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10mg Pack Size. Group: Amino Acids, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C10H15NO4. CAS No. 487-79-6. Prepack ID 58606205-10mg. Molecular Weight 213.23. See USA prepack pricing.
Kainic acid
50mg Pack Size. Group: Amino Acids, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C10H15NO4. CAS No. 487-79-6. Prepack ID 58606205-50mg. Molecular Weight 213.23. See USA prepack pricing.
Kainic acid
excitory amino acid, neurotoxin, neurobiology tool. CAS No. 487-79-6. Product ID: 1-01136. Molecular formula: C10H15NO4. Mole weight: 213.23. Properties: soluble in 0.1 M NaOH. Reference: Neuropharmacology, 38, 991, 1999; Brain Develop., 21, 253, 1999; Brain Res., 791, 215, 1998; McGeer, Olney, McGeer, eds.) Kainic acid as a tool in neurobiology, Raven Press, NY 1978; Ann. Rev. Pharmacol. Toxicol., 21, 16, 1981.
Kainic acid
Kainic acid. Group: Biochemicals. Grades: Purified. CAS No. 487-79-6. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
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Kainic acid
Kainic acid is a naturally occurring neuroexcitatory amino acid. It is a selective agonist for a subtype of ainate-class ionotropic glutamate receptor found in seaweed. It increases production of mitochondrial dysfunction, reactive oxygen species and apoptosis in neurons in many regions of the brain. It increases glutamate release and stimulates Na channels, inducing epileptic seizures and neurocytosis (apoptosis). It has been used to study mechanisms of apoptosis and epilepsy. Uses: Excitatory amino acid agonists. Synonyms: (2S,3S,4S)-3-(carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid; 2-Carboxy-3-carboxymethyl-4-isopropenylpyrrolidine; (-)-α-Kainic Acid; Digenic Acid; Digenin; Helminal; L-α-Kainic Acid; α-Kainic Acid. Grades: ≥98% by HPLC. CAS No. 487-79-6. Molecular formula: C10H15NO4. Mole weight: 213.23.
Kainic acid
Kainic acid is a potent excitotoxic agent. Kainic acid hydrate also is an agonist for a subtype of ionotropic glutamate receptor. Kainic acid induces seizures [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 487-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2309.
Kainic acid
Kainic acid. Uses: For analytical and research use. Group: Impurity standards. CAS No. 487-79-6. Molecular Formula: C10H15NO4. Mole Weight: 213.23. Catalog: APB487796.
Kainic acid dimethyl ester hydrochloride
water soluble store desiccated at -20°C. CAS No. 108365-31-7. Product ID: 1-01137. Molecular formula: C12H19NO4. Mole weight: 241.29.
Kainic Acid Monohydrate (Digenin, Kainic acid hydrate). Group: Biochemicals. Alternative Names: (2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid;hydrate. Grades: Highly Purified. CAS No. 58002-62-3. Pack Sizes: 10mg, 50mg. Molecular Formula: C10 H15 NO4 H2, Molecular Weight: 231.2. US Biological Life Sciences.
Worldwide
(-)-α-Kainic Acid
(-)-α-Kainic Acid. Group: Biochemicals. Alternative Names: (2S,3S,4S)-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid; 2-Carboxy-4-isopropenyl-3-pyrrolidineacetic Acid; (-)-Kainic Acid; (2S,3S,4S)-2-Carboxy-4-isopropenylpyrrolidine-3-acetic Acid; Digenic Acid; Digenin; Helminal; Kainic Acid; L-α-Kainic Acid; α-Kainic Acid. Grades: Highly Purified. CAS No. 487-79-6. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
(?)-(α)-Kainic Acid hydrate
A naturally occurring neuroexcitatory chemical that is a selective agonist for a subtype of ionotropic glutamate receptor. Synonyms: (2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid hydrate. Grades: ≥98%. CAS No. 58002-62-3. Molecular formula: C10H15NO4·H2O. Mole weight: 231.2.
A neuroexcitatory chemical that is selective for the kainic acid receptor. Group: Biochemicals. Alternative Names: ([2S-(2a,3ß,4ß)]-2-Caroxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac kainic acid
rac kainic acid. Group: Biochemicals. Alternative Names: ([rel-(2a,3b,4b)]-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid; (2R,3S,4S)-rel-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid. Grades: Highly Purified. CAS No. 73209-05-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C10H15NO4. US Biological Life Sciences.
Worldwide
Decursin
Decursin is a coumarin from The roots of Peucedanum ostruthium. Coumarins, such as decursinol and decursin, are known to be the major compounds of A. gigas. Angelica gigas roots have been widely used traditionally in Korean herbal medicine not only for the treatment of anaemia, but also as a sedative, an anodyne and a tonic. Studies have shown that decursin inhibits VEGF-mediated inner BRB breakdown through suppression of VEGFR-2 signaling pathway. And decursin is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. Uses: Enzyme activators. Synonyms: 2-Butenoic acid, 3-methyl-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester (9CI); 2-Butenoic acid, 3-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester, (S)-; Crotonic acid, 3-methyl-, ester with 7,8-dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one, (+)- (8CI); 2H,6H-Benzo[1,2-b:5,4-b']dipyran, 2-butenoic acid deriv. Grades: > 98%. CAS No. 5928-25-6. Molecular formula: C19H20O5. Mole weight: 328.36.
Domoic Acid
Domoic acid is an excitatory amino acid isolated from the red alga Chondria armata Okamura, Rhodomelaceae. Domoic acid shown to be responsible for amnesic shellfish poisoning associated with ingestion of certain cultured blue mussels. Domoic acid is a structural analog of Kainic acid.Potent agonist at receptors for excitatory amino acids glutamate and kainate; has highest affinity for AMPA/kainate receptor of any kainate agonist; causes excessive excitation of neurons leading to depletion of energy stores. Group: Biochemicals. Alternative Names: (2S,3S,4S)-2-Carboxy-4-[(1Z,3E,5R)-5-carboxy-1-methyl-1,3-hexadien-1-yl]-3-pyrrolidineacetic Acid; (-)-Domoic Acid; L-Domoic Acid; NSC 288031. Grades: Highly Purified. CAS No. 14277-97-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??NO?, Molecular Weight: 311.33. US Biological Life Sciences.
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GT1b-Ganglioside (triammonium salt)
GT1b-Ganglioside is demonstrated to protect mouse brain cells against L-cysteine-induced damage of mitochondrial DNA and increased lipid peroxidation, suggested to operate through scavenging of OH radicals promoted by L-cysteine. GT1b-Ganglioside is also demonstrated to suppress seizures, damage to mitochondrial DNA and lipid peroxidation induced by kainic acid. Synonyms: Trisialoganglioside-GT1b (porcine brain, triammonium salt). Grades: >99%. CAS No. 59247-13-1. Molecular formula: C95H174N8O47. Mole weight: 2180.42.
Kynurenic acid
Kynurenic acid is a product of L-Tryptophan metabolism. It is a non-selective antagonist at NMDA and AMPA/kainate receptors. It could block kainic acid neurotoxicity. It has neruoactive activity having anticonvulsant and antiexcitotoxic properties. Uses: Excitatory amino acid antagonists. Synonyms: 4-Hydroxy-2-quinolinecarboxylic Acid; 4-Hydroxy-quinaldic Acid; 2-Carboxy-4-hydroxyquinoline; 4-Hydroxyquinaldic Acid; Quinurenic Acid; NSC 58973; 4-Hydroxyquinoline-2-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 492-27-3. Molecular formula: C10H7NO3. Mole weight: 189.17.
A potent and selective agonist of the putative, excitatory neurotransmitter L-glutamic acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists. Group: Biochemicals. Alternative Names: AMPA. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
A potent and selective agonist of the excitatory neurotransmitter L-glutamic Acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists. Group: Biochemicals. Alternative Names: AMPA, HBr. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
A potent and selective agonist of the putative, excitatory neurotransmitter L-glutamic acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists. Group: Biochemicals. Alternative Names: D,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid-13C2,15N; AMPA-13C2,15N ; D,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid-13C2,15N; γ-Amino-3-hydroxy-5-methylisoxazole-4-propionic Αcid-13C2,15N. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Tezampanel
Tezampanel, a decahydroisoquinoline derivative, has been found to be AMPA receptor as well as Kainic acid receptor antagonist that could probably be useful in studies of migraine, neuromuscular disorders and Thrombosis. Synonyms: Tezampanel;LY-293558;LY293558;LY293558;Ted-isoquinoline-3-COOH; (3S,4aR,6R,8aR)-6-[2-(2H-tetrazol-5-yl)ethyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid. Grades: 98%. CAS No. 154652-83-2. Molecular formula: C13H21N5O2. Mole weight: 279.34.
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