Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Keratin 18 (272-283) | Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood. |  |
| Keratin-8 human | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Keratin 8 variant, partial (226-236) | Keratin 8 variant, partial (226-236) is a bioactive peptide of Keratin 8 variant. Keratin 8 helps to link the contractile apparatus to dystrophin at the costameres of striated muscle with KRT19 together. | |
| Keratin 8 variant, partial (253-264) | Keratin 8 variant, partial (253-264) is a bioactive peptide of Keratin 8 variant. Keratin 8 helps to link the contractile apparatus to dystrophin at the costameres of striated muscle with KRT19 together. | |
| Keratinase | Keratinase (KerA) is a protease that are able to degrade keratins into amino acids [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KerA. CAS No. 37341-53-0. Pack Sizes: 500 U. Product ID: HY-E70193. |  |
| Keratinase, Recombinant | Keratinase is a particular class of extracellular proteolytic inducible enzyme with the capability of degrading insoluble keratin substrates. It is important for hydrolyzing hair, feather, and collagen in sewage system during waste water treatment. It is also useful in food industry, animal feed preparation etc. Insoluble feather keratin from poultry industry may be converted by enzymatic hydrolysis to glues, feedstuffs, fertilizers, films or used for the production of rare amino acids serine, cysteine and proline. Applications: Keratinase was used for enzymatic treatment of elementary body (eb), gag molecules, and cells in the study of the role glycosaminoglycans (gags) in the invasion of host cells by chlamydia pneumoniae strains. Group: Enzymes. Synonyms: Keratinase; KerA; Keratinase from Bacillus licheniformis; Keratinolytic protease; EC 3.4.21. Enzyme Commission Number: EC 3.4.21. Keratinase. Mole weight: ~39 kDa. Activity: 300 - 1000 units/mg. Storage: Store at -20°C. Form: Lyophilized powder. Source: E. coli BL21. Keratinase; KerA; Keratinase from Bacillus licheniformis; Keratinolytic protease; EC 3.4.21. Cat No: NATE-0853. |  |
| Keratin from human epidermis | aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Keratin, Hydrolyzed | Protein serving structural and protective functions, present in hair and skin. Group: Biochemicals. Grades: Highly Purified. CAS No. 69430-36-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences. |  Worldwide |
| Keratinocyte Growth Factor human | KGF, recombinant, expressed in E. coli, powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Keratinocyte Transfection Kit | Transfection Reagent for Keratinocyte Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1784. |  Nevada, Texas, USA |
| Anti-Keratinocyte Growth Factor antibody produced in goat | affinity isolated antibody, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-phospho-Keratin 18 (pSer33) antibody produced in rabbit | affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-phospho-Keratin 18 (pSer52) antibody produced in rabbit | affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-phospho-Keratin 8 (pSer432) antibody produced in rabbit | affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-phospho-Keratin 8 (pSer73) antibody produced in rabbit | affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Hydrolyzed Keratin Peptide Powder (Food Grade) | Hydrolyzed Keratin Peptide Powder (Food Grade). Categories: l-citrulline; citrulline. |  CA, FL & NJ |
| Native Bacillus licheniformis Keratinase (feed grade) | Keratinase is a particular class of extracellular proteolytic inducible enzyme with the capability of degrading insoluble keratin substrates. It is important for hydrolyzing hair, feather, and collagen in sewage system during waste water treatment. It is also useful in food industry, animal feed preparation etc. Insoluble feather keratin from poultry industry may be converted by enzymatic hydrolysis to glues, feedstuffs, fertilizers, films or used for the production of rare amino acids serine, cysteine and proline. Group: Enzymes. Synonyms: KerA; Keratinolytic protease; EC 3.4.21. Enzyme Commission Number: EC 3.4.21. Keratinase. Form: Powder. Source: Bacillus licheniformis. Keratinase; KerA; Keratinase from Bacillus licheniformis; Keratinolytic protease; EC 3.4.21. Cat No: FEED-0001. | |
| Transglutaminase 1 from Human keratinocyte, Recombinant | Transglutaminase is based on the TGM1-allele from I.M.A.G.E.-clone IRAKp961M1628 isolated from human skin squamous cell carcinoma. It is N-terminally fused to a hexahistidine-tag resulting in the encoded N-terminal amino acid sequence MHHHHHHMDGPR. Transglutaminase is purified by IMAC to more than 90 % purity. Applications: This product catalyzes acyl transfer reactions from glutamin residues in proteins or peptides to primary amines, e. g. the formation of ε-(γ-glutamyl) lysine bonds between proteins by transferring the acyl group of a peptide-bound glutamine residue to the primary amino group of a peptide-bound lysine residue. this enzyme may also ...odansylcadaverine-incorporation into N,N-dimethylated casein according to Lorand et al., Anal. Biochem. 44 (221-231)]. Appearance: White lyophilized solid. Storage: Store at ≤ - 20°C. Store working aliquots at ≤ - 20°C. Avoid repeated freezing and thawing.Delivery at ambient temperature is possible. Form: The transglutaminase is lyophilized from 50 mM Tris-HCl pH 8.0, 10 mM Glutathion. Source: E. coli. Species: Human. transglutaminase; EC 2.3.2.13; 80146-85-6; transglutaminase; Factor XIIIa; fibrinoligase; fibrin stabilizing factor; glutaminylpeptide γ-glutamyltransferase; polyamine transglutaminase; tissue transglutaminase; R-glutaminyl-peptide:amine & | |
| 1- (Trimethoxysilyl) methanamine | An organosilane found in a compound composition used for lightening and/or dyeing of keratin fibers. Group: Biochemicals. Alternative Names: (Aminomethyl) trimethoxysilane; SLM 88705. Grades: Highly Purified. CAS No. 71408-48-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C4H13NO3Si. US Biological Life Sciences. | Worldwide |
| 25-Hydroxytachysterol3 | 25-Hydroxytachysterol3 is the metabolite of Vitamin D3 (HY-15398). 25-Hydroxytachysterol3 inhibits the proliferation of epidermal keratinocytes and dermal fibroblasts, stimulates the expression of differentiation- and antioxidant-related genes in keratinocytes. 25-Hydroxytachysterol3 activates vitamin D receptor ( VDR ) and aryl hydrocarbon receptor ( AhR ), liver X receptor α/β ( LXR α/β ) and peroxisome proliferator-activated receptor γ ( PPARγ ), stimulates the expression of CYP24A1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 39932-44-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-77278. | |
| Acetyl Glycyl Beta-Alanine | Acetyl Glycyl Beta-Alanine is a synthetic peptide that has been shown to effectively reduce hyperpigmentation and improve skin clarity. It works by inhibiting the formation and transfer of melanin, which are key processes in skin pigmentation. This peptide has the ability to interfere with the transcriptional and translational processes of melanin-promoting enzymes, significantly disrupting both the transport of melanosomes and the phagocytotic mechanism during melanosome transfer to keratinocytes. As a result, it brightens the skin, reduces dark spots, and improves overall skin tone. Clinical studies have demonstrated its efficacy in age and dark spot reduction, even skin tone, and skin lightening. It is an instant whitening agent that is widely used in skin care products and is particularly suitable for whitening and anti-aging products. Synonyms: Ac-Gly-bAla-OH; 3-(2-Acetamidoacetamido)propanoic acid; N-Acetylglycyl-beta-alanine; Ac-Gly-beta-Ala-OH; N-Acetyl-glycyl-beta-alanine; 3-(2-Acetylamino-acetylamino)propionic acid; β-Alanine, N-acetylglycyl-; Ac-Gly-β-Ala-OH. Grade: ≥95%. CAS No. 1016788-34-3. Molecular formula: C7H12N2O4. Mole weight: 188.18. | |
| Adapalene Elastic Liposome | Adapalene (ADA) is a synthetic retinoid that belongs to the class of topical anti-acne drugs. It regulates the differentiation of keratinocyte cells, promotes keratin dissolution, and has anti-inflammatory and anti-seborrheic effects. However, it can cause irritation and photosensitivity. This product is a pre-formulated liposome encapsulating Adapalene. This product uses Tween-80 to increase elasticity, facilitating easier drug penetration through the skin. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. |  |
| Adapalene Flexible Liposome | Adapalene (ADA) is a synthetic retinoid that belongs to the class of topical anti-acne drugs. It regulates the differentiation of keratinocyte cells, promotes keratin dissolution, and has anti-inflammatory and anti-seborrheic effects. However, it can cause irritation and photosensitivity. This product is a pre-formulated liposome encapsulating Adapalene. This product is formulated with propylene glycol to enhance its deformability, making the drug more permeable through the skin. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| Adapalene Liposome | Adapalene (ADA) is a synthetic retinoid that belongs to the class of topical anti-acne drugs. It regulates the differentiation of keratinocyte cells, promotes keratin dissolution, and has anti-inflammatory and anti-seborrheic effects. However, it can cause irritation and photosensitivity. This product is a pre-formulated liposome encapsulating Adapalene. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| Adapalene Thermosensitive Liposome | Adapalene (ADA) is a synthetic retinoid that belongs to the class of topical anti-acne drugs. It regulates the differentiation of keratinocyte cells, promotes keratin dissolution, and has anti-inflammatory and anti-seborrheic effects. However, it can cause irritation and photosensitivity. This product is a pre-formulated liposome encapsulating Adapalene. This product incorporates DPPC, which releases the drug at temperatures ranging from 39 to 42°C. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. | |
| Alprostadil alfadex | Alprostadil alfadex has a protective effect on radiation-induced proliferative inhibition and apoptosis in keratinocytes and healing of radiation-induced skin injury. Synonyms: Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,13E,15S)-, compd. with α-cyclodextrin (1:1); 2,4,7,9,12,14,17,19,22,24,27,29-Dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane, α-cyclodextrin deriv.; α-Cyclodextrin, compd. with (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid (1:1); G 511; PGE1 α-CD; PGE1-α-cyclodextrin inclusion compd.; Prostaglandin E1-α-cyclodextrin compd.; Prostaglandin E1-α-cyclodextrin inclusion compd.; Tandetoron. Grade: ≥95%. CAS No. 55648-20-9. Molecular formula: C36H60O30.C20H34O5. Mole weight: 1327.32. | |
| Betamethasone hydrochloride | Betamethasone hydrochloride is the hydrochloride of betamethasone, which is a synthetic corticosteroid and agonist of glucocorticoid receptor. It does not cause water retention. It has shown the inflammatory response by the betamethasone-receptor complex modulated the activity of certain genes, altering the production and activity of proteins. It has also revealed to inhibit keratinocyte proliferation. It has anti-inflammatory and immunosuppressive properties. Uses: Betamethasone hydrochloride inhibits keratinocyte proliferation. it has anti-inflammatory and immunosuppressive properties. Grade: >98 %. CAS No. 956901-32-9. Molecular formula: C22H30ClFO5. Mole weight: 428.92. | |
| Bisindolylmaleimide VIII acetate | Selective protein kinase C (PKC) inhibitor. Inhibits proliferation of cultured mouse epidermal keratinocytes. Enhances Fas- and TRAIL-mediated apoptosis. Inhibits T cell-mediated autoimmune diseases. Inhibits stimulation of insulin secretion by glucose. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2). Group: Biochemicals. Alternative Names: Ro 31-7549, BIM VIII. Grades: Highly Purified. CAS No. 138516-31-1. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H22N4O2. CH3COOH. US Biological Life Sciences. | Worldwide |
| BMS480404 | BMS480404 is a potent small molecule inhibitor. It bounds to human keratinocyte fatty acid-binding protein. Synonyms: BMS-480404; BMS 480404; (S)-2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-hydroxyacetic acid. Grade: 98%. CAS No. 533889-36-0. Molecular formula: C22H18Cl2O5. Mole weight: 433.28. | |
| Bodyfensine | Bodyfensine, a skin product described as acetyl dipeptide-3 aminohexanoate (Lipotec), is a tripeptide that plays a significant role in reinforcing the skin's natural defense system. It acts on keratinocytes, inducing the expression of human β-defensins 2 and 3, which strengthens the skin's innate resistance and maintains the balance between commensal microorganisms and pathogens on the skin surface, thereby reducing the risk of infection. Bodyfensine is particularly effective in controlling oil production and combating acne, making it suitable for various anti-acne and anti-comedonal skincare products. It is recognized for its ability to enhance skin resistance, reduce sebum secretion, and increase skin moisturization, contributing to a healthier and more balanced complexion. Synonyms: Acetyl Dipeptide-3 Aminohexanoate; Acetyl Tripeptide (Ac-R-Ahx-A). Grade: ≥95%. CAS No. 1265905-30-3. Molecular formula: C17H32N6O5. Mole weight: 400.47. | |
| Casein Kinase II Inhibitor IV Hydrochloride | Casein Kinase II Inhibitor IV Hydrochloride is a small-molecule inducer of epidermal keratinocyte differentiation. Synonyms: 3-(3-{2-[(3,4,5-Trimethoxyphenyl)amino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}phenyl)propanenitrile hydrochloride (1:1); Benzenepropanenitrile, 3-[2-[(3,4,5-trimethoxyphenyl)amino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-, hydrochloride (1:1). Grade: ≥98%. Molecular formula: C24H24ClN5O3. Mole weight: 465.93. | |
| Cholesteryl sulfate sodium | Cholesteryl sulfate sodium is an orally available, NPC2 -targeted cholesterol biosynthesis agonist. Cholesteryl sulfate sodium activates SREBP2 by competitively binding to NPC2, promoting cholesterol synthesis ( EC 50 =50 μM). Cholesteryl sulfate sodium enhances the self-assembly ability of Mitoxantrone hydrochloride (HY-13502A), while repairing the intestinal mucosal barrier and inhibiting inflammation by regulating serine protease activity and PKCη signaling pathway. Cholesteryl sulfate sodium is a component of the platelet cell membrane and supports platelet adhesion. Cholesteryl sulfate sodium also regulates the activity of selective protein kinase C isoforms and modulates the specificity of PI3K, playing a role in keratinocyte differentiation [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 2864-50-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111355B. | |
| Decapeptide-18 | Decapeptide-18, also known as CG-WINT, is a synthetic peptide that plays a significant role in promoting hair growth. It is composed of arginine, cysteine, glutamine, glutamic acid, histidine, threonine and valine. It is derived from the Wnt10 signaling pathway and is designed to stimulate the formation of hair placodes, which are essential for hair follicle development. This peptide exhibits higher stability and skin penetration compared to the natural Wnt10 peptide, making it effective in activating hair follicles and promoting the differentiation of hair follicle epithelial stem cells into hair keratinocytes. Additionally, Decapeptide-18 is recognized for its potential in enhancing hair density and strength, making it a valuable ingredient in hair care formulations aimed at combating hair loss and promoting hair growth. Synonyms: CG-WINT; Decapeptide 18. Grade: ≥95%. CAS No. 3032916-63-2. | |
| Dermcidin-1L (human) | The protein dermcidin expressed in sweat glands is secreted into the sweat and transported to the epidermal surface. The concomitant processing of the protein yields a broad-spectrum antimicrobial 47 amino acid peptide, dermcidin-1 (DCD-1). Dermcidin and naturally occurring DCD-1L fragments do not interfere with membrane permeability and bind to different surface molecules. DCD-1L stimulates keratinocytes to produce cytokines and chemokines such as TNF-α, IL-8, CXCL10 and CCL20. Synonyms: DCD-1L (human); H-Ser-Ser-Leu-Leu-Glu-Lys-Gly-Leu-Asp-Gly-Ala-Lys-Lys-Ala-Val-Gly-Gly-Leu-Gly-Lys-Leu-Gly-Lys-Asp-Ala-Val-Glu-Asp-Leu-Glu-Ser-Val-Gly-Lys-Gly-Ala-Val-His-Asp-Val-Lys-Asp-Val-Leu-Asp-Ser-Val-Leu-OH. Grade: ≥95%. CAS No. 478898-18-9. Molecular formula: C210H359N57O71. Mole weight: 4818.50. | |
| D-Galactose-6-O-sulphate sodium salt | It is an ingredient in some types of carrageenan and is also present in keratin sulfate. Synonyms: Gal-6S sodium salt; D-Galactose 6-(Hydrogen Sulfate) Sodium Salt (1:1); D-galactose-6-sulfate sodium; Sodium 6-O-sulfonato-D-galactopyranose; D-Galactopyranose 6-(sulfuric acid sodium) salt; sodium ((2R,3R,4S,5R)-3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl)methyl sulfate. Grade: ≥95%. CAS No. 125455-62-1. Molecular formula: C6H11O9SNa. Mole weight: 282.20. | |
| D-Glucosamine-6-O-sulphate | It is a component of heparin, heparin sulfate, keratin sulfate, and cell surface glycoconjugates. Synonyms: D-Glucosamine 6-Sulfate; GLCN-6S; {[(2R,3S,4R,5R)-5-amino-2,3,4-trihydroxy-6-oxohexyl]oxy}sulfonic acid; 2-Amino-2-deoxy-6-O-sulfo-D-glucose; D-Glucose, 2-amino-2-deoxy-, 6-(hydrogen sulfate). Grade: ≥95%. CAS No. 91674-26-9. Molecular formula: C6H13NO8S. Mole weight: 259.23. | |
| Diethyl Phosphate-13C4 Sodium Salt | Labeled Diethyl Phosphate. Used in a cosmetic composition for treating keratin materials. Group: Biochemicals. Alternative Names: Phosphoric Acid Diethyl Ester-13C4 Sodium Salt; Ethyl Sodium Phosphate-13C4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Efalizumab | Efalizumab is a targeted T cell modulator, and is a humanized monoclonal antibody of CD11a , the α subunit of LFA-1. Efalizumab inhibits T cell activation, cutaneous T cell trafficking, and T cell adhesion to keratinocytes, can be used for plaque psoriasis research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 214745-43-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9947. | |
| Fmoc-L-tyrosine | N-Fmoc-L-tyrosine is an N-Fmoc-protected form of L-Tyrosine. L-Tyrosine is an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines in human keratinocytes, and also for the synthesis of proteins and thyroid hormones. Synonyms: Fmoc-L-Tyr-OH; Fmoc-L-Tyrsine; FMOC-TYROSINE; 9-fluorenylmethyloxycarbonyl tyrosine; FMOC-TYR-OH. Grade: ≥ 98% (HPLC). CAS No. 92954-90-0. Molecular formula: C24H21NO5. Mole weight: 403.60. | |
| Fumaric Acid Monoethyl Ester | Fumaric Acid Monoethyl Ester is an anti-psoriatic fumaric acid ester. Fumaric Acid Monoethyl Ester inhibited thymidine-14C incorporation into DNA by cultured human lymphocytes. Fumaric Acid Monoethyl Ester has been shown to evoke transient increase in intracellular free calcium concentration and inhibit proliferation of human keratinocytes. Group: Biochemicals. Alternative Names: (2E)-2-Butenedioic Acid 1-Ethyl Ester; (2E)-2-Butenedioic Acid Monoethyl Ester; Fumaric Acid Ethyl Ester; (E)-4-Ethoxy-4-oxo-2-butenoic Acid; Ethyl Hydrogen Fumarate; Monoethyl Fumarate; Monoethyl Fumerate; Monoethyl trans-2-Butenedioate. Grades: Highly Purified. CAS No. 2459-5-4. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| GNF351 | GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC50 of 62 nM. GNF351 is minimal toxicity in mouse or human keratinocytes[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1227634-69-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-102023. | |
| Griseofulvin (Amudane, Grisovin, Fulvicin, Curling factor, Gricin, Grifulvin, Grisactin, Fulcin,. Norofulvin, Likuden, Idifulvin NSC 34533) | Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important asect to the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy. Group: Biochemicals. Grades: Highly Purified. CAS No. 126-07-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Histamine dihydrochloride | Histamine dihydrochloride is a reactive oxygen species ( ROS ) inhibitor. Histamine dihydrochloride can suppress ROS production and work together with IL-2 to activate T cells and NK cells, leading to immune activation in the tumor microenvironment, which consequently kills acute myeloid leukemia (AML) cells. Histamine dihydrochloride can cause a reduction in vaginal tetrazo reduction, increased epithelial growth, and heightened keratinization in mouse models of ovariectomy. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 56-92-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-B0722. | |
| Immobilized Proteinase K on Eupergit(R) C | Proteinase K hydrolyses keratin by cleaving peptide bonds adjacent to the carboxyl group of aliphatic and aromatic amino acids. Group: Enzymes. Synonyms: Tritirachium alkaline proteinase; Tritirachium album serine proteinase; proteinase K; Tritirachium album proteinase K; endopeptidase K; EC 3. 4. 21. 64; 39450-01-6. Enzyme Commission Number: EC 3. 4. 21. 64. Activity: >1500 U/g. Storage: 2-8°C. Form: powder (granular). Source: Tritirachium album. Tritirachium alkaline proteinase; Tritirachium album serine proteinase; proteinase K; Tritirachium album proteinase K; endopeptidase K; EC 3. 4. 21. 64; 39450-01-6; Immobilized Proteinase K. Cat No: NATE-1776. | |
| Ingenol-3-angelate | Ingenol 3-Angelate is a diterpenoid ester isolated from Euphorbia peplus that induces rapid cell death with keratinocytes and some cancer cell lines. Ingenol 3-Angelate is a protein kinase C activator that displays potent antileukemic activity. Ingenol 3-Angelate (ingenol mebutate) is used for treatment of actinic keratosis.Source:Semi-synthetic, the starting material ingenol was isolated from Euphorbia latyris. Group: Biochemicals. Grades: Highly Purified. CAS No. 75567-37-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C25H34O6. US Biological Life Sciences. | Worldwide |
| Kojic acid | Kojic acid is a substance produced by Aspergillus oryzae that is orally effective and can also be absorbed transdermally. Kojic acid exhibits various biological activities, including anti-aging, anti-nematode, antimicrobial, antioxidant, and anti-inflammatory effects. Kojic acid is a Tyrosinase inhibitor with an Mushroom Tyrosinase IC 50 of 182.7 μM. Kojic acid prevents melanin production by capturing copper ions that bind to the tyrosinase active site, thus inhibiting its activation. Kojic acid also suppresses the NF-κB and p21 signaling pathways in human keratinocytes. Kojic acid derivatives have anticancer activity [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. CAS No. 501-30-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W050154. | |
| Lactosamine | Lactosamine forms the backbone of several cell surface glycans such as sialylated glycans or keratin sulfates. Also, it is a basic structural element of Lewis type, and human milk oligosaccharides. Group: Biochemicals. Grades: Highly Purified. CAS No. 13000-25-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C12H23NO10, Molecular Weight: 341.31. US Biological Life Sciences. | Worldwide |
| L-Alaninefrom non-animal source | L-Alanine, a non-essential amino acid, is produced enzymatically from L-aspartate using aspartate β-decarboxylase. It is the smallest among all the aminoacids. Uses: L-alanine has been used for tissue culture technique as a media component. it has been used as a media component for the growth of adult mouse keratinocytes. Additional or Alternative Names: (S)-2-Aminopropionic acid, L-α-Aminopropionic acid. Product Category: Amino Acids. CAS No. 56-41-7. Mole weight: 89.09. Canonical SMILES: C[C@H](N)C(O)=O. ECNumber: 200-273-8. Product ID: ACM56417-6. Alfa Chemistry ISO 9001:2015 Certified. |  |
| L-Cystine | L-cystine is a sulfur-containing amino acid, which exists in small amounts in proteins, and is mostly contained in keratin of hair and fingers. Often used as a nutritional supplement, it is widely used in the breastfeeding of milk powder. It is a non-essential amino acid. CAS No. 56-89-3. Product ID: CDF4-0221. Molecular formula: C6H12N2O4S2. Category: Amino acid. Product Keywords: Amino Acids; L-Cystine; CDF4-0221; Amino acid; C6H12N2O4S2; 56-89-3. Grade: Food Grade. Color: White. EC Number: 200-296-3. Physical State: Powder/Solid. Solubility: 1 M HCl: 100 mg/mL. Storage: 2-8°C. Boiling Point: 468.2±45.0 °C(Predicted). Melting Point: >240 °C (dec.) (lit.). Density: 1.68. |  |
| L-Histidine | L-Histidine is a proteinogenic amino acid and an essential amino acid required for histamine production. This positively charged amino acid is vital for growth, tissue repair, myelin sheath maintenance, and histamine synthesis. Histamine plays critical roles in immunity, gastric secretion, and more. L-Histidine is essential for blood cell production and tissue protection against radiation and heavy metals. L-Histidine plays a role as a metabolite and also acts as a cofactor in enzyme protection during protein synthesis. It is an L-enantiomer of histidine and is necessary for histamine synthesis and human development. L-Histidine finds applications in cell culture, metabolomics and biochemical research. Uses: L-histidine has been used as a component in agar plates containing 5-fluorocytosine (5-fc) for the selection of yeast transformants. it has also been used as a component of adult mouse keratinocyte growth medium. Additional or Alternative Names: (S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773. Product Category: Amino Acids. CAS No. 71-00-1. Molecular formula: C6H9N3O2. Mole weight: 155.15. Canonical SMILES: N[C@@H](Cc1c[nH]cn1)C(O)=O. Density: 1.4±0.1 g/cm3. ECNumber: 200-745-3. Product ID: ACM71001-2. Alfa Chemistry ISO 9001:2015 Certified. | |
| Lipoxin A4 | Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties [1]. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways [2]. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC 50 value of 25.74 nM [3]. Uses: Scientific research. Group: Natural products. Alternative Names: LXA4. CAS No. 89663-86-5. Pack Sizes: 25 μg (283.71 μM * 250 μL in Ethanol). Product ID: HY-113509. | |
| L-Tyrosine tert-butyl ester | L-Tyrosine tert-butyl ester is a protected form of L-Tyrosine. L-Tyrosine is an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines in human keratinocytes, and also for the synthesis of proteins and thyroid hormones. Synonyms: L-Tyr-OtBu; H-Tyr-OtBu; tert-Butyl L-tyrosinate; L-tyrosine-COOBu-t; L-Tyrosine tert-butyl ester; t-butyl ester of tyrosine. Grade: ≥ 99% (HPLC). CAS No. 16874-12-7. Molecular formula: C13H19NO3. Mole weight: 237.30. | |
| Lugdunin | Lugdunin is an antibiotic peptide. Lugdunin inhibits bacteria by dissipating their membrane potential. Lugdunin is active against Gram-positive bacteria, such as S. aureus , and reduces S. aureus skin and nasal colonization. Lugdunin induces LL-37 and CXCL8/MIP-2 in human keratinocytes and mouse skin [1]. Uses: Scientific research. Group: Peptides. CAS No. 1989698-37-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P4200. | |
| Myristoyl Hexapeptide-16 | Myristoyl Hexapeptide-16 is a synthetic lipo-peptide known for its ability to stimulate the growth of eyelashes and hair. It is composed of a six-amino acid peptide sequence (Leu-Lys-Lys-Thr-Glu-Thr) attached to the oil-soluble fatty acid, myristic acid, which enhances its bioavailability. This peptide has the capacity to significantly activate keratin genes, which are responsible for the production of keratin, a key structural protein in the skin and hair. By activating these genes, Myristoyl Hexapeptide-16 promotes the growth and thickening of eyelashes and hair, making it a popular ingredient in eyelash serums and hair care products. In addition to its effects on hair growth, Myristoyl Hexapeptide-16 is also recognized for improving skin's resilience and contributing to a smoother, calmer skin appearance. It works by enhancing the production of keratin, which is fundamental to the structure of the skin, thus providing skin with added strength and smoothness. Overall, Myristoyl Hexapeptide-16 is a versatile ingredient used in cosmetic formulations to promote hair growth and improve skin texture. Synonyms: Myristoyl-Leu-Lys-Lys-Ala-Leu-Lys-OH; Myristoyl-LKKALK; N-Myristoyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-lysine; N-(1-Oxotetradecyl)-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-lysine; Myristoyl hexapeptide 16. Grade: ≥98%. CAS No. 959610-54-9. Molecular formula: C47H91N9O8. Mole weight: 910.28. | |
| Myristoyl Pentapeptide-12 | Myristoyl Pentapeptide-12 is a synthetic peptide that is recognized for its potential to promote hair growth, particularly for eyelashes and eyebrows, by stimulating keratin gene expression and enhancing the development of the dermal papilla, which is crucial for hair growth. In addition to its effects on hair, Myristoyl Pentapeptide-12 has also been noted for its ability to improve the appearance of the skin by increasing keratinocyte proliferation, which can lead to improved skin firmness, elasticity, and thickness. This peptide enhances skin firmness and elasticity, making it a valuable ingredient in skincare formulas designed to reduce signs of aging and improve skin texture. | |
| Myristoyl Pentapeptide-17 | Myristoyl Pentapeptide-17 is a synthetic peptide used for skin care and eyelash growth. It activates the keratin gene, which causes eyelashes to grow and thicken. Synonyms: N2-(1-Oxotetradecyl)-L-lysyl-L-leucyl-L-alanyl-L-lysyl-L-lysinamide. CAS No. 959610-30-1. Molecular formula: C41H81N9O6. Mole weight: 796.14. | |
| Myristoyl pentapeptide-4 | Myristoyl pentapeptide-4, a signaling peptide targeting keratin, is a bioactive peptide that has the effect of promoting hair growth and is used as a cosmetic ingredient. Synonyms: Myristoyl pentapeptide 4; L-Serine, N2-(1-oxotetradecyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-; N2-(1-Oxotetradecyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-serine; MYR-KTTKS; myristoyl pentapeptide-3; myristoyl-Lys-Thr-Thr-Lys-Ser-OH; N-myristoyl-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-serine. Grade: >95%. CAS No. 1392416-25-9. Molecular formula: C37H71N7O10. Mole weight: 774.00. | |
| Octinoxate | Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Octyl methoxycinnamate. CAS No. 5466-77-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1234. | |
| Oligopeptide-34 | Oligopeptide-34 is a synthetic peptide consisting of 13 amino acids, including arginine, aspartic acid, isoleucine, glutamine, leucine, serine, threonine, and tryptophan. It is used in cosmetics for its skin-brightening, whitening, and spot-fading effects. This peptide works by reducing melanin synthesis and tyrosinase activity in melanocytes, which are the cells responsible for producing melanin. Additionally, it decreases the transfer of melanosomes, which are the packages of melanin pigment, to new keratinocytes, the cells of the epidermis. Oligopeptide-34 can significantly reduce melanin production and tyrosinase enzyme activity, making it an effective ingredient for treating hyperpigmentation and evening out skin tone. It is considered a safe and effective alternative to hydroquinone for skin whitening. Synonyms: CG-TGP2; Oligopeptide 34. Grade: ≥95%. CAS No. 2227218-62-2. | |
| rec β-Defensin 2 (human) | β-Defensin 2 (BD-2) (human), an antimicrobial peptide expressed throughout the epithelia of many organs, is induced when keratinocytes come into contact with Gram-negative bacteria or pro-inflammatory cytokines such as TNF-α and IL-1β. Elevated expression has been detected in lesional epidermal keratinocytes both in psoriasis and inflamed skin of mastitis. Synonyms: rec hBD-2; rec BD-2 (human); rec Defensin b-2 (human). Grade: ≥95% by HPLC. CAS No. 479328-13-7. | |
| Retinol palmitate | It can transdermally absorb, resist keratinization, stimulate the growth of collagen and elastin, and increase the thickness of epidermis and dermis. Enhances skin elasticity, effectively eliminates wrinkles, promotes skin renewal, maintains skin vitality. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Vitamin A palmitate, all-trans-Retinol palmitate. Product Category: Material of cosmetics. CAS No. 79-81-2. Molecular formula: C36H60O2. Mole weight: 524.86. Product ID: ACM79812. Alfa Chemistry ISO 9001:2015 Certified. Categories: Retinyl palmitate. | |
| Suberoyl Bis-hydroxamic Acid | Histone deacetylase inhibitor. A cell-permeable inhibitor of HDAC1 and HDAC3. Shown to suppresses the growth of proliferating keratinocytes and squamous cell carcinoma cells. Group: Biochemicals. Alternative Names: N1, N8-Dihydroxyoctane diamide. Grades: Highly Purified. CAS No. 38937-66-5. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| Tachysterol | Bioactive, synthetic vitamin D3 analog; exhibits anti-proliferative effect on keratinocytes. Anti-psoriatic. Group: Biochemicals. Alternative Names: (1S)-3-[(1E)-2-[(1R,3aR,7aR)-2,3,3a,6,7,7a-Hexahydro-7a-methyl-1-[(1R,2E,4R)-1,4,5-trimethyl-2-hexen-1-yl]-1H-inden-4-yl]ethenyl]-4-methyl-3-cyclohexen-1-ol; (3 β,6E,22E)-9,10-Secoergosta-5(10),6,8,22-tetraen-3-ol; Provitamin D; Tachysterin2; Tachysterol2. Grades: Highly Purified. CAS No. 115-61-7. Pack Sizes: 1mg. Molecular Formula: C??H??O, Molecular Weight: 396.65. US Biological Life Sciences. | Worldwide |
| TB500 | TB500 is a synthetic version of an active region of thymosin β 4. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation [1]. Uses: Scientific research. Group: Peptides. CAS No. 885340-08-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0170. | |
| Terrein (NSC 291308, 4,5-Dihydroxy-3-(1-propenyl)-2-cyclopenten-1-one) | Antibacterial. Phytotoxin. Melanogenesis inhibitor by reducing tyrosinase production via extracellular signal-regulated protein kinase (ERK) activation. Keratinocyte and epidermis proliferation inhibitor. Mycotoxin. Anti-inflammatory modulator in pulpal inflammation. Angiogenesis inhibitor through angiogenin secretion inhibition. Collagen-induced platelet aggregation inhibitor. Antioxidant agent that enhances osseointegration by decreasing the level of ROS and having a potentially synergistic effect on osteoblast differentiation. Proteasome inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 582-46-7. Pack Sizes: 1mg, 5mg, 10mg. US Biological Life Sciences. | Worldwide |
| TGF α (1-50) (rat) | TGF α (1-50) (rat) was originally identified as an agent that can reversibly confer a transformed phenotype on normal non-tumor cells, such as normal rat renal fibroblasts. This activity requires the presence of transforming growth factor-β (TGF-β), which enhances the effects of TGF-α through a separate receptor. TGF-α is synthesized by monocytes, keratinocytes and a variety of tissues and tumors. (approx. ED50 = 0.2 ng/mL). Synonyms: H-Val-Val-Ser-His-Phe-Asn-Lys-Cys-Pro-Asp-Ser-His-Thr-Gln-Tyr-Cys-Phe-His-Gly-Thr-Cys-Arg-Phe-Leu-Val-Gln-Glu-Glu-Lys-Pro-Ala-Cys-Val-Cys-His-Ser-Gly-Tyr-Val-Gly-Val-Arg-Cys-Glu-His-Ala-Asp-Leu-Leu-Ala-OH (Disulfide bridge: Cys8-Cys21, Cys16-Cys32, Cys34-Cys43); Transforming Growth Factor-α (1-50) from rat. CAS No. 89899-53-6. Molecular formula: C244H361N71O71S6. Mole weight: 5617.38. | |
| trans 2-Phenylcyclopropylamine Hydrochloride (Tranylcypromine, trans 2-Amino-1-phenyl-cyclopropane Hydrochloride) | A non-selective inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC50 <2uM for BHC110/LSD1). When combined with GSK-3 Inhibitor CHIR99021, causes reprogramming of human primary keratinocyte transduced with two factors, Oct4 and Klf4. Group: Biochemicals. Alternative Names: Tranylcypromine; trans 2-Amino-1-phenyl-cyclopropane Hydrochloride. Grades: Highly Purified. CAS No. 1986-47-6. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Tranylcypromine Hemisulfate (Trans (±) -2-Phenyl cyclopropanamine, Hemisulfate; SKF trans-355; 2-PCPA) | An inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC50 <2uM for BHC110/LSD1). When combined with GSK-3 Inhibitor CHIR99021, causes reprogramming of human primary keratinocyte transduced with two factors, Oct4 and Klf4. Group: Biochemicals. Alternative Names: Trans (±) -2-Phenyl cyclopropanamine, Hemisulfate; SKF trans-355; 2-PCPA. Grades: Highly Purified. CAS No. 13492-01-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Undecane | Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α [. Uses: Scientific research. Group: Natural products. CAS No. 1120-21-4. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-N8593. | |
| Undecanoic acid | Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Undecanoate; Hendecanoic acid. CAS No. 112-37-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W004282. | |
Our database is helping our users find suppliers everyday.
