found in seaweed. It increases production of mitochondrial dysfunction, reactive oxygen species and apoptosis in neurons in many regions of the brain. It increases glutamate release and stimulates Na channels, inducing epileptic seizures and neurocytosis (apoptosis). It has been used to study mechanisms of apoptosis and epilepsy. Uses: Excitatory amino acid agonists. Synonyms: (2S,3S,4S)-3-(carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid; 2-Carboxy-3-carboxymethyl-4-isopropenylpyrrolidine; (-)-α-KainicAcid; Digenic Acid; Digenin; Helminal; L-α-KainicAcid; α-KainicAcid. Grades: ≥98% by HPLC. CAS No. 487-79-6. Molecular formula: C10H15NO4. Mole weight: 213.23.
Kainicacid
Kainicacid is a potent excitotoxic agent. Kainicacid hydrate also is an agonist for a subtype of ionotropic glutamate receptor. Kainicacid induces seizures [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 487-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2309.
Kainicacid
Kainicacid. Uses: For analytical and research use. Group: Impurity standards. CAS No. 487-79-6. Molecular Formula: C10H15NO4. Mole Weight: 213.23. Catalog: APB487796.
KainicAcid Monohydrate (Digenin, Kainicacid hydrate). Group: Biochemicals. Alternative Names: (2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid;hydrate. Grades: Highly Purified. CAS No. 58002-62-3. Pack Sizes: 10mg, 50mg. Molecular Formula: C10 H15 NO4 H2, Molecular Weight: 231.2. US Biological Life Sciences.
Worldwide
(-)-α-KainicAcid
(-)-α-KainicAcid. Group: Biochemicals. Alternative Names: (2S,3S,4S)-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid; 2-Carboxy-4-isopropenyl-3-pyrrolidineacetic Acid; (-)-KainicAcid; (2S,3S,4S)-2-Carboxy-4-isopropenylpyrrolidine-3-acetic Acid; Digenic Acid; Digenin; Helminal; KainicAcid; L-α-KainicAcid; α-KainicAcid. Grades: Highly Purified. CAS No. 487-79-6. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
(?)-(α)-KainicAcid hydrate
A naturally occurring neuroexcitatory chemical that is a selective agonist for a subtype of ionotropic glutamate receptor. Synonyms: (2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid hydrate. Grades: ≥98%. CAS No. 58002-62-3. Molecular formula: C10H15NO4·H2O. Mole weight: 231.2.
A neuroexcitatory chemical that is selective for the kainicacid receptor. Group: Biochemicals. Alternative Names: ([2S-(2a,3ß,4ß)]-2-Caroxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac kainicacid
rac kainicacid. Group: Biochemicals. Alternative Names: ([rel-(2a,3b,4b)]-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid; (2R,3S,4S)-rel-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid. Grades: Highly Purified. CAS No. 73209-05-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C10H15NO4. US Biological Life Sciences.
Worldwide
Decursin
Decursin is a coumarin from The roots of Peucedanum ostruthium. Coumarins, such as decursinol and decursin, are known to be the major compounds of A. gigas. Angelica gigas roots have been widely used traditionally in Korean herbal medicine not only for the treatment of anaemia, but also as a sedative, an anodyne and a tonic. Studies have shown that decursin inhibits VEGF-mediated inner BRB breakdown through suppression of VEGFR-2 signaling pathway. And decursin is able to attenuate kainicacid-induced seizures and could have potential as an antiepileptic drug. Uses: Enzyme activators. Synonyms: 2-Butenoic acid, 3-methyl-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester (9CI); 2-Butenoic acid, 3-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester, (S)-; Crotonic acid, 3-methyl-, ester with 7,8-dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one, (+)- (8CI); 2H,6H-Benzo[1,2-b:5,4-b']dipyran, 2-butenoic acid deriv. Grades: > 98%. CAS No. 5928-25-6. Molecular formula: C19H20O5. Mole weight: 328.36.
Domoic Acid
Domoic acid is an excitatory amino acid isolated from the red alga Chondria armata Okamura, Rhodomelaceae. Domoic acid shown to be responsible for amnesic shellfish poisoning associated with ingestion of certain cultured blue mussels. Domoic acid is a structural analog of Kainicacid.Potent agonist at receptors for excitatory amino acids glutamate and kainate; has highest affinity for AMPA/kainate receptor of any kainate agonist; causes excessive excitation of neurons leading to depletion of energy stores. Group: Biochemicals. Alternative Names: (2S,3S,4S)-2-Carboxy-4-[(1Z,3E,5R)-5-carboxy-1-methyl-1,3-hexadien-1-yl]-3-pyrrolidineacetic Acid; (-)-Domoic Acid; L-Domoic Acid; NSC 288031. Grades: Highly Purified. CAS No. 14277-97-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??NO?, Molecular Weight: 311.33. US Biological Life Sciences.
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GT1b-Ganglioside (triammonium salt)
GT1b-Ganglioside is demonstrated to protect mouse brain cells against L-cysteine-induced damage of mitochondrial DNA and increased lipid peroxidation, suggested to operate through scavenging of OH radicals promoted by L-cysteine. GT1b-Ganglioside is also demonstrated to suppress seizures, damage to mitochondrial DNA and lipid peroxidation induced by kainicacid. Synonyms: Trisialoganglioside-GT1b (porcine brain, triammonium salt). Grades: >99%. CAS No. 59247-13-1. Molecular formula: C95H174N8O47. Mole weight: 2180.42.
Kynurenic acid
Kynurenic acid is a product of L-Tryptophan metabolism. It is a non-selective antagonist at NMDA and AMPA/kainate receptors. It could block kainicacid neurotoxicity. It has neruoactive activity having anticonvulsant and antiexcitotoxic properties. Uses: Excitatory amino acid antagonists. Synonyms: 4-Hydroxy-2-quinolinecarboxylic Acid; 4-Hydroxy-quinaldic Acid; 2-Carboxy-4-hydroxyquinoline; 4-Hydroxyquinaldic Acid; Quinurenic Acid; NSC 58973; 4-Hydroxyquinoline-2-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 492-27-3. Molecular formula: C10H7NO3. Mole weight: 189.17.
A potent and selective agonist of the putative, excitatory neurotransmitter L-glutamic acid. AMPA does not interfere with binding sites for kainicacid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists. Group: Biochemicals. Alternative Names: AMPA. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
A potent and selective agonist of the excitatory neurotransmitter L-glutamic Acid. AMPA does not interfere with binding sites for kainicacid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists. Group: Biochemicals. Alternative Names: AMPA, HBr. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
A potent and selective agonist of the putative, excitatory neurotransmitter L-glutamic acid. AMPA does not interfere with binding sites for kainicacid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists. Group: Biochemicals. Alternative Names: D,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid-13C2,15N; AMPA-13C2,15N ; D,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid-13C2,15N; γ-Amino-3-hydroxy-5-methylisoxazole-4-propionic Αcid-13C2,15N. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Tezampanel
Tezampanel, a decahydroisoquinoline derivative, has been found to be AMPA receptor as well as Kainicacid receptor antagonist that could probably be useful in studies of migraine, neuromuscular disorders and Thrombosis. Synonyms: Tezampanel;LY-293558;LY293558;LY293558;Ted-isoquinoline-3-COOH; (3S,4aR,6R,8aR)-6-[2-(2H-tetrazol-5-yl)ethyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid. Grades: 98%. CAS No. 154652-83-2. Molecular formula: C13H21N5O2. Mole weight: 279.34.
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